Готові списки джерел за темами / MDHAR

Добірка наукової літератури з теми "MDHAR"

Автор: Grafiati

Опубліковано: 17 листопада 2023

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Статті в журналах з теми "MDHAR"

Vanacker, Hélène, Marjorie Guichard, Anne-Sophie Bohrer, and Emmanuelle Issakidis-Bourguet. "Redox Regulation of Monodehydroascorbate Reductase by Thioredoxin y in Plastids Revealed in the Context of Water Stress." Antioxidants 7, no. 12 (December 6, 2018): 183. http://dx.doi.org/10.3390/antiox7120183.

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Thioredoxins (TRXs) are key players within the complex response network of plants to environmental constraints. Here, the physiological implication of the plastidial y-type TRXs in Arabidopsis drought tolerance was examined. We previously showed that TRXs y1 and y2 have antioxidant functions, and here, the corresponding single and double mutant plants were studied in the context of water deprivation. TRX y mutant plants showed reduced stress tolerance in comparison with wild-type (WT) plants that correlated with an increase in their global protein oxidation levels. Furthermore, at the level of the main antioxidant metabolites, while glutathione pool size and redox state were similarly affected by drought stress in WT and trxy1y2 plants, ascorbate (AsA) became more quickly and strongly oxidized in mutant leaves. Monodehydroascorbate (MDA) is the primary product of AsA oxidation and NAD(P)H-MDA reductase (MDHAR) ensures its reduction. We found that the extractable leaf NADPH-dependent MDHAR activity was strongly activated by TRX y2. Moreover, activity of recombinant plastid Arabidopsis MDHAR isoform (MDHAR6) was specifically increased by reduced TRX y, and not by other plastidial TRXs. Overall, these results reveal a new function for y-type TRXs and highlight their role as major antioxidants in plastids and their importance in plant stress tolerance.

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Zhou, Fangfang, Bowen Zheng, Fei Wang, Aiping Cao, Shuangquan Xie, Xifeng Chen, Joel A. Schick, Xiang Jin, and Hongbin Li. "Genome-Wide Analysis of MDHAR Gene Family in Four Cotton Species Provides Insights into Fiber Development via Regulating AsA Redox Homeostasis." Plants 10, no. 2 (January 25, 2021): 227. http://dx.doi.org/10.3390/plants10020227.

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Monodehydroasorbate reductase (MDHAR) (EC1.6.5.4), a key enzyme in ascorbate-glutathione recycling, plays important roles in cell growth, plant development and physiological response to environmental stress via control of ascorbic acid (AsA)-mediated reduction/oxidation (redox) regulation. Until now, information regarding MDHAR function and regulatory mechanism in Gossypium have been limited. Herein, a genome-wide identification and comprehensive bioinformatic analysis of 36 MDHAR family genes in four Gossypium species, Gossypium arboreum, G. raimondii, G. hirsutum, and G. barbadense, were performed, indicating their close evolutionary relationship. Expression analysis of GhMDHARs in different cotton tissues and under abiotic stress and phytohormone treatment revealed diverse expression features. Fiber-specific expression analysis showed that GhMDHAR1A/D, 3A/D and 4A/D were preferentially expressed in fiber fast elongating stages to reach peak values in 15-DPA fibers, with corresponding coincident observances of MDHAR enzyme activity, AsA content and ascorbic acid/dehydroascorbic acid (AsA/DHA) ratio. Meanwhile, there was a close positive correlation between the increase of AsA content and AsA/DHA ratio catalyzed by MDHAR and fiber elongation development in different fiber-length cotton cultivars, suggesting the potential important function of MDHAR for fiber growth. Following H2O2 stimulation, GhMDHAR demonstrated immediate responses at the levels of mRNA, enzyme, the product of AsA and corresponding AsA/DHA value, and antioxidative activity. These results for the first time provide a comprehensive systemic analysis of the MDHAR gene family in plants and the four cotton species and demonstrate the contribution of MDHAR to fiber elongation development by controlling AsA-recycling-mediated cellular redox homeostasis.

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Park, Ae Kyung, Il-Sup Kim, Hackwon Do, Hyun Kim, Woong Choi, Seung-Woo Jo, Seung Chul Shin, Jun Hyuck Lee, Ho-Sung Yoon, and Han-Woo Kim. "Characterization and Structural Determination of Cold-Adapted Monodehydroascorbate Reductase, MDHAR, from the Antarctic Hairgrass Deschampsia Antarctica." Crystals 9, no. 10 (October 18, 2019): 537. http://dx.doi.org/10.3390/cryst9100537.

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Ascorbic acid (AsA) is an abundant component of plants and acts as a strong and active antioxidant. In order to maintain the antioxidative capacity of AsA, the rapid regeneration of AsA is regulated by dehydroascorbate reductase (DHAR) and monodehydroascorbate reductase (MDHAR). To understand how MDHAR functions under extreme temperature conditions, this study characterized its biochemical properties and determined the crystal structure of MDHAR from the Antarctic hairgrass Deschampsia antarctica (DaMDHAR) at 2.2 Å resolution. This allowed for a structural comparison with the mesophilic MDHAR from Oryza sativa L. japonica (OsMDHAR). In the functional analysis, yeast cells expressing DaMDHAR were tolerant to freezing and thawing cycles. It is possible that the expression of DaMDHAR in yeast enhanced the tolerance for ROS-induced abiotic stress.

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Do, Hackwon, Il-Sup Kim, Young-Saeng Kim, Sun-Young Shin, Jin-Ju Kim, Ji-Eun Mok, Seong-Im Park, et al. "Purification, characterization and preliminary X-ray crystallographic studies of monodehydroascorbate reductase fromOryza sativaL.japonica." Acta Crystallographica Section F Structural Biology Communications 70, no. 9 (August 27, 2014): 1244–48. http://dx.doi.org/10.1107/s2053230x14015908.

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Monodehydroascorbate reductase (MDHAR; EC 1.6.5.4) is a key enzyme in the reactive oxygen species (ROS) detoxification system of plants. The participation of MDHAR in ascorbate (AsA) recycling in the ascorbate–glutathione cycle is important in the acquired tolerance of crop plants to abiotic environmental stresses. Thus, MDHAR represents a strategic target protein for the improvement of crop yields. Although physiological studies have intensively characterized MDHAR, a structure-based functional analysis is not available. Here, a cytosolic MDHAR (OsMDHAR) derived fromOryza sativaL.japonicawas expressed usingEscherichia colistrain NiCo21 (DE3) and purified. The purified OsMDHAR showed specific enzyme activity (approximately 380 U per milligram of protein) and was crystallized using the hanging-drop vapour-diffusion method at pH 8.0 and 298 K. The crystal diffracted to 1.9 Å resolution and contained one molecule in the asymmetric unit (the Matthews coefficientVMis 1.98 Å3 Da−1, corresponding to a solvent content of 38.06%) in space groupP41212 with unit-cell parametersa=b= 81.89,c= 120.4 Å. The phase of the OsMDHAR structure was resolved by the molecular-replacement method using a ferredoxin reductase fromAcidovoraxsp. strain KKS102 (PDB entry 4h4q) as a model.

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Truffault, Vincent, Noé Gest, Cécile Garchery, Alexandra Florian, Alisdair R. Fernie, Hélène Gautier, and Rebecca G. Stevens. "Reduction of MDHAR activity in cherry tomato suppresses growth and yield and MDHAR activity is correlated with sugar levels under high light." Plant, Cell & Environment 39, no. 6 (February 10, 2016): 1279–92. http://dx.doi.org/10.1111/pce.12663.

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Yoon, Seo-Kyung, Eung-Jun Park, Eun-Kyung Bae, Young-Im Choi, Joon-Hyeok Kim, and Hyoshin Lee. "Isolation and characterization of a monodehydroascorbate reductase gene in poplar (Populus alba × P. glandulosa)." Journal of Plant Biotechnology 41, no. 4 (December 31, 2014): 194–200. http://dx.doi.org/10.5010/jpb.2014.41.4.194.

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Maynard, Daniel, Vijay Kumar, Jens Spro� та Karl-Josef Dietz. "12-Oxophytodienoic Acid Reductase 3 (OPR3) Functions as NADPH-Dependent α,β-Ketoalkene Reductase in Detoxification and Monodehydroascorbate Reductase in Redox Homeostasis". Plant and Cell Physiology 61, № 3 (13 грудня 2019): 584–95. http://dx.doi.org/10.1093/pcp/pcz226.

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Abstract Arabidopsis (Arabidopsis thaliana) 12-oxophytodienoic acid reductase isoform 3 (OPR3) is involved in the synthesis of jasmonic acid (JA) by reducing the α,β-unsaturated double bond of the cyclopentenone moiety in 12-oxophytodienoic acid (12-OPDA). Recent research revealed that JA synthesis is not strictly dependent on the peroxisomal OPR3. The ability of OPR3 to reduce trinitrotoluene suggests that the old yellow enzyme homolog OPR3 has additional functions. Here, we show that OPR3 catalyzes the reduction of a wide spectrum of electrophilic species that share a reactivity toward the major redox buffers glutathione (GSH) and ascorbate (ASC). Furthermore, we show that 12-OPDA reacts with ASC to form an ASC-12-OPDA adduct, but in addition OPR3 has the ability to regenerate ASC from monodehydroascorbate. The presented data characterize OPR3 as a bifunctional enzyme with NADPH-dependent α,β-ketoalkene double-bond reductase and monodehydroascorbate reductase activities (MDHAR). opr3 mutants showed a slightly less-reduced ASC pool in leaves in line with the MDHAR activity of OPR3 in vitro. These functions link redox homeostasis as mediated by ASC and GSH with OPR3 activity and metabolism of reactive electrophilic species.

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Lunde, Christina, Ute Baumann, Neil J. Shirley, Damian P. Drew, and Geoffrey B. Fincher. "Gene Structure and Expression Pattern Analysis of Three Monodehydroascorbate Reductase (Mdhar) Genes in Physcomitrella patens: Implications for the Evolution of the MDHAR Family in Plants*." Plant Molecular Biology 60, no. 2 (January 2006): 259–75. http://dx.doi.org/10.1007/s11103-005-3881-8.

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Acosta-Motos, José Ramón, Laura Noguera-Vera, Gregorio Barba-Espín, Abel Piqueras, and José A. Hernández. "Antioxidant Metabolism and Chlorophyll Fluorescence during the Acclimatisation to Ex Vitro Conditions of Micropropagated Stevia rebaudiana Bertoni Plants." Antioxidants 8, no. 12 (December 3, 2019): 615. http://dx.doi.org/10.3390/antiox8120615.

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In this study, the functioning of antioxidant metabolism and photosynthesis efficiency during the acclimatisation of Stevia rebaudiana plants to ex vitro conditions was determined. A high percentage of acclimatised plants (93.3%) was obtained after four weeks. According to the extent of lipid peroxidation, an oxidative stress occurred during the first hours of acclimatisation. A lower activity of monodehydroascorbate reductase (MDHAR) than dehydroascorbate reductase (DHAR) was observed after 2 days of acclimatisation. However, after 7 days of acclimatisation, stevia plants activated the MDHAR route to recycle ascorbate, which is much more efficient energetically than the DHAR route. Superoxide dismutase and catalase activities showed a peak of activity after 7 days of acclimatisation, suggesting a protection against reactive oxygen species. Peroxidase activity increased about 2-fold after 2 days of acclimatisation and remained high until day 14, probably linked to the cell wall stiffening and the lignification processes. In addition, a progressive increase in the photochemical quenching parameters and the electronic transport rate was observed, coupled with a decrease in the non-photochemical quenching parameters, which indicate a progressive photosynthetic efficiency during this process. Taken together, antioxidant enzymes, lipid peroxidation, and chlorophyll fluorescence are proven as suitable tools for the physiological state evaluation of micropropagated plants during acclimatisation to ex vitro conditions.

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Liu, Xiumei, Lu Wang, Haoran Cui, Hong Zhu, Sisheng Bi, Zhihao Zhang, Shiyuan Meng, Chengdong Song, Huatian Wang, and Fengyun Ma. "Effects of magnetic treatment on the ascorbate–glutathione cycle and endogenous hormone levels in Populus × euramericana ‘Neva’ under cadmium stress." Canadian Journal of Forest Research 49, no. 9 (September 2019): 1147–58. http://dx.doi.org/10.1139/cjfr-2018-0466.

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Cadmium (Cd) contamination in soil has become a serious worldwide environmental and health problem. Cd is easily taken up by plants and translocated to aboveground tissues. A pot experiment was carried out to explore the role of the ascorbate–glutathione (AsA–GSH) cycle and endogenous hormones in enhancing Cd tolerance and promoting translocation of Cd in one-year-old seedlings of Populus × euramericana ‘Neva’. The antioxidant substances ascorbic acid (AsA), dehydroascorbic acid (DHA), glutathione (GSH), and oxidized glutathione (GSSG); the activities of the antioxidant enzymes ascorbic acid peroxidase (APX), glutathione reductase (GR), monodehydroascorbate reductase (MDHAR), and dehydroascorbic acid reductase (DHAR); the levels of the endogenous hormones indole-3-acetic acid (IAA), abscisic acid (ABA), gibberellin (GA3), and zeatin riboside (ZR); and the contents of malondialdehyde (MDA) and hydrogen peroxide (H2O2) were investigated after 30 days of irrigation with half-Hoagland solution containing 0 or 100 μmol·L–1 Cd(NO3)2 under magnetic treatment (MT) or nonmagnetic treatment (NMT). The results were as follows. (i) Compared with NMT, MT increased the AsA levels in roots compared with those in leaves under Cd stress, whereas it increased the DHA levels in the leaves but decreased the DHA levels in the roots. The GSH and GSSG levels both increased by 8%–151% under MT. (ii) MT inhibited the APX activity in blades and roots, and a similar effect was observed on the foliar activities of GR and MDHAR, with a decrease of 8%–50%; however, MT increased the activation of DHAR in the blades and GR in the roots. In addition, compared with NMT, MT increased the activities of GR, MDHAR, and DHAR by 19%–285% in Populus (poplar). (iii) With the exogenous addition of Cd, the Cd accumulation and biological transport coefficient of Cd from roots to leaves (S/R) were enhanced in poplar, accompanied by increased levels of H2O2 and MDA due to MT. (iv) The levels of IAA, ABA, GA, and ZR were inhibited by 19%–95% in the leaves following MT. In contrast, the levels of these endogenous hormones were increased by 18%–203% in the roots following MT. (v) MT improved the seedling growth of poplar, with an increase of 0.4%–90%, compared with that of the NMT. The ground diameter and number of root tips showed the greatest increases, with average ratios of 29% and 87%, respectively. These results suggested a large increase in AsA and decreases in poplar antioxidant enzymes, especially in the leaves, with a high GSH level. In this review, we concluded that the antioxidant substance GSH plays an important role in the AsA–GSH cycle following exposure to a magnetic field under Cd stress. Additionally, the roots play a major role in eliminating oxygen free radicals by regulating the levels and ratios of various endogenous hormones. Moreover, magnetization could alleviate Cd-induced oxidative stress by stimulating MDHAR, DHAR, and GR activities; enhance the defense capability of the AsA–GSH cycle; and maintain normal physiological metabolism in poplar.

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Більше джерел

Дисертації з теми "MDHAR"

Gest, Noé. "MDHAR3 : une enzyme à l'interface de la défense antioxydante, du métabolisme carboné et de la qualité du fruit chez la tomate." Electronic Thesis or Diss., Avignon, 2012. http://www.theses.fr/2012AVIG0328.

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Chez les plantes, l’étude des antioxydants et des métabolismes associés présente un triple intérêt, en raison (i) des vertus nutritionnelles des antioxydants (ii) de leur implication dans la tolérance au stress et (iii) de leur capacité à réguler des processus cellulaires essentiels. L’enzyme monodehydroascorbate reductase (MDHAR) participe à ce type de métabolisme car elle permet le recyclage de l’ascorbate, un antioxydant majeur, à partir de sa forme oxydée, le monodehydroascorbate. Ce travail de thèse, utilisant la tomate comme modèle d’étude, a consisté à étudier les conséquences d’une modification de l’activité d’une isoforme de MDHAR (MDHAR3) sur la teneur en ascorbate, le développement et la tolérance des fruits au froid. Nous avons identifie une régulation négative de la teneur en ascorbate par MDHAR3 : la sous-expression de cette enzyme augmente les teneurs en ascorbate d’environ 20%, et la surexpression produit un effet inverse, ces deux mécanismes n’apparaissant qu’en condition de forte intensité lumineuse. La sous-expression de MDHAR3 a également réveillé la capacité de cette enzyme à réguler le métabolisme carboné, produisant d’importantes modifications phénotypiques au niveau de la croissance précoce de la plante et de la taille du fruit. Ces résultats suggèrent pour MDHAR3 un rôle de médiateur entre le métabolisme antioxydant et le métabolisme central. Enfin, la caractérisation, en condition de stress au froid, de paramètres physiques et biochimiques de fruits de lignées d’introgression dont l’activité MDHAR3 est modifiée a révélé l’importance d’un système antioxydant efficace dans la tolérance à ce type de stress, en particulier immédiatement après la sortie des fruits du froid
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Частини книг з теми "MDHAR"

Oranskaia, Tatiana. "Muktibodh, Gajnan Mdhav." In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_16435-1.

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Pincus, Theodore, Jacquelin Chua, Martin J. Bergman, Yusuf Yazici, and Kathryn A. Gibson. "PROMs (MDHAQ/RAPID3) and Physician RheuMetric Measures." In Patient Reported Outcome Measures in Rheumatic Diseases, 59–99. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-32851-5_3.

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Oranskaia, Tatiana. "Muktibodh, Gajnan Mdhav: C̃d k mũh ṭeṙh hai." In Kindlers Literatur Lexikon (KLL), 1–2. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_16436-1.

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Senthilkumar, M., N. Amaresan, and A. Sankaranarayanan. "Estimation of Mono-Dehydroascorbate Reductase (MDAR) Activity." In Springer Protocols Handbooks, 107–8. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-1080-0_26.

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Leterrier, Marina, and Olivier Cagnac. "Function of the Various MDAR Isoforms in Higher Plants." In Antioxidants and Antioxidant Enzymes in Higher Plants, 83–94. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-75088-0_5.

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Navas, P., A. Estevez, J. M. Villalba, and M. I. Burón. "Role of Cell Surface on NADH-MDHA-Oxidoreductase: Lectin Inhibition." In Plasma Membrane Oxidoreductases in Control of Animal and Plant Growth, 429. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4684-8029-0_67.

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Gibson, Kathryn A., and Theodore Pincus. "Patient physical function in rheumatoid arthritis." In Oxford Textbook of Rheumatoid Arthritis, 221–50. Oxford University Press, 2020. http://dx.doi.org/10.1093/med/9780198831433.003.0020.

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A patient history is far more prominent in diagnosis and management of rheumatoid arthritis (RA) than in many chronic diseases, such as hypertension and diabetes, in which biomarkers dominate clinical decisions. A patient history traditionally has been termed ‘subjective’, based on narrative descriptions, in contrast to ‘objective’ high-technology laboratory and other measures. Self-report questionnaires provide standard, quantitative, reproducible medical history data, which meet criteria for the ‘scientific method’. Patient self-report scores for physical function distinguish active from control treatment results in RA clinical trials as effectively as laboratory tests, joint counts, or indices which include these measures. Self-report physical function generally is more reproducible than joint counts, and more significant than radiographic scores or laboratory tests in the prognosis of severe RA outcomes of work disability and mortality, providing a prognostic indicator analogous to blood pressure or haemoglobin A1C. Four prominent, feasible self-report questionnaires are the Health Assessment Questionnaire (HAQ), its multidimensional version (MDHAQ), the 36-item Short Form (SF-36), and Patient-Reported Outcomes Measurement Information System (PROMIS). The MDHAQ also includes ‘medical’ information (i.e. self-report joint count, symptom checklist, and medical history). Despite documentation of their scientific value and pragmatic advantages to document relevant information while saving time, patient questionnaires remain regarded primarily as providing ancillary rather than essential information to inform clinical decisions, based in part on perceived barriers concerning feasibility and complexities to interface with electronic medical records. Quantitative assessment of physical function on patient questionnaires prior to every routine rheumatology encounter could improve patient care and outcomes.

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Тези доповідей конференцій з теми "MDHAR"

Yee, Sann Su Su, Khin Mar Soe, and Ye Kyaw Thu. "Myanmar Dialogue Act Recognition (MDAR)." In 2020 IEEE Conference on Computer Applications (ICCA). IEEE, 2020. http://dx.doi.org/10.1109/icca49400.2020.9022856.

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Pincus, Theodore. "AB1225 POSSIBLE EARLY DETECTION OF ADVERSE EVENTS USING REMOTE SYSTEMATIC WEEKLY ELECTRONIC MDHAQ." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.7698.

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Riad, Mariam, Elena Obreja, Isabel Castrejon, and Theodore Pincus. "SAT0579 AN ELECTRONIC MDHAQ (MULTIDIMENSIONAL HEALTH ASSESSMENT QUESTIONNAIRE) GIVES SIMILAR RESULTS TO A PAPER VERSION." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.8040.

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D Filha, Amália Maria F. de S., RAFAELA SILVA GUIMARAES GONÇALVES, Clarice A. Esmeraldo, Rafael A. de A. Santos, Daniel N. Matta, Filipe Mateus Lima, Bruno R. Fontes, and Andrea T. Dantas. "VALIDATION OF THE MDHAQ QUESTIONNAIRE AND CORRELATION OF DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS IN THE OUTPATIENTS RHEUMATOLOGY IN A TERTIARY HOSPITAL." In XXXIX Congresso Brasileiro de Reumatologia. Sociedade Brasileiro de Reumatologia, 2022. http://dx.doi.org/10.47660/cbr.2022.1748.

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Schmukler, J., I. Castrejon, and T. Pincus. "THU0521 A simple index based on scores on a multidimensional health assessment questionnaire (MDHAQ) provides information quite similar to acr criteria for fibromyalgia in routine care." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.4324.

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Riad, Mariam, Isabel Castrejon, Joel Block, and Theodore Pincus. "THU0469 CLUES TO RECOGNIZE SECONDARY FIBROMYALGIA IN PATIENTS WITH OSTEOARTHRITIS ACCORDING TO A FIBROMYALGIA ASSESSMENT SCREENING TOOL OF SCALES ON A MULTIDIMENSIONAL HEALTH ASSESSMENT QUESTIONNAIRE (MDHAQ/FAST3-F)." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5858.

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Pincus, T., S. Jamal, and I. Castrejon. "THU0669 A self-report symptom checklist on a multidimensional health assessment questionnaire (MDHAQ) to capture a “positive review of systems” as a standard, quantitative, and informative “scientific” clue to fibromyalgia similar to modified criteria for fibromyalgia." In Annual European Congress of Rheumatology, EULAR 2018, Amsterdam, 13–16 June 2018. BMJ Publishing Group Ltd and European League Against Rheumatism, 2018. http://dx.doi.org/10.1136/annrheumdis-2018-eular.7524.

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Pincus, Theodore, and Isabel Castrejon. "THU0477 A FIBROMYALGIA ASSESSMENT SCREENING TOOL ON A MULTIDIMENSIONAL HEALTH ASSESSMENT QUESTIONNAIRE (MDHAQ) WHICH DOES NOT INCLUDE A SELF-REPORT PAINFUL JOINT COUNT (PAINFUL JC), FAST3NJC, RECOGNIZES FIBROMYALGIA SIMILARLY TO OTHER FAST3 INDICES WHICH INCLUDE A PAINFUL JC." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.7576.

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Castrejon, Isabel, Mariam Riad, Joel Block, and Theodore Pincus. "AB0804 OSTEOARTHRITIS (OA) PATIENTS WITH LOW BASELINE MULTIDIMENSIONAL HEALTH ASSESSMENT QUESTIONNAIRE/ROUTINE ASSESSMENT OF PATIENT INDEX DATA (MDHAQ/RAPID3) SCORES FOR PAIN, PATIENT GLOBAL ASSESSMENT AND MORNING STIFFNESS ARE SIGNIFICANTLY MORE LIKELY TO IMPROVE OVER THE NEXT 6 MONTHS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5902.

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Castrejon, I., K. Gibson, JA Block, and T. Pincus. "THU0472 FAST3 (fibromyalgia assessment screening test): a composite index based on mdhaq provides clues to the presence of secondary fibromyalgia in patients with a primary diagnosis of rheumatoid arthritis at higher levels than identified in the medical record: a cross sectional study from routine care." In Annual European Congress of Rheumatology, 14–17 June, 2017. BMJ Publishing Group Ltd and European League Against Rheumatism, 2017. http://dx.doi.org/10.1136/annrheumdis-2017-eular.5209.

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