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Статті в журналах з теми "Late gadolinium magnetic resonance imaging"

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Автор: Grafiati

Опубліковано: 7 липня 2024

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1

Lee, Daniel C., Monique E. Hinchcliff, Roberto Sarnari, Madeline M. Stark, Jungwha Lee, Kimberly Koloms, Aileen Hoffmann, et al. "Diffuse cardiac fibrosis quantification in early systemic sclerosis by magnetic resonance imaging and correlation with skin fibrosis." Journal of Scleroderma and Related Disorders 3, no. 2 (April 12, 2018): 159–69. http://dx.doi.org/10.1177/2397198318762888.

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Purpose: To evaluate the utility of cardiac magnetic resonance T1 mapping in early systemic sclerosis and its association with skin score. Methods: In total, 24 consecutive patients with early systemic sclerosis referred for cardiovascular evaluation and 12 controls without systemic sclerosis were evaluated. All patients underwent cine, T1 mapping, and late gadolinium–enhanced cardiac magnetic resonance imaging. T1 mapping indices were compared between systemic sclerosis patients and controls (extracellular volume fraction, gadolinium partition coefficient (λ), pre-contrast T1, and post-contrast T1). The association between T1 mapping parameters and the modified Rodnan skin score was determined. Results: There were no significant differences in cardiac structure/function between systemic sclerosis patients and controls on cine imaging, and 8 of 24 (33%) systemic sclerosis patients had evidence of late gadolinium–enhanced cardiac magnetic resonance imaging (i.e. focal myocardial fibrosis). Of the T1 mapping parameters (indices indicative of diffuse myocardial fibrosis), extracellular volume fraction differentiated systemic sclerosis patients from controls the best, followed by λ, even when the eight systemic sclerosis patients with late gadolinium–enhanced cardiac magnetic resonance imaging were excluded. Extracellular volume fraction had a sensitivity and specificity of 75% and 75% for diffuse myocardial fibrosis (optimal abnormal cutoff value of >27% (area under receiver operating characteristic curve = 0.85)). In the 16 patients without evidence of late gadolinium–enhanced cardiac magnetic resonance imaging, each of the four cardiac magnetic resonance T1 mapping parameters (extracellular volume fraction, λ, Pre-T1 and Post-T1) correlated with modified Rodnan skin score ( R = 0.51–0.65, p = 0.007–0.043), indicating a correlation between systemic sclerosis cardiac and skin fibrosis. Conclusion: The four T1 mapping indices are significantly correlated with modified Rodnan skin score in patients with early systemic sclerosis. Quantification of diffuse myocardial fibrosis using extracellular volume fraction should be considered as a marker for cardiac involvement in systemic sclerosis clinical studies.

2

Ricco, A., J. Canada, J. Grizzard, F. Dana, L. Rezai Gharai, K. Neiderer, A. Vera, A. Abbate, and E. Weiss. "Late Gadolinium Enhancement (LGE) in Cardiac Magnetic Resonance Imaging (CMR)." International Journal of Radiation Oncology*Biology*Physics 102, no. 3 (November 2018): S224—S225. http://dx.doi.org/10.1016/j.ijrobp.2018.07.152.

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3

Han, Yuchi, Yucheng Chen, and Victor A. Ferrari. "Contemporary Application of Cardiovascular Magnetic Resonance Imaging." Annual Review of Medicine 71, no. 1 (January 27, 2020): 221–34. http://dx.doi.org/10.1146/annurev-med-041818-015923.

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Cardiovascular magnetic resonance imaging (CMR) is a comprehensive and versatile diagnostic and prognostic imaging modality that plays an increasingly important role in management of patients with cardiovascular disease. In this review, we discuss CMR applications in nonischemic cardiomyopathy, ischemic heart disease, arrhythmias, right ventricular diseases, and valvular heart disease. We emphasize the quantitative nature of CMR in current practice, from volumes, function, myocardial strain analysis, and late gadolinium enhancement to parametric mapping, including T1, T2, and T2* relaxation times and extracellular volume fraction assessment.

4

Gilard, Martine, Mourad Mejri, Pennec Pierre-Yves, and Jacques Boschat. "Magnetic Resonance Imaging for the Interventional Cardiologist." Interventional Cardiology Review 4, no. 1 (2009): 26. http://dx.doi.org/10.15420/icr.2009.4.1.26.

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Cardiovascular magnetic resonance imaging (MRI) has evolved over the last few years into a valuable tool for the diagnosis and management of cardiovascular diseases. Late gadolinium-enhanced MRI and stress myocardial perfusion MRI have been shown to be useful in detecting infarct tissue and in predicting myocardial viability and patient prognosis. The strengths of MRI lie in its ability to comprehensively image cardiac anatomy, function, perfusion, viability and physiology in ‘one-stop testing’ and to provide high-quality diagnostic information without the need for radiation. This article summarises the current clinical applications of MRI in interventional cardiology.

5

Vöhringer, Matthias, Heiko Mahrholdt, Ali Yilmaz, and Udo Sechtem. "Significance of Late Gadolinium Enhancement in Cardiovascular Magnetic Resonance Imaging (CMR)." Herz Kardiovaskuläre Erkrankungen 32, no. 2 (March 2007): 129–37. http://dx.doi.org/10.1007/s00059-007-2972-5.

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6

Nucifora, Gaetano, and Joseph B. Selvanayagam. "Cardiac Magnetic Resonance Late Gadolinium Enhancement Imaging in Arrhythmic Risk Stratification." Heart, Lung and Circulation 29, no. 9 (September 2020): 1268–69. http://dx.doi.org/10.1016/j.hlc.2020.07.001.

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7

Himcinschi, Elisabeta, Elena Beganu, Lehel Bordi, Roxana Hodas, and Theodora Benedek. "Magnetic Resonance Imaging in Myocardial Fibrosis Related to Ischemic Events." Journal of Interdisciplinary Medicine 2, no. 3 (September 1, 2017): 250–53. http://dx.doi.org/10.1515/jim-2017-0067.

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Abstract Given the higher amount of detail it offers, the use of magnetic resonance (MR) in the field of cardiology has increased, thus leading to a decrease in the use of invasive and irradiating methods for diagnosing various cardiovascular disorders. The only precautions for MR imaging are metallic implants and advanced-stage chronic kidney disease. For the acquisition of clear and dynamic myocardial images, methods such as spin echo imaging for anatomical description, steady-state free precession imaging for the assessment of ventricular cavity size and function, flow velocity encoding for blood flow measurements, radiofrequency tagging for dynamics, and even spectroscopy for metabolism evaluation are used. Cardiac magnetic resonance (CMR) is considered the gold standard imaging method for the anatomical characterization of the heart and obtaining information related to myocardial dynamics. In case of ischemic events, CMR is used for a detailed description of the necrotic area and the complications, and for tracking the ventricular remodeling. By administrating a contrast agent (gadolinium), the difference between sub-endothelial and transmural infarctions can be distinguished, highlighting even microvascular lesions responsible for the extension of the necrosis. The assessment of the dynamics of ventricular remodeling and viability through late gadolinium enhancement (LGE) technology highlights the area of fibrosis and the occurrence of late complications.

8

Dara, Bharat S., Paolo G. Rusconi, and Joel E. Fishman. "Danon disease: characteristic late gadolinium enhancement pattern on cardiac magnetic resonance imaging." Cardiology in the Young 21, no. 6 (May 19, 2011): 707–9. http://dx.doi.org/10.1017/s1047951111000564.

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AbstractDanon disease is a rare entity associated with the clinical triad of mental retardation, skeletal myopathy, and severe hypertrophic cardiomyopathy. We report two cases of Danon disease and describe the results of the cardiac magnetic resonance imaging studies that were conducted to assess the pattern of cardiac hypertrophy.

9

Ichikawa, Yasutaka, Hajime Sakuma, Naohisa Suzawa, Kakuya Kitagawa, Katsutoshi Makino, Tadanori Hirano, and Kan Takeda. "Late gadolinium-enhanced magnetic resonance imaging in acute and chronic myocardial infarction." Journal of the American College of Cardiology 45, no. 6 (March 2005): 901–9. http://dx.doi.org/10.1016/j.jacc.2004.11.058.

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10

Siebermair, Johannes, Eugene G. Kholmovski, and Nassir Marrouche. "Assessment of Left Atrial Fibrosis by Late Gadolinium Enhancement Magnetic Resonance Imaging." JACC: Clinical Electrophysiology 3, no. 8 (August 2017): 791–802. http://dx.doi.org/10.1016/j.jacep.2017.07.004.

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11

Burrage, Matthew K., and Vanessa M. Ferreira. "Cardiovascular Magnetic Resonance for the Differentiation of Left Ventricular Hypertrophy." Current Heart Failure Reports 17, no. 5 (August 26, 2020): 192–204. http://dx.doi.org/10.1007/s11897-020-00481-z.

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Abstract Purpose of Review Left ventricular hypertrophy (LVH) is a common presentation encountered in clinical practice with a diverse range of potential aetiologies. Differentiation of pathological from physiological hypertrophy can be challenging but is crucial for further management and prognostication. Cardiovascular magnetic resonance (CMR) with advanced myocardial tissue characterisation is a powerful tool that may help to differentiate these aetiologies in the assessment of LVH. Recent Findings The use of CMR for detailed morphological assessment of LVH is well described. More recently, advanced CMR techniques (late gadolinium enhancement, parametric mapping, diffusion tensor imaging, and myocardial strain) have been used. These techniques are highly promising in helping to differentiate key aetiologies of LVH and provide valuable prognostic information. Summary Recent advancements in CMR tissue characterisation, such as parametric mapping, in combination with detailed morphological assessment and late gadolinium enhancement, provide a powerful resource that may help assess and differentiate important causes of LVH.

12

Pavlov, A. V., T. P. Gizatulina, and V. A. Kuznetsov. "Electroanatomic bipolar mapping for detection of arrhythmogenic substrate in catheter ablation of atrial fibrillation." Jounal of arrhythmology 26, no. 4 (February 20, 2020): 32–38. http://dx.doi.org/10.35336/va-2019-4-32-38.

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The article presents data comparing the results of late gadolinium-enhanced magnetic-resonance imaging and bipolar mapping. The results of studies on the use of bipolar mapping data for substrate modification in catheter ablation of atrial fibrillation are presented, and perspectives for the development of the method are indicated.

13

Tsabedze, Nqoba, Andre du Plessis, Dineo Mpanya, Anelia Vorster, Quinn Wells, Leonie Scholtz, and Pravin Manga. "Cardiovascular Magnetic Resonance Imaging Findings in Africans with Idiopathic Dilated Cardiomyopathy." Diagnostics 13, no. 4 (February 8, 2023): 617. http://dx.doi.org/10.3390/diagnostics13040617.

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In sub-Saharan Africa, idiopathic dilated cardiomyopathy (IDCM) is a common yet poorly investigated cause of heart failure. Cardiovascular magnetic resonance (CMR) imaging is the gold standard for tissue characterisation and volumetric quantification. In this paper, we present CMR findings obtained from a cohort of patients with IDCM in Southern Africa suspected of having a genetic cause of cardiomyopathy. A total of 78 IDCM study participants were referred for CMR imaging. The participants had a median left ventricular ejection fraction of 24% [interquartile range, (IQR): 18–34]. Late gadolinium enhancement (LGE) was visualised in 43 (55.1%) participants and localised in the midwall in 28 (65.0%) participants. At the time of enrolment into the study, non-survivors had a higher median left ventricular end diastolic wall mass index of 89.4 g/m2 (IQR: 74.5–100.6) vs. 73.6 g/m2 (IQR: 51.9–84.7), p = 0.025 and a higher median right ventricular end-systolic volume index of 86 mL/m2 (IQR:74–105) vs. 41 mL/m2 (IQR: 30–71), p < 0.001. After one year, 14 participants (17.9%) died. The hazard ratio for the risk of death in patients with evidence of LGE from CMR imaging was 0.435 (95% CI: 0.259–0.731; p = 0.002). Midwall enhancement was the most common pattern, visualised in 65% of participants. Prospective, adequately powered, and multi-centre studies across sub-Saharan Africa are required to determine the prognostic significance of CMR imaging parameters such as late gadolinium enhancement, extracellular volume fraction, and strain patterns in an African IDCM cohort.

14

Liu, Guiying, Xi Yang, Ying Su, Jimin Xu, and Zhaoying Wen. "Cardiovascular magnetic resonance imaging findings in children with myocarditis." Chinese Medical Journal 127, no. 21 (November 5, 2014): 3700–3705. http://dx.doi.org/10.3760/cma.j.issn.0366-6999.20132300.

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Background Myocarditis is a common, potentially life-threatening disease that presents a wide rang of symptoms in children, as an important underlying etiology of other myocardial diseases such as dilated and arrhythmogenic right ventricular cardiomyopathy. The incidence of nonfatal myocarditis is probably greater than that of the one actually diagnosed, which is the result of the challenges of establishing the diagnosis in standard clinical settings. Currently, no single clinical or imaging finding confirms the diagnosis of myocarditis with absolute certainty. Historically, clinical exam, electrocardiogram (ECG), serology and echocardiography had an unsatisfactory diagnostic accuracy in myocarditis. Endomyocardial biopsy remains as a widely accepted standard, but may not be suitable for every patient, especially for those with less severe disease. Our aim was to find the changes in cardiovascular magnetic resonance (CMR) imaging of children with myocarditis diagnosed by clinical criteria. Methods We studied 25 children (18 male, 7 female; aged from 5–17 years) with diagnosed myocarditis by clinical criteria. CMR included function analyses, T2-weighted imaging, T1-weighted imaging before and after i.v. gadolinium injection (early gadolinium enhancement (EGE) and late gadolinium enhancement (LGE)). Results The T2 ratio was elevated in 21 children (84%, 11 in anterolateral (44%), 5 in inferolateral (20%), and 5 in septum (20%)), EGE was present in 9 children (36%, 3 in anterolateral (12%), 4 in inferolateral (20%), and 2 in septum (8%)), and LGE was present in 5 children (20%, 2 in anterolateral (8%), 1 in inferolateral (4%), 1 in septum (4%), and 1 in midwall of left ventricular (LV) wall). In 9 children (36%), two (or more) out of three sequences (T2, EGE, LGE) were abnormal. Conclusions The CMR findings in children with clinically diagnosed myocarditis vary within the groups, including regional or global myocardial signal increase in T2-weighted images, EGE and LGE in T1-weighted images. The T2 ratio elevation is the most common CMR finding. Children with mild cardiac symptoms may also appear serious myocardial injuries.

15

Ojha, Vineeta, Rishabh Khurana, Kartik P. Ganga, and Sanjeev Kumar. "Advanced cardiac magnetic resonance imaging in takotsubo cardiomyopathy." British Journal of Radiology 93, no. 1115 (November 1, 2020): 20200514. http://dx.doi.org/10.1259/bjr.20200514.

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Takotsubo cardiomyopathy (TC) is a reversible condition in which there is transient left ventricular (LV) dysfunction characterised most commonly by basal hyperkinesis and mid-apical LV ballooning and hypokinesia. It is said to be triggered by stress and mimics, such as acute coronary syndrome (ACS) clinically. Diagnosis is usually suspected on echocardiography due to the characteristic contraction pattern in a patient with symptoms and signs of ACS but normal coronary arteries on catheter angiography. Cardiac magnetic resonance (CMR), with its latest advancements, is the diagnostic modality of choice for diagnosis, prognosis and follow-up of patients. The advances in CMR (including T1, T2, ECV mapping and threshold-based late gadolinium enhancement (LGE) measurements have revolutionised the role of CMR in tissue characterisation and prognostication in patients with TC. In this review, we highlight the current role of CMR in management of TC and enumerate the CMR findings in TC as well the current advances in the field of CMR, which could help in prognosticating these patients.

16

Bouabdallaoui, N., P. V. Ennezat, E. Durand, E. Puymirat, and L. Macron. "Late gadolinium enhancement cardiac magnetic resonance imaging in prognostic assessment of hypertrophic cardiomyopathy." European Heart Journal - Cardiovascular Imaging 14, no. 10 (May 3, 2013): 1024. http://dx.doi.org/10.1093/ehjci/jet067.

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17

Safiullina, A. A., M. A. Shariya, O. U. Narusov, A. U. Shedrina, A. A. Scvortsov, and S. N. Tereshchenko. "Late gadolinium enhancement on cardiac magnetic resonance imaging in patients with inflammatory cardiomyopathy." European Heart Journal 34, suppl 1 (August 2, 2013): P5738. http://dx.doi.org/10.1093/eurheartj/eht310.p5738.

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18

Sato, Takahiro, Ichizo Tsujino, Hiroshi Ohira, Noriko Oyama-Manabe, Yosuke Yamada, Noriyuki Otsuka, and Masaharu Nishimura. "Right Atrial Late Gadolinium Enhancement on Cardiac Magnetic Resonance Imaging in Pulmonary Hypertension." Circulation Journal 76, no. 1 (2012): 238–39. http://dx.doi.org/10.1253/circj.cj-11-0585.

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19

Hanneman, Kate, Gauri R. Karur, Syed Wasim, Chantal F. Morel, and Robert M. Iwanochko. "Prognostic Significance of Cardiac Magnetic Resonance Imaging Late Gadolinium Enhancement in Fabry Disease." Circulation 138, no. 22 (November 27, 2018): 2579–81. http://dx.doi.org/10.1161/circulationaha.118.037103.

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20

Wu, Ching-Fen, Wen-Po Chuang, Ai-Hsien Li, and Chi-Huang Hsiao. "Cardiac Magnetic Resonance Imaging in Sunitinib Malate-related Cardiomyopathy: No Late Gadolinium Enhancement." Journal of the Chinese Medical Association 72, no. 6 (June 2009): 323–27. http://dx.doi.org/10.1016/s1726-4901(09)70379-x.

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21

Yamakoshi, Kazunori. "Optimal Imaging Method for Late Gadolinium-enhanced Cardiovascular Magnetic Resonance in Arrhythmic Cases." Japanese Journal of Radiological Technology 75, no. 12 (2019): 1411–19. http://dx.doi.org/10.6009/jjrt.2019_jsrt_75.12.1411.

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22

Krittayaphong, Rungroj, Vithaya Chaithiraphan, Adisak Maneesai, and Suthipol Udompanturak. "Prognostic value of combined magnetic resonance myocardial perfusion imaging and late gadolinium enhancement." International Journal of Cardiovascular Imaging 27, no. 5 (April 10, 2011): 705–14. http://dx.doi.org/10.1007/s10554-011-9863-9.

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23

Liu, Xiao-Hang, Tian-Chen Guo, Yi-Ning Wang, Li Huo, and Wei Chen. "Reexamination of cardiac magnetic resonance imaging showed the improvement of late gadolinium enhancement." ASVIDE 10 (September 2023): 168. http://dx.doi.org/10.21037/asvide.2023.168.

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24

Doltra, Adelina, Philipp Stawowy, Thore Dietrich, Christopher Schneeweis, Eckart Fleck, and Sebastian Kelle. "Magnetic Resonance Imaging of Cardiovascular Fibrosis and Inflammation: From Clinical Practice to Animal Studies and Back." BioMed Research International 2013 (2013): 1–10. http://dx.doi.org/10.1155/2013/676489.

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Late gadolinium enhancement is the technique of choice for detecting myocardial fibrosis. Although this technique is used in a wide range of cardiovascular pathologies, ischemic cardiomyopathy and the workup for myocarditis and other cardiomyopathies make up a significant proportion of the total indications. Multiple studies during the last decade have demonstrated its utility to adequately characterize myocardial tissue and offer diagnostic and prognostic information. Recent T1 mapping techniques aim to overcome the limitations of late gadolinium enhancement to assess diffuse fibrosis.19F magnetic resonance has recently emerged as a promising technique for the assessment of inflammation. In the following review we will discuss the basic aspects of fibrosis assessment with MR and its utility for diagnostic and prognostic evaluation. We will also address the topic of cardiovascular inflammation imaging with19F as a potential new development that may broaden the indications for MR in the future.

25

Butorov, Ekaterina A., and Olga V. Stukalova. "Role of cardiac MRI in the diagnosis of cardiac amyloidosis. Clinical cases." Clinical review for general practice 2, no. 2 (March 1, 2021): 16–20. http://dx.doi.org/10.47407/kr2021.2.2.00037.

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Purpose. The aim of this work is to show the capabilities of late gadolinium enhancement cardiac magnetic resonance imaging (MRI) in the diagnosis of a rare disease such as cardiac amyloidosis. Materials and methods. Demonstration of clinical cases detecting cardiac amyloidosis using MRI. Results. Contrast-enhanced cardiac MRI revealed patterns characteristic of cardiac amyloidosis. Conclusion. Cardiac MRI with late gadloinium enhancement is the method of choice in the diagnosis of cardiac amyloidosis.

26

Jun, B. C., K. H. Chang, S. J. Lee, and Y. S. Park. "Clinical feasibility of temporal bone magnetic resonance imaging as a prognostic tool in idiopathic acute facial palsy." Journal of Laryngology & Otology 126, no. 9 (July 12, 2012): 893–96. http://dx.doi.org/10.1017/s0022215112001417.

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AbstractObjective:To assess the feasibility of temporal bone magnetic resonance imaging for evaluating the severity and prognosis of idiopathic acute facial nerve palsy.Methods:Forty-four patients with idiopathic acute facial nerve palsy who had undergone gadolinium-enhanced magnetic resonance imaging were selected retrospectively. The degree of radiological facial nerve enhancement was determined using quantitative analysis (with region-of-interest measurements for separate facial nerve segments) and using subjective visual analysis. The clinical severity of facial nerve palsy was then correlated with the degree of facial nerve enhancement.Results:The visually determined degree of facial nerve enhancement did not correlate significantly with the House–Brackmann grade at either the early or late stages (p > 0.05). Results using the region-of-interest system were similar (p > 0.05).Conclusion:Temporal bone magnetic resonance imaging is not essential for patients with acute facial nerve palsy.

27

De Stefano, Domenico, Federica Vaccarino, Domiziana Santucci, Marco Parillo, Antonio Nenna, Francesco Loreni, Chiara Ferrisi, et al. "Delayed Enhancement in Cardiac CT: A Potential Alternative to Cardiac MRI? Technical Updates and Clinical Considerations." Applied Sciences 14, no. 10 (May 17, 2024): 4275. http://dx.doi.org/10.3390/app14104275.

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Despite cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) being the current gold standard for non-invasive myocardial characterization and fibrosis quantification, its accessibility is limited, particularly in acute settings and in certain patient populations with contraindications to magnetic resonance imaging. Late iodine enhancement (LIE) in computed tomography (CT) imaging has emerged as a potential alternative, capitalizing on the similarities in the contrast kinetics between gadolinium and iodinated contrast agents. Studies have investigated LIE-CT’s effectiveness in myocardial infarction (MI) detection, revealing promising outcomes alongside some disparities compared to LGE-CMR. LIE-CT also proves beneficial in diagnosing non-ischemic heart diseases such as myocarditis, hypertrophic cardiomyopathy, and sarcoidosis. While LIE-CT demonstrates good accuracy in detecting certain myocardial pathologies, including acute MI and chronic fibrotic changes, it has limitations, such as the inability to detect diffuse myocardial enhancement. Nonetheless, thanks to the availability of optimized protocols with minimal radiation doses and contrast medium administration, integrating LIE-CT into cardiac CT protocols could enhance its clinical utility, particularly in acute settings, providing valuable prognostic and management insights across a spectrum of cardiac ischemic and non-ischemic conditions.

28

Guglielmo, Marco, and Gianluca Pontone. "Clinical implications of cardiac magnetic resonance imaging fibrosis." European Heart Journal Supplements 24, Supplement_I (November 12, 2022): I123—I126. http://dx.doi.org/10.1093/eurheartjsupp/suac085.

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Abstract Cardiac magnetic resonance (CMR) is a non-invasive imaging method that allows to characterize myocardial tissue. In particular, using the late gadolinium enhancement technique, it is possible to identify areas of focal fibrosis. Specific distribution patterns of this fibrosis allow us to distinguish ischaemic cardiomyopathy (iCMP) from non-ischaemic cardiomyopathy (nCMP) and sometimes to identify the aetiology of the latter. Diffuse fibrosis can also be identified using the parametric T1 mapping sequences. For this purpose, the native T1 of the tissue is measured before the administration of the contrast agent (c.a.) or the extracellular volume is calculated after c.a. Both focal and diffuse fibrosis evaluated with CMR appear to be strong prognostic predictors for the identification of threatening ventricular arrhythmias and sudden cardiac death. These evidence open the doors to a possible role of CMR in the selection of the patient to be sent to a defibrillator implant in primary prevention. In this review, we will briefly review the techniques used in CMR for the evaluation of fibrosis. We will then focus on the clinical role of myocardial tissue fibrosis detection in iCMP and nCMP.

29

Wysocki, Andrzej, Pawel Gac, Rafal Poreba, Monika Michalek-zrabkowska, Krzysztof Kraik, Malgorzata Poreba, Helena Martynowicz, et al. "THE IMPORTANCE OF CARDIAC MAGNETIC RESONANCE IMAGING IN THE ASSESSMENT OF THE RISK OF CARDIAC ARRHYTHMIAS IN PATIENTS WITH ARTERIAL HYPERTENSION." Journal of Hypertension 42, Suppl 1 (May 2024): e29. http://dx.doi.org/10.1097/01.hjh.0001019572.68439.d5.

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Objective: Arterial hypertension leads to organ changes, including left ventricular hypertrophy. The increased mass of left ventricle increases the risk of cardiac arrhythmias, which enhances the risk of sudden cardiac death. Cardiac magnetic resonance imaging (CMRI) can identify the presence of myocardial fibrosis by assessing late gadolinium enhancement (LGE). The aim of the study was to assess the relationship between the presence of late gadolinium enhancement at the right ventricular insertion point (RVIP) determined by CMRI and the occurrence of cardiac arrhythmias in patients with arterial hypertension. Design and method: 30 patients with essential hypertension were qualified for the study, 18 men and 12 women, the average age of the subjects was 55.5 ± 12.4 years. All subjects underwent cardiac magnetic resonance imaging and 24-hour Holter ECG monitoring. Based on the presence of LGE at the right ventricular insertion point, assessed by CMRI, the subjects were divided into two subgroups. The first subgroup consisted of subjects with LGE at the right ventricular insertion point (RVIP + subgroup), while the second subgroup consisted of subjects without LGE at the right ventricular insertion point (RVIP - subgroup). Results: Subjects with LGE at the right ventricular insertion point were characterized by higher maximum and minimum heart rates in 24-hour Holter ECG recordings compared to subjects without LGE at the right ventricular insertion point (p < 0.05). In subjects with LGE at the right ventricular insertion point, Holter ECG evaluation revealed a statistically significantly higher number of single premature supraventricular beats, single premature ventricular beats and supraventricular tachycardias compared to subjects without LGE at the right ventricular insertion point (p < 0.05). The regression analysis performed showed that a longer time from the diagnosis of hypertension and the occurrence of LGE at the right ventricular insertion point assessed using CMRI are independent risk factors for cardiac arrhythmias (p < 0.05). Conclusions: Cardiac magnetic resonance imaging by identifying of late gadolinium enhancement at the right ventricular insertion point may be a useful diagnostic method in assessing the risk of cardiac arrhythmias in a group of patients with arterial hypertension.

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Cojan Minzat, Bianca Olivia, Carmen Cionca, Isabella Mihalcea, Silvia Lupu, and Lucia Agoston-Coldea. "Clinical utility of echocardiography and magnetic resonance imaging for detecting cardiac complications in Systemic Sclerosis. A case report." Medical Ultrasonography 17, no. 2 (June 1, 2015): 262. http://dx.doi.org/10.11152/mu.2013.2066.172.syss.

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Systemic sclerosis (SSc) is a chronic autoimmune disease that, beside skin involvement, may affect peripheral vessels and several organs, such as the lungs, kidneys or heart. Cardiac impairment usually becomes symptomatic in the late stages of the disease and is associated with poor prognosis. We report the case of a 80-year-old woman presenting with symptoms of heart failure, subsequently diagnosed with limited SSc. Cardiac function was evaluated using a combined approach based on echocardiography and cardiac magnetic resonance imaging with late gadolinium enhancement. This case shows that the late diagnosis of SSc may have fatal consequences.

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Tan, Sarah Ming Li, Ching Ching Ong, Kong Bing Tan, Hui-Lin Chin, Prakash R. Paliwal, Kay Wei Ping Ng, and Weiqin Lin. "Subclinical Cardiomyopathy in Miyoshi Myopathy Detected by Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging." International Heart Journal 62, no. 1 (January 30, 2021): 186–92. http://dx.doi.org/10.1536/ihj.20-354.

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Niida, Tomiharu, Kikuo Isoda, Makoto Sasaki, Masahiro Horikawa, Katsumi Hayashi, and Fumitaka Ohsuzu. "Late Gadolinium Enhanced High Resolution Magnetic Resonance Imaging Reveals Pathophysiological Condition of Cardiac Sarcoidosis." International Heart Journal 50, no. 2 (2009): 263–66. http://dx.doi.org/10.1536/ihj.50.263.

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Bonura, Erica, Mahmoud Abdelsalam, Martijn Bos, Philip Araoz, Steve Ommen, Michael Ackerman, and Jeffrey Geske. "LATE GADOLINIUM ENHANCEMENT ON CARDIAC MAGNETIC RESONANCE IMAGING IN HYPERTROPHIC CARDIOMYOPATHY OF THE YOUNG." Journal of the American College of Cardiology 71, no. 11 (March 2018): A1643. http://dx.doi.org/10.1016/s0735-1097(18)32184-3.

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Stirrat, John, and James A. White. "The Prognostic Role of Late Gadolinium Enhancement Magnetic Resonance Imaging in Patients With Cardiomyopathy." Canadian Journal of Cardiology 29, no. 3 (March 2013): 329–36. http://dx.doi.org/10.1016/j.cjca.2012.11.033.

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Károlyi, Mihály, Justyna M. Sokolska, Malgorzata Polacin, Lucas Weber, Hatem Alkadhi, and Robert Manka. "Optimizing Late Gadolinium Enhancement Assessment with Cardiovascular Magnetic Resonance Imaging in Myocarditis Follow-up." Journal of Cardiovascular Magnetic Resonance 26 (2024): 100913. http://dx.doi.org/10.1016/j.jocmr.2024.100913.

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Szabo, Liliana, Giulia Brunetti, Alberto Cipriani, Vencel Juhasz, Francesca Graziano, Kristof Hirschberg, Zsofia Dohy, et al. "Certainties and Uncertainties of Cardiac Magnetic Resonance Imaging in Athletes." Journal of Cardiovascular Development and Disease 9, no. 10 (October 20, 2022): 361. http://dx.doi.org/10.3390/jcdd9100361.

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Prolonged and intensive exercise induces remodeling of all four cardiac chambers, a physiological process which is coined as the “athlete’s heart”. This cardiac adaptation, however, shows overlapping features with non-ischemic cardiomyopathies, such as dilated, arrhythmogenic and hypertrophic cardiomyopathy, also associated with athlete’s sudden cardiac death. Cardiac magnetic resonance (CMR) is a well-suited, highly reproducible imaging modality that can help differentiate athlete’s heart from cardiomyopathy. CMR allows accurate characterization of the morphology and function of cardiac chambers, providing full coverage of the ventricles. Moreover, it permits an in-depth understanding of the myocardial changes through specific techniques such as mapping or late gadolinium enhancement. In this narrative review, we will focus on the certainties and uncertainties of the role of CMR in sports cardiology. The main aspects of physiological adaptation due to regular and intensive sports activity and the application of CMR in highly trained athletes will be summarized.

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O’Neill, S. G., S. Woldman, F. Bailliard, W. Norman, J. McEwan, D. A. Isenberg, A. M. Taylor, and A. Rahman. "Cardiac magnetic resonance imaging in patients with systemic lupus erythematosus." Annals of the Rheumatic Diseases 68, no. 9 (November 26, 2008): 1478–81. http://dx.doi.org/10.1136/ard.2008.098053.

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Objectives:To delineate the cardiac magnetic resonance (MR) appearances of cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE), in comparison with transthoracic echocardiographs.Methods:Cardiac MR was performed on 22 patients with SLE—11 with previous CVD and 11 matched controls—using late gadolinium contrast enhancement (LGE) to identify areas of myocardial scarring; Transthoracic echocardiography (TTE) was performed on the same day.Results:Twenty female and two male patients participated. LGE was seen in 5/11 subjects in the CVD group (4/5 with previous myocardial infarction) and 1/11 in the control group. TTE detected myocardial abnormalities in 2/6 patients with LGE.Conclusion:The cardiac MR appearance of CVD in these patients with SLE was suggestive of coronary disease, rather than cumulative inflammatory muscle damage. Cardiac MR detected more abnormalities than TTE. Further studies of cardiac MR in patients with SLE are warranted to investigate these preliminary findings.

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Lossnitzer, Dirk, Henning Steen, Alexandra Zahn, Stephanie Lehrke, Celine Weiss, Karl Weiss, Evangelos Giannitsis, et al. "Myocardial late gadolinium enhancement cardiovascular magnetic resonance in patients with cirrhosis." Journal of Cardiovascular Magnetic Resonance 12, no. 1 (2010): 47. http://dx.doi.org/10.1186/1532-429x-12-47.

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Huang, Y. Jessica, Alexis Harrison, Vikren Sarkar, Prema Rassiah-Szegedi, Hui Zhao, Martin Szegedi, Long Huang, Brent Wilson, David K. Gaffney, and Bill J. Salter. "Detection of late radiation damage on left atrial fibrosis using cardiac late gadolinium enhancement magnetic resonance imaging." Advances in Radiation Oncology 1, no. 2 (April 2016): 106–14. http://dx.doi.org/10.1016/j.adro.2016.04.002.

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Massoud, Ikram, Nader Botros, Atef Yehia, Hassan Abdelghafoor, Mohamed Donya, Ahmd Samir, Heba Serag, and Elham Mohamed. "Restrictive right ventricular performance assessed by cardiac magnetic resonance after balloon valvuloplasty of critical pulmonary valve stenosis." Cardiology in the Young 26, no. 3 (June 22, 2015): 556–68. http://dx.doi.org/10.1017/s1047951115000724.

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AbstractBackgroundLittle data are published about right ventricular diastolic performance in patients with critical pulmonary valve stenosis after balloon pulmonary valvuloplasty thus far.MethodsA total of 44 patients with isolated critical pulmonary valve stenosis who had undergone balloon valvuloplasty with haemodynamic recordings were enrolled to the study; 33 patients who came for follow-up underwent further imaging by echocardiography after 6 months and their right ventricular functional parameters were compared with 33 control patients of the same age and sex. Out of 33 patients, 21 underwent cardiac MRI with late gadolinium enhancement to assess the presence of right ventricular fibrosis.ResultsThe right ventricular systolic pressure (p<0.0001) and right ventricular outflow tract gradient (p<0.0001) decreased acutely (p<0.0001) after balloon valvuloplasty. During follow-up, M-mode left ventricular end diastolic dimension (p<0.001) and end systolic dimension increased (p<0.001), whereas right ventricular end diastolic dimension decreased (p<0.001). Compared with controls, patients (n=33) had significantly reduced tricuspid annular Ea and higher E/Ea (p<0.001). Right ventricular systolic dysfunction was also suggested by reduced tricuspid annular systolic velocity (p<0.001). Late gadolinium enhancement was demonstrated in 13 out of 21 patients with restrictive physiology, which involves the anterior right ventricular outflow tract, anterior wall, and inferior wall. The right ventricular late gadolinium enhancement score correlated positively with age (r=0.7, p<0.001) and right ventricular mass index (r=0.52, p<0.001).ConclusionThe persistence of right ventricular diastolic dysfunction after relief of chronic pressure overload of critical pulmonary valve stenosis suggests that a factor – other than increase in afterload – is involved in this physiology. Fibrosis is the most likely factor responsible for persistence of restrictive physiology as documented by late gadolinium enhancement.

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Tsampasian, Vasiliki, Sandeep S. Hothi, Thuwarahan Ravindrarajah, Andrew J. Swift, Pankaj Garg, and Vassilios S. Vassiliou. "Valvular Cardiomyopathy: The Value of Cardiovascular Magnetic Resonance Imaging." Cardiology Research and Practice 2022 (February 22, 2022): 1–9. http://dx.doi.org/10.1155/2022/3144386.

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Cardiovascular magnetic resonance (CMR) imaging has had a vast impact on the understanding of a wide range of disease processes and pathophysiological mechanisms. More recently, it has contributed significantly to the diagnosis and risk stratification of patients with valvular heart disease. With its increasing use, CMR allows for a detailed, reproducible, qualitative, and quantitative evaluation of left ventricular volumes and mass, thereby enabling assessment of the haemodynamic impact of a valvular lesion upon the myocardium. Postprocessing of the routinely acquired images with feature tracking CMR methodology can give invaluable information about myocardial deformation and strain parameters that suggest subclinical ventricular impairment that remains undetected by conventional measures such as the ejection fraction (EF). T1 mapping and late gadolinium enhancement (LGE) imaging provide deep myocardial tissue characterisation that is changing the approach towards risk stratification of patients as an increasing body of evidence suggests that the presence of fibrosis is related to adverse events and prognosis. This review summarises the current evidence regarding the utility of CMR in the left ventricular assessment of patients with aortic stenosis or mitral regurgitation and its value in diagnosis, risk stratification, and management.

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Deva, Djeven P., Felipe S. Torres, Rachel M. Wald, S. Lucy Roche, Laura Jimenez-Juan, Erwin N. Oechslin, and Andrew M. Crean. "The value of stress perfusion cardiovascular magnetic resonance imaging for patients referred from the adult congenital heart disease clinic: 5-year experience at the Toronto General Hospital." Cardiology in the Young 24, no. 5 (September 18, 2013): 822–30. http://dx.doi.org/10.1017/s104795111300111x.

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AbstractBackground: Vasodilator stress perfusion cardiovascular magnetic resonance imaging is a clinically useful tool for detection of clinically significant myocardial ischaemia in adults. We report our 5-year retrospective experience with perfusion cardiovascular magnetic resonance in a large, quarternary adult congenital heart disease centre. Methods: We reviewed all cases of perfusion cardiovascular magnetic resonance in patients referred from the adult congenital heart disease service. Dipyridamole stress perfusion cardiovascular magnetic resonance was undertaken on commercially available 1.5 and 3 T cardiovascular magnetic resonance scanners. Late gadolinium enhancement imaging was performed 8–10 minutes after completion of the rest perfusion sequence. Navigator whole-heart coronary magnetic resonance angiography was also performed where feasible. Results of stress cardiovascular magnetic resonance were correlated with complementary imaging studies, surgery, and clinical outcomes. Results: Over 5 years, we performed 34 stress perfusion cardiovascular magnetic resonance examinations (11 positive). In all, 84% of patients had further investigations for ischaemia in addition to cardiovascular magnetic resonance. Within a subgroup of 19 patients who had definitive alternative assessment of their coronary arteries, stress perfusion cardiovascular magnetic resonance demonstrated a sensitivity of 82% and specificity of 100%. Of the 34 studies, two were false negatives, in which the aetiology of ischaemia was extrinsic arterial compression rather than intrinsic coronary luminal narrowing. Coronary abnormalities were identified in 71% of cases who had coronary magnetic resonance angiography. Conclusion: Stress perfusion cardiovascular magnetic resonance is a useful and accurate tool for investigation of myocardial ischaemia in an adult congenital heart disease population with suspected non-atherosclerotic coronary abnormalities.

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Bazoukis, George, Stamatis S. Papadatos, Archontoula Michelongona, Konstantinos Lampropoulos, Dimitrios Farmakis, and Vassilis Vassiliou. "Contemporary Role of Cardiac Magnetic Resonance in the Management of Patients with Suspected or Known Coronary Artery Disease." Medicina 57, no. 7 (June 24, 2021): 649. http://dx.doi.org/10.3390/medicina57070649.

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Cardiac magnetic resonance imaging (CMR) is a useful non-invasive radiation-free imaging modality for the management of patients with coronary artery disease (CAD). CMR cine imaging provides the “gold standard” assessment of ventricular function, late gadolinium enhancement (LGE) provides useful data for the diagnosis and extent of myocardial scar and viability, while stress imaging is an established technique for the detection of myocardial perfusion defects indicating ischemia. Beyond its role in the diagnosis of CAD, CMR allows accurate risk stratification of patients with established CAD. This review aims to summarize the data regarding the role of CMR in the contemporary management of patients with suspected or known coronary artery disease.

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Pique, J., F. Bonneville, D. Brassat, D. Peaureaux, M. Benaiteau, H. Dumas, N. Fabre, M. Clanet, and D. Biotti. "Peripheral late reactivation of a previously typical monofocal Baló’s concentric sclerosis lesion." Multiple Sclerosis Journal 21, no. 8 (May 26, 2015): 1080–83. http://dx.doi.org/10.1177/1352458515586087.

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We report a 41-year-old woman with rapidly progressive left hemiparesis, revealing an inflammatory reactivation of a previously known parietal Baló’s concentric sclerosis lesion. The first attack occurred five years before. After a slow recovery following high-dose steroid infusions the patient stabilized. Because of recurrent ataxia and left hemiparesis a new magnetic resonance imaging was performed showing an extension of the initial lesion with a peripheral gadolinium enhancement on T1-weighted images. Such a reactivation pattern of an isolated Baló’s concentric sclerosis lesion, occurring some years later, is described for the first time.

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Bhalodiya, Jayendra Maganbhai, Arnab Palit, Gerard Giblin, Manoj Kumar Tiwari, Sanjay K. Prasad, Sunil K. Bhudia, Theodoros N. Arvanitis, and Mark A. Williams. "Identifying Myocardial Infarction Using Hierarchical Template Matching–Based Myocardial Strain: Algorithm Development and Usability Study." JMIR Medical Informatics 9, no. 2 (February 10, 2021): e22164. http://dx.doi.org/10.2196/22164.

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Background Myocardial infarction (MI; location and extent of infarction) can be determined by late enhancement cardiac magnetic resonance (CMR) imaging, which requires the injection of a potentially harmful gadolinium-based contrast agent (GBCA). Alternatively, emerging research in the area of myocardial strain has shown potential to identify MI using strain values. Objective This study aims to identify the location of MI by developing an applied algorithmic method of circumferential strain (CS) values, which are derived through a novel hierarchical template matching (HTM) method. Methods HTM-based CS H-spread from end-diastole to end-systole was used to develop an applied method. Grid-tagging magnetic resonance imaging was used to calculate strain values in the left ventricular (LV) myocardium, followed by the 16-segment American Heart Association model. The data set was used with k-fold cross-validation to estimate the percentage reduction of H-spread among infarcted and noninfarcted LV segments. A total of 43 participants (38 MI and 5 healthy) who underwent CMR imaging were retrospectively selected. Infarcted segments detected by using this method were validated by comparison with late enhancement CMR, and the diagnostic performance of the applied algorithmic method was evaluated with a receiver operating characteristic curve test. Results The H-spread of the CS was reduced in infarcted segments compared with noninfarcted segments of the LV. The reductions were 30% in basal segments, 30% in midventricular segments, and 20% in apical LV segments. The diagnostic accuracy of detection, using the reported method, was represented by area under the curve values, which were 0.85, 0.82, and 0.87 for basal, midventricular, and apical slices, respectively, demonstrating good agreement with the late-gadolinium enhancement–based detections. Conclusions The proposed applied algorithmic method has the potential to accurately identify the location of infarcted LV segments without the administration of late-gadolinium enhancement. Such an approach adds the potential to safely identify MI, potentially reduce patient scanning time, and extend the utility of CMR in patients who are contraindicated for the use of GBCA.

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Ganigara, Madhusudan, Bharti Sharma, RaviBabu Komalla, SumanY Vyas, Gopichand Mannam, and NitinKrishna Rao. "Unique pattern of late gadolinium enhancement on cardiac magnetic resonance imaging in Duchenne muscular dystrophy." Annals of Pediatric Cardiology 9, no. 2 (2016): 190. http://dx.doi.org/10.4103/0974-2069.181496.

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Akita, Tomomi, Kunihiko Kiuchi, Koji Fukuzawa, Akira Shimane, Sonoko Matsuyama, Mitsuru Takami, Jun Kurose, et al. "Lesion distribution after cryoballoon ablation and hotballoon ablation: Late‐gadolinium enhancement magnetic resonance imaging analysis." Journal of Cardiovascular Electrophysiology 30, no. 10 (July 23, 2019): 1830–40. http://dx.doi.org/10.1111/jce.14073.

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Sun, Yibo, Dongdong Deng, Liping Sun, Yi He, Hui Wang, and Jianzeng Dong. "Comparison of Segmentation Algorithms for Detecting Myocardial Infarction Using Late Gadolinium Enhancement Magnetic Resonance Imaging." Cardiovascular Innovations and Applications 5, no. 2 (November 1, 2020): 89–95. http://dx.doi.org/10.15212/cvia.2019.0574.

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Objective: The aim of this study was to validate the accuracy of a new automatic method for scar segmentation and compare its performance with that of two other frequently used segmentation algorithms.Methods: Twenty-six late gadolinium enhancement cardiovascular magnetic resonance images of diseased hearts were segmented by the full width at half maximum (FWHM) method, the n standard deviations (nSD) method, and our new automatic method. The results of the three methods were compared with the consensus ground truth obtained by manual segmentation of the ventricular boundaries.Results: Our automatic method yielded the highest Dice score and the lowest volume difference compared with the consensus ground truth segmentation. The nSD method produced large variations in the Dice score and the volume difference. The FWHM method yielded the lowest Dice score and the greatest volume difference compared with the automatic, 6SD, and 8SD methods, but resulted in less variation when different observers segmented the images.Conclusion: The automatic method introduced in this study is highly reproducible and objective. Because it requires no manual intervention, it may be useful for processing large datasets produced in clinical applications.

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Birkemeyer, R., R. Toelg, U. Zeymer, R. Wessely, S. Jackle, B. Hairedini, M. Lubke, M. Assfalg, and W. Jung. "Comparison of cardiogoniometry and electrocardiography with perfusion cardiac magnetic resonance imaging and late gadolinium enhancement." Europace 14, no. 12 (July 11, 2012): 1793–98. http://dx.doi.org/10.1093/europace/eus218.

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Hen, Yasuki, Nobuo Iguchi, Yuko Utanohara, Kaori Takada, Haruhiko Machida, Ayako Takara, Kunihiko Teraoka, et al. "Extent of Late Gadolinium Enhancement on Cardiac Magnetic Resonance Imaging in Japanese Hypertrophic Cardiomyopathy Patients." Circulation Journal 80, no. 4 (2016): 950–57. http://dx.doi.org/10.1253/circj.cj-15-1100.

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