Добірка наукової літератури з теми "Medical ozone generator"

Ozone therapy is known to be the current successful method of dialysis which is first taken up in Germany. Medical oxygen known to be an ataxic generator is used to generate medical ozone, ensuring the inert contact of all the materials related to ozone. Surprisingly this useful and effective therapy is not recognised in our country like India but is widely accepted and practised in the countries like South America, Europe, Russia, Thailand, Bulgaria, Indonesia, Cuba, etc.; since over 70 years it is used as a successful method of treating various illnesses; like used to halt the progression of diabetes, Kidney diseases, detoxification of the body, coronary artery disease, etc.; Ozone is prepared freshly "on-site" just before starting the session, as it should be administrated immediately after its generation. They should be accurate, reliable and should project the ozone concentration (1-80μg/ml) as reproducible measurements by using a suitable device. Ozone Therapy has learnt to be an effective therapy for ESRD patients irrespective of the stages of disease dealt. The importance and the applications of Ozone therapy in the current medical field are discussed and emphasised in the present review. This review may help the researchers in planning further research to improvise the therapy or to sophisticate the method of implementation, and it also helps in delivering details of the therapy for better understanding of the medical practitioners.

There is a constant concern about finding new or alternative therapeutical approaches for symptom control and quality of life that are essential in palliative care. Ozone therapy has been studied for over a century, since the development of the first medical ozone-generator able to ensure a correct titration of the ozone-oxygen mixture. When used in precise therapeutic doses O3 prove many consistent and safe therapeutic benefits, with minimal and preventable side actions. Our prospective exploratory study aimed to analyze the effects of ozone therapy administration on palliative care patients, by dynamically monitoring the antioxidant status (superoxide-dismutase and glutathione-peroxidase serum levels), pain perception, and quality of life. The results confirm ozone therapy as a promising alternative adjuvant therapy for increasing the quality of life in palliative care services.

The utilization of ozone is commonly applied in various fields, for instance, it is used as a disinfectant for water treatment, disinfecting, sterilizing medical devices and preserving foodstuffs. Ozone is a nearly colorless gas with a characteristic odor that can be detected by humans up to 0.01 ppm. It can be produced by the dielectric barrier discharge method,which is generally used as a method of generating ozone supplied by high voltage or also called high voltage plasma generators. High voltage plasma occurs in the dielectric barrier discharge air gap, as a result of the air failed in maintaining its insulator properties. The power supply used in this study is a parallel resonant pushpull inverter using a flyback transformer. Furthermore, this study did not use an additional magnetic loudspeaker and used ceramic dielectrics instead. 5 types of ceramics and 2 different types of granite and combined the range of air gap were used during examination and research. The research indicates that the best plasma was found in ceramics 3, 5, granite 1 and 2 with an air gap of 2mm. The current discharge in ceramic 1 with an air gap of 2 mm was higher than the others. The highest voltage discharge was on granite 2 with an air gap of 2 mm. Ceramics 3, 5, granite 1 and 2 with an air gap of 2mm had better ozone concentrations than ceramics 1, 2 and 4.

Abstract Postpartum endometritis is one of the leading causes of infertility in cattle. The study aims to investigate the possibility of using ozonized flaxseed oil (OFO) for treating postpartum purulent-catarrhal endometritis in cows. Ozone was synthesized by using medical ozone generator and chemically pure oxygen. Linseed oil (400.0 ml) was bubbled with an ozone-oxygen mixture for 4 hours through a ceramic sprayer. An ozone concentration at the outlet was 30 mg/l. The therapeutic efficacy of OFO was studied on cattle of the Kholmogory breed with a productivity of 4800 - 5800 kg of milk per year. Thirty animals with symptoms of postpartum purulent-catarrhal endometritis were divided into two groups (n = 15). All of the subjects were in the second and third lactation periods. Animals from both groups were injected with 2% sinestrol solution on days 1 and 3 of treatment. OFO was used in the experimental group (EG). The cattle of the control group (CG) received a 7.5% solution of benzethonium chloride. Drugs were administered intrauterine at a dose of 50–150 ml (depending on the uterus’s size) using a polystyrene pipette, with an interval of 48–72 hours. Cows were inseminated artificially by the cervical method. The pregnancy was determined on the 30-35th day after insemination by ultrasonography. After 5 months of observation, all animals of the CG were pregnant. The pregnancy rate in the EG was 93,3%. In the groups efficiency of the first insemination was 20% and 47%, respectively. In the EG, one impregnation required 1.8±0.2 inseminations, which is 0.5 less than in the CG (2.3±0.3). The duration from calving to impregnation in cows in the EG was 104.4±6.9, 21.2 days less (P < 0.05) than the control, where the period was 125.6±7.6. Thus, OFO can be effectively used for the treatment of endometritis in cattle.

Introduction. Nikola Tesla (1856 - 1943) was a genius inventor and scientist, whose contribution to medicine is remarkable. Part I of this article reviewed special contributions of the world renowned scientist to the establishment of radiology as a new discipline in medicine. This paper deals with the use of Tesla currents in medicine. Tesla Currents in Medicine. Tesla?s greatest impact on medicine is his invention of a transformer (Tesla coil) for producing high frequency and high voltage currents (Tesla currents). Tesla currents are used in diathermy, as they, while passing through the body, transform electrical energy into a therapeutic heat. In 1891, Tesla passed currents through his own body and was the first to experience their beneficial effects. He kept correspondence on electrotherapy with J. Dugan and S. H. Monell. In 1896, he used high frequency currents and designed an ozone generator for producing ozone, with powerful antiseptic and antibacterial properties. Tesla is famous for his extensive experiments with mechanical vibrations and resonance, examining their effects on the organism and pioneering their use for medical purposes. Tesla also designed an oscillator to relieve fatigue of the leg muscles. It is less known that Tesla?s inventions (Tesla coil and wireless remote control) are widely used in modern medical equipment. Apart from this, wireless technology is nowadays widely applied in numerous diagnostic and therapeutic procedures. Conclusion. Nikola Tesla was the last Renaissance figure of the modern era. Tesla bridged three centuries and two millennia by his inventions, and permanently indebted human-kind by his epochal discoveries.

Background.Nosocomial outbreaks of Legionnaires disease have been linked to contaminated water in hospitals. Immunocompromised patients are particularly vulnerable and, when infected, have a high mortality rate. We report the investigation of a cluster of cases of nosocomial pneumonia attributable toLegionella pneumophilaserogroup 1 that occurred among patients on our stem cell transplantation unit.Methods.We conducted a record review to identify common points of potential exposure, followed by environmental and water sampling forLegionellaspecies from those sources. We used an air sampler to in an attempt to detect aerosolizedLegionellaand pulsed-field gel electrophoresis to compare clinical and environmental isolates.Results.The most likely sources identified were the water supply in the patients' rooms and a decorative fountain in the radiation oncology suite. Samples from the patients' rooms did not growLegionellaspecies. Cultures of the fountain, which had been restarted 4 months earlier after being shut off for 5 months, yieldedL. pneumophilaserogroup 1. The isolates from both patients and the fountain were identical by pulsed-field gel electrophoresis. Both patients developed pneumonia within 10 days of completing radiation therapy, and each reported having observed the fountain at close range. Both patients' infections were identified early and treated promptly, and both recovered.Conclusions.This cluster was caused by contamination of a decorative fountain despite its being equipped with a filter and ozone generator. Fountains are a potential source of nosocomial Legionnaires disease despite standard maintenance and sanitizing measures. In our opinion, fountains present unacceptable risk in hospitals serving immunocompromised patients.

Ozone is one of the most powerful oxidizing equipment, so it is effectively used to kill bacteria, viruses, and fungi. Many industrial processes use ozone because ozone can run without forming a by-product in water. Nevertheless, the utilization of ozone in Indonesia has not been applied maximally, due to the large cost of commercial ozonator equipment and operational life that is relatively short. In addition, many still do not comprehensively comprehend the ozonation process that is relatively very fast in the presence of ozone conditions that can only last a few minutes before parsing back into oxygen. In this study, the DBD (Dielectric Barrier Discharge) plasma reactor model with parallel plates for ozone generation at room temperature was developed. Furthermore, this study is more focused on conducting performance tests and optimizing ozone productivity in parallel spacer corona discharge chambers. This designated ozonator was treated as a plasma reactor to perform various tests with varying feed flow rates, input voltages, and gas feeds (compressed air and medical oxygen). After the productivity of the ozonators were tested with iodometric titration method, the ozonator’s productivity in generating ozone and its optimum operating condition were obtained. It can produce up to 0.82 g ozone/h with compressed air feed and 6.45 g ozone/h with medical oxygen feed.

Ozone is a triatomic allotrope of oxygen that can be produced in specially designed machines: ozone generators (ozonators). It breaks down to dioxygen (O2) and active atomic oxygen (O), which is a very strong oxidant. Due to the fact that its bactericidal, virucidal and fungicidal activities are 50 times more powerful than those of chlorine, ozone could be used in a wide range of applications, including disinfection, disinfestation and deodorization. Biochemical properties of ozone make it useful in both human and animal medicine. Ozone therapy has been applied in the treatment of cardiovascular and gastrointestinal tract diseases, many viral, bacterial and fungal infections, corneal diseases, skin disorders, as well as in inflammatory and degenerative joint diseases. Various forms of ozone are utilized for medical purposes, for example, ozone/oxygene mixture, dressing covered with ozonated water or oil, ozonated infusion fluids and ozonated autohemotherapy (AHT). Medical ozone appeared to be successful in the treatment of antibiotic-resistant infections, infected and nonhealing wounds. When properly conducted, ozone therapy is safe and non-toxic, and should therefore be widely used in veterinary and human medicine practice..

Дисертація на здобуття наукового ступеня кандидата технічних наук (доктора філософії) за спеціальністю 05.11.17 «Біологічні та медичні прилади і системи». – Національний технічний університет «Харківський політехнічний інститут», Харків, 2019. Дисертація Махоніна М.В. присвячена вирішенню однієї з актуальних науково-технічних задач сучасного медичного приладобудування – підвищенню ефективності генератору медичного озону за рахунок визначення параметрів розрядної камери, напруги живлення та витрати кисню. На даний час у світі активно використовують озон та його суміші для широких потреб різних галузей. Для отримання озону використовуються спеціальні генератори озону різних типів у залежності від сфери їх застосування. Ці генератори відрізняються розмірами, кількістю озону, що генерується за відрозок часу та інші. Особливістю ж генераторів медичного озону є те, що необхідно підтримувати задані параметри отримуваної озоно-кисневої суміші на протязі усього часу проведення процедури, а у якості робочого газу використовується медичний кисень. Це дозволяє реалізовувати методики озонотерапії для максимально ефективного лікування пацієнтів. Типові параметри озоно-кисневої суміші, які повинен забезпечувати медичний генератор озону регламентуються в Україні «Методиками для застосування озону в медичній практиці», які були затверджені Міністерством охорони здоров’я в 2004 році. Згідно сучасної редакції цих методик концентрація озону в озоно-кисневій суміші повинна змінюватись у діапазоні від 0,1 до 80 мг/л, а витрата суміші від 0,1 до 1 л/хв. Медичні генератори озону активно використовуються у кабінетах озонотерапії та медичних установах України, країн СНД, а також країн Латинської Америки. Щорічно у світі проводиться велика кількість конференцій присвячених озонотерапії, на яких вона отримує свій подальший розвиток Практичне використання генераторів медичного озону свідчить, що більшість апаратури, що використовуються, потребує вдосконалення для забезпечення роботи на основі сучасних медичних рішень у лікуванні. Тобто розробка сучасного генератора потребує не тільки відповідність параметрів сучасним вимогам, а й ще запас на розвиток та можливість збільшення значень концентрації озону. Крім того, у більшості медичних генераторів озону спостерігається невідповідність заявлених параметрів озоно-кисневої суміші та значення продуктивності по озону. Продуктивність генератора озону, в свою чергу, залежить від: параметрів розрядної камери, параметрів напруги живлення, параметрів робочого газу. Вирішенням проблему пошуку оптимальних значень цих параметрів для підвищення ефективності роботи генератора озона займаються багато науковців, серед яких можна виділити японських, німецьких та науковців з країн СНД. Але на даний момент ще не існує універсальної моделі розрахунку параметрів генератору Таким чином, задача підвищення ефективності роботи генератора медичного озону за рахунок визначення найкращих параметрів його вузлів, що дозволить підвищити якість процедур озонотерапії є актуальним і перспективним напрямком розвитку генераторів озону. У дисертаційній роботі вперше побудовано математичну модель синтезу озону в розрядній камері генератора медичного озону, яка враховує вплив не тільки параметрів електричної енергії, а також параметрів розрядної камери та робочого газу. Отримані залежності впливу параметрів електричної енергії на синтез озону у розрядній камері на основі проведеного аналізу та з використанням комп’ютерного моделювання. Отримала подальший розвиток модель процесу генерації озону в бар'єрному розряді, яка, на відміну від існуючої, враховує не тільки параметри напруги живлення і розміри камери, але і процеси, що відбуваються в розрядному проміжку. Запропоновано методику розрахунку основних параметрів генератора озону при його розробці, що дозволяє підвищити ефективність синтезу озону. Практичне значення одержаних результатів полягає у обґрунтованні переліку параметрів, що чинять найбільший вплив на продуктивність генератора медичного озону; інженерних розрахунках параметрів генератора медичного озону, які дозволили оптимізувати конструкцію генератора з заданими параметрами; реалізації експериментального зразка генератора медичного озону з вдосконаленою системою автоматичного регулювання витрати газу, що дозволила забезпечити виконання широко спектру процедур озонотерапії. Отриманні практичні результати дисертаційної роботи впроваджені на НВП «Еконіка» при розробці та виготовлення сучасних генераторів медичного озону, а також розроблений макетний зразок пройшов медичну апробації у медичному центрі «Пульс-медика» та у Інституті медичної радіології ім. С.П. Григор’єва.
Thesis for the degree of candidate of technical sciences (PhD) in the specialty 05.11.17 “Biological and medical devices and systems”. -National Technical University "Kharkov Polytechnic Institute", Kharkov, 2019. The thesis is devoted to the solution of one of the current scientific and technical problems of modern medical instrument making - increasing the efficiency of the medical ozone generator by determining the parameters of the discharge chamber, the supply voltage and the oxygen consumption. Currently, ozone and its mixtures are widely used in the world for the wide range of applications. Different types of ozone generators depending on their application are used for ozone synthesis. These generators differ in size, the amount of ozone generated by the time span, etc. The peculiarity of the generators of medical ozone is that it is necessary to maintain the prescribed parameters of the resulting ozone-oxygen mixture throughout the entire duration of the procedure, and medical oxygen is used as the working gas. This allows us to implement ozone therapy techniques for the most effective treatment of patients. Typical parameters of the ozone-oxygen mixture, which the ozone generating plant should provide, are regulated in Ukraine "Methods for the application of ozone in medical practice", which were approved by the Ministry of Health in 2004. According to the modern version of these methods, the concentration of ozone in the ozone-oxygen mixture should vary in the range from 0.1 to 80 mg / l, and the flow rate of the mixture is from 0.1 to 1 l / min. Medical ozone generators are actively used in the offices of ozonotherapy and medical institutions in Ukraine, CIS countries, as well as Latin American countries. A large number of conferences devoted to ozone therapy are being held annually in the world in which it is further developed. The practical use of generators of medical ozone shows that most of the equipment used needs to be improved to provide work on the basis of modern medical solutions in treatment. That is, the development of a modern generator requires not only compliance with the parameters of modern requirements, but also a stock for development and the possibility of increasing the values of ozone concentration. In addition, in most medical ozone generators there is a discrepancy between the stated parameters of the ozone oxygen mixture and the value of ozone productivity. The performance of the ozone generator, in turn, depends on: the parameters of the discharge chamber, the parameters of the supply voltage, the parameters of the working gas. Many scientists, including Japanese, German and scholars from the CIS countries, are engaged in solving the problem of finding the optimal values of these parameters for increasing the efficiency of ozone generator operation. But at the moment there is still no universal model for calculating the parameters of the ozone generator. Thus, the task of increasing the efficiency of the medical ozone generator by determining the best parameters of its nodes, which will improve the quality of ozone therapy procedures, is an urgent and promising direction for the development of ozone generators. In the dissertation, for the first time, a mathematical model of the synthesis of ozone in a digital chamber of the medical ozone generator was constructed, which takes into account the influence not only of the parameters of electric energy, but also of the parameters of the discharge chamber and the working gas. The dependence of the influence of electric energy parameters on the synthesis of ozone in a discharge chamber was obtained on the basis of the conducted analysis and using computer simulation. The model of the ozone generation process in the barrier discharge has been further developed, which, in contrast to the existing one, takes into account not only the power supply parameters and camera dimensions, but also the processes occurring in the discharge gap. The method of calculation of the basic parameters of the ozone generator during its development, which allows increasing the efficiency of ozone synthesis, is proposed. The practical value of the results obtained is to justify the list of parameters that have the greatest impact on the performance of the medical ozone generator; engineering calculations of parameters of the generator of medical ozone, which allowed to optimize the design of the generator with the given parameters; the implementation of an experimental model of the medical ozone generator with an improved system of automatic regulation of gas consumption, which allowed to ensure the implementation of a wide range of procedures for ozone therapy. The practical results of the dissertation work were introduced at the Scientific-Production Enterprise "Econika" in the development and manufacture of modern generators of medical ozone, and also a prototype sample was developed, was tested at the medical center "Pulse Medika" and at the Institute of Medical Radiology N.A. Grigoriev.

Дисертація на здобуття наукового ступеня кандидата технічних наук за спеціальністю 05.11.17 – біологічні та медичні прилади і системи. Національний технічний університет «Харківський політехнічний інститут», Харків, 2019 р. Дисертацію присвячено розробці методу визначення параметрів генератору медичного озону для ефективного підвищення його продуктивності за рахунок визначення параметрів його частин з урахуванням впливу факторів різної природи. На основі дослідження питання побудови генераторів медичного озону була доведена актуальність дослідження шляхів підвищення його ефективності. Наведені основні фактори, що впливають на продуктивність генератора озону. Запропонована математична модель на основі використання елементарного об’єму , що описує процеси, які відбуваються у розрядній камері при подачі напруги. Розроблено метод визначення параметрів розрядної камери генератору медичного озону, який дозволяє отримати найбільш ефективну конструкцію при заданих режимах роботи. Проведено дослідження розробленної автоматичної системи витрати робочого газу з поліпшеними характеристиками, яка дозволяє здійснювати основні методики озонотерапії. Доведена працездатність даної системи на основі роботи макета генератора медичного озону при проходженні медичної апробації.
Thesis for the degree of candidate of technical sciences in specialty 05.11.17 – biological and medical devices and systems. – National Technical University "Kharkіv Polytechnic Institute", Kharkіv, 2019. The thesis is devoted to the development of a method for determining the parameters of a medical ozone generator to effectively increase its productivity by determining the parameters of its constituent parts, taking into account the influence of factors of different nature. On the basis of the study of the issues of constructing generators of medical ozone, the relevance of the study of ways to increase its efficiency was proved. A mathematical model based on the use of a single volume, which describes the processes occurring in the discharge chamber when the voltage is applied, is proposed. The level of influence of the parameters of the working gas and the geometry of the discharge chamber on the performance of the ozone generator, as well as on the stability of the parameters of the ozone-oxygen mixture, which were set. A method has been developed for calculating the parameters of a discharge chamber of a medical ozone generator, which makes it possible to obtain the most efficient design for given operating modes. A study has been carried out on the development of an automated working gas consumption system with improved characteristics, which makes it possible to carry out the main methods of ozone therapy. The efficiency of this system has been proved on the basis of the work of a medical ozone generator layout during the passage of medical approbation.

The physical environment of western Europe (its air, water, and soil) has been affected by a wide range of pollutants for centuries. Localized pollution of water from anthropogenic sources has been observed since the time of the Roman Empire and by the medieval period cities already experienced air pollution problems. As will be seen, proposals to tackle pollution in the Rhine stretch back to the fifteenth century. However, extensive pollution of the environment was a characteristic of the industrial revolution and major and widespread impacts have been observed throughout the nineteenth and twentieth centuries. Only in the last few decades have the emissions (and, therefore, impacts) of many of these pollutants declined due to measures taken by the countries of the region, both collectively and individually (Farmer 1997). This chapter presents an overview of trends in air, water, and soil pollution. In each case the pollutants of most concern will be discussed, indicating their sources and impacts; locations are indicated in Fig. 19.1. In each case the measures that have been adopted to reduce these pollutants will be described, not least to suggest trends for the future. The monitoring of pollutant emissions, concentrations in the environment, and their specific impacts have generated enormous quantities of data over many years. Basic ‘state of environment’ information is produced at the municipal, regional, national, and international level. The latter includes reports produced by EU institutions, especially the European Commission and the European Environment Agency, as well as other multilateral co-operative institutions such as the Rhine Commission. Severe air pollution sources are concentrated, among other regions, in the traditional heavy industry complexes in north-eastern France, Luxembourg, the Meuse valley in Belgium, and in the huge Ruhr industrial complex in western Germany. The range of air pollutants produced by human activity, as well as the impacts that they cause, are extensive. This section will focus on the following pollutants: ammonia, nitrogen oxides, ozone, particulates, and sulphur dioxide. These result in a range of impacts from direct effects on human health and on vegetation to damage to buildings and materials and acidification and eutrophication of soils and water.