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Статті в журналах з теми "Multi-Photon microscope"
Piston, David W. "Multi-Photon Excitation Microscopy: An Old Idea in Quantum Theory Applied to Modern Scientific Problems." Microscopy and Microanalysis 6, S2 (August 2000): 1180–81. http://dx.doi.org/10.1017/s1431927600038393.
Повний текст джерелаvan Hook, Lee. "Entangled Microscopy." Microscopy Today 7, no. 3 (April 1999): 6–7. http://dx.doi.org/10.1017/s1551929500064038.
Повний текст джерелаJason Kirk. "Beyond the Hype - Is 2-Photon Microscopy Right for You?" Microscopy Today 11, no. 2 (April 2003): 26–29. http://dx.doi.org/10.1017/s1551929500052469.
Повний текст джерелаDenk, Winfried. "Multi-Photon Microscopy, High Resolution Imaging Deep in Strongly Scattering Specimens." Microscopy and Microanalysis 3, S2 (August 1997): 301–2. http://dx.doi.org/10.1017/s1431927600008394.
Повний текст джерелаSo, P. T. C., C. Y. Dong, C. Buhler, and E. Gratton. "Time-Resolved Stimulated-Emission Fluorescence Microscope." Proceedings, annual meeting, Electron Microscopy Society of America 54 (August 11, 1996): 278–79. http://dx.doi.org/10.1017/s042482010016385x.
Повний текст джерелаChen, Dihan, Mindan Ren, Dapeng Zhang, Jialong Chen, Songyun Gu, and Shih-Chi Chen. "Design of a multi-modality DMD-based two-photon microscope system." Optics Express 28, no. 20 (September 24, 2020): 30187. http://dx.doi.org/10.1364/oe.404652.
Повний текст джерелаChuah, J., and D. Holburn. "Scalable and Configurable Multi-pixel CMOS Photon Detector for the Scanning Electron Microscope." Microscopy and Microanalysis 18, S2 (July 2012): 1222–23. http://dx.doi.org/10.1017/s1431927612007969.
Повний текст джерелаPegoraro, A., A. Ridsdale, RK Lyn, JP Pezacki, and A. Stolow. "Simple High Performance Multi-modal Coherent Anti-Stokes Raman Scattering (CARS) Microscopy Based on a Two-Photon Microscope." Microscopy and Microanalysis 14, S2 (August 2008): 758–59. http://dx.doi.org/10.1017/s1431927608086911.
Повний текст джерелаGeorge, Nicholas M., Arianna G. Polese, Greg Futia, Baris Ozbay, Wendy Macklin, Emily Gibson, Aviva Abosch, Diego Restrepo, and Brian E. Moore. "2507 A novel multi-photon microscopy method for neuronavigation in deep brain stimulation surgery." Journal of Clinical and Translational Science 2, S1 (June 2018): 2–3. http://dx.doi.org/10.1017/cts.2018.40.
Повний текст джерелаVlieg, Redmar C., and John van Noort. "Multiplexed two-photon excitation spectroscopy of single gold nanorods." Journal of Chemical Physics 156, no. 9 (March 7, 2022): 094201. http://dx.doi.org/10.1063/5.0073208.
Повний текст джерелаДисертації з теми "Multi-Photon microscope"
Chuah, Joon Huang. "A multi-pixel CMOS photon detector for the scanning electron microscope." Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608077.
Повний текст джерелаGuillemant, Marie. "Development of a three-photon microscope for awake and behaving non-human primates." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASL025.
Повний текст джерелаMulti-photon microscopy has become a standard technique to study the structural and functional activity in mice but it faces obstacles to be applied in larger animals. It would be particularly advantageous to be able to apply it to macaque monkeys, as they are the animal model of choice to understand the neural mechanisms of high-level cognitive functions such as selective attention, working memory and consciousness. One of the main limiting factors for imaging in larger animals is the dura mater. This tough and opaque layer of tissue protects the brain but is so thick in larger animals that it obstructs imaging. It is therefore commonly removed but this leads to a highly invasive and unstable preparation. The main aim of the current work is to investigate the possibility to record functional activity from the cortex of the rhesus macaque monkey through the natural dura.A multi-photon microscopy setup has been designed with a two-photon and a three-photon microscopy optical paths to record from awake macaque monkeys. The repetition rate of the laser is 2MHz which allows a maximum imaging depth inside the cortex of 520µm at 960nm and 715µm at 1300nm with an additional 120µm-thick layer of dura mater at the surface. Resonance-galvo scanning is used to allow a maximal frame rate of 15.6Hz at a field of view of 620x630µm². In addition to the setup, surgical implants have been developed for long-term and awake imaging.Using an ex vivo study of dura mater from a macaque monkey, the induced optical aberrations are studied by measuring the decrease in spatial resolution of the setup for a varying thickness of dura mater. This reveals that it has no significant impact on the spatial resolution for a thickness up to 150µm at 1300nm. The effective attenuation length of the dura mater is estimated to be 56.5±10.1µm at 960nm and 80.7±5.3µm at 1300nm. These measurements are used to model the maximum imaging depth that can be reached according to the repetition rate of the laser and the thickness of the dura.This model is adjusted and validated using in vivo data from two non-human primates. The effective attenuation length of the natural dura mater and of a regrowth of tissue following a durectomy (called a 'neomembrane') are investigated. Functional recordings have been performed in mice and preprocessed using Suite2P. Viral injection parameters have been tested in three macaque monkeys and we have so far recorded the in vivo structural and functional activity of neurons in one. Finally, the comparison between the use of two- and three-photon microscopy to study non-human primates is discussed. In conclusion, we have set up and optimized a multi-photon microscope for long-term awake imaging of the cortex of non-human primates and shown that it was possible to record down to over 700µm into the cortex (which corresponds to the layers L2/L3) while imaging through the natural dura mater or a neomembrane
Mansfield, Jessica. "Multi-photon microscopy of cartilage." Thesis, University of Exeter, 2008. http://hdl.handle.net/10036/42345.
Повний текст джерелаTsikritsis, Dimitrios. "Vibrational spectroscopy and microscopy in colorectal cancer." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/33049.
Повний текст джерелаRomijn, Elisabeth Inge. "Development of 3-D Quantitative Analysis of Multi-Photon Microscopy Images." Thesis, Norges teknisk-naturvitenskapelige universitet, Institutt for fysikk, 2012. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-18425.
Повний текст джерелаChalal, Mohand. "Structure multi-échelle et propriétés physico-chimiques des gels de polymères thermosensibles." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00680076.
Повний текст джерелаGasecka, Alicja. "Microscopie non-lineaire polarimetrique dans les milieux moleculaires et biologiques." Phd thesis, Université Paul Cézanne - Aix-Marseille III, 2010. http://tel.archives-ouvertes.fr/tel-00560415.
Повний текст джерелаGuiet, Romain. "Étude des mécanismes cellulaires et moléculaires de la migration des macrophages humains dans des environnements en trois dimensions." Toulouse 3, 2011. http://thesesups.ups-tlse.fr/1487/.
Повний текст джерелаTissue infiltration of macrophages is an aggravating factor in many diseases such as chronic inflammation and cancer. Macrophages that infiltrate tumors are called tumor-associated macrophages (TAMs). They promote tumor growth, angiogenesis, invasion and metastasis. Thus, inhibition of macrophage infiltration has become a therapeutic goal. Recently, the team demonstrated that macrophages use the amoeboid (depending on ROCK) or the mesenchymal (depending on proteases) migratory mode according to the extracellular matrix (ECM) architecture in three dimensions (3D). In addition, the study of the mesenchymal migration mode showed that it is dependent on Hck (a phagocyte-specific tyrosine kinase) and its ability to reorganize podosomes (ECM-degrading actin-rich structures) into rosettes. My thesis project was organized around two axes 1) the identification of substrates of Hck and the characterization of their role in the organization of podosomes and 3D migration of macrophages, and 2) the study of the 3D migration mechanisms of primary human monocytes/ macrophages within an in vitro tumor model: tumor cell spheroids. By a proteomic approach, I have identified potential partners and substrates of Hck, including the protein Filamin A (FLNa), a protein interacting with the actin cytoskeleton and integrins. Using different tools (recombinant proteins, antibodies, shRNA. . . ) I showed that: 1) Hck phosphorylates FLNa in vitro, 2) FLNa is localized to podosomes and is necessary for their organization as rosettes under the control of Hck, 3) the podosomes of FLNa-deficient cells have a shorter life span, and 4) the expression of FLNa is required for mesenchymal migration, but not for amoeboid migration of macrophages in a 3D ECM. Thus, FLNa could be a substrate of Hck necessary for the formation and stabilization of podosomes and their organization as rosettes, and is required for the mesenchymal migration of macrophages. In parallel, I developed a model of tumor cell spheroids, which allowed me to show that the infiltration of monocytes or macrophages in this in vitro tissue model of tumor is dependent on ROCK and proteases, signature of the use of the two migration modes. Then, when spheroids were embedded into ECM, I demonstrated that the presence of macrophages infiltrated into the spheroids is necessary to trigger the invasiveness of tumor cells. Indeed, macrophages infiltrate first the surrounding ECM and tumor cells follow macrophages in the matrix outside of the spheroid. Hck-/- macrophages, that are defective in mesenchymal migration, are significantly less effective in promoting the invasion of tumor cells. These results indicate that the activity of migration and matrix remodeling exerted by macrophages is prominent in tumor invasion. These results have established the migratory mode of macrophages infiltrating an in vitro tumor model and a mechanism required for tumor invasiveness promoted by macrophages. Thus during my thesis, I characterized the molecular and cellular mechanisms of 3D migration of human macrophages. Indeed, I have been able to: 1) identify a protein necessary for the mesenchymal migration of macrophages, 2) highlight the use by macrophages of the amoeboid and mesenchymal migration modes during their infiltration into an in vitro tumor model in 3D and 3) show that the matrix remodeling activity of macrophages during their migration plays a critical role in tumor cell invasion
Leclerc, Pierre. "Développement d’un endomicroscope multiphotonique à deux couleurs pour l’imagerie du métabolisme énergétique cellulaire." Thesis, Limoges, 2017. http://www.theses.fr/2017LIMO0053/document.
Повний текст джерелаNonlinear microscopy is a cutting edge imaging modality leading to remarkable step forward in biology but also in the clinical field. To use it at its full potential and at the very heart of clinical practice, there has been several development of fiber-based micro-endoscope. The application for those probes is now limited by few major restrictions, such as the impossibility to collect auto-fluorescence signal from tissues theses being inherently weak such as the fluorescence from NADH or FAD. This limitation reduces the usefulness of the micro-endoscope effectively restraining it to morphological imaging modality requiring staining of the tissue. Our aim is to go beyond this limitation, showing cellular metabolism monitoring, in real time, without any staining. The experimental setup is an upgrade of our precedent one where the reflection- based Grism stretcher is replace with a new generation transmission-based Grism stretcher. Another Laser was also added in order to tune the first laser at 860nm to allow FAD imaging and the second one to 760nm for NADH. The results prove that we assess and image the level of NADH and FAD at subcellular resolution through a five-meter-long fiber. Thus we demonstrate that we are capable of measuring the optical redox ratio in a micro-endoscopic configuration
Liu, Li. "Roles of PMCA Isoforms in Ca2+-Homeostasis and Contractility of Bladder Smooth Muscle: Evidence from PMCA Gene-Ablated Mice." Cincinnati, Ohio : University of Cincinnati, 2007. http://rave.ohiolink.edu/etdc/view.cgi?acc_num=ucin1178307168.
Повний текст джерелаAdvisor: Richard J. Paul. Title from electronic thesis title page (viewed Apr. 4, 2009). Keywords: PMCA (human gene symbols; ATP2B); SERCA2 (human gene symbols; ATP2A2); NCX; bladder smooth muscle; Ca²⁺ homeostasis; gene-altered mice. Ca²⁺ waves; Ca²⁺ sparks; Fura-PE3; Fluo-4; Indo-1; multi-photon microscopy. Includes abstract. Includes bibliographical references.
Книги з теми "Multi-Photon microscope"
Dickson, Andrew. Multi-Photon Laser Scanning Microscopy. Bios Scientific Pub Ltd, 2002.
Знайти повний текст джерелаDixon, John. Multi-Photon Laser Scanning Microscopy. Taylor & Francis Group, 2004.
Знайти повний текст джерелаDickson, Andrew. Multi Photon Laser Scanning Microscopy. Springer-Verlag Telos, 2002.
Знайти повний текст джерелаPetrov, V. V., A. A. Kryuchyn, Ie V. Beliak, and A. S. Lapchuk. Multi-Photon Microscopy and Optical Recording. PH "Akademperiodyka", 2016. http://dx.doi.org/10.15407/akademperiodyka.311.156.
Повний текст джерелаЧастини книг з теми "Multi-Photon microscope"
Bewersdorf, Jörg, Alexander Egner, and Stefan W. Hell. "Multifocal Multi-Photon Microscopy." In Handbook Of Biological Confocal Microscopy, 550–60. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-45524-2_29.
Повний текст джерелаSo, Peter T. C. "Multi-photon Excitation Fluorescence Microscopy." In Frontiers in Biomedical Engineering, 529–44. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-8967-3_35.
Повний текст джерелаMurti, Y. V. G. S., and C. Vijayan. "Basics of Multi-photon Microscopy." In Physics of Nonlinear Optics, 157–68. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-73979-9_9.
Повний текст джерелаKönig, Karsten. "Cell Damage During Multi-Photon Microscopy." In Handbook Of Biological Confocal Microscopy, 680–89. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-45524-2_38.
Повний текст джерелаSandoval, Ruben M., and Bruce A. Molitoris. "Fluorescent Dextrans in Intravital Multi-Photon Microscopy." In Advances in Intravital Microscopy, 205–19. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-017-9361-2_10.
Повний текст джерелаDenk, Winfried, David W. Piston, and Watt W. Webb. "Multi-Photon Molecular Excitation in Laser-Scanning Microscopy." In Handbook Of Biological Confocal Microscopy, 535–49. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-45524-2_28.
Повний текст джерелаHardin, Jeff. "Confocal and Multi-Photon Imaging of Living Embryos." In Handbook Of Biological Confocal Microscopy, 746–68. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-45524-2_43.
Повний текст джерелаMolitoris, Bruce A., and Ruben M. Sandoval. "Quantifying Dynamic Kidney Processes Utilizing Multi-Photon Microscopy." In Contributions to Nephrology, 227–35. Basel: KARGER, 2007. http://dx.doi.org/10.1159/000102088.
Повний текст джерелаGhafaryasl, Babak, Bart H. Bijnens, Erwin van Vliet, Fátima Crispi, and Rubén Cárdenes. "Cardiac Microstructure Estimation from Multi-photon Confocal Microscopy Images." In Functional Imaging and Modeling of the Heart, 80–88. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-38899-6_10.
Повний текст джерелаEgner, Alexander, and Stefan W. Hell. "Aberrations in Confocal and Multi-Photon Fluorescence Microscopy Induced by Refractive Index Mismatch." In Handbook Of Biological Confocal Microscopy, 404–13. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-45524-2_20.
Повний текст джерелаТези доповідей конференцій з теми "Multi-Photon microscope"
Marti, Dominik, Martin Djurhuus, Ole Bjarlin Jensen, and Peter E. Andersen. "Multi-photon microscope driven by novel green laser pump." In SPIE BiOS, edited by Ammasi Periasamy, Peter T. C. So, and Karsten König. SPIE, 2016. http://dx.doi.org/10.1117/12.2208586.
Повний текст джерелаGonçalves, Odete, Scott Snider, Ruben Zadoyan, Quoc-Thang Nguyen, Henrik Vorum, Steffen B. Petersen, and Maria Teresa Neves-Petersen. "Novel microfabrication stage allowing for one-photon and multi-photon light assisted molecular immobilization and for multi-photon microscope." In SPIE BiOS, edited by Samuel Achilefu and Ramesh Raghavachari. SPIE, 2017. http://dx.doi.org/10.1117/12.2250567.
Повний текст джерелаSchenkl, Selma, Eike Weiss, Martin Stark, Frank Stracke, Iris Riemann, Robert Lemor, and Karsten König. "Imaging living cells with a combined high-resolution multi-photon-acoustic microscope." In Biomedical Optics (BiOS) 2007, edited by Alexander A. Oraevsky and Lihong V. Wang. SPIE, 2007. http://dx.doi.org/10.1117/12.702391.
Повний текст джерелаMilster, Tom D., Youngsik Kim, and Phat Lu. "Hyper-NA (NA = 2.8) Microscope Using 1.55um fs Source for Multi-Photon Imaging." In Bio-Optics: Design and Application. Washington, D.C.: OSA, 2013. http://dx.doi.org/10.1364/boda.2013.bt1a.2.
Повний текст джерелаTjokro, Cahyadi, and Colin J. R. Sheppard. "Phase space analysis of photon scattering in multi planes within a microscope system." In SPIE Proceedings, edited by Valery V. Tuchin. SPIE, 2006. http://dx.doi.org/10.1117/12.697072.
Повний текст джерелаMatsumoto, Naoya, Shigetoshi Okazaki, Hisayoshi Takamoto, Takashi Inoue, and Susumu Terakawa. "Modulation of the pupil function of microscope objective lens for multifocal multi-photon microscopy using a spatial light modulator." In SPIE BiOS, edited by Ammasi Periasamy, Peter T. C. So, and Karsten König. SPIE, 2014. http://dx.doi.org/10.1117/12.2038929.
Повний текст джерелаSquier, Jeffrey A. "A Pragmatic Guide to Building a Multi-Photon Microscope with Applications to Micro-Machining." In CLEO: Applications and Technology. Washington, D.C.: OSA, 2013. http://dx.doi.org/10.1364/cleo_at.2013.ctu3o.4.
Повний текст джерелаYavaş, S., M. Erdoğan, K. Gürel, U. H. Tazebay, and F. Ö. Ilday. "Multi-photon ablation of biological samples with custom-built femtosecond fiber laser-microscope system." In Conference on Lasers and Electro-Optics. Washington, D.C.: OSA, 2010. http://dx.doi.org/10.1364/cleo.2010.jwa73.
Повний текст джерелаKarpf, Sebastian, and Bahram Jalali. "Spectrally-encoded Multi-photon Microscopy." In Novel Techniques in Microscopy. Washington, D.C.: OSA, 2017. http://dx.doi.org/10.1364/ntm.2017.nm4c.4.
Повний текст джерелаHirao, K. "Writing Waveguides and Gratings in Silica and Related Materials by Femto-Second Laser." In Bragg Gratings, Photosensitivity, and Poling in Glass Fibers and Waveguides. Washington, D.C.: Optica Publishing Group, 1997. http://dx.doi.org/10.1364/bgppf.1997.btub.4.
Повний текст джерела