Добірка наукової літератури з теми "Metabolomic chemistry"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Metabolomic chemistry".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Статті в журналах з теми "Metabolomic chemistry"
Delporte, Cédric, Nausicaa Noret, Cécile Vanhaverbeke, Olivier J. Hardy, Jean-François Martin, Marie Tremblay-Franco, David Touboul, et al. "Does the Phytochemical Diversity of Wild Plants Like the Erythrophleum genus Correlate with Geographical Origin?" Molecules 26, no. 6 (March 17, 2021): 1668. http://dx.doi.org/10.3390/molecules26061668.
Повний текст джерелаKim, Hyun Woo. "Metabolomic Approaches to Investigate the Effect of Metformin: An Overview." International Journal of Molecular Sciences 22, no. 19 (September 24, 2021): 10275. http://dx.doi.org/10.3390/ijms221910275.
Повний текст джерелаMeiliana, Anna, Nurrani Mustika Dewi, and Andi Wijaya. "Metabolomics: An Emerging Tool for Precision Medicine." Indonesian Biomedical Journal 13, no. 1 (March 1, 2021): 1–18. http://dx.doi.org/10.18585/inabj.v13i1.1309.
Повний текст джерелаSegers, Karen, Sven Declerck, Debby Mangelings, Yvan Vander Heyden, and Ann Van Eeckhaut. "Analytical techniques for metabolomic studies: a review." Bioanalysis 11, no. 24 (December 2019): 2297–318. http://dx.doi.org/10.4155/bio-2019-0014.
Повний текст джерелаTsuchida, Sachio, and Tomohiro Nakayama. "Metabolomics Research in Periodontal Disease by Mass Spectrometry." Molecules 27, no. 9 (April 30, 2022): 2864. http://dx.doi.org/10.3390/molecules27092864.
Повний текст джерелаKiseleva, Olga, Ilya Kurbatov, Ekaterina Ilgisonis, and Ekaterina Poverennaya. "Defining Blood Plasma and Serum Metabolome by GC-MS." Metabolites 12, no. 1 (December 24, 2021): 15. http://dx.doi.org/10.3390/metabo12010015.
Повний текст джерелаMain, Sawyer C., Lindsay P. Brown, Kelly R. Melvin, Shawn R. Campagna, Brynn H. Voy, Hector F. Castro, Lewrell G. Strickland, et al. "Metabolomic Profiles in Starved Light Breed Horses during the Refeeding Process." Animals 12, no. 19 (September 21, 2022): 2527. http://dx.doi.org/10.3390/ani12192527.
Повний текст джерелаPaganelli, Alessia, Valeria Righi, Elisabetta Tarentini, and Cristina Magnoni. "Current Knowledge in Skin Metabolomics: Updates from Literature Review." International Journal of Molecular Sciences 23, no. 15 (August 7, 2022): 8776. http://dx.doi.org/10.3390/ijms23158776.
Повний текст джерелаSatori, Chad P., Marzieh Ramezani, Joseph S. Koopmeiners, Audrey F. Meyer, Jose A. Rodriguez-Navarro, Michelle M. Kuhns, Thane H. Taylor, Christy L. Haynes, Joseph J. Dalluge, and Edgar A. Arriaga. "Checkpoints for preliminary identification of small molecules found enriched in autophagosomes and activated mast cell secretions analyzed by comparative UPLC/MSe." Analytical Methods 9, no. 1 (2017): 46–54. http://dx.doi.org/10.1039/c6ay02500e.
Повний текст джерелаMiettinen, Teemu, Anni I. Nieminen, Pekka Mäntyselkä, Eija Kalso, and Jörn Lötsch. "Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes." International Journal of Molecular Sciences 23, no. 9 (May 3, 2022): 5085. http://dx.doi.org/10.3390/ijms23095085.
Повний текст джерелаДисертації з теми "Metabolomic chemistry"
Pesko, Bogumila Katarzyna. "Estimation of time since death using comparative proteomic and metabolomic approaches." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8179/.
Повний текст джерелаWipulaguna, M. A. Anushika Shiromi. "Use of metabolomic studies to understand the chemical role of ETHE1 in Arabidopsis thaliana." Miami University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=miami1417604333.
Повний текст джерелаJaeger, Frederick Howard. "Simplified Plant Sample Preparation for use in Gas Chromatography-Mass Spectrometry (GC-MS) Based Metabolomic Profiling and Targeted Analyte Quantitation." NCSU, 2008. http://www.lib.ncsu.edu/theses/available/etd-02202008-155316/.
Повний текст джерелаTaraboletti, Alexandra Anna. "Chemical and Metabolomic Analyses of Cuprizone-Induced Demyelination and Remyelination." University of Akron / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=akron1498535047689141.
Повний текст джерелаVincent, Isabel May. "Using metabolomic analyses to study mode of action of and resistance to Eflornithine in Trypanosoma brucei." Thesis, University of Glasgow, 2011. http://theses.gla.ac.uk/3125/.
Повний текст джерелаThomas, Éric. "Stratégies de marquage chimiospécifique et bioorthogonale pour l’analyse métabolomique des rétinoïdes." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAF052.
Повний текст джерелаThis work consists of three projects. The first project aims to discover new metabolites of vitamin A. An analog of retinaldehyde, carrying an azide function was synthesized. It would allow to follow its fate in vivo. The second project consisted in the development of a probe allowing the analysis of all the aldehyde metabolites in a sample. The probe provides sensitivity gain in LS-MS². An analysis of its biodistribution has been done, and showed the ATPP probe is distributed after an intraperitoneal injection. Concerning the third project, a homobifunctional coupling reagent "thiol-to-thiol" has been developed. The coupling products showed excellent plasma stability. The reagent was first successfully applied to the coupling of small molecules and then to the coupling of a modified oligonucleotide and a peptide
Telo, Jasmin. "Conditioning of chromatographic systems prior to metabolomic studies : Investigation of the conditioning effect and the possibility to alter it." Thesis, Uppsala universitet, Avdelningen för analytisk farmaceutisk kemi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-324642.
Повний текст джерелаBentley, Joanne. "Comparative metabolomic profiling of phenolics in the desiccation-tolerant “resurrection plant” Myrothamnus flabellifolia (Myrothamnaceae) using conventional and green chemistry-based solvent systems." Doctoral thesis, Faculty of Science, 2019. http://hdl.handle.net/11427/30437.
Повний текст джерелаPorter, Sarah Elizabeth Graham. "Chemometric Analysis of Multivariate Liquid Chromatography Data: Applications in Pharmacokinetics, Metabolomics, and Toxicology." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/1156.
Повний текст джерелаZhang, Linwen. "Emerging Methods for Single Cell Metabolomics." Thesis, The George Washington University, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10746962.
Повний текст джерелаSingle cell metabolomics provides new insights into understanding cellular heterogeneity of small molecules, and individual cell response to environmental perturbations. With high sensitivity and specificity, mass spectrometry (MS) has become an important tool for analyzing metabolites, lipids, and peptides in individual cells. Facing significant challenges, single cell and subcellular analysis by MS requires technical advances to answer fundamental biological questions, for example the phenotypic variations of genetically identical cells. The work presented in this dissertation describes my efforts to develop and apply capillary microsampling MS with ion mobility separation (IMS) for the analysis of single cells and subcellular compartments.
Chapter 1 introduces MS based analytical techniques for single cell and subcellular analysis. Recent advances of sampling and ionization methods for MS analysis of volume-limited samples are reviewed with emphasis on ambient ionization techniques, cell micromanipulation methods, and rapid gas phase separations.
In Chapter 2, the application of capillary microsampling electrospray ionization (ESI)-IMS-MS for metabolic and lipidomic analysis of single Arabidopsis thaliana epidermal cells is presented. Distinct metabolite compositions and metabolic pathways are identified among basal and pavement cells, and trichomes. These three specialized epidermal cells serve different functions in the plant leaf, and our single cell MS data reveals the corresponding metabolic pathways.
In Chapter 3, it describes the utilization of capillary microsampling ESI-IMS-MS for the analysis of metabolites and lipids in single human hepatocellular carcinoma cells. Cellular physiological states and their heterogeneity in response to xenobiotics treatment, and lipid turnover rates are explored. Here, IMS helps to enhance molecular coverage, facilitate metabolite and lipid identification, resolve isobaric ions, and minimize background interference. Comparing cells affected by metabolic modulators to unaffected counterparts reveals dramatic reduction in the availability of energy in the former.
In Chapter 4, the combination of fluorescence microscopy with capillary microsampling ESI-IMS-MS for selective analysis of identified cell subpopulations at a single cell level is demonstrated. Molecular differences and heterogeneity corresponding to cells in distinct mitotic stages are explored. Pairwise correlations between relative metabolite levels among individual mitotic cells are also studied.
In Chapter 5, the subcellular distributions of neuropeptides in individual identified neurons are explored by capillary microsampling ESI-IMS-MS. Distinct peptide distributions between the cytoplasm and nucleus are revealed. Mass spectra provide direct evidence for high abundance of these peptides in the nucleus despite the scarcity of immunostaining results supporting their presence there. A new neuropeptide is discovered and sequenced by MS in a single cell.
In Chapter 6, the current state of single cell and subcellular metabolomics is discussed. Major challenges include the low-throughput of current sampling techniques, low molecular coverage of metabolites, lipids and peptides, and external perturbations introduced by the sampling and ionization processes. In addition to exploring new solutions to these challenges, future advances will lead to the development of systems biology at the single cell level, to nano- and micro-fabricated tools to study perturbations in a lab-in-a-cell framework, and to coupling with optical manipulations and microfluidic techniques to investigate subcellular heterogeneity.
Книги з теми "Metabolomic chemistry"
Processing Metabolomics and Proteomics Data with Open Software: A Practical Guide. Royal Society of Chemistry, The, 2020.
Знайти повний текст джерелаZhang, Aihua, Hui Sun, and Xijun Wang. Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine. Elsevier Science & Technology Books, 2015.
Знайти повний текст джерелаZhang, Aihua, Hui Sun, and Xijun Wang. Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine. Elsevier Science & Technology Books, 2015.
Знайти повний текст джерелаCastro-Puyana, María, Miguel Herrero, and María Luisa Marina, eds. Capillary Electrophoresis in Food Analysis. BENTHAM SCIENCE PUBLISHERS, 2022. http://dx.doi.org/10.2174/97898150361521220201.
Повний текст джерелаVignoli, Alessia, Gaia Meoni, and Leonardo Tenori, eds. Research in Metabolomics via Nuclear Magnetic Resonance Spectroscopy: Data Mining, Biochemistry and Clinical Chemistry. MDPI, 2022. http://dx.doi.org/10.3390/books978-3-0365-4554-7.
Повний текст джерелаЧастини книг з теми "Metabolomic chemistry"
Kim, Yun-Gon, and Alan Saghatelian. "Functional Analysis of Protein Targets by Metabolomic Approaches." In Topics in Current Chemistry, 137–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/128_2011_284.
Повний текст джерелаChristians, Uwe, Volker Schmitz, Jost Klawitter, and Jelena Klawitter. "Proteo-Metabolomic Strategies in the Future of Drug Development." In Analytical Techniques for Clinical Chemistry, 691–774. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2012. http://dx.doi.org/10.1002/9781118271858.ch24.
Повний текст джерелаMahadeo, Keshika, Isabelle Grondin, Hippolyte Kodja, Hermann Thomas, Patricia Clerc, Michel Frederich, and Anne Gauvin-Bialecki. "A Chemotaxonomic Study of 11 Species of the Genus Psiadia Endemic to La Reunion by 1H NMR and GC-MS Based Metabolomic Approach." In Chemistry for a Clean and Healthy Planet, 139–52. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-20283-5_9.
Повний текст джерелаJahangir, M., T. R. Nuringtyas, K. Ali, E. G. Wilson, Y. H. Choi, and R. Verpoorte. "CHAPTER 9. NMR-based Metabolomics: Understanding Plant Chemistry and Identification of Biologically Active Compounds." In NMR-based Metabolomics, 246–63. Cambridge: Royal Society of Chemistry, 2018. http://dx.doi.org/10.1039/9781782627937-00246.
Повний текст джерелаWeinberger, Klaus M., and Marc Breit. "Targeted Metabolomics: The Next Generation of Clinical Chemistry!" In Translational Bioinformatics, 175–211. Dordrecht: Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-7543-4_7.
Повний текст джерелаSingh, Rajveer, Robin Joshi, Eduardo D. Munaiz, Sanjay Kumar, and Arun Kumar. "Chapter 17. Application of Metabolomics to Food Systems." In Food Chemistry, Function and Analysis, 416–42. Cambridge: Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839163005-00416.
Повний текст джерелаRobards, Kevin. "Chapter 14. Metabolomics and the Measurement of Antioxidant Behavior." In Food Chemistry, Function and Analysis, 454–80. Cambridge: Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839165337-00454.
Повний текст джерелаRobards, Kevin. "Chapter 14. Metabolomics and the Measurement of Antioxidant Behavior." In Food Chemistry, Function and Analysis, 454–80. Cambridge: Royal Society of Chemistry, 2021. http://dx.doi.org/10.1039/9781839165337-00454.
Повний текст джерелаBervoets, L., and P. Adriaensens. "Chapter 8. Metabolomics in Nutritional Metabolism, Obesity, and Diabetes." In Food Chemistry, Function and Analysis, 210–36. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160608-00210.
Повний текст джерелаJones, Oliver A. H., and Helmut M. Hügel. "Bridging the Gap: Basic Metabolomics Methods for Natural Product Chemistry." In Methods in Molecular Biology, 245–66. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-577-4_18.
Повний текст джерелаТези доповідей конференцій з теми "Metabolomic chemistry"
González-Domínguez, Raúl, Álvaro González-Domínguez, and Alfonso Lechuga-Sancho. "Comparison of the metabolomic signature of diabetes and the oral glucose tolerance test." In 4th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2018. http://dx.doi.org/10.3390/ecmc-4-05571.
Повний текст джерелаNargoli, Javier, Hugo Cerecetto, Javier Varela, and Mercedez González. "Search of Trypanosomicidal Active Principles by Metabolomic-guided Fractionation in Baccharis trimera." In 3rd International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2017. http://dx.doi.org/10.3390/ecmc-3-04840.
Повний текст джерелаDudley, Ed, Robin Tuytten, Filip Lemiere, Eddy E. Esmans, and Russell P. Newton. "The bioanalysis of urinary modified nucleosides by mass spectrometry: their study as potential metabolomic biomarkers of cancer development." In XIVth Symposium on Chemistry of Nucleic Acid Components. Prague: Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810229.
Повний текст джерела