Готові списки джерел за темами / MiRNA decoy

Добірка наукової літератури з теми "MiRNA decoy"

Автор: Grafiati
Опубліковано: 10 грудня 2022
Оновлено: 28 січня 2023

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Статті в журналах з теми "MiRNA decoy"

1

Shi, Tingting, Asahiro Morishita, Hideki Kobara, and Tsutomu Masaki. "The Role of Long Non-Coding RNA and microRNA Networks in Hepatocellular Carcinoma and Its Tumor Microenvironment." International Journal of Molecular Sciences 22, no. 19 (September 30, 2021): 10630. http://dx.doi.org/10.3390/ijms221910630.

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Hepatocellular carcinoma (HCC) is a common liver malignancy with high morbidity and poor prognosis. Long non-coding RNAs (lncRNAs) are involved in crucial biological processes of tumorigenesis and progression, and play four major regulatory roles, namely signal, decoy, guide, and scaffold, to regulate gene expression. Through these processes, lncRNAs can target microRNAs (miRNAs) to form lncRNA and miRNA networks, which regulate cancer cell proliferation, metastasis, drug resistance, and the tumor microenvironment. Here, we summarize the multifaceted functions of lncRNA and miRNA networks in the pathogenesis of HCC, the potential use of diagnostic or prognostic biomarkers, and novel therapeutic targets in HCC. This review also highlights the regulatory effects of lncRNA and miRNA networks in the tumor microenvironment of HCC.
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2

Zahm, Adam M., Calies Menard-Katcher, Alain J. Benitez, Daphne M. Tsoucas, Claire L. Le Guen, Nicholas J. Hand, and Joshua R. Friedman. "Pediatric eosinophilic esophagitis is associated with changes in esophageal microRNAs." American Journal of Physiology-Gastrointestinal and Liver Physiology 307, no. 8 (October 15, 2014): G803—G812. http://dx.doi.org/10.1152/ajpgi.00121.2014.

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The incidence of eosinophilic esophagitis (EoE) has increased in the past several years, yet our understanding of its pathogenesis remains limited. To test the hypothesis that microRNAs (miRNAs) are altered in children with EoE, miRNAs were profiled in esophageal mucosa biopsies obtained from patients with active disease ( n = 5) and healthy control subjects ( n = 6). Fourteen miRNAs were significantly altered between groups; four of these miRNAs were decreased in EoE patients. A panel of five miRNAs (miR-203, miR-375, miR-21, miR-223, and miR-142-3p) were selected for validation in an independent set of samples from control ( n = 22), active disease ( n = 22), inactive disease ( n = 22), and gastroesophageal reflux disease ( n = 6) patients. Each panel miRNA was significantly altered among groups. miRNA changes in esophageal biopsies were not reflected in the circulating RNA pool, as no differences in panel miRNA levels were observed in sera collected from the four patient groups. In addition, in contrast to previous studies, no change in esophageal miRNA levels was detected following treatment that resolved esophageal eosinophilia. In an effort to identify the ramifications of reduced esophageal miR-203, miR-203 activity was inhibited in cultured epithelial cells via expression of a tough decoy miRNA inhibitor. Luciferase reporter assays demonstrated that miR-203 does not directly regulate human IL-15 through targeting of the IL-15 3′-untranslated region. From these experiments, it is concluded that miRNAs are perturbed in the esophageal mucosa, but not the serum, of pediatric EoE patients. Further investigation is required to decipher pathologically relevant consequences of miRNA perturbation in this context.
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3

Wang, Danyang, Huanhuan Tang, Xinhui Xu, Wei Dai, Jian Wu та Jinke Wang. "Control the intracellular NF-κB activity by a sensor consisting of miRNA and decoy". International Journal of Biochemistry & Cell Biology 95 (лютий 2018): 43–52. http://dx.doi.org/10.1016/j.biocel.2017.12.009.

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4

Nigi, Laura, Giuseppina Grieco, Giuliana Ventriglia, Noemi Brusco, Francesca Mancarella, Caterina Formichi, Francesco Dotta, and Guido Sebastiani. "MicroRNAs as Regulators of Insulin Signaling: Research Updates and Potential Therapeutic Perspectives in Type 2 Diabetes." International Journal of Molecular Sciences 19, no. 12 (November 22, 2018): 3705. http://dx.doi.org/10.3390/ijms19123705.

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The insulin signaling pathway is composed of a large number of molecules that positively or negatively modulate insulin specific signal transduction following its binding to the cognate receptor. Given the importance of the final effects of insulin signal transduction, it is conceivable that many regulators are needed in order to tightly control the metabolic or proliferative functional outputs. MicroRNAs (miRNAs) are small non-coding RNA molecules that negatively modulate gene expression through their specific binding within the 3′UTR sequence of messenger RNA (mRNA), thus causing mRNA decoy or translational inhibition. In the last decade, miRNAs have been addressed as pivotal cellular rheostats which control many fundamental signaling pathways, including insulin signal transduction. Several studies demonstrated that multiple alterations of miRNAs expression or function are relevant for the development of insulin resistance in type 2 diabetes (T2D); such alterations have been highlighted in multiple insulin target organs including liver, muscles, and adipose tissue. Indirectly, miRNAs have been identified as modulators of inflammation-derived insulin resistance, by controlling/tuning the activity of innate immune cells in insulin target tissues. Here, we review main findings on miRNA functions as modulators of insulin signaling in physiologic- or in T2D insulin resistance- status. Additionally, we report the latest hypotheses of prospective therapies involving miRNAs as potential targets for future drugs in T2D.
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5

Qiu, Huiling, Jiasheng Zhong, Lan Luo, Nian Liu, Kang Kang, Junle Qu, Wenda Peng, and Deming Gou. "A PCR-Based Method to Construct Lentiviral Vector Expressing Double Tough Decoy for miRNA Inhibition." PLOS ONE 10, no. 12 (December 1, 2015): e0143864. http://dx.doi.org/10.1371/journal.pone.0143864.

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6

Chen, Liming, Yifan Bao, Suzhen Jiang та Xiao-bo Zhong. "The Roles of Long Noncoding RNAs HNF1α-AS1 and HNF4α-AS1 in Drug Metabolism and Human Diseases". Non-Coding RNA 6, № 2 (24 червня 2020): 24. http://dx.doi.org/10.3390/ncrna6020024.

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Long noncoding RNAs (lncRNAs) are RNAs with a length of over 200 nucleotides that do not have protein-coding abilities. Recent studies suggest that lncRNAs are highly involved in physiological functions and diseases. lncRNAs HNF1α-AS1 and HNF4α-AS1 are transcripts of lncRNA genes HNF1α-AS1 and HNF4α-AS1, which are antisense lncRNA genes located in the neighborhood regions of the transcription factor (TF) genes HNF1α and HNF4α, respectively. HNF1α-AS1 and HNF4α-AS1 have been reported to be involved in several important functions in human physiological activities and diseases. In the liver, HNF1α-AS1 and HNF4α-AS1 regulate the expression and function of several drug-metabolizing cytochrome P450 (P450) enzymes, which also further impact P450-mediated drug metabolism and drug toxicity. In addition, HNF1α-AS1 and HNF4α-AS1 also play important roles in the tumorigenesis, progression, invasion, and treatment outcome of several cancers. Through interacting with different molecules, including miRNAs and proteins, HNF1α-AS1 and HNF4α-AS1 can regulate their target genes in several different mechanisms including miRNA sponge, decoy, or scaffold. The purpose of the current review is to summarize the identified functions and mechanisms of HNF1α-AS1 and HNF4α-AS1 and to discuss the future directions of research of these two lncRNAs.
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7

López-Luis, Mario Ángel, Cristian Julio César Padrón-Manrique, Jesús Alberto García-Lerena, Daniela Lozano-Amado, Rosaura Hernández-Rivas, Odila Saucedo-Cárdenas, Alfonso Méndez-Tenorio, and Jesús Valdés. "In Silico Identification and Characterization of circRNAs as Potential Virulence-Related miRNA/siRNA Sponges from Entamoeba histolytica and Encystment-Related circRNAs from Entamoeba invadens." Non-Coding RNA 8, no. 5 (September 26, 2022): 65. http://dx.doi.org/10.3390/ncrna8050065.

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Ubiquitous eukaryotic non-coding circular RNAs regulate transcription and translation. We have reported full-length intronic circular RNAs (flicRNAs) in Entamoeba histolytica with esterified 3′ss and 5′ss. Their 5′ss GU-rich elements are essential for their biogenesis and their suggested role in transcription regulation. Here, we explored whether exonic, exonic-intronic, and intergenic circular RNAs are also part of the E. histolytica and E. invadens ncRNA RNAome and investigated their possible functions. Available RNA-Seq libraries were analyzed with the CIRI-full software in search of circular exonic RNAs (circRNAs). The robustness of the analyses was validated using synthetic decoy sequences with bona fide back splice junctions. Differentially expressed (DE) circRNAs, between the virulent HM1:IMSS and the nonvirulent Rahman E. histolytica strains, were identified, and their miRNA sponging potential was analyzed using the intaRNA software. Respectively, 188 and 605 reverse overlapped circRNAs from E. invadens and E. histolytica were identified. The sequence composition of the circRNAs was mostly exonic although different to human circRNAs in other attributes. 416 circRNAs from E. histolytica were virulent-specific and 267 were nonvirulent-specific. Out of the common circRNAs, 32 were DE between strains. Finally, we predicted that 8 of the DE circRNAs could function as sponges of the bioinformatically reported miRNAs in E. histolytica, whose functions are still unknown. Our results extend the E. histolytica RNAome and allow us to devise a hypothesis to test circRNAs/miRNAs/siRNAs interactions in determining the virulent/nonvirulent phenotypes and to explore other regulatory mechanisms during amoebic encystment.
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8

de Vasconcellos, Jaira F., Colleen Byrnes, Y. Terry Lee, Megha Kaushal, Joshua M. Allwardt, Antoinette Rabel, and Jeffery L. Miller. "Targeted Reduction of Let-7a miRNA Increases Fetal Hemoglobin in Human Adult Erythroblasts." Blood 124, no. 21 (December 6, 2014): 451. http://dx.doi.org/10.1182/blood.v124.21.451.451.

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Abstract MicroRNAs (miRNAs) are a class of small, noncoding RNAs that bind and regulate target messenger RNAs (mRNAs). The let-7 family consists of twelve genes encoding nine highly conserved miRNAs that are involved in developmental timing events in multicellular organisms. Previous studies showed regulation during the fetal-to-adult transition in the erythroid lineage with significant increases in let-7 miRNAs from adult compared to umbilical cord blood reticulocytes (1). Further studies indicated that reduced expression of let-7 in adult CD34+ cells by “sponge” targeting the miRNA family seed region caused increased fetal hemoglobin (HbF), but the mean level of HbF remained less than 20% of the total hemoglobin (2). Increased expression of LIN28A (a major regulator of all let-7 miRNAs) caused greater increases in HbF (greater than 30% of the total) in cultured erythrocytes from pediatric patients with HbSS genotype (3). However, these studies did not address the potential for targeting an individual let-7 miRNA family member to regulate HbF expression. For this purpose, we initially determined the expression levels of mature let-7 family members in purified cell populations sorted from peripheral blood. The total levels of let-7 miRNAs in peripheral blood cells were as follows: reticulocytes: 1.7E+08 ± 1.0E+08 copies/ng; neutrophils: 2.0E+07 ± 1.1E+07 copies/ng; lymphocytes: 1.1E+07 ± 6.2E+06 copies/ng and monocytes: 3.5E+06 ± 2.7E+06 copies/ng. Among the individual species, let-7a was identified as a predominantly expressed let-7 family member in reticulocytes. As such, we hypothesized that specifically targeting let-7a may be sufficient to regulate HbF levels. To study the effects of let-7a miRNAs upon erythropoiesis and globin expression, a lentiviral construct that incorporated the tough decoy (TuD) design to target let-7a was compared with empty vector controls. Transductions were performed in CD34+ cells from five adult healthy volunteers cultivated ex vivo in erythropoietin-supplemented serum-free media for 21 days. Down-regulation of let-7a was confirmed by Q-RT-PCR at day 14 (control: 1.4E+07 ± 2.4E+06 copies/ng; let-7a-TuD: 1.6E+06 ± 4.6E+05 copies/ng; p=0.0003). Cell proliferation and differentiation were comparable in let-7a-TuD versus control transductions. Expression levels of globin genes were evaluated upon let-7a-TuD by Q-RT-PCR. Let-7a-TuD transductions caused significantly increased gamma-globin mRNA expression levels compared to control transductions (control: 1.2E+06 ± 6.8E+05 copies/ng; let-7a-TuD: 1.1E+07 ± 4.5E+06 copies/ng; p=0.004). HPLC analyses at the end of the culture period demonstrated robust increases in HbF levels after let-7a-TuD transduction (HbF control: 4.7 ± 0.6%; let-7a-TuD: 38.2 ± 3.8%; p=0.00003). In addition, the expression patterns of the erythroid transcription factors BCL11A, KLF1 and SOX6 were investigated. Let-7a-TuD decreased BCL11A mRNA expression levels (control: 1.7E+03 ± 4.5E+02 copies/ng; let-7a-TuD: 4.3E+02 ± 1.8E+02 copies/ng; p=0.003), but major changes in KLF1 or SOX6 were not detected. In summary, we report here that the let-7 miRNA family is differentially expressed in purified cell populations from adult human blood, and that let-7a is a predominantly expressed species in reticulocytes. Further, targeted reduction of let-7a in erythroblasts is sufficient to cause robust increases in gamma-globin mRNA expression and HbF to mean levels around 35-40% of the total hemoglobin produced. Targeting of individual let-7 genes or RNA transcripts may be useful for therapeutic induction of HbF expression in patients with sickle cell disease or other beta-hemoglobinopathies. 1) Noh SJ et al. J Transl Med. 7:98 (2009). 2) Lee YT et al. Blood. 122:1034-41 (2013). 3) Vasconcellos JF et al. Blood. 122: Abstract 313 (2013). Disclosures No relevant conflicts of interest to declare.
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9

Ko, Nai-Yu, Li-Ru Chen, and Kuo-Hu Chen. "The Role of Micro RNA and Long-Non-Coding RNA in Osteoporosis." International Journal of Molecular Sciences 21, no. 14 (July 10, 2020): 4886. http://dx.doi.org/10.3390/ijms21144886.

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Osteoporosis is a major concern worldwide and can be attributed to an imbalance between osteoblastic bone formation and osteoclastic bone resorption due to the natural aging process. Heritable factors account for 60–80% of optimal bone mineralization; however, the finer details of pathogenesis remain to be elucidated. Micro RNA (miRNA) and long-non-coding RNA (lncRNA) are two targets that have recently come into the spotlight due to their ability to control gene expression at the post-transcriptional level and provide epigenetic modification. miRNAs are a class of non-coding RNAs that are approximately 18–25 nucleotides long. It is thought that up to 60% of human protein-coding genes may be regulated by miRNAs. They have been found to regulate gene expression that controls osteoblast-dependent bone formation and osteoclast-related bone remodeling. lncRNAs are highly structured RNA transcripts longer than 200 nucleotides that do not translate into proteins. They have very complex secondary and tertiary structures and the same degradation processes as messenger RNAs. The fact that they have a rapid turnover is due to their sponge function in binding the miRNAs that lead to a degradation of the lncRNA itself. They can act as signaling, decoy, and framework molecules, or as primers. Current evidence suggests that lncRNAs can act as chromatin and transcriptional as well as post-transcriptional regulators. With regards to osteoporosis, lncRNA is thought to be involved in the proliferation, apoptosis, and inflammatory response of the bone. This review, which is based on a systematic appraisal of the current literature, provides current molecular and genetic opinions on the roles of miRNAs and lncRNAs in osteoporosis. Further research into the epigenetic modification and the regulatory roles of these molecules will bring us closer to potential disease-modifying treatment for osteoporosis. However, more issues regarding the detailed actions of miRNAs and lncRNAs in osteoporosis remain unknown and controversial and warrant future investigation.
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Li, Rongpeng, Lizhu Fang, Qinqin Pu, Huimin Bu, Pengcheng Zhu, Zihan Chen, Min Yu та ін. "MEG3-4 is a miRNA decoy that regulates IL-1β abundance to initiate and then limit inflammation to prevent sepsis during lung infection". Science Signaling 11, № 536 (26 червня 2018): eaao2387. http://dx.doi.org/10.1126/scisignal.aao2387.

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Більше джерел

Дисертації з теми "MiRNA decoy"

1

Trinh, Tat To. "REGULATION OF DROSOPHILA mRNA STABILITY BY DEADENYLATION ELEMENTS AND miRNAs." Case Western Reserve University School of Graduate Studies / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=case1436441986.

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2

Werneck, Renata Iani. "Complex segregation analysis of dental decay in an isolated population from North of Brazil / Renata Iani Werneck ; supervisor, Marcelo Távora Mira : co-supervisora, Paula Cristina Trevilatto." reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2010. http://www.biblioteca.pucpr.br/tede/tde_busca/arquivo.php?codArquivo=2014.

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Анотація:
Tese (doutorado) - Pontifícia Universidade Católica do Paraná, Curitiba, 2010
Bibliografia: f. [72], 81
A cárie dentária é uma doença crônica, complexa e uma das enfermidades mais comuns na Odontologia. É amplamente aceito que a ocorrência da cárie depende de fatores ambientais e fatores relacionados com o hospedeiro, como dieta, susceptibilidade do indivíd
Dental decay is a chronic, complex disease and one of the most common diseases in the population. It is widely accepted that the occurrence of dental decay depends on environmental and host-related factors, such as diet, biofilm composition, host suscepti
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3

Navickas, Albertas. "Cytoplasmic control of sense-antisense mRNA pairs in Saccharomyces cerevisiae." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066381/document.

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Les récentes études transcriptomiques chez divers organismes ont montré que la transcription des gènes convergents peut produire des ARN messagers (ARNm) chevauchants. Ce phénomène a été analysé dans le contexte de l’interférence par ARN (ARNi) nucléaire, et peu d’information existe quant au destin cytoplasmique des messagers 3’ chevauchants ou leur impact sur l’expression des gènes. Dans ce travail, nous avons abordé les conséquences potentielles de l’interaction entre des paires d’ARNm sens-antisens chez Saccharomyces cerevisiae, un organisme modèle naturellement dépourvu de l’ARNi. Nous avons démontré que les extrémités 3’ complémentaires des ARNm peuvent interagir dans le cytoplasme et moduler la stabilité ainsi que la traduction d’ARNm. Nos résultats sont issus d’une étude détaillée d’une paire d’ARNm convergents, POR1 et OCA2, ensuite généralisée par l’approche de l’ARNi reconstituée chez S. cerevisiae. L’analyse globale a confirmé que dans les cellules sauvages, les paires d’ARNm sens-antisens forment des duplexes d’ARN in vivo et ont un rôle potentiel à moduler l’expression d’ARNm ou de protéines respectifs, dans des différentes conditions de croissance. Nous avons montré que le destin de centaines des messagers convergents est contrôlé par Xrn1, révélant l’importance de cette exoribonucléase 5’-3’ cytoplasmique très conservée dans la régulation post-transcriptionnelle des gènes convergents. Notre travail ouvre donc la perspective de considérer un nouveau mécanisme de l’interaction entre les paires d’ARNm sens-antisens dans le cytoplasme, chez les organismes contenant ou non la voie de l’interférence par ARN
Recent transcriptome analyses have revealed that convergent gene transcription can produce many 3’ overlapping mRNAs in diverse organisms. This phenomenon has been studied in the context of nuclear RNA interference (RNAi) pathway, however little is known about the cytoplasmic fate of 3’ overlapping messengers or their impact on gene expression. In this work, we address the outcomes of interaction between sense-antisense mRNA pairs in Saccharomyces cerevisiae, a model organism naturally devoid of RNAi. We demonstrate that the complementary tails of 3’ overlapping mRNAs can interact in the cytoplasm in a sequence-specific manner and promote post-transcriptional remodeling of mRNA stability and translation. Our findings are based on the detailed analysis of a convergent mRNA pair, POR1 and OCA2, subsequently generalized using the reconstituted RNAi approach in S. cerevisiae. Genome-wide experiments confirm that in wild-type cells, sense-antisense mRNA pairs form RNA duplexes in vivo and thus have potential roles in modulating the respective mRNA or protein levels under different growth conditions. We show that the fate of hundreds of messenger-interacting messengers is controlled by Xrn1, revealing the extent to which this conserved 5’-3’ cytoplasmic exoribonuclease plays an unexpected but key role in the post-transcriptional control of convergent gene expression. In sum, our work opens a perspective to consider an additional, cytoplasmic mechanism of interaction between sense-antisense mRNA pairs, in both RNAi-positive and negative organisms
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4

Li, Yanjiao. "Functional analysis of conserved microRNAs in Arabidopsis thaliana." Phd thesis, 2015. http://hdl.handle.net/1885/16369.

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MicroRNAs (miRNAs) are non-coding RNAs of approximately 21 nucleotides that negatively regulate gene expression. In plants, many miRNAs target key regulatory genes, such as transcription factors, which play critical roles in plant developmental processes and stress responses. Underscoring their importance, many of these miRNA-target relationships are highly conserved, such as the miR159-MYB regulatory module that appears present in all land plants. This regulatory relationship has been extensively studied in Arabidopsis. In seeds and flowers, where miR159 activity is weak, MYB activity promotes programmed cell death (PCD), facilitating seed germination and anther development respectively. Moreover, the generation of a loss-of-function mir159 mutant has been shown to result in pleiotropic vegetative defects (e.g. curled/rounded leaves and stunted growth), indicating a critical role of miR159 in controlling rosette development. However, what the funcational role of this regulatory module in rosettes remains unknown. Via transcript analysis, I found that miR159 was strongly and ubiquitously expressed throughout the rosette development, where it appeared to constitutively silence MYB activity, suggesting the miR159-MYB module is not developmentally responsive. However, constant miR159 activity is required for normal rosette growth, as an inducible inhibition of miR159 resulted in morphological abnormalities of the rosette. This led to the hypothesis that miR159 could be stress responsive, where if repressed under a particular condition this would enable MYB expression. However, under what environmental condition this occurs remains unclear, because miR159 silencing was found to be extremely robust: neither biotic stresses known to inhibit miRNA activity (a virus containing a silencing suppressor), nor a range of abiotic stresses was able to inhibit miR159 function sufficiently to activate MYB-related phenotypic defects. As a complementary approach to gain insights into the function of the MYB33/65 pathway, an ethyl methanesulfonate (EMS) mutagenesis screen of mir159 suppressor was undertaken. Interestingly, a high frequency of mir159 revertants was obtained, in which MYB expression was attenuated, suggesting the existence of multiple regulators of MYB expression, and that possibly the miR159-MYB module is extensively networked. The eventual identification of these repressor alleles may shed light on function of the miR159-MYB module in rosettes. Owing to the fact that most miRNAs belong to multigene families, to which traditional loss-of-function approaches cannot be applied due to genetic redundancy, the transgenic approach of using miRNA "SPONGEs (SPs)" was explored to determine their ability in generating loss-of-function mirna outcomes. SPs are transgenes that harbor multiple target sites complementary to miRNAs, leading to their sequestration, an approach that has been effective in animal systems, but not tested in plants. Here, ten miRNA SPs were designed to target different conserved plant miRNA families. Their efficacies in inhibiting the respective miRNAs varied dramatically, where some SPs induced a strong loss-of-function outcome, whereas others did not. What underpins this variability is unclear; neither SP expression level, the free energy (ΔG) of the miRNA-SP interaction or the predicted target accessibility correlated with inhibition efficacies. This likely highlights the complexity of miRNA-target interactions and that when a SP cannot induce any obvious phenotypic impact, alternative approaches will be required.
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Частини книг з теми "MiRNA decoy"

1

Yoo, Jimeen, Roger J. Hajjar, and Dongtak Jeong. "Generation of Efficient miRNA Inhibitors Using Tough Decoy Constructs." In Methods in Molecular Biology, 41–53. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6588-5_3.

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2

Wong, Gigi, and Anthony A. Millar. "The Use of MicroRNA Decoy Technologies to Inhibit miRNA Function in Arabidopsis." In Methods in Molecular Biology, 227–38. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-9042-9_17.

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3

Li, Zhiming, and Chi-Meng Tzeng. "Integrated Analysis of miRNA and mRNA Expression Profiles to Identify miRNA Targets." In mRNA Decay, 141–48. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7540-2_10.

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4

Petri, Rebecca, and Johan Jakobsson. "Identifying miRNA Targets Using AGO-RIPseq." In mRNA Decay, 131–40. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-7540-2_9.

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5

Li, Guanglin, Zhiqiang Hao, Chunyan Fan, and Xianmiao Wu. "Genome-Wide Function Analysis of lincRNAs as miRNA Targets or Decoys in Plant." In Plant Epigenetics, 149–62. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-55520-1_8.

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6

Grosswendt, Stefanie, and Nikolaus Rajewsky. "Essentials of miRNA-dependent Control of mRNA Translation and decay, miRNA Targeting Principles, and Methods for Target Identification." In Essentials of Noncoding RNA in Neuroscience, 19–38. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-804402-5.00002-9.

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Тези доповідей конференцій з теми "MiRNA decoy"

1

Zangari, Joséphine, Marius Ilie, Florian Rouaud, Laurie Signetti, Mickaël Ohanna, Robin Didier, Barnabé Roméo, et al. "Abstract 3044: Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-3044.

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