Статті в журналах: "Moisturiser"

1

Shumack, Stephen P., and Chris A. Commens. "MOISTURISER PRESCRIPTION PATTERNS AMONG AUSTRALASIAN DERMATOLOGISTS." Australasian Journal of Dermatology 29, no. 3 (December 1988): 151–53. http://dx.doi.org/10.1111/j.1440-0960.1988.tb00388.x.

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Lim, Adrian C., and Susanne Freeman. "Allergic contact dermatitis to an expired moisturiser." Australasian Journal of Dermatology 44, no. 4 (November 2003): 291–94. http://dx.doi.org/10.1046/j.1440-0960.2004.00024.x.

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Hayama, Koremasa, Yusaku Takano, Jin Tamura, Hachiro Tagami, and Tadashi Terui. "Effectiveness of a heparinoid-containing moisturiser to treat senile xerosis." Australasian Journal of Dermatology 56, no. 1 (October 10, 2014): 36–39. http://dx.doi.org/10.1111/ajd.12179.

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4

Harianti, Santi Fitri, and Kun Harismah. "Natural Moisturizer Based Formulation of Green Grass Jelly (Cyclea Barbata Miers) with Aloe Vera Addition." Jurnal Dedikasi 17, no. 1 (June 2, 2020): 20. http://dx.doi.org/10.22219/dedikasi.v17i1.12078.

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Moisturizer is one of cosmetics used for dry skin care and can make skin become moist and soft. Natural material can be used to maintain water content in the skin and soften skin is Aloe vera. Aloe vera contains minerals, vitamins A, C, E and B12. In addition to Aloe vera to maintain antioxidants in the skin is green grass jelly because it has flavonoid content. Content contained in Aloe vera and green grass jelly can be used for making natural moisturizers because at this time many moisturizers that contain harmful chemicals. This observation was to analyze differences in concentration of Aloe vera and green grass jelly on moisturizers and analyze antioxidant activity of green grass jelly. Method used in making this moisturizer is mixing with green grass jelly formulation (2.5%; 5%; 7.5%) + Aloe vera (2.5%, 5%, 7.5%, 10%), and non-sample formulation treatment. Analysis of this experimental data was qualitative on moisturizers and quantitatively to calculate levels of flavonoids in green grass jelly. Results of this study indicate that difference in concentration of Aloe vera + green grass jelly greatly affects parameters of good moisturizer used, and greater addition of green grass jelly concentration greater flavonoid content in moisturizer.

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Kang, Seok-Young, Ji-Young Um, Bo-Young Chung, So-Yeon Lee, Jin-Seo Park, Jin-Cheol Kim, Chun-Wook Park, and Hye-One Kim. "Moisturizer in Patients with Inflammatory Skin Diseases." Medicina 58, no. 7 (July 1, 2022): 888. http://dx.doi.org/10.3390/medicina58070888.

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As interest in skin increases, the cosmetic market is also growing. It is difficult to choose between the numerous types of basic cosmetics on the market. This article aims to provide advice and guidance on which products to recommend according to a patient’s skin condition. Appropriate application of a moisturizer attempts not only to improve the dryness, but also improve the skin’s natural barrier function to protect the skin from internal and external irritants to keep the skin healthy. Moisturizers consist of various ingredients, including occlusive agents, emollients, humectants, lipid mixture, emulsifiers, and preservatives. Pathophysiology of dry skin is also discussed to provide readers with the background they need to choose the right moisturizer for themselves. As moisturizers play an important role as adjuvant in the treatment of common skin diseases, such as atopic dermatitis, contact dermatitis, psoriasis, acne and rosacea, which type of moisturizer is appropriate for each disease was also dealt with. Basic cosmetics, especially moisturizers, should be recommended in consideration of the ingredients, effectiveness and safety of each product, and the skin condition of each patient.

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Shi, Vivian Y., Negar Foolad, Jennifer Ornelas, Waqas Burney, Melody Maarouf, Lauren Hassoun, Gabriela Monico, et al. "The Comparative Effects of Various Moisturizers on Epidermal Barrier Function Recovery After Bathing in Atopic Dermatitis." SKIN The Journal of Cutaneous Medicine 2, no. 4 (July 6, 2018): 219–23. http://dx.doi.org/10.25251/skin.2.4.3.

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Background/Aims: An important pillar of AD management involves moisturizer application following bathing to restore epidermal barrier function (EBF). In this study, we aim to bring additional evidence to the “soak-and-smear” regimen, comparing EBF recovery by various moisturizers following bathing in AD and healthy subjects. Methods: Volar forearms of 10 AD patients and 10 healthy controls were immersed in water for 10 minutes to simulate bathing. Immediately after bathing, ceramide-containing emollient (CER), a humectant (10% glycerin, GLY), an occlusant (white petrolatum, PETR), and aloe vera 5% extract (ALOE) were applied to separate test sites on the forearm. One test site did not receive any moisturizer and served as control. EBF parameters (hydration, TEWL, and pH) were recorded at baseline, and 15, 30, and 60-minutes post-bathing.Results: AD and controls shared similar trends. ALOE had the most significant pH decrease while GLY had the highest pH increase. Hydration significantly increased in all moisturizers compared to control. GLY led to the highest increase, peaking at 15-minutes for both AD and healthy subjects. AD subjects had higher hydration following CER than healthy subjects throughout the entire study. All four moisturizers increased TEWL compared to control, though PETR had the lowest initial TEWL increase. Conclusion: All moisturizers has an immediate effect on improving SC hydration. Their initial effects on TEWL increase recovers toward control levels by 60-minutes. Future studies are needed to examine the effect of repeated moisturizer post-bathing over longer study periods.

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Morino, Ichiko, Aika Okuno, Yuka Hirakawa, Yumiko Saya, Yumi Murakami, Fukumi Furukawa, and Hiroshi Matsunaka. "Epidermal Growth Factor Inhibitor-induced Cutaneous Toxicity Improves with Moisturizers." Trends in Immunotherapy 4, no. 2 (November 15, 2020): 35. http://dx.doi.org/10.24294/ti.v4.i2.1187.

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Although epidermal growth factor receptor (EGFR) inhibitors are one of the most effective treatment options for lung cancer, they frequently cause cutaneous toxicity that can lead to treatment discontinuation. Dryness, which is a common form of cutaneous toxicity, is usually treated using medical moisturizing agents. We aimed to investigate the treatment of cutaneous toxicity caused by EGFR inhibitors by comparing patients who used a cosmetic moisturizer with those who used conventional medical moisturizers. This study included 12 patients with lung cancer, who were receiving EGFR inhibitors and using topical medical moisturizers. The participants were assigned to a group that continued using medical moisturizers or a group that began using NOV® skin cream D. The study’s findings showed that like conventional medical moisturizers, NOV®skin cream D improved the cutaneous dryness caused by EGFR inhibitors and that it might additionally improve patients’ quality of life. Also, we obtained novel findings that NOV® skin cream D normalized keratinization, which is a component of normal skin cell differentiation impeded by EGFR inhibitors. Hence, the cosmetic moisturizer may help to prevent the discontinuation of EGFR inhibitors, thereby ensuring their continuous therapeutic effects.

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8

Ciampi, Elisabetta, Michael van Ginkel, Peter J. McDonald, Simon Pitts, Eleanor Y. M. Bonnist, Scott Singleton, and Ann-Marie Williamson. "Dynamic in vivo mapping of model moisturiser ingress into human skin by GARfield MRI." NMR in Biomedicine 24, no. 2 (September 15, 2010): 135–44. http://dx.doi.org/10.1002/nbm.1562.

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9

Mawazi, Saeid Mezail, Jo Ann, Noordin Othman, Jiyauddin Khan, Sultan Othman Alolayan, Sultan S. Al thagfan, and Mohammed Kaleemullah. "A Review of Moisturizers; History, Preparation, Characterization and Applications." Cosmetics 9, no. 3 (June 9, 2022): 61. http://dx.doi.org/10.3390/cosmetics9030061.

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Moisturizers are one of the most widely used preparations in cosmetics and have been extensively used to soften the skin for consumers. Moisturizers work effectively in combating dry skin which may cause pain, tightness, itch, stinging, and/or tingling. The aim of this review is to evaluate published studies on the history, ingredients, preparation processes, characteristics, uses, and applications of moisturizers. Moisturizers bridge the gap between medicine and consumer goods by being used to make the skin more beautiful and healthy. In the future, in moisturizer therapy, the capacity to adapt specific agents to specific dermatological demands will be crucial. Cosmetically, moisturizers make the skin smooth by the mechanism of increasing the water content in the stratum corneum, hence exerting its most vital action, which is moisturizing action and maintaining a normal skin pH.

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10

Rakhma, Dita Nurlita, Yuyun Nailufa, Yuli Ainun Najih, and Hery Wahjudi. "Optimization of Skin Moisturizer Formula Based on Fixed Oil (VCO, Olive Oil, and Jojoba Oil)." Journal of Pharmacy and Science 6, no. 2 (July 24, 2021): 109–14. http://dx.doi.org/10.53342/pharmasci.v6i2.221.

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Currently, formulations of skin moisturizers are derived from natural compounds. Fixed oils are known to have compounds that potential to be developed as skin moisturizers based on emollient mechanism. Therefore, this study aims to determine the effect of oil type on the physical characteristics of skin moisturizer creams. In this study, a skin moisturizer cream was formulated using three types of fixed oils: VCO (F1), Olive Oil (F2), and Jojoba Oil (F3). All formulas were tested for physical characteristics of pH, cream type, viscosity, spreadability, and homogeneity. The test results show that all formulas appropriate to the skin pH range, have o/w type creams and homogeneous texture. In the results of the viscosity test, there was a significant difference (p<0.05) with the highest value of viscosity for F2 (16750 ± 250 cP) > F3 (14200 ± 346cP) > F1 (5833 ± 58 cP), while for spreadability test there were also significant differences (p<0.05) with the highest diameter for F1 (5.8 ± 0.1 cm) = F3 (5.7 ± 0.2 cm) > F2 (4.3 ± 0.2 cm). Based on the results, it can be concluded that the type of oil can affect the physical characteristics of the moisturizer formula. F1 and F3 have better physical characteristics than F2.

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Erwan, Friesca, Syaifullah Muhammad, Raihan Dara Lufika, Eva Oktaviana, Nadiatul Azizah, Elza Badriati Miftah, Fathan Mubin, Luthfiah Zahra Larosa, and Siti Hajar. "Experimental Design of Lip Moisturizer as a Patchouli-Based Innovation Product." Journal of Patchouli and Essential Oil Products 1, no. 1 (April 29, 2022): 14–17. http://dx.doi.org/10.24815/jpeop.v1i1.23748.

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Patchouli oil, a type of essential oil, is one of Indonesian’s non-oil and gas export commodities accounted for one of the sources of Indonesian foreign exchange. Patchouli alcohol is commonly used in the cosmetic and perfume industries as well as the fragrance ingredient in the household products, one of which is used in lip moisturizer product. Lip moisturizer is a cosmetic product that was created with the similar essence of lipstick saves for its colorless in nature hence the translucent appearance. As a moisturizer, lip moisturizer can be used to moisturize the lips to avoid dry and chapped lips. Producing lip moisturizer involves four steps of formulation, which are mixing the solid components, mixing the liquid components, mixing of both the solid and liquid components, and adding the active substances and the patchouli oil. The study conducted two times of experiment, and it can be concluded that the second experiment can be used for lip skin. The execution of the test was based on the stability and homogeneity tests that meet the terms and conditions that have been set.

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12

LEE, M. G., and P. MORRIS. "Effect of Replens vaginal moisturiser on latex rubber condoms: a comparison with oil and water based preparations." International Journal of Pharmacy Practice 2, no. 4 (June 1994): 240–41. http://dx.doi.org/10.1111/j.2042-7174.1994.tb00771.x.

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13

Lutfiah Nur Fitria, M. Abdul Jabar, Nurliya Dzulfiana, Sylva Ayu Widya Cahyati, and Nia Yuniarsih. "Natural Ingredients with Potential as Skin Moisturizers (Body Lotion): A Narrative Literature Review." Archives of The Medicine and Case Reports 3, no. 4 (June 16, 2022): 293–95. http://dx.doi.org/10.37275/amcr.v3i4.213.

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Hand and body lotion is a skin moisturizing cosmetic preparation that belongs to the emollient (softener) class and has several properties, namely as a source of moisture for the skin, making hands and body soft but not greasy and easy to apply on the skin. Currently, there are quite a lot of moisturizers on the market, but most of them contain several compounds that have the potential to cause interference with the barrier and skin structure. Therefore, it is necessary to carry out a comprehensive exploration effort in order to develop a moisturizer that is safer against the barrier and skin structure. Some natural ingredients that have the potential to be developed as skin moisturizers are papaya latex, yam, VCO (virgin coconut oil), and cocoa fat.

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&NA;. "Oestrogen-free vaginal moisturiser can improve comfort and QOL for women undergoing breast cancer treatment with aromatase inhibitors." Inpharma Weekly &NA;, no. 1470 (January 2005): 5. http://dx.doi.org/10.2165/00128413-200514700-00011.

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15

Martin, Kathleen. "In vivo Measurements of Water in Skin by Near-Infrared Reflectance." Applied Spectroscopy 52, no. 7 (July 1998): 1001–7. http://dx.doi.org/10.1366/0003702981944652.

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Near-infrared (NIR) reflectance spectroscopy has been used to differentiate water in different hydrogen-bonding environments of skin in vivo and to determine the effect of moisturizer application on water content. Four types of water have been observed in the second-derivative spectrum of skin. These are assigned as water associated with the lipid bilayers, primary and secondary water of hydration on protein, and bulk (free) water in deeper tissue. The intensities of the lipid-associated water band and the bulk water band depend on anatomical site. The latter, particularly, may be affected by corneocyte size and may have potential in predicting transdermal penetration of drugs. Moisturizer application appears to have little effect on water content, but results in changes in the degree of scattering of radiation, suggesting that moisturizers smooth, rather than hydrate, the skin.

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Wijayadi, Linda Julianti, and Kelvin Kelvin. "The Role of Essential Oils on Improving Elderly Skin Hydration." Science Midwifery 10, no. 4 (October 13, 2022): 3104–11. http://dx.doi.org/10.35335/midwifery.v10i4.769.

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Skin hydration has an important role in various diseases of the elderly. Skin hydration is determined by two factors, namely the ability of the stratum corneum (SC) to retain water due to natural moisturizing factors and the barrier function of the intercellular lipid lamellar structure and tight junctions. Several parameters are usually used for skin hydration, such as surface water content (SWC) and trans-epidermal water loss (TEWL). With age, several changes in the skin affect hydration, including changes in the cellular and intercellular lipid matrix, skin pH, SC protease enzymes, decreased sebaceous and sweat gland activity, and decreased estrogen levels in women. Therefore, a moisturizer is needed to minimize the unwanted effects of some of these changes. Selection of the type of moisturizer is very important for the elderly, especially moisturizers with antiseptic, antibacterial, and antioxidant effects are highly recommended. The ability of essential oils as components of moisturizers has been proven in various studies. Essential oils can improve the function of the epidermal barrier and help prevent transepidermal water loss. Therefore, this literature review discusses the role of various essential oils, namely green tea oils (Camellia sinensis or Camellia assamica), virgin coconut oils (Cocos nucifera L.), evening primrose oils (Oenothera paradoxa), grape seed oils (Vitis vinifera L.) .), rosemary oils (Rosmarinus officinalis L.), immortelle oils (Helichrysum italicum), and cannabis seeds oils (Cannabis sativa L.) on improving skin hydration in the elderly.

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Moore, Zena, Declan Patton, Pinar Avsar, Natalie L. McEvoy, Gerard Curley, Aglecia Budri, Linda Nugent, Simone Walsh, and Tom O'Connor. "Prevention of pressure ulcers among individuals cared for in the prone position: lessons for the COVID-19 emergency." Journal of Wound Care 29, no. 6 (June 2, 2020): 312–20. http://dx.doi.org/10.12968/jowc.2020.29.6.312.

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Objective: Pressure ulcers (PUs) involve the destruction of skin and underlying tissue due to prolonged pressure and shear forces. These ulcers are painful and significantly reduce a person's quality of life. PUs are also expensive to manage and impact negatively on the achievement of cost-effective, efficient care delivery. Method: Prone positioning is a postural therapy that aims to enhance respiratory function through increasing oxygenation levels. In contemporary clinical practice, ventilation in the prone position is indicated for patients with severe acute respiratory distress syndrome. However, despite its advantages in terms of respiratory function, several studies have examined complications of prone position ventilation and have identified PUs (facial PUs as well as PUs on other weight-bearing areas of the body) as a frequent complication in patients who are already in a precarious medical situation. International data suggest that up to 57% of patients nursed in the prone position develop a PU. The aim of this clinical review is to identify and review evidence-based recommendations developed to facilitate the selection and application of preventive interventions aimed at reducing PU development in patients ventilated in the prone position. Given the current COVID-19 crisis, this review is timely as intensive care unit (ICU) patients with COVID-19 require ventilation in the prone position at a level that is disproportionate to the general intensive care population. Up to 28% of patients admitted to the ICU with confirmed infection due to severe COVID-19 are cared for in the prone position. The scope of this review is limited to adult individuals only. Results: The skin assessment should be undertaken before proning and following positioning the patient back into the supine position. Although it is essential to keep the skin clean and moisturised, using pH-balanced cleansers, there is inconsistency in terms of the evidence to support the type of moisturiser. Use of positioning devices in addition to repositioning is recommended to offload pressure points on the face and body. Further, using dressings such as hydrocolloids, transparent film and silicone may be of benefit in decreasing facial skin breakdown. Conclusion: Given the importance of PU prevention in this cohort of patients, adopting a focused prevention strategy, including skin assessment and care, offloading and pressure redistribution, and dressings for prevention may contribute to a reduction in the incidence and prevalence of these largely preventable wounds.

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Cohen, Stephanie R., Jesús A. Cárdenas-de la Garza, Paige Dekker, Wasim Haidari, Sarah S. Chisolm, Sarah L. Taylor, and Steven R. Feldman. "Allergic Contact Dermatitis Secondary to Moisturizers." Journal of Cutaneous Medicine and Surgery 24, no. 4 (April 15, 2020): 350–59. http://dx.doi.org/10.1177/1203475420919396.

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Background: Moisturizers are cosmetic products used routinely to manage various skin conditions. Even though moisturizers are often thought to have minimal or no adverse reactions, allergic contact dermatitis (ACD) to these products can develop in some cases. Methods: We studied ingredients included in 3 of the most commonly used moisturizer brands, identified their presence in standard patch testing series, and evaluated their allergenic potential, categorizing the allergens as frequent or infrequent. The standard patch testing series used as reference were the Thin-layer Rapid Use Epicutaneous patch test (T.R.U.E. test), the North American Contact Dermatitis Group (NACDG) screening standard series, and the American Contact Dermatitis Society (ACDS) core allergen series. Results: Aveeno, Cetaphil, and Cerave products had a total of 12, 14, and 9 potential allergens, respectively, the majority of which were infrequent and not included in standard patch testing series. Conclusion: Being aware of the allergenic potential of commonly used moisturizers may help healthcare providers when evaluating patients with ACD. Further testing is recommended in a targeted manner when suspecting ACD with negative standard patch testing series or when ACD is refractory to treatment.

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Voegeli, David, and Sarah Hillery. "Prevention and management of moisture-associated skin damage." British Journal of Nursing 30, no. 15 (August 12, 2021): S40—S46. http://dx.doi.org/10.12968/bjon.2021.30.15.s40.

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Disruption to the integrity of the skin can reduce patient wellbeing and quality of life. A major cause of skin breakdown is prolonged exposure to moisture, but this is often overlooked. When skin is wet, it becomes more susceptible to damage from friction and shearing forces, and skin flora can penetrate the disrupted barrier, causing further irritation and inflammation. If untreated, moisture-associated skin damage (MASD) can rapidly lead to excoriation and skin breakdown. MASD includes incontinence-associated dermatitis (IAD), which is caused by prolonged skin exposure to urine and stool, particularly liquid stool. For patients at a high risk of developing IAD, preventive measures should be instituted as soon as possible. The main one is to prevent excessive contact of the skin with moisture. Optimal skin care should be provided to patients with any form of MASD. It should be based on a structured regimen and include the use of a gentle skin cleanser, a barrier product and moisturiser. Derma Protective Plus is a liquid barrier that gives long-lasting protection against chafing or ingress of urine and stool into the skin. This product is less greasy than others, and provides a barrier and a healing environment, with resistance to further maceration from IAD or persistent loose stools.

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Lestari, Wahyu, Rita Meutia, and Mulia Saputra. "Innovation of the utilization of sale banana (pisang sale) made from awak banana (Musa paradisiaca cv. Awak) and kepok banana (Musa acuminata balbisiana Colla) into skin moisturizer (Inovasi pemanfaatan pisang sale yang terbuat dari pisang awak (Musa paradisiaca cv. Awak) dan pisang kepok (Musa acuminata balbisiana Colla) menjadi pelembab kulit)." Buletin Pengabdian Bulletin of Community Services 2, no. 3 (December 15, 2022): 70–74. http://dx.doi.org/10.24815/bulpengmas.v2i3.28154.

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Banana is one of the common fruits in Indonesia that can be processed into other products, such as Sale Banana which is one of the typical souvenirs from Aceh. The purpose of this community service activity (PkM) is to increase the income of business owners and Sale Banana traders. The community service location is dedicated to small and medium enterprises in Alue Naga Village, Banda Aceh. Through this PkM activities, Sale Banana is used to create a new product that is a moisturizing product for the skin. Two types of bananas are used in this PkM, namely Awak banana and Kepok banana. The extracts of the two bananas are used as the main ingredient of the moisturizer. The antioxidant activity of the two banana extracts was tested using the DPPH method. Based on the results of community service, skin moisturizers have an IC50 antioxidant activity of 10.52 (Kepok banana) and 14.00 (Awak banana). It could be concluded that both Sale Kepok Banana extract and Awak Banana extract have a strong antioxidant activity and could be used as a good moisturizer.

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Cahya, Cucu Arum Dwi, Aminah Syarifuddin, and Ahmad Syukur Syukur. "EFEKTIFITAS EKSTRAK ETANOL DAUN SAWI HIJAU (Brassica rapa Var. Parachinensis) SEBAGAI PELEMBAB KULIT DENGAN SEDIAAN MASKER PEEL-OFF." JURNAL FARMASIMED (JFM) 2, no. 1 (October 31, 2019): 6–15. http://dx.doi.org/10.35451/jfm.v2i1.292.

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Green mustard plants can be formulater into peel-off masks to moisturize the skin, because based on previous research green mustard leaves cointain flavonoids as antioxidants which can moisturize the skin. The purpose of this study was to find out green mustard leaves can be formulated into peel-off mask preparations and to find out the preparation and to find out the preparation off peel off mask with etanol extract of green mustard leaves can moisturize the skin. This study uses an experimental method. Green mustard leaves are extracted by maceration. In this study, a skin analyzer was usee as a mesure of skin moisture level after using peel off mask from a variety of dosage formulations which were divided into 5 preparations, blank (without mask, 3%,4%,5%), postive control (using peel off masks on the market). The Anova test results show a sig value of 0,000 or p<0,005 so it is concluded that the variabel has a difference. The conclusion of this study proves that the ethanol extract of green mustard leaves can be used as a peel-off mask for skin moisturizer, where the higher the concentration of mustard leaf extract, the higher the moisture vlue of the skin.

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Ridd, Matthew J., Kirsty Garfield, Daisy M. Gaunt, Sandra Hollinghurst, Niamh M. Redmond, Kingsley Powell, Victoria Wilson, et al. "Choice of Moisturiser for Eczema Treatment (COMET): feasibility study of a randomised controlled parallel group trial in children recruited from primary care." BMJ Open 6, no. 11 (November 2016): e012021. http://dx.doi.org/10.1136/bmjopen-2016-012021.

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Pedro, Adriana Orcesi, Achilles Machado Cruz, Lara Lopes Faco, Angélica Richart Csipak, Cassio Yooiti Yamakawa, and Vivienne Carduz Castilho. "New vaginal moisturizer is well-accepted and reduces symptoms related to the genitourinary syndrome of menopause in Brazilian women." Brazilian Journal of Health Review 5, no. 5 (October 10, 2022): 20418–31. http://dx.doi.org/10.34119/bjhrv5n5-211.

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Objectives: To evaluate the effectiveness and acceptability of a new vaginal moisturizer composed of a combination of humectants, moisturizers, bioadhesives, and viscosity polymers (sodium hyaluronate 0.1%, polycarbophil 1.5%, carbomer 1.5%, and glycerin 1%) for relief of vulvovaginal symptoms associated with genitourinary syndrome of menopause in Brazilian postmenopausal women. Methods: An open clinical trial was performed with 33 postmenopausal women between 47 and 68 years of age with genitourinary syndrome of menopause symptoms such as vaginal dryness accompanied by pain or discomfort during intercourse. Clinical efficacy in relieving symptoms of genitourinary syndrome of menopause and acceptability were assessed using a Likert scale questionnaire. Efficacy and safety were assessed through gynecological examination, which included visual inspection of the epithelium and vaginal contents, and determination of vaginal pH. Wilcoxon's non-parametric test and paired Student's t-test were used for statistical analyses.Results: After 3 weeks of treatment, most participants reported improvement in GSM symptoms like vaginal dryness (p<0.001), discomfort during or after sexual intercourse (p<0.001), pain during or after sexual intercourse (p<0.001), vaginal odor (p=0.047) and itching (p=0.032) and good acceptability of the moisturizer. There was no alteration in the vaginal health index; however, a reduction in vaginal inflammation (p=0.046) was observed. No clinically significant adverse events were reported by participants. Conclusions: Treatment with non-hormonal vaginal moisturizer for 3 consecutive weeks in postmenopausal women with symptoms of genitourinary syndrome of menopause promoted improvements in vaginal hydration, showing a clinically adequate profile of efficacy and safety, in addition to a satisfactory degree of acceptability.

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Ilham, Muhammad, and Kun Harismah. "Natural Moisturizer Based Formulation of Green Leaf Jelly (Cyclea Barbata Miers) with Bengkoang Addition (Pachyrhizus Erosus)." Jurnal Dedikasi 17, no. 1 (June 2, 2020): 11. http://dx.doi.org/10.22219/dedikasi.v17i1.12069.

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This study is aimed to know the use of green grass as a healthy alternative in preventing the occurrence of diseases caused by carcinogens and related to skincare. Sun exposure can cause various problems, especially on the skin, such as dry skin. Natural moisturizers can be the solution. Formulations of green grass jelly and bengkoang leaves can be an alternative use of natural moisturizers. One of the ingredients in green grass jelly leaves is the content of polyphenols and flavonoids contained in green grass jelly leaves can function as antioxidants. The research uses a draft of 2-Factor complete randomized design (RAL) type by using 4 treatment variations of green grass jelly formula (2.5%; 5%; 7.5%; and 10%) + Bengkoang (0%, 2.5%, 5%, 7.5%, 10%) and treatment of formulations without green grass. The results of the study are moisturizer based on green grass with the addition of bengkoang that has been made to meet the pH standard. Based on SNI-16-4399-1996, all samples that have been made meet the existing standards and the formulation samples that comply with the standard are F (D), ie green grass jelly concentration of 2.5% and Bengkong 5%

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Abraham, Anil, Anil Ganjoo, Sheilly Kapoor, Divya Sharma, and Abhay Talathi. "Practice pattern and use of a novel skin moisturizer containing skin barrier therapy in patients with atopic dermatitis: a cross-sectional survey among dermatologists in India." International Journal of Research in Dermatology 7, no. 5 (August 23, 2021): 663. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20213341.

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Background: Atopic dermatitis is considered as the most common chronic, inflammatory dermatological disorder. Skin barrier dysfunction represents an early pathology of this condition. Various factors contribute to development of such defects. Skin moisturizers remain the mainstay of therapy for AD along with other treatment modalities.Methods: Dermatologists across India were administered a questionnaire consisting of questions related to number of the patients seen with AD every week and their clinical experience regarding the use of novel skin moisturizer containing skin barrier therapy for the management of AD. The responses were analysed as number and percentages.Results: A total of 1605 patients were included in this survey. The complete responses were obtained from a total of 58 dermatologists. The majority (98%) of the dermatologists found the overall efficacy of novel skin moisturizer (Atoderm Intensive Baume) in AD patients as ‘satisfactory’. Atoderm Intensive Baume was found as efficacious in improving various parameters of AD such as skin dryness, severity of pruritus, inflammation, insomnia, itching, and urge to scratch. It was also well tolerated. It plays an important role in the repair of damaged skin barrier caused by AD.Conclusions: This survey findings indicated that novel skin moisturizer (Atoderm Intensive Baume) is a preferred formulation by dermatologists across India for the management of AD with proven efficacy and safety.

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Jacquet, Laureen, Daisy M. Gaunt, Kirsty Garfield, and Matthew J. Ridd. "Diagnosis, assessment, and treatment of childhood eczema in primary care: cross-sectional study." BJGP Open 1, no. 2 (May 2, 2017): bjgpopen17X100821. http://dx.doi.org/10.3399/bjgpopen17x100821.

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BackgroundThe majority of children with eczema in the UK are looked after in primary care yet we know little about their care in this setting.AimTo compare the diagnosis, assessment, and treatment of eczema in primary care with published diagnostic criteria and management guidelines.Design & settingCross-sectional study using data from a randomised controlled feasibility study. General practices, UK.MethodBaseline data from children aged 1 month to 5 years recruited ‘in-consultation’ for the Choice of Moisturiser in Eczema Treatment (COMET) feasibility study was used. These included clinician diagnosis and global severity assessment; the parent-completed Patient Orientated Eczema Measure (POEM); a questionnaire about eczema treatments, including use of topical corticosteroid (TCS); and, the Eczema Area Severity Index (EASI) carried out by trained researchers. Descriptive analyses were undertaken to compare diagnoses with UK diagnostic criteria, severity assessments, and treatment with the National Institute for Health and Care Excellent (NICE) guidance.ResultsData were available for 90 participants. Only 46% of participants labelled as having eczema met the UK diagnostic criteria. Agreement between the global severity assessment by a healthcare practitioner with the EASI and POEM measures of eczema severity were 44% and 48% respectively. Emollients and TCSs were underused with 44% of participants not using any emollient and 46% using one or more TCSs. The ‘match’ between eczema severity and TCSs potency was poor.ConclusionDiscrepancies were found between the diagnosis, assessment, and treatment of children with eczema in primary care, and UK diagnostic criteria and guidelines. Further investigation to explore the reasons for this discordance, and whether it matters, is needed.

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Tanner, Amanda E., Katherine A. Roof, Barry P. Katz, Adrian Katschke, J. Dennis Fortenberry, and Gregory D. Zimet. "A comparison of young women’s actual and assigned timing of use of a microbicide surrogate." Sexual Health 9, no. 4 (2012): 299. http://dx.doi.org/10.1071/sh11063.

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Purpose: This study examined young women’s actual timing of use of a microbicide surrogate gel (vaginal moisturiser (VM)) compared with assigned timing conditions. Methods: Participants used a VM with coitus during 4-week cycles over a 3-year period in random timing sequences: 1 h before coitus, 10 min before coitus and 10 min after coitus. Daily diaries collected information related to coital behaviours, VM use and timing, and participants’ and partners’ VM assessments. Descriptive and mixed-effects model analyses were conducted. Results: At least three VM timing conditions were completed by 109 women aged 18–22 years old. Of 17 772 diary days collected, coitus was reported on 2128 (1252 with VM use; 59%). Median times between VM application and coitus were: 60 min before coitus (mean = 68.2; s.d. = 76.9) for the 1-h pre-coital group, 13.5 min before coitus (mean = 44.9; s.d. = 117.1) for the 10-min pre-coital group and 5 min before coitus (mean = 24.5; s.d. = 205.1) for the 10-min post-coital group. Women reported that the VM was very easy to use (68%), it was somewhat messy (61%), they were very wet during sex (81%), sex was very good (80%) and their partners liked using the VM (38%). Conclusions: Overall, the VM was rated positively. There was substantial deviation in application time across timing conditions, with significantly greater variability in the post-coital group. These findings contribute to understanding of how VMs are accepted and used, with implications for HIV prevention with microbicides requiring specific application timing.

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Madsen, Steven, Kyla N. Price, Vivian Y. Shi, and Peter A. Lio. "Pearls in Mitigating Application Pain of Topical Nonsteroidal Agents." Dermatology 236, no. 5 (2020): 477–80. http://dx.doi.org/10.1159/000508771.

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Background: Topical steroid-sparing agents (SSA), such as tacrolimus, pimecrolimus, and crisaborole, represent an important therapeutic option in the treatment of inflammatory dermatoses such as atopic dermatitis. While these agents lack the common side effects associated with topical corticosteroids, they all share application site pain as an important adverse effect. Summary: Based on the available evidence and our experience, we suggest the following 7 practical strategies for decreasing the pain associated with SSA use. (1) Use a topical corticosteroid for a few days to reduce inflammation before starting the SSA treatment. (2) Use SSAs strategically. (3) Apply moisturizer before applying SSAs. (4) Store moisturizers in the refrigerator. (5) Ask the patient to apply the SSA on a small test area before broader application. (6) Apply the SSA on dry rather than on damp skin. (7) Consider using aspirin when appropriate for the patient.

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Gala, Monil Yogesh Neena, Snehal Sameer Muchhala, Sujeet Narayan Charugulla, Rahul Rathod, Amey Mane, Sucheta Pandit, Alok Ranjan Samal, and Anup Avijit Choudhury. "Evaluation of comedogenic potential of a moisturizer venusia max lotion (PAMA free)." IP Indian Journal of Clinical and Experimental Dermatology 8, no. 1 (March 15, 2022): 28–31. http://dx.doi.org/10.18231/j.ijced.2022.006.

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: Being commonly used skin care products, comedogenic potential of moisturizers should be assessed. : The aim of the study was to evaluate the comedogenic potential of a moisturizer Venusia Max Lotion (paraben-, alcohol-, mineral oil-, animal origin-(PAMA) free) when applied topically to the skin compared to the controls. : Double-blind, single-center, comparative study conducted at private institute in Mumbai, India: Approximately 0.025 gm of the test product and 0.025 ml of positive control (coconut oil) and negative control (glycerin) were applied and occluded under a patch on the upper back of healthy female participants. Patch application and removal were made 12 consecutive times on alternate days for each participant. On the last day, approximately 2 hours after patch removal, a follicular biopsy was taken for all participants on all product application zones. : Data analyzed with descriptive statistics using the SPSS software version 10.0.: Data from a total of 19 participants was analyzed. The mean age was 35.32 years. The mean comedone grade for Venusia Max Lotion (PAMA free) was significantly lower compared to the positive control (Coconut Oil) (1.00 vs. 2.11, respectively; P=.001). The mean comedone grade was 0.79 for negative control (Glycerine) which is nearly similar to that of the test product. The moisturizer product Venusia Max Lotion (PAMA free) is non-comedogenic as compared to positive control. Thus, it can be considered for moisturizing purposes without the fear of comedogenicity.

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Fitriani, Herlina Eva, Supriyono Eko Wardoyo, and Amry Syawaalz. "PENGARUH KONSENTRASI PEKTIN DALAM SUHU DAN WAKTU PENYIMPANAN BERBEDA TERHADAP KARAKTERISTIK PELEMBAB KULIT." Jurnal Sains Natural 4, no. 2 (December 3, 2017): 187. http://dx.doi.org/10.31938/jsn.v4i2.92.

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Effect of Concentration of Pectin in Different Temperature and Storage Time on Characteristics of Skin Moisturizing The use of pectin as a substituent a synthetic material in the manufacture of skin moisturizers can support the reuse of natural ingredients for skin care . This study aimed to obtain optimum concentrations in the preparation of skin moisturizers and to see the characteristics of skin moisturizer with the addition of the pectin concentration . The result showed the optimum concentration of pectin in the preparation of moisturizing the skin with a concentration of 0.05 % with a characteristic appearance ( viscosity ) was most preferably , the pH value of 7.08 ; a specific gravity of 0.98 g / ml ; viscosity of 2229 cP , emulsion stability of 100 % , and there was no microbial contamination in accordance with the standard of quality of skin moisturizersKeyword:. Pectin, concentration, characteristics, skin moisturizing ABSTRAK Penggunaan pektin sebagai pensubstitusi bahan sintetik dalam pembuatan pelembab kulit dapat mendukung penggunaan kembali bahan-bahan alami untuk perawatan kulit. Penelitian ini bertujuan untuk mendapatkan konsentrasi optimum dalam sediaan pelembab kulit dan mempelajari karakteristik pelembab kulit dengan penambahan konsentrasi pektin. Hasil penelitian didapatkan konsentrasi optimum pektin dalam sediaan pelembab kulit dengan konsentrasi 0,05 % dengan karakteristik penampakan (kekentalan) yang paling disukai, nilai pH 7,08; bobot jenis 0,98 g/ml; viskositas 2229 cP, stabilitas emulsi 100 %, dan tidak terdapat cemaran mikroba sesuai dengan syarat mutu pelembab kulit..Kata kunci: Pektin, konsentrasi, karakteristik, pelembab kulit

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Kwong, Cheong W., Giovanni Pellacani, Supenya Varothai, Ma L. Palmero, Srie Prihianti, Frances Tan, Leong K. Fon, et al. "Atopic dermatitis and role of Relizema: a multi-country user experience." International Journal of Research in Medical Sciences 10, no. 8 (July 27, 2022): 1747. http://dx.doi.org/10.18203/2320-6012.ijrms20221989.

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Atopic dermatitis (AD) is characterized by itching or pruritus, erythematous lesions, pruritus, and a skin barrier defect. Repeated scratching can trigger the itch-scratch cycle. Itching is associated with an adverse impact on quality of life. The first-line treatment of AD includes the use of topical corticosteroids for atopic dermatitis. However, parents of children with atopic dermatitis are often reluctant to accept the use of topical corticosteroids due to their concern of adverse effects flare-up. Relizema™ cream is a prescription emollient device (PED) multi-ingredients moisturizer formulation that has been indicated for the treatment of signs and symptoms of dermatitis. It is approved as medical device (MD) class IIa in Europe and it is registered as a topical medical device in countries of Asia Pacific. A consensus meeting of 9 dermatologists from multiple countries in Asia Pacific region treating atopic dermatitis was conducted. The dermatologists presented their cases of atopic dermatitis. PED was reported by patients to offer good relief of symptoms and improve skin softness unlike other moisturizers. In fact, a few patients reported relief with Relizema™ cream after using other moisturizers which were not demonstrating clinical effectiveness. Patients reported they noticed a softness in their skin after the application of the PED. PED was effective even in patients with lichenified skin. The formulation which is enriched with antioxidants helped relieve eczema. Due to its steroid-free formulation, the PED can be continued as a part of long-term maintenance treatment to maintain healthy skin conditions, prolong remission, and prevent recurrence.

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Kulthanan, Kanokvalai, Suphattra Trakanwittayarak, Papapit Tuchinda, Leena Chularojanamontri, Pichaya Limphoka, and Supenya Varothai. "A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population." BioMed Research International 2020 (October 16, 2020): 1–11. http://dx.doi.org/10.1155/2020/2857812.

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Many topical agents are available for treating the acute phase of acne; however, few agents have been proven beneficial during the maintenance phase. Objective. To evaluate the efficacy and safety of moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid during the maintenance phase of mild to moderate acne in Thai patients. Methods. One hundred and ten patients with mild to moderate acne vulgaris were initially treated with a fixed combination of adapalene 0.1%/benzoyl peroxide 2.5% gel once daily for 8 weeks. Fifty patients who achieved at least 50% reduction in lesion counts or at least a 2-grade improvement in the Investigator’s Global Assessment (IGA) grade from baseline were enrolled in the maintenance phase, which was an investigator-masked, left-right comparison, randomized, controlled, intraindividual study. Moisturizers with and without the active study ingredients were applied twice a day to each side of the face, respectively, for 12 weeks. Assessments included acne lesion counts, acne severity by IGA scoring, skin bioengineering measurements, and skin tolerability as assessed by both patient and physician. Results. The treatment group had a significant reduction in the mean counts of noninflammatory, inflammatory, and total lesions compared to the vehicle group at week 12 and also between baseline and week 12. There was no significant difference in the mean scores for skin dryness, stinging/burning, or pruritus at any time point between groups. Conclusions. Moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid reduced acne lesions and prevented the development of new lesions during the maintenance phase. This trial is registered with ClinicalTrials.gov registration no. NCT04002024.

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Desi, Eka, Ratna Djamil, and Faizatun Faizatun. "Body scrub containing Virgin Coconut Oil, coffee grounds (Coffea arabica Linn) and carbon active coconut shell (Activated carbon Cocos nucifera L) as a moisturiser and a skin brightener." Scripta Medica 52, no. 1 (2021): 76–81. http://dx.doi.org/10.5937/scriptamed52-30814.

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Introduction: Virgin Coconut Oil (VCO) contains a lot of medium chain fatty acids. VCO combined with coffee grounds (Coffea arabica Linn) and activated carbon (Activated carbon Cocos nucifera L) has the potential to form a preparation that can moisturise and brighten the skin. The purpose of this study was to make cosmetic cleansing preparations containing three natural ingredients. Methods: This study evaluated the organoleptic body scrub preparations, homogeneity, dispensability and pH for three different formulations. In vivo test for irritation (oedema and erythema) was carried out on albino rabbits (n = 3) for each treatment group. Clinical irritation testing was performed on the forearm of healthy volunteers, 17 - 45 years of age with no history of allergies (n = 30). Determination of skin moisture content and melanin index was carried out as a measure of effectiveness. Results: Organoleptic and homogeneity tests showed that preparations had dark black colour, the distinctive smell of coffee, it was homogeneous, spread ability was in the range of 4 cm with the pH at a safe pH for the skin. Irritation results also did not show any oedema and erythema in in vivo testing. In clinical testing no irritation occurred by testing the body scrub samples. Body scrubs routinely used by volunteers for 2 months increased moisture on the skin as well as brightness (p < 0.05). Conclusion: Body scrub creams containing VCO, coffee grounds and activated carbon are preparations that have the potential to be cosmetic cleansers.

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Natsir, Ramdhani M., and Lidya Natalia Sarira. "FORMULASI DAN EVALUASI SEDIAAN HAND MOISTURIZER GEL DARI GANDARIA." Media Kesehatan Politeknik Kesehatan Makassar 17, no. 2 (December 19, 2022): 265. http://dx.doi.org/10.32382/medkes.v17i2.2977.

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Salah satu tanaman obat yang berpotensi untuk dikembangkan khususnya di Indonesia bagian timur adalah buah gandaria. Buah gandaria yang terkandung selanjutnya dikembangkan lebih lanjut dalam bentuk sediaan topikal yaitu hand moisturizer gel. Hand moisturizer gel adalah sediaan semi padat yang terdiri dari suspensi yang dibuat dari partikel anorganik yang kecil atau molekul organik yang besar terpenetrasi oleh suatu cairan. Tujuan: Penelitian ini bertujuan untuk mengetahui proses formulasi sediaan hand moisturizer gel dari buah gandaria dan apakah dapat menghasilkan mutu fisik hand moisturizer gel yang sesuai dengan standar yang telah ditetapkan berdasarkan evaluasi uji organoleptik, uji homogenitas, uji iritasi, uji daya sebar, uji pH dan uji kelembaban. Metode : Penelitian ini merupakan penelitian eksperimental laboratorium. Buah gandaria dibuat sediaan hand moisturizer gel menjadi 4 formula dengan konsentrasi sediaan yang berbeda-masing. Evaluasi sediaan hand moisturizer gel antara lain pengamatan uji organoleptik, uji homogenitas, uji iritasi, uji daya sebar, uji pH dan uji kelembaban. Pada uji iritasi dan uji daya sebar dilakukan analisa statistik dengan metode One Way Anova. Hasil penelitian: Dari hasil parameter evaluasi sediaan hand moisturizer gel adalah sediaan hand moisturizer gel dengan konsentrasi 20 % merupakan sediaan yang paling baik karena yang paling memenuhi syarat uji sediaan hand moisturizer gel. Kesimpulan : Buah gandaria dapat diformulasikan sebagai sediaan hand moisturizer gel. Sediaan hand moisturizer gel yang paling baik terdapat pada konsentrasi 20 % berdasarkan evaluasi sediaan hand moisturizer gel.

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Deshmukh, Gaurav Anil, Dhiraj S. Dhoot, and Hanmant Barkate. "Clinical assessment of novel plant-based moisturizer “Elovera” in management of dry skin conditions." International Journal of Research in Dermatology 7, no. 6 (October 27, 2021): 771. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20214034.

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Background: Moisturizers are major component of basic daily skin care in patients with eczema/dermatitis. Botanical ingredients like aloe vera extract having anti-inflammatory property can be useful in reducing signs and symptoms along with improvement in dry skin in such patients.Methods: It was retrospective data analysis conducted across 145 centres in India. Patients with eczema/dermatitis who were prescribed Elovera a novel plant-based moisturizer were included in the study. Effectiveness was assessed by evaluating improvement in DASI score, physicians, and patients’ global assessment of disease. Safety was assessed by monitoring all the adverse events reported by the patients.Results: 402 patients were included in the study. There was significant improvement in mean baseline DASI score with with a reduction of 40.57% and 84.8% at week 2 and week 4, respectively. 86.31% (n=347) and 85.32% (n=343) patients reported significant improvement in their disease as per physician’s and patients’ global assessment of disease. Elovera was well tolerated and only 5 patients reported mild irritation and erythema during treatment.Conclusions: The result of our study proves that “Elovera” a novel plant-based moisturizer is associated with significant improvement in dry skin, signs, and symptoms of patients with eczema/dermatitis. Based on these results concomitant use of Elovera can be considered along with standard treatment for better outcome in patients with eczema/dermatitis.

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Hepni, Hepni. "FORMULASI SEDIAAN LOTION MENGGUNAKAN KOLAGEN TULANG IKAN PATIN (PANGASIUS SP) SEBAGAI PELEMBAB KULIT." Indonesian Trust Health Journal 4, no. 1 (April 30, 2021): 401–8. http://dx.doi.org/10.37104/ithj.v4i1.68.

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Background: In general, people consume catfish meat as a source of protein and a high content of omega 3, while the bones are disposed of as waste. Collagen is a protein derivative that has the effect of maintaining skin elasticity. Objective: To find out whether the catfish bone collagen can be formulated into lotions which in certain consentration can moisturize and do not irritate the skin. Method: Extraction of collagen from catfish bones, characterization of collagen by infrared spectrophotometry, making collagen lotion of catfish bones with a concentration of 1%, 1.5%, 2.5%, 3.5% and evaluation of collagen lotion preparations and test the ability of the preparation to moisturize. skin using a Skin moisturizer detector (SG- ed statistically using the ANOVA test with SPSS 20 Free trial. Result: Catfish bones contained collagen in waves of 3250-3350 cm-1 and 1260-1630 cm-1 which indicated the presence of amine and amide groups. The statistical test results show the probability is smaller than 0.05. The highest humidity was in the FE formula which contained 3.5% collagen with a moisture percentage of 53.0% with a level of "Moist" but lower than the lotions on the market with a percentage of 54.3%. Conclusion: Catfish bone collagen can be formulated into oil-in-water (M/A) emulsion type lotion. Abstrak Pendahuluan: Secara umum masyarakat mengkonsumsi daging ikan patin sebagai sumber protein dan kandungan omega 3 yang tinggi, sedangkan tulangnya dibuang sebagai limbah. Kolagen merupakan salah satu turunan protein yang mempunyai efek untuk mempertahankan kekenyalan kulit. Tujuan: Untuk mengetahui apakah kolagen tulang ikan patin dapat diformulasikan kedalam sediaan lotion yang dalam konsentrasi tertentu dapat melembabkan dan tidak mengiritasi kulit. Metode: Ekstraksi kolagen dari tulang ikan patin, karakterisasi kolagen dengan spektrofotometri inframerah, pembuatan lotion kolagen tulang ikan patin dengan konsentrasi 1%, 1,5%, 2,5%, 3,5% dan evaluasi sediaan lotion kolagen serta uji kemampuan sediaan melembabkan kulit memakai alat Skin moisturizer detector (SG-7D ) serta hasilnya diuji secara statistik memakai uji ANOVA dengan SPSS 20 Free trial. Hasil: Tulang ikan patin mengandung kolagen pada gelombang 32503350 cm-1 dan 1260-1630 cm-1 yang menunjukkan adanya gugus amina dan amida. Hasil uji statistik menunjukkan probabilitas lebih kecil dari 0,05. Kelembaban tertinggi yaitu pada formula FE yang mengandung 3,5% kolagen dengan persentase kelembaban 53,0% dengan level ”Lembab” tetapi lebih rendah dari lotion yang beredar dipasaran dengan persentase sebesar 54,3%. Kesimpulan: Kolagen tulang ikan patin dapat diformulasi menjadi sediaan lotion tipe emulsi minyak dalam air (M/A).

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Murakami, Mamoru, Yasuhiro Nishi, Kei Fujishima, Misaki Nishio, Yoko Minemoto, Takahito Kanie, and Masahiro Nishimura. "Impact of Types of Moisturizer and Humidity on the Residual Weight and Viscosity of Liquid and Gel Oral Moisturizers." Journal of Prosthodontics 25, no. 7 (September 16, 2015): 570–75. http://dx.doi.org/10.1111/jopr.12341.

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Carruthers, Jean, Gyasi Bourne, Michaela Bell, and Alan Widgerow. "Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer." Aesthetic Surgery Journal 41, no. 9 (April 2, 2021): NP1188—NP1198. http://dx.doi.org/10.1093/asj/sjab161.

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Abstract Background Over time human skin thins and loses elasticity; topical treatments attempt to reverse this process. Objectives The aim of this study was to assess the efficacy of TransFORM Body Treatment (TFB) in skin rejuvenation compared to a bland moisturizer on the extensor and volar forearms. Methods Blinded participants were given 2 products to apply on the designated forearms with follow-up at 4, 8, and 12 weeks. Measurements included skin thickness, photography, dermatopathology, cutaneous elasticity determined by 2 different methods, and patient-reported outcomes. All were compared to baseline. Results Changes between bland moisturizer and TFB were recorded for the following parameters. (1) Roughness: extensor –0.09 mm for bland moisturizer and –0.26 mm for TFB (P = 0.174); volar 0.01 mm for bland moisturizer and –0.23 mm for TFB (P = 0.004). (2) Recoil velocity: volar –56°/sec for bland moisturizer and –24°/sec for TFB (P = 0.61); extensor –95°/sec for bland moisturizer and –63°/sec for TFB (P = 0.57). Retraction speed: volar –3.25 ms for bland moisturizer and –20.08 ms for TFB (P = 0.33); extensor –2.17 ms for bland moisturizer and –10.83 ms for TFB (P = 0.66). Histologically, TFB resulted in an increase in mucopolysaccharide content, new collagen, and number of elastin fibers in the papillary dermis. Changes in the Rao-Goldman score were also observed: volar –0.17 for bland moisturizer and –0.33 for TFB (P = 0.25); extensor –0.08 for bland moisturizer and –0.17 for TFB (P = 0.36). Conclusions Histology showed production of new collagen and elastin. Quantification of changes in skin thickness, skin retraction speed, and skin recoil velocity showed trends that agree with the visual data. Level of Evidence: 4

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Rahim, Nur Izzati, Muhamad Helmi Husaini Rusmidi, and Khairul Adzfa Radzun. "The Development and User Acceptance Survey of Astaxanthin Infused Topical Moisturizer." Journal of Asian Scientific Research 12, no. 1 (April 1, 2022): 45–52. http://dx.doi.org/10.55493/5003.v12i1.4458.

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Astaxanthin was a beneficial carotenoid in the nutraceutical, food, cosmetics, and feed industries. The new astaxanthin infused topical moisturizer was developed using astaxanthin, Manuka honey, and Neutrogena Hydro Boost gel moisturizer. The astaxanthin was extracted from Haematococcus pluvialis subjected to the in-house astaxanthin extraction procedure developed by the Microalgae Research Laboratory, UiTM Puncak Alam, Selangor. Fifteen topical moisturizer samples were developed via Box-Behnken Design. The moisturizer properties were significantly influenced by astaxanthin, Neutrogena Hydro Boost gel moisturizer, and Manuka honey content based on the User Acceptance Survey done on 250 respondents. This study observed response surface regression, analysis of variance, and response optimization for appearance, aroma/smell, and texture. The optimum levels of the three factors were astaxanthin is at 1 ml, Neutrogena Hydro Boost gel moisturizer is at 20 ml, and Manuka honey must be less than 10 g which is at 0.9192g, as 69% of respondents like the composition.

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Garlina, Yossy Hanna. "Comparison of Skin Moisturizer: Consumer-Based Brand Equity (CBBE) Factors in Clusters Based on Consumer Ethnocentrism." Winners 15, no. 2 (September 30, 2014): 115. http://dx.doi.org/10.21512/tw.v15i2.625.

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This research aims to analyze relevant factors contributing to the four dimensions of consumer-based brand equity in skin moisturizer industry. It is then followed by the clustering of female consumers of skin moisturizer based on ethnocentrism and differentiating each cluster’s consumer-based brand equity dimensions towards a domestic skin moisturizer brand Mustika Ratu, skin moisturizer. Research used descriptive survey method analysis. Primary data was obtained through questionnaire distribution to 70 female respondents for factor analysis and 120 female respondents for cluster analysis and one way analysis of variance (ANOVA). This research employed factor analysis to obtain relevant factors contributing to the five dimensions of consumer-based brand equity in skin moisturizer industry. Cluster analysis and one way analysis of variance (ANOVA) were to see the difference of consumer-based brand equity between highly ethnocentric consumer and low ethnocentric consumer towards the same skin moisturizer domestic brand, Mustika Ratu skin moisturizer. Research found in all individual dimension analysis, all variable means and individual means show distinct difference between the high ethnocentric consumer and the low ethnocentric consumer. The low ethnocentric consumer cluster tends to be lower in mean score of Brand Loyalty, Perceived Quality, Brand Awareness, Brand Association, and Overall Brand Equity than the high ethnocentric consumer cluster. Research concludes consumer ethnocentrism is positively correlated with preferences towards domestic products and negatively correlated with foreign-made product preference. It is, then, highly ethnocentric consumers have positive perception towards domestic product.

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Tjandra, Oentarini, Linda J. Wijayadi, and Marcella E. Rumawas. "Green tea moisturizer improves skin hydration in elderly." Universa Medicina 37, no. 1 (February 8, 2018): 3. http://dx.doi.org/10.18051/univmed.2018.v37.3-12.

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BACKGROUND Dry skin is a major skin health problem in elderly. Green tea, which has an antioxidant effect, has recently been used as an active ingredient in moisturizing creams; yet the effect has not been well studied. This study compares the skin hydration effect of green tea and vitamin E moisturizer among elderly. METHODS This quasi-experimental study involved 60 elderly living in Tresna Werda Budi Mulia 4 Social Institution, Jakarta. Using the Runve HL 611 skin analyzer, skin capacitance was measured prior to experiment and every following week during the 5-week application of green tea and vitamin E skin moisturizer on both forearms. The consecutive measurement data was analyzed using Generalized Estimating Equation to compare the relative changes in skin hydration between the two moisturizer groups over 5 weeks of intervention. RESULTS The green tea moisturizer showed more significant increases in skin hydration level than the vitamin E moisturizer at all measurement sites on right arm and proximal left arm (p= 0.021), and medial and distal left arm (p= 0.034). Skin hydration levels significantly changed over time at proximal (p=0.021), medial (p=0.006) and distal (p=0.006) right arm, and medial left arm (p=0.021). A parallel trend of skin hydration improvements for both moisturizer groups indicated no correlation between the moisturizer type and the duration of usage (p >0.05) in all measurement locations. No side effects were observed during application period in both groups. CONCLUSION Routine use of moisturizer containing green tea may improve skin hydration in elderly.

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Chikin, V. V. "Topical methylprednisolone aceponate and dexpanthenol in the treatment of patients with atopic dermatitis." Vestnik dermatologii i venerologii 90, no. 5 (October 24, 2014): 112–16. http://dx.doi.org/10.25208/0042-4609-2014-90-5-112-116.

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The goals of the topical treatment of patients suffering from atopic dermatitis are suppression of the inflammatory reaction in the skin, elimination of itching, and recovery of the damaged protective lipid barrier of the epidermis. In this connection, topical glucocorticosteroids and skin moisturizers are used in the therapy of patients suffering from atopic dermatitis. Methylprednisolone aceponate (MPA, Advantan) being a topical glucocorticosteroid is characterized by high efficacy and safety. MPA is marked by the fast development of the therapeutic effect. This drug can be used for children older than 4 months and can be applied once a day. The availability of four dosage forms of MPA (emulsion, cream, ointment and fatty ointment) enables physicians to select a therapy with the use of this drug depending on the stage and localization of the skin lesion. Dexpanthenol (Bepanthen) being a tissue repair stimulator moisturizes the skin, protects the skin against an irritant effect, and restores the protective lipid barrier of the epidermis. The use of a combination of MPA being a topical glucocorticosteroid and dexpanthenol being a tissue repair stimulator can enhance the efficacy of the treatment of patients suffering from atopic dermatitis.

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Bakhri, Syamsul, Amirullah Amirullah, and Muhammad Ridha Kasim. "Pembuatan Sabun Cair Berbasis Minyak Kelapa Dengan Proses Saponifikasi Untuk Menghambat Pertumbuhan Bakteri Dengan Penambahan Minyak Zaitun (Pure Olive Oil) Untuk Pelembap Kulit." Jurnal Teknologi dan Industri Pertanian Indonesia 14, no. 1 (March 24, 2022): 34–38. http://dx.doi.org/10.17969/jtipi.v14i1.22567.

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This research was conducted to produce and determine liquid soap products that function as skin moisturizers and can inhibit microbial growth. In the process of making this liquid soap, two formulas are used, namely formula 1 which is made from coconut oil and alkali of KOH with the addition of olive oil and formula 2 which is made from coconut oil and alkali of KOH without the addition of olive oil . The manufacture of liquid soap in this study was carried out experimentally using the hot process method. Organoleptic testing with parameters of foam, skin dryness, and skin moisture was carried out using analytical observational and questionnaire methods involving fifteen correspondents. Testing the inhibition of microbial growth using Staphylococcus aureus bacteria contamination. The results obtained from this research are liquid soap formula 1 and formula 2 have a lot of foam and a very strong microbial growth retardant power, liquid soap formula 1 can moisturize the skin, and liquid soap formula 2 dries the skin. The results of this research, God willing, will be a reference for the author to continue this research to the stage of perfection and it is hoped that the results of this research can also be useful for the ummah and the nation in realizing a healthy life .

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Lane, Alfred T., and Sharon S. Drost. "Effects of Repeated Application of Emollient Cream to Premature Neonates' Skin." Pediatrics 92, no. 3 (September 1, 1993): 415–19. http://dx.doi.org/10.1542/peds.92.3.415.

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Objective. Emollient cream moisturizers are often used on premature newborns in neonatal intensive care units without accurate knowledge of the risks or benefits to the neonate. Design. We prospectively compared premature neonates treated with a water-in-oil emollient cream for up to 16 days to untreated premature neonates. Setting. The study was completed in a neonatal intensive care unit on neonates admitted for respiratory distress and/or possible sepsis. Patients. Thirty-four neonates, between 29 and 36 weeks estimated gestational age, entered the study. Interventions. One-half of the neonates were treated twice a day with an water-in-oil emollient cream, and the other half served as controls. Outcome Measures. The skin condition of the neonates' hands, feet, and abdomen was evaluated on entering the study and twice a week. Fungal cultures and quantitative bacterial cultures were obtained from the axilla and abdomen on entering the study and twice a week. Results. The mean gestational age of the treated neonates was 32.3 weeks, whereas the mean gestational age of the control neonates was 32.5 weeks. The neonates treated with emollient cream demonstrated statistically less dermatitis of their hands (day 2 through day 11), their feet (day 2 through day 16), and their abdomen (day 7 through day 11). Fungal cultures and quantitative bacterial cultures of the abdomen and axilla were equivalent in both groups. Conclusions. These studies document that emollient cream moisturizer therapy of premature neonates decreases dermatitis without changing the microbiological flora.

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Howard A., Epstein. "Anatomy of a Moisturizer." SKINmed: Dermatology for the Clinician 3, no. 5 (September 2004): 279–80. http://dx.doi.org/10.1111/j.1540-9740.2004.03392.x.

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46

Diana Draelos, Zoe. "THERAPEUTIC MOISTURIZERS." Dermatologic Clinics 18, no. 4 (October 2000): 597–607. http://dx.doi.org/10.1016/s0733-8635(05)70210-2.

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47

Albanova, Vera I., Olesya V. Kalinina, and Stanislava Yu Petrova. "The use of urea for skin barrier correction." Vestnik dermatologii i venerologii 98, no. 4 (September 19, 2022): 67–75. http://dx.doi.org/10.25208/vdv1329.

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The review summarizes information about the main causes and pathogenesis of xerosis cutis as one of the conditions indicating a violation of the epidermal barrier. Xerosis cutis is a clinical sign of a decrease in the amount and/or quality of lipids and/or hydrophilic substances in the stratum corneum of the epidermis. The modern approach to the treatment of dermatoses accompanied by violations of the epidermal barrier includes basic moisturizers. Urea not only moisturizes the skin. It is involved in the regulation of barrier function and antimicrobial protection. It is a low-molecular regulator of protein synthesis in keratinocytes, such as filaggrin, loricrin, involucrin and transglutaminase 1, cathelicidin, beta-defensin-2, water and urea carrier proteins into the cell, as well as proteins that promote the synthesis of intercellular matrix lipids. The main dermatotropic pharmacological effects of urea (hydration of the epidermis, strengthening of the barrier function of the skin, keratolytic effect, increased penetration of drugs into the skin) have been used in dermatological practice for many years. External agents with urea are used to treat skin diseases accompanied by dryness and excessive keratinization, to correct the deformation of nail plates of various genesis, to facilitate the local penetration of medicines. The use of topical UrocrEM5, UrocrEM10, Uroderm ointments containing 5%, 10% and 30% urea, respectively, is effective and safe.

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Sun, Changhong, Yipeng Cao, and Chen Liu. "Effects of moisturized inflow on compressor performance and aerodynamic noise." INTER-NOISE and NOISE-CON Congress and Conference Proceedings 263, no. 1 (August 1, 2021): 5467–74. http://dx.doi.org/10.3397/in-2021-3114.

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The effects of moisturized inflow on turbocharger compressor performance and aerodynamic noise were numerical analyzed in this paper. The gas-liquid two-phase flow method based on Euler-Lagrange model was firstly introduced. The influence of water concentration and water droplet diameter on compressor performance and internal flow characteristics at design speed were studied using the two-phase flow method. The compressor aerodynamic noise was also predicted at design condition under two different inflow conditions, including ideal inflow and moisturized inflow with 0.1% water concentration. The results indicate that moisturized inflow with an appropriate water concentration can reduce the outlet temperature of the compressor and improve the compressor performance, in which the water concentration is a dominant parameter. There is a phase transition process of water in the compressor with moisturized inflow, but moisturized inflow has little effects on the compressor internal flow characteristics. Moreover, the moisturized inflow also has influence on compressor aerodynamic noise.

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P, Apriyani, Yunahara Farida, and Faizatun. "Formulation and activity test of extract seaweed lip balm (sargassum binderi) and oil kenanga ( cananga oil ) as lip moisturizer." Research, Society and Development 10, no. 1 (January 31, 2021): e55210111935. http://dx.doi.org/10.33448/rsd-v10i1.11935.

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Cosmetics are preparations or combination of ingredients that ready to be used on the outside of body such as epidermis, hair, nails, lips, teeth and oral cavity. It has a function to clean, increase the attractiveness, change the appearance and protect it to keep the condition in a good state, improve body odor but not intended to cure a disease. The extraction method used to obtain seaweed extract is the maceration method using 96% ethanol solvent. The test method for hydration test uses TEWL within the Derma lab combo tool. Meanwhile, the hedonic test used 20 panelists to determine the level of suitability in lip balm preparations. This Research is about formulation and activity test of seaweed extract (Sargassum binderi) and sunflower oil kenaga (Cananga oil) as lip moisturizer. The purpose of this study was to utilize natural ingredients and determine the evaluation of lipbalm from seaweed and cananga flower oil which has a function to increase the moisture level of lip. The formulation of lipbalm was made by three concentrations, formulation 1, formulation 2 and formulation 3. Evaluation was done to test the skin irritation, skin hydration and hedonic test. The method of skin hydration helps to enhancer and moisture the skin by TEWL (transepodermal water loss) tool of derma lab combo. The result of this research showed that all the formulas does not irritate the skin, moisturize and preferred by the panelists. In the third formula, it has a result to increase the humidity of skin within the high significant differences among the three formulas.

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Rawlings, A. V., David A. Canestrari, and Brian Dobkowski. "Moisturizer technology versus clinical performance." Dermatologic Therapy 17, s1 (January 2004): 49–56. http://dx.doi.org/10.1111/j.1396-0296.2004.04s1006.x.

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