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Добірка наукової літератури з теми "M-NVs"

Автор: Grafiati

Опубліковано: 10 грудня 2022

Оновлено: 28 січня 2023

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Статті в журналах з теми "M-NVs"

Rogers, Stephen, Sandra Sardanelli, and Inga Zasada. "Application of alkaline-stabilised biosolids for Meloidogyne incognita suppression in microplots." Nematology 9, no. 1 (2007): 123–29. http://dx.doi.org/10.1163/156854107779969682.

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AbstractN-Viro Soil (NVS) is an alkaline-stabilised biosolid that has been shown to suppress Meloidogyne incognita. In separate microplot studies, NVS was applied either alone at different rates (0, 25, 50, 75, 100 dry t ha−1), or in combination with M. incognita-resistant and M. incognita-susceptible cultivars, to different M. incognita initial densities (0, 37 500, 75 000 eggs/microplot). NVS suppressed M. incognita. During year 1, increasing rates of NVS resulted in higher soil solution pH and greater M. incognita J2 and egg suppression. Soil solution pH remained higher in NVS-amended plots compared to the unamended control in years 2 and 3. NVS was more effective in reducing moderate than in reducing high initial nematode populations, with 94-100% reduction in egg and juvenile populations compared to 75-79%, respectively. In all experiments, a reduction in nematode populations by NVS, alone or in combination with a resistant cultivar, did not occur consistently in years 2 or 3. Unfortunately, the application rate of NVS required to achieve this reduction in nematode populations is probably not agronomically realistic. Additional research may allow the rate of NVS required to suppress plant-parasitic nematodes to be reduced.

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Waldner, Matthew, Andrea Kinnear, Elhem Yacoub, Tim McAllister, Karen Register, Changxi Li, and Murray Jelinski. "Genome-Wide Association Study of Nucleotide Variants Associated with Resistance to Nine Antimicrobials in Mycoplasma bovis." Microorganisms 10, no. 7 (July 6, 2022): 1366. http://dx.doi.org/10.3390/microorganisms10071366.

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Antimicrobial resistance (AMR) studies of Mycoplasma bovis have generally focused on specific loci versus using a genome-wide association study (GWAS) approach. A GWAS approach, using two different models, was applied to 194 Mycoplasma bovis genomes. Both a fixed effects linear model (FEM) and a linear mixed model (LMM) identified associations between nucleotide variants (NVs) and antimicrobial susceptibility testing (AST) phenotypes. The AMR phenotypes represented fluoroquinolones, tetracyclines, phenicols, and macrolides. Both models identified known and novel NVs associated (Bonferroni adjusted p < 0.05) with AMR. Fluoroquinolone resistance was associated with multiple NVs, including previously identified mutations in gyrA and parC. NVs in the 30S ribosomal protein 16S were associated with tetracycline resistance, whereas NVs in 5S rRNA, 23S rRNA, and 50S ribosomal proteins were associated with phenicol and macrolide resistance. For all antimicrobial classes, resistance was associated with NVs in genes coding for ABC transporters and other membrane proteins, tRNA-ligases, peptidases, and transposases, suggesting a NV-based multifactorial model of AMR in M. bovis. This study was the largest collection of North American M. bovis isolates used with a GWAS for the sole purpose of identifying novel and non-antimicrobial-target NVs associated with AMR.

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Stanly, Christopher, Mariaevelina Alfieri, Alfredo Ambrosone, Antonietta Leone, Immacolata Fiume, and Gabriella Pocsfalvi. "Grapefruit-Derived Micro and Nanovesicles Show Distinct Metabolome Profiles and Anticancer Activities in the A375 Human Melanoma Cell Line." Cells 9, no. 12 (December 21, 2020): 2722. http://dx.doi.org/10.3390/cells9122722.

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Fruit juice is one of the most easily accessible resources for the isolation of plant-derived vesicles. Here we found that micro- and nano-sized vesicles (MVs and NVs) from four Citrus species, C. sinensis, C. limon, C. paradisi and C. aurantium, specifically inhibit the proliferation of lung, skin and breast cancer cells, with no substantial effect on the growth of non-cancer cells. Cellular and molecular analyses demonstrate that grapefruit-derived vesicles cause cell cycle arrest at G2/M checkpoint associated with a reduced cyclins B1 and B2 expression levels and the upregulation of cell cycle inhibitor p21. Further data suggest the inhibition of Akt and ERK signalling, reduced intercellular cell adhesion molecule-1 and cathepsins expressions, and the presence of cleaved PARP-1, all associated with the observed changes at the cellular level. Gas chromatography-mass spectrometry-based metabolomics reveals distinct metabolite profiles for the juice and vesicle fractions. NVs exhibit a high relative amount of amino acids and organic acids whereas MVs and fruit juice are characterized by a high percentage of sugars and sugar derivatives. Grapefruit-derived NVs are in particular rich in alpha–hydroxy acids and leucine/isoleucine, myo-inositol and doconexent, while quininic acid was detected in MVs. Our findings reveal the metabolite signatures of grapefruit-derived vesicles and substantiate their potential use in new anticancer strategies.

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Vaughan, Kathleen, Lena Diaw, Wang Zhengyuan, Chia-Hao Liu, Marci Barr, Deepika Darbari, Kimberley A. Woodhouse, et al. "Comparative Clinical and Gene Expression Analysis of Sickle Cell Anemia and Hemoglobin SC Disease." Blood 124, no. 21 (December 6, 2014): 4059. http://dx.doi.org/10.1182/blood.v124.21.4059.4059.

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Abstract Homozygous hemoglobin (Hb) SS is the most common form of sickle cell disease (SCD), while HbSC represents a third of patients and has been less studied. Despite similarities in pathogenesis, there are significant clinical differences between genotypes. To elucidate any molecular differences, we compared gene expression profiles for HbSS and HbSC using microarrays. The Paxgene (PAX) blood RNA system was used to extract RNA from whole blood, which was then globin reduced. We also isolated peripheral blood mononuclear cell (PBMC) RNA to assess transcript patterns in cell populations lacking erythrocytes and granulocytes. To demonstrate clinical differences, we compared HbSS and HbSC subjects from the Bethesda Sickle Cell Cohort Study (ClinicalTrials.gov identifier: NCT00011648). Hematologic parameters were significantly different, with HbSS having higher leukocytes, lower hematocrit, and higher platelets, reticulocytes and fetal hemoglobin. Significant differences were also observed for transaminases, LDH, bilirubin, creatinine kinase, ESR and ferritin. On the other hand, HbSC patients had higher diastolic blood pressure (P=0.0009), higher SpO2 (P<0.0001), less frequent leg ulcers (Odds Ratio 2.90, 95% CI 1.15-7.35, P=0.008) and more prevalent tricuspid jet velocity above 2.9 m/s (Odds Ratio 5.07, 95% CI 1.75-14.71, P=0.0006). These associations led us to hypothesize that these are distinct forms of SCD whose biological differences might be identified with gene expression profiling. RNA was isolated from ten subjects each with HbSS, HbSC or normal volunteers (NVs) using whole blood, PBMCs and Ficoll purified PBMCs (devoid of platelets). Microarray profiling showed that SCD subjects, regardless of genotype, have significant enrichment in glucose metabolism, cellular respiration, and mitochondrial energy generation pathways compared to NVs. Next, we used hierarchical clustering to distinguish SCD expression profiles from NVs, but we were unable to further distinguish HbSS from HbSC samples using this method. We attribute the above differences between SCD and NV samples to the erythroid cell RNA expression in whole blood. There is significant overlap between the 100 most abundantly expressed transcripts and a published signature in purified reticulocytes. However, no significant differences were observed when comparing SCD and NV samples using PBMCs and Ficoll purified PBMCs. We only observed expression differences comparing HbSS and HbSC at the gene level for ATP1B1 (1.3 fold change, P=1.04E-4), WSB1 (1.3 FC, P=3.64E-3) and IL6ST (1.3 FC, P=1.13E-4), despite the evident hematological and clinical differences. ATP1B1 encodes a small ATPase for Na+/K+ transport and has hardly been explored in hemoglobinopathies. Furthermore, ATP1B1 was highly up-regulated in HbSS patients (against controls) but showed less change in HbSC patients. Our results provide an important first step towards elucidating the molecular pathophysiology that might explain the differences in clinical symptoms and survival between these 2 common forms of SCD. Disclosures No relevant conflicts of interest to declare.

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Sharma, Priyanka, Manoj Sharma, N. Vishnu S. Reddy, and Murali Chintham. "Functional Rejuvenation of Recurrent Laryngeal Nerve after Excision of Parathyroid Cyst: A Case Report and Systematic Review of Literature." An International Journal of Otorhinolaryngology Clinics 12, no. 2 (2020): 31–34. http://dx.doi.org/10.5005/jp-journals-10003-1351.

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ABSTRACT Vocal fold paralysis is a prevalent manifestation of various disorders inclusive of the commonest conditions, such as, cardiothoracic surgeries, head and neck malignancies, whereas parathyroid cysts and cervical osteophytes are the rarest causes of this common presentation. A comprehensive systematic review of the literature was done with keyword “parathyroid cysts causing vocal fold palsy” using MEDLINE, PubMed, additionally following PRISMA 2009 guidelines. A 59-year-old male patient presented with hoarseness of voice with right-sided neck swelling for one year. Excision of swelling adherent to the carotid sheath was done. Postoperative histopathological and biochemical analysis of aspirated fluid was consistent with the parathyroid cyst. Patient is in regular follow-up, and there are no clinical signs of recurrence and there is normal functioning of the affected vocal cord. This report adds to the growing knowledge of rare parathyroid cysts with unusual presentations, along with an understanding of pathophysiology, clinical diagnosis, and recovery options for vocal fold palsy due to lesions in the parathyroid gland. How to cite this article: Reddy NVS, Sharma M, Chintham M, et al. Functional Rejuvenation of Recurrent Laryngeal Nerve after Excision of Parathyroid Cyst: A Case Report and Systematic Review of Literature. Int J Otorhinolaryngol Clin 2020;12(2):31–34.

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McDonald, Ian M., Gavin D. Grant, Michael P. East, Thomas S. K. Gilbert, Emily M. Wilkerson, Dennis Goldfarb, Joshua Beri, et al. "Mass spectrometry–based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells." Journal of Biological Chemistry 295, no. 8 (January 2, 2020): 2359–74. http://dx.doi.org/10.1074/jbc.ra119.011083.

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The maternal embryonic leucine zipper kinase (MELK) has been implicated in the regulation of cancer cell proliferation. RNAi-mediated MELK depletion impairs growth and causes G2/M arrest in numerous cancers, but the mechanisms underlying these effects are poorly understood. Furthermore, the MELK inhibitor OTSSP167 has recently been shown to have poor selectivity for MELK, complicating the use of this inhibitor as a tool compound to investigate MELK function. Here, using a cell-based proteomics technique called multiplexed kinase inhibitor beads/mass spectrometry (MIB/MS), we profiled the selectivity of two additional MELK inhibitors, NVS-MELK8a (8a) and HTH-01-091. Our results revealed that 8a is a highly selective MELK inhibitor, which we further used for functional studies. Resazurin and crystal violet assays indicated that 8a decreases triple-negative breast cancer cell viability, and immunoblotting revealed that impaired growth is due to perturbation of cell cycle progression rather than induction of apoptosis. Using double-thymidine synchronization and immunoblotting, we observed that MELK inhibition delays mitotic entry, which was associated with delayed activation of Aurora A, Aurora B, and cyclin-dependent kinase 1 (CDK1). Following this delay, cells entered and completed mitosis. Using live-cell microscopy of cells harboring fluorescent proliferating cell nuclear antigen, we confirmed that 8a significantly and dose-dependently lengthens G2 phase. Collectively, our results provide a rationale for using 8a as a tool compound for functional studies of MELK and indicate that MELK inhibition delays mitotic entry, likely via transient G2/M checkpoint activation.

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Vellios, Nikos, and Panos Tsakiropoulos. "The Effect of Fe Addition in the RM(Nb)IC Alloy Nb–30Ti–10Si–2Al–5Cr–3Fe–5Sn–2Hf (at.%) on Its Microstructure, Complex Concentrated and High Entropy Phases, Pest Oxidation, Strength and Contamination with Oxygen, and a Comparison with Other RM(Nb)ICs, Refractory Complex Concentrated Alloys (RCCAs) and Refractory High Entropy Alloys (RHEAs)." Materials 15, no. 17 (August 23, 2022): 5815. http://dx.doi.org/10.3390/ma15175815.

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In this work, the RM(Nb)IC alloy Nb–30Ti–10Si–5Cr–5Sn–3Fe–2Al–2Hf (NV2) was studied in the as-cast and heat-treated conditions; its isothermal oxidation at 700, 800 and 900 °C and its room temperature hardness and specific strength were compared with other Sn-containing RM(Nb)ICs—in particular, the alloy Nb–24Ti–18Si–5Cr–5Fe–5Sn (NV5)—and with RCCAs and RHEAs. The addition of Fe (a) stabilised Nbss; A15–Nb3X (X = Al, Si and Sn) and Nb3Si; metastable Nb3Si-m’ and Nb5Si3 silicides; (b) supported the formation of eutectic Nbss + Nb5Si3; (c) suppressed pest oxidation at all three temperatures and (d) stabilised a Cr- and Fe-rich phase instead of a C14–Nb(Cr,Fe)2 Laves phase. Complex concentrated (or compositionally complex) and/or high entropy phases co-existed with “conventional” phases in all conditions and after oxidation at 800 °C. In NV2, the macrosegregation of Si decreased but liquation occurred at T >1200 °C. A solid solution free of Si and rich in Cr and Ti was stable after the heat treatments. The relationships between solutes in the various phases, between solutes and alloy parameters and between alloy hardness or specific strength and the alloy parameters were established (parameters δ, Δχ and VEC). The oxidation of NV2 at 700 °C was better than the other Sn-containing RM(Nb)ICs with/without Fe addition, even better than RM(Nb)IC alloys with lower vol.% Nbss. At 800 °C, the mass change of NV2 was slightly higher than that of NV5, and at 900 °C, both alloys showed scale spallation. At 800 °C, both alloys formed a more or less continuous layer of A15–Nb3X below the oxide scale, but in NV5, this compound was Sn-rich and severely oxidised. At 800 °C, in the diffusion zone (DZ) and the bulk of NV2, Nbss was more severely contaminated with oxygen than Nb5Si3, and the contamination of A15–Nb3X was in-between these phases. The contamination of all three phases was more severe in the DZ. The contamination of all three phases in the bulk of NV5 was more severe compared with NV2. The specific strength of NV2 was comparable with that of RCCAs and RHEAs, and its oxidation at all three temperatures was significantly better than RHEAs and RCCAs.

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Donga, R., and J. P. Lund. "Discharge patterns of trigeminal commissural last-order interneurons during fictive mastication in the rabbit." Journal of Neurophysiology 66, no. 5 (November 1, 1991): 1564–78. http://dx.doi.org/10.1152/jn.1991.66.5.1564.

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1. The aim of these experiments was to examine the physiological properties and patterns of firing of trigeminal interneurons during fictive mastication in anesthetized and paralyzed rabbits. Antidromic stimulation was used to show that the 82 interneurons projected to the area of the contralateral fifth nerve motor nucleus (NVmot). 2. Straight-line conduction velocities calculated from stereotaxic coordinates of the stimulating and recording electrodes for 63 interneurons were found to range between 3.7 and 16.3 m/s (mean, 9.5 m/s). 3. Histological reconstructions of recording electrode tracks showed that the interneurons observed in this study were located in the lateral brain stem in or just medial to the rostral trigeminal sensory nuclei, including the intertrigeminal (NVint) and supratrigeminal (NVs) areas, the main sensory nucleus of the fifth nerve (NVsnpr), the rostral subdivision of the oral nucleus of the spinal trigeminal tract (NVor tau), and the rostral part of the parvocellular reticular nucleus (NRpc alpha). 4. Forty-six interneurons were shown to have low-threshold (LT) peripheral receptive fields, and 41 of these (88%) were in the oral cavity. Most of the responses were rapidly adapting. 5. Twenty-eight interneurons changed their pattern of firing during cortically induced fictive mastication. The discharge frequency of 20 neurons varied in phase with the fictive masticatory motor output, which was recorded from central ends of cut hypoglossal nerves (XII) and/or from the NVmot. Others were briefly excited and then inhibited (n = 2), only inhibited (n = 4), or tonically excited during fictive mastication (n = 2). Fifteen others were unaffected by this test. 6. It was found that the rhythmically active neurons could be further subdivided into two categories: those receiving short-latency excitatory input from the masticatory area of the cortex (n = 11) and those that did not (n = 9). No obvious differences in peripheral receptive fields for neurons in these categories were found. 7. We suggest that these phasically active premotor neurons are part of the circuitry generating the rhythmic masticatory pattern, specifically those that directly control the bursts of firing of the trigeminal motoneurons (burst generators, BGs). Their properties allow them to integrate sensory information and descending commands with the masticatory rhythm that is probably generated in midline brainstem reticular nuclei.

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Liu, Gang, Leying Chen, and Shimin Chen. "Zen." Proceedings of the VLDB Endowment 14, no. 5 (January 2021): 835–48. http://dx.doi.org/10.14778/3446095.3446105.

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Emerging Non-Volatile Memory (NVM) technologies like 3DX-point promise significant performance potential for OLTP databases. However, transactional databases need to be redesigned because the key assumptions that non-volatile storage is orders of magnitude slower than DRAM and only supports blocked-oriented access have changed. NVMs are byte-addressable and almost as fast as DRAM. The capacity of NVM is much (4-16x) larger than DRAM. Such NVM characteristics make it possible to build OLTP database entirely in NVM main memory. This paper studies the structure of OLTP engines with hybrid NVM and DRAM memory. We observe three challenges to design an OLTP engine for NVM: tuple metadata modifications, NVM write redundancy, and NVM space management. We propose Zen, a high-throughput log-free OLTP engine for NVM. Zen addresses the three design challenges with three novel techniques: metadata enhanced tuple cache, log-free persistent transactions, and light-weight NVM space management. Experimental results on a real machine equipped with Intel Optane DC Persistent Memory show that Zen achieves up to 10.1x improvement compared with existing solutions to run an OLTP database as large as the size of NVM while achieving fast failure recovery.

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Pacini, G., M. Pendolino, C. Pizzorni, E. Gotelli, A. Sulli, L. Carmisciano, S. Paolino, V. Smith, and M. Cutolo. "POS0850 NAILFOLD CAPILLARY DILATIONS IN RAYNAUD’S PHENOMENON: QUANTIFYING A PREDICTIVE THRESHOLD FOR THE ‘SCLERODERMA PATTERN’." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 679. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2014.

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Background:Non-specific abnormalities could be detected by nailfold videocapillaroscopy (NVC) in subject with primary Raynaud’s Phenomenon (RP) several years before the clinical onset of connective tissue diseases (CTD)s [1]. Previous findings from our group proved that ≤30 μm capillary dilations in RP patients have a negative predictive value for developing the ‘scleroderma pattern’ during follow-up [2].Objectives:To investigate the role of NVC >30 μm capillary dilations as positive predictive factors of the ‘scleroderma pattern’ in RP patients later developing systemic sclerosis (SSc)-related RP.Methods:A 10-year retrospective NVC-based investigation evaluated the dataset of sequential NVCs of 18 RP patients later developing SSc (cases) and 19 sex- and age-matched RP patients later developing other CTDs (controls). Both cases and controls had ≥1 NVC performed before the ‘scleroderma pattern’/CTD diagnosis (basal NVC) showing >30 μm dilated capillaries. Each NVC was qualitatively and semi-quantitatively assessed, recording number of total capillaries, number and average/site-specific diameters (arterial, apical, venous) of >30 μm dilated capillaries [3]. Statistical analysis was performed to stratify the risk of developing the ‘scleroderma pattern’.Results:Significant differences of capillary diameters were observed between cases and controls both at basal NVC and during follow-up (p<0.001). The proportion of >30 μm dilated capillaries in basal NVC was the strongest predictor of ‘scleroderma pattern’ in a median 3-year time, with a 27% cut-off (PPV 0.79, 95%CI 0.54,0.94; p<0.001). Additional “Higher risk” NVC hallmarks for ‘scleroderma pattern’ development were apical diameter >40 μm (p<0.001), venous diameter >25 µm (p<0.05) and average diameter ≥35 µm (p<0.005). Conversely, CTDs patients showed a stable NVC ‘non-scleroderma pattern’ over a median 10-year time.Conclusion:This is the first study to show that NVC-detected homogeneous and progressive capillary loop dilations in RP patients significantly contribute to predict the ‘scleroderma pattern’ evolution within a median 3-year time, possibly providing a “very early” window of opportunity in SSc pre-clinical stages.References:[1]Cutolo M et al. Expert Rev Clin Immunol. 2019;15(7):753–64. [2] Trombetta AC et al. J Rheumatol 2016;43:599–606. [3] Smith et al. Autoimmun Rev 2020; 19(3):102458.Disclosure of Interests:None declared

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Дисертації з теми "M-NVs"

Rosa, Silas Luis Sartori Paschoal da Silva. "Estudo da correlação entre os resultados de testes e a aplicação dos conceitos de Gerenciamento de Projetos para omodelamento matemático da durabilidade de um componente automotivo." Instituto de Matemática, 2012. http://repositorio.ufba.br/ri/handle/ri/21349.

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Existem inúmeras ferramentas para auxliar os engenheiros de CAE no desenvolvimento de novos produtos, como por exemplo: CAD (computer aided design), CAE (computer aided engineering), CAM (computer aided manufacturing), QFD e TRIZ, entre outros. Este trabalho apresenta uma aplicação dos conceitos de gerenciamento de projetos para a simulação computacional da durabilidade virtual afim de auxiliar os profissionais da área de CAE no design de componentes automotivos. Neste trabalho, foram aplicados os conceitos do dFmea para aprimorar os resultados obtidos na utilização dos conceitos do QFD e da TRIZ. Em adicional, serão aplicados os conceitos do diagrama P, matriz morfológica e matriz de Pugh. O método apresentado para aperfeiçoar a durabilidade utiliza a simulação computacional para correlacionar os resultados obtidos com a aplicação das ferramentas de gerenciamento de projetos. Para realizar a simulação computacional foi utilizado o software MSC_Nastran 2004 R2, Sol 103 (modos normais). Apresenta tambem as diferenças entre dois tipos de modelamentos matemáticos utilizando os pontos de fixação da peça avaliada de maneiras diferentes. Por fim, apresenta os resultados dos testes de laboratório, com o objetivo de comprovar a abordagem teórica apresentada nesta dissertação.

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Книги з теми "M-NVs"

Quade, Jack G. Reconnaissance geochemical assessment of mineral resources in Grapevine Canyon G-E-M Resource Area (WSA's NV-O5O-O354 and NV-O5O-O355), West Central Nevada. Reno, Nev: University of Nevada Reno, 1985.

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Frontier cattle ranching in the land and times of Charlie Russell. Montreal: McGill-Queen's University Press, 2004.

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Frontier cattle ranching in the land and times of Charlie Russell. Montréal, QC: McGill-Queen's University Press, 2004.

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Kumar, Anand. Library and Information Science Question Bank : (for NET/SET/JRF Aspirants and Entrance Examinations of M. Phil/Ph. d/NVS/KVS). Ess Ess Publications, 2021.

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Kumar, Anand. Library and Information Science Question Bank : (for NET/SET/JRF Aspirants and Entrance Examinations of M. Phil/Ph. d/NVS/KVS). Ess Ess Publications, 2021.

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LAND.TECHNIK AgEng 2019. VDI Verlag, 2019. http://dx.doi.org/10.51202/9783181023617.

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Dieser VDI-Bericht ist ausschließlich als PDF-Dokument erschienen! Content half of it… Analysis of Drive Trains Model-Based Chiptuning Detection of Diesel Engines 1 M. Hinrichs, P. Pickel, John Deere GmbH, Kaiserslautern R. Isermann, Institute of Automatic Control, Darmstadt An Analysis of the Energy Consumption in the High-Pressure System of an Agricultural Tractor through Modeling and Experiment 9 X. Tian, A. Vacca, Purdue University, West Lafayette, IN, USA; S. Fiorati, F. Pintore, CNH Industrial S.p.A, Modena, Italy Multi-Domain Simulation for the Assessment of the NVH Behaviour of a Tractor with Hydrostatic-Mechanical Power Split Transmission 19 G. Pasch, G. Jacobs, G. Höpfner, J. Berroth, Institute for Machine Elements and Systems Engineering, RWTH Aachen University, Aachen Methods to evaluate steering performance of agricultural tractors 29 S. Liljenberg, M. Frederiksen, T. H. Langer, Danfoss Power Solutions, Nordborg, Denmark Tyres and Soil Soil pressure and pulling be...

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Contributors, See Notes Multiple. The Triumphs of Virtue and Beauty, or, the History of the Life and Adventures of Miss Harriot de M**nv*ll*rs,. Gale ECCO, Print Editions, 2018.

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Stuart, David E. Anasazi America: Seventeen Centuries on the Road from Center Place. University of New Mexico Press, 2014.

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Stuart, David E. Anasazi America: Seventeen Centuries on the Road from Center Place. University of New Mexico Press, 2000.

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Donald, Harris. Master Wеbѕіtеѕ, Uѕеrnаmеѕ and Passwords Sесurity Cоnvеnіеnt Place: Hоw Tо Сrеаtе and Remember yоur Lоgіn Сrеdеntіаlѕ. Independently Published, 2021.

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Частини книг з теми "M-NVs"

Bukharov, Sergey N., Vitaly K. Merinov, Vladimir P. Sergienko, Andrey Ya Grigoriev, and Soyibjon S. Negmatov. "Effect of the M-Phenylenediamine on the Tribotechnical and NVH Characteristics of the Frictional Composite Materials Based on PTFE." In New Technologies, Development and Application IV, 442–49. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-75275-0_49.

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"8.3 Mediopassive (-m-, -η-, -nvy-)." In A Grammar of Tamashek (Tuareg of Mali), 471–76. De Gruyter Mouton, 2005. http://dx.doi.org/10.1515/9783110909586.471.

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"8.4 Reciprocal -nvm-, -m-, -n-." In A Grammar of Tamashek (Tuareg of Mali), 476–81. De Gruyter Mouton, 2005. http://dx.doi.org/10.1515/9783110909586.476.

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Тези доповідей конференцій з теми "M-NVs"

Ohtake, Hiroyasu, and Yasuo Koizumi. "Boiling Heat Transfer Under Oscillatory Flow Condition." In 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/icone14-89582.

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Onset of nucleate boiling (ONB), point of net vapor generation (NVG) and critical heat flux (CHF) on subcooled flow boiling under oscillatory flow, focusing on liquid velocity, amplitude and frequency of oscillations were investigated experimentally and analytically. Experiments were conducted using a copper thin-film and subcooled water in a range of the liquid velocity from 0.27 to 4.07 m/s at 0.10MPa. The liquid subcooling was 20K. Frequency of oscillatory flow was 2, 4 and 6 Hz, respectively; amplitude of oscillatory flow was 25 and 50 % in a ratio of main flow rate, respectively. Temperature at ONB and critical heat flux for oscillatory flow were lower than those for steady flow. The decreasing of liquid velocity by oscillatory caused the ONB and the CHF to decrease. The effects of liquid oscillatory flow on the incipient boiling temperature were examined through a classical stability theory of preexisting nuclei. Heat flux at NVG reduced by superimposed oscillatory flow; the increase of liquid velocity by the oscillatory flow caused the NVG to decrease. The CHF under the oscillatory flow condition was examined analytically by using a liquid sub-layer model and a lumped-heat-capacity model in the heater.

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Tsang, Yuk L., Giri Nallapati, Ron Skarupa, and Brian Anthony. "Identification of Extension Implant Defect in Sub-Micron CMOS ICs – Analysis Technique, Model, and Solution." In ISTFA 2011. ASM International, 2011. http://dx.doi.org/10.31399/asm.cp.istfa2011p0212.

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Abstract A major failure mode known as ROMBIST (logic and memory) that topped the yield loss pareto and plagued a 0.13 m technology chipset production was analyzed. This MCUROM fail exhibited a unique failing pattern where every 4th row failed. A detailed electrical microprobing analysis had led to an exact model that was able to explain the failure mechanism. This model pinpointed a PFET extension implant blockage. Subsequent silicon etch analysis directed by the model prediction brought out the non visual defect (NVD). Inline inspection at the extension implant photo step identified the root cause. A greater than 45% reduction in die cost was realized in lots with photo resist fixes implemented.

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Koul, Dimpy, Ruijun Shen, Tiffany A. LaFortune, Ningyi Tiao, Yong-Wan Kim, Juinn-Lin Liu, Sauveur-Michel Maira, Carlos Garcia-Echeverria, and W. K. Alfred Yung. "Abstract 350: NVP-BKM120: A selective pan-PI3 kinase inhibitor induces G2/M arrest in glioma cell lines via FOXO3a and GADD45a loop." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-350.

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Gobbi, M., F. Giorgetta, P. Guarneri, G. Rocca, and G. Mastinu. "Experimental Study and Numerical Modeling of the Dynamic Behaviour of Tyre/Suspension While Running Over an Obstacle." In ASME 2006 International Mechanical Engineering Congress and Exposition. ASMEDC, 2006. http://dx.doi.org/10.1115/imece2006-14804.

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Simulation tools have been widely used to complement experimentation for suspension design in the automotive industry not only for reducing the development time, but also to allow the optimization of the vehicle performance. Both a test method and a simulation tool are presented for the analysis of Noise-Vibration-Harshness (NVH) performances of road vehicles suspension systems. A single suspension (corner) has been positioned on a rotating drum (2.6 m diameter) installed in the Laboratory for the Safety of Transport of the Politecnico di Milano. The suspension system is excited as the wheel passes over different cleats fixed to the working surface of the drum. The forces and the moments acting at the suspension-chassis joints are measured up to 250 Hz by means of five six-axis load cells. A mathematical representation that can accurately reflect tyre dynamic behaviour while passing over different cleats is fundamental for evaluating the suspension system quality (NVH) and for developing new suspension design and control strategies. Since the phenomenon is highly non-linear, it is rather difficult to predict the actual performance by using a physical model. However universal "black-box" models can be successfully used in the identification and control of non-linear systems. The paper deals with the simulation of the tyre/suspension dynamics by using Recurrent Neural Networks (RNN). RNN are derived from the Multi Layer Feed-forward Neural Networks (MLFNN), by adding feedback connections between output and input layers. The Neural Network (NN) has been trained with the experimental data obtained in the laboratory. The results obtained from the NN demonstrate very good agreement with the experimental results over a wide range of operation conditions. The NN model can be effectively applied as a part of vehicle system model to accurately predict elastic bushings and tyre dynamics behaviour.

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Yang, Jing, and Luis San Andrés. "Making Better Swirl Brakes Using Computational Fluid Dynamics: Performance Enhancement From Geometry Variation." In ASME Turbo Expo 2021: Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/gt2021-58956.

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Abstract A fluid with a large swirl (circumferential) velocity entering an annular pressure seal influences the seal cross-coupled dynamic stiffness coefficients and hence it affects system stability. Typically comprising a large number of angled vanes around the seal circumference, a swirl brake (SB) is a mechanical element installed to reduce (even reverse) the swirl velocity entering an annular seal. SB design guidelines are not readily available and existing configurations appear to reproduce a single source. By using a computational fluid dynamics (CFD) model, the paper details a process to engineer a SB upstream of a sixteen-tooth labyrinth seal (LS) with tip clearance Cr = 0.203 mm. The process begins with a known nominal SB* geometry and considers variations in vane length (LV* = 3.25 mm) and width (WV* = 1.02 mm), and stagger angle (θ* = 0°). The vane number NV* = 72 and vane height HV* = 2.01 mm remain unchanged. The SB-LS operates with air supplied at pressure PS = 70 bar, a pressure ratio PR = exit pressure Pa / PS = 0.5, and rotor speed Ω = 10.2 krpm (surface speed ΩR = 61 m/s). Just before the SB the pre-swirl velocity ratio = average circumferential velocity U / shaft surface speed (ΩR) equals α = 0.5. For the given conditions, an increase in LV allows more space for the development of vortexes between two adjacent vanes. These are significant to the dissipation of fluid kinetic energy and thus control the reduction of α. A 42% increase in vane length (LV = 4.6 mm) produces a ∼ 43% drop in swirl ratio at the entrance of the LS (exit of the SB), from αE = 0.23 to 0.13. Based on the SB with LV = 4.6 mm, the stagger angle θ varies from 0° to 50°. The growth in angle amplifies a vortex at ∼ 70% of the vane height while it weakens a vortex at 30% of HV. For θ = 40°, the influence of the two vortexes on the flow produces the smallest swirl ratio at the LS entrance, αE = −0.03. For a SB with LV = 4.6 mm and θ = 40°, the vane width WV varies from 0.51 mm to 1.52 mm (± 50% of WV*). A reduction in WV provides more space for the strengthening of the vortex between adjacent vanes. Therefore, a SB with greater spacing of vanes also reduces the inlet circumferential velocity. For WV = 0.51 mm, αE further decreases to −0.07. Besides the design condition (α = 0.5), the engineered SB having LV = 4.6 mm, θ = 40° and WV = 0.51 mm effectively reduces the circumferential velocity at the LS entrance for other inlet pre-swirl ratios equaling α = 0 and 1.3. Rather than relying on extensive experiments, the CFD analysis proves effective to quickly engineer a best SB configuration from the quantification of performance while varying the SB geometry and inlet swirl condition.

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