Дисертації з теми "Mild traumatic brain injuries (mTBI)"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся з топ-36 дисертацій для дослідження на тему "Mild traumatic brain injuries (mTBI)".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.
Walters-Stewart, Coren Tiffany. "Non-linear Centre of Pressure Analysis During Quiet Stance: Application to Mild Traumatic Brain Injury." Thesis, Université d'Ottawa / University of Ottawa, 2017. http://hdl.handle.net/10393/36039.
Повний текст джерелаMounce, Luke Timothy Allan. "Outcome after mild traumatic brain injury : the interplay of concussion and post-traumatic stress symptoms." Thesis, University of Exeter, 2011. http://hdl.handle.net/10036/3303.
Повний текст джерелаNygren, de Boussard Catharina. "Studies on head trauma complications : with special reference to mild traumatic brain injury /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-836-X/.
Повний текст джерелаScandale, Joanne Bellini James L. "The tenuous self Narratives of individuals who have experienced mild traumatic brain injuries /." Related electronic resource: Current Research at SU : database of SU dissertations, recent titles available full text, 2004. http://wwwlib.umi.com/cr/syr/main.
Повний текст джерелаManderino, Lisa M. "Cognitive Functioning Under Hypoxic Stress in Individuals with History of Mild Traumatic Brain Injury." Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1591713552152285.
Повний текст джерелаMekwa, Julia Nobelungu. "Attention process training : its effectiveness in remediating attention and memory deficits following mild traumatic brain injury /." Thesis, Connect to this title online; UW restricted, 1996. http://hdl.handle.net/1773/7206.
Повний текст джерелаWong, Andrew. "Comparison of recovery time from uncomplicated sports-related mild traumatic brain injury (mTBI) in intercollegiate athletes: A baseline study." Thesis, The University of Arizona, 2013. http://hdl.handle.net/10150/281813.
Повний текст джерелаSports-related mild traumatic brain injuries (mTBIs) have become an increasingly popular topic. Cognitive and physical rest are the mainstays of management, but effective evidence-based therapies do not exist. Very few studies report mean recovery times from mTBI and even less for intercollegiate athletes. The primary aim is to retrospectively compare the recovery time in athletes from a large Division I University that suffered a sports-related mTBI during 2010 - 2012 to published data for quality assessment and improvement. Since the institution's concussion management follows current guidelines, no significant difference was expected. Secondary aims included comparing recovery times between gender, sport, and league. As reported in current literature, no significant gender differences were expected. 53 athletes with sports-related mTBI (27 male and 26 female) showed a mean recovery time of 10.11 days (95 % confidence interval [CI] = 8.58 - 11.65 days), statistically different than the time reported in 1 study of 7 days, but not in another of 7 - 10 days. Mean recovery time in males and females was 9.74 days (95 % CI = 7.38 - 12.1 days) and 10.5 days (95 % CI = 8.4 - 12.6 days), respectively. Mean recovery time in National Collegiate Athletic Association (NCAA) and non-NCAA (club) athletes was 9.91 days (95 % CI = 8.27 - 11.55) and 11.25 days (95 % CI = 5.87 - 16.63), respectively. A nonparametric Wilcoxon rank-sum test showed no significant variation between genders and between NCAA and non-NCAA athletes. Subgroup statistics of 13 sports were inconclusive due to inadequate power. However, the subgroup of male football athletes showed a mean recovery time of 6.5 days (95 % CI = 4.86 - 8.14 days), which was not significantly different than published rates. Multiple confounding variables were not well controlled for including: sport, gender, concussion severity, multiple concussions, etc. However, this study did highlight areas for quality improvement in the institution's concussion management plan. Further investigation with increased power and confounding variable control is indicated for a more definitive mean time to recovery. This study is the first to detail the mean time to recovery from sports-related mTBI in an intercollegiate athletic program. Similar studies should be done at other institutions for quality assessment and improvement of 4 concussion management. Such data will be useful in establishing a baseline for measure of efficacy in future investigations of therapeutic interventions.
Akin, Faith W., and Jorge M. Serrador. "Diagnosis and Treatment of Vestibular Disorders in mTBI." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/2430.
Повний текст джерелаClements, Andrea D. "Mild Traumatic Brain Injury in Multiple Trauma Patients: the Problem of Delayed Diagnosis." Digital Commons @ East Tennessee State University, 1997. https://dc.etsu.edu/etsu-works/7217.
Повний текст джерелаSpitz, Shelby E. "A Preliminary Examination of First-Line Healthcare Providers' Perceived Knowledge of and Referrals to Speech Language Pathologists Following a Mild Traumatic Brain Injury." Miami University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=miami1587120260821786.
Повний текст джерелаPals, Ingo [Verfasser], and Hermann J. [Akademischer Betreuer] Müller. "Deficits in visual attention after mild and severe traumatic brain injuries / Ingo Pals ; Betreuer: Hermann Müller." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://nbn-resolving.de/urn:nbn:de:bvb:19-211301.
Повний текст джерелаPals, Ingo [Verfasser], and Hermann [Akademischer Betreuer] Müller. "Deficits in visual attention after mild and severe traumatic brain injuries / Ingo Pals ; Betreuer: Hermann Müller." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2016. http://d-nb.info/1141053705/34.
Повний текст джерелаLopez, Carrie Lynn. "Primary Care Provider Knowledge of the Prevention, Screening, and Management of Mild Traumatic Brain Injuries in Adolescent Athletes." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/594948.
Повний текст джерелаLaubscher, Johannes Andries. "The neuropsychological and academic consequences of repeated mild and very mild traumatic brain injuries in rugby at a secondary school / J.A. Laubscher." Thesis, North-West University, 2006. http://hdl.handle.net/10394/1043.
Повний текст джерелаThesis (Ph.D. (Human Movement Science))--North-West University, Potchefstroom Campus, 2006.
Stålnacke, Britt-Marie. "Detection and outcome of mild traumatic brain injury in patients and sportsmen : persisting symptoms, disabilities and life satisfaction in relation to S-100B, NSE and cortisol /." Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-259.
Повний текст джерелаGattu, Ramtilak, Faith W. Akin, Anthony T. Cacace, Courtney D. Hall, Owen D. Murnane, E. Mark Haacke, and Joseph M. Furman. "Vestibular, Balance, Microvascular and White Matter Neuroimaging Characteristics of Blast Injuries and Mild Traumatic Brain Injury: Four Case Reports." Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/542.
Повний текст джерелаRogers, Jeffrey Michael. "Electrophysiological and neuropsychological assessment of automatic and controlled processing aspects of attention after mild traumatic brain injury." University of Western Australia. School of Psychology, 2007. http://theses.library.uwa.edu.au/adt-WU2007.0191.
Повний текст джерелаThomas, Shannon Lee. "THE EFFECTS OF INJURY MANAGEMENT PROTOCOL IN COLLEGE ATHLETES WITH SPORTS-RELATED HEAD INJURY: EVIDRNCE BASED RECOMMENDATIONS." Oxford, Ohio : Miami University, 2004. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1079993523.
Повний текст джерелаAlexander, Debbie. "The impact of repeated mild traumatic brain injuries (concussions) on the cognitive and academic functioning of early adolescent rugby union players: A controlled, longitudinal, prospective study." Thesis, University of the Western Cape, 2007. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_3611_1265940500.
Повний текст джерелаThis study investigated, within the context of Brain Reserve Capacity (BRC) theory, whether repeated concussions resulted in residual deficits in cognitive and academic functioning of early adolescent rugby players relative to non-contact sports controls.
Broughton, James William. "The effects of concussion dosage, gender, reported symptoms and expectations on long-term outcomes following sport-related concussion." Thesis, University of Exeter, 2016. http://hdl.handle.net/10871/24087.
Повний текст джерелаHealt, Nicholas. "Prevalence of pituitary dysfunction in psychiatric patients with mild head injuries." Thesis, 2020. https://hdl.handle.net/2144/42153.
Повний текст джерела(9804197), Matthew Hiskens. "Effects of novel pharmacological agents on markers of cellular and molecular health in a preclinical model of mild traumatic brain injury." Thesis, 2021. https://figshare.com/articles/thesis/Effects_of_novel_pharmacological_agents_on_markers_of_cellular_and_molecular_health_in_a_preclinical_model_of_mild_traumatic_brain_injury/20057240.
Повний текст джерелаBackground: Mild traumatic brain injuries (mTBI) are events with potentially debilitating short- and longterm consequences and may lead to neurodegenerative diseases such as chronic traumatic encephalopathy (CTE). An incomplete understanding of the mechanisms of disease progression has led to difficulty in identifying diagnostic and prognostic markers of mTBI and CTE, while treatment therapies remain elusive. Lines of evidence suggest that the antiinflammatory and neuroprotective agents celecoxib and minocycline may mitigate the injury processes initiated by mTBI, however a thorough investigation of these compounds in this context has not been undertaken. Accordingly, the aims of this research project were to: (i) investigate the behavioural, biochemical and molecular changes that are representative of repetitive mTBI and chronic neurodegeneration; and (ii) assess the implementation of minocycline and celecoxib in the inflammatory and excitotoxic pathways that are induced following mTBI. Methods: To meet these project aims, a series of reviews were conducted to ascertain the current knowledge gaps in mTBI research. A systematic review analysed the parameters and outcomes of mTBI animal modelling. A review was also undertaken to assess the current status of blood biomarker research for mTBI and CTE, and a third review described therapeutic targets for neuroprotection following mTBI and corresponding pharmacological treatments that have been investigated. These reviews provided rationale for our series of murine studies addressing the aforementioned aims. Study 1 examined differing modelling parameters to further understand the clinical, biochemical, and gene expression response to injury. Studies 2 and 3 used the findings of Study 1 to investigate the effectiveness of minocycline and celecoxib in mitigating mTBI-induced detriment to molecular and cognitive function. Results: The systematic review identified relevant mTBI modelling platforms and reported on subsequent changes to cognitive performance, neurodegenerative proteins, and neurodestructive genes. Study 1 used cumulative impacts to replicate the mTBI pathophysiology and clinical features described in the systematic review. Our pharmacology treatment studies found molecular measures of excitotoxicity and neurodegeneration induced by repetitive mTBI showed similar patterns of neuroprotection from minocycline and celecoxib in the hippocampus and cortex. However, glial cell involvement and inflammation was normalised by celecoxib in both the acute and chronic phases of recovery, but only in the chronic phase by minocycline. Interestingly, it was observed that behavioural detriment associated with mTBI following celecoxib administration did not reflect the neuroprotective gene expression changes. Conclusion: These investigations provide novel mechanistic data regarding microglial activation, inflammation, excitotoxicity, and neurodegeneration following repetitive mTBI. This work suggests that the pathways effected by minocycline and celecoxib are of importance in the alleviation of mTBI pathophysiology at chronic recovery. In turn, these investigations may help identify reliable mTBI-related diagnostic and prognostic markers and in developing potential treatments to mitigate the harmful effects of mTBI.
Trivino, Paredes Juan Sebastian. "Repeated mild traumatic brain injury is associated with acute microvascular damage in juvenile male and female rats." Thesis, 2021. http://hdl.handle.net/1828/13060.
Повний текст джерелаGraduate
Pinar, Cabeza de Vaca Cristina. "Effects of mild traumatic brain injury on hippocampal synaptic plasticity and behaviour in juvenile rats." Thesis, 2019. http://hdl.handle.net/1828/11359.
Повний текст джерелаGraduate
Sparrow, Barbara Jean. "Coping resources and the development of persistent postconcussional syndrome after a mild traumatic brain injury." Thesis, 2002. http://wwwlib.umi.com/cr/utexas/fullcit?p3106598.
Повний текст джерела(5929502), Sumra Bari. "ADVANCEMENTS IN NEUROIMAGING FOR MILD TRAUMATIC BRAIN INJURY AND MULTI-SITE RELIABILITY." Thesis, 2019.
Знайти повний текст джерелаHead injuries in collision sports have been linked to long-term neurological disorders. High school collision sport athletes, a population vulnerable to head injuries, are at a greater risk of chronic damage. Various studies have indicated significant deviations in brain function due to the accumulation of repetitive low-level subconcussive impacts to the head without externally observable cognitive symptoms. The aim of this study was to investigate metabolic changes in asymptomatic collision sport athletes across time within their competition season and as a function of mechanical force to their head. For this purpose, Proton Magnetic Resonance Spectroscopy (MRS) was used as a tool to detect altered brain metabolism in high school collision sport athletes (football and soccer) without diagnosed concussion. Also, sensors were attached to each athletes head to collect the count and magnitude of head impacts during their games and practices. Transient neurometabolic alterations along with prolonged recovery were observed in collision sport athletes.
Multi-site studies are becoming important to increase statistical power, enhance generalizability, and to improve the likelihood of pooling relevant subgroups together activities which are otherwise limited by the availability of patients or funds at a single site. Even with harmonized imaging sequences, site-dependent variability can mask the advantages of these multi-site studies. The aim of this study was to assess multi-site reproducibility in resting-state functional connectivity fingerprints, and to improve identifiability of obtained functional connectomes. We evaluated individual fingerprints in test- retest visit pairs within and across two sites and present a generalized framework based on principal component analysis (PCA) to improve identifiability. The optimally reconstructed functional connectomes using PCA showed a substantial improvement in individual fingerprinting of the subjects within and across the two sites and test-retest visit pairs relative to the original data. Results demonstrate that the data-driven method presented in the study can improve identifiability in resting-state functional connectomes in multi-site studies.
Sloan, Ann. "Behavioural and affective functioning in children after mild traumatic brain injury." Thesis, 2010. https://vuir.vu.edu.au/30232/.
Повний текст джерелаKarr, Justin Elliott. "A Systematic Review of Meta-Analyses on the Cognitive Sequelae of mild Traumatic Brain Injury and an Empirical Study on Executive Functions and Intra-Individual Variability following Concussion." Thesis, 2013. http://hdl.handle.net/1828/4716.
Повний текст джерелаGraduate
0622
jkarr@uvic.ca
Irwin, Julie K. "When the past becomes the “good old days”: adolescents underestimate pre-injury post-concussion-like symptoms by one month after mild traumatic brain injury." Thesis, 2018. https://dspace.library.uvic.ca//handle/1828/9782.
Повний текст джерелаGraduate
2019-07-10
Harris, Andrew. "Head injuries from sports and recreation presenting to emergency departments in Edmonton, Alberta." Master's thesis, 2010. http://hdl.handle.net/10048/1458.
Повний текст джерелаEpidemiology
Edrington, Sarah Katherine. "School-based speech-language pathologists and concussion : training, knowledge, and experience." 2013. http://hdl.handle.net/2152/22397.
Повний текст джерелаtext
Daggett, Virginia Sue. "Needs and Concerns of Combat Veterans with Mild Traumatic Brain Injury and the Development of the Veterans Compensate, Adapt and Reintegrate Intervention." Thesis, 2010. http://hdl.handle.net/1805/2252.
Повний текст джерелаTraumatic brain injury (TBI) has emerged as a major cause of morbidity among U.S. soldiers who have served in Iraq and Afghanistan. Even mild TBI (mTBI) can result in cognitive impairments that can impact how veterans experience such things as physical symptoms, emotions and behaviors, instrumental activities of daily living, interpersonal interactions, and community reintegration. The purpose of this study was to develop a comprehensive self-management intervention for veterans with mTBI to facilitate their community reintegration upon returning from deployment to combat zones. This study was conducted in two Phases. Phase I entailed collecting qualitative data regarding needs, concerns, strategies used, and advice given by eight veterans with mTBI, guided by a conceptual model derived from Ferrans’ and colleagues’ health-related quality of life model and the TBI literature. Six key categories and predominant themes emerged providing further support for the model (cognitive impairments, physical symptoms, emotions and behaviors, instrumental activities of daily living, interpersonal interactions, and community reintegration). Guided by the conceptual model, a mTBI Veteran Needs and Concerns Checklist and 14 algorithms making up the VETeranS Compensate, Adapt, REintegrate (VETSCARE) intervention were developed. Phase II entailed obtaining review of the mTBI Veteran Needs and Concerns Checklist and the 14 VETSCARE algorithms from six TBI experts. On a scale of 1 to 5, with 5 being strongly agree, expert ratings provided moderate evidence of content validity for the checklist (3.33), and for the 14 algorithms (problem relevance 3.92, accuracy 3.73, feasibility 3.80, acceptability 3.84). The average overall expert rating for the VETSCARE intervention was 3.82. The checklist and the 14 algorithms are being revised based on specific comments provided by the experts. Once revised, the mTBI Veteran Needs and Concerns Checklist and the VETSCARE intervention will be tested for feasibility in a future pilot study with veterans with mTBI who have recently returned from combat zones in Iraq and Afghanistan.
Halliday, Drew. "Executive motor control across the lifespan: clinical insights from Attention Deficit Hyperactivity Disorder, concussion and mild cognitive impairment." Thesis, 2020. http://hdl.handle.net/1828/11830.
Повний текст джерелаGraduate
Haladuick, Tyler. "Numerical Simulation of Blast Interaction with the Human Body: Primary Blast Brain Injury Prediction." Thesis, 2014. http://hdl.handle.net/10012/8265.
Повний текст джерелаBolduc-Teasdale, Julie. "Marqueurs électrophysiologiques des dysfonctions attentionnelles et de leur récupération suite à un traumatisme craniocérébral léger." Thèse, 2015. http://hdl.handle.net/1866/16039.
Повний текст джерелаThe main objective of this thesis was to obtain, using cognitive electrophysiology, biomarkers of mild traumatic brain injury (TBI) for different levels of information processing such as selective attention, visuo-attentional decision making and processes associated with the execution of a deliberate response. The fundamental assumption was that the lesion-producing mechanisms as well as the pathophysiology associated with mTBI leads to visuo-attentional dysfunctions, at least during the sub-acute period following the mTBI (i.e. between 1 and 3 months post-trauma), as measured by a novel electrophysiological paradigm developed for this purpose. This thesis presents two articles describing the work accomplished to meet these objectives, and verify the underlying assumptions. The first article presents the approach used to create a novel visuo-spatial attention task enabling the identification of electrophysiological (amplitude, latency) and behavioural (reaction time) indexes related to early visual and attentional processing (P1, N1, N2-nogo, P2, Ptc), selective visual attention (N2pc, SPCN) and decision-making processes (P3b, P3a) in a group of normal participants (i.e. without neurological injury). The second article presents a study of the persisting effects of a mTBI on visuo-attentional functions through the identification of targeted electrophysiological markers (amplitude, latency), and from behavioural data (task-related reaction time and neuropsychological tests results) in two cohorts of symptomatic mTBI individuals, one during the sub-acute phase (3 first months post-injury), the other during the chronic phase (6 months to 1 year post-injury), in comparison to a group of normal control participants. The results presented in this thesis indicate that it was has been possible to create a simple, rapid and low-cost task enabling the study of the various levels of information processing involved in the deployment of visuospatial attention. Subsequently, the use of this task in patients with mTBI tested during the sub-acute phase or the chronic phase allowed to identify differential impairment and recovery profiles for each of the components studied. Indeed, while the early components associated with early visual information processing (P1, N1, N2) were intact, certain attentional (P2) and cognitive-attentionnal (the P3a, P3b) components were affected, suggesting dysfunction in the spatio-temporal dynamics of attention, orientation of attention, and working memory, in the short- and/or long-term following mTBI, this is the presence of neuropsychological deficits mostly in the sub-acute phase and of persisting post-mTBI symptomatology. This thesis emphasizes the importance of developing sensitive and comprehensive diagnostic tools allowing to objectively identify the various cognitive processes and sub-processes that are likely to be affected after a mTBI.
Piponnier, Jean-Claude. "Impacts fonctionnels du traumatisme craniocérébral léger sur la vision et l'équilibre postural chez l'adulte." Thèse, 2015. http://hdl.handle.net/1866/13911.
Повний текст джерелаMild traumatic brain injury (mTBI) has complex effects on several brain functions that can be difficult to assess and follow-up. Visual and balance problems are frequently reported after an mTBI. Furthermore, these problems can still affect mTBI individuals far beyond the acute stage of injury. However, standard clinical assessments of vision and balance most often fail to objectivize these symptoms, especially if they are lingering. Moreover, to our knowledge, no longitudinal study investigated either mTBI-related deficits of visual perception per se, or mTBI-related balance deficits in adults. The aim of this project was to determine the nature and duration of the effects of such a traumatism on visual perception as well as on postural stability, by evaluating mTBI and control adults over a one-year period. Exactly the same subjects participated in both experiments, which took place on the same days for every subject. The impact of mTBI on the visual perception of sine-wave gratings defined by first-and second-order characteristics was, first, investigated. Fifteen adults diagnosed with mTBI were assessed at 15 days, 3 months and 12 months after injury. Fifteen matched controls followed the same testing schedule. Reaction times (RTs) for flicker detection and motion direction discrimination were measured. Stimulus contrast of first- and second-order patterns was equated to control for visibility, and correct-response RT means, standard deviations (SDs), medians, and interquartile ranges (IQRs) were calculated. The level of symptoms was also evaluated to compare it to RT data. In general in mTBI, RTs were longer and more variable (ie., larger SDs and IQRs), than those of controls. In addition, mTBI participants’ RTs to first-order stimuli were shorter than those to second-order stimuli, and more irregular for first- than for second-order stimuli in the motion condition. All these observations were made over the 3 sessions. The level of symptoms observed in mTBI was higher than that of control participants and this difference did also persist up to one year after the brain injury, despite an improvement. The second experiment, then, investigated the impact of mTBI on postural control. To achieve that, antero-posterior body sway amplitude (BSA) and postural instability (given by body sway velocity root mean square, vRMS) during upright stance, feet together, on a firm surface, were measured in five different conditions: with eyes closed and in a 3D virtual reality tunnel, either static or sinusoidally moving in the antero-posterior direction at 3 different velocities. Balance measures derived from clinical tests, Bruininks-Oseretsky Test of Motor Proficiency 2nd edition (BOT-2) and Balance Error Scoring System (BESS), were also used. Participants diagnosed with mTBI exhibited more postural instability (i.e. higher body sway vRMS) than control participants at 2 weeks and at 3 months post-injury, regardless of the testing condition. These mTBI-related balance deficits were no longer present one year postinjury. These results also suggest that visual processing impairments revealed in the first experiment might have contributed to mTBI-related balance deficits. Anteroposterior BSA as well as measures derived from clinical tests for balance assessment did not appear to be sensitive enough to quantify postural deficits of mTBI participants. The combination of RT measures with particular stimulus properties appeared to be a highly sensitive method for measuring mTBI-induced visuomotor anomalies, and to provide a fine probe of the underlying mechanisms when the brain is exposed to mild trauma. Likewise, postural instability measures prove to be sensitive enough for measuring mTBI-induced balance deficits. Developing screening tests in this respect intended for early post-mTBI use would be of interest. Also, studying relationships of such deficits with performance in daily life activities, such as school, work, or sports, is crucial in order to determine the functional impacts of these alterations in visuomotor and balance functions.