Добірка наукової літератури з теми "Medulloblastoma paediatric"
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Статті в журналах з теми "Medulloblastoma paediatric":
Tan, Geok Chin. "Molecular Subtyping of Paediatric Medulloblastoma by Immunohistochemistry." Medicine & Health 15, no. 2 (December 31, 2020): 124–39. http://dx.doi.org/10.17576/mh.2020.1502.13.
Abbas, Zahra, Jessica Buck, Mathew Ancliffe, Clara Andradas Arias, Meegan Howlett, Hilary Hii, Terrance Johns, Siddhartha Mitra, Nicholas Gottardo, and Raelene Endersby. "MODL-18. Enhancing anti-CD47 mAb efficacy with radiotherapy for Group 3 paediatric medulloblastoma in preclinical models." Neuro-Oncology 24, Supplement_1 (June 1, 2022): i172—i173. http://dx.doi.org/10.1093/neuonc/noac079.641.
Lasseini, Ali, Aliyu Muhammad Koko, and Ashafa Birnin Gwari Isa. "Demographic and Interventional Pattern of Pediatric Brain Tumors Managed at UDUTH Sokoto: A Decade Review." International Journal of Research and Review 10, no. 10 (October 21, 2023): 374–77. http://dx.doi.org/10.52403/ijrr.20231045.
Tang, Phua Hwee, Sharon Low, Enrica Tan, and Kenneth Chang. "IMG-01. DWI RATIO OF HISTOLOGICAL MOLECULAR SUBTYPES OF PAEDIATRIC MEDULLOBLASTOMAS." Neuro-Oncology 22, Supplement_3 (December 1, 2020): iii354. http://dx.doi.org/10.1093/neuonc/noaa222.337.
Grosshans, David R. "Proton therapy for paediatric medulloblastoma." Lancet Oncology 17, no. 3 (March 2016): 258–59. http://dx.doi.org/10.1016/s1470-2045(15)00217-x.
Burki, Talha Khan. "Postoperative radiotherapy for paediatric medulloblastoma." Lancet Oncology 17, no. 9 (September 2016): e381. http://dx.doi.org/10.1016/s1470-2045(16)30390-4.
Padovani, L., G. Horan, and T. Ajithkumar. "Radiotherapy Advances in Paediatric Medulloblastoma Treatment." Clinical Oncology 31, no. 3 (March 2019): 171–81. http://dx.doi.org/10.1016/j.clon.2019.01.001.
McLendon, Friedman, Fuchs, Kun, and Bigner. "Diagnostic markers in paediatric medulloblastoma: a Paediatric Oncology Group Study." Histopathology 34, no. 2 (February 1999): 154–62. http://dx.doi.org/10.1046/j.1365-2559.1999.00577.x.
Wong, Gabriel Chun-Hei, Queenie Junqi Huang, Manix Fung Man Poon, Nellie Yuk-Fei Chung, Queenie Hoi-Wing Wong, Zhen-Yu Zhang, Zhi-Feng Shi, et al. "PATH-32. CLINICAL AND MUTATIONAL PROFILES OF ADULT MEDULLOBLASTOMA GROUPS." Neuro-Oncology 22, Supplement_2 (November 2020): ii171. http://dx.doi.org/10.1093/neuonc/noaa215.713.
Allen, Joseph, Susannah Entwistle, Beth Coyle, and Alistair N. Hume. "MDB-46. ARE RAB40 SMALL GTPASES DRIVERS OF MEDULLOBLASTOMA PATHOGENESIS?" Neuro-Oncology 26, Supplement_4 (June 18, 2024): 0. http://dx.doi.org/10.1093/neuonc/noae064.495.
Дисертації з теми "Medulloblastoma paediatric":
Nasir, Aishah. "An investigation of metastatic markers in models of paediatric medulloblastoma." Thesis, University of Nottingham, 2017. http://eprints.nottingham.ac.uk/42405/.
Mather, Rebecca Louise. "Deacetylation of GD3A as a potential therapeutic strategy for paediatric medulloblastoma." Thesis, University of Portsmouth, 2016. https://researchportal.port.ac.uk/portal/en/theses/deacetylation-of-gd3a-as-a-potential-therapeutic-strategy-for-paediatric-medulloblastoma(d5e04f18-7985-48ff-807a-0962e6037835).html.
Nair, Omesan. "Profiling medulloblastoma and juvenile pilocytic astrocytoma brain tumours in a South African paediatric cohort." Doctoral thesis, University of Cape Town, 2017. http://hdl.handle.net/11427/26896.
George, Courtney M. "Medulloblastoma: New animal models, preclinical drug testing, and characterising immune infiltrates." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2022. https://ro.ecu.edu.au/theses/2575.
Okiro, Patricia Opon. "Morphological classification of childhood medulloblastomas with β-catenin immunohistochemistry and mycn fluorescent in situ hybridization". Master's thesis, University of Cape Town, 2015. http://hdl.handle.net/11427/15733.
Penco-Campillo, Manon. "Le VEGFC et les récepteurs CXCR1/2 : des cibles pertinentes pour le traitement des médulloblastomes pédiatriques." Electronic Thesis or Diss., Université Côte d'Azur, 2022. http://www.theses.fr/2022COAZ6025.
Medulloblastoma (MB) is the most common and aggressive pediatric brain tumor. Despite aggressive multimodal treatment, resulting in significant side effects, 30% of patients develop resistance and relapse following the appearance of metastases within 5 years. Recurrences cannot be controlled by conventional (radio- and chemotherapy) or targeted (anti-angiogenic, anti-inflammatory, anti-immune checkpoint) treatments. The objective of my thesis is therefore to discover new targets and relevant therapeutic strategies for these patients at diagnosis or after a relapse.MBs are highly vascularized tumors. The phenomenon of resistance is, in part, linked to the development of blood (angiogenesis) and lymphatic (lymphangiogenesis) vessels in the tumor, which constitute the main routes of metastatic dissemination. The lymphatic growth factor, VEGFC, and its receptors/co-receptors are the major players in lymphangiogenesis. In the first part of my thesis, I showed that VEGFC is inversely correlated to MB cell growth and aggressiveness. Indeed, VEGFC decreases the proliferation and migration of MB cells, as well as their ability to form pseudo-vessels in vitro, by an autocrine signalization. Cells resistant to radiotherapy show elevated levels of VEGFC and lose their ability to migrate and form pseudo-vessels. Irradiation reduces the aggressiveness of MB cells by a VEGFC-dependent process. VEGFC-overexpressing cells and radiation-resistant cells form smaller experimental tumors in nude mice. Thus, VEGC appears to be a negative regulator of MB growth. These results pave the way for the development of pro-VEGFC therapies in these cancers.In the second part of my thesis, I correlated the expression of the ELR+CXCL/CXCR1-2 pro-angiogenic and pro-inflammatory signaling pathway to shorter survival in patients with MB. I showed that a novel pharmacological inhibitor (C29) of CXCR1-2 receptors inhibits proliferation, CXCL8/CXCR1-2-dependent migration, invasion and pseudo-vessel formation by susceptible or resistant MB cells to radiotherapy. C29 reduces the growth of experimental MBs in an ex vivo organotypic mouse model and crosses the blood-brain barrier. Thus, targeting CXCR1-2 represents a promising strategy for the treatment of pediatric MB, at first line or at relapse.Key words: pediatric medulloblastoma, VEGFC/VEGFR, CXCR1-2, ELR+CXCL cytokines, targeted therapy, lymphangiogenesis, angiogenesis
Sorensen, James. "Therapeutic Efficacy of a Co-Q10 Analogue in Combating Cachexia and Mortality Induced by Gold-Standard Paediatric Chemotherapy Regimens." Thesis, 2020. https://vuir.vu.edu.au/41826/.
Книги з теми "Medulloblastoma paediatric":
Taylor, Roger E., Barry L. Pizer, Nancy Tarbell, Alba A. Brandes, and Stephen Lowis. Embryonal and pineal tumours. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199651870.003.0009.
Частини книг з теми "Medulloblastoma paediatric":
Janzen, Laura, and Ute Bartels. "Paediatric Neuro-Oncology: Medulloblastoma." In Physician's Field Guide to Neuropsychology, 133–46. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4939-8722-1_8.
Bellapukonda, Snigdha, and Praneeth Suvvari. "Paediatric Case of Medulloblastoma for Whole Brain Radiotherapy." In Problem Based Learning Discussions in Onco-Anesthesia and Onco-Critical Care, 203–12. Singapore: Springer Nature Singapore, 2024. http://dx.doi.org/10.1007/978-981-99-6339-3_19.
Shahi, Mehdi Hayat. "Mitogen-activated protein (MAP) kinase Roles in Paediatric Brain Tumor “Medulloblastoma”." In Role of Signaling Pathways in Brain Tumorigenesis, 209–18. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-15-8473-2_18.
Nelson, M., C. Diebler, and W. St C. Forbes. "Paediatric medulloblastoma: atypical CT features at presentation in the SIOP II trial." In Proceedings of the XIV Symposium Neuroradiologicum, 516–17. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-49329-4_191.
Talamonti, Cinzia, Stefano Piffer, Daniela Greto, Monica Mangoni, Antonio Ciccarone, Paolo Dicarolo, Maria Evelina Fantacci, et al. "Radiomic and Dosiomic Profiling of Paediatric Medulloblastoma Tumours Treated with Intensity Modulated Radiation Therapy." In Computer Analysis of Images and Patterns, 56–64. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-29930-9_6.
Young, A. "Craniotomy for medulloblastoma." In Paediatric Anaesthesia, 81–85. CRC Press, 2004. http://dx.doi.org/10.3109/9780203413012-15.
Massimino, Maura, Eric Bouffet, and Vijay Ramaswamy. "Embryonal Tumours." In Oxford Textbook of Cancer in Children, 188–97. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198797210.003.0023.
Тези доповідей конференцій з теми "Medulloblastoma paediatric":
Lyman, Stephanie. "730 An exploration of existing and potential novel biomarkers in paediatric medulloblastoma." In Royal College of Paediatrics and Child Health, Abstracts of the RCPCH Conference, Liverpool, 28–30 June 2022. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2022. http://dx.doi.org/10.1136/archdischild-2022-rcpch.495.
Shoji Hayashi, Daniel, Ana Luiza Ongaro Seidinger Conte, Isadora Olenscki Gilli, Gabriel Lopes Centoducatte, and José Andrés Yunes. "Identification of genetic profile associated with response to treatment with protein Smoothened (SMO) inhibitors in paediatric medulloblastoma patients." In XXV Congresso de Iniciação Cientifica da Unicamp. Campinas - SP, Brazil: Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-78106.