Дисертації з теми "Lateral lymph node dissection"
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Hassan, Hakki. "Morbidity of mediastinal lymph node dissection VS sampling treatment of lung cancer /." Bern : [s.n.], 1999. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Повний текст джерелаNini, Alessandro [Verfasser]. "The role of lymph node dissection in kidney cancer surgery for staging and therapy / Alessandro Nini." Saarbrücken : Saarländische Universitäts- und Landesbibliothek, 2020. http://d-nb.info/1238074197/34.
Повний текст джерелаOwusu, Miriam Sekyere. "Lymphedema, post breast cancer treatment at Komfo Anokye Teaching Hospital, Kumasi, Ghana." Thesis, Cape Peninsula University of Technology, 2011. http://hdl.handle.net/20.500.11838/2262.
Повний текст джерелаTo determine the incidence, risk factors and the treatment of lymphedema after breast cancer treatment at the oncology unit of KATH, Kumasi, Ghana from 01 January 2005 to 31 December 2008. Descriptive retrospective survey was used. Using a data capture sheet, data was collected from the medical records of the breast cancer patients. Breast cancer and lymphedema-related variables were collected. Data was analyzed as descriptive statistics. Chi-square test was applied to determine whether or not two variables are independent variables. Among 313 patients treated for breast cancer between 2005 and 2008, 31 (9.9%) developed lymphedema after treatment. A chi-square test showed that axillary lymph node dissection was statistically a significant risk factor of lymphedema (Chi-square test value=7.055, P value=0.008). Radiation and late stage of breast cancer diagnosis may have contributed in development of lymphedema despite having P value> 0.05. Age, body mass index (BMI) and hypertension were also not associated with lymphedema.
Nishimura(Tada), Harue. "Risk factors for lower limb lymphedema after lymph node dissection in patients with ovarian and uterine carcinoma." 京都大学 (Kyoto University), 2009. http://hdl.handle.net/2433/126591.
Повний текст джерела0048
新制・論文博士
博士(社会健康医学)
乙第12395号
論社医博第4号
新制||社医||6(附属図書館)
27425
UT51-2009-M901
京都大学大学院医学研究科社会健康医学系専攻
(主査)教授 小西 郁生, 教授 佐藤 俊哉, 教授 鈴木 茂彦
学位規則第4条第2項該当
Vercellino, Giuseppe F. [Verfasser]. "Laparoscopic lymph node dissection should be performed before fertility preserving treatment of patients with cervical cancer / Giuseppe F. Vercellino." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2014. http://d-nb.info/1062949226/34.
Повний текст джерелаVercellino, Giuseppe Filiberto [Verfasser]. "Laparoscopic lymph node dissection should be performed before fertility preserving treatment of patients with cervical cancer / Giuseppe F. Vercellino." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2014. http://d-nb.info/1062949226/34.
Повний текст джерелаvon, Below Catrin. "PET and MRI of Prostate Cancer." Doctoral thesis, Uppsala universitet, Radiologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300940.
Повний текст джерелаMatheus, Carolina Nascimben 1980. "Avaliação do fluxo sanguíneo do membro superior de mulheres submetidas a abordagem axilar para tratamento do câncer de mama : Blood flow in the superior limbs of women with breast cancer undergoing a surgical approach to the axilla." [s.n.], 2015. http://repositorio.unicamp.br/jspui/handle/REPOSIP/312844.
Повний текст джерелаTese (doutorado) - Universidade Estadual de Campinas, Faculdade de Ciências Médicas
Made available in DSpace on 2018-08-27T18:24:57Z (GMT). No. of bitstreams: 1 Matheus_CarolinaNascimben_D.pdf: 2850729 bytes, checksum: fd170a425e039c6e8f1324b637393c8b (MD5) Previous issue date: 2015
Resumo: Objetivo: Esta tese visou avaliar os parâmetros vasculares arteriais e venosos dos vasos axilares e braquiais em mulheres submetidas a tratamento para câncer de mama. Subdividimos estas avaliações conforme os objetivos abordados em duas publicações, respectivamente: 1) Comparar aos parâmetros de circulação venosa e arterial nos vasos axilares e braquiais em função do tipo de abordagem cirúrgica da axila (BLS ou LAT) em até seis meses após a intervenção. 2) Identificar os fatores que influenciam os parâmetros vasculares da veias axilares e braquiais ipsilaterais à cirurgia para tratamento do câncer de mama. Métodos: Foram identificadas 547 pacientes consecutivas, submetidas a tratamento cirúrgico para câncer de mama entre agosto de 2012 e janeiro de 2014. Depois de seguir critérios de inclusão e exclusão, 197 mulheres foram recrutadas. O projeto foi aprovado pelo comitê de ética do hospital e todos os pacientes assinaram o termo de consentimento informado. Os critérios de inclusão foram 1) câncer da mama primário operável 2) abordagem axilar cirúrgica; 3) não ter sido submetida a reconstrução da mama. Os critérios de exclusão foram 1) câncer de mama bilateral, 2) história prévia de procedimentos cirúrgicos para um dos membros superiores ou no tórax, 3) comprometimento ortopédico ou neurológico de um dos membros superiores, 4) insuficiência renal ou cardíaca. Todas as pacientes responderam a um breve questionário sobre suas características clínicas e epidemiológicas. Foi então realizada avaliação ultrassonográfica dos vasos braquiais e axilares, bilateralmente, nos seguintes momentos: no dia anterior à cirurgia e 1, 3, 6 e 12 meses após a cirurgia. No primeiro artigo, comparamos os parâmetros arteriais e venosos, até seis meses após a cirurgia, em função da realização de dissecção linfática completa ou linfonodo sentinela; no segundo, restringimos as análises ao sistema venoso e estendemos a avaliação para até 1 ano após a cirurgia, comparando os parâmetros vasculares em função de características clínicas e epidemiológicas das pacientes e das modalidades de tratamentos utilizados. Resultados: Foram encontradas restrições de diâmetro em veias do braço ipsilateral ao câncer de mama de mulheres submetidas à dissecção axilar (LAT), efeito que não foi observado no grupo BLS. A área da secção transversal de veias braquial e axilar diminuiu progressivamente até seis meses, com a redução do fluxo sanguíneo concomitante destes vasos. Encontramos, na mulher sem linfedema, que a área de secção transversal e fluxo venoso do sangue (especialmente veia braquial) são negativamente afetados pela cirurgia e / ou quimioterapia / radioterapia. Este efeito prejudicial parece persistir até um ano. Não houve diferença significativa em nenhum dos parâmetros estudados entre os vasos ipsi e contralaterais ao câncer de mama. Conclusões: De maneira geral, nosso estudo demonstra que os tratamentos cirúrgicos, especialmente LAT, e a radio e quimioterapia, possuem efeitos deletérios sobre a circulação sanguínea dos vasos axilares e braquiais, sobretudo venosos. Esses efeitos são aparentemente permanentes e há necessidade de extensão do tempo de follow-up a fim de avaliar se o desenvolvimento subsequente de linfedema ocorrerá em associação às alterações vasculares
Abstract: Objective: The aim of this thesis was to evaluate the arterial and venous vascular parameters of the axillary and brachial vessels in women who underwent treatment for breast cancer. We subdivided these assessments according to the following objectives, in two publications: 1) To compare the venous and arterial vascular parameters in the axillary vessels and brachial depending on the type of axillary surgical approach (SLNB or ALND) within six months after the intervention. 2) To identify which factors influence the vascular parameters of axillary and brachial veins ipsilateral to surgical for treatment of breast cancer. Methods: We identified 547 consecutive patients undergoing surgical treatment for breast cancer between August 2012 and January 2014. After following inclusion and exclusion criteria, 197 women were recruited. The project was approved by the hospital's ethics committee and all patients signed an informed consent form. Inclusion criteria were 1) primary operable breast cancer 2) surgical axillary approach; 3) not having undergone breast reconstruction. Exclusion criteria were 1) bilateral breast cancer, 2) history of previous surgical procedures for one of the upper limbs or breast, 3) orthopedic or neurological impairment of one upper limb, 4) kidney or heart failure. All patients completed a brief questionnaire about their clinical and epidemiological characteristics. Then we performed Doppler ultrasonography evaluation of axillary and brachial vessels, bilaterally, at the following times: the day before surgery and 1, 3, 6 and 12 months after surgery. In the first article, we compared the arterial and venous parameters, up to six months after surgery, depending on SLNB or ALND; in the second, we restricted the analysis to the venous system and extend the evaluation for up to 1 year after surgery, comparing the vascular parameters with clinical and epidemiological characteristics of patients and treatment modalities used. Results: diameter restrictions were found in the ipsilateral veins of the arm in women with breast cancer undergoing ALND, and that effect was not observed in SLNB group. The cross sectional area of brachial and axillary veins progressively decreased up to six months, with concomitant reduction of blood flow to these vessels. In women with no lymphedema, the cross-sectional area and venous blood flow (especially brachial vein) are negatively affected by surgery and / or chemotherapy / radiotherapy. This detrimental effect seems to persist up to one year. There was no significant difference on studied parameters between ipsilateral and contralateral vessels to breast cancer. Conclusions: In essence, our study shows that surgical treatments, especially ALND, and the radiation and chemotherapy, have deleterious effects on blood circulation of the axillary and brachial vessels, especially venous. These effects are apparently permanent, prompting the extension of the follow-up evaluation in order to assess whether subsequent lymphedema formation will be associated with vascular abnormalities
Doutorado
Oncologia Ginecológica e Mamária
Doutora em Ciências da Saúde
Mulla, Mubashir Ganie. "The role of cervical lymph node metastases and their dissection in papillary thyroid cancer employing different surgical approaches with regards to their long-term prognosis and outcomes." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/the-role-of-cervical-lymph-node-metastases-and-their-dissection-in-papillary-thyroid-cancer-employing-different-surgical-approaches-with-regards-to-their-longterm-prognosis-and-outcomes(070ff73f-7963-4b96-a085-8f22d8da8c73).html.
Повний текст джерелаQuadros, Claudio de Almeida. "Linfonodectomia retroperitoneal e pélvica lateral guiada por radiotraçador e azul patente no estadiamento do adenocarcinoma do reto." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-09122009-152351/.
Повний текст джерелаBACKGROUND: Total mesorectal excision is the standard surgical procedure for rectal adenocarcinoma treatment. Good prognostic results achieved with retroperitoneal and lateral pelvic lymphadenectomy have questioned that total mesorectal excision might not be satisfactory for adequate patient staging, affecting adjuvant therapeutic definitions. The aims of this study were to define the upstaging impact of metastasis to retroperitoneal and/or lateral pelvic nodes in patients with rectal adenocarcinoma and the accuracy of dye and/or probe search in the detection of metastatic retroperitoneal and/or lateral pelvic nodes. METHODS: A prospective study was carried on from January of 2004 to August of 2008, composed of 97 extraperitoneal rectal adenocarcinoma patients submitted to curative intent surgeries with total mesorectal excision and retroperitoneal and lateral pelvic lymphadenectomy, with retroperitoneal and lateral pelvic nodes mapping using technetium-99m-phytate and/or patent blue. The radioactive and/or blue nodes, when negative to histopathological hematoxylin-eosin staining, were submitted to step-sectioning and immunohistochemical examination with antibody against cytokeratin (AE1/AE3). RESULTS: Mean node count of the mesorectal excision specimen was 11.5 (1119/97) and of the retroperitoneal and lateral pelvic lymphadenectomy was 11.7 (1136/97). Retroperitoneal and lateral pelvic lymphadenectomy identified metastasis in 17.5% of the studied patients and modified TNM stage II to III in 8.2% of the patients. Factors related to metastatic retroperitoneal and lateral pelvic nodes were stage III defined by examination of the surgical specimen of the total mesorectal excision (P < 0,004); tumor pT3/pT4 classification (P = 0,047); high levels of carcinoembryonic antigen, with average of 30.6 ng/ml and median of 9.9 ng/ml (P = 0,014); and large tumors, with mean size of 5.5 cm ± 3,2 cm (P = 0,03). Technetium and/or patent blue migration to retroperitoneal and/or lateral pelvic nodes occurred in 37.1% (36/97), upstaging 11.1% of the studied patients. Technetium and/or patent blue accuracy in the detection of metastasis to retroperitoneal and/or lateral pelvic nodes was of 100%, with sensibility of 100%, negative predictive value of 100% and zero false negatives. CONCLUSIONS: The use of markers should be improved in the identification of metastasis for selective indication of retroperitoneal and lateral pelvic lymphadenectomy.
Fontana, Vivian. "Extensão do comprometimento axilar após biópsia de linfonodo sentinela positivo nas pacientes com câncer de mama operadas no Hospital de Clínicas de Porto Alegre." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2017. http://hdl.handle.net/10183/164317.
Повний текст джерелаIntroduction: The status of axillary lymph nodes remains one of the most important prognostic factors in breast carcinoma in the early stages, in addition it helps to defining the use of complementary therapies. Sentinel lymph node biopsy (SLNB) was developed with the purpose of staging the axilla with minimal morbidity, aiming at the identification and pathological study of the first axillary lymph node from the lymphatic drainage of the breast. Patients with clinically negative lymph node have indication of SLNB as a method of axillary staging, and with a positive finde for metastasis the axilar clereance was performed. Nowadays, due to the ACOSOG Z0011 Study, the axillary dissection (AD) after a positive SLNB for metastasis was put in check. This estudy have as a result no difference in global survive ou disease free survive if ALND was not performed in a positive SLNB. In the present study, we intend to evaluate the clinical and histopathological characteristics of patients submitted to breast conservative surgery and sentinel lymph node biopsy with a positive result for metastasis. Main objective: Evaluate the rate of recurrence and death in patients submitted to conservative breast surgery and BLNS with posterior axillary emptying at Hospital de Clínicas, Porto Alegre. It is a secondary objective to evaluate the clinical and pathological characteristics of this population. Material and Methods: A retrospective cohort study was performed, including 144 patients diagnosed with invasive breast carcinoma submitted to conservative breast surgery and SLNB, whose results were positive for metastases, and were submitted to AD, at the Mastology Unit of the Hospital de Clinicas de Porto Alegre (HCPA), from January 2004 to December 2008. Results: Of 144 patients submitted to SLNB and BCS, 33 had SLNB positive for metastasis, of these 33 patients remained 27 for data analysis. The success rate in LNS identification was 0.96. The mean age of the patients was 53.8 years, the number of resected SLN was 1.6 per patient; The mean tumor size was 2.3 cm. Six patients had residual axillary disease corresponding to 22.2% of the sample and had a relative risk of death of 3 times more for those without residual axillary disease and 50% more for the development of metastases. Conclusion: Axillary involvement is an important factor in the prognosis of patients with breast cancer, and the greater the axillary impairment, the worse the diseasefree survival outcome and death. We believe that the ACOSOG Z0011 trial can also be applied to HCPA patients who meet the inclusion criteria for this purpose, due to the high sensitivity of the method in our environment.
Antonio, Heriton Marcelo Ribeiro. "Linfonodo sentinela e dissecção axilar: análise da disfunção de membros superiores." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/17/17145/tde-05012016-104011/.
Повний текст джерелаBreast cancer is a malignancy that affects more women in the Brazilian population. Currently the treatment for breast cancer is based on three pillars: radiotherapy, surgery in its various techniques, chemotherapy / hormone therapy. Quality of life may be affected in general, involving the physical, psychological, sociological, emotional, and others. The aim of this study was to compare the upper limb function in patients with breast cancer who underwent sentinel lymph node biopsy with axillary dissection underwent, and were not accompanied by a rehabilitation protocol pre-established. Patients and methods: we evaluated 36 patients who underwent axillary dissection (group DA), 29 who underwent sentinel lymph node biopsy (SNB group) and 11 normal subjects (group SN). Results: We found that the DA group presents a risk of loss of function for flexion and shoulder abduction in the order of 5 and 3.7 times higher than the BLS group, respectively. We also found that patients who underwent SNB evolve with significant dysfunction for flexion and shoulder abduction when not undergoing physiotherapy intervention. Conclusion: The DA has a higher dysfunction in upper limb when compared with BLS. The rehabilitation of patients who underwent SNB can not be ignored because this surgery can lead to significant dysfunction of the ipsilateral upper limb
Capelli, Fabio de Aquino. "Quantificação dos linfonodos em espécimes de esvaziamento cervical: estudo morfológico." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-22082016-150641/.
Повний текст джерелаINTRODUCTION: Neck dissection is an important part of the treatment of head and neck neoplasms and also perform a staging function, by quantifying the lymph nodes and verifying their degree of involvement by the disease. In this study the amount of lymph nodes in modified radical neck dissection specimens conducted in a series of non-preserved cadavers was accessed, trying to define parameters which determine the minimum desired number of lymph nodes in a neck dissection performed in clinical practice, as well as the number of lymph nodes in each level of the neck dissection. The study also seeks to determine whether there is a relationship between the number of lymph nodes in the specimens of modified radical neck dissection and demographic and anthropometric data of the cadaver. METHODS: Cross-sectional anatomical study conducted in 28 non-preserved cadavers dissected in the Serviço de Verificação de Óbitos of the University of São Paulo, reproducing the modified radical neck dissection technique bilaterally, with the removal of fibroadipose tissue that contains the deep cervical lymph nodes, level by level, according to the division and anatomical limits recommended by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery. Specimens were manually dissected by the same pathologist, with separation of the lymph nodes, which were placed in cassettes and stored in separate vials for each level, containing phosphate buffered formalin 10% solution. The remaining fat tissue was also included for further evaluation. The analysis of the slides stained with hematoxylin and eosin aimed to confirm manually dissected lymph nodes and to determine the presence of microscopic lymph nodes. RESULTS: There were 28 cadavers; 18 (64.3%) were male and the mean age was 67.4 ± 10.3 years. Fifteen subjects were classified as caucasian (53.6%), 12 afrodescendants (42.9%) and one asian (3.6%), with average weight of 59.6 ± 13.3 kg, mean height of 164 ± 9.1 cm and mean body mass index (BMI) of 22.0 ± 3.9 kg/m2. The average number of lymph nodes found in the levels of the 56 modified radical neck dissections performed were: level IA - 1.5 (95% CI: 1.1 - 1.8), level IB - 2.5 (95% CI: 2.1 - 2.9), level IIA - 7.2 (95% CI: 6.0 - 8.5), IIB level - 6.5 (95% CI: 5.5 - 7.4), level III - 6.6 (95% CI: 5.7 - 7.4), level IV - 8.6 (95% CI: 7.1 - 10.1), level V - 11 (95% CI: 9.2 - 12.7), totalizing 43.8 lymph nodes (95% CI: 40.3 - 47.4). The number of lymph nodes in the left side level IV was higher in males compared to females (11.9 X 7.2; P=0.040 - Mann-Whitney´s test), and correlated positive with height (r=+ 0.396, P=0.037 - Spearman´s correlation test). The amount of lymph nodes in the right side level V, and also when considered both sides of the neck, had positive correlation with the weight (r=+ 0.417 P=0.027 e r=+ 0.278, P=0.038; respectively, Spearman´s correlation test) and BMI (r=+ 0.456, P=0.015 e r=+0.317, P=0.021; respectively, Spearman´s correlation test) of the individual. The total number of lymph nodes in each neck dissection had a negative correlation with age (r=-0.358, P=0.007 - Spearman´s correlation test). There were no differences in relation to the race of individuals. CONCLUSIONS: The results defined a parameter in relation to the minimum recommended number of lymph nodes to be recovered in a modified radical neck dissection specimen, as well as on each level of this dissection, performed in clinical practice. There was association among the number of lymph nodes identified in specimens of modified radical neck dissection and some demographic and antropometric features: sex, height, age, weight and body mass index of the cadaver
Steck, José Higino. "Validade do mapeamento do linfonodo sentinela na detecção de metástase linfática cervical do carcinoma papilífero da glândula tireoide." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-06092016-145112/.
Повний текст джерелаINTRODUCTON: Sentinel lymph node mapping (SLNM) is widely perfomed in melanoma, breast cancer and other solid tumors, to adequately stage these diseases. More recently, the interest in SLNM for clinically N0 Papillary Thyroid Cancer (PTC) has increased due to the high rate of occult metastases in these patients, to avoid unnecessary central neck dissection (CND), and its complications. Even if routine elective CND is not planned, SLNM can be used to adequately stage the neck, and to indicate further treatment with radioiodine in cases with neck metastases, for instance. This study aims to evaluate 1) SLNM effectiveness in PTC patients, 2) SLNM accuracy to diagnosis lymph node metastases and 3) if SLNM can upstage cN0 PTC patients. METHODS: This is a prospective longitudinal, diagnostic test accuracy study with 38 consecutive cN0 PTC patients, treated in a single center between 2010 and 2015. Surgical treatment in all cases included total thyroidectomy and elective CND after SLNM. Results of SLNM were compared to CND pathological findings, in order to verify if sentinel lymph node (SLN) predicted the occurrence of PTC occult lymph node metastasis. RESULTS: The mean patients\' follow-up was 36 ± 13 months. 133 SLN were found in the neck, on levels VI and III. The SLN was identified in 95% of the patients with 1 false negative, 95% sensitivity, 94% negative predictive value and 97% accuracy. The SLNM upstaging from cN0 to pN+ was 49%, with 3% stage III and 18% stage IVa. CONCLUSION: 1) SLNM was effective in 95% of procedures, 2) SLNM accuracy was 97%, 3) SLNM upstaging from cN0 to pN+ was 49%, and to stage III and IVa was 21%
Kroon, Hidde Maarten. "Management of Lateral Lymph Node Metastasis in Rectal Cancer." Thesis, 2022. https://hdl.handle.net/2440/135590.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, Adelaide Medical School, 2022
Alyea, Jennifer Marie. "Utilization Patterns of Lymph Node Dissection in Endometrial Cancer Patients Without Distant Metastasis in the United States." Diss., 2021. http://hdl.handle.net/1805/26253.
Повний текст джерелаEndometrial cancer is the most common gynecologic cancer in the United States, and patients with early-stage endometrioid adenocarcinoma have a favorable prognosis. Over the past decade, the gynecologic oncology community has debated whether potential harms of systematic lymph node dissection (LND) outweigh potential benefits for these patients. To minimize number of nodes removed, sentinel lymph node dissection (SLND) is under investigation as an alternative. However, ongoing uncertainty of LND/SLND best practices may result in variations in disease management and discrepant outcomes. Methods Three retrospective cohort studies examined LND/SLND use in patients with endometrioid adenocarcinoma. Two examined temporal and geographic variations, respectively, utilizing the Surveillance, Epidemiology, and End Results (SEER) 18 dataset for the years 2004 through 2015. The third used the SEER-Medicare dataset from 2003 through 2016 to quantify and compare the risk of developing 6-month post-surgical lymphedema, lymphocele, hemorrhage, ileus, infection, thrombosis, and all-cause death by number of lymph nodes removed (0, 1-4, 5-9, or 10+). Results Time trend analyses found LND increased from 2004 through 2008, followed by a significant decline through 2015. SLND was rare and did not increase significantly. Significant geographic variation existed for LND use but not SLND. Per 1,000 patients, analyses of 6-month post-surgical complications found 6.5 experienced lymphedema, 3.9 experienced lymphocele, 15.7 experienced hemorrhage, 28.7 experienced ileus, 37.1 experienced infection, 18.6 experienced thrombosis, and 19.8 died. Controlling for size of primary tumor, tumor grade, comorbidities, race/ethnicity, age at diagnosis, adjuvant chemotherapy, and radiotherapy, adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) showed greater risk for ileus (HR: 1.53; 95% CI: 1.24-1.90), infection (HR: 1.52; 95% CI: 1.25-1.83), and thrombosis (HR: 1.41; 95% CI: 1.09-1.82) when comparing removal of 10+ nodes versus 0 nodes. Conclusion Overall, these studies found significant temporal and geographic variation in LND, as well as increasing risk of post-surgical complications associated with increasing numbers of lymph nodes removed. Should continued research into SLND find strong evidence that it effectively detects cancer spread, patients may benefit through decreased risk of post-surgical ileus, infection, and thrombosis.
Wells, Bryan John. "A Comparison of the Costs of Sentinel Lymph Node Biopsy and of Axillary lymph Node Dissection in the Management of Early-stage Breast Cancer in Ontario." Thesis, 2009. http://hdl.handle.net/1807/18993.
Повний текст джерелаSHIE, YA-FANG, and 謝亞芳. "Resources Utilization and Clinical Outcome of Neck Lymph Node Dissection in Early Tongue Cancer Patient." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/77976246971029881419.
Повний текст джерела高雄醫學大學
醫務管理學研究所碩士在職專班
98
According to annual registry report announced by the Taiwan Cancer Registry, Bureau of Health Promotion, Department of Health, R.O.C. (Taiwan), it was noted the number of oral cancers increased from 4873 in 2004 to 5352 in 2006. Oral cancer was the sixth common malignancy encountered in Taiwan. Tongue cancer accounting for 27 % ~28% of total oral cancer cases has the highest incidence in oral cancer. Consensus about cervical lymph node dissection has been reached in patients with clinical stage T3, and T4 N0 tongue cancer patients, however, whether cervical lymph node dissection should be performed in the T1 and T2 N0 patients remained to be studied. In this paper, we analyzed the efficacy and cost-effectiveness of elective cervical node dissection for early tongue cancer patients. Our results showed there was no significant difference between patients with elective neck dissection (END) and those without in local recurrence, recurrence of cervical lymph node and distant metastasis. There was also no significant difference between the Wait and Watch (WW) group and the Elective Neck Dissection (END) group in five-year overall survival. In terms of medical resource utilization, there was no significant difference between WW and END groups. The outpatient fees per month for the Wait and Watch (WW) and the Elective Neck Dissection (END) were NT$4,027, and NT$5,631, respectively. No significant difference between two groyps. About 40% of the patients among the study cases have experienced recurrence or metastatic lymph nodes within five years. The results of logistic regression analysis revealed that perineural invasion is a significant factor to predictor recurrence. In conclusion, our study showed no significant difference in 5-year overall survival and recurrence between END and WW groups. The medical cost was higher in the END group than in WW group in the first admission. Our results implicate elective neck dissection should be cautiously considered for those patients with early tongue cancer.
Rodrigues, Cláudia Sofia dos Santos Ferreira. "Melanoma cutâneo: Interesse da biópsia do gânglio sentinela e do esvaziamento ganglionar." Master's thesis, 2019. http://hdl.handle.net/10316/89972.
Повний текст джерелаIntrodução: A incidência de melanoma cutâneo aumentou significativamente nas últimas décadas e apesar de corresponder a menos de 10% dos tumores cutâneos, é responsável pela maioria das mortes por cancro de pele. A biópsia do gânglio sentinela permite a deteção de doença ganglionar clinicamente oculta e caso esta seja positiva está preconizada a realização de esvaziamento ganglionar do território linfático respetivo, procedimentos estes envoltos em controvérsia por não estar demonstrado terem impacto na sobrevivência. Materiais e Métodos: Esta revisão sistemática tem como objetivos principais responder a duas questões clínicas principais – o interesse da biópsia do gânglio sentinela e do esvaziamento ganglionar. Para a sua elaboração foram consultadas as bases de dados PubMed e Embase com pesquisa confinada aos últimos 5 anos, obtendo-se 526 fontes bibliográficas, ficando 50 após critérios de exclusão. Foram ainda adicionadas 5 referências para melhor contextualizar o tema, perfazendo um total de 55 fontes bibliográficas finais. Resultados: Em relação à biópsia do gânglio sentinela a maioria dos estudos comprova que esta não está associada a uma melhoria significativa em termos de sobrevivência mas está associada a uma melhoria significativa em relação ao tempo de recorrência ganglionar da doença por melhor controlo regional. Em relação ao esvaziamento ganglionar, também se constata, de uma forma geral, que os estudos não demonstram melhoria de taxas de sobrevivência, demonstrando menores taxas de recorrência ganglionar. Conclusão: A biópsia do gânglio sentinela e o esvaziamento ganglionar devem ser recomendadas a subpopulações específicas com base em decisões individuais e apesar de não promoverem melhoria da sobrevida promovem melhor controlo regional da doença, ajuda no estadiamento, informação prognóstica e decisão terapêutica. Uma alternativa viável a estes procedimentos que acarretam morbilidade e custos é a observação ganglionar frequente com ecografia. No entanto, por falta de estudos com elevada evidência científica, aguarda-se por mais estudos randomizados e controlados que analisem várias subpopulações e afiram o real valor da realização destes procedimentos nessas várias subpopulações consideradas, definindo critérios para renunciar a sua realização.
Introduction: The incidence of cutaneous melanoma has increased significantly in recent decades and although it accounts for less than 10% of cutaneous tumors, it accounts for the majority of skin cancer deaths. Sentinel lymph node biopsy allows the detection of clinically occult lymph node disease and, if this is positive, lymph node dissection of the lymphatic region is recommended. These procedures are involved in controversy because they don’t show an impact on survival. Materials and Methods: This systematic review has as main objectives answer two main clinical questions – the interest of the sentinel lymph node biopsy and the interest of lymph node dissection. In order to prepare this work, there have been consulted the databases PubMed and Embase with search confined to the last 5 years, obtaining 526 records, 50 after exclusion criteria. For better contextualize the theme 5 records were added, making a total of 55 final bibliographic sources. Results: Most studies show that sentinel lymph node biopsy isn’t associated with a significant improvement in survival but is associated with a significant improvement in disease nodal recurrence due to better regional control. About lymph node dissection is also generally observed that the studies don’t show improvement in survival outcomes but they show lower rates of lymph node recurrence. Conclusion: Sentinel lymph node biopsy and lymph node dissection should be recommended to specific subpopulations based on individual decisions, and although they don’t improved survival, they promote better regional disease control, staging aid, prognostic information and support therapeutic decisions. A viable alternative to these procedures that cause morbidity and costs is frequent nodal observation with ultrasonography. However, due to lack of studies with high scientific evidence, we are expecting more randomized and controlled studies that analyse several subpopulations and point out the real value of performing these procedures in these several subpopulations considered, defining criteria to avoid their execution.
Klein, Evelyn [Verfasser]. "Evaluation of side effects after axillary lymph node dissection for breast cancer taking tumour staging status into account / Evelyn Klein." 2009. http://d-nb.info/1006965459/34.
Повний текст джерелаLöffler, Julia Angelika [Verfasser]. "Risk factors for a positive sentinel lymph node dissection in cutaneous melanoma : does the surgeon play a role? / vorgelegt von Julia Angelika Löffler." 2010. http://d-nb.info/1005327866/34.
Повний текст джерелаHANNA, TIMOTHY. "A Population-Based Study of Factors Affecting Access to Radiotherapy for Endometrial Cancer in Ontario." Thesis, 2009. http://hdl.handle.net/1974/2593.
Повний текст джерелаThesis (Master, Community Health & Epidemiology) -- Queen's University, 2009-08-07 22:02:37.308
Kolařík, Dušan. "Populace buněk karcinomu prsu. Využití pro stanovení optimálního terapeutického postupu. Prediktivní model." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-351520.
Повний текст джерелаPratsch, Aila Luise. "Beinschwellungen nach inguinaler Lymphknotenchirurgie - Eine multimodale Untersuchung zu Prävalenz und Einflussfaktoren." Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F015-C.
Повний текст джерелаReißig, Franziska. "Leitliniengerechte operative Versorgung von Primärmelanomen und Evaluation individueller Abweichungen." 2018. https://ul.qucosa.de/id/qucosa%3A33418.
Повний текст джерелаHashim, Che Gon. "Identifying predictors of postoperative persistent pain in women with breast cancer: assessments of investigative tools." Master's thesis, 2018. http://hdl.handle.net/1885/162744.
Повний текст джерела