Добірка наукової літератури з теми "Median raphe region"

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Статті в журналах з теми "Median raphe region"

1

Ünal, Betül, Cumhur İbrahim Başsorgun, Meryem İlkay Eren Karanis, and Gülsüm Özlem Elpek. "Perianal Median Raphe Cyst: A Rare Lesion with Unusual Histology and Localization." Case Reports in Dermatological Medicine 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/487814.

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Анотація:
Median raphe cysts present anywhere between the external urethral meatus and the anus. The cysts can occur at parameatus, glans penis, penile shaft, scrotum, or perineum. Perianal region is an extremely rare location for these lesions. Here we present a 50-year-old male patient who presented with a cystic, fluctuant lesion, located at 12 o’clock in perianal region. Microscopic examination revealed a cystic lesion with keratinized and nonkeratinized stratified squamous epithelium, pseudostratified ciliated epithelium, and scattered goblet cells. The final diagnosis of the lesion was median raphe cyst. Ciliated cells and perianal localization in median raphe cysts are extremely rare characteristics.
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2

Chaves, Tiago, Bibiána Török, Csilla Lea Fazekas, et al. "Median raphe region GABAergic neurons contribute to social interest in mouse." Life Sciences 289 (January 2022): 120223. http://dx.doi.org/10.1016/j.lfs.2021.120223.

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3

Nitz, Douglas A., and Bruce L. McNaughton. "Hippocampal EEG and Unit Activity Responses to Modulation of Serotonergic Median Raphe Neurons in the Freely Behaving Rat." Learning & Memory 6, no. 2 (1999): 153–67. http://dx.doi.org/10.1101/lm.6.2.153.

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Hippocampal EEG, GABAergic interneurons, and principal cells were recorded simultaneously as rats foraged within one of three environments both before and after modulation of serotonergic inputs to the hippocampus. Median raphe microinjections of the 5-HT1a receptor agonist 8-OH-DPAT were made to produce inhibition of serotonergic neurons in this region. Such microinjections produced behavioral arousal and increases in the amplitude of hippocampal EEG theta. Consistent with the pattern of serotonergic innervation of the hippocampus, the GABAergic interneuron population was affected differentially by the microinjections. Principal cells were generally unaffected by the manipulation and maintained robust spatial firing correlates within the foraging environment. The results provide basic data on the relationship between serotonergic median raphe neurons and hippocampal activity in a behaving animal. The data suggest that behavioral responses to manipulation of the serotonergic system are mediated by brain regions other than the hippocampus or are mediated through changes in the activity of hippocampal interneurons.
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4

Balázsfi, Diána G., Dóra Zelena, Lívia Farkas, et al. "Median raphe region stimulation alone generates remote, but not recent fear memory traces." PLOS ONE 12, no. 7 (2017): e0181264. http://dx.doi.org/10.1371/journal.pone.0181264.

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5

Sos, Katalin E., Márton I. Mayer, Csaba Cserép, et al. "Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region." Brain Structure and Function 222, no. 1 (2016): 287–99. http://dx.doi.org/10.1007/s00429-016-1217-x.

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6

Park, Min-Young, Jeong-Min Kim, Gun-Wook Kim, et al. "Pigmented Median Raphe Cysts on the Scrotum and Perianal Region: A Case Report." Annals of Dermatology 30, no. 5 (2018): 622. http://dx.doi.org/10.5021/ad.2018.30.5.622.

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7

Szőnyi, András, Krisztián Zichó, Albert M. Barth, et al. "Median raphe controls acquisition of negative experience in the mouse." Science 366, no. 6469 (2019): eaay8746. http://dx.doi.org/10.1126/science.aay8746.

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Adverse events need to be quickly evaluated and memorized, yet how these processes are coordinated is poorly understood. We discovered a large population of excitatory neurons in mouse median raphe region (MRR) expressing vesicular glutamate transporter 2 (vGluT2) that received inputs from several negative experience–related brain centers, projected to the main aversion centers, and activated the septohippocampal system pivotal for learning of adverse events. These neurons were selectively activated by aversive but not rewarding stimuli. Their stimulation induced place aversion, aggression, depression-related anhedonia, and suppression of reward-seeking behavior and memory acquisition–promoting hippocampal theta oscillations. By contrast, their suppression impaired both contextual and cued fear memory formation. These results suggest that MRR vGluT2 neurons are crucial for the acquisition of negative experiences and may play a central role in depression-related mood disorders.
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8

Cudennec, Annie, Danielle Duverger, Eric T. MacKenzie, Bernard Scatton, and André Serrano. "Serotonergic Neuron Stimulation Modulates Thalamocortical Glucose Use in the Conscious Rat." Journal of Cerebral Blood Flow & Metabolism 7, no. 4 (1987): 502–6. http://dx.doi.org/10.1038/jcbfm.1987.94.

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We have studied the effects, in the conscious rat, of electrical stimulation of the dorsal or median raphe nuclei on integrated functional activity, as assessed by the quantitative 2-deoxyglucose autoradiographic technique, Stimulation of serotonergic neurons elicits metabolic changes in cortical and thalamic regions that are not limited to those structures known to receive the densest serotonergic innervation. The thalamic nuclei that are activated by raphe stimulation include those that subserve the processing of somesthetic, accessory visual, and limbic information, Raphe stimulation increased cortical glucose use in a laminar and columnar pattern, but only in a highly circumscribed region that corresponds to the somatotopic representation of the rat's face and head. These findings indicate that ascending serotonergic neurons play an important modulatory role in the regulation of thalamocortical glucose use, observations that may be of value in the understanding of the etiology and expression of classic migraine.
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9

Domonkos, Andor, Litsa Nikitidou Ledri, Tamás Laszlovszky, et al. "Divergent in vivo activity of non‐serotonergic and serotonergic VGluT3–neurones in the median raphe region." Journal of Physiology 594, no. 13 (2016): 3775–90. http://dx.doi.org/10.1113/jp272036.

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10

Le Bars, Pierre, Gaston Niagha, Ayepa Alain Kouadio, et al. "Pilot Study of Laser Doppler Measurement of Flow Variability in the Microcirculation of the Palatal Mucosa." BioMed Research International 2016 (2016): 1–7. http://dx.doi.org/10.1155/2016/5749150.

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Background.Histopathological alterations can arise when the denture-supporting mucosa experiences microbial and mechanical stress through the denture base and diagnosis of these diseases usually follows microvascular changes. Microcirculation measurement could allow for detection of such dysfunction and aid in the early diagnosis of palatal mucosa pathologies.Materials and Methods. We tested the sensitivity of laser Doppler for measuring the microcirculation of the palatal mucosa, assessing the median raphe (MR), Schroeder area (SA), and retroincisive papilla (RP). A Doppler PeriFlux 5000 System, containing a laser diode, was used. 54 healthy participants were recruited. We compare the measurements of PU (perfusion unit) using ANOVA test.Results.The numerical values for palatal mucosa blood flow differed significantly among the anatomical areas (p=0.0167). The mean value of Schroeder area was 92.6 (SD: 38.4) and was significantly higher than the retroincisive papilla (51.9) (SD: 20.2) (p<0.05), which in turn was higher than that of median raphe (31.9) (SD: 24.2) (p<0.0001).Conclusion.Schroeder area appeared to have the greatest sensitivity, and vascular flow variability among individuals was also greatest in this region. We suggest that analysis of blood stream modification with laser Doppler of the palatal mucosa can help to detect onset signs of pathological alterations.
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