Дисертації з теми "Laboratory Risks"
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Aurangabadwala, Tehsin T. "DEVELOPMENT OF AN EXPERT ALGORITHM TO IDENTIFY RISKS ASSOCIATED WITH A RESEARCH FACILITY." Ohio University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1173823780.
Повний текст джерелаHamad, Maitham. "Determination of Shrinkage Crack Risks in Industrial Concrete Floors through Analyzing Material tests." Thesis, KTH, Bro- och stålbyggnad, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-103081.
Повний текст джерелаPoteet, Thomas L. "Benefits, costs and risks of converting from military design specifications to commercial performance standards at a commercial laboratory." Thesis, Monterey, Calif. : Springfield, Va. : Naval Postgraduate School ; Available from National Technical Information Service, 1999. http://handle.dtic.mil/100.2/ADA366172.
Повний текст джерела"June 1999". Thesis advisor(s): Walter E. Owen, Mark E. Nissen. Includes bibliographical references (p. 151-155). Also available online.
Rozmankova, Eliška. "Currently used pesticides and their mixtures : what are the risks to non-target aquatic organisms? Laboratory and in situ approaches." Thesis, Bordeaux, 2020. http://www.theses.fr/2020BORD0301.
Повний текст джерелаPesticides have enabled humankind to protect its crops from pests, intensifying thus the crop yields to sustain the growing population. However, pesticides often end up in aquatic water bodies, e.g. via field runoff, where they may harm non-target organisms. The environmental concentrations of pesticides are often considered safe for aquatic ecosystems although they might induce sublethal changes in exposed organisms. Moreover, the organisms are generally not dealing with only one pesticide issued from a nearby field but with a complex mixture of various chemical compounds, interacting amongst themselves, and creating a toxic cocktail with unknown and hardly predictable impacts. These compounds, each with different environmental fate, eventually degrade and form more or less toxic and persistent metabolites aggravating the complexity of the mixtures.This dissertation thesis summarizes the state-of-the-art in pesticide mixture toxicity research and is composed of five research articles dealing with sublethal effects of selected pesticides on non-target aquatic species. Vulnerable embryo-larval stages of two model organisms: freshwater zebrafish (Danio rerio) and euryhaline bivalve Pacific oyster (Magallana gigas) were used to assess the sublethal toxicity of especially environmental concentrations (detected in selected European water bodies) of commonly used herbicide S metolachlor with its two metabolites metolachlor oxanilic acid and metolachlor ethanesulfonic acid, insecticide imidacloprid, and fungicide propiconazole, alone and in a mixture. A complementary in situ approach was carried out to evaluate a real impact on early-life stages of the Pacific oyster in Arcachon Bay in France, a final recipient of various substances including pesticides from respective watersheds.First, zebrafish embryo-larval stages were observed to be highly sensitive to environmentally relevant concentrations of propiconazole and to a lesser extent also to imidacloprid. In contrast, S-metolachlor and its metabolites had almost no effect on their development, neurobehavioral functions, or gene expression except for altered genes implicated in the thyroid system. A mixture of these compounds exhibited a concentration addition effect on zebrafish development. These observations imply that the development of freshwater fish may be at risk with current agricultural practice.Second, a study with Pacific oyster embryos and larvae revealed very low toxicity of propiconazole and imidacloprid on their development and locomotion patterns. Few effects caused by these compounds were observed at the molecular level, as well as the effects caused by the mixture. The environmental concentration of the mixture induced developmental malformations in oyster larvae, however, those exposed in situ in Arcachon Bay did not show higher proportions of abnormal larvae suggesting that the water quality of Arcachon Bay is sufficient for oyster development. Nevertheless, oyster larvae exposed in the inner part of Arcachon Bay showed different gene expression levels than larvae from the reference site located near the ocean entrance, which may indicate consequences of a potential long term impact.These results documented that embryo-larval stages of zebrafish and Pacific oysters are relevant tools for the assessment of low concentrations of pesticides and pesticides in a mixture, and that laboratory studies complemented with field research are useful for (eco)toxicity assessment and of high ecological relevance
Burmann, Laura Sanz. "Sistemática para avaliar as condições de segurança e saúde em laboratório de ensaios de materiais elétricos." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2008. http://hdl.handle.net/10183/13883.
Повний текст джерелаThe conditions of work in laboratories of test of materials and equipment, used in nets of electric energy, expose the workers to serious risks of accident. However, there are few studies about this matter with ergonomic approach. Thus, the purpose of this study was to elaborate a systematics to evaluate these conditions, being aimed to reduce the risks of occupational accidents and illnesses in these laboratories. The approach of this work was applied in four stages: the first one corresponded to the analysis of the demand, with the survey of security and health indexes; the second stage was based on the construction and application of a tool of analysis of the general conditions of security the existing Brazilian norms; the third stage was given by the construction and application of a tool to identificate the risks of the activities; the fourth and last stage used the application of the Deparis Method to diagnosis risks in the activities, from the perception of the worker. As result, the systematics revealed efficient, evidencing situations that must cause damages to the health and the physical integrity of the workers of the analyzed laboratory. The approach seemed to be simple to understand and to be applied and allowed the confrontation of distinct sides (analyst and operators), evidencing with most precision the analyzed risks.
Brinkman, Jacoline Willijanne. "Albuminuria as a laboratory risk marker methods evaluated /." [S.l. : Groningen : s.n. ; University Library Groningen] [Host], 2007. http://irs.ub.rug.nl/ppn/304605956.
Повний текст джерелаSen, Shabori. "BEHAVIORAL RESPONSE TO ENDOGENOUS RISK IN THE LABORATORY." Doctoral diss., University of Central Florida, 2010. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2658.
Повний текст джерелаPh.D.
Department of Economics
Business Administration
Economics PhD
Marshall, Rafael. "An investigation of risk homeostasis in a laboratory environment." Thesis, Virginia Tech, 1991. http://hdl.handle.net/10919/41685.
Повний текст джерелаMaster of Science
Suchý, Ivo. "Možnosti managementu rizik zkušebních laboratoří v kontextu revidovaných norem systémů managementu." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2018. http://www.nusl.cz/ntk/nusl-382730.
Повний текст джерелаPaton, Wendy Jane. "Risk factors for laboratory-induced and self-reported false confessions." Thesis, Glasgow Caledonian University, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.700986.
Повний текст джерелаVorster, Nina. "Investigating the views and expectations of pregnant women who undergo genetic counselling for age-related risk of aneuploidy." Master's thesis, Faculty of Health Sciences, 2020. http://hdl.handle.net/11427/33968.
Повний текст джерелаGioia, Francesca. "Determinants of risk behaviour : three laboratory experiments on peer effects, group identity and incentive schemes." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31071.
Повний текст джерелаSchluep, Mathias. "Dissolution, biodegradation and risk in a diesel fuel contaminated aquifer - modeling and laboratory studies /." [S.l.] : [s.n.], 2000. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=13713.
Повний текст джерелаÖdborn, Jönsson Linnéa. "Mapping re-growth following chemotherapy in high-risk neuroblastoma : The research process in laboratory work." Thesis, KTH, Lärande, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-253038.
Повний текст джерелаSyftet med studien är att studera hög-risk cancerceller inom barncancersjukdomen neuroblastom (NB), genom att kartlägga återväxt efter kemoterapi-behandling med doxorubicin (doxo). En multiresistent neuroblastom cell-linje med hög-risk egenskaper, SK-N-BE(2)-C( BE[2]-C), användes som modell. Enligt en tidigare studie på BE(2)-C celler, utförd av Hultman et al., (2018), kan efter en enkel eller dubbelbehandling med doxo majoriteten av cellerna överleva, men endast en mycket liten andel kan också omedelbart fortsätta dela sig. Dessa celler benämndes som ”kvarvarande replikerande celler” (RRC). I denna studie undersöktes hypotesen att RRC är ansvariga för återväxt efter doxo-terapi, hypotetiskt återspeglande situationen vid återfall hos patienten. BE(2)-C celler odlades in vitro i petriskålar, behandlades med doxo, och analyserades sedan i mikroskop genom att använda två kemiska markörer för cell-delning; EdU (5-etynyl-2’-deoxyuridin) och BrdU (5-bromo-2-deoxyuridin). Intressant nog, men något oväntat, indikerar resultaten att RRC troligen inte är ansvariga för återväxt. Detta skulle då tyda på att återväxten orsakas av andra cellpopulationer, utan förmåga att omedelbart efter kemoterapin fortsätta dela sig. Dock förekom tekniska utmaningar med valda metoder, t.ex. gränsvärdena för EdU- och BrdU-detektering, i kombination med utspädningen av DNA-markörer vid replikation. Därför krävs ytterligare studier med användning av andra metoder, t.ex. isotopmarkörer, för att fastställa vilka subpopulationer som är ansvariga för återväxt. Utöver att studera cellpopulationer ansvariga för återväxt så genomfördes även en pilotstudie med en kombination av doxo och annan typ av kemoterapi riktad mot cellens förmåga att reparera DNA skador; en ATM-inhibitor (KU-60019). Pilotstudien indikerar att återväxten av BE(2)-C förskjuts vid närvaro av KU-60019, både i kombination med enkel eller dubbelbehandling av kemoterapin doxo. Det naturvetenskapliga arbetssättet i denna studie, vilket inkluderas i ämnesplanerna för de naturvetenskapliga ämnena för gymnasieskolan, understryker betydelsen av att studera laborativt arbete. En litteraturstudie genomfördes med fokus på öppna och slutna laborationer. Tio forskningsartiklar analyserades och karaktäriserades; typ av laborationsstil (öppen eller sluten) och elevers lärandekompetenser. Resultatet från denna studie indikerar att öppna laborationer bidrar till att öka elevers intresse. Vidare visar resultatet att laborativt arbete i skolan inkluderar utvecklingen av främst problemlösningsförmågan och procedurförmågan. Forskningsprocedurer och processer involverade i detta examensarbete diskuteras.
Augustsson, Hanna. "Ethoexperimental studies of behaviour in wild and laboratory mice : risk assessment, emotional reactivity and animal welfare /." Uppsala : Dept. of Large Animal Clinical Sciences, Swedish Univ. of Agricultural Sciences, 2004. http://epsilon.slu.se/v174.pdf.
Повний текст джерелаJohnson, James G. "The facilitative factor of an undergraduate wellness laboratory course on affecting wellness attitudes and behavior /." free to MU campus, to others for purchase, 2001. http://wwwlib.umi.com/cr/mo/fullcit?p3025626.
Повний текст джерелаŠindler, Martin. "Laboratorní úloha útoků na protokol HTTPS." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2017. http://www.nusl.cz/ntk/nusl-316694.
Повний текст джерелаEstcourt, Lise Jane. "Risk factors for haemorrhage in patients with haematological malignancies." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:4efbd9b1-62e5-4536-a5ee-df5eea4620d0.
Повний текст джерелаZavislak, Naomi M. "The influence of similarity on perceptions of risk for negative outcomes : two laboratory experiments and a field investigation of breast cancer survivors /." Thesis, Connect to this title online; UW restricted, 2004. http://hdl.handle.net/1773/8999.
Повний текст джерелаJames, Jonathan Peter. "Field and laboratory analyses of manual tasks in the South African automotive industry." Thesis, Rhodes University, 2007. http://hdl.handle.net/10962/d1005199.
Повний текст джерелаZavřel, Patrik. "Audit BOZP v těžké laboratoři C1." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2019. http://www.nusl.cz/ntk/nusl-402551.
Повний текст джерелаVirágová, Tereza. "Management rizik v prostředí zkušební laboratoře." Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2016. http://www.nusl.cz/ntk/nusl-241282.
Повний текст джерелаStenlund, Tobias. "Seated postural reactions to mechanical shocks : laboratory studies with relevance for risk assessment and prevention of musculoskeletal disorders among drivers." Doctoral thesis, Umeå universitet, Fysioterapi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-117178.
Повний текст джерелаFischer, Shira H. "Factors Associated with Ordering and Completion of Laboratory Monitoring Tests for High-Risk Medications in the Ambulatory Setting: A Dissertation." eScholarship@UMMS, 2011. https://escholarship.umassmed.edu/gsbs_diss/543.
Повний текст джерелаGarcia, Thomas. "A behavioral approach of decision making under risk and uncertainty." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE2042/document.
Повний текст джерелаThis thesis investigates how individuals make decisions under risk and uncertainty. It is composed of four essays that theoretically and experimentally investigate decision-making.The first two essays study situations where a decision maker has to decide whether an event has occurred using uncertain evidence. Accurately identifying that this event has occurred is more rewarded than accurately identifying that it has not occurred. This decision problem induces a divergence between two qualities of a decision: optimality and accuracy. Both essays reproduce such situations in a laboratory experiment based on perceptual tasks and analyze behavior using Signal Detection Theory to study the optimality-accuracy trade-off. The first essay confirms the existence of the trade-off with a leading role of accuracy. It explains the trade-off by the concern of individuals for being right. The second chapter finds that presenting perceptual evidence last contributes to the existence of the optimality-accuracy trade-off.The third essay studies how other-regarding preferences interact with attitude toward ambiguity. It reports the results of an experiment where subjects have to make donations to charities. Donations may have either ambiguous costs or ambiguous benefits. We find that other-regarding preferences are decreased under ambiguity. In other terms, we highlight that individual use ambiguity has an excuse not to give. This excuse-driven behavior is stronger for ambiguous costs than ambiguous benefits.The fourth essay challenges the external validity of laboratory risk preference measures using behavior in experimental risk tasks and naturally occurring behavior under risk. We find that risk preference measures are related with the former but that they fail to explain the latter
Garcia, Thomas. "A behavioral approach of decision making under risk and uncertainty." Thesis, Queensland University of Technology, 2019. https://eprints.qut.edu.au/132313/1/Thomas%20Jean-Christophe%20Lucien_Garcia_Thesis.pdf.
Повний текст джерелаSutinen, Jessica. "Identifying Comorbid Risk Factors of West Nile Neuroinvasive Disease in the Ontario Population, 2002-2012, Using Laboratory and Health Administrative Data." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40644.
Повний текст джерелаKeefer, Chelsea Elizabeth. "Use of Plant Growth Regulators to Expand the Period of Sagebrush Seed Germination and Reduce the Risk of Restoration Failure: Laboratory Trials." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/8576.
Повний текст джерелаTrujillo, Michael A. "A LABORATORY STUDY OF STRESS REACTIONS TO WITNESSING A POLICE KILLING OF AN UNARMED BLACK MAN: DISCRIMINATION, DISTRESS TOLERANCE, ETHNIC IDENTITY, AND RISK-TAKING." VCU Scholars Compass, 2018. https://scholarscompass.vcu.edu/etd/5370.
Повний текст джерелаSalie, Faatiema. "An investigation into turbine ventilators as a potential environmental control measure to minimise the risk of transmission of tuberculosis - a laboratory and field study." Master's thesis, University of Cape Town, 2014. http://hdl.handle.net/11427/13285.
Повний текст джерелаTB is an airborne infectious disease which is spread by droplet nuclei, carrying Mycobacterium tuberculosis, in the air. The droplet nuclei small enough to enter human respiratory pathways are 1-5 μm in size and are able to travel long distances (Hodgson, et al., 2009) (WHO, 1999), and can be distributed widely throughout (hospital) buildings (Beggs, Noakes, Sleigh, Fletcher, & Siddiqi, 2003). These droplet nuclei may remain suspended in the air until they are removed by dilution ventilation or other disinfection methods (Parsons, Hussey, Abbott, & de Jager, 2008) (National Department of Health, 2007). Dilution ventilation refers to the dilution of contaminated air with “clean” air (ACGIH, 2005), thereby reducing the concentration of contaminants in the room. One of the recognised approaches for minimising the risk of transmission of TB is to adequately ventilate the contaminated room/space. A higher ventilation rate can provide higher dilution capability, in turn reducing the risk of airborne infections (WHO, 2009). The parameters of concern in ventilation design are ventilation flow rate and airflow pattern in the room (and building). The former reduces contaminant concentration while the latter aims to move uncontaminated air to high risk areas, and contaminated air away from occupied areas, usually to the outside. The shortcomings of conventional natural ventilation strategies are well documented. The aim of this research project is to review and study the effectiveness of natural ventilation design supplemented by a turbine ventilator. The project was divided into two components: a field study and laboratory experiments. In the field study, a turbine ventilator was installed into a bedroom of a low-income house in Pretoria. Tracer gas (concentration decay) tests were performed to determine the ventilation flow rates, mean age of air and air change efficiency of four natural ventilation configurations. These included infiltration/leakage (IL), two cases of single-sided ventilation (SS1 and SS2), and crossventilation (CV). Three baseline (without the turbine ventilator) and three turbine ventilator tests were performed, one each in the morning, noon and afternoon. The tests were performed between February and April 2011 on typical summer days. The turbine ventilator was then tested in a laboratory environment under wind, buoyancy and a combination of wind and buoyancy forces. The wind speeds were low, ranging from 0.0 to 0.5 m/s (0.0 to 1.8 km/h), and the temperature differential tested was in the range of 5.5 to 9.3˚C. The in-duct velocities and centreline velocities were investigated to establish if, under the subjected force(s), a capture envelope described by Dalla Valle’s equation could be measured. This envelope would be used to determine if the turbine ventilator could potentially reduce the concentration of airborne contaminants in the test volume. In the field study baseline tests, IL, SS1, CV and SS2 mean – and range of - ventilation flow rates of 0.6 [0.5 – 0.6], 8.1 [6.8 – 9.3], 16.9 [14.7 – 19.0] and 7.4 [7.0 – 7.9] ACH, respectively, were reported. The baseline tests highlight the potential of cross-ventilation where, by simply opening windows and doors, a ventilation rate exceeding IPC recommendations was obtained. All configurations, save An investigation into turbine venti lators as a potential environmental co ntrol measur e to minimise the risk of transmission on TB Page IV SS1, appear to have approached the fully-mixed case.SS1 also showed the greatest variability in ventilation flow rates. This finding is not unexpected, as air exchange in single-sided ventilation is due to wind pressure fluctuations, which varied across each test. In addition, in all tests it was found that the ventilation flow rate was dependant on the natural ventilation configuration and openable area, and not necessarily environmental conditions. In the turbine ventilator tests, the mean ventilation flow rates for IL, SS1, CV and SS2 were 1.8 [1.6 – 2.1], 5.4 [5.2 – 5.7], 17.7 [16.0 – 18.6] and 9.5 [8.5 – 10.1] ACH, respectively. The mean ventilation flow rate increased in IL and SS2 with the installation of the turbine ventilator, while in SS1 a decrease was reported. The increase in ventilation flow rate in IL was found to be due to natural convection, where the turbine ventilator merely facilitated the exhaustion of warm air. The results of the field study are specific to the environmental conditions at the time of the test, and are not generalizable. In the laboratory experiments, the in-duct velocity increased with an increase in wind speed and temperature differential. For a given temperature differential, an increase in wind speed resulted in a decrease in in-duct velocity. Across all tests, no centreline velocity profile, described by the Dalla Valle equation, could be measured. In the wind speed tests, no capture envelope could be established. This was due to the low wind speed test range, where the resulting centreline velocity was beyond the limit of detection of the thin-film sensors. In the buoyancy forces test, a turbulent region near the base of the turbine ventilator was realised, where the magnitude and direction of the air flowing at 1.5D continuously changed. This turbulent region was again observed in the combined wind and buoyancy forces tests, though the magnitude was smaller and occurrence less frequent. The results of the laboratory experiments are specific to the parameters tested, and are not generalizable. By correlating the field study, laboratory experiments, and previous (similar) studies, it was concluded, that, under the tested conditions, adding a turbine ventilator as a supplement to natural ventilation system will not reduce the concentration of contaminants in the occupied zone in a room.
Marini, Matteo Maria. "Essays in Behavioural and Experimental Economics: Emotions, Uncertainty and Cooperation." Doctoral thesis, Universitat Jaume I, 2019. http://hdl.handle.net/10803/666278.
Повний текст джерелаEn el primer capítulo de la tesis se realiza un experimento de laboratorio con el fin de estudiar el efecto de las emociones de tristeza y felicidad, sentidas como casuales no relacionadas con la decisión propiamente dicha, sobre la toma de decisiones bajo riesgo. El análisis revela que los dos tipos de emociones, tanto tristeza como felicidad, suponen mayor aversión al riesgo en relación a condiciones neutrales, un resultado que puede moderarse por la tarea de elicitación de actitud frente al riesgo. El segundo capítulo es un metanálisis de estudios experimentales sobre el tema analizado en el primer capítulo, con el objetivo de explicar la heterogenidad tradicional de los resultados en la literatura sobre el tema. Como resultado, las emociones inducen mayor nivel de aversión al riesgo cuando la elicitación se realiza a partir de una lista múltiple de precios à la Holt and Laury (2002) en vez de con métodos de preferencias declaradas. También ocurre cuando la tarea de elicitación de la actitud frente al riesgo se etiqueta como una decisión de inversión en vez de una elección abstracta. El tercer capítulo ofrece evidencia sobre el impacto de la comunicación en la provisión de bienes públicos cuya calidad es incierta. Se encuentra que la comunicación incrementa de forma significativa la provisión del bien público reduciendo la ineficiencia que proviene de una contribución derrochadora e ineficiente, sin embargo se observa una masiva sobre-contribución. Por lo tanto, se propone la búsqueda de pagos simétricos dentro del grupo como explicación persuasiva y se especula en definitiva que, en condiciones de incertidumbre, se prioriza satisfacer a optimizar.
Bertling, Sofia. "Corrosion-included metal runoff from external constructions and its environmental interaction : a combined field and laboratory investigation of Zn, Cu, Cr and Ni for risk assessment." Doctoral thesis, KTH, Materialvetenskap, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-175.
Повний текст джерелаQC 20100901
Bertling, Sofia. "Corrosion-induced metal runoff from external constructions and its environmental interaction : a combined field and laboratory investigation of Zn, Cu, Cr and Ni for risk assessment /." Stockholm, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-175.
Повний текст джерелаLampach, Nicolas. "Essays on risk management in the presence of ambiguity." Thesis, Strasbourg, 2016. http://www.theses.fr/2016STRAB009/document.
Повний текст джерелаThe thesis aims to establish an optimal technological risk management to ensure hazard reduction of new emerging risks without impeding the innovation path. The research work contributes to ex-ante and ex-post risk management strategies and provides theoretical and empirical evidence to address the management of new emerging risks. The first part of the thesis examines, from the perspective of Law and Economics, the effectiveness of the tort liability rule for the situation where the decision maker is lacking information about the probability of an event to occur. The second part of the thesis pays particular attention to the environmental energy transition in France and focus on the insurability of the energy performance in the housing sector. The theoretical and experimental findings from the first part of the research convey strong validity that tort law cannot provide ex-ante optimal incentives when there is lacking information about the probability of accident. The regime of unlimited and limited liability leads to overinvestment in prevention in regard to new emerging risks. The empirical results of the second part of the thesis reveal that 23.75% of households participated in the weatherization program "Je Rénove BBC" do not achieve the required energy target but the severity of the energy performance gap is relatively low. The findings of the research work imply several policy recommendations to manage new emerging technologies in the future
Soler, Lecha Anna. "Desenvolupament de la gestió del risc al laboratori clínic. Aplicació al procés analític del Programa de Cribratge Neonatal de Catalunya." Doctoral thesis, Universitat de Barcelona, 2020. http://hdl.handle.net/10803/670019.
Повний текст джерелаRisk management has been introduced in clinical laboratories in recent years. Failure Modes and Effects Analysis (FMEA) and Sigma metrics have been used for the risk management of the analytical process of the Neonatal Screening Program of Catalonia from 2016 to 2018. The methodological sequence that has been used was: firstly, the application of FMEA and Sigma metrics; secondly, the establishment of a correspondence of the degree of agreement of the information provided by the two methodologies, and finally, the criteria to decide whether or not to accept the risk have been defined The results of the study show that 48 risks have been detected throughout the analytical process of the Neonatal Screening Program: 14 in the pre-pre-analytical phase, 6 in the pre-analytical phase, 22 in the analytical phase, 5 in the post-analytical phase and 1 in the post-post-analytical phase. It was found that in 14 risks there was no agreement between the results of the NPR provided by the FMEA and the Sigma value. Another 28 were considered marginal risks and improvement actions were not required. A further 6 risks were classified as not acceptable risks and required the introduction of improvement actions and were distributed as follows: 4 in the pre-analytical phase; 1 in the analytical phase and 1 in the post-analytical phase. It has been the laboratory or the Public Health Agency of Catalonia (in agreement with laboratory staff), who established the improvement actions with the aim of mitigating or eliminating the risks. In order to demonstrate that the developed methodology may be applicable in other areas of the clinical laboratory, results of its application to the extra-analytical phases of the analytical processes carried out at the Biomedical Diagnostic Centre are also shown. These results show that the proposed methodology can be useful for the risk management of any activity undertaken in a clinical laboratory. Moreover, FMEA and Sigma metric tools give complementary information in addition to risk prioritization. FMEA highlights the severity and ability to detect a potential error, while Sigma metrics provide an idea of process performance.
Öberg, Mattias U. L. "Health risk assessment of dioxin-like compounds in complex samples /." Stockholm : Karolinska inst, 2003. http://diss.kib.ki.se/2003/91-7349-692-8.
Повний текст джерелаAttallah, May. "Strategies of Information Acquisition Under Uncertainty." Thesis, Rennes 1, 2017. http://www.theses.fr/2017REN1G023/document.
Повний текст джерелаThe objective of this thesis is to present four essays in behavioral and experimental economics on decision-making under risk and ambiguity. The first essay presents a synthesis and a point of view on the representativeness of experimental results regarding individual preferences: social preferences and risk and time preferences, in developed countries as well as in developing countries. The second essay explores experimentally the effect of risk and ambiguity on job search behavior in an infinite horizon. The results show that in risk and ambiguity, reservation wages are lower than the theoretical values and decrease during the search process. Similarly, subjects behave as ambiguity neutral agents. The third and fourth essay examine the effect of the social context and the correlation of payments on attitudes towards risk and ambiguity respectively in gain, loss and mixed domain. The results show that the introduction of the social context has a significant effect on attitudes towards risk in all three domains. Nevertheless, the correlation of risks has an effect on risk attitudes only in the mixed domain. As for ambiguity, ambiguity attitudes vary across domains. The correlation of payments decreases ambiguity aversion
Rosa, Diego Antonio de Oliveira. "Gerenciamento de risco aplicado a procedimentos de ensaios de equipamentos eletromédicos." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/3/3142/tde-12062013-165607/.
Повний текст джерелаTo better evaluate the medical electrical equipment the laboratories for testing will need to deploy in its management system, the process of Risk Management. This new theme is prescribed in the edition of ABNT NBR IEC 60601-1:2010, which will take effect from 2012 in Brazil. This research aims to show brief the process used to implement the Risk Management procedures for testing medical electrical equipment, to meet the new requirements of the series of ABNT NBR IEC 60601/80601 aiming at continuous improvement of the management systems of laboratories for testing accredited by INMETRO. The method used for the development of this research was the detailed study of two Brazilian editions of the General Standard, Collateral Standards, Particular Standard of infusion pumps and controllers, as well as the ABNT NBR ISO 14971:2009. After studying these Standards, some Risk Management files provided by manufacturers of medical electrical equipment were analyzed and performed the study of some tools used for the development of Risk Management, for example, FMEA, FTA and HAZOP. Trainings were also conducted to the whole laboratory for testing team. With these activities, it was possible to develop and deploy the necessary testing procedures in DEC-LEB/EPUSP and validate procedures for testing. An infusion pump for the validation of these procedures was used, along with all its accompanying documents. The final result was the training of DEC-LEB/EPUSP team for testing as new editions of the standards that incorporate Risk Management in their prescriptions, concluding that laboratories for testing must include appropriate procedures and training of their human resources.
Gontijo, Érica Eugênio Lourenço. "Comparação do sucesso na produção e qualidade de embriões entre um laboratório convencional e um laboratório ISO 5/7 e fatores relacionados a gravidez." Universidade Federal de Goiás, 2016. http://repositorio.bc.ufg.br/tede/handle/tede/6217.
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Outro
INTRODUCTION: The frequency of embryo production and successful pregnancy are the main parameters used to measure the quality of human reproduction laboratories. OBJECTIVE: We compared the success in the production and quality of embryos, success rate and factors related to pregnancy in LabRep/HC/UFG before deep adjustments estrututurais, when it was classified as conventional laboratory and after adequaçãos, when it began to be classified as an ISO 5/7 laboratory and factors related to the success of fertilization. METHOD: The study was divided into two parts. The first evaluated the embryo quality and the second risk factors capable of interfering with the success of pregnancy. information of 278 cycles of women were surveyed who submitted any Assisted Human Reproduction technique during the study period. In the first analysis were surveyed: cleavage of the embryo, the result of βHCG, embryo quality and microbiological contamination of the means of embryos crops. In the second, they evaluated the size of follicles per woman, amount of aspirated oocytes, raised, inseminated and injected, ovarian stimulation scheme, maternal infections, infertility period and sperm quality. The study design was a case control. Data were entered into Epi-Info 3.3.2 and analyzed in BioEstat 5.3 program. We evaluated the relationship between the groups and the factors and the success of pregnancy the odds ratio (OR) and chi-square test (p = 0.05). RESULTS: In the first analysis it was observed that the ISO 5/7 laboratory, there were successful in the formation of embryos and the conventional O , CI - 2: 0.24, p: 0.81). 5/7 96.6% ISO laboratory embryos were generated A or B, since the conventional laboratory, 90.4% were A or B. The pregnancy success in the laboratory I O was , and conventional laboratory O CI to 2: 2,24; p: 0.13). The second correlation was found with pregnancy failure female factors: having more than 40 years (OR 6.04, CI: 1.34 to 27.08; p: 0.010), higher infertility time 97 months (OR: 4.49, CI: 1.65 to 12, .21; p: 0.00) and have endometrial thickness of less than 10mm (OR: 5.42, CI: 2.44 to 12.05; p:0.001). The male factors with correlation were: oligozoospermia (OR:3,35; IC:1,41-7,92; p:0,010) e teratozoospermia (OR:4,14; IC:1,89-9,07; p:0,010).Microbiological contamination was found in 11.06% of semen samples. CONCLUSIONS: There was no statistical difference between the results of the two laboratories, however we observed a trend of better quality embryos in ISO 5/7 laboratory. It was concluded that the patients attended the LabRep/HC/UFG, present a great heterogeneity of clinical profiles and different reproductive characteristics. It shows how a major challenge that encourages the ongoing investment in cutting edge technology and processes, as well as constant improvement of the multidisciplinary team that make up the lab.
INTRODUÇÃO: A frequência de produção de embriões e sucesso na gravidez são os principais parâmetros usados para verificar a qualidade de laboratórios de reprodução humana. OBJETIVO: Comparar o sucesso na produção e qualidade de embriões, taxa de sucesso e fatores relacionados a gravidez no LabRep/HC/UFG, antes de profundas adequações estrututurais, quando era classificado como laboratório convencional e após as adequaçãos, quando passou a ser classificado como um laboratório ISO 5/7 e os fatores relacionados ao sucesso da fertilização. MÉTODO: O desenho do estudo foi do tipo caso controle. Os dados foram inseridos no programa Epi-Info 3.3.2 ® e analisados no programa BioEstat 5.3 ®. Foram avaliadas a relação entre os grupos e dos fatores e o sucesso da gravidez pelo odds ratio (OR) e qui-quadrado (p=0,05). O estudo se deu no Laboratório de Reprodução Humana do HC/UFG Goiânia-Goiás. Foram pesquisadas informações de 278 ciclos de mulheres que submeteram a uer técnica de FIV, ICSI E IIU, como tratamento de Reprodução Humana Assistida no período do estudo. O trabalho foi dividido em três artigos para melhor compreensão dos resultados. No primeiro artigo realizou-se uma revisão bibliográfica sobre relação entre alterações bioquímicas, ambientais e microbiológicas e o sucesso da técnica de fertilização in vitro. O segundo artigo avaliou a qualidade embrionária e o terceiro, os fatores de risco com capacidade de interferir no sucesso da gestação. Na primeira análise foram pesquisadas: clivagem do embrião, resultado do βHCG, qualidade embrionária e a contaminação microbiológica dos meios de cultivos de embriões. Na segunda, foram avaliados o tamanho dos folículos por mulher, quantidade de oócitos aspirados, captados, inseminados e injetados, esquema de estimulação ovariana, infecções maternas, período de infertilidade e qualidade espermática. RESULTADOS: No primeiro trabalho científico onde comparou-se o sucesso na produção e qualidade de embriões, taxa de sucesso e contaminação microbiológica nos meios de cultura onde os embriões foram cultivados antes das adequações estrututurais, quando era classificado como laboratório convencional e após as adequaçãos, quando passou a ser classificado como um laboratório ISO 5/7, foi observado que no laboratório ISO 5/7, houve 74,1% de sucesso na formação de embriões e no convencional 67,8% (OR:1,30; IC:0,47-3,61; אּ2:0,24; p:0,81). No laboratório ISO 5/7 96,6% dos embriões gerados eram A ou B, já no laboratório convencional, 90,4% eram A ou B. O sucesso de gravidez no laboratório ISO 5/7 foi de 22,8% e no laboratório convencional de 36,2% (OR:1,9; IC: 0,81-4,52; אּ 2: 2,24; p: 0,13). No segundo trabalho científico onde avaliou-se os fatores relacionados a gravidez no LabRep/HC/UFG, foi encontrado correlação do insucesso de gravidez com os fatores femininos: ter mais de 40 anos (OR: 6,04; IC: 1,34-27,08; p:0,010), tempo de infertilidade superior a 97 meses (OR: 4,49; IC: 1,65-12,.21; p:0,001) e possuir endométrio com espessura inferior a 10mm (OR: 5,42; IC: 2,44-12,05; p:0,001). Os fatores masculinos com correlação foram: oligozoospermia (OR: 3,35; IC: 1,41-7,92; p:0,010), teratozoospermia (OR: 4,14; IC: 1,89-9,07; p:0,010). Foi encontrado contaminação microbiológica em 6.11% das amostras de sêmen. CONCLUSÕES: No primeiro trabalho científico foi possível concluir que não houve diferença estatística entre os resultados dos entre os dois laboratórios. No segundo trabalho científico concluiu-se que os fatores relacionados ao insucesso do tratamento de reprodução assistida encontrados foram: idade superior a 40 anos, tempo de infertilidade superior a 96 meses e espessura endometrial inferior a 10mm e presença de sêmen de baixa qualidade.
Taylor, C. J. "Juvenile onset coeliac disease in Liverpool : A reappraisal; I Epidemiology and clinical and laboratory risk factors; II The diagnostic value of circulating antibodies to cow's milk proteins and gliadin, detected by ELISA." Thesis, University of Liverpool, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383577.
Повний текст джерелаKoduri, Gouri. "Long term outcomes from an inception cohort, ERAS (Early Rheumatoid Arthitis Study). A proslective study of the frequency, clinical and laboratory risk factors for the cardiovascular disease, all-cause mortality and comorbidity in early RA." Thesis, University of East Anglia, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588762.
Повний текст джерелаKoch, David R. "Field and laboratory application of a gas chromatograph low thermal mass resistively heated column system in detecting traditional and non-traditional chemical warfare agents using solid phase micro-extraction /." Download the thesis in PDF, 2005. http://www.lrc.usuhs.mil/dissertations/pdf/Koch2005.pdf.
Повний текст джерелаGiusti, Giovanni 1984. "Three essays in experimental economics." Doctoral thesis, Universitat Pompeu Fabra, 2014. http://hdl.handle.net/10803/284453.
Повний текст джерелаAquesta tesi conté tres assaigs. En el primer assaig (conjunt amb Janet Jiang i Xiping Xu) estudiem la bombolla de preus d’actius en un experiment de laboratori. Introduint els pagaments d’interessos en efectiu separem l’efecte del cost d’oportunitat de comerciar de la trajectòria del valor fonamental de l’actiu. Els resultats mostren que la trajectòria del valor fonamental juga un paper molt crític. En el segon assaig (conjunt amb Charles Noussair i Hans-Joachim Voth) estudiem en un laboratori la importància de diverses característiques institucionals històriques que van caracteritzar la “bombolla dels mars del sud”. El nostre principal descobriment és que el “swap” de deute per accions és l’únic gran contribuïdor per l’explosió del preu de les accions. En el tercer assaig estudiem en un experiment com diferents dinàmiques de preu fet com a incentiu monetari afecten la prestació d’esforç dels participants. El nostre principal descobriment indica que una disminució del preu fet després d’un increment té efectes perjudicials per a la prestació d’esforç dels participants.
Smith, Abraham Jeffrey. "Development and Application of Aquatic Toxicology Studies for the Assessment of Impacts Due to Chemical Stressors Using Non-Standard Indigenous Organisms." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3709.
Повний текст джерелаManivasagam, Karnica. "COMPARISON OF WRIST VELOCITY MEASUREMENT METHODS: IMU, GONIOMETER AND OPTICAL MOTION CAPTURE SYSTEM." Thesis, KTH, Medicinteknik och hälsosystem, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-287178.
Повний текст джерелаUpprepade uppgifter, besvärliga hand- / handledsställningar och kraftfulla ansträngningar är kända riskfaktorer för arbetsrelaterade muskuloskeletala störningar (WMSD) i hand och handled. WMSD är en viktig orsak till lång frånvaro, produktivitetsförlust, löneförlust och individuellt lidande. För närvarande tillgängliga bedömningsmetoder för hand / handledsrörelser har begränsningarna att vara felaktiga, t.ex. när du använder självrapporter eller observationer, eller dyra och resurskrävande för följande analyser, t.ex. när du använder elektrogoniometrarna. Därför finns det ett behov av en riskbedömningsmetod som är enkel att använda och som kan användas av både forskare och utövare för att mäta handledens vinkelhastighet under en 8-timmars arbetsdag. Wearable Inertial Measuring Units (IMU) i kombination med mobiltelefonapplikationer ger möjlighet till en sådan metod. För att kunna använda IMU i fältet för att bedöma handledens hastighet för olika arbetsuppgifter måste metodens noggrannhet undersökas. Därför genomfördes detta laboratorieexperiment för att jämföra en ny IMU-baserad metod med den traditionella goniometern och det vanliga optiska rörelsefångningssystemet. Laboratorieexperimentet utfördes på tolv deltagare. Tre standardhandrörelser, inklusive hand / handledsrörelse av Flexion-extension (FE), Deviation och Pronation-supination (PS) vid 30, 60, 90 beat-per-minut (bpm) och tre simulerade arbetsuppgifter utfördes. Vinkelhastigheten för de tre metoderna vid 50: e och 90: e percentilen beräknades och jämfördes. Det genomsnittliga absoluta felet och korrelationskoefficienten analyserades för att jämföra metoderna. Ökning av fel observerades med ökning av hastighet/bpm under standardhandrörelserna. För standardhandrörelser hade jämförelsen mellan IMUbyaxis och Goniometer den minsta skillnaden och högsta korrelationskoefficienten. För simulerade arbetsuppgifter var skillnaden mellan goniometer och optiskt system den minsta. För simulerade arbetsuppgifter var dock skillnaderna mellan de jämförda metoderna i allmänhet mycket större än de vanliga handrörelserna. Den IMUbaserade metoden anses ha potential jämfört med traditionella mätmetoder. Ändå behöver det förbättras för att kunna användas för riskbedömning på fältet.
González, Lao Elisabet. "Gestión de los riesgos en los laboratorios de urgencias y su impacto en la seguridad del paciente." Doctoral thesis, Universitat Autònoma de Barcelona, 2017. http://hdl.handle.net/10803/403805.
Повний текст джерелаDuring de last 4 years, a study has been taken on the Risk Management in Laboratories of Emergency and its impact in the Patient Safety. The principal aim of the above mentioned study is to improve the Patient Safety and to promote the Culture of Patient Safety. The starting point is to study all the possible risks that can take place in these laboratories and to plan preventive and corrective actions that will form part of the Risk Management. Mainly, the study consists of 4 parts: - Identification of the possible failure modes in the processes of the laboratories. The applied is the Failures Modal and Effects Analysis (FMEA) that allows us to identify all the possible potential risks and to implement preventive actions. - The control of the critical points in the processes of the laboratories is realized with the application of the Failure Reporting, Analysis and Corrective Actions (FRACAS), which allows us to detect the mistakes that happen and to implement corrective actions. - Evaluation the Culture of the Patient Safety among the professionals of Emergency Laboratories and the professionals of the services with major demand in the Emergency Laboratory. The essential among training actions are planning to relieve to identify deficiencies. - Recommendation of preventive and corrective actions for the potential or critical risks identified and detected mistakes. Implantation and evaluation some of the most relevant actions. All these actions of improvement will be gathered in the Risk Management and from its evaluation it will be possible to determine the degree of efficiency. This study has allowed us to implement the Risk Management in the Emergency Laboratories and to create a model to be checked out in the future to improve Patient Safety, as well as to spread the culture and increase the competence of the professionals in relation with this topic.
Iglesias, Martin Casals. "O comportamento do investidor brasileiro na alocação de ativos." reponame:Repositório Institucional do FGV, 2006. http://hdl.handle.net/10438/2080.
Повний текст джерелаO objetivo deste trabalho é analisar a alocação de investimentos no mercado acionário brasileiro, utilizando a teoria do prospecto de Tversky e Kahneman (1979) e o conceito de Aversão a Perdas Míope (Myopic Loss Aversion) proposto por Benartzi e Thaler (1995). Foram levantados através de experimento de laboratório os parâmetros da função de valor e da função de ponderação de probabilidades da teoria do prospecto e foi verificada a alocação de investimentos entre ações e renda fixa que maximizam a utilidade. Chegamos à conclusão que o total de recursos atualmente direcionados ao mercado de ações no Brasil, que é de aproximadamente 2,7% para pessoas físicas e de 6,0% para pessoas jurídicas, é compatível com a teoria do prospecto.
The objective of this study is to analyze the investment allocation in the Brazilian stock market, using Tversky and Kahneman’s prospect theory (1979) and the concept of myopic loss aversion proposed by Benartzi and Thaler (1995). We run a laboratory experiment to obtain the parameters of the value function and the probability weighting function of the prospect theory and identify the allocation that maximizes utility in the Brazilian Market We conclude that the actual allocation of investment in the stock market, of around 2.7% for individuals and around 6% for all the segments, is in accordance with the prospect theory.
Junior, Geraldo de Oliveira Silva. "Restrição proteica materna e alteração do desenvolvimento das artérias coronárias em camundongos." Universidade do Estado do Rio de Janeiro, 2011. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=4785.
Повний текст джерелаO desenvolvimento da programação fetal é considerado um importante fator de risco para doenças não-transmissíveis da vida adulta, incluindo doença cardíaca coronariana. Com o objetivo de investigar a associação entre nutrição materna e o desenvolvimento das artérias coronárias (AC) em embriões de camundongos estadiados; embriões de camundongos C57BL/6 nos estádios de 16-23 foram retirados de mães alimentadas com dietas de proteína normal (NP) ou de baixa proteína (LP), e as AC foram estudadas. Embora os embriões LP possuam massa corporal menor, entretanto tinham taxas de crescimento cardíaco maior, quando comparados com os embriões NP. O Plexo subepicárdico foi observado no início do período pós-somítico (estádio 16) de embriões NP, enquanto que nos embriões LP apenas no estádio 17 (P <0,01), persistindo até o estádio 18 (P <0,01). As artérias coronárias foram detectadas inicialmente no estádio18 dos embriões NP, já nos embriões LP foram encontradas a partir do estádio 19 (P <0,01). Núcleos apoptóticos foram observados em torno do anel aórtico peritruncal no estádio 18 em embriões NP e LP. Células FLK1+ (Fetal Liver Kinase 1 = VEGFr2 = Vascular Endothelial Growth Factor Receptor 2) apresentaram uma distribuição homogênea nos embriões NP já no estádio 18, enquanto uma distribuição semelhante nos embriões LP foi visto apenas nos estádios 22 e 23. A restrição proteica materna em camundongos leva a um atraso no crescimento do coração no período embrionário modificando o desenvolvimento do plexo peritruncal subepicárdica e diminuindo a taxa de apoptose na região do futuro orifício coronariano.
Programming of fetal development is considered to be an important risk factor for non-communicable diseases of adulthood, including coronary heart disease (CHD). Aiming to investigate the association between maternal nutrition and the development of the coronary arteries (CA) in staged mice embryos, C57BL/6 mice embryos from stages 16 to 23 were taken from mothers fed a normal protein (NP) or low protein (LP) diet, and the CA were studied. Although the LP embryos had lower masses, they had faster heart growth rates when compared to the NP embryos. The subepicardial plexuses were observed earlier in the NP embryos (stage 20) than in the LP ones (stage 22) (P<0.01). Apoptotic nuclei were seen around the aortic peritruncal ring beginning at stage 18 in the NP and LP embryos. FLK1+ (fetal liver kinase 1 = VEGFr2 or vascular endothelial growth factor receptor 2) cells had a homogeneous distribution in the NP embryos as early as stage 18, whereas a similar distribution in the LP embryos was only seen at stages 22 and 23. Maternal protein restriction in mice leads to a delay in the growth of the heart in the embryonic period modifying the development of the subepicardial peritruncal plexus and the apoptosis in the future coronary orifice region.
Dewan, P. A. (Patrick Arthur). "Vesicoureteric reflux : clinical and laboratory research including investigation of the role and risks of plastics / P.A. Dewan." 1999. http://hdl.handle.net/2440/19385.
Повний текст джерела271 leaves : col. ill. ; 30 cm.
Title page, contents and abstract only. The complete thesis in print form is available from the University Library.
Indicates that injections under the ureteric orifice can cure VUR and that the tissue response to the plastics becomes quiescent. Research into embolisation from solid implants from intravenous tubing and the possibility of antibody formation to implanted plastics is also included. A model for fetal VUR has been developed to clarify focus of the uncertainity about reflux disease.
Thesis (Ph.D.)--University of Adelaide, Dept. of Paediatrics, 1999
Lee, Shu-Hua, and 李淑華. "Risk Factors of Patient Safety in Medical Laboratory." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/95405543626654268974.
Повний текст джерела國立臺南大學
經營與管理學系科技管理碩士在職專班
102
This study aims to evaluate the risk factors of patient safety in medical laboratory of large-scaled hospitals in Taiwan, with application of theories of human factor engineering, Delphi method and Analytic Hierarchy Process method (AHP). The priorities of dimensions in the descending order are: the ability of the Medical Technologist (MT), the interaction between medical personnel and software, the interaction between medical personnel and hardware and the interaction between medical personnel. Among the 15 risk factors, deficiency of profession knowledge and skills of Medical Technologist ranked first. The second important risk factor was inadequate attitude toward medical errors. The third important risk factor was deficiency of Medical Technologist. The fourth important risk factor was Shift work. The fifth important risk factor was undesirable quality instruments. This study found that MT is a very professional medical staff, most important risk factor are MT and medical equipment. The countermeasures include enhance MT professional knowledge and skills, knowledge of patient safety and the harm risk, humane shift work patterns and purchasing better quality and stability equipment. The result of this study could be the reference of incident and strategy at medical laboratory.