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Zare, Ghasem, Jaouad Alem, and Fatemeh Zare. "The validation of the measurement of the mental and physical components of SF-12 in Iranian elderly." SHS Web of Conferences 119 (2021): 01002. http://dx.doi.org/10.1051/shsconf/202111901002.
Повний текст джерелаАнотація:
This study aimed to assess the validity and reliability of the mental component summary (MCS) and physical component summary (PCS) of SF-12. 140 Iranian elderly aged 60 years and older from the general population (100 male vs 40 female) of the Shiraz city were recruited by convenient sampling. The questionnaire on quality of life (SF-12, two dimensions: the physical component α = 0.68; and the mental component α = 0.71) was used to collect the data analyzed with the AMOS software. According to the structural equation model (SEM), four subscales of SF-12 (emotional role, social function, vitality and mental health) can predict mental component summary (respectively: coefficient = 0.65, 0.57, 0.78 and 0.90) and four subscales of SF-12 (general health, physical function, bodily pain and physical role) can predict physical component summary (respectively: coefficient = 0.58, 0.70, 0.74 and 0.88). The goodness-of-fit indices showed that the model for predicting mental and physical components in the elderly was excellent (X2 / df = 1.61, RMSEA= 0.07, CFI = 0.96 and NFI=0.92).
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Chesnaye, Nicholas C., Yvette Meuleman, Esther N. M. de Rooij, Ellen K. Hoogeveen, Friedo W. Dekker, Marie Evans, Agneta A. Pagels, et al. "Health-Related Quality-of-Life Trajectories over Time in Older Men and Women with Advanced Chronic Kidney Disease." Clinical Journal of the American Society of Nephrology 17, no. 2 (January 24, 2022): 205–14. http://dx.doi.org/10.2215/cjn.08730621.
Повний текст джерелаАнотація:
Background and objectivesThe effect of sex on longitudinal health-related quality of life remains unknown in CKD. Here we assess differences in the sex-specific evolution of health-related quality of life in older men and women with advanced CKD.Design, setting, participants, & measurementsThe European Quality Study on Treatment in Advanced Chronic Kidney Disease is a European observational prospective cohort study in referred patients with CKD and an incident eGFR<20 ml/min per 1.73 m2 who are ≥65 years of age not on dialysis. Health-related quality of life was measured using the 36-Item Short Form Survey at 3- to 6-month intervals between April 2012 and September 2020, providing Physical Component Summary and Mental Component Summary scores. Trajectories were modeled by sex using linear mixed models, and sex differences in health-related quality-of-life slope were explored.ResultsWe included 5345 health-related quality-of-life measurements in 1421 participants. At baseline, women had considerably lower mean Physical Component Summary (42) and Mental Component Summary (60) compared with men (Physical Component Summary: 55; Mental Component Summary: 69; P<0.001). However, during follow-up, Physical Component Summary and Mental Component Summary scores declined approximately twice as fast in men (Physical Component Summary: 2.5 per year; 95% confidence interval, 1.8 to 3.1; Mental Component Summary: 2.7 per year; 95% confidence interval, 2.0 to 3.4) compared with in women (Physical Component Summary: 1.1 per year; 95% confidence interval, 0.1 to 2.0; Mental Component Summary: 1.6 per year; 95% confidence interval, 0.7 to 2.6). This difference was partly attenuated after adjusting for important covariates, notably eGFR decline. Higher serum phosphate, lower hemoglobin, and the presence of preexisting diabetes were associated with lower Physical Component Summary and Mental Component Summary scores in men but to a lesser extent in women.ConclusionsAmong older men and women with advanced CKD, women had lower health-related quality of life at baseline, but men experienced a more rapid decline in health-related quality of life over time.
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Ghimire, Srijana, and Milan Lopchan. "Quality of life of hemodialysis patients in selected teaching hospitals of Chitwan." Journal of Chitwan Medical College 7, no. 1 (May 24, 2017): 29–34. http://dx.doi.org/10.3126/jcmc.v7i1.17367.
Повний текст джерелаАнотація:
The quality of life (QOL) needs to be regularly assessed in hemodialysis patients. Hemodialysis patients suffer from average quality of life and survival. A descriptive research design was used, 96 respondents who had received haemodialysis treatment after completion of 1 month duration of hemodialysis in two different teaching hospital at Bharatpur, Chitwan. Data was collected by using standard tool Short Form-36 version2 through face to face structure interview schedule. The objective of study is to find out the quality of life (QOL) of haemodialysis patients. Various test such as one sample t-test, ANOVA test, independent t-test, Kruskal-Wallis test and Mann-Whittney U test, Pearson’s correlation was applied. The findings showed that higher proportion of respondents were from 40-59 years (41.0%) and male (62.2%). The mean±SD was 57.45±16.25, 55.72±22.41 and 60.04±11.50 in overall QOL, physical and mental component summary respectively which was slightly above the average. All dimention and sub scale was satistically significant. Younger respondents had statistically significant with overall QOL (p<0.001) and physical component summary (p<0.001). Non diabetics had better in overall QOL (p=0.040) and physical component summary (p=0.033). Level of educational had also positive impact in overall QOL(p=0.010), physical (p=0.006) and mental component summary (p<0.001). Employment status (p=0.020) and sex (p=0.037) was also statistically significant with mental component summary. There was correlation between physical and mental component summary with overall QOL 0.970(p<0.001) and 0.698(p<0.001), and between the physical and mental component summary was 0.502(p<0.001). Below average score were seen in the general health (32.86±25.74) and vitality (41.53±13.98) sub scale. In order to improve quality of life family, physician, nurses and policy makers can use this finding.
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Berget, Anne Mette, Vegard Pihl Moen, Merethe Hustoft, Geir Egil Eide, Jan Sture Skouen, Liv Inger Strand, and Øystein Hetlevik. "Long-Term Change and Predictors of Change in Physical and Mental Function after Rehabilitation: A Multi-Centre Study." Journal of Rehabilitation Medicine 55 (January 5, 2023): jrm00358. http://dx.doi.org/10.2340/jrm.v55.2809.
Повний текст джерелаАнотація:
Objective: To investigate changes and predictors of change in physical and mental function over a 3-year period after rehabilitation.Design: Prospective cohort.Participants: Patients, across diseases, living in western Norway, accepted for somatic specialized interprofessional rehabilitation (n = 984).Methods: Physical and mental function were assessed at admittance (baseline), and after 1 and 3 years using the Medical Outcome Study Short Form 36 (SF-36). Associations between changes in SF-36 component summary scores and sense of coherence, pain, disease group (musculoskeletal, neoplasm, cardiovascular, neurological, other), exercise habits and demographic variables were analysed using linear mixed modelling.Results: In the total group, mean (standard deviation) physical component summary scores improved by 2.9 (8.4) and 3.4 (9.3) points at 1 and 3 years, respectively. Mental component summary scores improved by 2.1 (9.7) and 1.6 (10.8) points. Improvement in physical component summary was significantly greater for patients with higher sense of coherence (b = 0.09, p = 0.001) and for the neoplasm disease group (b = 2.13, p = 0.046). Improvement in mental component summary was significantly greater for patients with low sense of coherence (b = –0.13, p = < 0.001) and higher level of education (b = 3.02, p = 0.0302). Interaction with age (physical component summary: b = 0.22, p = 0.039/mental component summary b = 0.51, p = 0.006) indicated larger effect at 1 year than at 3 years.Conclusion: Physical and mental function improved in the total study group over the 3-year period. Sense of coherence at baseline was associated with improved physical and mental function, suggesting that coping resources are important in rehabilitation. LAY ABSTRACTRehabilitation aims to improve function among people with disabilities. This study investigated how physical and mental function change in a 3-year period after rehabilitation, and the factors related to these changes. In a cohort of 984 rehabilitation patients, physical and mental function were measured before rehabilitation (baseline) and at 1 and 3 years after rehabilitation. Both physical and mental function improved over a period of 3 years, with the greatest improvement from baseline to 1 year. Improved function at 1 year remained relatively stable over time. Participants with higher coping resources at baseline, measured by sense of coherence, had the greatest improvement in physical function, and less improvement in mental function. Participants’ disease group influenced change in physical function. Participants with a higher level of education demonstrated greater improvement in mental function. These results imply that coping resources should be addressed as an important part of rehabilitation.
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Green, Alana J., Neil A. Manson, Melissa D. McKeon, and Edward P. Abraham. "Pain on the Brain: Is the SF-36 Mental Component Summary Enough?" Spine Journal 14, no. 11 (November 2014): S178. http://dx.doi.org/10.1016/j.spinee.2014.08.427.
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Backhaus, Insa, Valeria D’Egidio, Rosella Saulle, Daniele Masala, Alberto Firenze, Elisabetta De Vito, Alice Mannocci, and Giuseppe La Torre. "Health-related quality of life and its associated factors: results of a multi-center cross-sectional study among university students." Journal of Public Health 42, no. 2 (February 26, 2019): 285–93. http://dx.doi.org/10.1093/pubmed/fdz011.
Повний текст джерелаАнотація:
Abstract Background The decline of health among university students represents an important and growing public health concern. Health problems and unhealthy lifestyle habits are common among many students, but factors influencing students’ health are not fully understood. Methods Italian university students from different study programs and curriculum years were asked to fill out a self-administered questionnaire, collecting data about age, gender, curriculum year, study program and health-related quality of life (QOL). Two latent factors were extracted: physical component summary score and mental component summary score. T-test, one-way ANOVA, multivariate and age and sex-stratified analyses were performed. Results Students scored relatively poor on health-related QOL, with an overall mental component summary score of 41,3% (± 10,0) and physical component summary score of 52,9% (±6,0), with significantly higher mental component summary score for male students (P = < 0,005). Studying economics, law (b = −2,513, P = 0,007) or engineering (b = −2,762; P = 0,001) was associated to negatively influence students’ health. Conclusions Factors such as study program are associated with health-related QOL. Further longitudinal studies assessing additional socio-demographic factors are needed to fully assess what influences students’ health. Students’ health should be at the top of the agenda of public health researchers, academic supervisors and policy-makers.
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Ugwueze, Fabian Chibunine, and Olaoluwa Samson Agbaje. "Physical activity domains, levels, and health-related quality of life among Nigerian adolescents during the coronavirus disease 2019 pandemic." SAGE Open Medicine 10 (January 2022): 205031212210888. http://dx.doi.org/10.1177/20503121221088808.
Повний текст джерелаАнотація:
Introduction: The coronavirus disease 2019 pandemic spurred unprecedented public health measures to curb its spread. Such measures might have negatively impacted adolescents’ participation in physical activity and health-related quality of life. However, the evidence is unclear in Nigerian adolescents. This study assessed the physical activity domains, levels, and health-related quality of life in Nigerian adolescents during the coronavirus disease 2019 pandemic. Methods: The sample consisted of 430 students in public secondary schools in Nsukka, Enugu State. The students were randomly selected to participate in the cross-sectional study between November 2020 and April 2021. The Demographic Profile Form, International Physical Activity Questionnaire, Short Form-36 Health Survey, and Perceived Susceptibility to coronavirus disease 2019 Infection Questionnaire were used for data collection. Descriptive statistics, Chi-square test, independent-samples t-test, univariate ANOVA, and multiple linear regressions were conducted using SPSS version 25. Results: The mean score of total physical activity (MET-min/week) was 1651.3 ( SD = 842.18). The mean overall score of health-related quality of life was 78.30 ( SD = 16.43). The mental health component of health-related quality of life showed that adolescents had poor mental health status. Female adolescents had higher mean scores in physical component summary ( M = 83.03; SD = 27.36) and mental component summary ( M = 51.19; SD = 8.69) than the male adolescents, physical component summary ( M = 69.0; SD = 21.65) and mental component summary ( M = 46.15; SD = 10.71). Conclusion: The findings showed a significant positive association among gender, class of study, parental type, perceived susceptibility to coronavirus disease 2019, and physical activity domains, levels, and health-related quality of life. In addition, boys had a higher mean score of total physical activity (MET-min/week) than the girls. More girls were less active than the boys. However, concerning the health-related quality of life, girls had higher mean scores in physical component summary and mental component summary than boys. Physical activity interventions that specifically target female adolescents’ physical activity participation are needed. Also, mental health interventions are needed to improve the mental health status of adolescents, especially boys in the post–coronavirus disease 2019 era.
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Latas, Milan, Tihomir Stojkovic, Tijana Ralic, Svetlana Jovanovic, Zeljko Spiric, and Srdjan Milovanovic. "Medical students` health-related quality of life - a comparative study." Vojnosanitetski pregled 71, no. 8 (2014): 751–56. http://dx.doi.org/10.2298/vsp1408751l.
Повний текст джерелаАнотація:
Background/Aim. Previous studies on medical students? subjective perception of health and health-related quality of life (HRQoL) showed inconclusive results. Moreover, there are no published studies to compare HRQoL of medical students to non-medical university students. The aim of the study was to assess subjective perception of health-related quality of life (HRQoL) in medical students? sample, to compare it with non-medical university stu-dents and to ascertain predictors of better perception of HRQoL in medical students. Methods. Scores of all domains on the Mental and Physical Component Summary subscales and total score of the Short Form Health Survey (SF-36), used for assessment of HRQoL in samples of 561 medical and 332 non-medical university students were assessed and compared. In addition, linear regression to identify predictors of better perception of mental and physical components of HRQoL and overall HRQoL in the sample of medical students was used. The dependant variables were subscores and total score with the SF- 36, and independent variables were certain sociodemographic and academic characteristics of the students. Results. Medical students had statistically significantly higher scores on the Mental Component Summary and total SF-36 score compared to non-medical students. Linear regression analysis demonstrated that higher scores of Physical Component Summary were associated with age, male sex and the year of studies. The Mental Component Summary were associated with age, male sex, the year of studies and marital status. The total SF-36 score was associated with age, male sex and the year of studies. Conclusion. Medical students perceive their health much better than other university students do, but female, older and second grade medical students have worse perception of their HRQoL. Those points should be potential target areas for specific prevention and treatment in order to achieve better HRQoL.
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Sung, Su-Ah, Young Youl Hyun, Kyu Beck Lee, Hayne Cho Park, Wookyung Chung, Yeong Hoon Kim, Yong-Soo Kim, Sue Kyung Park, Kook-Hwan Oh, and Curie Ahn. "Sleep Duration and Health-Related Quality of Life in Predialysis CKD." Clinical Journal of the American Society of Nephrology 13, no. 6 (May 3, 2018): 858–65. http://dx.doi.org/10.2215/cjn.11351017.
Повний текст джерелаАнотація:
Background and objectivesSleep duration has been associated with cardiometabolic risk and mortality. The health-related quality of life represents a patient’s comprehensive perception of health and is accepted as a health outcome. We examined the relationship between sleep duration and health-related quality of life in predialysis CKD.Design, setting, participants, & measurementsIn this cross-sectional study, data from 1910 adults with CKD enrolled in the Korean Cohort Study for Outcome in Patients with CKD were analyzed. Health-related quality of life was assessed with the physical component summary and mental component summary of the Short Form-36 Health Survey. Low health-related quality of life was defined as a Short Form-36 Health Survey score >1 SD below the mean. Using a generalized additive model and multivariable logistic regression analysis, the relationship between self-reported sleep duration and health-related quality of life was examined.ResultsSeven-hour sleepers showed the highest health-related quality of life. We found an inverted U-shaped relationship between sleep duration and health-related quality of life as analyzed by a generalized additive model. In multivariable logistic analysis, short sleepers (≤5 h/d) had lower health-related quality of life (odds ratio, 3.23; 95% confidence interval, 1.86 to 5.60 for the physical component summary; odds ratio, 2.37; 95% confidence interval, 1.43 to 3.94 for the mental component summary), and long sleepers (≥9 h/d) had lower health-related quality of life (odds ratio, 2.80; 95% confidence interval, 1.55 to 5.03 for the physical component summary; odds ratio, 2.08; 95% confidence interval, 1.20 to 3.60 for the mental component summary) compared with 7-hour sleepers. Sleep duration had a significant U-shaped association with low health-related quality of life.ConclusionsThese findings suggest that short or long sleep duration is independently associated with low health-related quality of life in adults with CKD.
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Lizana, Pablo A., and Gustavo Vega-Fernadez. "Teacher Teleworking during the COVID-19 Pandemic: Association between Work Hours, Work–Family Balance and Quality of Life." International Journal of Environmental Research and Public Health 18, no. 14 (July 16, 2021): 7566. http://dx.doi.org/10.3390/ijerph18147566.
Повний текст джерелаАнотація:
Background: Teachers worldwide had to reinvent their work routine according to teleworking during the COVID-19 pandemic, a work format that negatively impacts individuals’ physical and mental health. This study evaluates the association between work hours, work–family balance and quality of life (QoL) among teachers during the Chilean health emergency of the COVID-19 pandemic. Teachers from across Chile were contacted via email and social media to answer an online survey. QoL was evaluated via the SF-36 questionnaire, work hours and work–family balance in the pandemic. A total of 336 teachers from across Chile participated in this study. Teachers had a low QoL score, associated with age (p < 0.05). Teachers who were ≤44 showed lower deterioration risks in the Physical Component Summary (OR: 0.54) than the ≥45-year-old age group; simultaneously, the younger group (≤44 years) had a greater risk (OR: 2.46) of deterioration in the Mental Component Summary than teachers over 45 years. A total of 78.7% of teachers reported having increased their work hours during the COVID-19 pandemic due to teleworking and 86% indicated negative effects on their work–family balance. Pandemic work hours and negative work–family balance increase the risk of reducing the Mental Component Summary (OR: 1.902; OR: 3.996, respectively). Teachers presented low median QoL scores, especially in the Mental Component Summary, suggesting that it would be beneficial to promote a better workload distribution for teachers in emergency contexts, considering the adverse effects of teleworking.
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Jenkinson, Crispin, and Richard Layte. "Development and Testing of the UK SF-12." Journal of Health Services Research & Policy 2, no. 1 (January 1997): 14–18. http://dx.doi.org/10.1177/135581969700200105.
Повний текст джерелаАнотація:
Objectives: The 36 item short form health survey (SF-36) has proved to be of use in a variety of settings where a short generic health measure of patient-assessed outcome is required. This measure can provide an eight dimension profile of health status, and two summary scores assessing physical function and mental well-being. The developers of the SF-36 in America have developed algorithms to yield the two summary component scores in a questionnaire containing only one-third of the original 36 items, the SF-12. This paper documents the construction of the UK SF-12 summary measures from a large-scale dataset from the UK in which the SF-36, together with other questions on health and lifestyles, was sent to randomly selected members of the population. Using these data we attempt here to replicate the findings of the SF-36 developers in the UK setting, and then to assess the use of SF-12 summary scores in a variety of clinical conditions. Methods: Factor analytical methods were used to derive the weights used to construct the physical and mental component scales from the SF-36. Regression methods were used to weight the 12 items recommended by the developers to construct the SF-12 physical and mental component scores. This analysis was undertaken on a large community sample ( n = 9332), and then the results of the SF-36 and SF-12 were compared across diverse patient groups (Parkinson's disease, congestive heart failure, sleep apnoea, benign prostatic hypertrophy). Results: Factor analysis of the SF-36 produced a two factor solution. The factor loadings were used to weight the physical component summary score (PCS-36) and mental component summary score (MCS-36). Results gained from the use of these measures were compared with results gained from the PCS-12 and MCS-12, and were found to be highly correlated (PCS: ρ = 0.94, p < 0.001; MCS: ρ = 0.96, p < 0.001), and produce remarkably similar results, both in the community sample and across a variety of patient groups. Conclusions: The SF-12 is able to produce the two summary scales originally developed from the SF-36 with considerable accuracy and yet with far less respondent burden. Consequently, the SF-12 may be an instrument of choice where a short generic measure providing summary information on physical and mental health status is required. Crispin Jenkinson DPhil, Deputy Director
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Gedam, Manoj, and Dipti Sarma. "Post-surgery Quality of Life in Patients with Acromegaly Using SF36 Quality of Life Questionnaire-prospective Study." Journal of Endocrinology Research 3, no. 2 (August 30, 2021): 34. http://dx.doi.org/10.30564/jer.v3i2.3531.
Повний текст джерелаАнотація:
Introduction: Acromegaly is chronic progressive disease with multisystem involvement characterised by an excess secretion of growth hormone and increased circulating insulin like growth factor 1 concentration.Aims and Objectives: To assess surgical outcome of acromegaly patients at tertiary care institute using SF 36 quality of life questionnaire. SF-36 scores comprise 3 components: the physical component summary (PCS), the mental component summary (MCS) and role-social component summary (RCS).30 acromegaly patients admitted in Guwahati medical college were enrolled in study and followed up post operatively for surgical remission. All participants completed the SF-36 preoperatively, 1 year and 2 years postoperatively.Material and Method: Out of 30 patients 6 patients had surgical remission post operatively on the basis of postoperative glucose suppressed GH Level done after 12 weeks. Preoperatively subscale scores (physical functioning, role physical, general health) which were below the set standards for the normal population show significant postoperative improvements along with mental health (MH) scores. Similarly, PCS, MCS and RCS scores changed significantly after surgery. We also compared the QOL of 6 patients whose peak GH level was < 0.4 µg/L during postoperative oral glucose tolerance testing with those patients whose nadir GH level was ≥ 0.4 µg/L. There was significant difference between partial and complete remission group in subscale score role physical, social function and mental health. Similarly, PCS and RCS score significantly different in partial and complete remission group than MCS score.Conclusions: QOL is considerably reduced in patients with acromegaly compared to general population which improves significantly after surgical treatment. Patients achieving the new remission criteria had significant improvement in physical and social components than those who did not.
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McAllister, David R., Ali R. Motamedi, Sharon L. Hame, Matthew S. Shapiro, and Frederick J. Dorey. "Quality of Life Assessment in Elite Collegiate Athletes." American Journal of Sports Medicine 29, no. 6 (November 2001): 806–10. http://dx.doi.org/10.1177/03635465010290062201.
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The objectives of this study were to establish baseline Medical Outcomes Study Short Form Health Survey (SF-36) data for Division I collegiate athletes and to determine the effects of injury severity and training time. All participating athletes (N = 562) at a major university were evaluated with the SF-36. Regression analysis was performed to identify predictive factors. When the men without injury were compared with a previously established norm group, there was a significant increase in the role emotional score. In the women without injury there were significant increases in mental component summary, physical function, role emotional, mental health, and vitality scores when compared with the norm group. Serious injury was a predictor of lower scores in all domains, whereas minimal injury was predictive of lower physical component summary, role physical, bodily pain, social function, and general health scores. Increased training time was predictive of higher mental component summary, role physical, vitality, and general health scores. Elite collegiate athletes scored differently from previously established age-matched norms, and injury was a strong predictor of lower scores.
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Graetz, A., S. Lai, C. Tang, J. Lua, and G. Thevendran. "SF-36 Mental Component Summary (MCS) doesn’t predict functional outcome after hallux valgus surgery." Foot and Ankle Surgery 22, no. 2 (June 2016): 72–73. http://dx.doi.org/10.1016/j.fas.2016.05.181.
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Raszeja-Wyszomirska, Joanna, Ewa Wunsch, Agnieszka Kempinska-Podhorodecka, Daniel S. Smyk, Dimitrios P. Bogdanos, Malgorzata Milkiewicz, and Piotr Milkiewicz. "TRAF1-C5Affects Quality of Life in Patients with Primary Biliary Cirrhosis." Clinical and Developmental Immunology 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/510547.
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Background. Previous studies reported associations between specific alleles of non-HLA immunoregulatory genes and higher fatigue scores in patients with primary biliary cirrhosis (PBC).Aim. To study the relationship between variables of health-related quality of life (HRQoL) and single nucleotide polymorphisms ofTRAF1-C5, a member of the tumor necrosis factor receptor family.Patients and Methods.TRAF1-C5gene polymorphisms, rs2900180 and rs3761847, were analysed in 120 Caucasian PBCs. The HRQoL was assessed with SF-36, PBC-40, and PBC-27 questionnaires.Results. We found a negative association between TT genotype of rs2900180 and SF-36’s domains vitality (P<0.05), mental health (P<0.05), and mental component summary score (P<0.05). GG homozygotes of rs3761847 had lower vitality (P<0.05), mental health (P<0.05), mental component summary score (P<0.05) and impairment of social functioning (P<0.01). Allelic analysis has shown that T allele of rs2900180 and G allele of rs3761847 related to SF-36’s vitality (P<0.05andP<0.01), social functioning (P<0.05andP<0.05), mental health (P<0.01andP<0.05), and mental component summary score (P<0.01andP<0.05), respectively. Genotyping and allelic analysis did not reveal correlation with PBC-40 and PBC-27 domains.Conclusion. The association between rs2900180 and rs3761847 polymorphisms and HRQoL variables indicates that TRAF1 is involved in the induction of impaired QoL in PBC.
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Wen, Guangju, and Lijun Zheng. "The Influence of Internalized Homophobia on Health-Related Quality of Life and Life Satisfaction Among Gay and Bisexual Men in China." American Journal of Men's Health 13, no. 4 (July 2019): 155798831986477. http://dx.doi.org/10.1177/1557988319864775.
Повний текст джерелаАнотація:
The aim of this study was to examine the influences of internalized homophobia on Chinese gay and bisexual men’s quality of life and life satisfaction. Four hundred and eighty-three participants completed the Internalized Homophobia Scale, Chinese SF-12 Health Survey Version 2, and Satisfaction With Life Scale via the Internet. Scores for quality of life in several domains and life satisfaction were significantly lower than the heterosexuals’ norm scores. The present study revealed that internalized homophobia significantly negatively correlated with the mental component summary score and life satisfaction. The mental component summary score mediated the relationship between internalized homophobia and life satisfaction. Sexual orientation moderated the relationship between internalized homophobia and mental component score. Gay and bisexual men in China experience poorer quality of life and less satisfaction with life compared to heterosexuals, and internalized homophobia contributes to both.
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Nedeljkovic, Una, Nevena Krstic, Slavica Varagic-Markovic, and Svetozar Putnik. "Quality of life and functional capacity one year after coronary artery bypass graft surgery." Acta chirurgica Iugoslavica 58, no. 3 (2011): 81–86. http://dx.doi.org/10.2298/aci1103081n.
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Objectives: To analyze functional capacity and quality of life of patients one year after coronary artery bypass graft surgery (CABG) and identify factors that influence them in order to accomplish maximal recovery. Methods: Observational study included 89 patients undergoing elective CABG, who were tested preoperatively and one year after operation using Short form 12 item health survey (SF-12), Duke Activity Status Index (DASI) questionnaire and questionnaire regarding participation in rehabilitation program. Results: After one year, DASI and quality of life-physical component summary score (SF-12 PCS) significantly improved (p<0.001; p<0.05). No statistically significant improvement in mental component summary has been registered. In domains of physical component summary, only general health was significantly better (p<0.05). There was moderate correlation of SF-12 PCS postoperatively with SF-12 mental component summary (SF-12 MCS) preoperatively. DASI scores preoperatively and postoperatively are found to be significantly higher in men comparing to women (p<0.05). Multiple regression analysis found DASI preoperatively (R2=0.62, ?=0.42, p<0.05) and age (?=-0.53, p<0.05) to be significant predictors of DASI postoperatively in women. Enrollment in rehabilitation program didn?t influence DASI and SF-12 scores one year after CABG. Conclusions: Although functional capacity and physical component of quality of life improved, factors that influence them still remain unclear. It seems that mental health status and personality profile, as well as the alternative modalities of rehabilitation, might play important role in long lasting effects of improvement.
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Hopman, Wilma M., Margaret B. Harrison, Meg Carley, and Elizabeth G. VanDenKerkhof. "Additional Support for Simple Imputation of Missing Quality of Life Data in Nursing Research." ISRN Nursing 2011 (November 16, 2011): 1–4. http://dx.doi.org/10.5402/2011/752320.
Повний текст джерелаАнотація:
Background. Missing data are a significant problem in health-related quality of life (HRQOL) research. We evaluated two imputation approaches: missing data estimation (MDE) and assignment of mean score (AMS). Methods. HRQOL data were collected using the Medical Outcomes Trust SF-12. Missing data were estimated using both approaches, summary statistics were produced for both, and results were compared using intraclass correlations (ICC). Results. Missing data were imputed for 21 participants. Mean values were similar, with ICC >.99 within both the Physical Component Summary and the Mental Component Summary when comparing the two methodologies. When imputed data were added into the full study sample, mean scores were identical regardless of methodology. Conclusion. Results support the use of a practical and simple imputation strategy of replacing missing values with the mean of the sample in cross-sectional studies when less than half of the required items of the SF-12 components are missing.
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Anderson, Sarah, Emily Ridgewell, and Michael Dillon. "The effect of participation in a mobility clinic on self-reported mobility and quality of life in people with lower limb amputation: A pilot study." Prosthetics and Orthotics International 44, no. 4 (June 5, 2020): 202–7. http://dx.doi.org/10.1177/0309364620921749.
Повний текст джерелаАнотація:
Background: Many people with lower limb amputation experience mobility impairment and reduced quality of life. Mobility clinics are designed to improve mobility and quality of life for people with lower limb amputation, but their effectiveness is unknown. Objectives: To compare changes in mobility prior to, and 12 weeks following participation in mobility clinic for people with lower limb amputation, and to explain whether changes in mobility explained changes in quality of life. To determine whether the PLUS-M™ was sensitive to the effects of participation in the mobility clinic, and to estimate the sample size required for a definitive study. Study design: Longitudinal observational. Methods: Electronic versions of the PLUS-M and SF-36v2® were completed by people living in the community with lower limb amputation prior to, and 12 weeks following participation in a mobility clinic. Results: There was a significant increase in mobility from baseline to 12 weeks post participation in the clinic ( p = 0.012). Changes in mobility explained a significant proportion of variance in the SF-36v2 mental component summary ( p = 0.024) but not the physical component summary ( p = 0.804). Conclusion: For people with lower limb amputation, mobility increased after participation in the clinic and this explained improvements in SF-36v2 mental component summary. The PLUS-M was sensitive enough to detect a change in mobility over time. Clinical relevance This preliminary data indicated that participation in a mobility clinic improved mobility and the mental components of quality of life for people living with lower limb amputation. The PLUS-M™ seems sensitive to changes in mobility as a result of participation in a mobility clinic.
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Vieira, Marcelo Carvalho, Fernanda de Souza Nogueira Sardinha Mendes, Paula Simplício da Silva, Gilberto Marcelo Sperandio da Silva, Flavia Mazzoli-Rocha, Andrea Silvestre de Sousa, Roberto Magalhães Saraiva, et al. "The association between variables of cardiopulmonary exercise test and quality of life in patients with chronic Chagas cardiomyopathy (Insights from the PEACH STUDY)." PLOS ONE 17, no. 12 (December 15, 2022): e0279086. http://dx.doi.org/10.1371/journal.pone.0279086.
Повний текст джерелаАнотація:
Studies investigating the association between functional capacity and quality of life (QoL) in individuals with chronic Chagas cardiomyopathy (CCC) usually do not include a gold-standard evaluation of functional capacity, limiting the validity and the interpretation of the results. The present study is a cross-section analysis aiming to evaluate the association between functional capacity (quantified by cardiopulmonary exercise test [CPET]) and QoL in individuals with CCC. QoL was assessed using the SF-36 questionnaire. Sociodemographic, anthropometric, clinical, cardiac function and maximal progressive CPET variables were obtained from PEACH study. Generalized linear models adjusted for age, sex, and left ventricular ejection fraction were performed to evaluate the association between CPET variables and QoL. After adjustments, VO2 peak and VO2 AT were both associated with physical functioning (β = +0.05 and β = +0.05, respectively) and physical component summary (β = +0.03 and β = +0.03, respectively). Double product was associated with physical functioning (β = +0.003), general health perceptions (β = +0.003), physical component summary (β = +0.002), and vitality (β = +0.004). HRR≤12bpm was associated with physical functioning (β = -0.32), role limitations due to physical problems (β = -0.87), bodily pain (β = -0.26), physical component summary (β = -0.21), vitality (β = -0.38), and mental health (β = -0.19). VE/VCO2 slope presented association with all mental scales of SF-36: vitality (β = -0.028), social functioning (β = -0.024), role limitations due to emotional problems (β = -0.06), mental health (β = -0.04), and mental component summary (β = -0.02). The associations between CPET variables and QoL demonstrate the importance of CPET inclusion for a more comprehensive evaluation of individuals with CCC. In this setting, intervention strategies aiming to improve functional capacity may also promote additional benefits on QoL and should be incorporated as a treatment strategy for patients with CCC.
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Modi, Gopesh K., Ashok K. Yadav, Arpita Ghosh, Kajal Kamboj, Prabhjot Kaur, Vivek Kumar, Shobhit Bhansali, et al. "Nonmedical Factors and Health-Related Quality of Life in CKD in India." Clinical Journal of the American Society of Nephrology 15, no. 2 (January 30, 2020): 191–99. http://dx.doi.org/10.2215/cjn.06510619.
Повний текст джерелаАнотація:
Background and objectivesPatient-reported outcomes have gained prominence in the management of chronic noncommunicable diseases. Measurement of health-related quality of life is being increasingly incorporated into medical decision making and health care delivery processes.Design, setting, participants, & measurementsThe Indian Chronic Kidney Disease Study is a prospective cohort of participants with mild to moderate CKD. Baseline health-related quality of life scores, determined by the standardized Kidney Disease Quality of Life 36 item instrument, are presented for the inception cohort (n=2919). Scores are presented on five subscales: mental component summary, physical component summary, burden, effect of kidney disease, and symptom and problems; each is scored 0–100. The associations of socioeconomic and clinical parameters with the five subscale scores and lower quality of life (defined as subscale score <1 SD of the sample mean) were examined. The main socioeconomic factors studied were sex, education, occupation, and income. The key medical factors studied were age, eGFR, diabetes, hypertension, and albuminuria.ResultsThe mean (SD) subscale scores were physical component summary score, 43±9; mental component summary score, 48±10; burden, 61±33; effects, 87±13; and symptoms, 90±20. Among the socioeconomic variables, women, lower education, and lower income were negatively associated with reduced scores across all subscales. For instance, the respective β-coefficients (SD) for association with the physical component summary subscale were −2.6 (−3.4 to −1.8), −1.5 (−2.2 to −0.7), and −1.6 (−2.7 to −0.5). Medical factors had inconsistent or no association with subscale scores. The quality of life scores also displayed regional variations.ConclusionsIn this first of its kind analysis from India, predominantly socioeconomic factors were associated with quality of life scores in patients with CKD.
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Maempel, Julian F., Paul J. Jenkins, and Jane E. McEachan. "The relationship of mental health status to functional outcome and satisfaction after carpal tunnel release." Journal of Hand Surgery (European Volume) 45, no. 2 (August 12, 2019): 147–52. http://dx.doi.org/10.1177/1753193419866400.
Повний текст джерелаАнотація:
We studied whether mental health status is significantly correlated to patient reported functional outcomes and satisfaction after carpal tunnel release. Over a 7-year period, 809 patients completed Short Form-12 (SF-12) questionnaires which allowed calculation of the SF-12 mental component summary 1 year postoperatively, 780 (96%) completed a satisfaction questionnaire and 777 (96%) completed a QuickDisabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. Median QuickDASH score was 55 preoperatively (interquartile range [IQR] 28) and 14 postoperatively (IQR 32). A total of 674 patients were satisfied. Patients with mental disability had worse QuickDASH scores (median 34, IQR 41) and a higher incidence of dissatisfaction (52/245, 21%) than those without mental disability (n = 9, IQR 20, 10%, both p < 0.001). Regression analyses indicated scores in the SF-12 mental component summary were significantly related to postoperative QuickDASH score ( p < 0.001) and satisfaction ( p = 0.02). We concluded that patients with mental disability report poorer outcomes and lower satisfaction rates; however, the majority still exhibit significant improvements and are satisfied. Level of evidence: II
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Christensen, Anne Vinggaard, Jakob Bue Bjorner, Ola Ekholm, Knud Juel, Lars Thrysoee, Britt Borregaard, Trine Bernholdt Rasmussen, Rikke Elmose Mols, Charlotte Brun Thorup, and Selina Kikkenborg Berg. "Increased risk of mortality and readmission associated with lower SF-12 scores in cardiac patients: Results from the national DenHeart study." European Journal of Cardiovascular Nursing 19, no. 4 (November 7, 2019): 330–38. http://dx.doi.org/10.1177/1474515119885480.
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Background: The SF-12v2 health survey (SF-12) is widely used as a generic measure of health-related quality of life. However, interpretation of score differences can be difficult. Aim: To estimate benchmarks for interpretation of score differences on the SF-12 for readmission and all-cause mortality in cardiac patients. Methods: Data from the DenHeart study, a national cross-sectional survey including one year follow-up register data, were used. Patients with ischaemic heart disease, arrhythmia, heart failure and heart valve disease answered the survey at hospital discharge. Cox proportional hazards models were used to regress readmission and all-cause mortality. Results: A total of 10,813 cardiac patients completed the SF-12. For patients with ischaemic heart disease and arrhythmia, a one point lower physical component summary score was associated with a 2% increase in risk in readmission (hazard ratio (HR) 1.022 (95% confidence interval 1.017;1.027) and HR 1.024 (1.018; 1.029), respectively) and a 3% increase in risk for patients with heart failure (HR 1.027 (1.015; 1.038)). A one point lower mental component summary score was associated with a 2% increase in the risk of readmission (HR 1.017 (1.013; 1.022)) across diagnoses. For both the physical and mental component summary score, a one point lower score meant a 5% increase in the risk of all-cause mortality (HR 1.046 (1.031; 1.060) and HR 1.046 (1.029; 1.065), respectively) across diagnoses. Conclusion: In a large group of cardiac patients, a one point lower physical or mental component summary score was associated with an up to 3% increased risk of readmission and a 5% increased risk of mortality in the first year after discharge.
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Li, Yunping, Ranran Wang, Jingqun Tang, Chen Chen, Ling Tan, Zhongshi Wu, Fenglei Yu, and Xiang Wang. "Progressive Muscle Relaxation Improves Anxiety and Depression of Pulmonary Arterial Hypertension Patients." Evidence-Based Complementary and Alternative Medicine 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/792895.
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We explored the effects of progressive muscle relaxation (PMR) on anxiety, depression, and quality of life (QOL) in patients with pulmonary arterial hypertension (PAH). One hundred and thirty Han Chinese patients with PAH were randomly assigned to a PMR group (n=65) and a control group (n=65). In a 12-week study duration, the PMR group received hospital-based group and in-home PMR practice, while the control group received hospital-based mild group stretching and balance exercises. The control group and the PMR group were comparable at baseline. After 12 weeks of intervention, the PMR group showed significant improvement in anxiety, depression, overall QOL, and the mental component summary score of QOL (P<0.05) but not the physical component summary score of QOL or the 6-minute walking distance. In contrast, the control group showed no significant improvement in any of the variables. Moreover, the PMR group showed significant improvement in all QOL mental health domains (P<0.05) but not the physical health domains. In contrast, the control group showed no significant improvement in any QOL domain. In conclusion, this study suggests that PMR practice is effective in improving anxiety, depression, and the mental health components of QOL in patients with PAH.
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Jenkinson, Crispin. "The SF-36 Physical and Mental Health Summary Measures: An Example of How to Interpret Scores." Journal of Health Services Research & Policy 3, no. 2 (April 1998): 92–96. http://dx.doi.org/10.1177/135581969800300206.
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Objectives: To provide normative data, in the form of percentile scores from a community sample, for the Physical Component and Mental Health Component Summary scores derived from the SF-36, and to provide an example of how to interpret scores on these measures, comparing normative results with data from a clinical sample. Method: Normative data were gained from a postal survey using a questionnaire, containing the SF-36 and a number of other items concerned with lifestyles and illness. The questionnaire was sent to 13 042 randomly selected subjects between the ages of 18 and 64 years, drawn from Family Health Services Authority computerised registers for four English counties. The clinical sample comprised 84 patients aged 18–64 years diagnosed with obstructive sleep apnoea (OSA) who were asked to take part in the study. The Physical Component Summary (PCS) score and Mental Health Component Summary (MCS) score gained from the SF-36 health status measure were the outcome measures. Results: The community survey achieved a response rate of 72% (n = 9332). All 84 patients in the age range 18–64 years approached to take part in the OSA study agreed to do so; complete data were available for 60 patients. Results indicated that, prior to treatment, 75% of OSA patients' scores on the PCS/MCS were less than the standardised mean score of 50 and fell in the lowest 34% of scores in the general population. However, after treatment, over 50% of patients scored above the standardised mean score on both the PCS and MCS and more closely mirrored the distribution of the normative sample. Conclusion: The data provided here should enable a more meaningful presentation of data than is generally provided in research papers presenting SF-36 summary scores.
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Papadopoulos, A., I. Vrettos, K. Kamposioras, D. Charitos, G. Giannopoulos, D. Pectasides, D. Niakas, and T. Economopoulos. "Comparing health-related quality of life (HRQL) of cancer patients undergoing chemotherapy with family members in a tertiary hospital." Journal of Clinical Oncology 27, no. 15_suppl (May 20, 2009): e20535-e20535. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.e20535.
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e20535 Background: In Greece there is limited information concerning the HRQL of cancer patients undergoing chemotherapy. The aim of this study was to estimate and compare the HRQL of cancer patients and their relatives during the period of chemotherapy and to investigate potential differences in HRQL. Methods: 122 family members (45 men and 77 women) of mean age 48.3 ±14.5 and 122 cancer patients undergoing chemotherapy (49 men and 73 women) of mean age 56.6 ±15.4 1SD completed the SF-36 health survey by personal interview. The SF-36 health survey was used to evaluate and compare HRQL which contains eight scales measuring physical functioning (PF), role physical (RP), bodily pain (BP), general health perception (GH), vitality (VT), social functioning (SF), role emotional (RE), and mental health (MH), with higher scores (0–100 range) reflecting better-perceived health. Two component summary scores capture the overall physical and mental health (Physical Component Summary or PCS and Mental Component Summary or MCS). Data analysis was performed with SPSS version 13.0 while statistical analysis was performed with Wilcoxon signed ranks test. Results: The table below summarizes the results of our study. Conclusions: Although the physical health was significantly higher in the family members as it was expected for a healthy population, the mental health and especially MCS was significantly lower from the cancer patients undergoing chemotherapy. It seems that medical condition of the patients affects severely the mental HRQL of family members. Supportive psychological programs for both the patients and the family members seem mandatory. [Table: see text] No significant financial relationships to disclose.
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Rohrmoser, Ruy Gil, Albert V. Brasil, Guilherme Gago, Marcelo P. Ferreira, Paulo Valdeci Worm, Jorge L. Kraemer, and Nelson P. Ferreira. "Impact of surgery on pain, disability, and quality of life of patients with degenerative lumbar disease: Brazilian data." Arquivos de Neuro-Psiquiatria 77, no. 8 (August 2019): 536–41. http://dx.doi.org/10.1590/0004-282x20190070.
Повний текст джерелаАнотація:
ABSTRACT Objective: To study the impact of surgery on pain, disability, quality of life, and patient satisfaction in a sample of patients with Degenerative Lumbar Disease (DLD). Methods: Retrospective analysis of prospectively collected data. Comparison between pre and postoperative (6 – 12 months) ODI and SF-36, plus postoperative Patient Satisfaction Index. Results: From a total of 216 patients included, improvement was observed in average scores of pain (201.2%), disability (39.7%), physical quality of life (42%), and mental quality of life (37.8%). Among these patients, 57.7% reached or surpassed the minimal clinically important difference (MCID) for ODI, 57.7% for the SF-36 pain component, 59.7% for the SF-36 physical component summary, and 50.5% achieved or surpassed the MCID for the SF-36 mental component summary. Conclusions: Surgery produced a significantly positive impact on pain, disability, and quality of life of patients. Overall, 82.5% of the patients were satisfied.
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Sugawara, Norio, Ken Sato, Ippei Takahashi, Ryu Satake, Shinsaku Fukuda, Shigeyuki Nakaji, and Norio Yasui-Furukori. "Irritable bowel syndrome and quality of life in a community-dwelling population in Japan." International Journal of Psychiatry in Medicine 53, no. 3 (December 27, 2017): 159–70. http://dx.doi.org/10.1177/0091217417749791.
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Objective Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders and is characterized by recurrent abdominal pain or abnormal defecation. This investigation evaluated the relationship between IBS and self-reported quality of life in a community-dwelling population in Japan. Methods For this cross-sectional survey, we enrolled 1002 volunteers who participated in the Iwaki Health Promotion Project in 2013. IBS symptoms were evaluated using the criteria from the Japanese version of the Rome III Questionnaire. The assessments included an interview to obtain sociodemographic data, the second version of the Short-Form Health Survey (SF-36), and the Center for Epidemiologic Studies Depression Scale. Multiple regression analysis was used to assess the relationship between IBS symptoms and scores on the SF-36. Results A total of 59 subjects (5.9%) were classified as having IBS. Scores for all eight domains of the SF-36, the physical component summary, and the mental component summary were significantly and negatively associated with the Center for Epidemiologic Studies Depression scores. Physical functioning, role physical, vitality, mental health, and physical component summary scores were significantly and negatively associated with IBS. Conclusions The burden of IBS symptoms affects both physical and mental wellbeing, even after adjusting for confounders. Our findings suggest that screening for IBS symptoms and evaluating the need for medical care is important for community health workers.
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Bolge, S. C., N. M. Flores, and J. Phan. "Utilizing the sf-36v2 mental Component Summary Score to describe Mental well-Being Experienced By Patients with Type 2 Diabetes." Value in Health 18, no. 3 (May 2015): A67. http://dx.doi.org/10.1016/j.jval.2015.03.389.
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Gülbahar, Selmin, Hüseyin Aydoğmuş, Merve Velioğlu, Ebru Şahin, Hasan Tatari, Halit Pınar, and Elif Akalın. "The Association Between Knee Pain, Symptoms, Function and Quality af Life After Anterior Cruciate Ligament Reconstruction at Short-Term Follow-Up." Orthopaedic Journal of Sports Medicine 2, no. 11_suppl3 (November 1, 2014): 2325967114S0018. http://dx.doi.org/10.1177/2325967114s00182.
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Objectives: To investigate the associations between pain, symptoms, function and knee-related quality of life (QOL) after ACL reconstruction at short-term follow-up Methods: Twenty patients who had undergone ACL reconstruction were included in the study. Knee Injury and Osteoarthritis Outcome Score-Turkish (KOOS-T) was used to evaluate knee pain, other symptoms (symptoms), activities of daily living and sport and recreation (Sport/Rec). Quality of life was assessed with Short Form (SF)-36. Lysholm knee scoring scale was used for clinical evaluation. Results: The mean age of patients was 28. 2 ± 5.5 and the mean time passed after surgery was 38.22 ± 24.7 weeks. A significant correlation (p<0, 05) was found between KOOS-T pain, activities of daily living subscales and all SF-36 subscale scores and both physical component and mental component summary scores. KOOS symptoms and Sports/Rec subscales were correlated with physical and social functioning subscale scores and mental component summary scores of SF-36. Symptoms subscale was also correlated with vitality subscale of SF-36. There was no correlation between SF-36 scores and age and time passed after surgery. Lysholm score was also correlated with most of the subscales of SF-36 but especially with physical component summary score. Conclusion: The QOL of patients who had undergone ACL reconstruction was significantly correlated with pain and activities of daily living. The mental health subscales of SF-36 also correlated with pain, symptoms, ADL and Sports/Rec suggesting that apart from the physical impairment, mental health is also an important clinical issue in patients who had undergone ACL reconstruction.
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ROSA-E-SILVA, Lucilene, Rose Meire Albuquerque PONTES, Grazieli Lopes Matta e. VENDRAME, Felipe Augusto Linhares XAVIER, Gabriel Afonso Dutra KRELING, and Philipe Quagliato BELLINATI. "IMPAIRED QUALITY OF LIFE IN CHAGAS ACALASIA PATIENTS AND ASSOCIATED CLINICAL FACTORS." Arquivos de Gastroenterologia 59, no. 2 (June 2022): 281–87. http://dx.doi.org/10.1590/s0004-2803.202202000-50.
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ABSTRACT Background: No study has focused on Health-Related Quality of Life (HRQoL) for Chagas Achalasia patients. Objective: To compare HRQoL between Chagas Achalasia patients and the general population; and to correlate HRQoL with clinical factors that can affect it. Methods: Sixty Chagas Achalasia patients and 50 controls were evaluated. All patients underwent esophageal manometry for the diagnosis of achalasia and esophagogram to determine the grade of megaesophagus. Three questionnaires were used: 1) clinical: the following data were collected: demographic, medical history, body mass index, occurrence of six esophageal symptoms (Esophageal Symptom Score: number of symptoms reported by patients), duration of dysphagia; 2) socio-economic-cultural status evaluation: patients and controls answered seven questions about their socio-economic-cultural conditions; 3) HRQoL: the validated Brazilian-Portuguese version of the Short-form Health Survey (SF-36) questionnaire (license QM020039) was used. It measures health in eight domains: 3a) four physical: physical functioning, role limitations relating to physical health, bodily pain, and general health perception; 3b) four mental: vitality, social functioning, role limitations relating to emotional health, and mental health. These domains can be summarized into Physical and Mental Summary scores. We analyzed correlations between SF-36 Physical/Mental Summary Component scores and the following clinical factors: Esophageal Symptom Score, duration of dysphagia, body mass index, grades of megaesophagus (defined by the esophagogram) and presence/absence of megacolon (defined by opaque enema). Results: Patients and controls had similar age, gender, medical history, and socio-economic-cultural lifestyles (P>0.05). All patients had dysphagia and megaesophagus. SF-36 scores were significantly lower in Chagas Achalasia patients than controls for all eight domains (physicals: P<0.002; mentals: P<0.0027). The Physical and Mental Summary Component scores were also lower in Chagas Achalasia patients than controls (P<0.0062). For patients, the Physical Summary score was negatively correlated to Esophageal Symptom Score (P=0.0011) and positively correlated to body mass index (P=0.02). No other correlations were found. Conclusion: Chagas Achalasia patients have an impaired HRQoL in all physical and mental domains. Patients reporting more symptoms had worse physical domains. Patients with higher body mass index had better physical domains.
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Petrov, V. S. "Quality of life in patients with chronic rheumatic heart disease." Medical Council, no. 16 (September 27, 2018): 130–34. http://dx.doi.org/10.21518/2079-701x-2018-16-130-134.
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The article presents the results of a study of the quality of life in 102 non-surgically treated patients with chronic rheumatic heart disease (CRHD) over 5 years. The authors used questionnaires to assess the quality of life: the Short Form Medical Outcomes Study (SF-36), the Kansas City Cardiomyopathy Questionnaire (KCCQ) and the Minnesota Living with Heart Failure Questionnaire (MHFLQ). During 5-year follow-up, a statistically significant decrease in the total index of SF-36 physical health component from 36.39 ± 0.54 to 34.04 ± 0.74 and the functional status KCCQ from 23.14 ± 0.56 to 21.2 ± 0.58 was recorded against a 18.6 meters decrease in 6 minute walk distance, an increase in dyspnoea according to a visual analogue scale, a 0.1 cm2 decrease in the mitral orifice area and an increase in the atrium size. According to the summary of the SF-36 mental health component, the total clinical KCCQ indicator, and according to MHFLQ data, no statistically significant changes were observed. Two summary indicators of the KCCQ questionnaire had a significant correlation with SF-36: the functional KCCQ status correlated with the physical (correlation coefficient 0.689) and SF-36 mental (correlation coefficient 0.365) health components. The overall clinical KCCQ indicator also correlated with the SF-36 physical (correlation coefficient 0.305) and mental health – 38.65 ± 0.73 (correlation coefficient 0.588) components. Thus, SF-36 and KCCQ proved to be the most appropriate questionnaires to assess the quality of life of patients with CRDS.
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Lin, Yi-Hsuan, Hsiao-Ting Chang, Yen-Han Tseng, Harn-Shen Chen, Shu-Chiung Chiang, Tzeng-Ji Chen, and Shinn-Jang Hwang. "Do Metabolically Healthy People with Obesity Have a Lower Health-Related Quality of Life? A Prospective Cohort Study in Taiwan." Journal of Clinical Medicine 10, no. 21 (October 30, 2021): 5117. http://dx.doi.org/10.3390/jcm10215117.
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The association between metabolically healthy obesity (MHO) and health-related quality of life (HRQOL) has not been thoroughly evaluated. This study enrolled 906 adult participants aged 35–55 years between 2009 and 2010 in Northern Taiwan; 427 participants were followed up after eight years. Normal weight, overweight, and obesity were evaluated via body mass index. Metabolic health was defined as the absence of cardiometabolic diseases and having ≤1 metabolic risk factor. HRQOL was evaluated using the 36-Item Short Form Health Survey (SF-36), Taiwan version. Generalized linear mixed-effects models were used to analyze the repeated, measured data with adjustment for important covariates. Compared with metabolically healthy normal weight individuals, participants with metabolically unhealthy normal weight and obesity had a significantly poorer physical component summary score (β (95% CI) = −2.17 (−3.38–−0.97) and −2.29 (−3.70–−0.87), respectively). There were no significant differences in physical and mental component summary scores among participants with metabolically healthy normal weight, overweight, and obesity. This study showed that metabolically healthy individuals with obesity and normal weight had similar HRQOL in physical and mental component summary scores. Maintaining metabolic health is an ongoing goal for people with obesity.
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Jolly, M., N. Annapureddy, L. Arnaud, and H. Devilliers. "Changes in quality of life in relation to disease activity in systemic lupus erythematosus: post-hoc analysis of the BLISS-52 Trial." Lupus 28, no. 14 (November 1, 2019): 1628–39. http://dx.doi.org/10.1177/0961203319886065.
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Objectives To quantify changes in generic patient-reported outcomes against clinically meaningful, disease activity measures in systemic lupus erythematosus (SLE). Methods Using BLISS-52 trial data (867 SLE patients), we estimated the mean difference in change of patient-reported outcome scores (Medical Outcomes Study SF-36 and FACIT-fatigue) in relation to disease activity (SELENA-SLEDAI, SELENA-SLEDAI flare index, SLE responder index and British Isles Lupus Assessment Group (BILAG)), considering all study visits by the mean of multivariate mixed models. Predefined disease activity criteria were used to define for improvement and worsening. Results Mean changes in physical component summary/mental component summary and FACIT-fatigue in response to changes in SELENA-SLEDAI and SELENA-SLEDAI flare index were significantly lower than 2.5. New SELENA-SLEDAI flare index flare led to a significant change in all patient-reported outcome scores, except role emotional. Mean improvement in patient-reported outcomes with achievement of SLE responder index ranged between +6.2 (physical function) and +11.3 (bodily pain) for SF-36 domains, + 3.4 and +3.3 for mental component summary and physical component summary, and was +4.2 for FACIT-fatigue. When considering disease activity changes by organ system, changes in BILAG (constitutional) was independently associated with significant changes in FACIT-fatigue and all SF-36 domains (except physical function), changes in BILAG (musculoskeletal and hematological) were independently associated with significant changes in patient-reported outcome scores, except for role emotional (musculoskeletal) and general health/mental health (hematological). Mean changes in every SF-36 domain varied (and was >5) with SLE responder index attainment. Conclusions Knowledge of changes in patient-reported outcomes, against clinically meaningful changes in SLE disease activity measures, is crucial for designing of clinical trials, interpretation of results and shared decision-making for patient care.
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Fleischhacker, W. Wolfgang, Jonathan Rabinowitz, Georg Kemmler, Mariëlle Eerdekens, and Angelika Mehnert. "Perceived functioning, well-being and psychiatric symptoms in patients with stable schizophrenia treated with long-acting risperidone for 1 year." British Journal of Psychiatry 187, no. 2 (August 2005): 131–36. http://dx.doi.org/10.1192/bjp.187.2.131.
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BackgroundThe extent to which antipsychotics improve patients' well-being is uncertain.AimsTo examine psychopathology and patient-rated functioning and well-being in patients treated with risperidone.MethodIn a 1-year, open-label, international multicentre trial of long-acting risperidone in 615 stable adult patients with schizophrenia, self-rated functioning and well-being were measured every 3 months using the Short Form 36-item questionnaire (SF–36). Psychopathology was quantified using the Positive and Negative Syndrome Scale (PANSS).ResultsSignificant improvements were found on the SF–36 mental component summary score and vitality and social functioning scales. PANSS and mental component summary scores were moderately correlated.ConclusionsPatient-reported functioning and well-being appear to differ from investigator-rated psychotic symptoms. Patient-rated well-being should be assessed with symptoms to help measure treatment outcomes.
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Shreve, Gregory M. "Integration of translation and summarization processes in summary translation." Translation and Interpreting Studies 1, no. 1 (January 1, 2006): 87–109. http://dx.doi.org/10.1075/tis.1.1.06shr.
Повний текст джерелаАнотація:
"Summary translation" is a form of translation that is much more common in the federal government than in commercial environments, and so is rarely studied and generally ill understood. While it involves many of the processes that emerge in the nor-mal full translation task (verbatim translation in government parlance), because the final result of this cross-language task is a summary as well as a translation, the summary translator must effectively integrate the component cognitive processes of both summari-zation and translation. The extreme transactional influence of the request for information that initiates a summary translation produces at least four significant areas of difference between summary and full translation, which involve: the extent of semantic reduction and linguistic compression/expansion, the extent of source-text/target text correspondence, and the differential weighting of semantic content. Each of these areas of difference has implications for some of the gross cognitive processes underlying translation: text com-prehension (from reading or listening), hierarchical discourse processing, mental model construction, task-based decision-making/problem-solving, and text production.
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Goda, Akio, Shin Murata, Hideki Nakano, Kayoko Shiraiwa, Teppei Abiko, Koji Nonaka, Hiroaki Iwase, Kunihiko Anami, and Jun Horie. "Subjective and Objective Mental and Physical Functions Affect Subjective Cognitive Decline in Community-Dwelling Elderly Japanese People." Healthcare 8, no. 3 (September 18, 2020): 347. http://dx.doi.org/10.3390/healthcare8030347.
Повний текст джерелаАнотація:
Subjective cognitive decline (SCD) is complex and not well understood, especially among Japanese people. In the present study, we aimed to elucidate the relationships of subjective and objective mental and physical function with SCD among older community-dwelling Japanese adults. SCD was evaluated using the Kihon Checklist: Cognitive Function. Other parameters were evaluated using the Mini-Mental State Examination (MMSE) and the five-item version of the Geriatric Depression Scale (GDS-5), for an objective mental function other than SCD. A timed up-and-go test (TUG) and knee extension strength were used to test objective physical function, and the Mental Component Summary (MCS) and Physical Component Summary (PCS) in the Health-Related Quality of Life survey eight-item short form (SF-8) were used for subjective mental and physical functions. The results of the MMSE, GDS-5, TUG, knee extension strength, and MCS were significantly worse in the SCD group. In addition, logistic regression analysis showed that GDS-5 and MCS were associated with SCD onset. Depressive symptoms and decreased subjective mental function contribute to SCD among community-dwelling Japanese adults. These findings will be useful for planning dementia prevention and intervention programs for older Japanese adults.
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Romero-Gómez, Benjamín, Paula Guerrero-Alonso, Juan Manuel Carmona-Torres, Diana P. Pozuelo-Carrascosa, José Alberto Laredo-Aguilera, and Ana Isabel Cobo-Cuenca. "Health-Related Quality of Life in Levothyroxine-Treated Hypothyroid Women and Women without Hypothyroidism: A Case–Control Study." Journal of Clinical Medicine 9, no. 12 (November 27, 2020): 3864. http://dx.doi.org/10.3390/jcm9123864.
Повний текст джерелаАнотація:
The use of levothyroxine is not always related to the elimination of the symptoms of hypothyroidism. The aim of this study is to compare the health-related quality of life (HRQOL) of a group of hypothyroid women under levothyroxine treatment with that of a group of non-hypothyroid women. Methodology: A case–control study was performed. We used convenience sampling. The case group consisted of 152 levothyroxine-treated hypothyroid women; the control group consisted of 238 women without hypothyroidism disorders. All of the participants were euthyroid according to the clinical practice guidelines. We used as instruments the Short Form-12 questionnaire (SF-12v1) and a sociodemographic questionnaire. Results: Hypothyroid women scored significantly lower in HRQOL in SF-12v1 mental and physical components than the control group (mental component summary: 41.23 ± 12.12 vs. 46.45 ± 10.22, p < 0.001; physical component summary: 49.64 ± 10.16 vs. 54.75 ± 5.76, p < 0.001). body mass index (BMI) and age showed an influence on the physical component (p < 0.001 in both variables). Adjusted for age and BMI, hypothyroidism was still related to worse scores (p < 0.001). Conclusion: Despite being euthyroid, women with hypothyroidism showed a poorer quality of life than women without hypothyroidism. Health professionals need to assess the HRQOL of women with hypothyroidism. Further research on HRQOL and hypothyroidism is needed.
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You, Jungwan, Soeun Lee, Heejae Kim, Yoojin Shim, Aram Kim, Chulsoon Choi, and Taeyong Han. "Effect of Aerobic Capacity on Health-Related Quality of Life in Adults with Cerebral Palsy." Journal of Medical Imaging and Health Informatics 10, no. 6 (June 1, 2020): 1408–12. http://dx.doi.org/10.1166/jmihi.2020.3062.
Повний текст джерелаАнотація:
This study aimed to investigate the relationship between aerobic capacity and health-related quality of life (HRQOL) in men with cerebral palsy (CP) by measuring aerobic capacity and using the Health-Related Quality of Life questionnaire. The subjects were ambulant men with CP (N = 34), with a mean age, height, weight, and body mass index of 36.6 ± 9.2 years, 163.9 ± 8.9 cm, 58.6 ± 9.1 kg, and 21.6 ± 2.9 kg·m-2, respectively. Aerobic capacity was measured during a graded exercise test and shuttle run test. Quality of life was evaluated using the Health-Related Quality of Life (Medical Outcomes Study Short Form-36 [SF-36]). The analysis performed using the physical scale of HRQOL as the dependent variable revealed that the contribution rate of physical functioning was 46.3%, role physical was 21.8%, bodily pain was 7.5%, general health was 27.3%, and physical component summary was 36.1%; the aerobic capacity differed significantly in terms of physical functioning, role physical, general health, and physical component summary (p < .05). Peak oxygen uptake was a particularly significant explanatory variable for role physical, and role physical (p < .05). However, the analysis performed using the mental scale of HRQOL as the dependent variable revealed that the contribution rate of vitality was 13.0%, social functioning was 17.3%, role emotional was 14.9%, mental health was 8.1%, and mental component summary was 15.3%; the aerobic capacity showed no significant difference. The aerobic capacity representing the athletic performance level of men with CP positively affected physical health satisfaction but not mental health satisfaction.
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Bhuiyan, Dr Mohammad Kamruzzaman, Prof Abul Khair Mohammad Salek, Dr Fahmida Sultana, Dr Moshiur Rahman Khasru, Prof Md Moniruzzaman Khan, Prof Md Ali Emran, Dr Farzana Khan Shoma, Dr Mohammad Farid Raihan, and Prof Dr Mohammad Hossain. "The Co-Relation between Disease Activity and Quality of Life among Patients with Peripheral Spondyloarthropathy." Saudi Journal of Medicine 7, no. 8 (August 30, 2022): 455–62. http://dx.doi.org/10.36348/sjm.2022.v07i08.010.
Повний текст джерелаАнотація:
Background: More disability and incapacity to work and a poorer quality of life in spondyloarthritis (SpA) in the presence of enthesitis is associated with higher disease activity. Objective: To find out the co-relation between disease activity and quality of life among patients with peripheral spondyloarthropathy. Methodology: From March 2021 to February 2022, the Department of Physical Medicine and Rehabilitation at BSMMU, Dhaka, performed a cross-sectional research. A total of 105 individuals diagnosed with pSpA who were included in the trial were chosen on purpose. Excluded from the research were patients with concomitant systemic inflammatory rheumatic diseases such as RA, SSc, lupus, and Dermatomyositis. The validated Bengali version of The Ankylosing Spondylitis Disease Activity Score (ASDAS), including C-reactive protein (ASDAS-CRP), was used to measure disease activity, while the validated Bengali version of the Short Form Health Survey (SF) 12v2 was used to evaluate health-related quality of life. Results: The participants' mean age was 38.8(±9.8) years, and 68(64.8%) were male. The mean duration of sickness was 4.3(±3.3) years, with 55.4% of cases lasting less than 3 years. The mean ASDAS-CRP was 3.9(±0.08), with 69(65.7%) individuals having a very high Disease Activity Score. 100% of the individuals in the research experienced arthritis and inflammatory back pain. The majority of research subjects had the HLA B27 gene (N=101, or 96.2%), and 99(94.3%) had enthesitis. Physical Component Summary (PCS) and Mental Component Summary (MCS) mean scores were 34(±7.8) and 41(±7.7), respectively. A slight negative association existed between age and PCS scores on the SF-12 (r=-0.233, p=0.017). There was a negative connection between illness duration and PCS (r=-0.339, p=0.001) and MCS (r=-0.290, p=0.003) SF-12 scores. Again, there was a moderate negative connection between ASDAS-CRP and the PCS and MCS scores of the SF-12 (r=-0.406, p=0.001) and the MCS scores of the SF-12 (r=-0.461, p0.001). Conclusion: The Disease Activity Score of the majority of individuals with peripheral spondyloarthritis was very high. The psychological health of these patients was superior to their physical health. Both physical and mental health components were negatively linked with illness duration. There was a moderate inverse connection between ASDAS-CRP and the Physical Component Summary (PCS) and Mental Component Summary (MCS) scores of the SF-12.
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Diaz, Roberto Jose, Nicole Maggacis, Shudong Zhang, and Michael D. Cusimano. "Determinants of quality of life in patients with skull base chordoma." Journal of Neurosurgery 120, no. 2 (February 2014): 528–37. http://dx.doi.org/10.3171/2013.9.jns13671.
Повний текст джерелаАнотація:
Object Skull base chordomas can be managed by surgical intervention and adjuvant radiotherapy. As survival for this disease increases, identification of determinants of quality of life becomes an important focus for guiding comprehensive patient care. In this study the authors sought to measure functional outcome and quality of life in patients with skull base chordomas and to identify determinants of quality of life in these patients. Methods The authors carried out an internet-based cross-sectional survey, collecting detailed data for 83 individual patients. Demographic and clinical variables were evaluated. Functional outcomes were determined by Karnofsky Performance Scale (KPS) and Glasgow Outcome Scale Extended (GOSE), quality of life was measured using the 36-Item Short Form Health Survey (SF-36), and depression was assessed using Patient Health Questions–9 (PHQ-9) instrument. Caregiver burden was assessed using the Zarit Burden Interview (ZBI). Univariate and multivariate analysis was performed to identify determinants of the physical and mental components of the SF-36. Results Patients with skull base chordomas who have undergone surgery and/or radiation treatment had a median KPS score of 90 (range 10–100, IQR 10) and a median GOSE score of 8 (range 2–8, IQR 3). The mean SF-36 Physical Component Summary score (± SD) was 43.6 ± 11.8, the mean Mental Component Summary score was 44.2 ±12.6, and both were significantly lower than norms for the general US population (p < 0.001). The median PHQ-9 score was 5 (range 0–27, IQR 8). A PHQ-9 score of 10 or greater, indicating moderate to severe depression, was observed in 29% of patients. The median ZBI score was 12 (range 0–27, IQR 11), indicating a low burden. Neurological deficit, use of pain medication, and requirement for corticosteroids were found to be associated with worse SF-36 Physical Component Summary score, while higher levels of depression (higher PHQ-9 score) correlated with worse SF-36 Mental Component Summary score. Conclusions Patients with skull base chordomas have a lower quality of life than the general US population. The most significant determinants of quality of life in the posttreatment phase in this patient population were neurological deficits (sensory deficit and bowel/bladder dysfunction), pain medication use, corticosteroid use, and levels of depression as scored by PHQ-9.
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Simon, Janet E., and Carrie L. Docherty. "Current Health-Related Quality of Life in Former National Collegiate Athletic Association Division I Collision Athletes Compared With Contact and Limited-Contact Athletes." Journal of Athletic Training 51, no. 3 (March 1, 2016): 205–12. http://dx.doi.org/10.4085/1062-6050-51.4.05.
Повний текст джерелаАнотація:
Previous researchers have shown that current health-related quality of life (HRQoL) is lower in former National Collegiate Athletic Association Division I athletes than in nonathletes. However, evidence supports the idea that individuals in collision sports (football) may suffer more serious injuries that may affect them later in life.Context: To measure HRQoL in former Division I collision, contact, and limited-contact athletes.Objective: Cross-sectional study.Design: Research laboratory.Setting: A total of 374 former Division I athletes between the ages of 40 and 65 years were separated into collision, contact, and limited-contact groups.Patients or Other Participants: All individuals completed the Short Form 36 version 2 via a computer.Intervention(s): The dependent variables were the physical component and mental component summary scores and the physical functioning, physical role functioning, bodily pain, general health, vitality, social role functioning, emotional role functioning, and mental health scales. An initial multivariate analysis of covariance included data from the 2 domains: physical component and mental component summary scores. The second multivariate analysis of covariance included data from the 8 dimensions: physical function, role physical, bodily pain scale, general health, mental health, role emotional, social function, and vitality scales. The α level was set at P < .05 with a covariate of sex.Main Outcome Measures(s): The responses were significantly lower (worse) for the former collision athletes compared with the contact and limited-contact athletes for the summary scores (F2,370 = 90.09, P < .01) and all 8 scales (F8,364 = 24.33, P < .01). The largest differences were between the collision and limited-contact athletes for the bodily pain and role physical scales, with mean differences of 12.91 and 11.80 points, respectively.Results: Competing at the Division I level can be strenuous on an athlete's physical, mental, and social dimensions, which can affect the athlete later in life. Based on these data, collision athletes may sacrifice their future HRQoL compared with contact and limited-contact athletes.Conclusions:
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Hopman, W. M., M. B. Harrison, H. Coo, E. Friedberg, M. Buchanan, and E. G. VanDenKerkhof. "Associations between chronic disease, age and physical and mental health status." Chronic Diseases in Canada 29, no. 3 (May 2009): 108–17. http://dx.doi.org/10.24095/hpcdp.29.3.03.
Повний текст джерелаАнотація:
This paper examines the associations between chronic disease, age, and physical and mental health-related quality of life (HRQOL), using data collected in 10 studies representing five chronic conditions. HRQOL was measured using the SF-36 or the shorter subset, SF-12. Physical Component Summary (PCS) and Mental Component Summary (MCS) scores were graphed by condition in age increments of 10 years, and compared to age- and sex-adjusted normative data. Linear regression models for the PCS and MCS were controlled for available confounders. The sample size of 2418 participants included 129 with renal failure, 366 with osteoarthritis (OA), 487 with heart failure, 1160 with chronic wound (leg ulcer) and 276 with multiple sclerosis (MS). For the PCS, there were large differences between the normative data and the mean scores of those with chronic diseases, but small differences for the MCS. Female gender and comorbid conditions were associated with poorer HRQOL; increased age was associated with poorer PCS and better MCS. This study provided additional evidence that, while physical function could be severely and negatively affected by both chronic disease and advanced age, mental health remained relatively high and stable.
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Quigley, Matthew, Michael P. Dillon, and Emily J. Duke. "Comparison of quality of life in people with partial foot and transtibial amputation: A pilot study." Prosthetics and Orthotics International 40, no. 4 (February 25, 2015): 467–74. http://dx.doi.org/10.1177/0309364614568414.
Повний текст джерелаАнотація:
Background:Quality of life is often cited as a key influence in decisions about partial foot and transtibial amputations despite there being no studies comparing quality of life in these groups.Objectives:To compare quality of life in people with partial foot amputation or transtibial amputation secondary to peripheral vascular disease and determine factors influencing quality of life in these cohorts.Study design:Cross-sectional.Methods:Mail-out, mail-back version of the SF-36v2 Health Survey and an adapted version of the demographic section of the Trinity Amputation and Prosthesis Experience Scales–Revised were sent to people recruited through a large metropolitan hospital.Results:Both the SF-36v2 mental health component summary and physical component summary scores were comparable in the partial foot amputation (n = 10) and transtibial amputation (n = 23) cohorts. A multivariate linear regression showed that age, time with diabetes and the presence of retinopathy significantly influenced either the SF-36v2 mental health component summary or physical component summary whereas amputation level did not.Discussion:Results support existing descriptive data that indicate quality of life is comparable in cohorts with partial foot and transtibial amputation.Conclusion:Our results suggest that quality of life need not to be a consideration when deciding between partial foot and transtibial amputation for persons with vascular disease. Surgeons and patients may wish to focus on other considerations, such as the relative risk of ulceration and subsequent amputation, when choosing between partial foot and transtibial amputation.Clinical relevanceThe similarity in quality of life between people with partial foot and transtibial amputation helps inform difficult decisions about amputation surgery by focusing on surgery that will reduce the risk of complications and secondary amputation without fear of compromising quality of life.
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George Albert, Wanda Kiyah, and Adi Fahrudin. "Quality of LiFe (QOL) Assessment Among Advance Cancer Patient Undergoing Palliative Treatment in Malaysia." Asian Social Work Journal 2, no. 2 (December 15, 2017): 26–35. http://dx.doi.org/10.47405/aswj.v2i2.18.
Повний текст джерелаАнотація:
The community's stigma towards advanced cancer patients at the final stages of cancer ending up with this death, has deny their need and right to receive the best service and treatment at the end of their lives. Although there was abundant research on cancer patient issues, but there was still lack of research that focusing on final stage of cancer patients in Malaysia. This cross-sectional study is done to gives overall picture of quality of life (QOL) among final stage of cancer patient and to identify the factor that differentiate the score of QOL for the final stage of cancer patients that receiving palliative treatment at the one medical centres in Kuala Lumpur. The cross-sectional study that has been done with 120 of cancer patients that receiving palliative treatment using convenience sampling. The SF-36 questionnaire has been used to measures Quality of Life (QOL) across eight domains based on physically and emotionally component summary. Results showed that the highest score of QOL were observed in the Mental Component Summary (44.93±6.84) compared with Physical Component Summary at (42.24± 7.91). There is a difference in QOL based on mental and physical component especially from patient social demography. Mental component score have difference in term of age (t = - 0.38; p <0.001), type of cancer (F = 5.522: p <0.001), duration of treatment (t = 5.15; p < 0.001), type of treatment (F = 3.11; p = 0.029) and amount of financial support (F = 7.16; p <0.001). Meanwhile, score for physical component composite has shown difference of score based on level of education (F = 6.21; p <0.001), type of cancer (F = 5.96; p <0.001) and also amount of financial support (F = 3.00; p = 0.033). Further study should be conducted in social work perspective to identify other factors that contribute to the patient QoL and identify problems that prevent them from getting social service, so that the service given by social worker can be improved.
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Lemieux, Julie, Michael D. Brundage, Wendy R. Parulekar, Paul E. Goss, James N. Ingle, Kathleen I. Pritchard, Paul Celano, et al. "Quality of Life From Canadian Cancer Trials Group MA.17R: A Randomized Trial of Extending Adjuvant Letrozole to 10 Years." Journal of Clinical Oncology 36, no. 6 (February 20, 2018): 563–71. http://dx.doi.org/10.1200/jco.2017.75.7500.
Повний текст джерелаАнотація:
Purpose MA.17R was a Canadian Cancer Trials Group–led phase III randomized controlled trial comparing letrozole to placebo after 5 years of aromatase inhibitor as adjuvant therapy for hormone receptor–positive breast cancer. Quality of life (QOL) was a secondary outcome measure of the study, and here, we report the results of these analyses. Methods QOL was measured using the Short Form-36 (SF-36; two summary scores and eight domains) and menopause-specific QOL (MENQOL; four symptom domains) at baseline and every 12 months up to 60 months. QOL assessment was mandatory for Canadian Cancer Trials Group centers but optional for centers in other groups. Mean change scores from baseline were calculated. Results One thousand nine hundred eighteen women were randomly assigned, and 1,428 women completed the baseline QOL assessment. Compliance with QOL measures was > 85%. Baseline summary scores for the SF-36 physical component summary (47.5 for letrozole and 47.9 for placebo) and mental component summary (55.5 for letrozole and 54.8 for placebo) were close to the population norms of 50. No differences were seen between groups in mean change scores for the SF-36 physical and mental component summaries and the other eight QOL domains except for the role-physical subscale. No difference was found in any of the four domains of the MENQOL Conclusion No clinically significant differences were seen in overall QOL measured by the SF-36 summary measures and MENQOL between the letrozole and placebo groups. The data indicate that continuation of aromatase inhibitor therapy after 5 years of prior treatment in the trial population was not associated with a deterioration of overall QOL.
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Oh, Tae Ryom, Hong Sang Choi, Sang Heon Suh, Chang Seong Kim, Eun Hui Bae, Suah Sung, Seung Hyeok Han, Kook Hwan Oh, Seong Kwon Ma, and Soo Wan Kim. "The Association between Health-Enhancing Physical Activity and Quality of Life in Patients with Chronic Kidney Disease: Propensity Score Matching Analysis." International Journal of Environmental Research and Public Health 19, no. 3 (January 25, 2022): 1318. http://dx.doi.org/10.3390/ijerph19031318.
Повний текст джерелаАнотація:
We investigate the association between health-enhancing physical activity and the quality of life in patients with non-dialysis chronic kidney disease. We performed data analysis on 1618 of 2238 patients from 2011 to 2016, obtained from the KoreaN Cohort Study for Outcome in Patients with Chronic Kidney Disease (KNOW-CKD). Health-related quality of life was measured using the Korean version 1.3 of Kidney Disease Quality of Life short-form questionnaire. Health-enhancing physical activity was defined as 150 min of moderate-intensity or 75 min of vigorous-intensity aerobic physical activity throughout the week. Propensity score matching analysis and linear regression was performed to estimate the effect of health-enhancing physical activity on health-related quality of life. The estimate of average treatment effects was 2.60 in the kidney component summary score, 4.45 in the physical component summary score, and 4.24 in the mental component summary score. In all component summary scores and most of their subscales, health-enhancing physical activity showed a significant association with health-related quality of life. Subgroup and sensitivity analyses also showed robust results. This study suggests that health-enhancing physical activity elevated quality of life in patients with non-dialysis chronic kidney disease. The results can contribute to encourage physical activity in patients with chronic kidney disease.
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Rauck, MD, Richard L., Stephen A. Bookbinder, MD, Timothy R. Bunker, MD, Christopher D. Alftine, MD, Steven Gershon, MD, Egbert De Jong, MD, Andres Negro-Vilar, MD, PhD, and Richard Ghalie, MD. "A randomized, open-label, multicenter trial comparing once-a-day AVINZA® (morphine sulfate extended-release capsules) versus twice-a-day OxyContin® (oxycodone hydrochloride controlled-release tablets) for the treatment of chronic, moderate to severe low back pain: Improved physical functioning in the ACTION trial." Journal of Opioid Management 3, no. 1 (January 1, 2007): 35. http://dx.doi.org/10.5055/jom.2007.0037.
Повний текст джерелаАнотація:
This multicenter trial compared the efficacy, safety, and effect on quality of life and work limitation of once-daily extended-release morphine sulfate capsules (AVINZA9, A-MQD) and twice-daily controlled-release oxycodone HCl tablets (OxyContin9, O-ER) in subjects with chronic, moderate to severe low back pain. After randomization and a period of opioid dose titration, subjects (n = 266) underwent an eight-week evaluation phase and an optional four-month extension phase (n = 174 in extension phase). Subjects were assessed using the 12-item Short-Form Health Survey9 (SF-12) and the Work Limitations Questionnaire9 (WLQ). In both groups, significant improvements were observed in the SF-12 mean scores for physical functioning (p < 0.001), role physical (p < 0.0001), bodily pain (p < 0.0001), physical summary (p < 0.001), and mental component summary (p < 0.005). At the end of the titration period, greater relative improvements from baseline were seen in the SF-12 section on physical components in the A-MQD group versus the O-ER group, with significant differences observed for physical functioning (p = 0.0374), role physical (p = 0.0341), bodily pain (p = 0.0001), and physical summary (p = 0.0022). In both groups, SF-12 mean scores improved significantly for mental health (p < 0.01), role emotional (p < 0.01), social functioning (p < 0.0005), vitality (p < 0.005), and the mental component summary (p < 0.005), but no significant differences were noted between the two groups. Both groups reported improvement from baseline in WLQ physical demands scores, with no significant differences noted between the two groups. At the end of the evaluation phase, fewer subjects were unable to work due to illness or treatment in the A-MQD group than in the OER group (8.5percent versus 19.4percent, respectively; p = 0.0149). In conclusion, compared to twice-daily OxyContin, once-daily AVINZA resulted in significantly better and earlier improvement of physical function and ability to work.
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Cingolani, Arianna, Danilo Paduano, Valentina Vecchiarelli, Manuela Demelas, Paola Teresa Corrias, Laura Casula, and Paolo Usai. "Feasibility of Low Fermentable Oligosaccharide, Disaccharide, Monosaccharide, and Polyol Diet and Its Effects on Quality of Life in an Italian Cohort." Nutrients 12, no. 3 (March 8, 2020): 716. http://dx.doi.org/10.3390/nu12030716.
Повний текст джерелаАнотація:
The low Fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet has demonstrated excellent results in terms of symptom control and health-related quality of life (HRQoL) in irritable bowel syndrome (IBS) sufferers, but patients have complained about unsatisfying taste, difficulty in following the diet, and time consumption. To investigate the feasibility of the low FODMAP diet in an Italian (Sardinian) cohort, sixty consecutive eligible outpatients (11 men and 49 women) with IBS were enrolled and followed a low FODMAP diet (gluten allowed, restriction phase of four weeks, reintroduction phase of four weeks). Food habits were assessed using 24-hour dietary recall, Bristol Stool Scale for stool consistency, Visual Analogue Scale for abdominal bloating, VAS (Visual Analogue Scale) for abdominal pain, IBS Severity Scoring System for perceived disease severity, and a 12-item Short Form Survey for HRQoL (psychological component summary + mental component summary) were applied at baseline (T0) and at the end of each phase (T1-four weeks and T2-eight weeks). Statistical analysis was performed by dividing the cohort into diarrhoea-dominant IBS (IBS-D) and other IBS subtypes (selected IBS-others). Comparisons between T1 and T2 vs. T0 and T2 vs. T1 were performed. The low FODMAP diet lowered VASp (VAS pain), VASb (VAS bloating), and IBS SSS (IBS Severity Scoring System), and increased PCS (Physical Component Summary) and MCS (Mental Component Summary) in both subgroups. Bristol Stool Scale (BSS) only improved in the IBS-D subgroup. The dropout mean values for MCS were higher than treated subjects and the percentage of unemployment was lower in the dropouts. According to the dropout features, the low FODMAP diet seems to show greater feasibility for patients with more time to dedicate to the diet (unemployed, homemakers, housewives, or students), more motivation, and more severe clinical features, independent of their place of residence.
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Zhao, Min-Chao, Kai Yang, Bao-Hui Yang, Shuai Guo, Ya-Ping Wang, Xiao-Wei Zhang, and Hao-Peng Li. "Prognosis of C4 dislocation with spinal cord injury following psychological intervention." Journal of International Medical Research 49, no. 4 (April 2021): 030006052110045. http://dx.doi.org/10.1177/03000605211004520.
Повний текст джерелаАнотація:
Objective To investigate the effect of psychological intervention on the prognosis of patients with C4 dislocation and spinal cord injury. Methods We investigated target patients admitted between 2010 and 2018. Patients’ mental state, quality of life and neurological function at different time points were evaluated to examine the relationship between psychological intervention and recovery and prognosis of acute and critical spinal cord injury. Results All patients showed improvements in clinical symptoms, neurological function and quality of life. Psychological intervention significantly improved Zung Self-Rating Anxiety Scale score, Zung Self-Rating Depression Scale score and SF-36 Mental Component Summary score within 3 months. Japanese Orthopaedic Association neurological function score and SF-36 Physical Component Summary score were significantly improved after 1-year follow-up. Psychological intervention did not improve 2-year survival. Conclusion Timely and professional psychological intervention can eliminate the psychological disorders of C4 dislocation patients with spinal cord injury. This has a positive effect on their quality of life and prognosis.