Статті в журналах з теми "LKB1/mTOR"
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Xiong, Yan, Ziye Xu, Yizhen Wang, Shihuan Kuang, and Tizhong Shan. "Adipocyte-specific DKO of Lkb1 and mTOR protects mice against HFD-induced obesity, but results in insulin resistance." Journal of Lipid Research 59, no. 6 (April 10, 2018): 974–81. http://dx.doi.org/10.1194/jlr.m081463.
Повний текст джерелаJiang, Wenxiao, Yijun Zhang, Ye Huang, Yunfeng Cheng, and Zhigang Liu. "Effect of Hepatic Kinase B1 (LKB1) on Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells During Senescence." Journal of Biomaterials and Tissue Engineering 10, no. 2 (February 1, 2020): 246–51. http://dx.doi.org/10.1166/jbt.2020.2247.
Повний текст джерелаYilmaz, Emrullah, Lauren Averett Byers, Lixia Diao, Uma Giri, Jayanthi Gudikote, You Hong Fan, Jing Wang, et al. "Use of proteomic analysis of LKB1/AMPK/mTOR pathways to identify IGF-1R pathway upregulation with LKB1 loss or mTOR inhibition in NSCLC: Implications for targeted combinations." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 10612. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.10612.
Повний текст джерелаNishimura, Sadaaki, Masakazu Yashiro, Tomohiro Sera, Yurie Yamamoto, Yukako Kushitani, Atsushi Sugimoto, Shuhei Kushiyama, et al. "Serine threonine kinase 11/liver kinase B1 mutation in sporadic scirrhous-type gastric cancer cells." Carcinogenesis 41, no. 11 (March 31, 2020): 1616–23. http://dx.doi.org/10.1093/carcin/bgaa031.
Повний текст джерелаPaunovic, Verica, Stojan Peric, Irena Vukovic, Marina Stamenkovic, Emina Milosevic, Danijela Stevanovic, Milos Mandic, et al. "Downregulation of LKB1/AMPK Signaling in Blood Mononuclear Cells Is Associated with the Severity of Guillain–Barre Syndrome." Cells 11, no. 18 (September 16, 2022): 2897. http://dx.doi.org/10.3390/cells11182897.
Повний текст джерелаYang, Jing, Chengxian Xu, Joseph Lechner, Haley Walls, and Kai Yang. "LKB1 regulates macrophage metabolism and functional polarization in immunomodulation." Journal of Immunology 210, no. 1_Supplement (May 1, 2023): 168.14. http://dx.doi.org/10.4049/jimmunol.210.supp.168.14.
Повний текст джерелаZhou, Wei, Adam I. Marcus, and Paula M. Vertino. "Dysregulation of mTOR activity through LKB1 inactivation." Chinese Journal of Cancer 32, no. 8 (August 5, 2013): 427–33. http://dx.doi.org/10.5732/cjc.013.10086.
Повний текст джерелаBorkowsky, Sarah, Maximilian Gass, Azadeh Alavizargar, Johannes Hanewinkel, Ina Hallstein, Pavel Nedvetsky, Andreas Heuer, and Michael P. Krahn. "Phosphorylation of LKB1 by PDK1 Inhibits Cell Proliferation and Organ Growth by Decreased Activation of AMPK." Cells 12, no. 5 (March 6, 2023): 812. http://dx.doi.org/10.3390/cells12050812.
Повний текст джерелаRadu, Anca G., Sakina Torch, Florence Fauvelle, Karin Pernet-Gallay, Anthony Lucas, Renaud Blervaque, Véronique Delmas, et al. "LKB1 specifies neural crest cell fates through pyruvate-alanine cycling." Science Advances 5, no. 7 (July 2019): eaau5106. http://dx.doi.org/10.1126/sciadv.aau5106.
Повний текст джерелаLi, Yongqiang, Tao Sun, Shuxin Shen, Lixia Wang, and Jifeng Yan. "LncRNA DYNLRB2-2 inhibits THP-1 macrophage foam cell formation by enhancing autophagy." Biological Chemistry 400, no. 8 (July 26, 2019): 1047–57. http://dx.doi.org/10.1515/hsz-2018-0461.
Повний текст джерелаWang, Yuan, Shan Zhu, Hongtao Liu, Wen Wei, Yi Tu, Chuang Chen, Junlong Song, et al. "Thyroxine Alleviates Energy Failure, Prevents Myocardial Cell Apoptosis, and Protects against Doxorubicin-Induced Cardiac Injury and Cardiac Dysfunction via the LKB1/AMPK/mTOR Axis in Mice." Disease Markers 2019 (December 18, 2019): 1–10. http://dx.doi.org/10.1155/2019/7420196.
Повний текст джерелаAkasaka, Yasuyuki, Shun Hasei, Yukino Ohata, Machi Kanna, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, et al. "Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells." International Journal of Molecular Sciences 24, no. 21 (November 6, 2023): 16011. http://dx.doi.org/10.3390/ijms242116011.
Повний текст джерелаShaw, Reuben J., Nabeel Bardeesy, Brendan D. Manning, Lyle Lopez, Monica Kosmatka, Ronald A. DePinho, and Lewis C. Cantley. "The LKB1 tumor suppressor negatively regulates mTOR signaling." Cancer Cell 6, no. 1 (July 2004): 91–99. http://dx.doi.org/10.1016/j.ccr.2004.06.007.
Повний текст джерелаLee, H. R., J. Kim, S. J. Yoo, J. A. Park, and S. W. Kang. "POS0005 THE EFFECT OF LKB1 INHIBITION IN RA PATHOGENESIS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 204.3–204. http://dx.doi.org/10.1136/annrheumdis-2021-eular.946.
Повний текст джерелаAznar, Nicolas, and Marc Billaud. "Primary Cilia Bend LKB1 and mTOR to Their Will." Developmental Cell 19, no. 6 (December 2010): 792–94. http://dx.doi.org/10.1016/j.devcel.2010.11.016.
Повний текст джерелаZhao, Jimeng, Zhe Ma, Handan Zheng, Yan Huang, Luyi Wu, Huangan Wu, Yin Shi, Huirong Liu, and Yanan Liu. "Effects of Herb-Partitioned Moxibustion on Autophagy and Immune Activity in the Colon Tissue of Rats with Crohn’s Disease." Evidence-Based Complementary and Alternative Medicine 2022 (January 28, 2022): 1–12. http://dx.doi.org/10.1155/2022/3534874.
Повний текст джерелаXu, Ziye, Wenjing You, Fengqin Wang, Yizhen Wang, and Tizhong Shan. "Elucidating the role of Lkb1 and mTOR in adipose tissue." Adipocyte 8, no. 1 (October 20, 2018): 26–30. http://dx.doi.org/10.1080/21623945.2018.1535743.
Повний текст джерелаTreilleux, Isabelle, Monica Arnedos, Claire Cropet, Jean-Marc Ferrero, Sophie Abadie Lacourtoisie, Dominique Spaeth, Christelle Levy, et al. "Predictive markers of everolimus efficacy in hormone receptor positive (HR+) metastatic breast cancer (MBC): Final results of the TAMRAD trial translational study." Journal of Clinical Oncology 31, no. 15_suppl (May 20, 2013): 510. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.510.
Повний текст джерелаHuang, Xu, Stephan Wullschleger, Natalia Shpiro, Victoria A. McGuire, Kei Sakamoto, Yvonne L. Woods, Wendy Mcburnie, Stewart Fleming, and Dario R. Alessi. "Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice." Biochemical Journal 412, no. 2 (May 14, 2008): 211–21. http://dx.doi.org/10.1042/bj20080557.
Повний текст джерелаSun, Gao, Andrei I. Tarasov, James A. McGinty, Paul M. French, Angela McDonald, Isabelle Leclerc та Guy A. Rutter. "LKB1 deletion with the RIP2.Cre transgene modifies pancreatic β-cell morphology and enhances insulin secretion in vivo". American Journal of Physiology-Endocrinology and Metabolism 298, № 6 (червень 2010): E1261—E1273. http://dx.doi.org/10.1152/ajpendo.00100.2010.
Повний текст джерелаBi, Chengfeng, Chunsun Jiang, Xiaoxing Jiang, Xin Huang, Mario R. Fernandez, Javeed Iqbal, Robert E. Lewis, Wing Chung Chan, Timothy McKeithan, and Kai Fu. "The Mir-17∼92 Cluster Activates mTORC1 Signaling in MCL by Targeting Multiple Regulators of the LKB1/AMPK/mTOR Pathway." Blood 120, no. 21 (November 16, 2012): 5118. http://dx.doi.org/10.1182/blood.v120.21.5118.5118.
Повний текст джерелаHan, Dong, Shao-Jun Li, Yan-Ting Zhu, Lu Liu, and Man-Xiang Li. "LKB1/AMPK/mTOR Signaling Pathway in Non-small-cell Lung Cancer." Asian Pacific Journal of Cancer Prevention 14, no. 7 (July 30, 2013): 4033–39. http://dx.doi.org/10.7314/apjcp.2013.14.7.4033.
Повний текст джерелаJiménez-Mora, Eva, Beatriz Gallego, Sergio Díaz-Gago, Marina Lasa, Pablo Baquero, and Antonio Chiloeches. "V600EBRAF Inhibition Induces Cytoprotective Autophagy through AMPK in Thyroid Cancer Cells." International Journal of Molecular Sciences 22, no. 11 (June 3, 2021): 6033. http://dx.doi.org/10.3390/ijms22116033.
Повний текст джерелаXiao, Jia, Rui Guo, Man-Lung Fung, Emily C. Liong, Raymond Chuen Chung Chang, Yick-Pang Ching, and George L. Tipoe. "Garlic-Derived S-Allylmercaptocysteine Ameliorates Nonalcoholic Fatty Liver Disease in a Rat Model through Inhibition of Apoptosis and Enhancing Autophagy." Evidence-Based Complementary and Alternative Medicine 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/642920.
Повний текст джерелаTzatsos, Alexandros, and Konstantin V. Kandror. "Nutrients Suppress Phosphatidylinositol 3-Kinase/Akt Signaling via Raptor-Dependent mTOR-Mediated Insulin Receptor Substrate 1 Phosphorylation." Molecular and Cellular Biology 26, no. 1 (January 1, 2006): 63–76. http://dx.doi.org/10.1128/mcb.26.1.63-76.2006.
Повний текст джерелаShaw, R. J. "LKB1 and AMP-activated protein kinase control of mTOR signalling and growth." Acta Physiologica 196, no. 1 (May 2009): 65–80. http://dx.doi.org/10.1111/j.1748-1716.2009.01972.x.
Повний текст джерелаGreen, Alexa S., Nicolas Chapuis, Thiago Trovati Maciel, Lise Willems, Mireille Lambert, Christophe Arnoult, Olivier Boyer, et al. "The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation." Blood 116, no. 20 (November 18, 2010): 4262–73. http://dx.doi.org/10.1182/blood-2010-02-269837.
Повний текст джерелаMoore, Timothy M., Xavier M. Mortensen, Conrad K. Ashby, Alexander M. Harris, Karson J. Kump, David W. Laird, Aaron J. Adams, Jeremy K. Bray, Ting Chen, and David M. Thomson. "The effect of caffeine on skeletal muscle anabolic signaling and hypertrophy." Applied Physiology, Nutrition, and Metabolism 42, no. 6 (June 2017): 621–29. http://dx.doi.org/10.1139/apnm-2016-0547.
Повний текст джерелаLemoine, Manuela, Enrico Derenzini, Daniela Buglio, L. Jeffrey Medeiros, R. Eric Davis, Jiexin Zhang, Yuan Ji, and Anas Younes. "The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines." Blood 119, no. 17 (April 26, 2012): 4017–25. http://dx.doi.org/10.1182/blood-2011-01-331421.
Повний текст джерелаJung, Taek-Yeol, Jae-Eun Ryu, Mi-Mi Jang, Soh-Yeon Lee, Gyu-Rin Jin, Chan-Woo Kim, Chae-Young Lee, et al. "Naa20, the catalytic subunit of NatB complex, contributes to hepatocellular carcinoma by regulating the LKB1–AMPK–mTOR axis." Experimental & Molecular Medicine 52, no. 11 (November 2020): 1831–44. http://dx.doi.org/10.1038/s12276-020-00525-3.
Повний текст джерелаColombo, Marika, Matteo Demetrio Tripodi, Gabriel Caso, Elisa Perin, Mirko Marabese, Massimo Broggini, and Elisa Caiola. "Abstract 6346: Identification of ERK inhibitor-based combinations targeting LKB1-mutated NSCLC." Cancer Research 82, no. 12_Supplement (June 15, 2022): 6346. http://dx.doi.org/10.1158/1538-7445.am2022-6346.
Повний текст джерелаYang, Cong, Hongyu Ding, Yang Yang, Long Yang, Yun Yang, Meimiao Fang, Jin Ren, Ronggui Hu, Chengcheng Wang, and Wujun Geng. "BAP1 regulates AMPK-mTOR signalling pathway through deubiquitinating and stabilizing tumour-suppressor LKB1." Biochemical and Biophysical Research Communications 529, no. 4 (September 2020): 1025–32. http://dx.doi.org/10.1016/j.bbrc.2020.05.223.
Повний текст джерелаRegina, Sandra, Jean-Baptiste Valentin, Sébastien Lachot, Bruno Giraudeau, Jerome Rollin, and Yves Gruel. "Alterations of P53 and PTEN Genes Are Associated with Increased TF Expression and Reduced Survival in Non Small Cell Lung Cancer." Blood 112, no. 11 (November 16, 2008): 1032. http://dx.doi.org/10.1182/blood.v112.11.1032.1032.
Повний текст джерелаTsai, Hui-Jen, Tsung-Ming Chang, Yan-Shen Shan, Pei-Yi Chu, Shih Sheng Jiang, Wen-Chun Hung, Yu-Lin Chen, Hsu-Chi Tu, and Li-Tzong Chen. "The regulatory role of PTEN and LKB1 on mTOR pathway in pancreatic neuroendocrien tumors." Pancreatology 17, no. 3 (July 2017): S11. http://dx.doi.org/10.1016/j.pan.2017.05.035.
Повний текст джерелаGreen, Alexa S., Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Didier Bouscary, and Jerome Tamburini. "LKB1/AMPK/mTOR signaling pathway in hematological malignancies: From metabolism to cancer cell biology." Cell Cycle 10, no. 13 (July 2011): 2115–20. http://dx.doi.org/10.4161/cc.10.13.16244.
Повний текст джерелаLazo-de-la-Vega-Monroy, Maria-Luisa, Karen-Alejandra Mata-Tapia, Juan-Antonio Garcia-Santillan, Maria-Angelica Corona-Figueroa, Martha-Isabel Gonzalez-Dominguez, Hector-Manuel Gomez-Zapata, Juan-Manuel Malacara, Leonel Daza-Benitez, and Gloria Barbosa-Sabanero. "Association of placental nutrient sensing pathways with birth weight." Reproduction 160, no. 3 (September 2020): 455–68. http://dx.doi.org/10.1530/rep-20-0186.
Повний текст джерелаÁvalos, Yenniffer, Jimena Canales, Roberto Bravo-Sagua, Alfredo Criollo, Sergio Lavandero, and Andrew F. G. Quest. "Tumor Suppression and Promotion by Autophagy." BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/603980.
Повний текст джерелаTanwar, Pradeep S., Tomoko Kaneko-Tarui, LiHua Zhang, and Jose M. Teixeira. "Altered LKB1/AMPK/TSC1/TSC2/mTOR signaling causes disruption of Sertoli cell polarity and spermatogenesis." Human Molecular Genetics 21, no. 20 (July 12, 2012): 4394–405. http://dx.doi.org/10.1093/hmg/dds272.
Повний текст джерелаLiemburg-Apers, Dania C., Jori A. L. Wagenaars, Jan A. M. Smeitink, Peter H. G. M. Willems, and Werner J. H. Koopman. "Acute stimulation of glucose influx upon mitoenergetic dysfunction requires LKB1, AMPK, Sirt2 and mTOR–RAPTOR." Journal of Cell Science 129, no. 23 (October 28, 2016): 4411–23. http://dx.doi.org/10.1242/jcs.194480.
Повний текст джерелаVila-Bedmar, Rocio, Margarita Lorenzo, and Sonia Fernández-Veledo. "Adenosine 5′-Monophosphate-Activated Protein Kinase-Mammalian Target of Rapamycin Cross Talk Regulates Brown Adipocyte Differentiation." Endocrinology 151, no. 3 (February 4, 2010): 980–92. http://dx.doi.org/10.1210/en.2009-0810.
Повний текст джерелаShackelford, D. B., D. S. Vasquez, J. Corbeil, S. Wu, M. Leblanc, C. L. Wu, D. R. Vera, and R. J. Shaw. "mTOR and HIF-1 -mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome." Proceedings of the National Academy of Sciences 106, no. 27 (June 18, 2009): 11137–42. http://dx.doi.org/10.1073/pnas.0900465106.
Повний текст джерелаDong, Li-xia, Lin-lin Sun, Xia Zhang, Li Pan, Lin-juan Lian, Zhe Chen, and Dian-sheng Zhong. "Negative regulation of mTOR activity by LKB1-AMPK signaling in non-small cell lung cancer cells." Acta Pharmacologica Sinica 34, no. 2 (November 26, 2012): 314–18. http://dx.doi.org/10.1038/aps.2012.143.
Повний текст джерелаWildenberg, Manon, Anne Christine Vos, Marjolijn Duijvestein, Auke P. Verhaar, Daniel W. Hommes, and Gijs R. van den Brink. "Tu1945 Induction of Autophagy Upon DC-T Cell Contact is Mediated by LKB1-AMPK-mTOR Signalling." Gastroenterology 142, no. 5 (May 2012): S—884. http://dx.doi.org/10.1016/s0016-5085(12)63432-5.
Повний текст джерелаWildenberg, M. E., A. C. Vos, M. Duijvestein, A. Verhaar, G. van den Brink, and D. W. Hommes. "OP03 Induction of autophagy upon DC-T cell contact is mediated by LKB1 AMPK mTOR signalling." Journal of Crohn's and Colitis 6 (February 2012): S2. http://dx.doi.org/10.1016/s1873-9946(12)60004-x.
Повний текст джерелаHan, Jie, Huimin Liang, Derun Tian, Jianying Du, Qiming Wang, Pengjiao Xi, Haomin Wang, and Yongmei Li. "mTOR remains unchanged in diet-resistant (DR) rats despite impaired LKB1/AMPK cascade in adipose tissue." Biochemical and Biophysical Research Communications 476, no. 4 (August 2016): 333–39. http://dx.doi.org/10.1016/j.bbrc.2016.05.123.
Повний текст джерелаBorthakur, Gautam, Michael Andreeff, Kevin R. Coombes, Yi Hua Qiu, Seshagiri Duvvuri, Nianxiang Zhang, Vivian Ruvolo, et al. "High Expression of Autophagy Related Proteins Negatively Impacts Clinical Outcomes in Acute Myelogenous Leukemia–Time to Target Autophagy to Improve Therapy Outcomes?" Blood 118, no. 21 (November 18, 2011): 2513. http://dx.doi.org/10.1182/blood.v118.21.2513.2513.
Повний текст джерелаHou, Yawei, Yameng Li, Yichuan Wang, Wenpu Li, and Zhenwei Xiao. "Screening and Analysis of Key Genes in miRNA-mRNA Regulatory Network of Membranous Nephropathy." Journal of Healthcare Engineering 2021 (November 16, 2021): 1–13. http://dx.doi.org/10.1155/2021/5331948.
Повний текст джерелаGoel, MadhuMati, Annu Makker, AbbasAli Mahdi, Vikram Bhatia, Vinita Das, Anjoo Agarwal, and Amita Pandey. "PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas." Indian Journal of Medical Research 143, no. 7 (2016): 112. http://dx.doi.org/10.4103/0971-5916.191808.
Повний текст джерелаNguyen, H. B., J. T. Babcock, C. D. Wells, and L. A. Quilliam. "LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap." Oncogene 32, no. 35 (October 1, 2012): 4100–4109. http://dx.doi.org/10.1038/onc.2012.431.
Повний текст джерелаLai, L. P., B. N. Lilley, J. R. Sanes, and A. P. McMahon. "Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation." Proceedings of the National Academy of Sciences 110, no. 48 (November 11, 2013): 19450–55. http://dx.doi.org/10.1073/pnas.1309001110.
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