Дисертації з теми "LPP protocol"
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Pamboris, Andreas. "LDP location discovery protocol for data center networks /." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1467934.
Повний текст джерелаTitle from first page of PDF file (viewed September 17, 2009). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 47).
Müller, Morvan Daniel. "Uma solução de autenticação fim a fim para o LDP (Label Distribution Protocol)." Florianópolis, SC, 2002. http://repositorio.ufsc.br/handle/123456789/101540.
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Este trabalho propõe uma solução de autenticação para o protocolo LDP (Label Distribution Protocol) que tem por objetivo autenticar, em um escopo fim a fim, o estabelecimento de um LSP (Label Switching Path) entre um LSR (Label Switching Router) de Ingresso e o seu respectivo LSR de Egresso. Objetiva-se suprir a deficiência do protocolo LDP de não possuir um mecanismo de autenticação fim a fim definido, aplicável entre LSRs não-adjacentes. Conforme foi verificado pelo levantamento de trabalhos correlatos, atualmente é desconhecida uma solução de autenticação semelhante, que efetivamente atenda o propósito de autenticar num escopo fim a fim, o estabelecimento de LSPs no protocolo LDP. Dessa forma a solução deste trabalho é inédita no seu escopo de aplicação. A solução foi planejada para ambientes onde LSPs atravessam múltiplos domínios externos, não confiáveis entre si, e que por isso necessitam de um mecanismo de autenticação durante o estabelecimento dos LSPs. A solução faz uso de um mecanismo de autenticação, baseado em criptografia assimétrica (chave pública e privada), anexado a cada mensagem LDP. Este mecanismo possibilita ao LSR receptor verificar e autenticar o originador da mensagem LDP. Adicionalmente a solução provê integridade de dados através de um mecanismo de resumo de mensagens (hash) e também protege contra ataques de repetição através da inserção de um nonce às mensagens LDP.
Sant'Anna, Thaís Jordão Perez. "Criação do Londrina Activities of Daily Living Protocol (LAP) e a relação entre a dessaturação de oxigênio durante o protocolo e na vida diária em pacientes com DPOC." Universidade Estadual de Londrina. Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências da Saúde, 2015. http://www.bibliotecadigital.uel.br/document/?code=vtls000203844.
Повний текст джерелаBackground: Patients with chronic obstructive pulmonary disease (COPD) present pathophysiological pulmonary and extra-pulmonary features which could lead to the occurrence of hypoxemia. Hypoxemia can lead to negative influence on the outcomes of the diseases natural course, and can be represented by oxygen desaturation assessed by pulse oximetry. Additionally, COPD manifestations lead to symptoms such as dyspnea and fatigue which can impair activities of daily living (ADL) performance in these patients. However, methods for ADL assessment in patients with COPD present some limitations. Furthermore, it is not clear whether possible episodes of oxygen desaturation during an ADL laboratory-based protocol present association with episodes of oxygen desaturation in daily life in this population. Objectives: To develop a new protocol to evaluate ADL performance in patients with COPD (Londrina ADL Protocol [LAP]) and to assess the criterion validity and the reliability of the protocol in the same population. Additionally, to investigate the relationship between oxygen desaturation during the protocol and in patients daily life. Methods: In the first study, a bibliographic research and meetings among the authors of the present study were done to establish the activities to be included in the new protocol (LAP). After defining the protocol, 20 patients with COPD were submitted to four repetitions of the LAP, besides the assessment of quality of life and functional status by questionnaires, functional exercise capacity by the Six-minute Walking Test (6MWT) and physical activity in daily life (PADL) by motion sensors. In the second study, 20 patients with COPD were submitted to pulse oximetry while performing the LAP and during 48 hours in daily life, with simultaneous PADL monitoring. Results: In the first study, the composition of the LAP was defined including five activities based on ADL, involving movements of upper limbs, lower limbs and trunk flexion/inclination. The LAP was reliable (ICC>0.90, P<0.001). Movement intensity during the LAP was highly correlated with movement intensity during daily life (r=0.71). Performance in the LAP was correlated with functional status and quality of life outcomes (0.32 ≤ r ≤ 0.59) and with the distance walked in the 6MWT (r = -0,64). In the second study, the episodes of oxygen desaturation during the LAP were correlated with episodes of oxygen desaturation in daily life (0,45 ≤ r ≤ 0,59). Conclusions: The LAP is a valid and reliable protocol to evaluate ADL performance in patients with COPD. Episodes of oxygen desaturation during an ADL laboratory-based protocol are moderately related to episodes of oxygen desaturation in daily life in this population.
Ártico, Adriana Felix Roberto [UNESP]. "Implementação do protocolo LMP de gerência de enlace em redes GMPLS ópticas." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/98697.
Повний текст джерелаO presente trabalho descreve a implementação open-source do Protocolo de Gerência de Enlace denominado LMP (Link Management Protocol), baseado na RFC 4204. Este protocolo faz parte da arquitetura GMPLS (Generalized Multi-Protocol Label Switching), responsável por gerenciar de forma automatizada as redes ópticas. O protocolo LMP, quando utilizado em conjunto com o pacote open-source DRAGON, disponibiliza ferramentas de gerenciamento distribuído apropriadas para uso em ambientes GMPLS. Neste contexto, ferramentas de roteamento distribuído, estabelecimento rápido de conexões por meio de sinalização e descoberta de serviços podem ser utilizadas. A integração do protocolo LMP open source, no contexto do pacote DRAGON, em equipamentos denominados ROADM (Multiplexador de Inserção/Remoção Óptico Reconfigurável) representa uma plataforma completa para o gerenciamento automatizado de redes ópticas. Embora existam iniciativas de implementação de equipamentos ROADM nacionais, o protocolo LMP para tais plataformas, na forma open source, ainda não foi disponibilizado. Neste sentido, o presente trabalho traz uma contribuição para tal integração, disponibilizando o referido protocolo, para uso com o pacote DRAGON. Foram realizados testes no Laboratório LACE com o protocolo LMP inserido no pacote DRAGON. Os resultados experimentais obtidos comprovaram as funcionalidades do protocolo relacionadas ao estabelecimento, manutenção e gerenciamento do canal de controle, além da identificação das propriedades dos nós adjacentes e isolação de falhas simples ou múltiplas no domínio óptico do gerenciamento do enlace. Tais características, são essenciais para o funcionamento completo do gerenciamento GMPLS, o qual permite a automação total de plataformas de redes ópticas
This dissertation describes the open-source implementation of the Link Management Protocol denominated LMP (Link Management Protocol), based on RFC 4204. This protocol is part of the GMPLS (Generalized Multi-Protocol Label Switching) architecture responsible for managing automatable fiber-optic netwoks. The Protocol LMP, when used together with the package open-source DRAGON, provides tools of management distributed appropriate for use in environments GMPLS. In this context, tools of distributed routing, fast connection establishment via signalling and service discovery can be used. The integration of open source protocol LMP, in the context of package DRAGON, in called equipment ROADM (Reconfigurable Optical Add and Drop Multiplexer) represents a complete platform for the automatized management of optical networks. Although there are initiatives for the implementation of national ROADM equipment, the LMP protocol for such platforms, in the form open source, has not yet been made available. In this direction, the present work brings a contribution for such integration, make available the related protocol, for use with package DRAGON. Tests were performed in the Laboratory LACE with the LMP protocol in package DRAGON. The results experimental had proven the related functionalities of the protocol to the control channel establishment, maintenance and management, beyond the identification the properties of adjacent nodes and isolation of single or multiple failures in the optical domain management link. Such characteristics, are essential for the complete functioning of management GMPLS, which allows the total automation of platforms of optical networks
Ártico, Adriana Felix Roberto. "Implementação do protocolo LMP de gerência de enlace em redes GMPLS ópticas /." São José do Rio Preto : [s.n.], 2011. http://hdl.handle.net/11449/98697.
Повний текст джерелаBanca: Edilson Reis Rodrigues Kato
Banca: Adriano Mauro Cansian
Resumo: O presente trabalho descreve a implementação open-source do Protocolo de Gerência de Enlace denominado LMP (Link Management Protocol), baseado na RFC 4204. Este protocolo faz parte da arquitetura GMPLS (Generalized Multi-Protocol Label Switching), responsável por gerenciar de forma automatizada as redes ópticas. O protocolo LMP, quando utilizado em conjunto com o pacote open-source DRAGON, disponibiliza ferramentas de gerenciamento distribuído apropriadas para uso em ambientes GMPLS. Neste contexto, ferramentas de roteamento distribuído, estabelecimento rápido de conexões por meio de sinalização e descoberta de serviços podem ser utilizadas. A integração do protocolo LMP open source, no contexto do pacote DRAGON, em equipamentos denominados ROADM (Multiplexador de Inserção/Remoção Óptico Reconfigurável) representa uma plataforma completa para o gerenciamento automatizado de redes ópticas. Embora existam iniciativas de implementação de equipamentos ROADM nacionais, o protocolo LMP para tais plataformas, na forma open source, ainda não foi disponibilizado. Neste sentido, o presente trabalho traz uma contribuição para tal integração, disponibilizando o referido protocolo, para uso com o pacote DRAGON. Foram realizados testes no Laboratório LACE com o protocolo LMP inserido no pacote DRAGON. Os resultados experimentais obtidos comprovaram as funcionalidades do protocolo relacionadas ao estabelecimento, manutenção e gerenciamento do canal de controle, além da identificação das propriedades dos nós adjacentes e isolação de falhas simples ou múltiplas no domínio óptico do gerenciamento do enlace. Tais características, são essenciais para o funcionamento completo do gerenciamento GMPLS, o qual permite a automação total de plataformas de redes ópticas
Abstract: This dissertation describes the open-source implementation of the Link Management Protocol denominated LMP (Link Management Protocol), based on RFC 4204. This protocol is part of the GMPLS (Generalized Multi-Protocol Label Switching) architecture responsible for managing automatable fiber-optic netwoks. The Protocol LMP, when used together with the package open-source DRAGON, provides tools of management distributed appropriate for use in environments GMPLS. In this context, tools of distributed routing, fast connection establishment via signalling and service discovery can be used. The integration of open source protocol LMP, in the context of package DRAGON, in called equipment ROADM (Reconfigurable Optical Add and Drop Multiplexer) represents a complete platform for the automatized management of optical networks. Although there are initiatives for the implementation of national ROADM equipment, the LMP protocol for such platforms, in the form open source, has not yet been made available. In this direction, the present work brings a contribution for such integration, make available the related protocol, for use with package DRAGON. Tests were performed in the Laboratory LACE with the LMP protocol in package DRAGON. The results experimental had proven the related functionalities of the protocol to the control channel establishment, maintenance and management, beyond the identification the properties of adjacent nodes and isolation of single or multiple failures in the optical domain management link. Such characteristics, are essential for the complete functioning of management GMPLS, which allows the total automation of platforms of optical networks
Mestre
Compagnon, Nathalie. "Utilisation de l'acide tout-transrétinoi͏̈que dans les leucémies aigües promyélocytaires : expérience montpelliéraine des protocoles LAP 91 et LAP 93." Montpellier 1, 1995. http://www.theses.fr/1995MON11070.
Повний текст джерелаNgugi, Freelance Bwalya and Lawrence. "PERFORMANCE EVALUATION OF MPLS/GMPLS CONTROL PLANE SIGNALING PROTOCOLS." Thesis, Blekinge Tekniska Högskola, Sektionen för datavetenskap och kommunikation, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-4012.
Повний текст джерелаCardoso, Silvia Amalia Canova. "Qualidade de vida nos protocolos clínicos do Hospital de Reabilitação de Anomalias Craniofaciais." Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/61/61132/tde-16022009-122327/.
Повний текст джерелаObjective: Verifying the existence of items of Quality of Life in the clinical protocols of the Hospital of Rehabilitation of Anomalies Craniofacials. Model: Observational study, cross and descriptive in patients handbooks, about domains of quality of life (1) social conviviality, (2) relationship among people, (3) education, (4) school performance, (5) le isure, (6) satisfaction whit the result of treatment and (7) complaints, in the pediatrics areas, nursing, social work, nutrition, genetics, plastic surgery, ear doctor, speech pathologist, psychology, phisiotherapy, childs dentist and orthodontists. Setting: HRAC/USP, Bauru. Participants: Clinical protocols and 314 patients handbooks whose ages are between 6 and 12 years old, with cleft lip and cleft palate operated. Results: None of the clinical areas contemplated the 7 domains of Quality of life in their clinical protocols. The collection and the registration of those information occurred in 50% of the sample only for the area of social work. The area of speech pathologist is where more investigates are notified and it registers those aspects in evolution sheet of the handbook. Conclusions: The analysis showed that regarding 12 investigated areas, 42% (5) areas contemplate domains related to the evaluation of quality of life in the structure of the clinical protocols and although that there is inconsis tency in the collection and registration of those data, the occurrence of domains of Quality of Life in clinical practice is observed in 66% of the areas that make it as spontaneous way in the evolution sheet.
Gopal, Rachna. "Development of a communication assessment protocol for young children with cleft lip and/or palate (CL/P) in Mauritius." Thesis, University of Pretoria, 2009. http://hdl.handle.net/2263/28561.
Повний текст джерелаThesis (DPhil)--University of Pretoria, 2010.
Speech-Language Pathology and Audiology
Unrestricted
Paes, Thaís Rebeca. "Londrina ADL protocol (LAP) : reprodutibilidade, validade e valores de referência em adultos fisicamente independentes com 50 anos ou mais." Universidade Estadual de Londrina. Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências da Reabilitação, 2016. http://www.bibliotecadigital.uel.br/document/?code=vtls000206287.
Повний текст джерелаBackground: It is important to assess activities of daily living (ADL) in older adults, and there is no availability of an objective and standardized protocol to assess this outcome. Aims: To verify the reproducibility of a new protocol, the Londrina ADL Protocol (LAP), and to investigate its validity in physically independent adults aged 50 and older; to establish an equation to predict reference values of the LAP for this population. Methods: Ninety three physically independent adults aged 50 and older had their capacity to perform ADL evaluated by registering the time spent to conclude the LAP (a protocol composed by five different activities that simulate ADL which involve upper and lower limbs carried out on a circuit). The protocol was performed twice, in order to verify its reproducibility. The six-minute walk test (6MWT), that assesses functional exercise capacity, was used as a validation criterion. A model of multiple linear regression was applied, including anthropometric and demographic variables (gender, age, weight, heigh) that correlated with the LAP, to establish an equation to predict the reference values of the protocol. Other assessments: pulmonary function (spirometry), number of spets (pedometer), functional physical capacity (30-second chair stand test, 6-minute pegboard and ring test, timed up and go, and one-leg balance test), independence in daily life and mental status. Results: In general, the LAP was reproducible (ICC: 0.91). The difference between the first and second LAP was 5.3%. The LAP was valid to assess ADL in the studied subjects, presenting a moderate correlation with the 6MWT (r=-0.46). The time spent to perform the LAP correlated with age (r=0.45), but neither with weight (r=-0.17) nor with height (r=-0.17). A model of stepwise multiple regression including gender and age showed that age was the only determinant factor to the LAP, explaining 21% (P<0.0001) of its variability. The derived reference equation was: LAPpred(sec)=135.618+(3.102*age [years]). Conclusion: In general, the LAP was reproducible and valid in physically independent adults aged 50 and older. A reference equation for the LAP was established, including as independent variable only age (r2=0.21), allowing a better interpretation of the results when the protocol will be used in the clinical practice.
Groh, Ellen Louise. "Severe, Chronic Auditory Comprehension Deficits: An Intensive Treatment and Cueing Protocol." Miami University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=miami1336482231.
Повний текст джерелаCANAPLE, BONNAY SANDRINE. "Lymphomes cerebraux primitifs : aspects cliniques, neuroradiologiques, therapeutiques et pronostiques ; resultats du protocole lcp 88 ; a propos de 48 patients." Amiens, 1993. http://www.theses.fr/1993AMIEM026.
Повний текст джерелаLauris, Rita de Cassia Moura Carvalho. "Avaliação da estética facial de pacientes com fissura transforame incisivo bilateral, submetidos ao protocolo de cirurgias do HRAC-USP." Universidade de São Paulo, 2005. http://www.teses.usp.br/teses/disponiveis/61/61132/tde-17082006-101415/.
Повний текст джерелаObjective: to evaluate, by means of photographs of profile and a specific questionnaire, the facial esthetics of individuals with complete bilateral cleft lip and palate (CBCLP) operated according to the protocol of HRAC-USP. Design: cross-sectional study with analysis of the photographs, by assignment of scores to the patients and statistical comparison. Setting: HRAC-USP. Participants: sample: 30 white patients with CBCLP, being 24 males and 6 females, aged 5 years 8 months to 10 years 4 months. Examines: 5 orthodontists of HRAC-USP (OHRAC), 5 orthodontists not treating patients with clefts (ONC), 5 plastic surgeons of HRAC-USP (PSHRAC), 5 plastic surgeons not treating patients with clefts (PSNC), and 5 lay graduated examiners (L). Variables: classification of facial pleasantness in a scale from 1 to 9, structures recognized as responsible for the worst classification. Results: the OHRAC group assigned a median of 7 (esthetically pleasant appearance) and the PSHRAC assigned 5 (esthetically acceptable). Group L assigned 4 (esthetically acceptable). Groups ONC and PSNC assigned 3 (esthetically unpleasant). There was a significant difference between all categories, except for ONC and PSNC. The structures associated to the esthetically unpleasant classification were the nose, middle third of the face and upper lip. Conclusions: the facial esthetics of the sample was classified as pleasant (OHRAC group), acceptable (PSHRAC and L groups) and unpleasant (ONC and PSNC groups). here was a significant difference between groups, except for the ONC and PSNC. The structures associated to the worst scores were the nose, middle third of the face and upper lip.
Israel, Dave, Ron Parise, Keith Hogie, and Ed Criscuolo. "SPACE COMMUNICATION DEMONSTRATION USING INTERNET TECHNOLOGY." International Foundation for Telemetering, 2002. http://hdl.handle.net/10150/607486.
Повний текст джерелаThis paper presents work being done at NASA/GSFC by the Operating Missions as Nodes on the Internet (OMNI) project to demonstrate the application of Internet communication technologies to space communication. The goal is to provide global addressability and standard network protocols and applications for future space missions. It describes the communication architecture and operations concepts that will be deployed and tested on a Space Shuttle flight in July 2002. This is a NASA Hitchhiker mission called Communication and Navigation Demonstration On Shuttle (CANDOS). The mission will be using a small programmable transceiver mounted in the Shuttle bay that can communicate through NASA’s ground tracking stations as well as NASA’s space relay satellite system. The transceiver includes a processor running the Linux operating system and a standard synchronous serial interface that supports the High-level Data Link Control (HDLC) framing protocol. One of the main goals will be to test the operation of the Mobile IP protocol (RFC 2002) for automatic routing of data as the Shuttle passes from one contact to another. Other protocols to be utilized onboard CANDOS include secure login (SSH), UDP-based reliable file transfer (MDP), and blind commanding using UDP. The paper describes how each of these standard protocols available in the Linux operating system can be used to support communication with a space vehicle. It will discuss how each protocol is suited to support the range of special communication needs of space missions.
Leirião, Véra Helena Valente. "Estudo comparativo em crianças com e sem fissura labiopalatina através do protocolo de triagem do desenvolvimento da linguagem até três anos de idade." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/61/61131/tde-25092014-184323/.
Повний текст джерелаObjective: The goals of the present work are: to generale a protocol screening to evaluate the development of language in Brazilian children; to analise differences existing in language skills in children with/without cleft lip/palate, and to verify differences existing in the profile of language development between children with clefting, with/ without median otitis. Model: Prospective study based in randomized sampling Setting: Speech Pathology Section, Public Health Ambulatory, HRAC-USP Participants: 163 children composed this sample, where 102 presented cleft lip/palate (52 with otitis media and 50 without) and 61 normal children. The age ranged between 22 to 24 months and from 34 to 36 months, according the routine agenda. Intervention: The Protocol was applied to all children having less than 36 months. It includes the following scales: REEL-2, ELM and LDS, as well as the speech language evaluation, concerning early identification of children at risk for developmental language delay. Results: Through the Protocol screening we showed that there was significant standard deviation in receptive developmental language delay detected through the REEL-2 Scale, mainly for children with CL/P at age 36 months. The ELM and LDS scales showed significant standard deviation for expressive language delay, mainly in children without clefting at age 36 months. These data were confirmed through speech-language evaluation. Conclusions: The studied Protocol was efficient in all circumstances, mainly when we take into account the differences existing between children with cleft lip/palate with and without otitis media, and when we also consider the groups with and without CL/P. We suggest that this Protocol should be established as a routine procedure in the evaluation of at risk patients, no matter where they are.
Pereira, Rui Manuel Rodrigues. "Avaliação do crescimento facial em dois protocolos para cirurgias primárias em pacientes com fissura labiopalatina unilateral: ensaio clínico randomizado." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-20062017-102804/.
Повний текст джерелаBackground and Objective: An adequate growth of dentofacial structures is one of the most important goals of unilateral cleft lip and palate(UCLP) treatment and has a definitive role in getting good aesthetic and dental occlusion outcomes. To the present date several papers highlight the need of evidence-based studies to find surgical protocols that can improve facial growth and speech results aiming to reduce the burden of care of overall treatment. This study has evaluated and compared the dental arch relationship at 5 years of age after two treatment protocols, one submitted to one stage cleft palate repair (CPR) and the other to a two stage CPR with delayed hard palate closure (DHPC). The author\'s hypothesis is that the DCHP protocol provides a better dentofacial growth. Methods: A randomized clinical trial was held to evaluate the maxilo-mandibular relations in two groups of initially 32 patients each, randomly chosen. The GI group (n=32) was submitted to veloplasty between 6-9 months of age and a DCHP palatoplasty between three and four years of of age. The immediate complications were evaluated, oronasal fistulas, and cleft severity and their relationships to the surgical protocols. The dental arch relationships were assessed by a blind panel of three independent orthodontists using the FYOI index. The Kappa statistics were calculated to ensure the level of confidence. The results were statistically tested by t and Q-squared tests. Results: The GI group consisted of 32 patients while the GC group consisted of 30 patients. The oronasal fistulas incidence rate was 9.4% (GI) and 6.7% (GC), and there was no association to surgical techniques. Study models of 62 patients at the average age of 55.5 months were available for assessment. Good to very good levels of intra- and interrater reliability were obtained (0.67-0.87 and 0.76-0.90). The mean index scores varied between 2.04 (GI) and 2.76 (GC) with a statistically significant difference (p=0.007). When all evaluations were distributed between indexes good (1 and 2), regular (3) and bad (4 and 5); a statistically significant difference was observed between the GI and GC groups (p = 0.006),. The GI Group presented a 74% rate of good scores, while the GC Group rated 52% in good scores. When comparing the distributions by median, a difference (p = 0.024) was found between scores 1 of the GI (31.2%) and GC (3.3%) groups. The correlation between the cleft severity and the dental arch relationships assessed by the FYOI was not evidenced by the Spearman method. Conclusions: The ECR results provide statistical evidence that the DCHP protocol delivers better outcomes related to dentofacial growth. There was no correlation found between the cleft severity, palatal width and the results related to maxilar growth. The prevalence of oronasal fistules is similar in both surgical protocols
Neves, Lucimara Teixeira das. "Triagem de mutação no éxon 3 do gene IRF6 em indivíduos com fissura labiopalatina e agenesia dentária: padronização de protocolo para seqüenciamento de DNA genômico a partir de saliva." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/25/25142/tde-25032010-091704/.
Повний текст джерелаCleft lip and palate and tooth agenesis are considered changes in embryonic development. These phenotypes occur as a result of the interaction of genetic and environmental factors, suggesting a multifactorial inheritance pattern. Among the candidate genes for these phenotypes IRF6 appears as one of the most important. Direct sequencing, among other techniques, can be used to perform such genetic studies. The aim of this study was to standardize a protocol for direct sequencing of genomic DNA extracted from whole saliva to allow further search of mutations or polymorphisms in exon 3 of IRF6 gene in individuals with nonsyndromic cleft lip and palate and tooth agenesis. Volunteers were 120 subjects divided into four groups: Group 1 - 30 individuals with tooth agenesis and cleft, Group 2 - 30 individuals with cleft only, Group 3 - 30 individuals with tooth agenesis only, and Group 4 - Control. For the analysis of the exon 3 of IRF6 gene, saliva was collected to test three protocols for the extraction of genomic DNA. Additionally, during the protocol standardization for direct sequencing, different methodologies for the other three steps of sample preparation were evaluated: purification of PCR product, optimization of the use of BigDye® v3.1 Terminator, and purification of the sequencing product. The samples were sequenced on ABI 3130XL Genetic Analyzer, and the results were analyzed using specific softwares. Heterozygous and homozygous variations in the sequences of the exon 3 of IRF6 gene of each individual were searched in the electropherograms. The results showed that the protocol for DNA extraction from saliva using InstageneTM Matrix associated with proteinase K and 1% sodium dodecyl sulfate showed the best results in the quantity and quality of the extracted DNA. As far as the purification of the PCR product, the method of choice was the purification in specific columns. BigDye® v3.1 was used with success in a volume 2 L per reaction, and the purification of the sequencing product with X-Terminator showed the best results. For the mutation screening, only one individual of the control group presented sequence variation of the heterozygous type. It was concluded that it is possible to successfully perform, on the ABI 3130XL platform, the direct sequencing of genomic DNA extracted from whole saliva using the protocols standardized in this work. It was also concluded that in the group analyzed, no association between the exon 3 of IRF6 gene and the phenotypes of nonsyndromic cleft lip and palate and tooth agenesis was found.
Bernardi, Caren Luciane. "Parâmetros comportamentais e bioquímicos gliais e inflamatórios em pacientes com lesão da medula espinhal submetidos à dança, e em ratos Wistar submetidos aos protocolos de exercício voluntário e forçado." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/143581.
Повний текст джерелаThe main aim of this Thesis was to evaluate the biochemical glial, inflammatory and behavioral parameters, in patient with spinal cord injury (SCI) submitted to a protocol of dance, and in rats submitted to voluntary and forced exercise. Four experiments were made. In the 1st, the rats were submitted to 4 weeks of moderate exercise on treadmill (20 min per day). In the 2nd, the animals were submitted to 4 weeks of voluntary exercise on wheel running (12 hours per day). In the 3rd experiment, the rats were exposed to treadmill during 2 weeks (20 min per day) and, after the last session, they received intraperitoneal injection of LPS. In this last experiment, the memory and learning were investigated. At the finish of the exercise period, or after the LPS injection, the biochemical analysis of the hippocampus was realized. The 4th experiment was realized with individuals with spinal cord injury that were submitted to 4 weeks of dance practice. Behavioral and serological analyses were performed. Data show that treadmill running increased glutamine synthetase (GS) activity and decreased hippocampal glial fibrillary acidic protein (GFAP) and nitric oxide (NO) , as well as increased corticosterone level, that can mediate the effects of the exercise on astrocytes. The voluntary exercise increased GS and BDNF. The LPS administration increased hippocampal TNF-α level in rats concomitantly with the increase in the S100B levels in cerebrospinal fluid. The individuals with spinal cord injury submitted to dance showed a significant improve in the scores of Functional Independency Measure, Barthel Index, Berg Scale and Ansiety and Depression Hospitalar Scale, and a increase in the serologic levels of BDNF. The dance had no effect on glial, metabolic and inflammatory parameters. These results suggest that different types of exercise exert different effects on hippocampal astrocytes, which may interfere with the appointment of one or the other depending on the objective to be achieved. The treadmill exercise can be a good strategy in the prevention of neuroinflammatory diseases, and dance can be an effective therapeutic intervention for rehabilitation of individuals with SCI as it helps to improve physical and psychological conditions in this population. Taken together, the present data highlight the importance of physical exercise for neural functions, and the relevance of studying astrocytes to understand the mechanisms involved in the effect of exercise on CNS.
Bhati, Bhawani Shanker. "Design of Privacy Protection Schemes for Mobile Adhoc Networks using Rough Set Theory." Thesis, 2018. https://etd.iisc.ac.in/handle/2005/5264.
Повний текст джерела"Análisis y Modelado del MPLS(Multi-Protocol Label Switching) para el manejo de tráfico en redes de comunicaciones." Tesis, Universidad de las Américas Puebla, 2004. http://catarina.udlap.mx/u_dl_a/tales/documentos/lep/martinez_s_jc/.
Повний текст джерелаSwiegers, Dorethea. "Development of a perceptual speech assessment protocol for Zulu-speaking children with cleft palate." Diss., 2010. http://hdl.handle.net/2263/27045.
Повний текст джерелаDissertation (MCommunication Pathology)--University of Pretoria, 2010.
Speech-Language Pathology and Audiology
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Mohd, Ibrahim Hasherah. "Nasality in the Malay language: development of an assessment protocol for Malay speaking children with cleft lip and/or palate." 2009. http://repository.unimelb.edu.au/10187/5658.
Повний текст джерелаIn the first study, three stimuli were developed for the assessment of nasality based on both the proportion of nasal phonemes in typical conversation samples in Malay and guidelines from the current international literature. The phonetic content of the stimuli were comparable to similar passages used in English and comprised of an Oral Passage, a Nasal Passage and a Set of Sentences.
In the second study, the stimuli constructed were tested in a large number of typically developing (non-cleft) Malay speaking children using both instrumental and perceptual methods of assessment. The results of this study provide the first set of normative data of nasalance scores for the three newly developed stimuli. The mean nasalance score for the Oral Passage was 13.86% (SD = 5.11, 95% CI = 13.04–14.68), 60.28% (SD = 6.99, 95% CI = 59.15–61.41) for the Nasal Passage, and 27.72% (SD = 4.74, 95% CI = 26.96–28.49) for the Set of Sentences. These scores were significantly different from each other suggesting that they can be used to detect the different types of resonance disorder in speech (e.g. hypernasality and/or hyponasality).
In the third study, the stimuli were validated in a sample of Malay speaking children with cleft of the lip and/or palate and compared with a control population. Nasality was measured using perceptual evaluation and nasometry. The results suggested that the Oral Passage and Set of Sentences developed in Malay were valid measures for detecting hypernasality for both perceptual evaluation of nasality, and for nasometry. Due to the small number of participants that were hyponasal, the validity of the Nasal Passage could not be determined.
For nasometry to be clinically relevant threshold values that indicate abnormal nasality are required. The threshold values for each of the stimuli were first ascertained after obtaining typical nasality levels from a group of healthy Malay speaking children and then tested in a sample of cleft and non-cleft Malay speaking children. In contrast to the nasalance cutoffs obtained from typical Malay speaking children, the cutoffs obtained from the cleft children yielded better outcomes for detecting resonance disorders. The cutoffs were: ≥ 22% for the Oral Passage (sensitivity = 0.91, specificity = 0.93, overall efficiency = 0.92), ≥ 30% for the Set of Sentences (sensitivity = 0.96, specificity = 0.85, overall efficiency = 0.88) and ≤ 39 on the Nasal Passage (sensitivity = 1.00, specificity = 0.99, overall efficiency = 0.99).
Finally, the fourth study explored the application of recently developed techniques for assessing nasality using spectral voice analysis and compared these results with nasometry using a sub-sample of Malay speaking children from the third study. The participants were children with cleft lip and/or palate with perceived hypernasality and a group of healthy controls perceived to have normal resonance. The potential of assessing nasality using vowels, which ideally can be an easier option to administer clinically and have minimal impact on language and literacy skills, were investigated.
The findings showed that only the one-third-octave analysis method could be successfully used to detect hypernasality in the cleft population compared to the VLHR method. Using the one-third-octave analysis, the spectral characteristics of nasalised vowel /i/ taken from /pit/ and /tip/ showed an increase in amplitude in F1, between F1 and F2 regions. The amplitude of the formants at F3 region was lower in the cleft group but did not differ from the control group as reported in previous studies. Although, the one-third-octave analysis has some potential in detecting hypernasality, the accuracy of the analysis compared to perceptual ratings of nasality was only moderate. Compared to nasometry, the diagnostic value of the one-third-octave analysis in detecting hypernasality was lower.
The overall findings suggest that, except for the Nasal Passage, the Oral Passage and the Set of Sentences developed in Malay using this systematic approach were culturally appropriate and valid for the assessment of nasality. Furthermore, by comparing two instrumental methods (nasometry and spectral analysis) with perceptual evaluation in a large number of cleft and typically developing children, the present thesis was able to demonstrate the clinical benefits of two recently proposed methods of spectral voice analyses and compare them to existing methods. Compared to spectral analysis, nasometry remains a superior method for assessing nasality. Threshold values that indicate abnormal nasality levels for the newly developed stimuli in Malay have been recommended.
Nemtur, Aamani. "Failure recovery techniques over an MPLS network using OPNET." Thesis, 2014. http://hdl.handle.net/1805/6281.
Повний текст джерелаMulti-Protocol Label Switching (MPLS) is an emerging technology which is the initial step for the forthcoming generation of communication. It uses Labels in order to identify the packets unlike the conventional IP Routing Mechanism which uses the routing table at each router to route the packet. MPLS uses the techniques of FRR with the help of RSVP/CR-LDP to overcome the link and/or node failures in the network. On the other hand there are certain limitations/drawbacks of using the above mechanisms for Failure Detection and Recovery which are multiple protocols such as RSVP/CR-LDP over OSPF/IS-IS and complex algorithms to generate backup paths since each router works individually in order to create a backup tunnel. So to overcome the listed limitations, this paper discusses a new technique for MPLS Networks which is Source Routing \cite{48}. Source Routing is the technique in which the source plays the role of directing the packet to the destination and no other router plays the role of routing the packet in the network. Using the OPNET Modeler 17.5 tool for implementing source routing when there is a network failure is performed and the results are compared by implementing RSVP/CR-LDP over the same failed network. The comparative results show that the network performance is best in the case of Source Routing implementation as compared to the RSVP and CR-LDP signaling over the MPLS Networks.