Готові списки джерел за темами / Lactucine

Добірка наукової літератури з теми "Lactucine"

Автор: Grafiati
Опубліковано: 7 липня 2024
Оновлено: 7 липня 2024

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Зміст

  1. Статті в журналах
  2. Дисертації
  3. Книги
  4. Частини книг
  5. Тези доповідей конференцій

Статті в журналах з теми "Lactucine":

1

Zidorn, Christian, Ernst-Peter Ellmerer, Werner Heller, Richard Greil, Manuela Guggenberger, Karl-Hans Ongania, and Hermann Stuppner. "A New Sesquiterpene Lactone Sulfate from Reichardia gaditana (Asteraceae)." Zeitschrift für Naturforschung B 62, no. 1 (January 1, 2007): 132–34. http://dx.doi.org/10.1515/znb-2007-0121.

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The new sesquiterpenoid 8-deoxy-15-(3′-hydroxy-2′-methyl-propanoyl)-lactucin 3′-sulfate (1) was isolated from the methanolic extract of roots of Reichardia gaditana L. The compound was isolated by silica gel column chromatography (CC) and repeated Sephadex LH-20 CC. Structure elucidation was accomplished by high-resolution mass spectrometry and by 1D- and 2D-NMR spectroscopy. The chemosystematic significance of the new compound is discussed in the context of sesquiterpenoids from other members of the Lactuceae tribe of the Asteraceae family.
2

Wang, Xin, Min Liu, Guo He Cai, Yan Chen, Xiao Chen Shi, Cong Cong Zhang, Bo Xia, et al. "A Potential Nutraceutical Candidate Lactucin Inhibits Adipogenesis through Downregulation of JAK2/STAT3 Signaling Pathway-Mediated Mitotic Clonal Expansion." Cells 9, no. 2 (January 31, 2020): 331. http://dx.doi.org/10.3390/cells9020331.

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The prevalence of obesity has increased dramatically worldwide in the past ~50 years. Searching for safe and effective anti-obesity strategies are urgently needed. Lactucin, a plant-derived natural small molecule, is known for anti-malaria and anti-hyperalgesia. The study is to investigate whether lactucin plays a key role in adipogenesis. To this end, in vivo male C57BL/6 mice fed a high-fat diet (HFD) were treated with 20 mg/kg/day of lactucin or vehicle by gavage for seven weeks. Compared with vehicle-treated controls, Lactucin-treated mice showed lower body mass and mass of adipose tissue. Consistently, in vitro 3T3-L1 cells were treated with 20 μM of lactucin. Compared to controls, lactucin-treated cells showed significantly less lipid accumulation during adipocyte differentiation and lower levels of lipid synthesis markers. Mechanistically, we showed the anti-adipogenic property of lactucin was largely limited to the early stage of adipogenesis. Lactucin-treated cells fail to undergo mitotic clonal expansion (MCE). Further studies demonstrate that lactucin-induced MCE arrests might result from reduced phosphorylation of JAK2 and STAT3. We then asked whether activation of JAK2/STAT3 would restore the inhibitory effect of lactucin on adipogenesis with pharmacological STAT3 activator colivelin. Our results revealed similar levels of lipid accumulation between lactucin-treated cells and controls in the presence of colivelin, indicating that inactivation of STAT3 is the limiting factor for the anti-adipogenesis of lactucin in these cells. Together, our results provide the indication that lactucin exerts an anti-adipogenesis effect, which may open new therapeutic options for obesity.
3

Imam, Khandaker Md Sharif Uddin, Yu Tian, Fengjiao Xin, Yingying Xie, and Boting Wen. "Lactucin, A Bitter Sesquiterpene from Cichorium intybus, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway." Molecules 27, no. 21 (October 29, 2022): 7358. http://dx.doi.org/10.3390/molecules27217358.

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Lung cancer, especially adenocarcinoma, is the second most occurring and highest fatality-causing cancer worldwide. Many natural anticancer compounds, such as sesquiterpene lactones (SLs), show promising anticancer properties. Herein, we examined Lactucin, an SL from the plant Cichorium intybus, for its cytotoxicity, apoptotic-inducing, cell cycle inhibiting capacity, and associated protein expression. We also constructed a biotinylated Lactucin probe to isolate interacting proteins and identified them. We found that Lactucin stops the proliferation of A549 and H2347 lung adenocarcinoma cell lines while not affecting normal lung cell MRC5. It also significantly inhibits the cell cycle at G0/G1 stage and induces apoptosis. The western blot analysis shows that Lactucin downregulates the MAPK pathway, cyclin, and cyclin-dependent kinases, inhibiting DNA repair while upregulating p53, p21, Bax, PTEN, and downregulation of Bcl-2. An increased p53 in response to DNA damage upregulates p21, Bax, and PTEN. In an activity-based protein profiling (ABPP) analysis of A549 cell’s protein lysate using a biotinylated Lactucin probe, we found that Lactucin binds PGM, PKM, and LDHA PDH, four critical enzymes in central carbon metabolism in cancer cells, limiting cancer cells in its growth; thus, Lactucin inhibits cancer cell proliferation by downregulating the MAPK and the Central Carbon Metabolism pathway.
4

Zheleva-Dimitrova, Dimitrina, Alexandra Petrova, Gokhan Zengin, Kouadio Ibrahime Sinan, Vessela Balabanova, Olivier Joubert, Christian Zidorn, Yulian Voynikov, Rumyana Simeonova, and Reneta Gevrenova. "Metabolite profiling and bioactivity of Cicerbita alpina (L.) Wallr. (Asteraceae, Cichorieae)." Plants 12, no. 5 (February 23, 2023): 1009. http://dx.doi.org/10.3390/plants12051009.

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Cicerbita alpina (L.) Wallr. is a perennial herbaceous plant in the tribe Cichorieae (Lactuceae), Asteraceae family, distributed in the mountainous regions in Europe. In this study, we focused on the metabolite profiling and the bioactivity of C. alpina leaves and flowering heads methanol-aqueous extracts. The antioxidant activity of extracts, as well as inhibitory potential towards selected enzymes, involving in several human diseases, including metabolic syndrome (α-glucosidase, α-amylase, and lipase), Alzheimer’s disease, (cholinesterases: AChE, BchE), hyperpigmentation (tyrosinase), and cytotoxicity were assessed. The workflow comprised ultra-high-performance liquid chromatography—high-resolution mass spectrometry (UHPLC-HRMS). UHPLC-HRMS analysis revealed more than 100 secondary metabolites, including acylquinic, acyltartaric acids, flavonoids, bitter sesquiterpene lactones (STLs), such as lactucin, dihydrolactucin, their derivatives, and coumarins. Leaves showed a stronger antioxidant activity compared to flowering heads, as well as lipase (4.75 ± 0.21 mg OE/g), AchE (1.98 ± 0.02 mg GALAE/g), BchE (0.74 ± 0.06 mg GALAE/g), and tyrosinase (49.87 ± 3.19 mg KAE/g) inhibitory potential. Flowering heads showed the highest activity against α-glucosidase (1.05 ± 0.17 mmol ACAE/g) and α-amylase (0.47 ± 0.03). The obtained results highlighted C. alpina as a rich source of acylquinic, acyltartaric acids, flavonoids, and STLs with significant bioactivity, and therefore the taxon could be considered as a potential candidate for the development of health-promoting applications.
5

Zhang, Fu-Hua, Yu-Ling Yan, Ying Wang, and Zhen Liu. "Lactucin induces potent anti-cancer effects in HL-60 human leukemia cancer cells by inducing apoptosis and sub-G1 cell cycle arrest." Bangladesh Journal of Pharmacology 11, no. 2 (April 15, 2016): 478. http://dx.doi.org/10.3329/bjp.v11i2.26729.

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<p class="Abstract">The main purpose of the present study was to examine the antitumor and apoptotic effects of lactucin in HL-60 human leukemia cancer cells. MTT assay was used to examine the cytotoxic effects of lactucin while as phase contrast, fluorescence and transmission electron microscopy techniques were used to evaluate the apoptotic effects of lactucin in these cells. Flow cytometry was used to assess the effects of lactucin on cell cycle phase distribution. The results indicate that lactucin induced potent, time– and dose-dependent antitumor effects. The microscopic techniques showed that lactucin induced characteristic features of apoptosis including cell shrinkage, membrane blebbing, appearance of vacuoles, swelling of mitochondria and endoplasmic reticulum. Viable cells are stained green, early apoptotic cells are stained yellow, while as late apoptotic cells are stained reddish orange. Flow cytometry revealed that lactucin induced sub-G1 cell cycle arrest.</p><p class="Abstract"><strong>Video Clips</strong></p><p class="Abstract">Phase contrast microscopy: <a href="https://www.youtube.com/v/xrTjOVvlTxQ">1</a> <a href="https://www.youtube.com/v/GxuMkGnkpSE">2</a> <a href="https://www.youtube.com/v/SfmdL2-O45Y">3</a> <a href="https://www.youtube.com/v/7vbJ9HMRTHU">4</a> <a href="https://www.youtube.com/v/u4aLzmlXF8s">5</a> <a href="https://www.youtube.com/v/ucl8DjPeV9c">6</a> <a href="https://www.youtube.com/v/uI932TJVfFY">7</a> <a href="https://www.youtube.com/v/5sMlUKbKMhc">8</a> <a href="https://www.youtube.com/v/-tx20gFHYnc">9</a></p><p> </p>
6

Kisiel, Wanda, and Klaudia Michalska. "Root Constituents of Cichorium pumilum and Rearrangements of Some Lactucin-like Guaianolides." Zeitschrift für Naturforschung C 58, no. 11-12 (December 1, 2003): 789–92. http://dx.doi.org/10.1515/znc-2003-11-1206.

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Abstract Two eudesmanolides, eight lactucin-like guaianolides and five phenolic compounds were isolated for the first time from roots of Cichorium pumilum, along with two previously reported eudesmane-type sesquiterpene lactones. Rearrangements of some lactucin-like guaianolides during isolation procedures were also discussed.
7

van Herwijnen, Z. O., and J. C. Manning. "A review of the history and taxonomy of the enigmatic southern African endemic wild lettuce Lactuca dregeana DC. (Asteraceae: Lactuceae: Lactucinae)." South African Journal of Botany 108 (January 2017): 352–58. http://dx.doi.org/10.1016/j.sajb.2016.08.016.

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8

Peters, Angeline M., and Aart van Amerongen. "Relationship between Levels of Sesquiterpene Lactones in Chicory and Sensory Evaluation." Journal of the American Society for Horticultural Science 123, no. 2 (March 1998): 326–29. http://dx.doi.org/10.21273/jashs.123.2.326.

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In this pilot study, we investigated the relationship between levels of bitter sesquiterpene lactones and sensory evaluation of chicory (Cichorium intybus L.). The levels of two bitter sesquiterpene lactones—lactucopicrin and lactucin-like sesquiterpene lactones—were measured by ELISA in raw and cooked chicory samples from several cultivars. Data were compared with the results of a sensory evaluation on the flavor attributes bitterness, typical chicory flavor, and total flavor intensity of identical chicory samples. Linear regression analysis demonstrated that the levels of lactucin-like sesquiterpene lactones were significantly related to bitterness (P = 0.006) and total flavor intensity (P = 0.03) attributes in raw chicory samples. When cooked chicory samples were evaluated, the levels of lactucin-like sesquiterpene lactones were significantly related to bitterness (P = 0.002), typical chicory flavor (P < 0.001), and total flavor intensity (P = 0.009) attributes, while lactucopicrin levels were related to bitterness (P = 0.002) only. These results show that the ELISA can be useful to predict flavor attributes in chicory.
9

Mbofung, Gladys Y., Soon Gyu Hong та Barry M. Pryor. "Phylogeny of Fusarium oxysporum f. sp. lactucae Inferred from Mitochondrial Small Subunit, Elongation Factor 1-α, and Nuclear Ribosomal Intergenic Spacer Sequence Data". Phytopathology® 97, № 1 (січень 2007): 87–98. http://dx.doi.org/10.1094/phyto-97-0087.

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Fusarium oxysporum f. sp. lactucae, causal agent of Fusarium wilt of lettuce, is a serious pathogen recently reported in Arizona. Sequence analysis of the mitochondrial small subunit (mtSSU), translation elongation factor 1-α (EF-1α) gene, and the nuclear ribosomal DNA intergenic spacer (IGS) region was conducted to resolve relationships among f. sp. lactucae isolates, F. oxysporum isolates from other hosts, and local non-pathogenic isolates. Analysis of mtSSU sequences provided limited phylogenetic resolution and did not differentiate the lactucae isolates from 13 other F. oxysporum isolates. Analysis of EF-1α sequences resulted in moderate resolution, grouping seven formae speciales with the lactucae isolates. Analysis of the IGS region revealed numerous sequence polymorphisms among F. oxysporum formae speciales consisting of insertions, deletions, and single nucleotide transitions and substitutions. Repeat sequence analysis revealed several duplicated subrepeat units that were distributed across much of the region. Based on analysis of the IGS sequence data, lactucae race 1 isolates resolved as a monophyletic group with three other formae speciales of F. oxysporum. In all analyses, lactucae race 2 isolates composed a separate lineage that was phylo-genetically distinct and distantly related to the lactucae race 1 isolates.
10

Wesołowska, A., A. Nikiforuk, K. Michalska, W. Kisiel, and E. Chojnacka-Wójcik. "Analgesic and sedative activities of lactucin and some lactucin-like guaianolides in mice." Journal of Ethnopharmacology 107, no. 2 (September 2006): 254–58. http://dx.doi.org/10.1016/j.jep.2006.03.003.

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Статті в журналах Дисертації

Дисертації з теми "Lactucine":

1

Ruggieri, Francesca. "Putting nature back into drug discovery : selection, design and synthesis of bioinspired chemical libraries for the discovery of new antibacterials." Electronic Thesis or Diss., Université de Lille (2022-....), 2024. http://www.theses.fr/2024ULILS013.

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Les produits naturels (PNs) ont perdu en popularité depuis l'introduction des petites molécules synthétiques il y a plusieurs années. De nombreuses raisons expliquent ce choix, telles que les difficultés d'accès et d'approvisionnement, la complexité de la chimie des PNs et l'avènement de la chimie combinatoire. Cependant, les PNs offrent de nombreuses propriétés intéressantes par rapport aux molécules synthétiques conventionnelles, ce qui leur confère à la fois des avantages et des inconvénients dans le contexte de la recherche de principes actifs. En général, les PNs se caractérisent par un plus grand nombre de carbones sp3 et de centres stéréogènes, une grande diversité de squelettes et une grande complexité structurelle. La moitié des médicaments approuvés par la FDA depuis 1994 étant des PNs ou des dérivés hémisynthétiques, et étant donnée la récente stagnation de la recherche et du développement de nouveaux médicaments, il devient de plus en plus évident que les produits naturels doivent être utilisés dans le processus de découverte de médicaments en tant que source d'inspiration.Par conséquent, de nombreuses stratégies émergent aujourd'hui pour la construction de chimiothèques inspirées par la nature, selon les stratégies "top-down" et "bottom-up". Dans les approches "bottom-up", la complexité est créée à partir de réactifs simples. En revanche, les approches "top-down" consistent à apporter des modifications structurelles à un produit naturel déjà complexe.Le travail présenté décrit deux approches différentes pour enrichir la chimiothèque de notre unité de recherche avec des composés dérivés de PNs. Une stratégie hémisynthétique "top-down" a été planifiée pour obtenir des dérivés de la lactucine et de la 11β,13-dihydrolactucine, deux lactones sesquiterpéniques extraites des racines de chicorée. 36 dérivés esters ont été synthétisés en trois étapes (synthèse classique), ainsi que deux bibliothèques de dérivés aminés (en utilisant la synthèse parallèle). Tous les composés ont ensuite été testés contre Mycobacterium tuberculosis et certaines molécules ont montré des activités prometteuses (CMI < 1,2 µM).D'autre part, une stratégie "bottom-up" a permis la synthèse de deux analogues de l'antibiotique naturel hygromycine A. Pour cette approche nous sommes partis de réactifs simples disponibles dans le commerce et avons appliqué une stratégie de déaromatisation dans le processus de synthèse.L'ensemble de ces travaux nous a permis d'explorer un espace chimique plus large, d'accroître la diversité structurelle de notre chimiothèque et de découvrir de nouveaux "hits". Nous pourrons également ainsi identifier de nouvelles cibles antibactériennes
Natural products (NPs) have declined in popularity since the introduction of synthetic small molecules several years ago. Many are the reasons behind this choice, such as difficulties in access and supply, complexities of NP chemistry and the advent of combinatorial chemistry. However, NPs offer many interesting properties compared to conventional synthetic molecules, which confer both advantages and challenges for the drug discovery process. Usually, NPs are characterized by a higher number of sp3 carbons and stereogenic centres, large scaffold diversity and structural complexity. With half of the drugs approved by the FDA since 1994 being NPs or hemisynthetic derivatives and the recent stagnation in new drug research and development, it is becoming more and more evident that NPs should be reintroduced in the drug discovery process as a source of inspiration.Therefore, many strategies are now emerging for the construction of nature-inspired chemical libraries, such as “top-down” and “bottom-up” strategies. In “bottom-up” approaches, complexity is created starting from simple building blocks. On the other hand, “top-down” approaches are assumed to make structural modifications to an already complex NP.Our presented work describes two different approaches to enrich the chemical library of our research unit with NP-derived compounds. A “top-down” semisynthetic strategy was planned to obtain derivatives of lactucin and 11β,13-dihydrolactucin, two sesquiterpene lactones extracted from chicory roots. Thirty-six ester derivatives were synthesized in three steps (classical synthesis), together with two amine derivative libraries (using parallel synthesis). All the compounds were then tested against Mycobacterium tuberculosis and some promising hits were found (MICGFP < 1.2 μM). On the other hand, a “bottom-up” strategy allowed the synthesis of two analogues of the known natural antibiotic hygromycin A. This approach started from simple commercially available building blocks and employed a dearomatization strategy in the synthetic process.Together, we explored a broader chemical space, increased the structural diversity of our chemical library and discovered new potential antibacterial hits. Moreover, this work paves the way for the discovery of new antibacterial targets
2

Tegel, Friedrich. "Die Testaepidermis der Lactuceae (Asteraceae) ihre Diversität und systematische Bedeutung /." Connect to this title online, 2002. http://edoc.ub.uni-muenchen.de/archive/00000104/.

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3

Tegel, Friedrich. "Die Testaepidermis der Lactuceae (Asteraceae) – ihre Diversität und systematische Bedeutung." Diss., lmu, 2002. http://nbn-resolving.de/urn:nbn:de:bvb:19-1043.

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4

Tchervenivanova, Eli. "Development of a model to predict sporulation of Bremia lactucae in lettuce." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=23943.

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The effect of temperature and duration of leaf wetness (DLW) on sporulation of Bremia lactucae was determined for lettuce cv. Ithaca. A single spore isolate of B. lactucae was produced and was identified using lettuce differential lines each of which had known gene for resistance. Potted lettuce plants were inoculated with the isolate and incubated at 15 C, at 100% relative humidity for 24 h and then at a relative humidity lower than 70%. Seven days later, the plants were submitted to five different temperatures (5, 10, 15, 20 and 25 C) and six durations of leaf wetness (4, 6, 8, 10, 12 and 14 h). The number of spores produced was determined at the end of each wet period. After 4 h of incubation no spores were observed at any of the temperatures. Highest number of spores was found at 10 and 15 C for more than 10 h of DLW. The rate of sporulation rapidly increased between 8 and 10 h for all the temperatures, including 25 C, where the amount of spores produced was very low. The observed number of spores was transformed into proportion of maximum sporulation (PMS) by providing each data by the maximum number of spores observed for each experiment. The Richards model was used to describe sporulation as a function of leaf wetness duration and the rate and maximum value expressed as a function of temperature. This approach resulted in a three-dimensional equation that explained 87% of the variation in the PMS. Spore viability was also estimated for each temperature and DLW. It was zero after 6 h of incubation and reached almost the maximum after 10 h for all the temperatures. The sporulation model was validated under field conditions and it predicted high, medium, low, or no sporulation in 8 out of 11 times.
5

Matheron, Michael E. "Biology and management of Fusarium wilt of lettuce." College of Agriculture, University of Arizona (Tucson, AZ), 2015. http://hdl.handle.net/10150/575876.

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This publication provides information on the development and management of Fusarium wilt of lettuce. Topics covered include the characteristics of the plant pathogen, disease development, and disease management considerations.
6

Tobar, Tosse Dora Enith [UNESP]. "Linhagens de alface crespa resistentes a Bremia lactucae e interação genótipo x ambiente." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/128168.

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Conseguiu-se avançar progênies F3 de alface-crespa resistentes a B. lactucae, até conseguirem estabilidade fenotípica nas gerações F5 e F6, por meio da seleção tanto dentro como entre famílias, com base na coloração verde-clara e alta crespicidade das folhas, tamanho grande, ausência de brotações laterais, tolerância ao pendoamento precoce e queima dos bordos. Diante do exposto, os objetivos deste trabalho consistiram em caracterizar as linhagens em geração F5: L1, L2, L3 e L4, e em geração F6: L5, L6, L7 e L8, em relação à resistência às raças SPBl:03, SPBl:04, SPBl:05, SPBl:06, SPBl:07, SPBl:09, SPBl:10, SPBl:11 e SPBl:12 de B. lactucae identificadas no Estado de São Paulo e à mistura delas, assim como selecionar linhagens superiores por seus caracteres agronômicos, adaptabilidade e estabilidade, em diferentes municípios e épocas de cultivo por meio da metodologia REML/BLUP, para possibilitar a recomendação das referidas linhagens. Para a caracterização da resistência, o delineamento experimental foi o inteiramente casualizado, em esquema fatorial de 10 X 9, determinado pelas nove raças de B. lactucae e a mistura delas, e pelas oito linhagens de alface-crespa e a cultivar Solaris suscetível, em quatro repetições. Cada raça e a mistura delas foram inoculadas isoladamente e avaliaram-se o índice de latência por meio de notas (notas de 0 a 12), dependendo do dia do aparecimento dos primeiros sinais do patógeno, e a porcentagem de plântulas com esporângios em 20 plântulas por parcela. Para avaliar a adaptabilidade e estabilidade das linhagens, o delineamento experimental utilizado foi de blocos ao acaso, em esquema fatorial 10 x 6 x 2, sendo 10 genótipos (oito linhagens, Vanda e Vera), seis áreas de produtores de alface nos municípios de Monte Alto, São Simão, Aramina, Mogi das Cruzes, Biritiba-Mirim e Salesópolis, e duas épocas de cultivo de Outono-Inverno de 2014 e Primavera- Verão de...
It was possible to advance progenies F3 of crisp leaf lettuce resistant to B. lactucae, to achieve phenotypic stability in the generations F5 and F6, by selecting individuals from both, within and between families, based on the bright green color and high roughness of the leaves, large size, absence of side buds and tolerance to bolting and tip burn. Thus, the aims of this work consisted of characterize the lineages in generations F5: L1, L2, L3, L4, and in generations F6: L5, L6, L7, L8, related to their resistance to the races SPBl:03, SPBl:04, SPBl:05, SPBl:06, SPBl:07, SPBl:09, SPBl:10, SPBl:11 and SPBl:12 of B. lactucae identified in São Paulo State and to their mixture, as well as to select lineages superiors for their agronomic characters, adaptability and stability, in different municipalities and cropping seasons using the REML/BLUP methodology, in order to enable the recommendation of such lineages. To characterize the resistance, the experimental model was completely randomized in a factorial design of 10 X 9, determined by the nine races of B. lactucae and their mixture, and the eight lineages of crisp leaf lettuce and the susceptible cultivar Solaris, with four replications. Each race and their mixture were separately inoculated and the index latency was evaluated by means of notes (notes from 0 to 12) depending on the day of appearance of the first signs of pathogen and the percentage of seedlings with sporangia, in 20 seedlings per plot. To assess lineages adaptability and stability, randomized blocks in a factorial design of 10 x 6 x 2 was used as experimental model, being 10 genotypes (eight lineages, Vanda and Vera), six areas of lettuce producers in the municipalities of Monte Alto, São Simão, Aramina, Mogi das Cruzes, Biritiba-Mirim and Salesópolis, and two cropping periods autumn-winter 2014 and spring-summer 2014-2015, with four replications; it was assessed the volume (cm3/plant), the total and commercial ...
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Tobar, Tosse Dora Enith. "Linhagens de alface crespa resistentes a Bremia lactucae e interação genótipo x ambiente /." Jaboticabal, 2015. http://hdl.handle.net/11449/128168.

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Orientador: Leila Trevisan Braz
Banca: Rita de Cassia Panizzi
Banca: Renata Castoldi
Banca: Rinaldo Cesar de Paula
Banca: Pablo Forlan Vargas
Resumo: Conseguiu-se avançar progênies F3 de alface-crespa resistentes a B. lactucae, até conseguirem estabilidade fenotípica nas gerações F5 e F6, por meio da seleção tanto dentro como entre famílias, com base na coloração verde-clara e alta crespicidade das folhas, tamanho grande, ausência de brotações laterais, tolerância ao pendoamento precoce e queima dos bordos. Diante do exposto, os objetivos deste trabalho consistiram em caracterizar as linhagens em geração F5: L1, L2, L3 e L4, e em geração F6: L5, L6, L7 e L8, em relação à resistência às raças SPBl:03, SPBl:04, SPBl:05, SPBl:06, SPBl:07, SPBl:09, SPBl:10, SPBl:11 e SPBl:12 de B. lactucae identificadas no Estado de São Paulo e à mistura delas, assim como selecionar linhagens superiores por seus caracteres agronômicos, adaptabilidade e estabilidade, em diferentes municípios e épocas de cultivo por meio da metodologia REML/BLUP, para possibilitar a recomendação das referidas linhagens. Para a caracterização da resistência, o delineamento experimental foi o inteiramente casualizado, em esquema fatorial de 10 X 9, determinado pelas nove raças de B. lactucae e a mistura delas, e pelas oito linhagens de alface-crespa e a cultivar Solaris suscetível, em quatro repetições. Cada raça e a mistura delas foram inoculadas isoladamente e avaliaram-se o índice de latência por meio de notas (notas de 0 a 12), dependendo do dia do aparecimento dos primeiros sinais do patógeno, e a porcentagem de plântulas com esporângios em 20 plântulas por parcela. Para avaliar a adaptabilidade e estabilidade das linhagens, o delineamento experimental utilizado foi de blocos ao acaso, em esquema fatorial 10 x 6 x 2, sendo 10 genótipos (oito linhagens, Vanda e Vera), seis áreas de produtores de alface nos municípios de Monte Alto, São Simão, Aramina, Mogi das Cruzes, Biritiba-Mirim e Salesópolis, e duas épocas de cultivo de Outono-Inverno de 2014 e Primavera- Verão de...
Abstract: It was possible to advance progenies F3 of crisp leaf lettuce resistant to B. lactucae, to achieve phenotypic stability in the generations F5 and F6, by selecting individuals from both, within and between families, based on the bright green color and high roughness of the leaves, large size, absence of side buds and tolerance to bolting and tip burn. Thus, the aims of this work consisted of characterize the lineages in generations F5: L1, L2, L3, L4, and in generations F6: L5, L6, L7, L8, related to their resistance to the races SPBl:03, SPBl:04, SPBl:05, SPBl:06, SPBl:07, SPBl:09, SPBl:10, SPBl:11 and SPBl:12 of B. lactucae identified in São Paulo State and to their mixture, as well as to select lineages superiors for their agronomic characters, adaptability and stability, in different municipalities and cropping seasons using the REML/BLUP methodology, in order to enable the recommendation of such lineages. To characterize the resistance, the experimental model was completely randomized in a factorial design of 10 X 9, determined by the nine races of B. lactucae and their mixture, and the eight lineages of crisp leaf lettuce and the susceptible cultivar Solaris, with four replications. Each race and their mixture were separately inoculated and the index latency was evaluated by means of notes (notes from 0 to 12) depending on the day of appearance of the first signs of pathogen and the percentage of seedlings with sporangia, in 20 seedlings per plot. To assess lineages adaptability and stability, randomized blocks in a factorial design of 10 x 6 x 2 was used as experimental model, being 10 genotypes (eight lineages, Vanda and Vera), six areas of lettuce producers in the municipalities of Monte Alto, São Simão, Aramina, Mogi das Cruzes, Biritiba-Mirim and Salesópolis, and two cropping periods autumn-winter 2014 and spring-summer 2014-2015, with four replications; it was assessed the volume (cm3/plant), the total and commercial ...
Doutor
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Kim, Seung-Chul. "Origin and evolution of woody Sonchus and five closely related genera (Asteraceae: Lactuceae) in Macaronesia /." The Ohio State University, 1997. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487946776021135.

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Goodenough, Lynn. "Investigations into the mode of action of dimethomorph in Phytophthora species and Bremia lactucae." Thesis, University of Exeter, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337763.

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Mesquita, Paulo Goes. "Biologia, epidemiologia e controle do míldio (Bremia lactucae) da alface (Lactuca sativa) em viveiro." reponame:Repositório Institucional da UnB, 2008. http://repositorio.unb.br/handle/10482/5572.

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Dissertação (mestrado)—Universidade de Brasília, Instituto de Ciências Biológicas, Departamento de Fitopatologia, 2008.
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Sintomas e sinais do míldio foram observados e coletados em plantas de alface (Lactuca sativa) no Distrito Federal. Foi observado o estágio assexual do patógeno (Bremia lactucae). Descrições detalhadas, com observações morfológicas e medidas morfométricas de microscopia óptica do estágio assexual foram realizadas. A patogenicidade do míldio proveniente do Núcleo Rural da Vargem Bonita e seu período de latência, em quatro diferentes estádios de desenvolvimento de cultivares comerciais de alface foram estudados por inoculação artificial em ensaios realizados na Estação Biológica da Universidade de Brasília. Quando observado o “ranking” de suscetibilidade das cultivares nos quatro diferentes estádios de desenvolvimento para o período de latência, observou-se diferentes níveis de resistência entre as cultivares. Além disso, observou-se que a resistência parece aumentar com o desenvolvimento fenológico do hospedeiro. O “ranking” relativo das cultivares não foi afetadopelo estádio de desenvolvimento. _________________________________________________________________________________ ABSTRACT
Symptoms and signs of downy mildew were observed and collected in lettuce plants (Lactuca sativa) in Distrito Federal, Brazil. Only the asexual stage of the pathogen (Bremia lactucae) was observed. Detailed descriptions, including fungal morphology and morphometrics were performed with light microscopy. The pathogenicity of downy mildew, collected in Núcleo Rural da Vargem Bonita, as well as it latent period in four phenological stages of lettuce commercial cultivars were studied by artificial inoculation in experiments conducted at Biological Station of University of Brasilia - UnB. Latent period was useful to separate cultivars by resistance level. In addition, results indicated that genetic resistance to downy mildew in lettuce seems to increase with plant development. The relative ranking of susceptibility among cultivars remained constant in all four phenological stages.
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Книги з теми "Lactucine":

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Kilian, Norbert. Revision of Launaea Cass. (Compositae, Lactuceae, Sonchinae). Berlin: Botanischen Garten und Botanischen Museum Berlin-Dahlem, 1997.

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Частини книг з теми "Lactucine":

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Schweingruber, Fritz Hans, Miroslav Dvorský, Annett Börner, and Jiří Doležal. "Asteraceae – Lactuceae." In Atlas of Stem Anatomy of Arctic and Alpine Plants Around the Globe, 15–20. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-53976-4_3.

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Bohm, Bruce A., and Tod F. Stuessy. "Flavonoids of Lactuceae." In Flavonoids of the Sunflower Family (Asteraceae), 328–39. Vienna: Springer Vienna, 2001. http://dx.doi.org/10.1007/978-3-7091-6181-4_13.

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van Pelt-Heerschap, Hilde, and Olga Smit-Bakker. "Cell-Wall Degrading Enzymes Synthesized by the Obligate Pathogen Bremia Lactucae." In Developments in Plant Pathology, 82. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-1737-1_18.

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4

Rubin, Avia E., Ayelet-Chen Werdiger, Mathias Blum, Ulrich Gisi, Helge Sierotzki, Dietrich Hermann, and Yigal Cohen. "EMS and UV irradiation induce instable resistance against CAA fungicides in Bremia lactucae." In The Downy Mildews - Biology, Mechanisms of Resistance and Population Ecology, 207–19. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-94-007-1281-2_15.

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5

Reinink, K., R. Groenwold, and A. Lebeda. "Characterization of Non Host Resistance to Lettuce Downy Mildew (Bremia lactucae) in Lactuca Saligna." In Durability of Disease Resistance, 340. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2004-3_67.

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Mansfield, J. W., A. M. Woods, J. Fagg, and M. Bennett. "Control of the Hypersensitive Reaction of Lettuce to the Downy Mildew Fungus Bremia Lactucae." In NATO ASI Series, 251–60. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74158-6_30.

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Street, P. F. S., P. M. Rowell, D. N. Crucefix, F. Didehvar, and J. W. Mansfield. "Race Specific Resistance to Bremia Lactucae is Expressed by Lettuce Cells in Suspension Culture." In Recognition in Microbe-Plant Symbiotic and Pathogenic Interactions, 243–51. Berlin, Heidelberg: Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-71652-2_23.

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Woiwod, Ian P., Peter Rothery, and Xilong Zhou. "Analysis of Population Fluctuations in the Aphid Hyperomyzus Lactucae and the Moth Perizoma Alchemillata." In Chaos in Real Data, 97–120. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-011-4010-2_5.

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Petrželová, Irena, and Aleš Lebeda. "Distribution of race-specific resistance against Bremia lactucae in natural populations of Lactuca serriola." In The Downy Mildews - Biology, Mechanisms of Resistance and Population Ecology, 101–21. Dordrecht: Springer Netherlands, 2010. http://dx.doi.org/10.1007/978-94-007-1281-2_8.

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Petrželová, I., and A. Lebeda. "Temporal and Spatial Variation in Virulence of Natural Populations of Bremia Lactucae Occurring on Lactuca Serriola." In Advances in Downy Mildew Research — Volume 2, 141–63. Dordrecht: Springer Netherlands, 2004. http://dx.doi.org/10.1007/978-1-4020-2658-4_9.

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Тези доповідей конференцій з теми "Lactucine":

1

Raynal-Lacroix, Christiane. "Relation between phosphorus fertilisation and protection of lettuce against Bremia lactucae." In VII South-Eastern Europe Syposium on Vegetables & Potatoes. University of Maribor Press, 2017. http://dx.doi.org/10.18690/978-961-286-045-5.72.

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