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McKay, Athena S., Adam Paberzs, Patricia Piechowski, Donald Vereen, and Susan Woolford. "4449 Building Capacity in the Flint Community in the Midst of the Ongoing Water Crisis." Journal of Clinical and Translational Science 4, s1 (June 2020): 82. http://dx.doi.org/10.1017/cts.2020.262.
Повний текст джерелаАнотація:
OBJECTIVES/GOALS: Examining the impact of the Building Capacity for Research and Action (BCRA) Award created by the Community Engagement (CE) Program at the Michigan Institute for Clinical & Health Research (MICHR)--a Clinical & Translational Science Award (CTSA) site at the University of Michigan--in partnership with Community Based Organization Partners (CBOP). METHODS/STUDY POPULATION: The BCRA is a funding mechanism that supports new community-engaged research (CEnR) partnerships and projects that address community-identified health needs in Flint, Michigan. BCRA projects are required to be Flint-based and inclusive of both community and academic partners. A study section consisting of 10 MICHR-affiliated faculty and community partners reviewed proposals and made funding decisions. Funded teams were trained on Institutional Review Board (IRB) and reporting requirements by CE staff. MICHR provides support to BCRA-funded teams through monthly email correspondence with the CE Flint connector, budget review, mediation, regulatory assurance of IRB and the National Center for Advancing Translational Science (NCATS) requirements, coordinating six-month and final reporting, and hosting an annual stakeholder meet and greet. RESULTS/ANTICIPATED RESULTS: In 2017, the BCRA Award submitted its first request for proposals. It received 20 applications in 2018, and selected eight awardees, providing them with a total of $60,000 in funding. Four received $5,000 for partnership development and another four received $10,000 for their research projects. The BCRA Award received 16 applications in 2019, expanding its academic pool to include the University of Chicago, U-M Flint, Michigan State University, and Michigan State University-Flint in addition to the University of Michigan. Five recipients were selected and received a total of $45,000 in funding. One was awarded $5,000 for partnership development and another four were awarded $10,000 for their research projects. MICHR has invested over $100,000 in Flint through this mechanism, which was renewed in 2019. DISCUSSION/SIGNIFICANCE OF IMPACT: Each awardee presented at the annual stakeholder meet and greet. They showcased their projects with a brief overview and spoke about their expectations, lessons learned, partnership strengths and challenges, translational issues, and proposed next steps for subsequent grants, publications.
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Ajrouch, Kristine J., Irving E. Vega, Toni C. Antonucci, Wassim Tarraf, Noah J. Webster, and Laura B. Zahodne. "Partnering with Middle Eastern/Arab American and Latino Immigrant Communities to Increase Participation in Alzheimer’s Disease Research." Ethnicity & Disease 30, Suppl (November 19, 2020): 765–74. http://dx.doi.org/10.18865/ed.30.s2.765.
Повний текст джерелаАнотація:
Purpose: Recruitment and retention of US ethnic groups traditionally underrepresented in research continues to pose challenges. The Michigan Center for Contextual Factors in Alzheimer’s Disease (MCCFAD) engages with two underserved immigrant communities in Michigan – Middle Eastern/Arab Americans in metro-Detroit and Latinos in the Grand Rapids area – to recruit and retain two Participant Resource Pools (PRP).Procedures: We adapt an existing community-based participatory research (CBPR) approach to recruit Middle Eastern/Arab American and Latino adults of all ages for Alzheimer’s disease and related dementia (ADRD) research. Using American Community Survey (2014-2018) data, we compare socio-demographic characteristics of Middle Eastern/Arab Americans and Latinos living in Michigan to our PRPs. Assessment tools and community advisory board feedback identified missteps and culturally sensitive solutions.Main Findings: In the first year of MCCFAD activities, 100 Middle Eastern/ Arab Americans and 117 Latinos joined the MCCFAD PRPs. Comparisons to state-level data showed that PRP participants were on average older and more likely to be female than the Middle Eastern/Arab American and Latino populations in Michigan. Further, Middle Eastern/Arab Americans in the PRP reported higher education levels while Latinos reported lower education levels than their respective statewide populations. Community partnerships/feedback identified the importance of connecting with community leaders, attending to matters of within-group diversity, as well as language and semantics.Conclusion: Partnership with communities to develop culturally targeted and sensitive community health events can fill a significant gap in addressing ADRD health disparities by establishing sustainable relationships to increase participation in ADRD research. Ethn Dis. 2020;30(Suppl 2):765-774; doi:10.18865/ed.30.S2.765
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Johnson, Jennifer E., Ann B. Price, Alla Sikorskii, Kent D. Key, Brandon Taylor, Susan Lamphere, Christine Huff, Morgan Cinader, and Caron Zlotnick. "Protocol for the Healing After Loss (HeAL) Study: a randomised controlled trial of interpersonal psychotherapy (IPT) for major depression following perinatal loss." BMJ Open 12, no. 4 (April 2022): e057747. http://dx.doi.org/10.1136/bmjopen-2021-057747.
Повний текст джерелаАнотація:
IntroductionThis protocol describes a study testing the efficacy of interpersonal psychotherapy (IPT) for major depressive disorder following perinatal loss (early and late fetal death and early neonatal death). Perinatal loss is associated with elevated risk of major depressive disorder and post-traumatic stress disorder (PTSD). Perinatal loss conveys specific treatment needs. The trial will be the first fully powered randomised trial of treatment for any psychiatric disorder following perinatal loss.Methods and analysisA sample of 274 women in Flint and Detroit areas in Michigan who experience a major depressive episode following a perinatal loss will be randomised to group IPT for perinatal loss or to group coping with depression. We anticipate that 50% of the sample will have co-occurring PTSD. Assessments occur at baseline, mid-treatment (8 weeks), post-treatment (16 weeks) and follow-up (28 weeks). Clinical outcomes include time to recovery from major depressive episode (primary), depressive symptoms, PTSD symptoms and time to recovery from PTSD. Additional outcomes include social support, social role functioning (including parental functioning for those with living children), well-being, grief (including complicated grief and fault beliefs) and fear of subsequent pregnancies. Social support and grief are hypothesised mediators of IPT effects on time to recovery from major depressive episode.Ethics and disseminationThe trial was approved by Michigan State University’s Biomedical Institutional Review Board. It has a data and safety monitoring board and has been submitted to the community-based organisation partners community ethics review board. Written operating procedures outline methods for protecting confidentiality, monitoring and recording adverse events, and safeguarding participants. We will share study results with research and clinical communities, community organisations through which we recruited, and will offer results to study participants. Deidentified datasets will be available through the National Institute of Mental Health Data Archive and to qualified investigators on request.Trial registration numberNCT04629599.
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Weil, Joyce. "PLACE AND MEANING OF HOME: RESEARCH IN A VIRTUAL, PHOTOVOICE LENS." Innovation in Aging 6, Supplement_1 (November 1, 2022): 246. http://dx.doi.org/10.1093/geroni/igac059.976.
Повний текст джерелаАнотація:
Abstract Photovoice is built upon the principle of empowerment. With the increased use of Smartphones, photovoice provides a more readily available qualitative option for co-research with older adults. This presentation provides examples from the current study illustrating the process of creating a project that uses photovoice to see how older adults construct the meaning of home and place. While the benefits of this design are many, some issues do arise during implementation, such as: creating study protocols to address Institutional Review Board (IRB) concerns; working with organizations to ensure that the design is truly co-created; and navigating and conducting photovoice in a completely virtual arena. Examples will also be drawn from technical training received as part of LeadingAge LTSS Center @UMass Boston and Collective Insight’s Aging Centered Outcomes Research Learning Collaborative, as well as the Healthier Black Elders Center, which is affiliated with the University of Michigan and Wayne State University.
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Zenger Hain, Julie, Sarah Mange, Janice Bach, Debra Duquette, Jennifer McLosky, Lindsay Dohany, Jacquelyn Roberson, et al. "Assessment of cancer screening practices after BRCA testing in Michigan." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 1557. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.1557.
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1557 Background: Women who harbor BRCA1/2 mutations are at increased risk for breast and ovarian cancer and are advised to undergo high risk surveillance and/or preventative surgery. The compliance with screening guidelines in these women is not well known. This study aims to evaluate the uptake and screening practices of women with known deleterious BRCA mutations and BRCA true negatives who received genetic counseling in the state of Michigan. Methods: A telephone survey coordinated by the Michigan Department of Community Health was conducted on pts seen at 8 genetics clinics between 10/07 to 10/09. Each center was staffed by board certified genetics professionals who provided pre and post-test genetic counseling. Pts who were found to carry a deleterious BRCA mutation, or to be negative for a known familial mutation, were queried regarding adherence to NCCN guidelines. Results: 138 of 253 (55%) pts responded to the phone survey, with an elapsed time of 1.7 to 4.6 years from post-test counseling session. Among BRCA mutation carriers over age 25 years with no cancer history or mastectomy, 11 of 21 pts (52%) adhered to MRI screening guidelines, 3 pts (14%) reported two MRIs, and 7 (33%) pts had no MRI screening in the preceding year. 18 of 21 pts (86%) reported having a screening mammogram in the preceding year and the remaining 3 had two or more. 8 of 20 (40%) pts had two clinical breast exams. Of the women who had breast cancer and no mastectomy, 5 of 9 (56%) pts did not have MRI screening. Of the BRCA true negatives with no cancer history, CA-125 or transvaginal ultrasound was performed in 7 (19%) and 8 (20%) of 37 pts, respectively. Conclusions: This study reveals sub-optional compliance with screening guidelines in women who were identified to be carriers of BRCA mutations or those who were true negatives, despite pre and post-test genetic counseling and communication of established management guidelines. Some recommended screening measures were under-utilized in BRCA mutation carriers, and some were over-utilized in the true negatives. Additional interventions are needed to improve adherence to evidence-based screening guidelines aimed at promoting early detection, with an emphasis on appropriate utilization of limited healthcare resources.
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Smith, Robert. "Reviewer Acknowledgements." Journal of Education and Training Studies 5, no. 12 (November 29, 2017): 237. http://dx.doi.org/10.11114/jets.v5i12.2826.
Повний текст джерелаАнотація:
Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 5, Number 12Anne M. Hornak, Central Michigan University, USAAntónio Calha, Polytechnic Institute of Portalegre, PortugalAubri Rote, University of North Carolina at Asheville, USACagla Atmaca, Pamukkale University, TurkeyErica D. Shifflet-Chila, Michigan State University, USAFatma Ozudogru, Usak University, TurkeyIntakhab Khan, King Abdulaziz University, Saudi ArabiaIoannis Syrmpas, University of Thessaly, GreeceJohn Bosco Azigwe, Bolgatanga Polytechnic, GhanaJohn Cowan, Edinburgh Napier University, UKKatya De Giovanni, University of Malta, MaltaLaima Kyburiene, Kaunas University of Applied Sciences, LithuaniaLinda J. Rappel, Yorkville University/University of Calgary, CanadaLisa Marie Portugal, Grand Canyon University, USALorna T. Enerva, Polytechnic University of the Philippines, PhilippinesMarcie Zaharee, The MITRE Corporation, USAMarco Antonio Catussi Paschoalotto, University of São Paulo, BrazilMaria Pavlis Korres, Hellenic Open University, GreeceMatthews Tiwaone Mkandawire, Central China Normal University, MalawiMaurizio Sajeva, Pellervo Economic Research PTT, FinlandMehmet Inan, Marmara University, TurkeyMeral Seker, Alanya Alaaddin Keykubat University, TurkeyMichail Kalogiannakis, University of Crete, GreeceMin Gui, Wuhan University, ChinaMu-hsuan Chou, Wenzao Ursuline University of Languages, TaiwanMustafa Uğraş, Fırat University, TurkeyNele Kampa, Leibniz-Institute for Science and Mathematics Education (IPN), GermanyPhil Sirinides, University of Pennsylvania, USAPuneet S. Gill, Texas A&M International University, USARichard H. Martin, Mercer University, USASamad Mirza Suzani, Islamic Azad University, IranSelloane Pitikoe, University of Kwazulu-Natal, South AfricaSimona Savelli, Università degli Studi Guglielmo Marconi, ItalySisi Chen, American University of Health Sciences, USAStamatis Papadakis, University of Crete, GreeceSuzan Kavanoz, Yıldız Technical University, TurkeyThomas K. F. Chiu, The University of Hong Kong, Hong KongTilanka Chandrasekera, Oklahoma State University, USAVeronica Rosa, University Rome, ItalyYerlan Seisenbekov, Kazakh National Pedagogical University, Kazakhstan Robert SmithEditorial AssistantOn behalf of,The Editorial Board of Journal of Education and Training StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://jets.redfame.com
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Kulkarni, Roshni, Laura Carlson, Rebecca A. Malouin, Marcia L. Bird, Colleen Vallad-Hix, Michelle Witkop, Ajovi Scott-Emuakpor, Renuka Gera, and Steve Gualdoni. "Telehematology: Expanding Comprehensive Care for Pediatric Patients with Blood Disorders through Telemedicine at Several Delivery Sites (Medical Homes, Hospital Clinics, Home Setting and Hemophilia Treatment Centers (HTC)) and with Interdisciplinary Providers." Blood 126, no. 23 (December 3, 2015): 5576. http://dx.doi.org/10.1182/blood.v126.23.5576.5576.
Повний текст джерелаАнотація:
Abstract Background: Telemedicine (TM) is the exchange of medical information from one site to another via electronic communications to improve patients' health status and access to care. We used telemedicine to provide comprehensive hematology services to patients with blood disorders at a variety of sites that included medical homes, hospital specialty clinics, HTC, patients home and teleconsultation with out of state HTC, all located at a distance from the Michigan State University Center for Bleeding and Clotting Disorders (MSU CBCD). The goals were to increase access to family centered and culturally competent specialty care and increase the numbers of patients with blood/bleeding/clotting disorder that were timely and accurately diagnosed, managed and referred for specialty care. Objectives: 1) To understand the feasibility of telemedicine between specialists and a variety of remote sites for children with bleeding/blood disorders 2) To assess the acceptability by patients, families, primary care physicians, remote site staff, specialist physicians, and specialist staff and 3) To assess the cost of telemedicine visits versus traditional visits from the societal perspective 4) To provide education and resources to distant providers. Methods: Telemedicine sites were 1) two medical homes-one at a pediatrician's office, Upper Great Lakes Family Health Center (UGLFHC)/Portage Health in Houghton MI and the other at a family medicine office, Iron Mountain/Iron River Upper Peninsula, MI 2) specialty clinics at Marquette General Hospital, Marquette MI 3) Hemophilia Treatment Centers (HTC) at Traverse City MI and Rush University IL 4) and a patient's home in MI. PolycomTM and/or VidyoTM systems were used to deliver HIPAA (Health Insurance Portability and Accountability Act) regulated bidirectional videoconferencing technology. Records of patient visits seen by local providers and via TM by MSU CBCD pediatric hematologists, nurse and social worker were obtained. Data included patient diagnosis, distance traveled, estimated time and travel costs saved, and education of distance provider. Measurable objectives included feasibility, acceptability. Technology issues were addressed. Site visits with Portage and Iron River Health Department were conducted to discuss local barriers and needs. Results: Beginning 1998, a total of 68 patients, ages 2 weeks to 17 years and their families were seen by TM at various sites. There were 97 TM visits and frequency of clinics varied monthly to as needed. Average distance travelled by patients to local clinics ranged from 12 - 70 miles (range 2-170 miles). In addition to coagulation disorders (hemophilia, von Willebrands disease, factor deficiencies, patients with bleeding symptoms such as epistaxis, menorrhagia etc.), other diagnosis such as cytopenias, spherocytosis, hemoglobinopathies, lymphadenopathy, Hereditary Hemorrhagic Telangiectasia, Ehlers Danlos Syndrome, and pediatric oncology patients in follow-up phase were also seen and in some cases family members tested. Physician and staff were educated regarding disease management; guidelines and educational materials shared. Estimated costs per patients to fly or drive to MSUCBCD were $999 ($579 -$1275) and $1653 ($1405-1887) respectively compared to obtaining care locally $87.6 ($73-117) via TM. This resulted in cost savings per patient of $911.4 and $1565.7 for driving and flying respectively. The MSU CBCD team also incurred significant cost savings by avoiding travel/lodging costs. Interviews with staff and physicians resulted in improvement in TM acceptance and delivery. A majority of laboratory testing were send-outs and local testing for platelet function defects were not available. Technology issues addressed included adjustments in bandwidth, firewall and network settings. It was feasible to do consultations with out-of-state HTCs as well as follow patients at home. Conclusion: Besides improving access to specialty care, TM with remote areas is feasible and acceptable in a variety of settings with considerable time and cost savings for both patients as well as the specialty care treatment team. Our study is in accordance with the American Academy of Pediatrics recent policy statement (Pediatrics 2015;136:202-209) recommending that TM services be coordinated through the medical homes thereby involving local primary care providers. Disclosures Kulkarni: Biogen: Research Funding, Speakers Bureau; Baxter: Membership on an entity's Board of Directors or advisory committees, Research Funding; Bayer: Membership on an entity's Board of Directors or advisory committees, Research Funding; Novo Nordisk: Membership on an entity's Board of Directors or advisory committees, Research Funding, Speakers Bureau; Pfizer: Membership on an entity's Board of Directors or advisory committees; Kedrion: Membership on an entity's Board of Directors or advisory committees; BPL: Membership on an entity's Board of Directors or advisory committees. Witkop:Pfizer: Other: Advisory Board, Research Funding; Baxter Bioscience: Other: Advisory Board; Novo Nordisk: Other: Advisory Board, Speakers Bureau.
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Smith, Robert. "Reviewer Acknowledgements." Journal of Education and Training Studies 6, no. 1 (January 2, 2017): 169. http://dx.doi.org/10.11114/jets.v6i1.2908.
Повний текст джерелаАнотація:
Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 6, Number 1Brenda L. Shook, National University, USACagla Atmaca, Pamukkale University, TurkeyCarole Fern Todhunter, The University of Nottingham, UKCharlotte Alverson, University of Oregon, USAChosang Tendhar, Long Island University (LIU), USAEnisa Mede, Bahcesehir University, TurkeyErica D. Shifflet-Chila, Michigan State University, USAGreg Rickwood, Nipissing University, CanadaHyesoo Yoo, Virginia Tech., USAIoannis Syrmpas, University of Thessaly, GreeceJohn Cowan, Edinburgh Napier University, UKLinda J. Rappel, Yorkville University/University of Calgary, CanadaMan-fung Lo, The Hong Kong Polytechnic University, Hong KongMassimiliano Barattucci, Ecampus University, ItalyMaurizio Sajeva, Pellervo Economic Research PTT, FinlandMehmet Inan, Marmara University, TurkeyMichail Kalogiannakis, University of Crete, GreeceMin Gui, Wuhan University, ChinaNerina Fernanda Sarthou, Universidad Nacional del Centro de la Provincia de Buenos Aires, ArgentinaPirkko Siklander, University of Lapland, FinlandRichard H. Martin, Mercer University, USARichard Penny, University of Washington Bothell, USARiyadh Tariq Kadhim Al-Ameedi, Babylon University, IraqRufaidah Kamal Abdulmajeed, Baghdad University, IraqSadia Batool, Preston University Islamabad, PakistanSelloane Pitikoe, University of Kwazulu-Natal, South AfricaSenem Seda Şahenk Erkan, Marmara University, TurkeySeyyedeh Mina Hamedi, Ferdowsi University of Mashhad, IranSisi Chen, American University of Health Sciences, USATilanka Chandrasekera, Oklahoma State University, USAYalçın Dilekli, Aksaray University, TurkeyYerlan Seisenbekov, Kazakh National Pedagogical University, KazakhstanYi Lu, American Institute for Research, USAYuChun Chen, Louisiana Tech University, USARobert SmithEditorial AssistantOn behalf of,The Editorial Board of Journal of Education and Training StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://jets.redfame.com
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Wu, Felicia, Derek Headey, Kalle Hirvonen, Ashish Pokharel, and Masresha Tessema. "Study protocol to assess aflatoxin M1 health risks versus benefits of dairy consumption in Ethiopian children: an epidemiological trial and risk-benefit analysis." BMJ Open 14, no. 4 (April 2024): e084257. http://dx.doi.org/10.1136/bmjopen-2024-084257.
Повний текст джерелаАнотація:
IntroductionIn Sidama, Ethiopia, animal-source foods can be difficult to access. Milk has important nutrients for child growth, but carries the risk of aflatoxin M1(AFM1) contamination. AFM1is a metabolite of the mycotoxin aflatoxin B1(AFB1) in dairy feed; cows secrete AFM1in milk when their feed contains AFB1produced byAspergillusfungi in maize, nuts and oilseeds. It is unknown whether AFM1compromises child growth and health.Methods and analysisThis protocol paper describes our study in Sidama to determine the impact of milk consumption and AFM1on child growth in the first 18 months of life. We will collect baseline and end-line data on dairy production, socioeconomic and nutritional factors of 1000 dairy-owning households with children ages 6–18 months at baseline; and gather samples of milk and dairy feed and child anthropometrics. We will conduct phone interviews every 6 months to ascertain changes in practices or child health. Dairy feed will be tested for AFB1; milk for AFM1, pathogens and nutrients. Controlling for herd size, socioeconomic, nutritional and behavioural factors, we will determine the association between child anthropometrics and milk consumption, as well as AFM1exposure. We will examine whether AFM1exposure affects child growth in the first 18 months of life, and weigh the benefits and risks of milk consumption.Ethics and disseminationThe protocol is approved by the Institutional Review Boards of the Ethiopian Public Health Institute (EPHI-IRB-481–2022), Michigan State University (STUDY00007996) and International Food Policy Research Institute (DSGD-23–0102). Written informed consent will be obtained from all participants, who may withdraw from the study at any time. Confidentiality of collected data will be given high priority during each stage of data handling. The study’s findings will be disseminated through stakeholder workshops, local and international conferences, journal articles and technical reports.
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Ondersma, Steven J., Lisa Todd, Samantha Jablonski, Chaarushi Ahuja, Kathryn Gilstad-Hayden, Gregory Goyert, Amy Loree, Jaimee Heffner, and Kimberly A. Yonkers. "Online randomised factorial trial of electronic Screening and Brief Intervention for alcohol use in pregnancy: a study protocol." BMJ Open 12, no. 8 (August 2022): e062735. http://dx.doi.org/10.1136/bmjopen-2022-062735.
Повний текст джерелаАнотація:
IntroductionApproximately 1 in 7 pregnant women in the USA report past-month alcohol use. Strong evidence connects prenatal alcohol exposure with a range of adverse perinatal outcomes, including the spectrum of conditions known as fetal alcohol spectrum disorders. Screening and Brief Intervention (SBI) has been recommended for pregnant women but has proven difficult to implement. This study will test the efficacy of single-session technology-delivered SBI (electronic SBI) for alcohol use in pregnancy, while simultaneously evaluating the possible additional benefit of tailored text messages and/or booster sessions in a 3×2 factorial trial.Method and analysisThis full factorial trial will use online advertising and clinic-based flyers to recruit pregnant women meeting criteria for unhealthy alcohol use, and randomly assign them to one of six conditions crossing three levels of brief intervention (none, single 120-minute session and single session plus two 5-minute boosters) with two levels of tailored text messaging (none vs twice weekly messages). The primary analysis will test for dose–response effects of the brief intervention on alcohol abstinence, defined as no self-report of alcohol use in the 90 days prior to 34 weeks’ gestation, and negative results for ethyl glucuronide analysis of fingernail samples. Secondary analyses will examine main and interaction effects of tailored text messaging as well as intervention effects on birth outcomes.Ethics and disseminationEthical approval was provided by the Michigan State University Biomedical and Health Institutional Review Board (STUDY00005298). Results will be presented at conferences and community forums, in addition to being published in a peer-reviewed journal. Intervention content demonstrating sufficient efficacy and safety will be made publicly available.Trial registration numberClinicalTrials.gov Registry (NCT04332172).
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Levendosky, Alytia Akiko, G. Anne Bogat, Joseph Lonstein, Maria Muzik, and Amy K. Nuttall. "Longitudinal prospective study examining the effects of the timing of prenatal stress on infant and child regulatory functioning: the Michigan Prenatal Stress Study protocol." BMJ Open 11, no. 9 (September 2021): e054964. http://dx.doi.org/10.1136/bmjopen-2021-054964.
Повний текст джерелаАнотація:
IntroductionA considerable literature implicates prenatal stress as a critical determinant of poor psychological functioning in childhood and beyond. However, knowledge about whether the timing of prenatal stress differentially influences the development of child outcomes, including psychopathology, is virtually unknown. The primary aim of our study is to examine how the timing of prenatal stress differentially affects early childhood regulatory functioning as a marker of psychopathology. Our second aim is to examine the mediating effects of maternal physiological and psychological factors during pregnancy. Our third aim is to examine the moderating effects of postnatal factors on child regulatory functioning. Our project is the first longitudinal, prospective, multimethod study addressing these questions.Methods and analysisOur ongoing study recruits pregnant women, oversampled for intimate partner violence (a common event-based stressor allowing examination of timing effects), with data collection starting at pregnancy week 15 and concluding 4 years post partum. We aim to have n=335 mother–child dyads. We conduct a granular assessment of pregnancy stress (measured weekly by maternal report) in order to reveal sensitive periods during fetal life when stress particularly derails later functioning. Pattern-based statistical analyses will be used to identify subgroups of women who differ in the timing of their stress during pregnancy and then test whether these patterns of stress differentially predict early childhood self-regulatory outcomes.Ethics and disseminationDue to the high-risk nature of our sample, care is taken to ensure protection of their well-being, including a safety plan for suicidal ideation and a safety mechanism (exit button in the online weekly survey) to protect participant data privacy. This study was approved by Michigan State University Institutional Review Board. Dissemination will be handled by data sharing through National Institute of Child Health and Human Development Data and Specimen Hub (DASH), as well as through publishing the findings in journals spanning behavioural neuroendocrinology to clinical and developmental psychology.
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Kim, Lindsay, Bryanna Cikesh, Pam Daily Kirley, Evan J. Anderson, Seth Eckel, Kathryn Como-Sabetti, Elizabeth M. Dufort, et al. "746. Characteristics of Respiratory Syncytial Virus (RSV) Infection Among Hospitalized Adults, United States, 2014–2017." Open Forum Infectious Diseases 5, suppl_1 (November 2018): S268. http://dx.doi.org/10.1093/ofid/ofy210.753.
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Abstract Background Respiratory syncytial virus (RSV) vaccines are in clinical development for older adults. We described RSV infections among adults requiring hospitalization and risk factors for severe outcomes using a population-based platform, the Influenza Hospitalization Surveillance Network (FluSurv-NET). Methods Surveillance occurred October 1–April 30 (2014–2017) at sites located in seven states (California, Georgia, Michigan, Minnesota, New York, Oregon, and Tennessee) covering an annual catchment population of up to 13 million adults ≥18 years. Laboratory-confirmed RSV cases were identified using hospital and state public health laboratories, hospital infection preventionists, and/or reportable condition databases. Medical charts were reviewed for demographic and clinical data. International Classification of Diseases (ICD) discharge codes were abstracted. Odds ratios (Oregon) and 95% confidence intervals (CIs) were determined to assess risk factors for ICU hospitalization and deaths. Results A total of 2,326 hospitalized RSV cases were identified. Over half were ≥65 years (62%, n = 1,438/2,326), female (59%, n = 1,362/2,326), white (70%, n = 1,301/1,855), and had ≥3 underlying medical conditions (52%, n = 1,204/2,326). 20% (n = 398/2,000) were hospitalized in the ICU (median length of stay, 3 days; interquartile range, 1–6 days), and 5% (n = 96/2,001) died in the hospital. Congestive heart failure (CHF; OR: 1.4, 95% CI: 1.1–1.8) and chronic obstructive pulmonary disease (COPD; OR: 1.3, 95% CI: 1.1–1.7) were associated with ICU admission, while age ≥80 years (OR: 4.1, 95% CI: 1.8–12.1) and CHF (OR: 2.4, 95% CI: 1.6–3.6) were associated with in-hospital deaths. RSV-specific ICD codes were listed in the first 9 positions in only 44% (879/1,987) of cases. Conclusion To our knowledge, this is the largest US case series of RSV-infected hospitalized adults. Most cases were ≥65 years and had multiple underlying medical conditions. Older age, CHF, and COPD were associated with the most severe outcomes. Few cases had RSV-specific ICD codes, suggesting that administrative data underestimate adult RSV-related hospitalizations. Continued surveillance is needed to understand the epidemiology of RSV among adults as vaccine products move toward licensure. Disclosures E. J. Anderson, NovaVax: Grant Investigator, Research grant. Pfizer: Grant Investigator, Research grant. AbbVie: Consultant, Consulting fee. MedImmune: Investigator, Research support. PaxVax: Investigator, Research support. Micron: Investigator, Research support. H. K. Talbot, sanofi pasteur: Investigator, Research grant. Gilead: Investigator, Research grant. MedImmune: Investigator, Research grant. Vaxinnate: Safety Board, none. Seqirus: Safety Board, none.
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Ramo, Aula, Harshita Mehrotra, Ifeoma Onwubiko, Jawad Sheqwara, and Zaher K. Otrock. "Correlation between ABO Blood Groups and Disease Severity and Mortality in Hospitalized COVID-19 Patients." Blood 136, Supplement 1 (November 5, 2020): 43–44. http://dx.doi.org/10.1182/blood-2020-141688.
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Introduction After appearance of the novel Coronavirus 2019 in Wuhan, China, new epicenters of the now pandemic appeared nationally. The new Coronavirus disease 2019 (COVID-19) is associated with a syndrome of acute hypoxemic respiratory failure that can lead to admission to intensive care unit (ICU), invasive mechanical ventilation, and at times, death. The first two COVID-19 cases in the State of Michigan were reported in March 10, 2020. During the subsequent weeks, Michigan became one of the early national epicenters of the current COVID-19 pandemic. Early observational studies have suggested a correlation between susceptibility to COVID-19 infection and type A blood group, and furthermore, increased risk of respiratory failure and worse outcome. We conducted this retrospective study to evaluate the association between ABO blood groups and disease severity/mortality in hospitalized COVID-19 patients. Methods We reviewed the records of hospitalized patients with PCR-confirmed COVID-19 testing managed at Henry Ford Health System (HFHS) between March 10 and April 30, 2020. Henry Ford Health System (HFHS) serves inner city and metropolitan Detroit in Michigan, with diverse demographics including African American, Middle Eastern, and Caucasian populations. Age, gender, race, ABO blood groups, comorbidities, disease severity (defined as intensive care unit admission), intubation, and mortality variables were collected for 1488 eligible patients. Survival data was updated on July 15, 2020. Results were presented as median plus range, or percentages as indicated. In the univariate analysis, Student's t-test and Pearson's Chi-square/Fisher's exact test were used to determine the significance and odds ratio (OR) for the independent variables as related to outcome. A multivariate analysis was performed using logistic regression to identify the risk factors for mortality. A backward stepwise (Wald) selection model was performed, with significance level for removal from the model set at 0.1. All tests of significance were two-sided, and a p value of < 0.05 was regarded as significant. All statistical analyses were performed using SPSS (Statistical Package for Social Sciences) software, version 22 (SPSS Inc., Chicago, IL, USA). This study was approved by the Institutional Review Board of HFHS. Results 1488 hospitalized COVID-19 positive patients with available ABO blood group were included. The median age of patients was 68 years (Range 19-99 years); 801 (54%) were females. Most patients (n=856; 58%) were African Americans. 485 (32.6%) patients had blood group A, 276 (18.5%) had group B, 658 (44.2%) had group O, and 69 (4.6%) had group AB. 469 (31.5%) patients required ICU admission, 370 of whom were intubated. On last follow up, 411 (27.6%) patients were dead. ABO blood groups and Rhesus factor (D antigen) were not associated with the ICU admission, intubation, or mortality. Male gender, age ≥65 years, some underlying diseases such as obesity, coronary artery disease chronic obstructive pulmonary disease and malignancy were associated with increased mortality. African American patients were almost 40% less likely to die (OR = 0.56; 95% CI: 0.44-0.7; p < 0.001). Table 1 shows the parameters analyzed as predictors of mortality using univariate and multivariate logistic regression. Multivariate analysis showed that age (≥65 years) (OR = 4.27; 95% CI: 3.19-5.71; p < 0.001), male gender (OR = 1.57; 95% CI: 1.23-2.01; p < 0.001), Caucasian race (OR=1.46; 95% CI: 1.14-1.86; p = 0.003), and COPD (OR = 1.49; 95% CI: 1.09-2.04; p = 0.013) were associated with mortality. Conclusion According to our study, ABO blood groups and Rhesus factor did not correlate with disease severity, use of mechanical ventilation, or mortality in hospitalized COVID-19 patients. Elderly patients, male gender, patients with COPD were at increased risk of death. Contrary to perceived belief, African Americans were not at increased risk of mortality, compared to Caucasians with COVID-19 infection. Caucasians were more likely to die from COVID-19 infection. Disclosures No relevant conflicts of interest to declare.
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Abel, Gregory A., Ann Vanderplas, Jonathan W. Friedberg, Joyce Niland, Maria A. Rodriguez, Myron S. Czuczman, Michael Millenson, et al. "Variations in Surveillance Imaging for Patients with Treated Diffuse Large B-Cell Lymphoma in the National Comprehensive Cancer Network (NCCN) Lymphoma Database." Blood 114, no. 22 (November 20, 2009): 1387. http://dx.doi.org/10.1182/blood.v114.22.1387.1387.
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Abstract Abstract 1387 Poster Board I-409 BACKGROUND: Utility and optimal timing of surveillance imaging for patients with treated diffuse large B-cell lymphoma (DLBCL) remains uncertain, especially in the era of positron emission tomography. METHODS: Data were obtained from the NCCN Non-Hodgkin's Lymphoma Outcomes Database, a prospective cohort study collecting comprehensive clinical, treatment, and outcome data for patients seen at 7 participating NCCN centers. Patients who presented between January 1, 2001 and June 30, 2007 with a new diagnosis of DLBCL in remission for at least three months after the completion of initial therapy were eligible for this study. For those patients with at least two years of follow-up, we assessed overall number and modality of imaging studies performed starting 90 days after the end date of their first-line therapy until documented relapse or end of two-year follow-up window. We then created three subcategories depending upon surveillance strategy: “PET” = positron emission tomography scans or combined positron emission tomography/limited computed tomography scans only; “CT”= computed tomography scans only; or “BOTH PET AND CT” = combination of both “PET” and “CT” at different times. For those who relapsed after being in primary remission for at least 90 days, we assessed the nature of the visit where relapse was first documented, recent accompanying imaging, and the presence of a confirmatory biopsy within one month before or after that relapse. RESULTS: As of July 1, 2009, 433 newly-diagnosed DLBCL patients had at least two years of follow-up from 6 of the 7 participating NCCN centers; median age was 56 and 57% were male. Initial stage and International Prognostic Index (IPI) were as follows: I = 24%; II= 24%; III= 16%; IV=36%; and low= 47%; low-intermediate= 26%; high-intermediate= 19% and high= 8%. For surveillance imaging as defined above, 14% received PET, 48% received CT, and 38% received BOTH PET AND CT. Range of median frequencies across NCCN centers are reported below, both overall and by test type. Overall median number of tests received per year differed significantly across NCCN centers (p for Kruskal-Wallis < 0.0001). Of 990 patients in primary remission for at least 90 days, there were 108 (11%) documented relapses. Of those, 20% were found at non-routine visits with symptoms, 41% at routine visits with symptoms, 37% at routine visits without symptoms and 2% were unclear. Of those found at routine visits without symptoms, 73% had undergone imaging within one month before and up to the date of relapse. Finally, 77% of those with relapse underwent confirmatory biopsy within one month before or after relapse. CONCLUSIONS: The frequency of surveillance imaging for patients with treated DLBCL is highly variable, even within the context of tertiary care academic centers. Despite controversy surrounding its use, a high proportion of DLBCL patients in remission are followed with PET modalities. Those being followed exclusively with PET modalities tend to have less frequent imaging, which may have implications for comparative effectiveness. Routine imaging likely identifies relapse in about a quarter of patients with DLBCL; the impact on ultimate outcome remains to be further evaluated. Disclosures: Friedberg: Genentech: Membership on an entity's Board of Directors or advisory committees. Blayney: American Society of Clinical Oncology: Membership on an entity's Board of Directors or advisory committees; BlueCross Blue Shield of Michigan: Research Funding; NCCN: Honoraria; University of Michigan Health System: Employment.
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Robbins, Lorraine B., Jiying Ling, Karin A. Pfeiffer, Jean M. Kerver, Kenneth Resnicow, Harlan McCaffery, Aisha Hilliard, Logan Hobbs, Sheldon Donald, and Niko Kaciroti. "Intervention to increase physical activity and healthy eating among under-represented adolescents: GOAL trial protocol." BMJ Open 14, no. 1 (January 2024): e080437. http://dx.doi.org/10.1136/bmjopen-2023-080437.
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IntroductionTo reduce obesity-related disparities, reaching economically disadvantaged and/or minority status adolescents to assist them in meeting physical activity (PA) and nutrition recommendations is important. To address the problem, a 16-week intervention called Guys/Girls Opt for Activities for Life (GOAL) was designed. The purpose of this randomised controlled trial is to evaluate any effect of the intervention, compared with a control condition, on improving: (1) adolescents’ % body fat (primary outcome), moderate-to-vigorous PA (MVPA), diet quality and cardiorespiratory fitness from 0 to 4 months; (2) body mass index (BMI), overweight/obesity percentage and quality of life from 0 to 4 months and to 13 months; and (3) perceived social support, self-efficacy and motivation from 0 to 4 months with evaluation of any mediating effect on adolescent PA and diet quality. An exploratory aim is to evaluate any effect of the intervention, compared with the control, on improving parents’/guardians’ home environment, MVPA and diet quality from 0 to 4 months; and BMI from 0 to 4 months and to 13 months.Methods and analysisAdolescents (fifth to eighth grade) in 14 schools located in underserved urban communities are randomly assigned to the intervention or usual school offerings. One parent per adolescent is enrolled (882 dyads total). Cohort 1 includes four schools (2022–2023). Cohorts 2 and 3 include 5 schools in 2023–2024 and 2024–2025, respectively. The 16-week intervention has three components: (1) after-school GOAL club for adolescents to engage in PA and healthy eating/cooking activities; (2) three parent–adolescent meetings to empower parents to assist adolescents; and (3) GOAL social networking website for parents to share how they helped their adolescent.Ethics and disseminationThe Michigan State University Biomedical Institutional Review Board provided ethical approval for the study. Findings will be shared via the trial registration database, peer-reviewed publications, conferences and community-oriented strategies.Trial registration numberNCT04213014.
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Funk, Julie A., and Paul C. Bartlett. "Public Health Education at Michigan State University." Journal of Veterinary Medical Education 35, no. 2 (June 2008): 199–202. http://dx.doi.org/10.3138/jvme.35.2.199.
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Jagannath, Sundar, Jesus G. Berdeja, Robert M. Rifkin, Craig E. Cole, Michael Alan Thompson, Ravi Vij, Mihaela Popa-McKiver, Rao Saleem, Oumar Sy, and William Bensinger. "Elotuzumab Plus Pomalidomide and Dexamethasone for Relapsed/Refractory Multiple Myeloma: Initial Data from a Phase 2, Non-Comparative Study." Blood 132, Supplement 1 (November 29, 2018): 1991. http://dx.doi.org/10.1182/blood-2018-99-112077.
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Abstract Introduction: Despite therapeutic advances, most patients (pts) with multiple myeloma (MM) eventually develop relapsed/refractory (RR) disease, and observational studies of pts refractory to immunomodulatory drugs and proteasome inhibitors have demonstrated a median overall survival (OS) of 13 mo (Kumar et al, Leukemia 2017;31:2443-8). Elotuzumab, an immunostimulatory monoclonal antibody targeted to SLAMF7, directly activates natural killer cells and mediates the killing of MM cells through antibody-dependent cellular cytotoxicity and antibody-dependent cellular phagocytosis. Elotuzumab, combined with lenalidomide (len) and dexamethasone (dex), is indicated in the USA and EU for RRMM in pts who have received ≥1 prior therapy. Pomalidomide (pom), a 2nd-generation immunomodulatory drug, appears to synergize with elotuzumab. The phase 2, randomized, international, exploratory ELOQUENT-3 study (NCT02654132) assessed elotuzumab combined with pom and dex (EPd) vs pom and dex (Pd); after a minimum follow-up of 9 mo, median progression-free survival (PFS) with EPd was 10.3 vs 4.7 mo with Pd (hazard ratio=0.54) and the overall response rate (ORR) was 53% vs 26% (Dimopoulos et al, EHA 2018 [LB2606]). In this supportive study, with a minimum follow-up of 16 mo, we present initial efficacy and safety data for EPd in pts with relapsed and/or refractory MM. Methods: This phase 2, multicenter, non-comparative study (NCT02612779) enrolled pts ≥18 y of age with MM who were relapsed, refractory, or intolerant to len (received for ≥2 consecutive cycles), 1-2 prior therapies, disease progression during or after their last therapy, and with an Eastern Cooperative Oncology Group performance status of ≤2. Prior pom was not permitted. Pts received elotuzumab 10 mg/kg IV weekly for the first two 28-d cycles and 20 mg/kg IV every 4 wk thereafter. Pom 4 mg orally was given on Days 1-21 of each cycle and dex 40 or 20 mg oral equivalent was given weekly for pts ≤75 or >75 y of age, respectively. Primary endpoint was PFS; additional endpoints included OS, ORR, and safety. Results: At database lock (Apr 4, 2018), 68 pts had received EPd. At baseline, median age was 67 y, 35 pts (51%) were male, and 21 (31%) had International Staging System stage II-III disease. Median (range) prior number of therapies was 2 (1-5) and 34 pts (50%) were relapsed and refractory to their most recent therapy; 6 pts had received ≥3 prior therapies. Prior therapies included len (n=68, 100%), bortezomib (n=59, 87%), cyclophosphamide (n=20, 29%), carfilzomib (n=14, 21%), and autologous stem cell transplantation (n=38, 56%). At analysis, pts had received a median of 9 cycles of EPd and 13 (19%) were still on treatment. The most common reasons for discontinuation were disease progression (n=26, 38%) and maximum clinical benefit (n=10, 15%). Median PFS was 11.1 mo (Figure) and ORR was 51%. Overall, 9 pts (13%) achieved very good partial response or better, 26 (38%) achieved partial response, and 12 (18%) achieved minimal response. Median (95% CI) duration of response was 16.7 (11.3, not estimable [NE]) mo. Median time to first response was 1 mo, and to best response was 2.8 mo. Median (95% CI) OS was 22.4 (21.8, NE) mo. Pts with ≥2 prior therapies had a median (95% CI) PFS of 11.1 (5.6, 15.0) mo and an ORR of 46%. The most frequent all-cause non-hematologic adverse events (AEs) were fatigue (n=37, 54%), diarrhea (n=23, 34%), and upper respiratory tract infection (n=23, 34%); all-cause infections were reported in 47 pts (69%). No second primary malignancies were reported. The most common all-cause hematologic AE was neutropenia, reported in 24 pts (35%) and grade 3-4 in 11 (16%). Anemia was reported in 15 pts (22%) and was grade 3-4 in 4 (6%). Infusion reactions were reported in 5 pts (7%), all grade 1-2. In total, 7 pts (10%) experienced grade 5 AEs, 1 of which (pulmonary sepsis) was considered related to treatment. Overall, 11 pts (16%) experienced AEs leading to discontinuation. Conclusions: EPd was associated with a median PFS of 11.1 mo and ORR of 51% in pts with RRMM. Safety was consistent with prior reports of elotuzumab and pom, with no new safety signals. These data, coupled with findings from the randomized ELOQUENT-3 study, support EPd as a new, effective treatment option for pts with RRMM. Study support: BMS. Medical writing: Adam Gill, Caudex, funded by BMS Disclosures Jagannath: Merck: Consultancy; Bristol-Myers Squibb: Consultancy; Novartis: Consultancy; Celgene: Consultancy; Multiple Myeloma Research Foundation: Speakers Bureau; Medicom: Speakers Bureau. Berdeja:Teva: Research Funding; Glenmark: Research Funding; Amgen: Research Funding; Novartis: Research Funding; Takeda: Research Funding; Bristol-Myers Squibb: Research Funding; Celgene: Research Funding; Genentech: Research Funding; Janssen: Research Funding; Bluebird: Research Funding; Poseida Therapeutics, Inc.: Research Funding; Sanofi: Research Funding. Rifkin:Celgene: Consultancy; EMD Serono: Consultancy; Takeda: Consultancy; Sandoz: Consultancy; McKesson: Equity Ownership; Boehringer Ingelheim: Consultancy; Amgen: Consultancy. Cole:University of Michigan: Employment; Cancer Support Community myeloma advisory board: Membership on an entity's Board of Directors or advisory committees. Thompson:Syapse Precision Medicine Council: Other: Member; Strata Oncology: Membership on an entity's Board of Directors or advisory committees; VIA Oncology: Other: Co-Chair Medical Hematology ITP Committee, Co-Chair Medical Oncology Indolent Lymphoma Committee; Plasma Cell Dyscrasias: Patents & Royalties: Peer Review for Plasma Cell Dyscrasias (Editor: Robert Kyle); Glaxosmith Kline: Membership on an entity's Board of Directors or advisory committees; Takeda: Other: Multiple Myeloma Registry; AIM Specialty Health: Membership on an entity's Board of Directors or advisory committees; Celgene: Other: Connect MDS/AML Registry - Scientific Steering Committee Member. Vij:Celgene: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Takeda: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Bristol-Myers Squibb: Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Karyopharma: Honoraria, Membership on an entity's Board of Directors or advisory committees; Jansson: Honoraria, Membership on an entity's Board of Directors or advisory committees; Amgen: Honoraria, Membership on an entity's Board of Directors or advisory committees; Jazz Pharmaceuticals: Honoraria, Membership on an entity's Board of Directors or advisory committees. Popa-McKiver:Bristol-Myers Squibb: Employment. Saleem:Bristol-Myers Squibb: Employment. Sy:Bristol-Myers Squibb: Employment. Bensinger:Janssen: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda: Speakers Bureau; Amgen: Speakers Bureau; Celgene: Membership on an entity's Board of Directors or advisory committees, Speakers Bureau.
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Walton, Edward A., Ronald F. Maio, and Elizabeth M. Hill. "Camp Health Services in the State of Michigan." Wilderness & Environmental Medicine 15, no. 4 (December 2004): 274–83. http://dx.doi.org/10.1580/1080-6032(2004)015[0274:chsits]2.0.co;2.
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Solway, Erica. "Involvement in State and Federal Aging Policy." Innovation in Aging 4, Supplement_1 (December 1, 2020): 684. http://dx.doi.org/10.1093/geroni/igaa057.2385.
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Abstract The fourth speaker is Dr. Erica Solway. Dr. Solway will discuss her experience working in policy at the federal level as a Health and Aging Policy Fellow and a policy advisor with the U.S. Senate Committee on Health, Education, Labor, and Pensions Subcommittee on Primary Health and Aging and in her current involvement in policy-relevant research at the state and national level at the University of Michigan Institute for Healthcare Policy & Innovation. Dr. Solway is a senior project manager forthe evaluation of the Healthy Michigan Plan, Michigan’s Medicaid expansion program, and is also an associate director of the University of Michigan National Poll on Healthy Aging.
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Malloy, Mary. "Growing a State Society: The Michigan Model." Journal of Oncology Practice 1, no. 3 (September 2005): 115. http://dx.doi.org/10.1200/jop.2005.1.3.115.
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Malloy, M. "Growing a State Society: The Michigan Model." Journal of Oncology Practice 1, no. 3 (September 1, 2005): 115. http://dx.doi.org/10.1200/jop.1.3.115.
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Brenneise, Harvey R., and Ellen B. Marks. "Creating a state‐wide virtual health library: the Michigan experience." Online Information Review 25, no. 2 (April 2001): 115–20. http://dx.doi.org/10.1108/14684520110390051.
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Levy, Helen, John Z. Ayanian, Thomas C. Buchmueller, Donald R. Grimes, and Gabriel Ehrlich. "Macroeconomic Feedback Effects of Medicaid Expansion: Evidence from Michigan." Journal of Health Politics, Policy and Law 45, no. 1 (October 15, 2019): 5–48. http://dx.doi.org/10.1215/03616878-7893555.
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Abstract Context: Medicaid expansion has costs and benefits for states. The net impact on a state's budget is a central concern for policy makers debating implementing this provision of the Affordable Care Act. How large is the state-level fiscal impact of expanding Medicaid, and how should it be estimated? Methods: We use Michigan as a case study for evaluating the state-level fiscal impact of Medicaid expansion, with particular attention to the importance of macroeconomic feedback effects relative to the more straightforward fiscal effects typically estimated by state budget agencies. We combine projections from the state of Michigan's House Fiscal Agency with estimates from a proprietary macroeconomic model to project the state fiscal impact of Michigan's Medicaid expansion through 2021. Findings: We find that Medicaid expansion in Michigan yields clear fiscal benefits for the state, in the form of savings on other non-Medicaid health programs and increases in revenue from provider taxes and broad-based sales and income taxes through at least 2021. These benefits exceed the state's costs in every year. Conclusions: While these results are specific to Michigan's budget and economy, our methods could in principle be applied in any state where policy makers seek rigorous evidence on the fiscal impact of Medicaid expansion.
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Arsen, David, Tanner Delpier, Annie Gensterblum, Rebecca Jacobsen, and Alexandra Stamm. "Rural communities need better state education policies." Phi Delta Kappan 103, no. 4 (December 2021): 8–13. http://dx.doi.org/10.1177/00317217211065820.
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The specific needs of rural schools and communities have received limited attention from state policy makers, and many state programs have only added to the challenges that school districts in rural areas face. Michigan State University researchers surveyed and interviewed rural superintendents in Michigan to learn more about their situations. Superintendents identified teacher recruitment and retention, the need for mental health services, limited broadband access, and insufficient funding as their most pressing challenges. The researchers note that addressing these challenges will require state leaders to pay specific attention to rural needs and develop rural-conscious education policies.
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Brenneise, Harvey R. "Steps in Developing a State-Wide Digital Health Library in Michigan." Journal of Hospital Librarianship 2, no. 4 (September 2002): 49–59. http://dx.doi.org/10.1300/j186v02n04_04.
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Chen, Xinguang, Bin Yu, Bonita Stanton, Robert L. Cook, Ding-Geng(Din) Chen, and Chukwuemeka Okafor. "Medical Marijuana Laws and Marijuana Use Among U.S. Adolescents: Evidence From Michigan Youth Risk Behavior Surveillance Data." Journal of Drug Education 48, no. 1-2 (March 2018): 18–35. http://dx.doi.org/10.1177/0047237918803361.
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Research findings are inconsistent regarding a positive association between the passage of state medical marijuana laws (MML) and the adolescent access and the use of marijuana. We utilized a novel analytical approach to examine this issue with multiyear data from the 1997–2013 Youth Risk Behavior Surveillance System of the State of Michigan. After controlling for the historically declining trend in marijuana use prior to the passages of MML in Michigan, we found that marijuana use among adolescents had increased subsequent to the passage of state MML. The study findings suggest the need for considering the increased risk of marijuana use in adolescents, as more states have implemented laws permitting marijuana use.
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Crimmins, Eileen. "Margret M. and Paul B. Baltes Award Lecture: Optimism and Health: Resource or Delusion?" Innovation in Aging 5, Supplement_1 (December 1, 2021): 404. http://dx.doi.org/10.1093/geroni/igab046.1567.
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Abstract The lecture will be given by the 2020 Baltes Award recipient, William Chopik, PhD, of Michigan State University. The recipient of the 2021 Baltes Award is Laura B. Zahodne, PhD, of the University of Michigan. The Margret M. and Paul B. Baltes Foundation Award in Behavioral and Social Gerontology recognizes outstanding early-career contributions in behavioral and social gerontology. The award is generously funded by the Margret M. and Paul B. Baltes Foundation.
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Leeb, Karen, Denise Chrysler, and Richard A. Goodman. "The Social Distancing Law Project Template: A Method for Jurisdictions to Assess Understanding of Relevant Legal Authorities." Disaster Medicine and Public Health Preparedness 4, no. 1 (March 2010): 74–80. http://dx.doi.org/10.1017/s1935789300002457.
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ABSTRACTMethods: The Centers for Disease Control and Prevention and the Association of State and Territorial Health Officials selected 17 state and large local jurisdictions on the basis of their proximity to federal quarantine stations and collaborated with their state health department legal counsel to conduct formulaic self-assessments of social distancing legal authorities, create tables of authority, and test and report on the laws' sufficiency (ie, scope and breadth). Select jurisdictions also held tabletop exercises to test public health and law enforcement officials' understanding and implementation of pertinent laws. This report presents findings for Michigan, which completed the legal assessment and tabletop exercise and made several recommendations for change as a result.Results: Officials in Michigan concluded that there are sufficient existing laws to support social distancing measures but that a spectrum of questions remained regarding implementation of these legal authorities. Based on the findings of this assessment, Michigan initiated actions to address areas for improvement.Conclusions: The results of this project highlighted the value of integrally involving the state health department's legal counsel—those most familiar with and who advise on a given state's public health laws—in the periodic identification, assessment, and testing of the state's legal authorities for social distancing and other measures used in response to many public health emergencies.(Disaster Med Public Health Preparedness. 2010;4:74-80)
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Shakthy, Esha. "Effect of E-Cigarette Tax on Health Outcomes." Cornell Undergraduate Research Journal 2, no. 2 (December 21, 2023): 14–30. http://dx.doi.org/10.37513/curj.v2i2.735.
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The alarming rise in the use of electronic cigarettes (e-cigarettes) among teens in the US has become a major health concern, driving many states to take action, including Illinois, which implemented a 15% tax on e-cigarettes. This research aims to evaluate the effectiveness of taxation to control e-cigarette use, measured by improvement in health outcomes in Illinois, from before and after the state implemented the 15% tax. Additionally, a comparison was done with neighboring states of Michigan and Missouri. Using difference-in-difference hypothesis testing, a statistically significant decrease in reported rates of asthma, depression, toothache, and bleeding gums, was noted when comparing health outcomes before and after the implementation of the state tax in Illinois as compared to Michigan. A decrease in the reported rate of asthma was noted to be significant in the comparison with Missouri as well.
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Hunt, Jennifer, and Alexis Travis. "Lessons On Using Health Research & Technology To Broaden Resources For Older Adults Across The State." Innovation in Aging 5, Supplement_1 (December 1, 2021): 97. http://dx.doi.org/10.1093/geroni/igab046.366.
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Abstract The vision of the Michigan state unit on aging is for residents to live well and thrive as they age. The COVID-19 pandemic exacerbated the existing problem of older adult social isolation. Social engagement and community involvement are keys to healthy aging. Combining state resources with the GetSetUp virtual community allowed for statewide connections and extended resources, creating an almost around-the-clock virtual senior center. Through customized courses the state was able to offer vaccine navigation sign-up classes, among other classes, to help older adults interact with essential health and aging services. As Michigan continues to work to address health equity and social determinants of health beyond the pandemic, technology designed specifically for older adults is an important component of programmatic offerings. It also allows for a public-private partnership opportunity to support older adults as they age.
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Chandra, Siddharth, Julia Christensen, Madhur Chandra, and Nigel Paneth. "Pandemic Reemergence and Four Waves of Excess Mortality Coinciding With the 1918 Influenza Pandemic in Michigan: Insights for COVID-19." American Journal of Public Health 111, no. 3 (March 2021): 430–37. http://dx.doi.org/10.2105/ajph.2020.305969.
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The global influenza pandemic that emerged in 1918 has become the event of reference for a broad spectrum of policymakers seeking to learn from the past. This article sheds light on multiple waves of excess mortality that occurred in the US state of Michigan at the time with insights into how epidemics might evolve and propagate across space and time. We analyzed original monthly data on all-cause deaths by county for the 83 counties of Michigan and interpreted the results in the context of what is known about the pandemic. Counties in Michigan experienced up to four waves of excess mortality over a span of two years, including a severe one in early 1920. Some counties experienced two waves in late 1918 while others had only one. The 1920 wave propagated across the state in a different manner than the fall and winter 1918 waves. The twin waves in late 1918 were likely related to the timing of the statewide imposition of a three-week social distancing order. Michigan’s experience holds sobering lessons for those who wish to understand how immunologically naïve populations encounter novel viral pathogens.
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Spiroff, Meghan, Patricia Piechowski, Karen D. Calhoun, Susan Goold, Ayse Buyuktur, Michael Klinkman, Elias M. Samuels, Zachary Rowe, and Zachary Rowe. "2438 Community-based research networks: Providing infrastructure for clinical and translational research in the State of Michigan." Journal of Clinical and Translational Science 2, S1 (June 2018): 65–66. http://dx.doi.org/10.1017/cts.2018.241.
Повний текст джерелаАнотація:
OBJECTIVES/SPECIFIC AIMS: As the sole Clinical and Translational Science Award (CTSA) site in Michigan, the Michigan Institute for Clinical & Health Research (MICHR) at the University of Michigan (UM) is working to develop community networks that drive clinical and translational research on community-identified health priorities. METHODS/STUDY POPULATION: These CBRNs will be modeled from successful work that has been accomplished in Jackson, MI where stakeholders from the local healthcare community, County Health Department, Health Improvement Organization, and grassroots community members created a Community of Solution to address the unmet behavioral health and social needs of community members. The CBRN’s will focus on identifying community health priorities by receiving input from community members in underserved communities using deliberative software called Choosing All Together (CHAT). RESULTS/ANTICIPATED RESULTS: In the fall of 2017, 3 focus groups were held in Northern Michigan to identify community health priorities. The top 5 community health priorities include; (1) mental wellness, (2) long-term illness, (3) alcohol and drugs, (4) air, water, and land, and (5) affording care. Additional focus groups are scheduled for the winter in 2 additional geographic areas. DISCUSSION/SIGNIFICANCE OF IMPACT: Future work for the creation of CBRNs includes building leadership groups comprised of clinicians, community leaders, public health leaders, health system leaders and researchers to inform the leadership groups of community-identified health priorities. In addition, the team is working to identify a platform to connect academic investigators across UM and community partners on shared research priorities in real time. In order to measure and map relationships within the networks, we are planning to utilize Social Network Analysis as an evaluation tool.
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Whitten, Pamela, and Jill Rowe-Adjibogoun. "Success and failure in a Michigan telepsychiatry programme." Journal of Telemedicine and Telecare 8, no. 3_suppl (December 2002): 75–77. http://dx.doi.org/10.1258/13576330260440943.
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summary Telemedicine programmes are often complex undertakings that result in combinations of success and failure. Michigan State University and LifeWays received a grant for a four-phase telepsychiatry research project in 2000. We employed multiple data-collection techniques, including patient and provider surveys, in-depth interviews, observation, patient chart analyses, and organizational archival data analyses. Of the four phases in the project, two proved to be successful, one failed in its initial goal but succeeded with a redefined goal, and one failed completely. Issues that affected success or failure included human resource conflicts, organizational structure, inter-organizational relationships and allocated resources.
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Burt, S. Alexandra, and Kelly L. Klump. "The Michigan State University Twin Registry (MSUTR): An Update." Twin Research and Human Genetics 16, no. 1 (October 29, 2012): 344–50. http://dx.doi.org/10.1017/thg.2012.87.
Повний текст джерелаАнотація:
The primary aim of the Michigan State University Twin Registry (MSUTR) is on understanding developmental changes in genetic, environmental, and neurobiological influences on internalizing and externalizing disorders, with antisocial behavior and disordered eating representing our particular areas of interest. The MSUTR has two broad components: a large-scale, population-based registry of child, adolescent, and adult twins and their families (current N ~20,000) and a series of more focused and in-depth studies drawn from the registry (current N ~4,000). Participants in the population-based registry complete a family health and demographic questionnaire via mail. Families are then recruited for one or more of the intensive, in-person studies from the population-based registry based on their answers to relevant items in the registry questionnaire. These in-person assessments target a variety of biological, genetic, and environmental phenotypes, including multi-informant measures of psychiatric and behavioral phenotypes, census and neighborhood informant reports of twin neighborhood characteristics, buccal swab and salivary DNA samples, assays of adolescent and adult steroid hormone levels, and/or videotaped interactions of child twin families. This article provides an overview of the MSUTR and describes current and future research directions.
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Weston, Andrea L., and Kyle S. Enger. "Factors Associated with Hepatitis A Vaccination Receipt in One-Year-Olds in the State of Michigan." Journal of Biomedicine and Biotechnology 2010 (2010): 1–7. http://dx.doi.org/10.1155/2010/360652.
Повний текст джерелаАнотація:
The objectives of this study were to determine factors associated with hepatitis A vaccination and to assess overall hepatitis A vaccination coverage levels among one-year-olds in Michigan. The study population was the first hepatitis A vaccination-eligible birth cohort (n=134 226) enrolled in the Michigan Care Improvement Registry (MCIR) after 2006 recommendations were made to routinely vaccinate all one-year-olds. All children whose first birthday occurred on or between May 1, 2006 and April 31, 2007 were included in the study population. Racial/ethnic minorities had increased odds of receiving the hepatitis A vaccination in Michigan, and Medicaid and WIC status modified this relationship. Fully understanding these relationships will be useful in targeting vaccination outreach and education programs.
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MacQuillan, Elizabeth, Amy Curtis, Kathleen Baker, and Rajib Paul. "Geospatial Analysis of Birth Records to Target Programming for Mothers With Gestational Diabetes Mellitus in Michigan, 2013." Public Health Reports 134, no. 1 (December 6, 2018): 27–35. http://dx.doi.org/10.1177/0033354918815183.
Повний текст джерелаАнотація:
Objectives: The incidence of gestational diabetes mellitus (GDM) in the United States has increased during the past several decades. The objective of this study was to use birth records and a combination of statistical and geographic information system (GIS) analyses to evaluate GDM rates among subgroups of pregnant women in Michigan. Materials and Methods: We obtained data on maternal demographic and health-related characteristics and regions of residence from 2013 Michigan birth records. We geocoded (ie, matched to maternal residence) the birth data, calculated proportions of births to women with GDM, and used logistic regression models to determine predictors of GDM. We calculated odds ratios (ORs) from the exponentiated beta statistic of the logistic regression test. We also used kernel density estimations and local indicators of spatial association (LISA) analyses to determine GDM rates in regions in the state and identify GDM hot spots (ie, areas with a high GDM rate surrounded by areas with a high GDM rate). Results: We successfully geocoded 104 419 of 109 168 (95.6%) births in Michigan in 2013. Of the geocoded births, 5185 (5.0%) were to mothers diagnosed with GDM. LISA maps showed a hot spot of 8 adjacent counties with high GDM rates in southwest Michigan. Of 11 064 births in the Southwest region, 829 (7.5%) were to mothers diagnosed with GDM, the highest rate in the state and a result confirmed by geospatial analyses. Practice Applications: Birth data and GIS analyses may be used to measure statewide pregnancy-associated disease risk and identify populations and geographic regions in need of targeted public health and maternal–child health interventions.
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Shumway, Dean A., Kent A. Griffith, Lori J. Pierce, Mary Feng, Jean M. Moran, Matthew H. Stenmark, Reshma Jagsi, and James A. Hayman. "Wide Variation in the Diffusion of a New Technology: Practice-Based Trends in Intensity-Modulated Radiation Therapy (IMRT) Use in the State of Michigan, With Implications for IMRT Use Nationally." Journal of Oncology Practice 11, no. 3 (May 2015): e373-e379. http://dx.doi.org/10.1200/jop.2014.002568.
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Heller, Rafael. "Big money and its influence on K-12 education: An interview with Sarah Reckhow." Phi Delta Kappan 99, no. 8 (April 30, 2018): 41–45. http://dx.doi.org/10.1177/0031721718775677.
Повний текст джерелаАнотація:
Kappan’s editor talks with Michigan State University’s Sarah Reckhow about her research into the ways wealthy private philanthropies have influenced K-12 education in recent years. As Reckhow explains, not only have Gates, Broad, Walton, and other big foundations spent unprecedented amounts of money to support their favored reform strategies — such as expanding the charter school sector, raising academic standards, and evaluating teachers’ effectiveness — but they’ve maximized their influence by coordinating their messages, funneling their money to specific states and districts, pushing for changes in state and federal policy, and (most recently) contributing to local school board candidates.
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Chrysler, Denise, Harry McGee, Janice Bach, Ed Goldman, and Peter D. Jacobson. "The Michigan BioTrust for Health: Using Dried Bloodspots for Research to Benefit the Community While Respecting the Individual." Journal of Law, Medicine & Ethics 39, S1 (2011): 98–101. http://dx.doi.org/10.1111/j.1748-720x.2011.00577.x.
Повний текст джерелаАнотація:
The Michigan Department of Community Health (MDCH) stores almost 4 million dried blood spot specimens (DBS) in the Michigan Neonatal Biobank. DBS are collected from newborns under a mandatory public health program to screen for serious conditions. At 24 to 36 hours of age, a few drops of blood are taken from the baby’s heel and placed on a filter paper card. The card is sent to the state public health laboratory for testing. After testing, MDCH retains the spots indefinitely for the personal use of the patient and also, pursuant to a 2000 law, for possible research.
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Nathan, Vincent R. "Drinking water in Michigan: source, quality, and contaminants." Journal of Water and Health 4, S1 (July 1, 2006): 67–73. http://dx.doi.org/10.2166/wh.2006.0045.
Повний текст джерелаАнотація:
The Michigan Safe Drinking Water Act (Act 399) was enacted in 1976 and enables the Michigan Department of Environmental Quality (DEQ) to maintain the state's authority over drinking water in the state. The DEQ also contracts with local health departments to maintain non-community programs in each county. Private water wells throughout the state are clearly the most troublesome for users and regulators. An abundant array of contaminants (e.g., pesticides, metals, etc.) may impact wells without the user's knowledge. Most private wells are only inspected when they are installed and have no further regulatory requirements. With regards to contaminants in public systems, lead is problematic. Irregardless of the source or treatment, the piping infrastructure leading to and inside the home can be a source affecting the quality. Thus, the problem of lead in drinking water can be from the service lines, the pipes inside the home, the solder connecting the pipes, or in some case the treatment chemicals used for disinfection.
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Fleck, Leonard, and Arthur Ward. "Altruistic Organ Donation: On Giving a Kidney to a Stranger." Cambridge Quarterly of Healthcare Ethics 31, no. 3 (July 2022): 395–99. http://dx.doi.org/10.1017/s0963180121001080.
Повний текст джерелаАнотація:
AbstractIn the following interview, philosophers Leonard Fleck and Arthur Ward discuss the latter’s recent experience of being a nondirected kidney donor. The interview took place in the Center for Bioethics and Social Justice at Michigan State University.
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Hayman, James, Kent A. Griffith, Reshma Jagsi, Mary Uan-Sian Feng, Jean M. Moran, Tania L. Piotrowski, and Lori J. Pierce. "Variation in the use of intensity-modulated radiation therapy (IMRT) in the state of Michigan: 2005-2010." Journal of Clinical Oncology 30, no. 34_suppl (December 1, 2012): 219. http://dx.doi.org/10.1200/jco.2012.30.34_suppl.219.
Повний текст джерелаАнотація:
219 Background: Interest is growing in value in health care, defined as better outcomes at lower costs. A primary driver of cost in radiation oncology is the use of IMRT. We examined the patterns and correlates of use of IMRT across Michigan using publicly available data. Methods: As a certificate of need state, Michigan requires every radiation oncology facility to report yearly the number of external beam and IMRT treatments delivered. Data for 2005-2008 were obtained through a Freedom of Information Act request of the Michigan Department of Community Health, while 2009-2010 data were available at its website. Percentage of external beam treatments delivered using IMRT (IMRT%) was examined across centers over time and repeated-measures longitudinal linear regression was used to identify factors associated with use. Results: During 2005-2010, 48 to 65 centers reported data. Median IMRT% (range) rose steadily during the study period: 2005 16% (0-64); 2006 21% (0-57); 2007 27% (0-79); 2008 37% (7-85); 2009 41% (0-87) 2010 45% (7-100). There was also significant between-center variation (see table). Regression modeling demonstrated that IMRT% was associated with year (+6.7% per year, p<0.0001), facility type (+7.1% freestanding versus hospital, p<0.11), facility annual volume (+5.0% high volume: 7,000+ versus low: <7,000, p=0.01) and the interaction between year and volume (low volume +2.4% per year versus high volume p<0.02). The significant interaction between year and volume suggests that the greatest IMRT% growth was in low volume centers (6.7% per year versus 4.3% per year for high volume). Conclusions: IMRT utilization has grown steadily across Michigan between 2005 and 2010. There is significant variation in its use that appears to be related in part to facility characteristics. The newly established Michigan Radiation Oncology Quality Collaborative (MROQC) is beginning to explore the use of IMRT in patients with breast and lung cancer statewide to identify those groups of patients where improved outcomes may justify its higher cost. [Table: see text]
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Hillemeier, Craig, Jose Cara, Jay Berkelhamer, and Jean Robillard. "State-Wide Managed Care Plan for the Children's Special Health Care Population in Michigan." Pediatric Research 45, no. 4, Part 2 of 2 (April 1999): 125A. http://dx.doi.org/10.1203/00006450-199904020-00743.
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Dean, Caress A. "Social Determinants of Health Associated With Michigan Residents 50 Years and Older Health-Related Quality of Life and Cardiovascular Health." Gerontology and Geriatric Medicine 6 (January 2020): 233372142097983. http://dx.doi.org/10.1177/2333721420979834.
Повний текст джерелаАнотація:
Objective: Studies show perceived health-related quality of life (HRQL) is associated with cardiovascular health (CVH) status; however, there is a limited understanding of underlying determinants of the CVH and HRQL of adults ≥50 years. Therefore, this study’s objective was to examine social determinants of health (SDOH) associated with Michigan residents ≥50 years HRQL measures and CVH status. Methods: Michigan-level data was extracted from the 2017 Behavioral Risk Factor Surveillance System to complete the study’s objective. The data were weighted to obtain state-level estimates. Multinomial and binary logistic regression analyses identified SDOH significantly associated with Michiganders ≥50 years CVH status and HRQL measures. Results: The sample consisted of 10,889 participants. Compared to residents with a moderate CVH and mental health status, residents who reported unable to visit a doctor due to costs were two times more likely than those who were able to visit a provider to have a non-ideal CVH and mental health status (OR = 2.65; 95% CI: 1.39–5.07). Discussion: SDOH were significantly associated with non-ideal CVH and HRQL measures. Interventions that seek to address the CVH and perceive HRQL of residents ≥50 years should also address their underlying SDOH. Research should be performed to determine the generalizability of these findings.
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Kerekeș, Ștefania Szeibert. "CASE STUDY: MICHIGAN'S RESPONSE TO THE COVID-19 PANDEMIC." Cluj University Journal. Interdisciplinary: Social Sciences and Humanities 1, no. 1 (November 15, 2023): 98–114. http://dx.doi.org/10.61846/cuji-ssh.1.1.07.
Повний текст джерелаАнотація:
The development of health policies is a very difficult task, especially when we have an ongoing pandemic and there are many factors that must be considered to develop these policies. The present article analyzes the actions of the State of Michigan in the United States (US) during the SARS-CoV-2 pandemic in comparison with the policies applied in Romania, member of the European Union (EU). By observing the strategies applied, we can deduce the degree of effectiveness of policies in both areas. The study period chosen is the year between 2020-2021 because this is the time frame when most policies were introduced globally. This research paper brings to the light the detailed analysis of health policies, highlighting effective strategies in pandemic management and comparing health policies between the EU and the US, focusing on Romania and the State of Michigan.
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Stobierski, Mary Grace, Kimberly Signs, Emily Dinh, Thomas M. Cooley, Julie Melotti, Michele Schalow, Jon S. Patterson, Steven R. Bolin, and Edward D. Walker. "Eastern Equine Encephalomyelitis in Michigan: Historical Review of Equine, Human, and Wildlife Involvement, Epidemiology, Vector Associations, and Factors Contributing to Endemicity." Journal of Medical Entomology 59, no. 1 (November 4, 2021): 27–40. http://dx.doi.org/10.1093/jme/tjab153.
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Abstract Eastern equine encephalomyelitis (EEE) is a mosquito-borne viral disease that is an emerging public health concern in the state of Michigan. Although Michigan has one of the highest incidence rates of EEE in the United States, much of the information known about cases in humans, equines, and other animals residing in Michigan is unpublished. This article summarizes such information and explores spatial trends in the historic distribution of EEE in Michigan. Outbreaks in Michigan have occurred over an 80-yr interval, involving only horses in 1942–1943 and 1973–1976, and then episodically from 1980 to 2020, and involving horses, humans, and wild and domestic animals. An estimated 1,036 equine cases (confirmed and suspected) and 36 confirmed human cases have occurred, including 10 in 2019 (6 deaths) and 4 in 2020 (2 deaths). Human cases ranged in age from 1 to 81 yr; 70% were male, and fatality rate of 34.3%. Equine and human cases occurred from July to October, peaked in August, and cluster in space in southwestern and southeastern lower Michigan. Cases occurred in glacial outwash and ice-contact landscapes in glacial interlobate zones. EEE virus (EEEV) was recovered from Culiseta melanura, Coquillettidia perturbans, five species of Aedes, and other mosquito species near horse and human case sites. Virus isolations or presence of neutralizing antibodies in several passerine species of birds suggest broad EEEV–bird associations. White-tailed deer and other wildlife were also affected. Geographic spread to northern areas of the state suggests expansion of this disease system into new and unsuspected foci.
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Anda, Robert F., Dennis L. Dodson, David F. Williamson, and Patrick L. Remington. "Health Promotion Data for State Health Departments: Telephone versus in-Person Survey Estimates of Smoking and Alcohol Use." American Journal of Health Promotion 4, no. 1 (September 1989): 32–36. http://dx.doi.org/10.4278/0890-1171-4.1.32.
Повний текст джерелаАнотація:
During 1988, more than 40 state health departments conducted telephone surveys to obtain state-specific population estimates of the prevalence of adult health behaviors and health practices. However, the comparability of estimates obtained from these telephone surveys with more expensive in-person surveys has not been assessed in an applied setting. This study compared the prevalence estimates of smoking and binge drinking obtained from a telephone survey (N = 1,492) with an in-person survey (N = 2,802) which were conducted by the state of Michigan during 1982–1983. Although the standard errors for the differences in the estimates for the two surveys were relatively large, the actual differences were consistently small within most age-, sex-, and education-specific groups. Despite certain limitations, telephone surveys provide a reasonable alternative to in-person surveys for estimating the prevalence of health behaviors. The data obtained from these surveys are being used to set state health objectives, to plan statewide health promotion programs, and to support public health legislation.
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White, Jeffrey A., Xuguang Tao, Milan Talreja, Jack Tower та Edward Bernacki. "The Effect of Opioid Use on Workersʼ Compensation Claim Cost in the State of Michigan". Journal of Occupational and Environmental Medicine 54, № 8 (серпень 2012): 948–53. http://dx.doi.org/10.1097/jom.0b013e318252249b.
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McKnight, Kevin P., Joseph P. Messina, Ashton M. Shortridge, Meghan D. Burns, and Bruce W. Pigozzi. "Using Volunteered Geographic Information to Assess the Spatial Distribution of West Nile Virus in Detroit, Michigan." International Journal of Applied Geospatial Research 2, no. 3 (July 2011): 72–85. http://dx.doi.org/10.4018/jagr.2011070105.
Повний текст джерелаАнотація:
West Nile Virus is a vector-borne flavivirus that affects mainly birds, horses, and humans. The disease emerged in the United States in 1999 and by 2001 had reached Michigan. In clinical human cases, the most common symptoms are fever, weakness, nausea, headache, and changes in mental state. The crow is the most common wildlife host in the life cycle of the virus. The state of Michigan, through the Michigan Department of Community Health, collected the spatial locations of over 8,000 dead birds (Corvidae), statewide, during 2002. The large number of samples made spatial and temporal hotspot detection possible. However, the volunteer reporting method produced a dataset with a direct correlation between the numbers and locations of the dead birds and human population density and accurately identifying hotspots remains a challenge. Geographic variation in dead bird intensity was modeled using both global and local spatial clustering algorithms. Statistical models identified overall spatial structure and local clustering. Identification of hotspots was confounded by limited information about the collection procedures, data availability and quality, and the limitations of each method.
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Delva, Jorge, Adam Paberzs, Patricia Piechowski, Karen Calhoun, Diane Carr, Meghan Spiroff, Ayse Buyuktur, and Kevin Weatherwax. "2543." Journal of Clinical and Translational Science 1, S1 (September 2017): 54. http://dx.doi.org/10.1017/cts.2017.193.
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OBJECTIVES/SPECIFIC AIMS: To describe how Michigan Institute for Clinical & Health Research (MICHR) has engaged communities in its leadership and governance structure. This presentation will describe these practices, how they are being evaluated, and future plans for institute-wide engagement of communities in translational research. METHODS/STUDY POPULATION: Engaged partners from various communities across Michigan in various ways within MICHR’s Community Engagement Program. RESULTS/ANTICIPATED RESULTS: MICHR has utilized participatory practices in the development of the CAB to strengthen existing relationships and build new ones with potential partners. DISCUSSION/SIGNIFICANCE OF IMPACT: MICHR-wide Community Advisory Board (CAB) will ensure community voices are heard and utilized in leadership and strategic decisions for CTSA activities.