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1

Courvoisier, Aurélien, Antonio Cebrian, Julien Simon, Pascal Désauté, Benjamin Aubert, Célia Amabile, and Lucie Thiébaut. "Virtual Scoliosis Surgery Using a 3D-Printed Model Based on Biplanar Radiographs." Bioengineering 9, no. 9 (September 14, 2022): 469. http://dx.doi.org/10.3390/bioengineering9090469.

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The aim of this paper is to describe a protocol that simulates the spinal surgery undergone by adolescents with idiopathic scoliosis (AIS) by using a 3D-printed spine model. Patients with AIS underwent pre- and postoperative bi-planar low-dose X-rays from which a numerical 3D model of their spine was generated. The preoperative numerical spine model was subsequently 3D printed to virtually reproduce the spine surgery. Special consideration was given to the printing materials for the 3D-printed elements in order to reflect the radiopaque and mechanical properties of typical bones most accurately. Two patients with AIS were recruited and operated. During the virtual surgery, both pre- and postoperative images of the 3D-printed spine model were acquired. The proposed 3D-printing workflow used to create a realistic 3D-printed spine suitable for virtual surgery appears to be feasible and reliable. This method could be used for virtual-reality scoliosis surgery training incorporating 3D-printed models, and to test surgical instruments and implants.
2

Gajny, Laurent, Shahin Ebrahimi, Claudio Vergari, Elsa Angelini, and Wafa Skalli. "Quasi-automatic 3D reconstruction of the full spine from low-dose biplanar X-rays based on statistical inferences and image analysis." European Spine Journal 28, no. 4 (October 31, 2018): 658–64. http://dx.doi.org/10.1007/s00586-018-5807-6.

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3

Andellini, Martina, Francesco Faggiano, Roxana di Mauro, Pietro Derrico, and Matteo Ritrovato. "OP45 HTA Of A Pediatric Biplanar Low-Dose X-Ray Imaging System." International Journal of Technology Assessment in Health Care 34, S1 (2018): 17–18. http://dx.doi.org/10.1017/s0266462318000983.

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Introduction:Patients with adolescent idiopathic scoliosis frequently receive X-ray imaging at diagnosis and subsequent follow monitoring. To achieve the ALARA concept of radiation dose, a biplanar low-dose X-ray system (BLDS) has been proposed. The aim of the study is to gather evidence on safety, accuracy and overall effectiveness of a BLDS compared with CT scanning, in a pediatric population, in order to support the final decision on possible acquisition of such innovative diagnostic system.Methods:The new method Decision-oriented HTA (DoHTA) was applied to carefully assess the diagnostic technology. It was developed starting from the EUnetHTA Core Model® integrated with the analytic hierarchy process in order to identify all the relevant assessment aspects of the technology involved, identified from scientific literature, experts’ judgments and specific context analysis of Bambino Gesù Children's Hospital. A weight was associated to each assessment element and the alternatives’ ranking was defined.Results:This innovative system provides orthopedic images in standing or sitting position, being able to examine the spine and lower limbs under normal weight-bearing conditions. This system is recommended for particular clinical indications as scoliosis and other congenital deformities of the spine. It is able to acquire simultaneous posteroanterior and lateral images in a single scan without vertical distortion and with lower radiation exposure than CT scanning. 2D images acquired can be combined to obtain a 3D reconstruction scanning based on a semi-automated statistical model.Conclusions:The major advantages of BLDS are the relatively low dose of radiation and the possibility of obtaining a 3D reconstruction of the bones. Our preliminary results show that data on the clinical effectiveness are limited but the technical advancements of BLDS appear promising in terms of patient management and patient health outcomes associated with its use.
4

Goodbody, Christine, Paz Kedem, Michaela Thompson, Huong T. Do, Douglas N. Mintz, Roger F. Widmann, and Emily R. Dodwell. "Reliability and Reproducibility of Subject Positioning with EOS Low-Dose Biplanar X-ray." HSS Journal ® 13, no. 3 (March 1, 2017): 263–66. http://dx.doi.org/10.1007/s11420-017-9548-6.

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5

Hurry, Jennifer K., Alan J. Spurway, Elise K. Laende, Saad Rehan, Janie L. Astephen Wilson, Michael J. Dunbar, and Ron El-Hawary. "A low-dose biplanar X-ray imager has RSA level precision in total knee arthroplasty." Acta Orthopaedica 94 (November 30, 2023): 555–59. http://dx.doi.org/10.2340/17453674.2023.19669.

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Background and purpose: The low radiation biplanar X-ray imager (EOS imaging, Paris, France) scans patients in a weight-bearing position, provides calibrated images, and limits radiation, an asset for serial radiostereometric analysis (RSA) studies. RSA in vivo precision values have not been published for this type of imaging system, thus the goal of this study was to assess the precision of RSA in vivo utilizing a low radiation biplanar imager.Patients and methods: At a mean of 5 years post-surgery (range 1.4–7.5 years), 15 total knee arthroplasty (TKA) participants (mean age 67 years at the time of imaging, 12 female, 3 male) with RSA markers implanted during index surgery were scanned twice at the same visit in the EOS imager. Precision of marker-based analysis was calculated by comparing the position of the implant relative to the underlying bone between the 2 examinations.Results: The 95% limit of precision was 0.11, 0.04, and 0.15 mm along the x, y, and z axes, respectively and 0.15°, 0.20°, and 0.14° around the same axes.Conclusion: This precision study has shown an in vivo RSA precision of ≤ 0.15 mm and ≤ 0.20°, well within published uniplanar values for conventional arthroplasty RSA, with the added benefit of weight-bearing imaging, a lower radiation dose, and without the need for a reference object during the scan.
6

Berg, Britt-Isabelle, Aurélien Laville, Delphine S. Courvoisier, Philippe Rouch, and Thomas Schouman. "Experiences with a new biplanar low-dose X-ray device for imaging the facial skeleton: A feasibility study." PLOS ONE 15, no. 7 (July 2, 2020): e0235032. http://dx.doi.org/10.1371/journal.pone.0235032.

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7

Ben-Sira, Liat, Shelly I. Shiran, Li-tal Pratt, Ronit Precel, Dror Ovadia, Shlomi Constantini, and Jonathan Roth. "Use of EOS Low-Dose Biplanar X-Ray for Shunt Series in Children with Hydrocephalus: A Preliminary Study." World Neurosurgery 116 (August 2018): e273-e277. http://dx.doi.org/10.1016/j.wneu.2018.04.187.

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8

Gheno, Ramon, Eric Nectoux, Bernard Herbaux, Matteo Baldisserotto, Luiz Glock, Anne Cotten, and Nathalie Boutry. "Three-dimensional measurements of the lower extremity in children and adolescents using a low-dose biplanar X-ray device." European Radiology 22, no. 4 (October 20, 2011): 765–71. http://dx.doi.org/10.1007/s00330-011-2308-y.

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9

Hosseinian, S., and H. Arefi. "3D RECONSTRUCTION FROM MULTI-VIEW MEDICAL X-RAY IMAGES – REVIEW AND EVALUATION OF EXISTING METHODS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XL-1-W5 (December 11, 2015): 319–26. http://dx.doi.org/10.5194/isprsarchives-xl-1-w5-319-2015.

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The 3D concept is extremely important in clinical studies of human body. Accurate 3D models of bony structures are currently required in clinical routine for diagnosis, patient follow-up, surgical planning, computer assisted surgery and biomechanical applications. However, 3D conventional medical imaging techniques such as computed tomography (CT) scan and magnetic resonance imaging (MRI) have serious limitations such as using in non-weight-bearing positions, costs and high radiation dose(for CT). Therefore, 3D reconstruction methods from biplanar X-ray images have been taken into consideration as reliable alternative methods in order to achieve accurate 3D models with low dose radiation in weight-bearing positions. Different methods have been offered for 3D reconstruction from X-ray images using photogrammetry which should be assessed. In this paper, after demonstrating the principles of 3D reconstruction from X-ray images, different existing methods of 3D reconstruction of bony structures from radiographs are classified and evaluated with various metrics and their advantages and disadvantages are mentioned. Finally, a comparison has been done on the presented methods with respect to several metrics such as accuracy, reconstruction time and their applications. With regards to the research, each method has several advantages and disadvantages which should be considered for a specific application.
10

Hosseinian, S., and H. Arefi. "PHOTOGRAMMETRY IN 3D MODELLING OF HUMAN BONE STRUCTURES FROM RADIOGRAPHS." ISPRS - International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences XLII-2/W4 (May 10, 2017): 115–21. http://dx.doi.org/10.5194/isprs-archives-xlii-2-w4-115-2017.

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Photogrammetry can have great impact on the success of medical processes for diagnosis, treatment and surgeries. Precise 3D models which can be achieved by photogrammetry improve considerably the results of orthopedic surgeries and processes. Usual 3D imaging techniques, computed tomography (CT) and magnetic resonance imaging (MRI), have some limitations such as being used only in non-weight-bearing positions, costs and high radiation dose(for CT) and limitations of MRI for patients with ferromagnetic implants or objects in their bodies. 3D reconstruction of bony structures from biplanar X-ray images is a reliable and accepted alternative for achieving accurate 3D information with low dose radiation in weight-bearing positions. The information can be obtained from multi-view radiographs by using photogrammetry. The primary step for 3D reconstruction of human bone structure from medical X-ray images is calibration which is done by applying principles of photogrammetry. After the calibration step, 3D reconstruction can be done using efficient methods with different levels of automation. Because of the different nature of X-ray images from optical images, there are distinct challenges in medical applications for calibration step of stereoradiography. In this paper, after demonstrating the general steps and principles of 3D reconstruction from X-ray images, a comparison will be done on calibration methods for 3D reconstruction from radiographs and they are assessed from photogrammetry point of view by considering various metrics such as their camera models, calibration objects, accuracy, availability, patient-friendly and cost.
11

Kerbrat, Adeline, Isabelle Rivals, Pauline Dupuy, Gauthier Dot, Britt-Isabelle Berg, Valérie Attali, and Thomas Schouman. "Biplanar Low-Dose Radiograph Is Suitable for Cephalometric Analysis in Patients Requiring 3D Evaluation of the Whole Skeleton." Journal of Clinical Medicine 10, no. 23 (November 23, 2021): 5477. http://dx.doi.org/10.3390/jcm10235477.

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Background: The biplanar 2D/3D X-ray technology (BPXR) is a 2D/3D imaging system allowing simultaneous stereo-corresponding posteroanterior (PA) and lateral 2D views of the whole body. The aim of our study was to assess the feasibility of cephalometric analysis based on the BPXR lateral skull view to accurately characterize facial morphology. Method: A total of 17 landmarks and 11 angles were placed and/or calculated on lateral BPXR and lateral cephalograms of 13 patients by three investigators. Five methods of angle identification were performed: the direct construction of straight lines on lateral cephalograms (LC-A) and on BPXR (BPXR-A), as well as the calculation of angles based on landmark identification on lateral cephalograms (LA-L) and on BPXR with the PA image (BPXR-LPA) or without (BPXR-L). Intra- and interoperator reliability of landmark identification and angle measurement of each method were calculated. To determine the most reliable method among the BPXR-based methods, their concordance with the reference method, LC-A, was evaluated. Results: Both imaging techniques had excellent intra- and interoperator reliability for landmark identification. On lateral BPXR, BPXR-A presented the best concordance with the reference method and a good intra- and interoperator reliability. Conclusion: BPXR provides a lateral view of the skull suitable for cephalometric analysis with good reliability.
12

Thépaut, Matthias, Sylvain Brochard, Julien Leboucher, Mathieu Lempereur, Eric Stindel, Valentin Tissot, and Bhushan S. Borotikar. "Measuring physiological and pathological femoral anteversion using a biplanar low-dose X-ray system: validity, reliability, and discriminative ability in cerebral palsy." Skeletal Radiology 45, no. 2 (November 27, 2015): 243–50. http://dx.doi.org/10.1007/s00256-015-2298-y.

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13

Assi, A., A. Presedo, A. Baudoin, D. Mitton, I. Ghanem, and W. Skalli. "Specific 3D reconstruction for children lower limbs using a low dose biplanar X-ray system. Reproducibility of clinical parameters for cerebral palsy patients." Computer Methods in Biomechanics and Biomedical Engineering 10, sup1 (January 2007): 27–28. http://dx.doi.org/10.1080/10255840701479065.

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14

Dietrich, Tobias J., Christian W. A. Pfirrmann, Alexander Schwab, Katja Pankalla, and Florian M. Buck. "Comparison of radiation dose, workflow, patient comfort and financial break-even of standard digital radiography and a novel biplanar low-dose X-ray system for upright full-length lower limb and whole spine radiography." Skeletal Radiology 42, no. 7 (March 28, 2013): 959–67. http://dx.doi.org/10.1007/s00256-013-1600-0.

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15

Koutras, Christos, Hamed Shayestehpour, Jesús Pérez, Christian Wong, John Rasmussen, Maxime Tournier, Matthieu Nesme, and Miguel A. Otaduy. "Biomechanical Morphing for Personalized Fitting of Scoliotic Torso Skeleton Models." Frontiers in Bioengineering and Biotechnology 10 (July 19, 2022). http://dx.doi.org/10.3389/fbioe.2022.945461.

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The use of patient-specific biomechanical models offers many opportunities in the treatment of adolescent idiopathic scoliosis, such as the design of personalized braces. The first step in the development of these patient-specific models is to fit the geometry of the torso skeleton to the patient’s anatomy. However, existing methods rely on high-quality imaging data. The exposure to radiation of these methods limits their applicability for regular monitoring of patients. We present a method to fit personalized models of the torso skeleton that takes as input biplanar low-dose radiographs. The method morphs a template to fit annotated points on visible portions of the spine, and it relies on a default biomechanical model of the torso for regularization and robust fitting of hardly visible parts of the torso skeleton, such as the rib cage. The proposed method provides an accurate and robust solution to obtain personalized models of the torso skeleton, which can be adopted as part of regular management of scoliosis patients. We have evaluated the method on ten young patients who participated in our study. We have analyzed and compared clinical metrics on the spine and the full torso skeleton, and we have found that the accuracy of the method is at least comparable to other methods that require more demanding imaging methods, while it offers superior robustness to artifacts such as interpenetration of ribs. Normal-dose X-rays were available for one of the patients, and for the other nine we acquired low-dose X-rays, allowing us to validate that the accuracy of the method persisted under less invasive imaging modalities.
16

Kümmerlin, Jana, Hannah Katharina Fabro, Peter Heide Pedersen, Kenneth Krogh Jensen, Dennis Pedersen, and Michael Skipper Andersen. "Measuring Knee Joint Laxity in Three Degrees-of-Freedom In Vivo Using a Robotics- and Image-Based Technology." Journal of Biomechanical Engineering 144, no. 8 (March 4, 2022). http://dx.doi.org/10.1115/1.4053792.

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Abstract Accurate and reliable information about three-dimensional (3D) knee joint laxity can prevent misdiagnosis and avoid incorrect treatments. Nevertheless, knee laxity assessments presented in the literature suffer from significant drawbacks such as soft tissue artifacts, restricting the knee within the measurement, and the absence of quantitative knee ligament property information. In this study, we demonstrated the applicability of a novel methodology for measuring 3D knee laxity, combining robotics- and image-based technology. As such technology has never been applied to healthy living subjects, the aims of this study were to develop novel technology to measure 3D knee laxity in vivo and to provide proof-of-concept 3D knee laxity measurements. To measure tibiofemoral movements, four healthy subjects were placed on a custom-built arthrometer located inside a low dose biplanar X-ray system with an approximately 60 deg knee flexion angle. Anteroposterior and mediolateral translation as well as internal and external rotation loads were subsequently applied to the unconstrained leg, which was placed inside a pneumatic cast boot. Bone contours were segmented in the obtained X-rays, to which subject-specific bone geometries from magnetic resonance imaging (MRI) scans were registered. Afterward, tibiofemoral poses were computed. Measurements of primary and secondary laxity revealed considerable interpersonal differences. The method differs from those available by the ability to accurately track secondary laxity of the unrestricted knee and to apply coupled forces in multiple planes. Our methodology can provide reliable information for academic knee ligament research as well as for clinical diagnostics in the future.
17

Mekhael, Elio, Rami El Rachkidi, Renee Maria Saliby, Nabil Nassim, Karl Semaan, Abir Massaad, Mohamad Karam, et al. "Functional assessment using 3D movement analysis can better predict health-related quality of life outcomes in patients with adult spinal deformity: a machine learning approach." Frontiers in Surgery 10 (May 3, 2023). http://dx.doi.org/10.3389/fsurg.2023.1166734.

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IntroductionAdult spinal deformity (ASD) is classically evaluated by health-related quality of life (HRQoL) questionnaires and static radiographic spino-pelvic and global alignment parameters. Recently, 3D movement analysis (3DMA) was used for functional assessment of ASD to objectively quantify patient's independence during daily life activities. The aim of this study was to determine the role of both static and functional assessments in the prediction of HRQoL outcomes using machine learning methods.MethodsASD patients and controls underwent full-body biplanar low-dose x-rays with 3D reconstruction of skeletal segment as well as 3DMA of gait and filled HRQoL questionnaires: SF-36 physical and mental components (PCS&MCS), Oswestry Disability Index (ODI), Beck's Depression Inventory (BDI), and visual analog scale (VAS) for pain. A random forest machine learning (ML) model was used to predict HRQoL outcomes based on three simulations: (1) radiographic, (2) kinematic, (3) both radiographic and kinematic parameters. Accuracy of prediction and RMSE of the model were evaluated using 10-fold cross validation in each simulation and compared between simulations. The model was also used to investigate the possibility of predicting HRQoL outcomes in ASD after treatment.ResultsIn total, 173 primary ASD and 57 controls were enrolled; 30 ASD were followed-up after surgical or medical treatment. The first ML simulation had a median accuracy of 83.4%. The second simulation had a median accuracy of 84.7%. The third simulation had a median accuracy of 87%. Simulations 2 and 3 had comparable accuracies of prediction for all HRQoL outcomes and higher predictions compared to Simulation 1 (i.e., accuracy for PCS = 85 ± 5 vs. 88.4 ± 4 and 89.7% ± 4%, for MCS = 83.7 ± 8.3 vs. 86.3 ± 5.6 and 87.7% ± 6.8% for simulations 1, 2 and 3 resp., p < 0.05). Similar results were reported when the 3 simulations were tested on ASD after treatment.DiscussionThis study showed that kinematic parameters can better predict HRQoL outcomes than stand-alone classical radiographic parameters, not only for physical but also for mental scores. Moreover, 3DMA was shown to be a good predictive of HRQoL outcomes for ASD follow-up after medical or surgical treatment. Thus, the assessment of ASD patients should no longer rely on radiographs alone but on movement analysis as well.
18

Hultenmo, Maria, Anders Nygren, Björn Söderberg, and Håkan Wåhlander. "Dose Evaluation and Proposal of Local Diagnostic Reference Levels for Paediatric Cardiac Catheterizations Performed on a High-Sensitivity Angiographic System Allowing Low-Dose Imaging." Radiation Protection Dosimetry, June 9, 2021. http://dx.doi.org/10.1093/rpd/ncab072.

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Abstract Radiation doses from paediatric cardiac catheterizations were analysed based on procedure type and patient weight, and local diagnostic reference levels (LDRLs) were proposed. The procedures were performed on a Siemens Artis Q.zen biplane system with high-sensitivity detectors allowing low-dose imaging. Good radiological practice, e.g. adapting dose level and frame rate continuously and minimizing the x-ray field with collimators, was routine during procedures. The median total dose-area-product (DAP) value was 58 μGym2 for diagnostic catheterizations, 48 μGym2 for interventional catheterizations and 33 μGym2 for myocardial biopsies. The median DAP per body weight was 4.0 μGym2 kg−1. The median total fluoroscopy time varied from 6.0 min for myocardial biopsies, to 9.7 and 10.5 min, respectively, for diagnostic and interventional catheterizations. The third quartile of the DAP values in each weight group was proposed as LDRL. LDRLs for fluoroscopy time were determined solely based on procedure type, due to the absence of weight dependence.
19

Park, Jun Young, Byung Woo Cho, Hyuck Min Kwon, Kwan Kyu Park, and Woo-Suk Lee. "Knee Extension Is Related to the Posteriorly Deviated Gravity Line to the Pelvis in Young Adults: Radiographic Analysis Using Low-Dose Biplanar X-ray." Yonsei Medical Journal 63 (2022). http://dx.doi.org/10.3349/ymj.2022.0184.

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20

Gennari, A., T. Langlais, S. Litrico, S. Persohn, J. Allain, and W. Skalli. "Biomechanical specimen assessment by low dose biplanar X-ray study of fusion constructions using a posterior lumbar cage with integrated anchors and posterior adjunctive fixators." Computer Methods in Biomechanics and Biomedical Engineering, August 16, 2021, 1–7. http://dx.doi.org/10.1080/10255842.2021.1966625.

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21

Deng, Min, Qianyun Chen, Qiao Deng, Lin Shi, Cherry Cheuk Nam Cheng, Kwong Hang Yeung, Rongli Zhang, et al. "Statistical changes of lung morphology in patients with adolescent idiopathic scoliosis after spinal fusion surgery—a prospective nonrandomized study based on low-dose biplanar X-ray imaging." Quantitative Imaging in Medicine and Surgery, January 2021, 0. http://dx.doi.org/10.21037/qims-21-1147.

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22

Peeters, C. M. M., G. J. F. J. Bos, D. H. R. Kempen, P. C. Jutte, C. Faber, and F. H. Wapstra. "Assessment of spine length in scoliosis patients using EOS imaging: a validity and reliability study." European Spine Journal, October 15, 2022. http://dx.doi.org/10.1007/s00586-022-07326-4.

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Abstract Purpose Knowledge about spinal length and subsequently growth of each individual patient with adolescent idiopathic scoliosis (AIS) helps with accurate timing of both conservative and surgical treatment. Radiographs taken by a biplanar low-dose X-ray device (EOS) have no divergence in the vertical plane and can provide three-dimensional (3D) measurements. Therefore, this study investigated the criterion validity and reliability of EOS spinal length measurements in AIS patients. Methods Prior to routine EOS radiograph, a radiographic calibrated metal beads chain (MBC) was attached on the back of 120 patients with AIS to calibrate the images. Spinal lengths were measured from vertebra to vertebra on EOS anteroposterior (AP), lateral view and on the combined 3D EOS view (EOS 3D). These measurements were compared with MBC length measurements. Secondly, intra- and interobserver reliability of length measurements on EOS-images were determined. Results 50 patients with accurately positioned MBC were included for analysis. The correlations between EOS and MBC were highest for the 3D length measurements. Compared to EOS 3D measurements, the total spinal length was systematically measured 4.3% (mean difference = 1.97 ± 1.12 cm) and 1.9% (mean difference = 0.86 ± 0.63 cm) smaller on individual EOS two-dimensional (2D) AP and lateral view images, respectively. Both intra- and interobserver reliability were excellent for all length measurements on EOS-images. Conclusion The results of this study indicate a good validity and reliability for spinal length measurements on EOS radiographs in AIS patients. EOS 3D length measure method is preferred above spinal length measurements on individual EOS AP or lateral view images.
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Peeters, C. M. M., L. van Houten, D. H. R. Kempen, F. H. Wapstra, P. C. Jutte, I. van den Akker-Scheek, and C. Faber. "Assessment of pedicle size in patients with scoliosis using EOS 2D imaging: a validity and reliability study." European Spine Journal, April 25, 2021. http://dx.doi.org/10.1007/s00586-021-06839-8.

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Abstract Purpose Free-hand pedicle screw insertion methods are widely used for screw insertion during scoliosis surgery. Preoperative knowledge about the pedicle size helps to maximize screw containment and minimize the risk of pedicle breach. Radiographs taken by a biplanar low-dose X-ray device (EOS) have no divergence in the vertical plane. The criterion validity and reliability of preoperative EOS images for pedicle size measurements in patients with idiopathic scoliosis (IS) was investigated in this study. Methods Sixteen patients who underwent surgical treatment for IS were prospectively included. Intra- and extracortical pedicle height and width measurements on EOS images were compared with reconstructed intra-operative 3D images of the isthmus of included pedicles. Secondly, intra- and interobserver reliability of pedicle size measurements on EOS images was determined. Results The total number of analyzed pedicles was 203. The correlation between the EOS and 3D scan measurements was very strong for the intra- and extracortical pedicle height and strong for the intra- and extracortical pedicle width. There are, however, significant, but likely clinically irrelevant differences (mean absolute differences < 0.43 mm) between the two measure methods for all four measurements except for extracortical pedicle height. For pedicles classified as Nash–Moe 0, no significant differences in intra- and extracortical pedicle width were observed. Both intra- and interobserver reliability was excellent for all pedicle size measurements on EOS images. Conclusion The results of this study indicate a good validity and reliability for pedicle size measurements on EOS radiographs. Therefore, EOS radiographs may be used for a preoperative estimation of pedicle size and subsequent screw diameter in patients with IS.
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Shakeri, Mohammadreza, Seyed Mani Mahdavi, Masih Rikhtehgar, Mohammad Soleimani, Hasan Ghandhari, Behnam Jafari, and Seyedehsan Daneshmand. "EOS® is reliable to evaluate spinopelvic parameters: a validation study." BMC Medical Imaging 24, no. 1 (February 6, 2024). http://dx.doi.org/10.1186/s12880-023-01178-0.

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Abstract Background Sagittal and coronal standing radiographs have been the standard imaging for assessing spinal alignment. However, their disadvantages include distortion at the image edges and low interobserver reliability in some parameters. EOS® is a low-dose biplanar digital radiographic imaging system that can avoid distortion by obtaining high-definition images. Methods This study aimed to evaluate spinopelvic parameters in conventional lateral C1S1 upright radiographs and EOS® images and compare them. Patients with non-deformity changes were subjected to routine clinical examinations. Plain AP and lateral X-ray radiographs were obtained along the entire spine length. Patients were also referred for full-length EOS® of the spine. Thoracic Kyphosis (TK), Lumbar Lordosis (LL), Pelvic Tilt (PT), Sacral Slope (SS), Pelvic Incidence (PI), and Sagittal Vertical Axis (SVA) were measured in the two studies by an orthopedic surgeon and a radiologist using PACS software. Also, the orthopedic surgeon evaluated the studies again after two weeks. Intra- and inter-observer reliability was then assessed using the interclass correlation coefficient (ICC). Also, the coefficient of variation was used to assess intra- and inter-observer reliability. Bland-Altman plots were drawn for each parameter. Results The mean age was 48.2 ± 6.6 years. Among the 50 patients, 30 (60%) were female. The mean ICC for TK, LL, PT, SS, PI, and SVA in EOS® images are 0.95, 0.95, 0.92, 0.90, 0.94, and 0.98, respectively, and in C1S1 radiography images, it was 0.92, 0.87, 0.94, 0.88, 0.93, and 0.98, respectively which shows good to excellent results. The coefficient of variation for intraobserver reliability was relatively low (< 18.6%), while it showed higher percentages in evaluating interobserver reliability (< 54.5%). Also, the Bland-Altman plot showed good agreement for each parameter. Conclusion Spinopelvic parameters, e.g., TK, LL, SS, PI, and SS, in EOS® are reliable and comparable to those in conventional lateral upright C1S1 radiographs.

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