Дисертації з теми "MLT circulation"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся з топ-24 дисертацій для дослідження на тему "MLT circulation".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.
Muller, Lucas Omar. "Mathematical modelling and simulation of the human circulation with emphasis on the venous system: application to the CCSVI condition." Doctoral thesis, Università degli studi di Trento, 2014. https://hdl.handle.net/11572/367928.
Повний текст джерелаCarroll, Dustin. "Modeling Circulation Dynamics and Submarine Melt in Greenland Fjords." Thesis, University of Oregon, 2017. http://hdl.handle.net/1794/22626.
Повний текст джерелаShah, Ajay M. (Ajay Mukesh). "Technologies for the isolation of circulating tumor cells." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/72916.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (p. 125-129).
Metastasis, the spread and growth of tumor cells from the primary site to distant organs, is arguably the most devastating and deadly attribute of cancer, and is ultimately responsible for 90% of cancer-related deaths. Circulating tumor cells (CTCs) are exceedingly rare cells found in the whole blood of cancer patients which have the potential to serve as a 'blood biopsy'. The intricate characterization of these cells could result in an entire new class of therapies directly targeting metastasis. Present technologies enable only a susbset of potential analyses to be conducted, principally due to sub-optimal cell isolation sensitivity, purity, throughput, or handling method. Here, we present two novel technologies to address the challenge of CTC isolation. First, we build on affinity-based microfluidic cell capture platforms by developing sacrificial hydrogel coatings to enable the innocuous release of captured cells; we demonstrate that model CTCs captured from whole blood remain viable and proliferative following release and are compatible with downstream immunostaining and FISH analysis. Second, we present a novel cell sorting system that interrogates over 10 million individual events each second, resulting in a high throughput, ultra-efficient rare cell sorter that delivers enriched cells in a vial, readily compatible with virtually any downstream assay. This is the first system combining the high sensitivity and single cell resolution that is characteristic of FACS with the practicality of MACS at a throughput and specificity afforded by inertial focusing, enabling operation in both 'positive selection' and 'negative depletion' modes. We find greater than 90% cell isolation efficiencies with over 2.5 log depletion of contaminating WBCs. Furthermore, the system is applied to clinical patient samples, and proof-of-concept is demonstrated in a cohort of breast, lung and prostate patients. Working in a negative depletion mode to isolate target cells in an unbiased fashion, we used the system to assess single putative CTCs isolated from an endogenous pancreatic mouse model for gene expression of tumor markers. Initial data confirms CTC heterogeneity at the single cell level, and positions us to move forward with single cell transcriptome sequencing, which may reveal a broad array of CTC phenotypes including metastatic precursors.
by Ajay Mukesh Shah.
Ph.D.in Medical Engineering
Min, Changwook. "Miniaturized electromagnetic biosensors for circulating cancer biomarker detection." Thesis, Massachusetts Institute of Technology, 2017. http://hdl.handle.net/1721.1/113786.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (pages 113-120).
Cancer is one of leading cause of deaths, and responsible for 8.2 million deaths worldwide. Especially, 70% of deaths from cancer occur in low or mid income countries. In order to deliver affordable and accessible cancer care to low income developing countries, it is critical to develop rapid, low cost, and highly accurate tools for cancer detection and treatment. Recently, liquid biopsy and circulating cancer biomarkers such as circulating tumor cells (CTC), extracellular vesicles (EV), and cell free DNA (cfDNA) have gained great attentions for early diagnosis, prognosis, and treatment monitoring of cancer patients because they can be accessed in less invasive approaches through body fluids while providing quantitative information about original tumors at low cost. To facilitate detection of circulating cancer biomarkers, we developed electromagnetic biosensing systems for rapid and quantitative molecular analysis. First, we report portable nuclear magnetic resonance (NMR) system that detects cancer cells or proteins labelled with magnetic nanoparticles (MNPs). The developed NMR system could detect as low as 20 cancer cells in 5 uL samples. Second, we describe micro-Hall magnetometer that molecularly profiles single cancer cell with magnetic multiplexing. The micro-Hall magnetometer, which consisted of an array of 7 um x 7 um Hall sensors, showed its capability to differentiate magnetic particles with distinct magnetic moments. We applied this technology to molecular profiling of single ovarian cancer cell. Last, we introduce wirelessly powered electrochemical system that detect cancer specific EV and DNA. Using immuno-magnetic sandwich assay, we could enrich almost 100% of EVs from clinical specimens without ultracentrifugation and profile cancer specific transmembrane proteins from as low as 105 EVs. Also, we demonstrated PCR-free detection of single stranded DNA with in-vitro protein synthesis assay. These electromagnetic biosensors will be powerful tools to deliver more accessible and affordable cancer care to resource limited areas in developing countries.
by Changwook Min.
Ph. D. in Biomedical Engineering
Muller, Lucas Omar. "Mathematical modelling and simulation of the human circulation with emphasis on the venous system: application to the CCSVI condition." Doctoral thesis, University of Trento, 2014. http://eprints-phd.biblio.unitn.it/1184/1/Mueller_PhD.pdf.
Повний текст джерелаGörgen, Klaus. "Sensitivitätsstudien und Analyse von Atmosphäre-Meereis-Wechselwirkungen mit dem regionalen Atmosphärenmodell HIRHAM4 auf Basis eines neu entwickelten beobachtungsgestützten unteren Modellantriebs während ausgewählter Sommer über der Arktis, Laptewsee = Sensitivity studies and analysis of atmosphere-sea-ice-interactions with the regional atmospheric model HIRHAM4 using a newly developed observational lower boundary forcing dataset during selected summers over the Arctic/Laptev Sea /." Bremerhaven : Alfred-Wegener-Inst. für Polar- und Meeresforschung, 2006. http://www.gbv.de/dms/bs/toc/517265761.pdf.
Повний текст джерелаHuff, Russell. "Melt anomalies on the Greenland Ice Sheet and large scale modes of atmospheric circulation." Connect to online resource, 2007. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3256466.
Повний текст джерелаPersson, Marie, Christina Ekerfelt, Jan Ernerudh, Leif Matthiesen, Maria Jenmalm, Yvonne Jonsson, Martina Sandberg та Göran Berg. "Increased circulating paternal antigen-specific IFN-γ- and IL-4-secreting cells during pregnancy in allergic and non-allergic women". Linköpings universitet, Klinisk immunologi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-16134.
Повний текст джерелаPolanski, Stefan. "Simulation der indischen Monsunzirkulation mit dem Regionalen Klimamodell HIRHAM." Phd thesis, Universität Potsdam, 2011. http://opus.kobv.de/ubp/volltexte/2011/5250/.
Повний текст джерелаIn this study the regional climate model HIRHAM with a horizontal resolution of 50 km and 19 vertical levels is applied over the Asian continent to simulate the Indian monsoon circulation under present-day and past conditions. The integration domain extends from 0ºN - 50ºN and 42ºE - 110ºE and covers the high topography of Himalayas and Tibetan Plateau as well as the northern Indian Ocean. The main objective is the description of the regional coupling between monsoon circulation and orographic as well as thermal driving mechanisms of monsoon. A 44-years long simulation from 1958-2001, driven at the lateral and lower boundaries by European reanalysis (ERA40), is the basis for the validation of model results with observations based on station and gridded data sets. The focus is on the the long-term and decadal summer and winter monsoon climatology and its variability concerning atmospheric circulation, temperature and precipitation. The results successfully reproduce the observations due to a realistic simulation of topographic features. The simulated precipitation shows a better agreement with a high-resolution gridded data set over the central land areas of India and in the higher elevated Tibetan and Himalayan regions than ERA40. In different case and sensitivity studies the main driving mechanisms of the Indian monsoon (Sea Surface Temperatures, strength of the Siberian High in winter and soil moisture anomalies) are investigated. The results show, that the simulation of these mechanisms with a regional climate model is also difficult related to the complex non linear monsoon system and the small-scale processes, which are not just sufficiently parameterized and understood in the model. A paleoclimatic experiment for a 44-years long time slice in mid-holocene (6000 years before present), which is driven by a global ECHAM5 simulation, shows significant changes in the monsoon intensity due to the different solar forcing, which influences the SST, the circulation and the precipitation.
Dansereau, Véronique. "Ice shelf-ocean interactions in a general circulation model : melt-rate modulation due to mean flow and tidal currents." Thesis, Massachusetts Institute of Technology, 2012. http://hdl.handle.net/1721.1/78549.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (p. 121-123).
Interactions between the ocean circulation in sub-ice shelf cavities and the overlying ice shelf have received considerable attention in the context of observed changes in flow speeds of marine ice sheets around Antarctica. Modeling these interactions requires parameterizing the turbulent boundary layer processes to infer melt rates from the oceanic state at the ice-ocean interface. Here we explore two such parameterizations in the context of the MIT ocean general circulation model coupled to the z-coordinates ice shelf cavity model of Losch (2008). We investigate both idealized ice shelf cavity geometries as well as a realistic cavity under Pine Island Ice Shelf (PIIS), West Antarctica. Our starting point is a three-equation melt rate parameterization implemented by Losch (2008), which is based on the work of Hellmer and Olbers (1989). In this form, the transfer coefficients for calculating heat and freshwater fluxes are independent of frictional turbulence induced by the proximity of the moving ocean to the fixed ice interface. More recently, Holland and Jenkins (1999) have proposed a parameterization in which the transfer coefficients do depend on the ocean-induced turbulence and are directly coupled to the speed of currents in the ocean mixed layer underneath the ice shelf through a quadratic drag formulation and a bulk drag coefficient. The melt rate parameterization in the MITgcm is augmented to account for this velocity dependence. First, the effect of the augmented formulation is investigated in terms of its impact on melt rates as well as on its feedback on the wider sub-ice shelf circulation. We find that, over a wide range of drag coefficients, velocity-dependent melt rates are more strongly constrained by the distribution of mixed layer currents than by the temperature gradient between the shelf base and underlying ocean, as opposed to velocity-independent melt rates. This leads to large differences in melt rate patterns under PIIS when including versus not including the velocity dependence. In a second time, the modulating effects of tidal currents on melting at the base of PIIS are examined. We find that the temporal variability of velocity-dependent melt rates under tidal forcing is greater than that of velocity-independent melt rates. Our experiments suggest that because tidal currents under PIIS are weak and buoyancy fluxes are strong, tidal mixing is negligible and tidal rectification is restricted to very steep bathymetric features, such as the ice shelf front. Nonetheless, strong tidally-rectified currents at the ice shelf front significantly increase ablation rates there when the formulation of the transfer coefficients includes the velocity dependence. The enhanced melting then feedbacks positively on the rectified currents, which are susceptible to insulate the cavity interior from changes in open ocean conditions.
by Véronique Dansereau.
S.M.
Brand, Sascha. "Klimavariabilität der Tropo- und Stratosphäre in einem globalen gekoppelten Atmosphäre-Ozean-Modell mit vereinfachter stratosphärischer Chemie." Phd thesis, Universität Potsdam, 2007. http://opus.kobv.de/ubp/volltexte/2008/1660/.
Повний текст джерелаIn this work the atmospheric variability in a new coupled climate model (ECHO-GiSP) was analyzed, which includes a simplified stratospheric chemistry (up to 80 km height). Two simulations of 150 years were performed. In one of those simulations the atmospheric chemistry was modeled without having any influence back on the model dynamics. In the second simulation the impact of the chemistry on climate dynamics, taking place via the models radiation balance, was explicitly recognized. This is the first long term simulation using a fully coupled global climate model with interactive chemistry. The simulation with interactive chemistry shows a weakening of the Arctic Oscillation (AO) pattern of atmospheric variability. At the same time there is a reduction of the mean wind speeds in middle latitudes in the troposphere, which is caused by weaker temperature gradients between the tropics and the polar regions. Also, in the stratosphere a weakening and warming of the polar vortex is obvious. These effects of the coupling between atmospheric chemistry and the dynamics of the climate model are an important result, since in earlier climate simulations the variability of the AO often was overestimated. Due to the weakened polar vortex in the stratosphere also the large scale interhemispheric mean circulation is reduced. On the other hand, the tropospheric meridional mean circulation, and thus also the subtropical jetstreams of the zonal wind are enhanced. Furthermore there are tropical temperature variations in the troposphere and lower stratosphere, which are induced by stratospheric ozone variations associated to the phase of the AO. Generally, the coupling between tropo- and stratosphere is changed, which includes the vertical energy and momentum transfer by ascending planetary waves from the troposphere to the stratosphere.
Moura, Jos? Edson de. "Influ?ncia dos modelos digitais de terreno na modelagem de circula??o hidrodin?mica 2DH: um estudo de caso." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/15969.
Повний текст джерелаDigital Elevation Models (DEM) are numerical representations of a portion of the earth surface. Among several factors which affect the quality of a DEM, it should be emphasized the attention on the input data and the choice of the interpolating algorithm. On the other hand, several numerical models are used nowadays to characterize nearshore hydrodynamics and morphological changes in coastal areas, whose validation is based on field data collection. Independent on the complexity of the physical processes which are modeled, little attention has been given to the intrinsic bathymetric interpolation built within the numerical models of the specific application. Therefore, this study aims to investigate and to quantify the influence of the bathymetry, as obtained by a DEM, on the hydrodynamic circulation model at a coastal stretch, off the coast of the State of Rio Grande do Norte, Northeast Brazil. This coastal region is characterized by strong hydrodynamic and littoral processes, resulting in a very dynamic morphology with shallow coastal bathymetry. Important economic activities, such as oil exploitation and production, fisheries, salt ponds, shrimp farms and tourism, also bring impacts upon the local ecosystems and influence themselves the local hydrodynamics. This fact makes the region one of the most important for the development of the State, but also enhances the possibility of serious environmental accidents. As a hydrodynamic model, SisBaHiA? - Environmental Hydrodynamics System ( Sistema B?sico de Hidrodin?mica Ambiental ) was chosen, for it has been successfully employed at several locations along the Brazilian coast. This model was developed at the Coastal and Oceanographical Engineering Group of the Ocean Engineering Program at the Federal University of Rio de Janeiro. Several interpolating methods were tested for the construction of the DEM, namely Natural Neighbor, Kriging, Triangulation with Linear Interpolation, Inverse Distance to a Power, Nearest Neighbor, and Minimum Curvature, all implemented within the software Surfer?. The bathymetry which was used as reference for the DEM was obtained from nautical charts provided by the Brazilian Hydrographic Service of the Brazilian Navy and from a field survey conducted in 2005. Changes in flow velocity and free surface elevation were evaluated under three aspects: a spatial vision along three profiles perpendicular to the coast and one profile longitudinal to the coast as shown; a temporal vision from three central nodes of the grid during 30 days; a hodograph analysis of components of speed in U and V, by different tidal cycles. Small, but negligible, variations in sea surface elevation were identified. However, the differences in flow and direction of velocities were significant, depending on the DEM
Os modelos digitais de terreno (MDT) consistem na representa??o matem?tica computacional da distribui??o de um fen?meno espacial que ocorre dentro de uma regi?o da superf?cie terrestre. A qualidade da representa??o do MDT est? influenciada, dentre outros fatores, pela origem do dado e pelo algoritmo interpolador utilizado. A caracteriza??o da circula??o hidrodin?mica ? um dos estudos com apelo ambiental que se utiliza dos MDTs como dado de entrada e, independentemente da complexidade dos processos representados nos modelos num?ricos, pode ter a qualidade de seus resultados dependente da capacidade de reprodu??o do MDT usado para representar a batimetria da ?rea de interesse. Sendo assim, o objetivo deste estudo ? avaliar a influ?ncia de batimetrias obtidas de diversos MDTs, nos padr?es de circula??o hidrodin?mica via modelagem num?rica. Para tanto, considerou-se os dados referentes ? regi?o costeira do nordeste do Brasil, correspondente ao litoral setentrional do estado do Rio Grande do Norte, frontal aos munic?pios de Macau, Guamar? e Galinhos. Essa regi?o se caracteriza pela forte presen?a de processos f?sicos costeiros, com batimetria rasa e complexas fei??es de fundo. A presen?a intensa de atividades petrol?feras faz da regi?o uma das mais importantes para o desenvolvimento socioecon?mico do estado, mas, por outro lado, potencializa a possibilidade de acidentes ambientais de grandes e graves propor??es. O modelo de circula??o hidrodin?mica utilizado foi o 2DH, que faz parte do Sistema de Hidrodin?mica Ambiental, chamado SisBaHiA?, desenvolvido pela ?rea de Engenharia Costeira e Oceanogr?fica do Programa de Engenharia Oce?nica da COPPE/UFRJ. Os interpoladores avaliados foram Vizinho Natural, Krigagem, Triangula??o Irregular Linear, Inverso da Dist?ncia, Vizinho mais Pr?ximo, M?nima Curvatura, Fun??o de Base Radial, Polin?mio Local, Regress?o Polinomial, M?dia M?vel, M?trica de Dados e M?todo de Shepard Modificado, implementados no software comercial Surfer? para a gera??o dos MDTs. Os dados batim?tricos, que serviram como base para a constru??o dos MDTs, s?o oriundos de campanha de campo e de cartas n?uticas. Os resultados das modelagens foram analisados pelas avalia??es dos campos de velocidade e eleva??o, sob tr?s aspectos: uma vis?o espacial dos resultados, atrav?s da an?lise de tr?s perfis perpendiculares ? linha de costa e um perfil transversal ? linha de costa; uma vis?o temporal dos resultados, ao longo do per?odo de 30 dias, a partir de tr?s n?s centrais da malha; e finalmente uma an?lise hodogr?fica das componentes de velocidade em U e V, em diferentes ciclos de mar?s. Foram verificadas varia??es pouco significativas nos campos de eleva??es, podendo as mesmas serem desprezadas, por?m no que diz respeito aos campos de velocidade e dire??es de fluxo, notam-se varia??es associadas aos MDTs utilizados, uma vez que todas as condicionantes hidrodin?micas foram mantidas
Koch, Alexander. "Auswirkungen der koronaren Kollateralisierung bei Patienten mit akutem ST-Elevations-Myokardinfarkt und primärer perkutaner Koronarintervention." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-146666.
Повний текст джерелаMcMillan, Samuel. "Voortdurende verbetering : 'n noodsaaklikheid vir volgehoue groei van 'n gemeenskapskoerant met spesifieke verwysing na die publikasie - Paarl Post." Thesis, Stellenbosch : Stellenbosch University, 2000. http://hdl.handle.net/10019.1/52053.
Повний текст джерелаENGLISH ABSTRACT: The economic viability and continuity of any publication is determined by two critical factors, being: • The circulation of the publication, thus the readership, as well as • the advertising volumes of the publication. This particular study started by the realisation by management of the publication, Paarl Post, that these two critical factors had in real terms actually been declining since 1996, albeit marginally. The theme of continuous improvement was identified as critical in the process of eliminating "highs and lows", thus certain key areas had to be addressed. Furthermore these areas had to be continously evaluated and monitored. The process of change started with a process of gathering of information by means of questionnaires and personal interviews with certain key personnel by external consultants. A two-day session was scheduled where this information was processed with the help of the consultants and key personnel and the conclusion was made that the growth in circulation and advertising volumes and ultimately the growth in the publication was a function of certain key areas to be managed in the following way: • Cost efficient • Initiatives that lead to product growth • Optimizing of service • Continuous improvement of processes • Optimal use of manpower. The key areas of Marketing, Product, Communication, Processes and Information Technology were identified as key projects, which led to certain recommendations by these project teams based on abovementioned criteria. The "final" phase in the formal process, essentially a phase which never ends, is the implementation of the recommendations, and the continuous monitoring and following-up of the initiatives which ultimately develop to a continuous process of improvement, with the result: • Continuous circulation growth and • continous growth in advertising volumes, and ultimately continuous real growth in the community publication, Paarl Post.
AFRIKAANSE OPSOMMING: Enige publikasie se ekonomiese lewensvatbaarheid en kontinuïteit word deur twee kritieke faktore bepaal, naamlik: • Sirkulasie, m.a.w. die lesergetalle van die publikasie en • advertensievolumes Hierdie studie is gebore in die bestuur van die publikasie se waarneming dat hierdie twee aspekte van die gemeenskapskoerant, Paarl Post, sedert 1996 afneem in reële terme en dus die ekonomiese kontinuïteit van die publikasie bedreig. Die tema van voordurende verbetering is geïdentifiseer as krities in die totale proses ten einde "highs and lows" uit te skakel. Dus moes sekere sleutel-areas aangespreek word, maar hierdie areas moes verder ook deurlopend geëvalueer en gemonitor word. Die proses van verandering is begin deur 'n proses waarby eksterne konsultante betrek is om die eerste fase van die proses te fasiliteer in terme van die inwin van inligting deur middel van vraelyste en persoonlike onderhoude met sleutelpersoneel soos deur bestuur geïdentifiseer. 'n Tweedag sessie is geskeduleer waarby hierdie inligting met die hulp van die konsultante en die sleutelpersoneel deurgewerk is en die slotsom bereik is, dat groei in sirkulasie en advertensievolumes en dus uiteindelik die groei van die publikasie 'n funksie is van die mate waartoe sleutelareas van die Paarl Post as volg bestuur word: • Koste--effektief • Inisiatiewe wat tot produk-groei lei • Dienslewering optimaliseer • Voortdurende verbetering van prosesse • Optimale benutting van mannekrag. Die sleutelareas van Bemarking, Produk, Kommunikasie, Prosesse en Inligtingstegnologie is as projekte geïdentifiseer, waarvan die uiteinde is dat elke projekspan sekere aanbevelings moes doen aan die hand van bogenoemde kriteria. Die "laaste" stap in die formele proses, wat uiteindelik 'n stap is wat nooit eindig nie, is die implementering van die aanbevelings, asook die voordurende monitering en opvolging van die inisiatiewe wat uiteindelik ontwikkel in 'n deurlopende proses van verbetering, met die resultaat: • Volgehoue sirkulasiegroei, asook • volgehoue groei in advertensievolumes en uiteindelik voordurende reële groei van die gemeenskapspublikasie, Paarl Post.
Reichert, Bernhard K. "Quantification of natural climate variability in paleoclimatic proxy data using general circulation models : application to glacier systems = Quantifizierung der natürlichen Klimavariabilität in Paläoklimatischen Proxy-Daten mit Hilfe von Modellen der Allgemeinen Zirkulation : Anwendung auf Gletschersysteme /." [S.l. : s.n.], 2000. http://www.sub.uni-hamburg.de/disse/197/THESIS.PDF.
Повний текст джерелаBaquero, Bernal Astrid. "Interannual climate variability in the tropical Indian Ocean : a study with a hierarchy of coupled general circulation models = Interannuale Klimavariabilität im tropischen Indischen Ozean : eine Untersuchung mit einer Hierarchie von globalen gekoppelten Ozean-Atmosphären-Modellen /." Hamburg : Max-Planck-Institut für Meteorologie, 2004. http://mpimet.mpg.de/de/web/download.php?src=max_erdsystem&file=pdfupload&id=15&filename=BzE_8.pdf.
Повний текст джерелаLankhorst, Matthias [Verfasser]. "Analyses of the circulation in intermediate and shallow water masses of the North Atlantic with Lagrangian and profiling methods = Untersuchungen zur Zirkulation in mittleren und oberen Wassermassen des Nordatlantiks mit Lagrange'schen und profilierenden Methoden / Matthias Lankhorst." Kiel : Universitätsbibliothek Kiel, 2008. http://d-nb.info/1019543906/34.
Повний текст джерелаKan, Casina. "The role of Dysregulated Microrna in Ovarian Cancer." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10108.
Повний текст джерелаCastruccio, Frédéric. "Apports des données gravimétriques GRACE pour l'assimilation de données altimétriques et in-situ dans un modèle de l'Océan Pacifique Tropical." Phd thesis, Université Joseph Fourier (Grenoble), 2006. http://tel.archives-ouvertes.fr/tel-00138506.
Повний текст джерелаLes récentes avancées de notre connaissance du géoïde nous ont conduit à étudier l'impact de l'utilisation d'un signal altimétrique absolu. Un modèle (OPA) de l'Océan Pacifique Tropical, où des observations in-situ et quasi-synoptiques sont disponibles (réseau TAO), et un filtre de Kalman en rang réduit (SEEK) ont été mis au point et utilisés dans différentes configurations. La première suppose une situation pré-GRACE et utilise une MDT artificielle. La deuxième utilise une MDT observée déduite du géoïde GRACE. Conjointement à l'altimétrie, les profils de température TAO sont assimilés.
Ce travail montre l'importance d'une bonne référence pour les résidus altimétriques. Le résultat le plus important concerne la capacité du système d'assimilation utilisant GRACE à mieux composer avec des données mixtes: satellites et in-situ. Ici, l'assimilation conjointe d'altimétrie et de données TAO est plus performante grâce à la meilleure compatibilité des données.
En outre, une analyse physique, qui considère l'apport de l'assimilation à l'amélioration de la représentation de la dynamique du Pacifique Tropical, a été conduite. L'originalité de ce travail est de montrer comment l'assimilation contribue à améliorer notre compréhension des mécanismes physiques en action dans ce bassin.
De manière intéressante et rétrospective, cette analyse révèle aussi une zone (8°N) où les données GRACE semblent avoir des faiblesses qu'il serait judicieux de corriger.
Bou, Farah Mira. "Méthodes utilisant des fonctions de croyance pour la gestion des informations imparfaites dans les réseaux de véhicules." Thesis, Artois, 2014. http://www.theses.fr/2014ARTO0208/document.
Повний текст джерелаThe popularization of vehicles has created safety and environmental problems. Projects havebeen launched worldwide to improve road safety, reduce traffic congestion and bring more comfortto drivers. The vehicle network environment is dynamic and complex, sources are often heterogeneous,and therefore the exchanged information may be imperfect. The theory of belief functionsoffers flexibility in uncertainty modeling and provides rich tools for managing different types of imperfection.It is used to represent uncertainty, manage and fuse the various acquired information.We focus on the management of imperfect information exchanged between vehicles concerningevents on the road. The carried work distinguishes local events and spatial events, which do nothave the same characteristics. In an environment without infrastructure where each vehicle is afusion center and creates its own vision, the goal is to provide to each driver the synthesis of thesituation on the road as close as possible to the reality. Different models using belief functionsare proposed. Different strategies are considered: discount or reinforce towards the absence of theevent to take into account messages ageing, keep the original messages or just the fusion result invehicle database, consider the world update, manage the spatiality of traffic jam events by takinginto account neighborhood. Perspectives remain numerous; some are developed in the manuscriptas the generalization of proposed methods to all spatial events such as fog blankets
Moorman, Ruth. "Response of Antarctic ocean circulation to increased meltwater." Thesis, 2019. http://hdl.handle.net/1885/187134.
Повний текст джерелаVellinga, Michael. "Bifurcations and dynamics of the ocean's thermohaline circulation Vertakkingen en dynamica van de thermohaline oceaancirculatie : met een samenvatting in het Nederlands /." 1997. http://catalog.hathitrust.org/api/volumes/oclc/36712025.html.
Повний текст джерелаKoch, Alexander. "Auswirkungen der koronaren Kollateralisierung bei Patienten mit akutem ST-Elevations-Myokardinfarkt und primärer perkutaner Koronarintervention." Doctoral thesis, 2013. https://ul.qucosa.de/id/qucosa%3A12657.
Повний текст джерелаHillmann, Nadine. "Methodenvergleich zur Erfassung einer Restheparinisierung nach kardiochirurgischen Eingriffen mit Herz-Lungen-Maschine." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-002B-7CD3-9.
Повний текст джерела