Статті в журналах з теми "Microhomology mediated recombination"
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Jiang, Yuning. "Contribution of Microhomology to Genome Instability: Connection between DNA Repair and Replication Stress." International Journal of Molecular Sciences 23, no. 21 (October 26, 2022): 12937. http://dx.doi.org/10.3390/ijms232112937.
Повний текст джерелаXu, Yijiang, Hang Zhou, Ginell Post, Hong Zan, and Paolo Casali. "Rad52 mediates class-switch DNA recombination to IgD." Journal of Immunology 208, no. 1_Supplement (May 1, 2022): 112.17. http://dx.doi.org/10.4049/jimmunol.208.supp.112.17.
Повний текст джерелаLee-Theilen, Mieun, Allysia J. Matthews, Dierdre Kelly, Simin Zheng, and Jayanta Chaudhuri. "CtIP promotes microhomology-mediated alternative end joining during class-switch recombination." Nature Structural & Molecular Biology 18, no. 1 (December 5, 2010): 75–79. http://dx.doi.org/10.1038/nsmb.1942.
Повний текст джерелаFrancis, Nigel J., Bairbre McNicholas, Atif Awan, Mary Waldron, Donal Reddan, Denise Sadlier, David Kavanagh, et al. "A novel hybrid CFH/CFHR3 gene generated by a microhomology-mediated deletion in familial atypical hemolytic uremic syndrome." Blood 119, no. 2 (January 12, 2012): 591–601. http://dx.doi.org/10.1182/blood-2011-03-339903.
Повний текст джерелаAhrabi, Sara, Sovan Sarkar, Sophia X. Pfister, Giacomo Pirovano, Geoff S. Higgins, Andrew C. G. Porter, and Timothy C. Humphrey. "A role for human homologous recombination factors in suppressing microhomology-mediated end joining." Nucleic Acids Research 44, no. 12 (April 29, 2016): 5743–57. http://dx.doi.org/10.1093/nar/gkw326.
Повний текст джерелаChan, C. Y., M. Kiechle, P. Manivasakam, and R. H. Schiestl. "Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae." Nucleic Acids Research 35, no. 15 (July 11, 2007): 5051–59. http://dx.doi.org/10.1093/nar/gkm442.
Повний текст джерелаLing, Alexanda K., Clare C. So, Michael X. Le, Audrey Y. Chen, Lisa Hung, and Alberto Martin. "Double-stranded DNA break polarity skews repair pathway choice during intrachromosomal and interchromosomal recombination." Proceedings of the National Academy of Sciences 115, no. 11 (February 22, 2018): 2800–2805. http://dx.doi.org/10.1073/pnas.1720962115.
Повний текст джерелаChan, Cecilia Y., and Robert H. Schiestl. "Rad1, rad10 and rad52 Mutations Reduce the Increase of Microhomology Length during Radiation-Induced Microhomology-Mediated Illegitimate Recombination in Saccharomyces cerevisiae." Radiation Research 172, no. 2 (August 1, 2009): 141. http://dx.doi.org/10.1667/rr1675.1.
Повний текст джерелаNagai, Koki, Hirohito Shima, Miki Kamimura, Junko Kanno, Erina Suzuki, Akira Ishiguro, Satoshi Narumi, Shigeo Kure, Ikuma Fujiwara, and Maki Fukami. "Xp22.31 Microdeletion due to Microhomology-Mediated Break-Induced Replication in a Boy with Contiguous Gene Deletion Syndrome." Cytogenetic and Genome Research 151, no. 1 (2017): 1–4. http://dx.doi.org/10.1159/000458469.
Повний текст джерелаMeyer, Damon, Becky Xu Hua Fu та Wolf-Dietrich Heyer. "DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae". Proceedings of the National Academy of Sciences 112, № 50 (25 листопада 2015): E6907—E6916. http://dx.doi.org/10.1073/pnas.1507833112.
Повний текст джерелаXu, Ran, Ziyi Pan, and Takuro Nakagawa. "Gross Chromosomal Rearrangement at Centromeres." Biomolecules 14, no. 1 (December 24, 2023): 28. http://dx.doi.org/10.3390/biom14010028.
Повний текст джерелаRobert, Isabelle, Françoise Dantzer, and Bernardo Reina-San-Martin. "Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination." Journal of Experimental Medicine 206, no. 5 (April 13, 2009): 1047–56. http://dx.doi.org/10.1084/jem.20082468.
Повний текст джерелаWang, Xiaobin S., Junfei Zhao, Foon Wu-Baer, Zhengping Shao, Brian J. Lee, Olivia M. Cupo, Raul Rabadan, Jean Gautier, Richard Baer, and Shan Zha. "CtIP-mediated DNA resection is dispensable for IgH class switch recombination by alternative end-joining." Proceedings of the National Academy of Sciences 117, no. 41 (September 28, 2020): 25700–25711. http://dx.doi.org/10.1073/pnas.2010972117.
Повний текст джерелаChen, Changming, Xiaoling Xie, Xi Wu, Yeling Lu, Xuefeng Wang, Wenman Wu, Yiqun Hu, and Qiulan Ding. "Complex recombination with deletion in the F8 and duplication in the TMLHE mediated by int22h copies during early embryogenesis." Thrombosis and Haemostasis 117, no. 08 (2017): 1478–85. http://dx.doi.org/10.1160/th17-01-0046.
Повний текст джерелаSaribasak, Huseyin, Robert W. Maul, Zheng Cao, Rhonda L. McClure, William Yang, Daniel R. McNeill, David M. Wilson, and Patricia J. Gearhart. "XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes." Journal of Experimental Medicine 208, no. 11 (October 3, 2011): 2209–16. http://dx.doi.org/10.1084/jem.20111135.
Повний текст джерелаEhrenstein, M. R., C. Rada, A. M. Jones, C. Milstein, and M. S. Neuberger. "Switch junction sequences in PMS2-deficient mice reveal a microhomology-mediated mechanism of Ig class switch recombination." Proceedings of the National Academy of Sciences 98, no. 25 (November 20, 2001): 14553–58. http://dx.doi.org/10.1073/pnas.241525998.
Повний текст джерелаChen, Xiaojiang S., та Richard T. Pomerantz. "DNA Polymerase θ: A Cancer Drug Target with Reverse Transcriptase Activity". Genes 12, № 8 (27 липня 2021): 1146. http://dx.doi.org/10.3390/genes12081146.
Повний текст джерелаBothmer, Anne, Davide F. Robbiani, Niklas Feldhahn, Anna Gazumyan, Andre Nussenzweig, and Michel C. Nussenzweig. "53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination." Journal of Experimental Medicine 207, no. 4 (April 5, 2010): 855–65. http://dx.doi.org/10.1084/jem.20100244.
Повний текст джерелаDecottignies, Anabelle. "Microhomology-Mediated End Joining in Fission Yeast Is Repressed by Pku70 and Relies on Genes Involved in Homologous Recombination." Genetics 176, no. 3 (May 4, 2007): 1403–15. http://dx.doi.org/10.1534/genetics.107.071621.
Повний текст джерелаDing, Qiulan, Guoling You, Jing Dai, Xiaodong Xi, Hongli Wang, Xi Wu, Yeling Lu, and Xuefeng Wang. "Characterisation of large F9 deletions in seven unrelated patients with severe haemophilia B." Thrombosis and Haemostasis 112, no. 09 (2014): 459–65. http://dx.doi.org/10.1160/th13-12-1060.
Повний текст джерелаYou, Guoling, Kun Chi, Yeling Lu, Qiulan Ding, Jing Dai, Xiaodong Xi, Hongli Wang, and Xuefeng Wang. "Identification and characterisation of a novel aberrant pattern of intron 1 inversion with concomitant large insertion and deletion within the F8 gene." Thrombosis and Haemostasis 112, no. 08 (2014): 264–70. http://dx.doi.org/10.1160/th13-10-0892.
Повний текст джерелаKohli, Ajay, Simon Griffiths, Natalia Palacios, Richard M Twyman, Philippe Vain, David A. Laurie, and Paul Christou. "Molecular characterization of transforming plasmid rearrangements in transgenic rice reveals a recombination hotspot in the CaMV 35S promoter and confirms the predominance of microhomology mediated recombination." Plant Journal 17, no. 6 (March 1999): 591–601. http://dx.doi.org/10.1046/j.1365-313x.1999.00399.x.
Повний текст джерелаFiori, Mariangela Stefania, Luca Ferretti, Antonello Di Nardo, Lele Zhao, Susanna Zinellu, Pier Paolo Angioi, Matteo Floris, et al. "A Naturally Occurring Microhomology-Mediated Deletion of Three Genes in African Swine Fever Virus Isolated from Two Sardinian Wild Boars." Viruses 14, no. 11 (November 14, 2022): 2524. http://dx.doi.org/10.3390/v14112524.
Повний текст джерелаFeng, Wanjuan, Dennis A. Simpson, Jang-Eun Cho, Juan Carvajal-Garcia, Chelsea M. Smith, Kathryn M. Headley, Nate Hathaway, Dale A. Ramsden, and Gaorav P. Gupta. "Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks." Nucleic Acids Research 49, no. 9 (May 8, 2021): 5095–105. http://dx.doi.org/10.1093/nar/gkab299.
Повний текст джерелаStachler, Aris-Edda, Julia Wörtz, Omer S. Alkhnbashi, Israela Turgeman-Grott, Rachel Smith, Thorsten Allers, Rolf Backofen, Uri Gophna, and Anita Marchfelder. "Adaptation induced by self-targeting in a type I-B CRISPR-Cas system." Journal of Biological Chemistry 295, no. 39 (July 28, 2020): 13502–15. http://dx.doi.org/10.1074/jbc.ra120.014030.
Повний текст джерелаDahal, Sumedha, and Sathees C. Raghavan. "Mitochondrial genome stability in human: understanding the role of DNA repair pathways." Biochemical Journal 478, no. 6 (March 19, 2021): 1179–97. http://dx.doi.org/10.1042/bcj20200920.
Повний текст джерелаWang, Wenjie, Kuan Li, Zhuo Yang, Quancan Hou, Wei W. Zhao, and Qianwen Sun. "RNase H1C collaborates with ssDNA binding proteins WHY1/3 and recombinase RecA1 to fulfill the DNA damage repair in Arabidopsis chloroplasts." Nucleic Acids Research 49, no. 12 (June 16, 2021): 6771–87. http://dx.doi.org/10.1093/nar/gkab479.
Повний текст джерелаÖz, Robin, Sean M. Howard, Rajhans Sharma, Hanna Törnkvist, Ilaria Ceppi, Sriram KK, Erik Kristiansson, Petr Cejka, and Fredrik Westerlund. "Phosphorylated CtIP bridges DNA to promote annealing of broken ends." Proceedings of the National Academy of Sciences 117, no. 35 (August 19, 2020): 21403–12. http://dx.doi.org/10.1073/pnas.2008645117.
Повний текст джерелаZhao, Yuqin, Kaiping Hou, Yu Liu, Yinan Na, Chao Li, Haoyuan Luo, and Hailong Wang. "Helicase HELQ: Molecular Characters Fit for DSB Repair Function." International Journal of Molecular Sciences 25, no. 16 (August 8, 2024): 8634. http://dx.doi.org/10.3390/ijms25168634.
Повний текст джерелаDohrn, Lisa, Daniela Salles, Simone Y. Siehler, Julia Kaufmann, and Lisa Wiesmüller. "BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1." Biochemical Journal 441, no. 3 (January 16, 2012): 919–28. http://dx.doi.org/10.1042/bj20110314.
Повний текст джерелаTruong, L. N., Y. Li, L. Z. Shi, P. Y. H. Hwang, J. He, H. Wang, N. Razavian, M. W. Berns, and X. Wu. "Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells." Proceedings of the National Academy of Sciences 110, no. 19 (April 22, 2013): 7720–25. http://dx.doi.org/10.1073/pnas.1213431110.
Повний текст джерелаElert-Dobkowska, Ewelina, Iwona Stepniak, Wiktoria Radziwonik-Fraczyk, Amir Jahic, Christian Beetz, and Anna Sulek. "SPAST Intragenic CNVs Lead to Hereditary Spastic Paraplegia via a Haploinsufficiency Mechanism." International Journal of Molecular Sciences 25, no. 9 (May 3, 2024): 5008. http://dx.doi.org/10.3390/ijms25095008.
Повний текст джерелаTomasini, Paula Pellenz, Temenouga Nikolova Guecheva, Natalia Motta Leguisamo, Sarah Péricart, Anne-Cécile Brunac, Jean Sébastien Hoffmann, and Jenifer Saffi. "Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer." Cancers 13, no. 13 (June 23, 2021): 3130. http://dx.doi.org/10.3390/cancers13133130.
Повний текст джерелаLi, Zhichao, and Ralph Bock. "Rapid functional activation of a horizontally transferred eukaryotic gene in a bacterial genome in the absence of selection." Nucleic Acids Research 47, no. 12 (May 20, 2019): 6351–59. http://dx.doi.org/10.1093/nar/gkz370.
Повний текст джерелаLukashchuk, Natalia, Joshua Armenia, Luis Tobalina, Thomas Hedley Carr, Tsveta Milenkova, Ying L. Liu, Richard T. Penson, Mark E. Robson, and Elizabeth Harrington. "BRCA reversion mutations mediated by microhomology-mediated end joining (MMEJ) as a mechanism of resistance to PARP inhibitors in ovarian and breast cancer." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): 5559. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.5559.
Повний текст джерелаLukashchuk, Natalia, Joshua Armenia, Luis Tobalina, Thomas Hedley Carr, Tsveta Milenkova, Ying L. Liu, Richard T. Penson, Mark E. Robson, and Elizabeth Harrington. "BRCA reversion mutations mediated by microhomology-mediated end joining (MMEJ) as a mechanism of resistance to PARP inhibitors in ovarian and breast cancer." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): 5559. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.5559.
Повний текст джерелаHays, Michelle, Katja Schwartz, Danica T. Schmidtke, Dimitra Aggeli, and Gavin Sherlock. "Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by retrotransposons and microhomology-mediated recombination." PLOS Genetics 19, no. 5 (May 16, 2023): e1010747. http://dx.doi.org/10.1371/journal.pgen.1010747.
Повний текст джерелаProvasek, Vincent E., Joy Mitra, Vikas H. Malojirao, and Muralidhar L. Hegde. "DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders." International Journal of Molecular Sciences 23, no. 9 (April 22, 2022): 4653. http://dx.doi.org/10.3390/ijms23094653.
Повний текст джерелаZhao, Zhihua, Hanshuo Zhang, Tuanlin Xiong, Junyi Wang, Di Yang, Dan Zhu, Juan Li, et al. "Suppression of SHROOM1 Improves In Vitro and In Vivo Gene Integration by Promoting Homology-Directed Repair." International Journal of Molecular Sciences 21, no. 16 (August 13, 2020): 5821. http://dx.doi.org/10.3390/ijms21165821.
Повний текст джерелаLiu, Yu-Chang, Chih-Hao Huang, and Ching-Chun Chang. "A Transcriptomic Analysis of Tobacco Leaf with the Functional Loss of the Plastid rpoB Operon Caused by TALEN-Mediated Double-Strand Breakage." Plants 11, no. 21 (October 26, 2022): 2860. http://dx.doi.org/10.3390/plants11212860.
Повний текст джерелаAnand, Roopesh, Erika Buechelmaier, Ondrej Belan, Matthew Newton, Aleksandra Vancevska, Artur Kaczmarczyk, Tohru Takaki, David S. Rueda, Simon N. Powell, and Simon J. Boulton. "HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51." Nature 601, no. 7892 (December 22, 2021): 268–73. http://dx.doi.org/10.1038/s41586-021-04261-0.
Повний текст джерелаAlexander, Jessica L., Kelly Beagan, Terry L. Orr-Weaver, and Mitch McVey. "Multiple mechanisms contribute to double-strand break repair at rereplication forks inDrosophilafollicle cells." Proceedings of the National Academy of Sciences 113, no. 48 (November 14, 2016): 13809–14. http://dx.doi.org/10.1073/pnas.1617110113.
Повний текст джерелаTsuji, Hideo, Hiroko Ishii-Ohba, Takanori Katsube, Hideki Ukai, Shiro Aizawa, Masahiro Doi, Kyoji Hioki, and Toshiaki Ogiu. "Involvement of Illegitimate V(D)J Recombination or Microhomology-Mediated Nonhomologous End-Joining in the Formation of Intragenic Deletions of the Notch1 Gene in Mouse Thymic Lymphomas." Cancer Research 64, no. 24 (December 15, 2004): 8882–90. http://dx.doi.org/10.1158/0008-5472.can-03-1163.
Повний текст джерелаHaberland, Vivien M. M., Simon Magin, George Iliakis, and Andrea Hartwig. "Impact of Manganese and Chromate on Specific DNA Double-Strand Break Repair Pathways." International Journal of Molecular Sciences 24, no. 12 (June 20, 2023): 10392. http://dx.doi.org/10.3390/ijms241210392.
Повний текст джерелаJiang, Yuning, and Tarek Abbas. "Abstract 6107: Novel roles for AMBRA1 in regulating DNA double-strand breaks." Cancer Research 83, no. 7_Supplement (April 4, 2023): 6107. http://dx.doi.org/10.1158/1538-7445.am2023-6107.
Повний текст джерелаYan, Dan, Yao Zhang, Yan Zhang, Jingxi Zhang, Bin Wang, Huixian Chen, Jingxue Shi, Xiaoling Lin, Jincong Zhuo та Kevin Zhou. "Abstract 4532: Discovery of DAT-1000A, a potent Polθ inhibitor that significantly enhances anti-tumor efficacy in combination with PARP inhibitor in homologous-recombination-deficient tumors". Cancer Research 84, № 6_Supplement (22 березня 2024): 4532. http://dx.doi.org/10.1158/1538-7445.am2024-4532.
Повний текст джерелаPatterson-Fortin, Jeffrey, Heta Jadhav, Constantia Pantelidou, Tin Phan, Carter Grochala, Anita K. Mehta, Jennifer L. Guerriero, et al. "Abstract 6190: Polymerase theta inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in BRCA-deficient cancers." Cancer Research 83, no. 7_Supplement (April 4, 2023): 6190. http://dx.doi.org/10.1158/1538-7445.am2023-6190.
Повний текст джерелаLe, Bac Viet, Umeshkumar Vekariya, Monika Toma, Margaret Nieborowska-Skorska, Marie-Christine Caron, George Vassiliou, Malgorzata Gozdecka та ін. "Inactivation of DNA Polymerase Theta (PolΘ) Is Synthetic Lethal in DNMT3A Mutated Myeloid Malignancies - Potential Clinical Applications". Blood 142, Supplement 1 (28 листопада 2023): 580. http://dx.doi.org/10.1182/blood-2023-174333.
Повний текст джерелаSamnotra, Vivek, Veronica Moroz, Luda Shtessel, Mita Kuchimanchi, Patrick Hanafin, Malar Pannirselvam, Aishwarya Bhaskar, et al. "First-in-human, phase 1/2 study of GSK4524101, an oral DNApolymerase theta inhibitor (POLQi), alone or combined with the poly(ADP-ribose) polymerase (PARP) inhibitor (PARPi) niraparib in adults with solid tumors." Journal of Clinical Oncology 42, no. 16_suppl (June 1, 2024): TPS3174. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.tps3174.
Повний текст джерелаToma, Monika, Margaret Nieborowska-Skorska, Adam Karami, Monika Pepek, Tomasz Stoklosa, and Tomasz Skorski. "Clonal Targeting of DNA Damage Response Pathways Eradicates Myeloproliferative Neoplasms." Blood 142, Supplement 1 (November 28, 2023): 120. http://dx.doi.org/10.1182/blood-2023-174280.
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