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Lamandé, Lydia, and Aurelio Munoz. "Stabilisation de cations oxophosphenium par liaisons datives P←N." Tetrahedron Letters 32, no. 1 (January 1991): 75–78. http://dx.doi.org/10.1016/s0040-4039(00)71222-6.
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Merniz, Salah, Louiza Himed, Mahieddine Mokhtari та Abdelhamid Mousser. "Marquage du 2-aminothiazole avec une unité cyclohexadiène fer tricabonyle. Étude structurale et activité antibactérienne du complexe marqué (1-4-η-5-N-2-aminothiazoliocyclohexa-1,3-diène) fer tricarbonyle". Canadian Journal of Chemistry 97, № 10 (жовтень 2019): 704–10. http://dx.doi.org/10.1139/cjc-2019-0016.
Повний текст джерелаАнотація:
La réaction du 2-aminothiazole (C3H4N2S) avec le complexe tétrafluoroborate de (1-4-η-5-N-pyridiniocyclohexa-1,3-diène) fer tricarbonyle [C11H12NFe(CO)3]+[BF4]− (1), précurseur du cation marqueur [(1-5-η-C6H7)Fe(CO)3]+ donne un nouveau complexe de formule C9H10N2SFe(CO)3, le (1-4-η-5-N-2-aminothiazolocyclohexa-1,3-diène) fer tricarbonyle (2). La structure de ce complexe a été caractérisée par les méthodes spectroscopiques IR et RMN 1H suivies d’une étude structurale par diffraction des rayons X, qui a montré que le complexe marqué 2 adopte stéréosélectivement une configuration exo. Dans l’édifice cristallin, les composants de la structure sont liés par des liaisons hydrogènes intermoléculaires de type N–H⋯N formant des chaînes dimériques le long de l’axe b. L’évaluation de l’activité antimicrobienne du ligand libre 2-aminothiazole a montré une activité antibactérienne importante. Après sa complexation par le marqueur organo fer tricarbonyle, cette activité a augmenté.
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Sanna, Maria Eleonora. "Le ��choix rationnel�� de la morale sexuelle catholique, ou les liaisons entre �glise et n�olib�ralisme." Raison publique N�20, no. 1 (2016): 193. http://dx.doi.org/10.3917/rpub.020.0193.
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Perera, Sharnel Miriam, Clare O’Callaghan, Anna Ugalde, Olinda Santin, Cassandra Beer, G. Prue, Katherine Lane, Gerard G. Hanna, and Penelope Schofield. "Codesigning a supportive online resource for Australian cancer carers: a thematic analysis of informal carers’ and healthcare professionals’ perspectives about carers’ responsibilities and content needs." BMJ Open 11, no. 10 (October 2021): e055026. http://dx.doi.org/10.1136/bmjopen-2021-055026.
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ObjectiveTo gather preliminary qualitative data that will assist in the codesign and development of a new informational and supportive website to assist informal cancer carers in Australia.Design and settingUtilising a previously tested codesign process, informal carers’ experiences and perspectives, including those of healthcare professionals’, were examined via focus groups and/or interviews. Data were analysed via thematic analysis.ParticipantsRural (n=9) and urban (n=11) carers’, and healthcare professionals’ (n=8) perspectives were collected. Carers participated in a focus group (n=9) or telephone interview (n=11). Healthcare professionals completed an interview (n=6) or online survey (n=2).ResultsRural and urban carers typically felt ill prepared for their multitudinal caregiving responsibilities. Supporting patient-to-healthcare professional liaisons could especially challenge. Carers’ biopsychosocial and fiscal strains were affected by patients’ hardships and available informal supports. Rural carers described greater social support than urban carers. Both rural and urban carers also described discontentment related to a carer neglecting healthcare system. Both carers and healthcare professionals endorsed the need for a user-friendly, carer-specific website encompassing practical information and resources, peer-driven advice and evidence-based illness information, tailored to the Australian context.ConclusionsCarers and healthcare professionals recognise the pressing need for an Australian, cancer carer-specific online resource. Findings will inform the next phase, where a resource will be designed, developed and tested.
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Wilhelm, Therese, Maha Said, and Valeria Naim. "DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons." Genes 11, no. 6 (June 10, 2020): 642. http://dx.doi.org/10.3390/genes11060642.
Повний текст джерелаАнотація:
Chromosomal instability (CIN) is associated with many human diseases, including neurodevelopmental or neurodegenerative conditions, age-related disorders and cancer, and is a key driver for disease initiation and progression. A major source of structural chromosome instability (s-CIN) leading to structural chromosome aberrations is “replication stress”, a condition in which stalled or slowly progressing replication forks interfere with timely and error-free completion of the S phase. On the other hand, mitotic errors that result in chromosome mis-segregation are the cause of numerical chromosome instability (n-CIN) and aneuploidy. In this review, we will discuss recent evidence showing that these two forms of chromosomal instability can be mechanistically interlinked. We first summarize how replication stress causes structural and numerical CIN, focusing on mechanisms such as mitotic rescue of replication stress (MRRS) and centriole disengagement, which prevent or contribute to specific types of structural chromosome aberrations and segregation errors. We describe the main outcomes of segregation errors and how micronucleation and aneuploidy can be the key stimuli promoting inflammation, senescence, or chromothripsis. At the end, we discuss how CIN can reduce cellular fitness and may behave as an anticancer barrier in noncancerous cells or precancerous lesions, whereas it fuels genomic instability in the context of cancer, and how our current knowledge may be exploited for developing cancer therapies.
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Testa, Maria, Jennifer A. Livingston, and Weijun Wang. "Dangerous Liaisons: The Role of Hookups and Heavy Episodic Drinking in College Sexual Victimization." Violence and Victims 34, no. 3 (June 1, 2019): 492–507. http://dx.doi.org/10.1891/0886-6708.vv-d-18-00075.
Повний текст джерелаАнотація:
Heavy episodic drinking (HED) and hookups increase college women's vulnerability to sexual victimization. We examined whether the effect of HED on first year college sexual victimization severity was mediated via hookups, that is, casual sexual encounters between individuals not in a relationship. We also tested the hypothesis that greater sexual limit-setting would attenuate the positive effect of hookups on sexual victimization. Freshman women (N = 335) were recruited by e-mail to complete an online survey regarding their college drinking and sexual experiences. The effect of HED frequency on sexual victimization was completely mediated via hookups. There was a significant indirect path from HED to victimization via alcohol-involved hookups; the path through sober hookups was not significant. We found some support for the hypothesis that sexual limit-setting reduced the impact of hookups on sexual victimization severity. Findings suggest the importance of targeting sexual behavior, which frequently occurs in conjunction with drinking, as a way of preventing college sexual victimization.
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Murdock, Vicki, Jim Ward, Jan Ligon, and Shinaz Jindani. "Identifying, Assessing, and Enhancing Field Instructor Competencies." Journal of Baccalaureate Social Work 12, no. 1 (September 1, 2006): 165–83. http://dx.doi.org/10.18084/1084-7219.12.1.165.
Повний текст джерелаАнотація:
Social work education currently prepares the beginning practitioner, but it does not offer preparation for becoming a teacher of social work as a field instructor. This study sought to explore BSW and MSW field instructor competency through the views of field directors/coordinators of CSWE-accredited programs who recruit, train, and work with agency-based social work field instructors. Field directors/coordinators (N= 180) rated the integration of classroom and field learning highest as a training issue for their field instructors, and they ranked their instructors weakest in their ability to integrate classroom and field. No statistically significant differences were reported between BSW and MSW field instructors in strengths, concerns, or training issues. The exploratory survey instrument and a self-assessment variation are appended as possible assessment and measurement tools for field instructors, directors, and liaisons to improve standards and enhance outcome measures for quality improvement and accreditation purposes.
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Orsulic-Jeras, Silvia, Ashlee Cordell, Sara Powers, Farida Ejaz, and Lisbeth Sanders. "RECRUITING AND RETAINING RESIDENTIAL CARE COMMUNITIES DURING THE COVID-19 PANDEMIC: LESSONS LEARNED." Innovation in Aging 7, Supplement_1 (December 1, 2023): 801. http://dx.doi.org/10.1093/geroni/igad104.2586.
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Abstract Demands within residential care communities have escalated throughout the Covid-19 pandemic as meeting basic care needs has become more critical. Non-pharmacological interventions that aim to alleviate care strain and promote person-centered care are even more important now, as residents have been significantly impacted by social isolation and loss. This presentation highlights successes and challenges faced by researchers and residential care communities related to study recruitment and retainment efforts during the Covid-19 pandemic while conducting a fidelity trial of LifeBio MemoryTM: a novel app-based product designed to collect life story information from persons living with dementia (PLWD). The target sample is comprised of residential care staff (n=60) and PLWD (n=242) across ten residential care communities in the state of Ohio. Successes presented include: 1) high enthusiasm for the study and 2) strong relationships built between researchers and site liaisons. Significant challenges faced include: 1) organization-wide staff shortages, 2) low overall resident census, and 3) Covid-19 outbreaks and quarantines. Key lessons learned include: 1) researchers and residential care communities face competing demands as a result of the Covid-19 pandemic and 2) the Covid-19 pandemic has changed the landscape of residential care and research. The importance of efficient field operations, supportive training resources, and contingency plans when conducting studies in residential care will be discussed.
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Cassidy, Omni, Dawn M. Eichen, Natasha L. Burke, Jacqueline Patmore, Allison Shore, Rachel M. Radin, Tracy Sbrocco, et al. "Engaging African American Adolescents and Stakeholders to Adapt Interpersonal Psychotherapy for Weight Gain Prevention." Journal of Black Psychology 44, no. 2 (December 21, 2017): 128–61. http://dx.doi.org/10.1177/0095798417747142.
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Developing culturally appropriate obesity prevention programs for African American (AA) adolescent girls that account for psychological risk factors is paramount to addressing health disparities. The current study was part of an investigation utilizing a community-based participatory research framework to gather qualitative data from urban AA girls, their caregivers, and community health liaisons to develop a novel obesity prevention program based on interpersonal psychotherapy for the prevention of excessive weight gain (IPT-WG). In the current study with urban AAs, data from seven focus groups (total sample size, N = 40) were analyzed using thematic analysis. Participants identified problematic eating behaviors, including binge or loss of control eating; highlighted the importance of interpersonal relationships, mood functioning, and eating; and supported the tenets of IPT-WG. While features of IPT-WG generally resonated with participants, culturally based modifications were suggested. These data will be used to inform the development of a culturally relevant IPT-WG program.
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Foba, Ibrahima, and Et Al. "Analyse bactériologique et parasitologique des selles chez les professionnels de la restauration collective dans une industrie alimentaire au Mali." Revue Malienne d'Infectiologie et de Microbiologie 17, no. 1 (April 30, 2022): 65–71. http://dx.doi.org/10.53597/remim.v17i1.2229.
Повний текст джерелаАнотація:
But: le but de notre étude consistait à déterminer la prévalence du portage bactériologique et parasitologique des selles chez les professionnels de la restauration collective de la société Bramali. Méthodologie: nous avions mené une étude rétrospective, descriptive et analytique de trois années de prélèvements de selles. Elle était réalisée chez des professionnels de la restauration affectés à la cantine de la société Bramali. Les prélèvements étaient effectués périodiquement tous les six mois. Les données étaient saisies sur le logiciel Excel Microsoft 365 et analysées sur Epi-info 7.2.4.0. Le test de khi2 était utilisé pour les liaisons statistiques. Le seuil de risque d’erreur était à 5% (p<0,05). Résultats: Douze travailleurs étaient suivis, composés essentiellement de femmes (83,3%). La moyenne d’âge était de 35,8 ans. Les ¾ des travailleurs avaient plus de 5 ans d’ancienneté dans le poste. Soixante prélèvements de selles avaient été effectués chez ces travailleurs et sept étaient porteurs de germes (11,7%). Les prélèvements porteurs de bactéries et de parasites représentaient respectivement 3,4% (n=2) et 5% (n=3). Les kystes d’Entamoeba histolytica étaient les plus répertoriés (42,8%), suivis de Candida albicans (28,6%) et Salmonella sp (28,6%). Aucun lien statistique (p˃0,05) n’avait été retrouvé entre le portage de germes et, le lieu de résidence, le sexe, l’ancienneté au poste, le niveau d’instruction. Conclusion: Cette étude a montré l’importance du contrôle des agents travaillant dans la chaine alimentaire. C’est pourquoi, le respect strict des mesures d’hygiène en restauration collective doit être de rigueur. Cela permettrait d’éviter la propagation des maladies du péril fécal en milieu professionnel
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Munly, Kelly, and Lauren Jacobson. "AGE-INCLUSIVE PRINCIPLES ON CAMPUS: EMBRACING DIVERSITY ACROSS THE LIFESPAN." Innovation in Aging 6, Supplement_1 (November 1, 2022): 760. http://dx.doi.org/10.1093/geroni/igac059.2758.
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Abstract In this poster, researchers based at a Mid-Atlantic university campus provide an understanding of their evaluative steps informing an adaptation of the Diversity Circles program to include a multigenerational component, supporting diversity across the lifespan. Project methods and analysis have been informed by critical theoretical frameworks, including feminist gerontology, that illuminate the invisibility of age, even in the context of intersectional work. Pilot feedback from five participants from a condensed program in an Adult Development and Aging course informed the interview approach. Post-program semi-structured interviews, with program participants, including students and older adults (n=7), and community stakeholders (n=18), provided feedback on diversity needs at the campus and in the surrounding community, as well as on program content and experience and opportunity for further curriculum integration of concepts of age-friendliness, ageism, and age-awareness. Stakeholders interviewed included community practicum liaisons, university advising and student affairs staff, faculty and staff previously engaging in diversity-related activities, university administrators, university personnel attending to enrollment matters, and staff and faculty interested in student-centered curriculum design. Semi-structured interviews were chosen for data collection because of their capacity to provide saturated data from a small, purposeful sample. Focused codes emergent from the interviews included both a) suggestions for curriculum adaptation and modification as well as the value of existing content and b) issues of age-friendliness and ageism more generally. The research team looks toward incorporating suggestions within their findings in an expansion of the program on their campus, and disseminating findings for the benefit of other campuses’ programs.
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de Hooge, M., M. Hanlon, A. Alunno, A. Sepriano, K. Lauper, and F. Rivellese. "OP0077 THE EMERGING EULAR NETWORK (EMEUNET): AN INTERNATIONAL SURVEY REFLECTING ON A TEN-YEAR JOURNEY." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 41.2–42. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2706.
Повний текст джерелаАнотація:
Background:The Emerging EULAR NETwork (EMEUNET), founded in 2009, aims to promote education, foster research collaborations and facilitate the integration of young researchers and rheumatologists within EULAR.Objectives:After 10 years, we aimed to interview our members to assess how EMEUNET is fulfilling its goals, understand if there are unmet needs and explore new ideas.Methods:In July 2019 a survey was circulated for 3 months among EMEUNET members via its social media channels. The survey contained 18 closed and 2 open items, in addition to general questions on age, job and country of origin and work.Results:Out of 124 total respondents, most completed all items (120/124) and only a minority had some missing items (4/124). A little over half of the respondents were female (n=69, 54.8%) and median age was 33y (range 25y-42y). Most respondents were born (n=109, 88.6%) and/or worked in Europe (n=114, 92.7%) (fig. 1), although there was also a representation from extra-European countries, which is in line with the general EMEUNET membership (https://emeunet.eular.org/map.cfm).Figure 1.Country of origin and where respondents work at the time of completing the EMEUNET VISE questionnaire.11 (9.1%) had been EMEUNET members for less than 2 years, 81 (66.9%) for 2-5years and 29 (24.0%) for more than 5 years.Figure 2 shows a clear link between the respondents’ perception of EMEUNET aim(s) and the actual aims of EMEUNET set out in our mission statement (https://emeunet.eular.org/mission_statement.cfm).Figure 2.The links between what participants would like to see as EMEUNET aims and the aims of EMEUNET as they are nowMost of the respondents got to know about EMEUNET through a friend/colleague in Rheumatology (n=67, 54.0%), at EULAR/ACR annual conferences (n=32, 25.8%), via social media (n=9, 7.3%), other international meeting (n=6, 4.8%), national Rheumatology meeting (n=6, 4.8%) or via the EMEUNETs country liaisons (n=4, 3.2%).29 respondents (24%) were part of the EMEUNET working group (WG), 43% (n=53) applied before to be part of the WG, 24% (n=29) never applied and 15% (n=19) did not know what the WG was. Most of the respondents who never applied to the WG thought it to be too time consuming. Only 21 (16.9%) felt there was a subgroup in the WG missing and most of those (n=8, 38.1%) found this should fully focus on research collaborations, which is actually part of the general aims of EMEUNET and a focus of all Working Groups.Only a relatively small portion of EMEUNET of respondents (<5%) stated to have approached EMEUNET with their ideas. Although 90.2% (n=110) felt that the opportunity to submit new ideas is a good initiative, only 52.5% (n=..) knew that such possibilities exists. This suggests that EMEUNET could do more to make members aware of this possibility. Additionally, while the main reasons for not contacting EMEUNET with an idea were ‘not having one’ (41.9%) or having ‘no time’ (34.9%), 20.9% feels their ideas would not be received well, which is another aspect offering room for improvement.Twice a year, EMEUNET organises networking events (NE) for their members to discuss their work in an informal setting. We found that 56/120 (46.7%) of the respondents prefer a low-budget (<€20) event, including an activity and the possibility to network, accompanied by drinks and bites. This is much in line with EMEUNETs past NE. In addition, past NEs were often mentioned as an example of ideal events.Conclusion:Awareness on EMEUNET often comes from colleagues and international conferences in rheumatology, which coincides with one of the focuses of EMEUNET to increase visibility in the last 10 years. Expectations about NE are in line with the previously organised NE.Areas for improvement are dissemination of information on the EMEUNET WG, the possibility to submit ideas -which is open to all members- and the increased focus on research collaboration, an aspect on which we are actively working as EMEUNET is fully engaged with the newly launched EULAR Virtual Research Centre.Disclosure of Interests:None declared
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Lessard, Laura, Rena Hallam, Deborah Drain, and Laurie Ruggiero. "COVID-19 Vaccination Status and Attitudes of Family Child Care Providers in Delaware, September 2021." Vaccines 10, no. 3 (March 19, 2022): 477. http://dx.doi.org/10.3390/vaccines10030477.
Повний текст джерелаАнотація:
Child care providers, including family child care (FCC) providers, are viewed as trusted sources of information for the parents and families they serve, and their vaccine behavior has been shown to be associated with parent beliefs and behaviors. This study sought to describe the COVID-19 vaccine behaviors and attitudes among FCC providers in Delaware. An online survey was distributed to all licensed FCC providers (N = 541) in September 2021. Survey items were drawn from validated instruments and assessed vaccination status, attitudes, and confidence in their ability to discuss COVID-19 vaccines with families. In total, 168 responses were recorded (31% response rate); 69.8% of respondents were fully vaccinated against COVID-19. The majority indicated that they would require (11.4%) or recommend (42.1%) the vaccine for children in their care, once approved by the FDA. Providers reported high levels of confidence in their ability to discuss both the benefits and risks of COVID-19 vaccines. FCC providers should be considered key messengers for the families they serve and may be helpful liaisons with state and local vaccination efforts. Input from FCC providers could be used to develop vaccine messaging and materials that are clear, consistent, and culturally responsive to the families of the children in their care.
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Newbury-Birch, Dorothy, Stephanie Scott, Amy O’Donnell, Simon Coulton, Denise Howel, Elaine McColl, Elaine Stamp, et al. "A pilot feasibility cluster randomised controlled trial of screening and brief alcohol intervention to prevent hazardous drinking in young people aged 14–15 years in a high school setting (SIPS JR-HIGH)." Public Health Research 2, no. 6 (November 2014): 1–208. http://dx.doi.org/10.3310/phr02060.
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BackgroundApproximately 33% of 15- to 16-year-olds in England report alcohol intoxication in the past month. This present work builds on the evidence base by focusing on Alcohol Screening and Brief Intervention (ASBI) to reduce hazardous drinking in younger adolescents.ObjectivesTo explore the feasibility and acceptability of a future definitive cluster randomised controlled trial (cRCT) of ASBI in a school setting to staff, young people and parents; to explore the fidelity of the interventions as delivered by school learning mentors; to estimate the parameters for the design of a definitive cRCT of brief alcohol intervention, including rates of eligibility, consent, participation and retention at 12 months; and to pilot the collection of cost and resource-use data to inform the cost-effectiveness/utility analysis in a definitive trial.SettingSeven schools across one geographical area in North East England.MethodsFeasibility of trial processes, recruitment and retention and a qualitative evaluation examined facilitators and barriers to the use of ASBI approaches in the school setting in this age group. A three-arm pilot cRCT (with randomisation at the school level) with qualitative evaluation to assess the feasibility of a future definitive cRCT of the effectiveness and cost-effectiveness of ASBI in a school setting, with an integrated qualitative component. The trial ran in parallel with a repeated cross-sectional survey, which facilitated screening for the trial.ParticipantsYear 10 school pupils (aged 14–15 years).InterventionsYoung people who screened positive on a single alcohol screening question, and consented to take part, were randomised to one of three groups: (1) feedback that their drinking habits may be risky and provision of an advice leaflet (control condition,n = two schools); (2) feedback as for the control condition plus a 30-minute brief interactive session, which combined structured advice and motivational interviewing techniques, delivered by the school learning mentor (intervention 1,n = two schools); or (3) feedback as for the control condition plus a 30-minute brief interactive session as for intervention 1 plus a 60-minute session involving family members delivered by the school learning mentor (intervention 2,n = three schools). Young people were followed up at 12 months.Main outcome measuresFeasibility and acceptability.RandomisationRandomisation was carried out at the school level. Randomisation achieved balance on two school-level variables (numbers of pupils in school year and proportion receiving free school meals).BlindingSchool staff, young people and researchers were not blind to the intervention allocated.ResultsA total of 229 young people were eligible for the trial; 182 (79.5%) were randomised (control,n = 53; intervention 1,n = 54; intervention 2,n = 75). Of the 75 randomised to intervention 2, 67 received intervention 1 (89%). Eight received both intervention 1 and intervention 2 (11%). In total, 160 out of 182 were successfully followed up at 12 months (88%). Interviews were carried out with six school lead liaisons, 13 learning mentors, 27 young people and seven parents (n = 53). Analysis shows that the school setting is a feasible and acceptable place to carry out ASBI, with learning mentors seen as suitable people to do this. Intervention 2 was not seen as feasible or acceptable by school staff, parents or young people.Outcomes/conclusionsIt is feasible and acceptable to carry out a trial of the effectiveness and cost-effectiveness of single-session ASBI with young people in the school setting, with learning mentors delivering the intervention. Future work should include a definitive study that does not include a parental arm.Trial registrationCurrent Controlled Trials ISRCTN07073105.FundingThe National Institute for Health Research Public Health Research programme.
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Cabrera, Michelle T., Karen L. Christopher, Megan E. Collins, Eliesa Ing, Grace Sun, Jeff H. Pettey, Shira S. Simon, et al. "Utilizing a Professionalism Mentor to Address Sexual Harassment in Academic Ophthalmology." Journal of Academic Ophthalmology 13, no. 01 (January 2021): e11-e18. http://dx.doi.org/10.1055/s-0040-1722745.
Повний текст джерелаАнотація:
Abstract Objective This study assesses a new departmental role—a professionalism mentor—who receives sexual harassment reporting, liaisons with campus resources, and organizes educational sessions. Study Design Multicenter randomized controlled survey study. Methods Academic ophthalmology departments in the United States were randomized to a professionalism mentor group (n = 9) and a control group (n = 7). Among both pre- and postsurveys, 605 faculty and trainee responses were received and 546 were complete. The intervention group was assigned a professionalism mentor with educational session for a 6- to 10-month period. Sexual harassment and reporting rate change over time were compared between the two groups. Results Among 546 anonymous responses, 16% experienced workplace sexual harassment during the prior 10 months. Location in the South or Midwest was a risk factor (p < 0.001). Victims were mostly women (76%), including residents/fellows (46%) and academic attendings (49%); perpetrators included patients (35%) and academic attendings (35%). Departments with and without a professionalism mentor had stable harassment from pre- to postsurvey (p = 0.95 comparing change). The professionalism mentor group had an increase in reporting to an authority from pre- to postsurvey (7–23%), whereas the control group had a decrease (27–12%; p = 0.07 comparing change). Most faculty and trainees in the interventional arm of this study recommended instituting a professionalism mentor with educational session (66% presurvey and 68% postsurvey), compared with educational session alone (25% presurvey and 23% postsurvey), or neither (9% presurvey and 9% postsurvey). Residency program directors in the professionalism mentor group even more strongly supported instituting both a professionalism mentor and educational program (100% presurvey and 100% postsurvey) as opposed to educational program alone (0% presurvey and 0% postsurvey) or neither (0% presurvey and 0% postsurvey). Conclusion This study identified a high sexual harassment rate in academic ophthalmology departments over a brief period. The presence of a professionalism mentor was viewed favorably and may lead to increased reporting.
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DOREAU, M., V. FIEVEZ, A. TROEGELER-MEYNADIER, and F. GLASSER. "Métabolisme ruminal et digestion des acides gras longs chez le ruminant : le point des connaissances récentes." INRAE Productions Animales 25, no. 4 (October 2, 2012): 361–74. http://dx.doi.org/10.20870/productions-animales.2012.25.4.3224.
Повний текст джерелаАнотація:
La maîtrise de la composition en Acides Gras (AG) des produits animaux est l'une des composantes de l'amélioration de leur qualité nutritionnelle, passant par exemple par une diminution des AG saturés réputés athérogènes et une augmentation des AG polyinsaturés de la série n-3 (oméga-3) dans les produits de ruminants. Chez les ruminants, les AG longs ingérés subissent des transformations structurales importantes dans le rumen, principalement des réactions de saturation, trans isomérisation et conjugaison des doubles liaisons. La composition des AG arrivant dans l'intestin grêle puis absorbés est donc complètement différente de celle des AG ingérés, avec de plus l'apparition de très nombreux isomères issus de l'action du microbiote ruminal sur les AG. Ces phénomènes sont très étudiés depuis longtemps, mais les récents progrès dans l'analyse des AG d'une part et dans l'étude du microbiote ruminal d'autre part ont permis d'affiner les connaissances depuis quelques années. Cet article présente l'état des connaissances sur les mécanismes ruminaux de lipolyse et de biohydrogénation des AG insaturés alimentaires dans le rumen (y compris des données récentes sur les AG à 20 et 22 carbones), l'ampleur de la biohydrogénation et l'effet des facteurs alimentaires, les flux et la composition des AG arrivant dans l'intestin, la protection des lipides contre la biohydrogénation et l'absorption intestinale des AG. Ces connaissances permettent de mieux comprendre et prévoir le devenir des AG ingérés et donc potentiellement de mieux maîtriser la composition en AG des produits de ruminants.
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Mingo, Chivon, and Collins Airhihenbuwa. "Chronic Disease Self-Management: Behavioral Intervention Preferences Informed by the PEN-3 Cultural Model." Innovation in Aging 4, Supplement_1 (December 1, 2020): 478. http://dx.doi.org/10.1093/geroni/igaa057.1547.
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Abstract Chronic Disease Self-Management Program (CDSMP) is an evidence-based program shown to improve health status, healthcare utilization, and health behaviors among individuals diagnosed with chronic conditions. Aging African Americans, a population at a greater risk of chronic disease diagnosis and burden, are underrepresented in the utilization of self-management behavioral programs. Previous research suggested that cultural distinctions (e.g., values, beliefs, preferences, experiences) impact the participation of racial/ethnic minorities in health-related research, health behavior outcomes, and healthcare utilization. Little is known about unique cultural influences on CDSMP utilization among this target group. To our knowledge, no research has applied a culture-specific theory to understand preferences or use of CDSMP among aging African Americans. Guided by the PEN-3 cultural model, this study examines preferences, barriers, and facilitators that may influence CDSMP utilization for the management of diagnosed chronic conditions. Using a qualitative research design, African Americans (N=50) from six Atlanta Metropolitan faith-based organizations participated in the 6-week CDSMP and one of six focus groups. Participants were largely female (70%) experiencing multiple chronic conditions (M=2) with an average age of 70. Focus groups were transcribed, and a thematic analysis was applied to identify emergent themes. Participants preferred programs that included family, community liaisons, and relevant advertisement material suggesting the importance of cultural identity. Accessing CDSMP at a familiar location with an endorsement of program benefit from trusted sources suggests the importance of relationship and expectations. Findings shed light on factors that may cause aging African Americans to embrace or avoid CDSMP as a healthcare option.
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SAUVANT, D., and P. BAS. "La digestion des lipides chez le ruminant." INRAE Productions Animales 14, no. 5 (December 17, 2001): 303–10. http://dx.doi.org/10.20870/productions-animales.2001.14.5.3754.
Повний текст джерелаАнотація:
La digestion des lipides chez les ruminants présente un regain d’intérêt en raison de la présence, dans les produits de ces animaux, d’acides gras (AG) ayant une influence technologique ou diététique de mieux en mieux démontrée. Dans le réticulo-rumen, la digestion des AG alimentaires correspond au phénomène d’hydrogénation et d’isomérisation. Les micro-organismes, en particulier les bactéries attachées aux particules, sont plus riches en AG que les rations offertes aux ruminants. La composition en AG de ces microorganismes se caractérise par une grande diversité moléculaire (plus de 50 AG) et la domination de deux d’entre eux : C16:0 et surtout C18:0. Cette composition peut être influencée par les caractéristiques de la ration : richesse en concentré et composition en AG lorsqu’il y a supplémentation en matières grasses. Le flux d’AG au duodénum (Y), exprimés en % de la matière sèche ingérée (MSI), est très corrélé au flux ingéré (X, % MSI) : Y = 0,83 X + 0,84 (n = 116, R2 = 0,94, etr = 0,54). Il dépend également de l’importance des synthèses microbiennes ruminales. En moyenne, les 2/3 des doubles liaisons des AG ingérés sont hydrogénées dans le réticulo-rumen. L’intensité de l’hydrogénation diminue avec des rations riches en concentrés et celles qui sont ingérées en grande quantité. Des équations proposées permettent de prédire les flux duodénaux des principaux AG en fonction des flux ingérés. La digestibilité intestinale des AG varie entre 65 et 75 % environ. La nature de la matière grasse apportée semble influencer légèrement cette digestibilité. L’ensemble des données traitées permet de prédire les flux absorbés des principaux AG chez les ruminants et de formuler des régimes sur cette base.
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Septaria, Kiki, Atika Fatharani, and Arnelia Dwi Yasa. "COVID-19 is a Conspiracy Disease? Diagnostic Mental Models and Students' Cognitive Abilities." Jurnal Penelitian dan Pengkajian Ilmu Pendidikan: e-Saintika 6, no. 1 (March 26, 2022): 18–32. http://dx.doi.org/10.36312/esaintika.v6i1.561.
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Countless research has been published on the impact of covid-19 on improvements in teaching techniques, activities, and motivational beliefs. Most research refers to a human's response before learning without testing students' comprehension and literacy linked to covid-19. This study adopted a qualitative approach, with a questionnaire serving as the primary research tool. Alternatively, the current study looks into students' cognitive and portrays their mental model of COVID-19. At the Islamic University of Lamongan, 30 students from the science education department and 30 students from the environmental health department took part. Students are chosen as transformational leaders and liaisons between society's academic and social environments. The researchers gather data based on an open-ended assessment that evaluates the concepts, causation, methods, and strategies that must be implemented to prevent the transmission of COVID-19. Participants completed questionnaires prepared for educational purposes before and after learning. Inductive and iterative investigation of the descriptions of students' answers revealed cognitive outcomes and mental models. Each questionnaire form is then checked for validity using the SPSS v24 program. The authenticity of the questionnaire responses for each questionnaire > rcount (N = 60), indicating that each question is valid, whereas the reliability test using Cronbach's Alpha provides a score of 0.78 > 0.60, indicating that the questionnaire employed is trustworthy. Regarding educational, cognitive processes, the analysis shows that some colleagues believe that COVID-19 is a conspiracy, while others need to add sufficient scientific literacy to validate that COVID-19 is a disease. Even after learning, they can only make general ways to mitigate the propagation of COVID-19. The findings for student mental models revealed considerable changes in clarity and coherence, such as models at levels 1 through 5 with the highest student mental models. This study culminates with the implication that students require scientific literacy to effectively communicate about COVID-19 and check out false information in public.
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Seidman, Andrew David, Meredith M. Regan, Dawn L. Hershman, Larissa A. Korde, Jane Perlmutter, William E. Barlow, Larry Rubinstein, et al. "NCI Breast Cancer Steering Committee Working Group (WG) report on meaningful and appropriate endpoints for clinical trials (CT) in metastatic breast cancer (MBC)." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 1073. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.1073.
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1073 Background: There is significant heterogeneity in the natural history of MBC. Several recent randomized CT have yielded statistically significant advantages for the experimental arm, but neither led to regulatory approval nor practice change. Formal guidance for industry on CT endpoints provided by the US FDA in 2007 was not disease-specific. Patient-focused drug development is mandated by Prescription Drug User Fee Act V. Our WG sought to create specific consensus on endpoints for MBC CT focusing on subtype and line of therapy, with sensitivity to various stakeholders. Methods: A WG composed of medical oncologists, statisticians, advocates, FDA and NCI liaisons performed a systematic literature review of MBC natural history, CT endpoints by subtype (HR+/HER2-, HR+/HER+, HR-/HER2-, HR-/HER2+), and line of therapy (n = 146 papers). External expertise was obtained on industry perspectives, big data and real world evidence (RWE), and patient reported outcomes (PROs). WG members voted anonymously on statements and positions generated from deliberation. Results: The WG reached consensus on definitions relevant to contemporary CT endpoints. WG recommendations on the appropriate choice of OS or PFS are sensitive to expected post progression survival (PPS), and proportional and absolute gains. Currently, for HR-/HER2- MBC, OS is preferred as the optimal primary endpoint regardless of line of therapy; PFS is preferred in settings where expected PPS is longer. Toxicity can outweigh modest gains in PFS; scant data exist to gauge how patients value PFS gain vs toxicity. Where new agents may prolong PFS without impacting OS, exploring/validating graphic approaches that capture grade and timing of toxicity and PROs is warranted. An overview of WG Consensus Statements will be presented in detail. Conclusions: CT design for MBC should be sensitive to natural history (PPS), availability of other effective agents, PROs and toxicity burden. As unique subtypes (e.g. AR+) and novel therapies (e.g. immunotherapy) emerge, reassessment of relevant benchmarks is indicated. Rigorous big data approaches providing insights from RWE may inform CT endpoints in the future.
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Huyskens, P., and Th Zeegers-Huyskens. "Étude de la Liaison Hydrogène Dans les Complexes Butanol n-Butylamine n Par Résonance Magnétique Nucléaire." Bulletin des Sociétés Chimiques Belges 69, no. 5-6 (September 1, 2010): 267–81. http://dx.doi.org/10.1002/bscb.19600690502.
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Setlhare, Kesegofetse, Hannah Woodman, Amandeep Pahal, and James Hickmott. "An Audit to Assess the Quality of Ward Referrals Sent to City Hospital Liaison Psychiatry Team From Inpatients Wards D15, D17and D27, Between July 2021 to September 2021." BJPsych Open 8, S1 (June 2022): S173. http://dx.doi.org/10.1192/bjo.2022.483.
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AimsLiaison psychiatry provides psychiatric care to medical patients. Patients include those attending emergency departments, general hospital inpatients and outpatients. Liaison teams work hand in hand with several general hospital teams to offer advice, review and manage these patients. Over the last few months, the Liaison service in City Hospital have been receiving many inappropriate referrals. Inappropriate referrals are defined as patients who are referred to services, with one of the following reasons: 1.Insufficient presenting complaint2.No documented Past psychiatric history3.Insufficient Mental state Examination (MSE)4.No risk assessment5.No documented Drug/alcohol history6.Patients having not consented to referral.7.If one or more of the above criteria is not metOur aim was to evaluate the appropriateness of the referrals received from D15, D17, D27 inpatients wards in City Hospital over a 3-month period from July to September 2021. These wards were chosen as they commonly refer patients to liaison services.MethodsWe collated data retrospectively on the nature of all referrals from D15, D17 and D27 ward over a 3-month period. The patient referral portal was used, and referral content of each patient was analysed. An audit tool was devised to assess whether the referrals followed the liaison referral pathway and guidelines set by NHS England for referral structure to liaison services.Results18 patients were referred to the Liaison psychiatry from the three wards over the three-month period. We observed 77.8% (n = 14) of the referrals having insufficient information for the presenting complaints, whilst 22.2% (n = 4) of them did not state past psychiatric history. Approximately 94.4%(n = 17) did not state sufficient details of MSE. In 83.3% (n = 15) of referrals appropriate detailed risk assessment was not done, 27.8% (n = 5) of them did not have alcohol/ drug use stated and 22.2% (n = 4) of patients referred did not consent to the referral being made.ConclusionThe results demonstrated that ward referrals lack quality and contain inadequate information to allow for safe screening of patients and for the implementation of appropriate actions by the liaison team. A possible reason for inappropriate referrals may be due an existing knowledge gap and lack of confidence taking detailed psychiatric histories, assessing risk, and performing MSE in non-psychiatric trainees making referrals to liaison services.
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Rivière-Baudet, Monique, Abdelhay Khallaayoun, Jacques Satge, and Mohamed Ahra. "Liaison germanium-Azote Steriquement Encombree. II. Amines secondaires N-Monohalogenogermaniees." Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 22, no. 6 (June 1992): 683–701. http://dx.doi.org/10.1080/15533179208020239.
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Marquis, Eric, Jérôme Graton, Michel Berthelot, Aurélien Planchat та Christian Laurence. "Liaison hydrogène des arylamines : compétition des sites π et N". Canadian Journal of Chemistry 82, № 9 (1 вересня 2004): 1413–22. http://dx.doi.org/10.1139/v04-128.
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An IR study, in the region of OH stretching, of a reference hydrogen-bond donor, 4-fluorophenol, hydrogen bonded to primary, secondary, and tertiary arylamines differently substituted on the ring and on the nitrogen, shows the formation of two kinds of 1:1 complexes in CCl4 solution: an OH···π and an OH···N hydrogen-bonded complex. The IR method gives only access to a global complexation constant Kt. A method is proposed for separating Kt into a Kπ component for hydrogen bonding to the π system and a KN component for hydrogen bonding to the nitrogen atom. This method is validated by comparing the estimated Kπ and KN values to theoretically calculated descriptors of basicity: the nitrogen lone pair orientation towards the aromatic ring, the molecular electrostatic potentials around the nitrogen and the π cloud, and the enthalpy of hydrogen bonding of hydrogen fluoride with the π system of selected arylamines. The main electronic and steric factors governing the competition between π and N sites are analysed. The strongest π and N bases among the arylamines are julolidine and Tröger's base, respectively. Triphenylamine and diphenylamine, which are nitrogen Brønsted bases, become π bases in hydrogen bonding. Moreover, there is no correlation between the pKHB and the pKBH+ scales of basicity of arylamines. The use of the pKBH+ scale is therefore not recommended in hydrogen-bonding studies.Key words: hydrogen bonding, arylamines, pKHB scale, competition of π and N hydrogen-bonded sites.
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Hammes, B. A., J. A. Lee, M. A. Mathiason, M. T. Ertz, L. L. Sheldon, and R. S. Go. "Prevalence of written advance directives (AD) among cancer care providers at a community-based cancer center." Journal of Clinical Oncology 24, no. 18_suppl (June 20, 2006): 18563. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.18563.
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18563 Background: Cancer care providers frequently discuss AD with their patients. The providers’ own attitudes toward end-of-life planning likely influence the choices and actions of their patients. We investigated the prevalence of written AD among the care providers at our community-based cancer center. Methods: All cancer center employees who have face-to-face contacts with patients (N=170) were sent an email survey in October 2005. This included medical (physicians, 15), associate (physician assistants and nurse practitioners, 7), and support (nurses, radiation therapists, medical or nurse assistants, and patient liaisons; 148) staffs. We collected data on demographics, work history, and AD. Results: A reply was obtained from 136 (80%) individuals. There were more females (90.2%) and the median age was 43 years (range, 20–63). While 82.8% reported to have discussed their wishes regarding future life-sustaining medical care with those closest to them, only 35.1% had a written AD: medical (58.3%), associate (50%), and support staffs (32.2%). Among those with AD, only 66% had made their own care providers aware of this. The top 5 factors that influenced providers whether to have or not to have AD were: experience at work (36.6%), spouse/domestic partner (25.4%), time to complete written AD (23.9%), family members/friends (21.6%) and children (19.4%). Interestingly, no one considered medical condition or illness as a factor. Increased age was significantly associated with having AD (odds ratio: 1.068; 95% CI:1.029–1.108), while the sex, number of years working with cancer patients, provider role, and marital/living status were not. Among the medical and associate staffs, 55.6% reported routinely discussing AD with their patients. Although all medical/associate staffs rated themselves as knowledgeable about and comfortable with discussing AD, the group who had AD was more apt to rate themselves as very knowledgeable and very comfortable. Conclusions: Only about a third of all cancer care providers and about half of cancer physicians at our institution have a written AD. Despite work experience with a patient population having a high mortality rate, cancer care providers do not adequately communicate end-of-life planning to their own health care providers. No significant financial relationships to disclose.
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Bolondi, Giorgio, and Juan Migliore. "Classification of maximal rank curves in the liaison class L n." Mathematische Annalen 277, no. 4 (August 1987): 585–603. http://dx.doi.org/10.1007/bf01457859.
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Svedberg, Kaj. "Why is hitting A&E time targets so hard?: using Nudge theory and modelling to improve response times." BJPsych Open 7, S1 (June 2021): S223. http://dx.doi.org/10.1192/bjo.2021.595.
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AimsTo improve the one hour response times to referrals made to psychiatric Liaison in A&E without adding or changing available resources.MethodResponse time data of referrals made to the Homerton University Hospital psychiatric liaison service was collected dating back from August 2016 to October 2019 (n = 10225).A nudge was introduced in the form of a large display showing referrals arriving in real time in the staff office.Data was then collected over a period of 5 weeks (n = 436) to measure if any change had occurred in response times.ResultResponse times appear to follow a Poisson like distribution curve. The average referral was responded to within 6 minutes (n = 1577) prior to the nudge, and 6 minutes (n = 88) after. Prior to the nudge the 95% referral envelope fell within 134 minutes (n = 9728) and was 122 minutes (n = 414) after the intervention. Significant statistical difference is observed upon considering response in the first 240 minutes.ConclusionNudge interventions could be a useful resource-sparing method to improve services. The average referral to the HUH liaison team was quickly responded to within 6 minutes and yet hitting the 1 hour 95% target appears ever-elusive. Hitting targets of 95% responses within 1 hour may prove very difficult if we are not considering natural distributions, such as Poisson, occuring in the backgroung which ultimately may require a change in approaches to how we set performance targets.
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Perryman, Carol. "Assessment Related Skills and Knowledge Are Increasingly Mentioned in Library Job Postings." Evidence Based Library and Information Practice 10, no. 1 (March 6, 2015): 98. http://dx.doi.org/10.18438/b8060t.
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A Review of:
Passoneau, S., & Erickson, S. (2014). Core competencies for assessment in libraries: A review and analysis of job postings. Library Leadership & Management, 28(4):1-19. https://journals.tdl.org/llm/index.php/llm/article/view/7080
Abstract
Objective – The authors sought to determine whether existing definitions of assessment agree with assessment-related skills sought in job postings, and to identify key assessment-related skills, needs for training, and trends in assessment.
Design – Content analysis.
Setting – Job postings from six library-specific websites: the American Library Association, the Library & Information Technology Association, the Society of American Archivists, the Council on Library and Information Resources, the Association of Research Libraries, and Library Assessment job announcements at http://libraryassessment.info/?cat=13.
Subjects – Job titles and descriptions published during an 18-month period between Summer 2012 and Winter 2013 that met the inclusion criteria (n=231).
Methods – Job postings were searched and analyzed in two separate sets whose inclusion criteria is as follows: First, job postings with the term assessment in the position title or as the main focus of the position (n=44) were retrieved; of these, three postings were too old to contain descriptions, so were excluded from analysis. Second, job postings were retrieved with the terms assessment, evaluation, metrics, and strategic in the descriptive text of postings with position titles that did not specifically mention assessment (n=187). The full text of both sets was downloaded to ATLAS.ti software for analysis using a grounded theory approach. Mutually exclusive terms emerging from the coding process were documented and defined; from this analysis, networks of code “families” or co-relational groupings helped to create categories and sub-categories. The context of terms was closely examined to understand the meaning of assessment-related terms in job descriptions. Following this step, Microsoft Excel was used to generate tables and pivot tables, aiding understanding and illustrating data.
Main Results – All 44 job posts containing the term assessment as part of the position title were from research universities or four year colleges; of these, most were ARL member libraries. For these postings, the concept of assessment was more clearly aligned with definitions of assessment as an ongoing process. The positions described, requiring a minimum of three years’ of experience, ranged from entry-level to administrative in nature.
In the second set (187 postings), the interchangeable use of the terms “assessment” and “evaluation” was particularly evident in job postings unrelated to library instruction. No library types other than academic were recruiting for assessment librarians, but related skills, usually referred to as evaluation in public and special libraries, were mentioned in all areas of library practice including instruction, administration, public services, user behavior, and to a lesser extent, access services, archives, information technology, cataloging, and more. While less prominent, these less often mentioned areas of practice also appear to be increasing their awareness of assessment.
Key skills and knowledge areas needed for assessment in libraries emerged from content analysis of the job postings. These were grouped under eight main areas of competency and were augmented by the authors’ own experiences as assessment librarians: background in library assessment, research methods, statistical and analytic skills, visualization and presentation skills, and project management and people skills.
Conclusions – Based upon analysis of this set of documents, a culture of assessment in libraries appears to be emerging, demonstrating a possible upward trend when contrasted with the earlier research of Walter and Oakleaf (2010). Overall, assessment related skills and knowledge were increasingly evident across all library types and positions. Suggestions for aiding the development of an emerging culture of assessment include fostering liaisons between ALA divisions and library schools to persuade the schools of the need for related coursework, workshops focused on assessment-related skills, certification programs, and a proposed minor in library assessment. Opening avenues for discussion between library types could enhance the growth of an assessment culture beyond academic librarianship. Additional research to better understand the diffusion of assessment culture and practice into non-academic libraries is also recommended.
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Malik, M. F. A., and B. Najeeb. "Retrospective Chart Review of Patients with Self-Harm Seen as Liaison Psychiatry in Pakistan." European Psychiatry 65, S1 (June 2022): S251. http://dx.doi.org/10.1192/j.eurpsy.2022.647.
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Introduction Self‑harm is an ‘act of self‑poisoning or self‑injury carried out by a person, irrespective of their motivation’. A history of self-harm is linked with suicide risk. A study in Pakistan found self-harm to be more common in young people with unemployment and interpersonal difficulties as common triggers. Expanding liaison psychiatry services leads to an earlier assessment of patients with self-harm. Objectives To study the demographic and clinical variables of patients along with methods and precipitating factors of self-harm. Methods A retrospective chart review of patients presenting with self-harm seen as a part of liaison psychiatry from October 2018 to June 2021. Results A total of 168 cases were seen of which 10 were excluded due to incomplete data. Of 158 cases gender split was roughly in the middle, with 49.4% males (n=78) and 50.6% females (n=80). The mean age of patients was 27.59 with a range of 12-70, 40.5% belonged to the age group of 20-29 (n=64) (Figure 1). 77.8% (n=123) had a past psychiatric history. The most common being depressive disorder 31.6% (n=50) and borderline personality disorder 30.4% (n=48). 35.4% of patients reportedly had previous attempts of self-harm. The most common methods being the use of sharp objects, rat-pill poisoning, and corrosive intake (Figure 2). Conflicts with family and relationship difficulties were reported to be the most common precipitating factors. Conclusions Self-harm is a challenging and frequent presentation. Patients may present with diverse characteristics and varying needs. Hence physicians must be prepared for timely liaison and prompt management. Disclosure No significant relationships.
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Iqbal, Yousaf, Peter Haddad, Javed Latoo, Majid Alabdulla, Sultan Albrahim, Rajeev Kumar, and Ovais Wadoo. "Psychiatric presentations of patients with COVID-19: a retrospective review of 100 consecutive patients seen by liaison psychiatry services." BJPsych Open 7, S1 (June 2021): S257—S258. http://dx.doi.org/10.1192/bjo.2021.688.
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AimsCoronavirus disease 2019 (COVID-19) is associated with higher rates of psychiatric morbidity due to various factors, including quarantine, social isolation, stigma, financial difficulties and direct and indirect central nervous system impact of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2).This study aimed to describe the psychiatric morbidity of patients with COVID-19 referred to liaison psychiatry services in Qatar.MethodThis study was a retrospective review of patient records of the first 100 consecutive SARS-Cov-2 positive patients referred to liaison psychiatry services. The study was approved by the Hamad Medical Corporation Institutional Review Board (IRB) (MRC-05–072). Data were analysed using descriptive statistics.ResultThe majority (n = 92) of 100 included patients were male and median age was 43 years. Patients were of diverse background with majority of South Asian (Indian, Pakistani, Bengali, Nepalese, and Afghan) (n = 60), followed by Qatari (n = 18) background. Mean length of hospital stay was 26.51 days.35 patients had severe or critical COVID-19 pneumonia, and 67 had at least one underlying physical comorbidity. Significant psychosocial stressors other than positive SARS-Cov-2 status, including lockdown, quarantine, finances and relationships issues were identified in 48 patients.A total of 35 patients had a positive past psychiatric history, out of which 17 were on maintenance psychotropic medications. Insomnia was the commonest psychiatric symptom (n = 65), followed by anxiety (n = 52), agitation (n = 42), depression (n = 39), changes in appetite (n = 32) and irritability (n = 30). The principal psychiatric diagnoses made were delirium (n = 29), acute stress reaction or adjustment disorder (n = 25), depression (n = 16), mania (n = 15), anxiety (n = 14), non-affective psychosis (n = 13), and dementia (n = 6). Approximately half of the patients with mania or non-affective psychosis had it as their first-onset disorder.ConclusionSARS-CoV-2, in both symptomatic and asymptomatic patients, is associated with a wide range of psychiatric morbidity which emphasizes clinicians’ vigilance for psychiatric symptoms. Insomnia was the commonest neuropsychiatric symptom which may have clinical practice and potential preventive strategies implications.Delirium, the commonest diagnosis in the study carries high morbidity and mortality and may reflect SARS-Cov-2 propensity to affect the brain directly and indirectly through a cytokine storm, organ failure, and prothrombotic state. Patients can also present with new-onset mania or non-affective psychosis. It is noteworthy that about two-thirds of the patients had no past psychiatric history.This study, along with expanding body of evidence may assist with resource allocation and liaison psychiatry services planning. It also underscores the importance of designing future studies to better understand longer-term psychiatric sequelae of COVID-19.
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Coary, Roisin, Kathryn McCarthy, Haytham Sumrien, and David Shipway. "156 Review of Outcomes of a Dedicated Geriatric Surgical Liaison Service." Age and Ageing 48, Supplement_3 (September 2019): iii17—iii65. http://dx.doi.org/10.1093/ageing/afz103.91.
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Abstract Background In the United Kingdom, the 2010 National Confidential Enquiry into Patient Outcome and Death report ‘An Age Old Problem’ outlined significant shortcomings in the perioperative care of older people. Other than hip fractures, the care of older patients under surgical specialities is largely devoid of routine geriatrician input. In August 2018, we introduced daily geriatric reviews (GR) on the gastrointestinal surgical wards, aiming to improve length of stay (LOS) and mortality. Methods All acute general surgery admissions for patients ≥70 years were reviewed between September and October 2017 (pre-introduction) and 2018 (post-introduction), and outcomes compared. For 2018, comparisons were also made between those who had GR and those who didn’t. Results There were 173 admissions in 2017, vs 190 in 2018. In both 2017 and 2018, median age was 80, median LOS was 4 days, and clinical frailty scale (CFS) 4. Twenty-two percent (38/173) of patients had a surgical procedure in 2017, vs 33% (63/190) in 2018. Inpatient mortality was 8% (13/173) in 2017 (median CFS 6), vs 6% (11/190) in 2018 (median CFS 6). In 2018, 21% (40/190) of patients had GR: median time to review 3 days. 54% (n=22) of the patients with GR underwent a surgical procedure, 37% (n=15) were admitted to ICU, and inpatient mortality was 5% (n=2), vs 28% (n=42), 4% (n=6) and 6% (n=9) respectively for those without GR. 30 day readmission for those with GR was 12.5% (n=5), vs 18.4% (n=28) for those not seen. Conclusion While more surgical procedures were performed in 2018 (post-introduction), overall LOS remained unchanged and improved mortality was observed compared to 2017. Geriatricians are seeing more post-operative and ICU patients, and despite presumed increased complexity, both mortality and readmission rates remain low. Screening for frailty and specific inclusion criteria may improve rates of GR.
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Zito, Ester, and Ana Ferreiro. "Calcium and Redox Liaison: A Key Role of Selenoprotein N in Skeletal Muscle." Cells 10, no. 5 (May 6, 2021): 1116. http://dx.doi.org/10.3390/cells10051116.
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Selenoprotein N (SEPN1) is a type II glycoprotein of the endoplasmic reticulum (ER) that senses calcium levels to tune the activity of the sarcoplasmic reticulum calcium pump (SERCA pump) through a redox-mediated mechanism, modulating ER calcium homeostasis. In SEPN1-depleted muscles, altered ER calcium homeostasis triggers ER stress, which induces CHOP-mediated malfunction, altering excitation–contraction coupling. SEPN1 is localized in a region of the ER where the latter is in close contact with mitochondria, i.e., the mitochondria-associated membranes (MAM), which are important for calcium mobilization from the ER to mitochondria. Accordingly, SEPN1-depleted models have impairment of both ER and mitochondria calcium regulation and ATP production. SEPN1-related myopathy (SEPN1-RM) is an inherited congenital muscle disease due to SEPN1 loss of function, whose main histopathological features are minicores, i.e., areas of mitochondria depletion and sarcomere disorganization in muscle fibers. SEPN1-RM presents with weakness involving predominantly axial and diaphragmatic muscles. Since there is currently no disease-modifying drug to treat this myopathy, analysis of SEPN1 function in parallel with that of the muscle phenotype in SEPN1 loss of function models should help in understanding the pathogenic basis of the disease and possibly point to novel drugs for therapy. The present essay recapitulates the novel biological findings on SEPN1 and how these reconcile with the muscle and bioenergetics phenotype of SEPN1-related myopathy.
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MacGregor, Stephen, and Amanda Cooper. "Blending Research, Journalism, and Community Expertise: A Case Study of Coproduction in Research Communication." Science Communication 42, no. 3 (May 28, 2020): 340–68. http://dx.doi.org/10.1177/1075547020927032.
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The patterns of practice characterizing coproduction as an approach to research communication are explored through semistructured interviews with researchers ( N = 6), journalists ( N = 6), a community liaison ( N = 1), and editorial staff ( N = 2) who participated in the coproduction of podcasts. Despite various challenges encountered by participants, coproduction was a primarily positive experience that motivated the reexamination of taken-for-granted perceptions about each stakeholder’s role in research communication. Key questions are raised for future research about coproduction in research communication as well as suggestions for stakeholders planning or engaging in coproduction.
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Deshpande, Neeraj, Naveen S. Yadav, Vrinda Saxena, Raghavendra Reddy, and Suresh Kumar Kovvuru. "Alliance of Oral Hygiene Practices and Abrasion among Urban and Rural Residents of Central India." Journal of Contemporary Dental Practice 13, no. 1 (2012): 55–60. http://dx.doi.org/10.5005/jp-journals-10024-1095.
Повний текст джерелаАнотація:
ABSTRACT Objectives To attain alliance between the oral hygiene practices with prevalence of tooth abrasion among urban and rural adult population of Central India. To plan dental care services in inaccessible areas and to suggest appropriate remedial measures to prevent this avertable and self-inflicted injury of teeth in this cross-sectional study. Materials and methods A sum of 1045 adult residents both from Urban (529) and rural (516) parts of Bhopal district (Central India) was selected on a random basis. The multistage sampling technique was adopted to ascertain the sample size. In urban area the study population consisted of 240 males, 289 females and 201 males and 315 females in rural area respectively. All residents above 18 years of age from the Bhopal district were included in cross-sectional study. Assessment form comprises of questionnaire and general information on oral hygiene practices, dietary habits and medical history. Abrasion was assessed using diagnostic criteria recommended by Smith and Knight (modified). Chi- square test was used to test associations between categorical variables at 5% level of significance. Regression analysis attempted to define for risk factors causing abrasion. Literature on the prevalence of abrasion is very sparse, so attempt is made to correlate the etiological factors and recommend to prevent tooth wear. Results Investigation of this cross-sectional study was aggregate of 1045 residences. Result shows high prevalence of abrasion 70.2%. Higher prevalence concomitant with diffident habits related to oral hygiene maintenance was recorded more among rural (76.9%) when compared to urban dwellers (63.7%). Presence of abrasion verifies statistical significance in relation to age, ruralurban difference and variations in habit of oral hygiene care. Stated in the present study, avertable and self-inflicted is toothabrasion, recurrently resulted by the reprehensible brushing method and common use of indigenous material for the maintenance of oral hygiene. Conclusion Shows significant liaisons with the presence of abrasions in relation to Urban and rural dwelling, age, material used and mode of brushing and duration of brushing. Indigenous and course material causes high amount of enamel wear and with the advancement in age abrasion tend to increase. Prevalence of abrasion does not show any gender predilection. Cultural believes, lifestyle and transition reflects in deviating presence of abrasion in populations. How to cite this article Yadav NS, Saxena V, Reddy R, Deshpande N, Deshpande A, Kovvuru SK. Alliance of Oral Hygiene Practices and Abrasion Among Urban and Rural Residents of Central India. J Contemp Dent Pract 2012;13(1): 55-60.
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Morris, Eric, Catie Harris, and Lynley Nolan. "First psychosis liaison unit family education programme." Psychiatric Bulletin 23, no. 4 (April 1999): 212–14. http://dx.doi.org/10.1192/pb.23.4.212.
Повний текст джерелаАнотація:
Aims and methodsThis study presents an evaluation of an education programme for families whose relative has experienced a first episode of psychosis. Participants attended a five-week programme and were asked to rate their level of knowledge and confidence in managing the illness before and after the education sessions.ResultsTwo consecutive groups of relatives (n=9; n=11) attended the programme. Comparison of knowledge and confidence ratings before and after the education sessions demonstrated significant levels of change at the final session for both groups.Clinical ImplicationsEducation for relatives of people experiencing psychosis for the first time is an important component in community management. Such education improves the knowledge and confidence of relatives in coping with the illness, possibly leading to a more accepting and less stressful family environment reducing the risk of relapse and promoting the psychological health of the patient.
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Azvee, Z., I. Khair, N. Barry, and J. Sheehan. "4Ds: Documenting delirium diagnosis in discharge summary." European Psychiatry 64, S1 (April 2021): S499—S500. http://dx.doi.org/10.1192/j.eurpsy.2021.1336.
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IntroductionHospital discharge is a significant transitional phase with varying levels of needs and risks to be managed as lapses in communication commonly happen between secondary/tertiary and primary care.ObjectivesOur aim was to look at inclusion of delirium diagnosis in discharge summaries based on standards set by: 1. Health Information and Quality Authority (HIQA) National Standard for Patient Discharge Summary Information 2. NICE Guidelines on Delirium: prevention, diagnosis and management (CG 103)MethodsAll inpatients referred to Liaison Psychiatry from 9thJuly 2019 till 5th January 2020 were included, n = 729. Compared discharge summaries diagnoses to the internal Liaison Psychiatry ICD 10 consensus diagnosis and also HIPE coded diagnosis specifically for delirium.ResultsDelirium diagnoses and inclusion of delirium-specific information on discharge summarynProportion (n=112*) (%)Q1 Any F05 diagnosis coded by Liaison Psychiatry117100Q2 F10.4 diagnosis coded by Liaison Psychiatry00Q3 F1x.4 diagnosis coded by Liaison Psychiatry00Q4 Any F05, F10.4 and F1x.4 diagnosis coded in discharge summary on patient centre2320.5Q5 Was the word delirium or its synonym such as acute confusional state mentioned in the body of the discharge summary?6255.4HIPE Code Diagnosis6658.9ConclusionsHospital discharge summaries are essentially the main communication link between hospitalists and general practitioners to ensure continuity and future care of patients. Delirium diagnosis is not always recorded in discharge summaries. This is a risk to be managed. Education is vital to ensure awareness, prevention, early recognition and to ensure recording of diagnosis of delirium.
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Puthenpurakal, Tony J. "A function on the set of isomorphism classes in the stable category of maximal Cohen-Macaulay modules over a Gorenstein ring: with applications to liaison theory." MATHEMATICA SCANDINAVICA 120, no. 2 (May 27, 2017): 161. http://dx.doi.org/10.7146/math.scand.a-25728.
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Let $(A,\mathfrak{m})$ be a Gorenstein local ring of dimension $d \geq 1$. Let $\operatorname{\underline{CM}}(A)$ be the stable category of maximal Cohen-Macauley $A$-modules and let $\operatorname{\underline{ICM}}(A)$ denote the set of isomorphism classes in $\operatorname{\underline{CM}}(A)$. We define a function $\xi \colon \operatorname{\underline{ICM}}(A) \to \mathbb{Z}$ which behaves well with respect to exact triangles in $\operatorname{\underline{CM}}(A)$. We then apply this to (Gorenstein) liaison theory. We prove that if $\dim A \geq 2$ and $A$ is not regular then the even liaison classes of $\{\,\mathfrak{m}^n \mid n\geq 1 \,\}$ is an infinite set. We also prove that if $A$ is Henselian with finite representation type with $A/\mathfrak{m}$ uncountable then for each $m \geq 1$ the set $\mathcal {C}_m = \{\, I \mid I \text { is a codim $2$ CM-ideal with } e_0(A/I) \leq m \,\}$ is contained in finitely many even liaison classes $L_1,\dots ,L_r$ (here $r$ may depend on $m$).
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Fossey, Matt, Lauren Godier-McBard, Elspeth A. Guthrie, Jenny Hewison, Peter Trigwell, Chris J. Smith, and Allan O. House. "Understanding liaison psychiatry commissioning: an observational study." Mental Health Review Journal 25, no. 4 (September 21, 2020): 301–16. http://dx.doi.org/10.1108/mhrj-03-2020-0016.
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Purpose The purpose of this paper is to explore the challenges that are experienced by staff responsible for commissioning liaison psychiatry services and to establish if these are shared by other health professionals. Design/methodology/approach Using a mixed-methods design, the findings from a mental health commissioner workshop (n = 12) were used to construct a survey that was distributed to health care professionals using an opportunistic framework (n = 98). Findings Four key themes emerged from the workshop, which was tested using the survey. The importance of secure funding; a better understanding of health care systems and pathways; partnership working and co-production and; access to mental health clinical information in general hospitals. There was broad convergence between commissioners, mental health clinicians and managers, except in relation to gathering and sharing of data. This suggests that poor communication between professionals is of concern. Research limitations/implications There were a small number of survey respondents (n = 98). The sampling used an opportunistic framework that targeted commissioner and clinician forums. Using an opportunistic framework, the sample may not be representative. Additionally, multiple pairwise comparisons were conducted during the analysis of the survey responses, increasing the risk that significant results were found by chance. Practical implications A number of steps were identified that could be applied in practice. These mainly related to the importance of collecting and communicating data and co-production with commissioners in the design, development and monitoring of liaison psychiatry services. Originality/value This is the first study that has specifically considered the challenges associated with the commissioning of liaison psychiatry services.
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Coary, Roisin, Kath Jenkins, Emma Mitchell, Anne Pullyblank, and David Shipway. "61 Impact of Dedicated Geriatrician Involvement on National Emergency Laparotomy Audit Standards and Outcomes." Age and Ageing 48, Supplement_3 (September 2019): iii1—iii16. http://dx.doi.org/10.1093/ageing/afz102.12.
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Abstract Background Older patients undergoing emergency laparotomy (EmLap) have high levels of mortality and morbidity. The National Emergency Laparotomy Audit (NELA) in the United Kingdom records processes and outcome measures for patients undergoing EmLap. Recent data shows that geriatrician review is associated with reduced post-surgical mortality (Oliver C.M. et al., British Journal of Anaesthesia 2018). Geriatrician review of all patients aged ≥70 years is a NELA standard. However, the most recent national report shows only 23% compliance, falling short of the target of 80% and consistently the poorest performing standard. Methods In August 2018, we established a dedicated gastrointestinal surgery liaison service to replace ad hoc geriatrician reviews. We evaluated the impact on NELA standard compliance and patient outcomes. Data were extracted from the local NELA database on all patients aged ≥70 years, for the first six months of the service (September to February). These were compared to the same time period in the preceding year prior to service launch. Results Following service introduction, increased numbers of patients aged ≥70 years underwent EmLap: 50 (2018-9) vs 31 (2017-8). Geriatrician review occurred in 86% (n=43) in 2018-9, compared to 16% (n=5) in 2017-8. Inpatient mortality fell from 23% (n=7) in 2017-8 to 14% (n=7) in 2018-9. Discharge to own home rose to 76% (n=38) in 2018-9 from 68% (n=21) in 2017-8. One patient in each cohort was newly discharged to a nursing home. Mean length of stay was 17.9 days in 2018-9 (range 3-75), versus 17.6 in 2017-8 (range 3-94). Conclusion Introduction of a dedicated geriatric surgical liaison service is associated with increased compliance with NELA standards. Despite more emergency laparotomies being performed on older patients, this was associated with improved mortality and rates of home discharge, consistent with published data. Targeted investment in surgical liaison services may therefore be warranted.
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Theochari, A., O. Mouzas, and N. Angelopoulos. "P01-404-Differences in hospitals create different models of functioning in consultation-liaison service." European Psychiatry 26, S2 (March 2011): 407. http://dx.doi.org/10.1016/s0924-9338(11)72115-0.
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The aim of this study is to investigate differences in Consultation-Liaison (C-L) service between two General Hospitals in Greece in order to provide better health services to our patients.We try to examine referral causes from C-L Psychiatry Unit of an urban General hospital (G.H.) and a local University hospital (U.H.) and find out potential differences. 492 data were gathered (G.H = 96 U.H. = 396) within a 6 months period.Most liaison referrals (n = 260, 52,8%) were of Internal Medicine Units. The bulk of referrals were either drug adjustment (n = 157 31,9%) or suicide attempts (n = 122 24,8%). According to our findings the vast majority were diagnosed of depression (n = 67 22,9%) or delirium. 153 patients had Psychiatric history and in 86 of them (56,2%) we were called for help with their drug therapy (rearranging drug doses or preventing side effects with recent medication). 71 patients although were found of no psychiatric problem and cause of referral were management behavioral problems, such as patients negation or irritation.Both hospitals found out of similar needs in most examined elements. C-L service is the link between psychological process and physical illness. Further research in sociodemographic characteristics and cause of referrals in different kind of Hospitals may enlighten the needs of C-L service in each case.
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Ballico, Edoardo, Giorgio Bolondi, and Juan Carlos Migliore. "The Lazarsfeld-Rao Problem for Liaison Classes of Two-Codimensional Subschemes of P n." American Journal of Mathematics 113, no. 1 (February 1991): 117. http://dx.doi.org/10.2307/2374823.
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Graton, Jérôme, François Besseau, Michel Berthelot, Ewa D. Raczynska, and Christian Laurence. "L'échelle pKHB de basicité de liaison hydrogène des amines tertiaires aliphatiques." Canadian Journal of Chemistry 80, no. 10 (October 1, 2002): 1375–85. http://dx.doi.org/10.1139/v02-176.
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The hydrogen bond acceptor strength of 40 tertiary amines has been measured by Fourier transform infrared (FTIR) spectrometry from their 1:1 complexation constant towards 4-fluorophenol in CCl4 at 25°C (the pKHB scale). Also measured was the frequency shift, Δν(OH), of the ν(OH) band of methanol hydrogen-bonded to these amines. The comparison of the thermodynamic hydrogen bond basicity scale, pKHB, with the spectroscopic one, Δν(OH), and with the Brønsted pKa scale, points to the great sensitivity of pKHB to steric effects. The pKHB scale of tertiary amines extends from 2.71 for quinuclidine to 0.34 for N,N-diisopropyl-3-pentylamine. The main factors governing this important variation (17 kJ·mol1 on the Gibbs energy scale) are the electron-withdrawing inductive effect and various kinds of steric effects (e.g., opening of the CNC angles and hindrance to OH fixation on the nitrogen lone pair). Infrared (IR) spectra show the attachment of 4-fluorophenol to the nitrile nitrogen of Me2NCH2C[Formula: see text]N and Me2NCH2CH2C[Formula: see text]N, to the oxygen of N-methylmorpholine, and to the π electrons of (HC[Formula: see text]CCH2)3N and (PhCH2)3N, in addition to the attachment to the amino nitrogen. In (PhCH2)3N, the electron-withdrawing effect of the three benzyl substituents and, mainly, the very important congestion of the nitrogen lone pair reduce the nitrogen hydrogen-bond basicity almost to nothing, so that tribenzylamine, a nitrogen Brønsted base, turns to a π base in hydrogen bonding. From this example, the large differences between the pKHB and pKa scales of organic bases are emphasized.Key words: basicity, hydrogen bonding, tertiary amines, pKHB scale.
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Splendido, Frida. "The development of obligatory liaison in early L2 learners of French." French liaison in second language acquisition / La liaison en français langue étrangère 10, no. 1 (2019): 71–95. http://dx.doi.org/10.1075/lia.17024.spl.
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AbstractStudies on the acquisition of Frenchliaisonhave primarily focused on monolingual children or adult second language (L2) learners in a university context. To bridge the gap between these two populations, the present article focuses on child L2 (cL2) learners – a particularly interesting group, since they are L2 learners who, unlike adults, do not have access to writing. How doesliaisondevelop in cL2 French? Is the development more similar to L1 or L2 acquisition? These questions are explored through longitudinal data from cL2 learners (age of onset: 3;0–3;5,n = 3), with monolingual (n = 2) and bilingual (n = 3) L1 controls. The cL2 data present certain similarities with adult L2 learners, but also with L1 controls. However, productions vary greatly within the L2 group: whereas one of the three learners shows clear development over time, behaving similarly to the L1 children at the end of the observation period, another learner hardly produces anyliaisonsat all.
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Meyer, Claudia, Emma Renehan, Frances Batchelor, Catherine Said, Terry Haines, Rohan Elliott, and Dianne Goeman. "‘Falls not a priority’: insights on discharging older people, admitted to hospital for a fall, back to the community." Australian Journal of Primary Health 24, no. 1 (2018): 66. http://dx.doi.org/10.1071/py17052.
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Falls are common among older people and a leading cause of injury-related hospitalisation. The immediate post-hospitalisation period is a risky time for further falls. This paper explores discharge strategies from the perspectives of older people hospitalised for a fall and liaison nurses assisting people to return home. Exploratory mixed methods were used. Semi-structured interviews with older people were conducted regarding their experience of the fall and discharge strategies. Quality of life, falls risk and functional capacity were measured by questionnaire. Liaison nurses were also interviewed. Interviews were audio-recorded, transcribed and thematically analysed. Mixed-method synthesis occurred using role-ordered matrix analysis. Older people (n = 13) and liaison nurses (n = 6) participated. Older persons’ quality of life was average and falls risk high. Thematic analysis revealed three key themes: ‘falls are not a priority’, ‘information not given, or given and not retained’ and ‘reduction in confidence and independence’. Role-ordered matrix analysis identified differences between acute and rehabilitative hospital stays. Older people hospitalised for a fall present a unique opportunity for implementation of falls prevention strategies. However, hospitalisation is often a time of crisis with competing priorities. Timing and relevance are crucial for optimal uptake of falls prevention strategies, with the primary care setting well-placed for their implementation.
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Carr, Vaughan J., Terry J. Lewin, Jane M. Walton, Catherine Faehrmann, and Alexander L. A. Reid. "Consultation—Liaison Psychiatry in General Practice." Australian & New Zealand Journal of Psychiatry 31, no. 1 (February 1997): 85–94. http://dx.doi.org/10.3109/00048679709073804.
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Objective:This paper describes the characteristics of 303 consecutive referrals, over a 12-month period, to a consultation—liaison (C—L) psychiatry service provided to eight group general practices in Newcastle, Australia. Method:A purpose designed service audit form was used throughout the evaluation period to collect information about demographic characteristics, reasons for referral, service contacts, psychiatric diagnoses and clinical management. In addition, patients were invited to participate in a separate, prospective outcome evaluation study, which involved structured interviews and questionnaires. Results:The most common reasons for referral were: depression (33%); anxiety (12%); diagnostic assessment (9%); and impaired relationships (8%). The most common psychiatric diagnoses were: mood disorders (29%); mild, transient conditions (29%); anxiety (14%); and substance abuse disorders (12%). Following the psychiatric consultation(s), GPs were actively involved in patients’ treatment in 53% of cases. However, there was a higher than expected rate of referral (44%) to another mental health agency. Selected comparisons are also reported between patients referred to the C—L service (n = 303) and a sample of non-referred GP attenders (n = 535). Conclusions:As expected, the diagnostic profiles of patients attending the C—L service differed in several respects from those using similar services in general hospitals. There were comparatively low rates of organic brain syndromes, suicide risk evaluations, and problems of differential diagnosis of somatic symptoms. Greater emphasis needs to be placed on more formal psychiatric education for GPs, on ways of screening out from the referral process those patients with mild, transient conditions who do not require specialist expertise, and on the development of strategies to help GPs manage such conditions.
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Samir Labib Mishriky, Raafat, and Majid Al Abdulla. "OLD AGE LIAISON MENTAL HEALTH SERVICEIN QATAR INTERVENTIONS AND OUTCOMES." International Journal of Advanced Research 11, no. 08 (August 31, 2023): 865–72. http://dx.doi.org/10.21474/ijar01/17463.
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Background: There is wide variation in the degree of provision of liaison mental health services across many countries (3) Qatar is no exception, in a general hospital in southern part of Qatar, Liaison Old Age Mental health is provided by Adult Psychiatrists with a phone advise from an Old Age Psychiatrist when requested. A general Hospital in the Northern division of the country is provided by Adult Psychiatrists with one day input from an old age Psychiatrist. Older adults Patients with mental health problems using acute and general hospital inpatient services should have access to a liaison service that specializes in the diagnosis and management of older peoples mental health (5) The research represents a newold age liaison psychiatry service intervention and outcomes in the state of Qatar. Methods: We audited the number referrals to Old Age Mental Health Liaison one year before a new service intervention in a central General hospital and one year after the service intervention. All referrals are received by the Liaison coordination office in the General hospital and data was collected electronically from the office to ensure accuracy. We also audited the educational interventions done for both staff and patients/Families.Our study included all the number of referrals for patients aged 65 plus and under 65 with Dementia to ensure the maximum statistical power possible for the service intervention. Results: The total number of referrals for patients aged 65 and above or below 65 with Dementia from June 2021 to May 2022 were 125 (n=125). The total number of Old Age Liaison Similar referrals after the service intervention from June 2022 to May 2023 were 95 referrals (n=95, p 0.01, 24% reduction in referrals rates)The Chi squared test was used to calculate the p value. Expected average of referrals to a general hospital was estimated from several inner cities general hospitals (8,21) Conclusion: The authors believe that is the first service to focus on Old Age Mental Health Liaison in the state Qatar. The study was statistically significant and qualitatively included educational outcomes provided for both staff and Patients/families. In addition, it showed an overall reduction in the number of referrals following our intervention. We believe that our outcomes are evidence based and although our outcomes are limited, they are specific, measurable, attainable, and time linked.
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Pomino, Natascha, and Elisabeth Stark. "Proper name-marking via liaison in French." STUF - Language Typology and Universals 72, no. 4 (November 26, 2019): 627–52. http://dx.doi.org/10.1515/stuf-2019-0024.
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Abstract The liaison consonant [z] in French noun phrases has traditionally been assumed to function as a plural marker. The realization of “plural [z]” in N(oun)-A(djective)-combinations is becoming, however, very rare in naturalistic data – except for contexts which allow a proper-name reading. On the one hand, one might think that we are dealing with a recent phenomenon, the beginning of a potential linguistic change in French in the sense of exaptation, reuse of former morphophonological material such as plural markers to signal proper-namehood in the sense of ‘frozen morphology’. If this turns out correct, we expect the productivity of the new synchronic function to increase: New NA-combinations which function as proper names should be realized systematically with liaison, and proper name-marking via liaison should also become possible with other liaison consonants. On the other hand, we may be dealing with a (completed) diachronic process, in that only those NA-combinations which allowed liaison at the relevant point in time may have a liaison consonant in their univerbalized form. That is, new NA-combinations, even though they are used as proper names, do not display a liaison consonant, because liaison is no longer possible. The purpose of this paper was to investigate, based on empirical studies, whether liaison productively marks NA-combinations which function as proper names and distinguishes them from NA-combinations that count as common nouns, or whether we are dealing with a completed diachronic process. In view of the poor productivity observed, we argue that we are dealing with cases of univerbation.
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Ben Haj Amara, A., J. Ben Brahim, G. Besson, and C. H. Pons. "Etude d'une nacrite intercalée par du dimethylsulfoxide et n-methylacetamide." Clay Minerals 30, no. 4 (December 1995): 295–306. http://dx.doi.org/10.1180/claymin.1995.030.4.03.
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ResumeUne nacrite est intercalée par deux composés organiques polaires: le diméthylsulfoxide (DMSO) et le n-méthylacétamide (NMA). Les deux solvants ont des moments dipolaires très voisins (4 debyes) mais des constantes diélectriques différentes (49 pour le DMSO et 179 pour le NMA). L'intercalation du NMA est plus rapide que celle du DMSO. Les deux complexes homogènes obtenus sont étudiés par diffraction des rayons X, spectroscopie infrarouge et ATD. L'étude par spectroscopie IR a montré que la nacrite expansée par du DMSO se comporte comme la kaolinite expansée par le même solvant. Dans le cas de la nacrite intercalée par du NMA, trois nouvelles bandes d'absorption dues aux vibrations de valence des OH liés par pont hydrogène avec le groupement C=O et situées respectivement à 3500, 3543 et 3589 cm−1 apparaissent. La fréquence v(N-H) du NMA est intermédiaire entre celles du liquide et d'une solution diluée, indiquant une liaison par pont hydrogène probablement avec les oxygènes de la couche tétraédrique du silicate. La diffraction des rayons X sur des échantillons orientés nous a permis d'obtenir 13 réflexions 00l pour chaque complexe. Une étude quantitative, par transformée de Fourier monodimensionnelle dans la direction perpendiculaire au plan du feuillet, a permis de déterminer le nombre de molécules organiques intercalées (une molécule par Si2Al2O5(OH)4) et leur orientation dans l'espace interlamellaire. L'ATD a montré par ailleurs que le complexe Nac.DMSO est plus stable que le complexe Nac.NMA.
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Anderson, Daniel, Howard Cattell, and Elaine Bentley. "Nurse-led liaison psychiatry service for older adults: service evaluation." Psychiatric Bulletin 32, no. 8 (August 2008): 298–302. http://dx.doi.org/10.1192/pb.bp.107.016725.
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Aims and MethodTo comprehensively describe a nurse-led consultation liaison service for older adults by retrospectively reviewing all referrals received in 2006 and comparing them against other services and benchmark reports.ResultsOf the 298 individuals referred to psychiatric services from other hospital wards, 120 were aged 85–94 years old (40%), 193 were male (65%) and 152 were referred from geriatrics (51%). A majority of 204 have not had previous contact with psychiatric services (69%). the most common diagnosis was dementia (33%, n=88), with 27% individuals (n=65) being referred onwards to secondary care.Clinical ImplicationsThis nurse-led service, using a novel approach of a support worker providing further community support, functions well compared with traditional consultation models. It helps identify many individuals with dementia and engages them into community psychiatric services.
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Cossery, J. M., C. Perdicakis, G. Coudert, G. Guillaumet, and L. Pichat. "Isosteres Oxygenes d'Hydroxy-di-n-Propylaminotetralines Syntheses de Monomethoxy et Monohydroxy- (DI-N-Propylamino)-3 Chromannes [n-Propyl-3H] Racemiques: Nouveaux Radioligands des Sites de Liaison Serotoninergiques 5-HT1a et Dopaminergiques D2." Journal of Labelled Compounds and Radiopharmaceuticals 25, no. 8 (August 1988): 833–54. http://dx.doi.org/10.1002/jlcr.2580250805.
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