Дисертації з теми "Kinetic Design"
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Wenning, Matthew R. "Kinematic and kinetic differences in the barbell squat wearing two different types of shoes." Virtual Press, 2005. http://liblink.bsu.edu/uhtbin/catkey/1328122.
Повний текст джерелаSchool of Physical Education, Sport, and Exercise Science
Po-Yi, Wu. "Affective and kinetic design in Brahms' duo sonatas." Thesis, King's College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.431173.
Повний текст джерелаHuan, Xun. "Accelerated Bayesian experimental design for chemical kinetic models." Thesis, Massachusetts Institute of Technology, 2010. http://hdl.handle.net/1721.1/59678.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (p. 129-136).
The optimal selection of experimental conditions is essential in maximizing the value of data for inference and prediction, particularly in situations where experiments are time-consuming and expensive to conduct. A general Bayesian framework for optimal experimental design with nonlinear simulation-based models is proposed. The formulation accounts for uncertainty in model parameters, observables, and experimental conditions. Straightforward Monte Carlo evaluation of the objective function - which reflects expected information gain (Kullback-Leibler divergence) from prior to posterior - is intractable when the likelihood is computationally intensive. Instead, polynomial chaos expansions are introduced to capture the dependence of observables on model parameters and on design conditions. Under suitable regularity conditions, these expansions converge exponentially fast. Since both the parameter space and the design space can be high-dimensional, dimension-adaptive sparse quadrature is used to construct the polynomial expansions. Stochastic optimization methods will be used in the future to maximize the expected utility. While this approach is broadly applicable, it is demonstrated on a chemical kinetic system with strong nonlinearities. In particular, the Arrhenius rate parameters in a combustion reaction mechanism are estimated from observations of autoignition. Results show multiple order-of-magnitude speedups in both experimental design and parameter inference.
by Xun Huan.
S.M.
Parkes, Amanda Jane. "Topobo : a gestural design tool with kinetic memory." Thesis, Massachusetts Institute of Technology, 2004. http://hdl.handle.net/1721.1/28768.
Повний текст джерелаThesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2004.
The modeling of kinetic systems, both in physical materials and virtual simulations, provides a methodology to better understand and explore the forces and dynamics of our physical environment. The need to experiment, prototype and model with programmable kinetic forms is becoming increasingly important as digital technology becomes more readily embedded in physical structures and provides real-time variable data the capacity to transform the structures themselves. This thesis introduces Topobo, a gestural design tool embedded with kinetic memory--the ability to record, playback, and transform physical motion in three dimensional space. As a set of kinetic building blocks, Topobo records and repeats the body's gesture while the system's peer-to-peer networking scheme provides the capability to pass and transform q gesture. This creates a means to represent and understand algorithmic simulations in a physical material, providing a physical demonstration of how a simple set of rules can lead to complex form and behavior. Topobo takes advantage of the editability of computer data combined with the physical immediacy of a tangible model to provide a means for expression and investigation of kinetic patterns and processes not possible with existing materials.
Amanda J. Parkes.
S.M.
Abraham, Thomas Kannankara. "Kinetic bounds on attainability in the reactor synthesis problem." Connect to resource, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1126791863.
Повний текст джерелаTitle from first page of PDF file. Document formatted into pages; contains xvi, 190 p.; also includes graphics (some col.). Includes bibliographical references (p. 182-190). Available online via OhioLINK's ETD Center
Zhou, Mingxia. "First-principles based micro-kinetic modeling for catalysts design." Diss., Kansas State University, 2018. http://hdl.handle.net/2097/38608.
Повний текст джерелаDepartment of Chemical Engineering
Bin Liu
Efficient and selective catalysis lies at the heart of many chemical reactions, enabling the synthesis of chemicals and fuels with enormous societal and technological impact. A fundamental understanding of intrinsic catalyst properties for effective manipulation of the reactivity and selectivity of industrial catalysts is essential to select proper catalysts to catalyze the reactions we want and hinder the reactions we do not want. The progress in density functional theory (DFT) makes it possible to describe interfacial catalytic reactions and predict catalytic activities from one catalyst to another. In this study, water-gas shift reaction (WGSR) was used as a model reaction. First-principles based micro-kinetic modeling has been performed to deeply understand interactions between competing reaction mechanisms, and the relationship with various factors such as catalyst materials, structures, promoters, and interactions between intermediates (e.g., CO self-interaction) that govern the observed catalytic behaviors. Overall, in this thesis, all relevant reaction mechanisms in the model reaction on well-defined active sites were developed with first-principles calculations. With the established mechanism, the promotional effect of K adatom on Ni(111) on WGSR compared to the competing methanation was understood. Moreover, the WGSR kinetic trend, with the hydrogen production rate decreasing with increasing Ni particle diameters (due to the decreasing fractions of low-coordinated surface Ni site), was reproduced conveniently from micro-kinetic modeling techniques. Empirical correlations such as Brønsted-Evans-Polanyi (BEP) relationship for O-H, and C-O bond formation or cleavage on Ni(111), Ni(100), and Ni(211) were incorporated to accelerate computational analysis and generate trends on other transition metals (e.g., Cu, Au, Pt). To improve the numerical quality of micro-kinetic modeling, later interactions of main surface reaction intermediates were proven to be critical and incorporated successfully into the kinetic models. Finally, evidence of support playing a role in the enhancement of catalyst activity and the impact on future modeling will be discussed. DFT will be a powerful tool for understanding and even predicting catalyst performance and is shaping our approach to catalysis research. Such molecular-level information obtained from computational methods will undoubtedly guide the design of new catalyst materials with high precision.
Gooch, S. D. "Design and mathematical modelling of the kinetic sculpture Blade." Thesis, University of Canterbury. Mechanical Engineering, 2001. http://hdl.handle.net/10092/7844.
Повний текст джерелаColes, Thomas Michael Kyte. "Model simplification of chemical kinetic systems under uncertainty." Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/65183.
Повний текст джерелаThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.
Cataloged from student submitted PDF version of thesis.
Includes bibliographical references (p. 103-108).
This thesis investigates the impact of uncertainty on the reduction and simplification of chemical kinetics mechanisms. Chemical kinetics simulations of complex fuels are very computationally expensive, especially when combined with transport, and so reduction or simplification must be used to make them more tractable. Existing approaches have been in an entirely deterministic setting, even though reaction rate parameters are generally highly uncertain. In this work, potential objectives under uncertainty are defined and then a number of studies are made in the hope of informing the development of a new uncertainty-aware simplification scheme. Modifications to an existing deterministic algorithm are made as a first step towards an appropriate new scheme.
by Thomas Michael Kyte Coles.
S.M.
Fox, Justin M. 1981. "Fully-kinetic PIC simulations for Hall-effect thrusters." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/41733.
Повний текст джерелаIncludes bibliographical references (p. 173-177).
In recent years, many groups have numerically modeled the near-anode region of a Hall thruster in attempts to better understand the associated physics of thruster operation. Originally, simulations assumed a continuum approximation for electrons and used magnetohydrodynamic fluid equations to model the significant processes. While these codes were computationally efficient, their applicability to non-equilibrated regions of the thruster, such as wall sheaths, was limited, and their accuracy was predicated upon the notion that the energy distributions of the various species remained Maxwellian at all times. The next generation of simulations used the fully-kinetic particle-in-cell (PIC) model. Although much more computationally expensive than the fluid codes, the full-PIC codes allowed for non-equilibrated thruster regions and did not rely on Maxwellian distributions. However, these simulations suffered for two main reasons. First, due to the high computational cost, fine meshing near boundaries which would have been required to properly resolve wall sheaths was often not attempted. Second, PIC is inherently a statistically noisy method and often the extreme tails of energy distributions would not be adequately sampled due to high energy particle dissipation. The current work initiates a third generation of Hall thruster simulation. A PIC-Vlasov hybrid model was implemented utilizing adaptive meshing techniques to enable automatically scalable resolution of fine structures during the simulation. The code retained the accuracy and versatility of a PIC simulation while intermittently recalculating and smoothing particle distribution functions within individual cells to ensure full velocity space coverage. A non-Monte Carlo collision technique was also implemented to reduce statistical noise.
(cont.) This thesis details the implementation and thorough benchmarking of that new simulation. The work was conducted with the aid of Delta Search Labs' supercomputing facility and technical expertise. The simulation was fully-parallelized using MPI and tested on a 128 processor SGI Origin machine. We gratefully acknowledge that funding for portions of this work has been provided by the United States Air Force Research Laboratory and the National Science Foundation.
by Justin M. Fox.
S.M.
Korkmaz, Koray Arkon Cemal. "An analytical study of the design potentials in kinetic architecture/." [s.l.]: [s.n.], 2004. http://library.iyte.edu.tr/tezler/doktora/mimarlik/T000485.doc.
Повний текст джерелаBenson, Brian C. "Design and Analysis of a Rapid Kinetic Energy Transmission Mechanism." Digital WPI, 2011. https://digitalcommons.wpi.edu/etd-theses/327.
Повний текст джерелаBrown, Ashlie (Ashlie M. ). "Building KiMoSin : design requirements for kinetic interfaces in protein education." Thesis, Massachusetts Institute of Technology, 2007. http://hdl.handle.net/1721.1/40396.
Повний текст джерелаIncludes bibliographical references (leaves 18-19).
Design guidelines for tools to enhance protein education are developed and applied to a prototype tool. A literature search and personal experience suggest kinetic, tangible models fill the current gaps in protein education. Thirty-six personal interviews with biology instructors and students set a mandate for three design guidelines for appropriate kinetic, tangible tools. The guidelines - simplicity, accuracy, and intuition - form a simple mantra to guide protein education tool design. The guidelines are then used to develop the prototype of an educational model of kinesin, a simple and vital motor protein. Application of these guidelines should result in design that provides students an interactive medium to discover the world of proteins. The prototyped kinesin model, nicknamed KiMoSin, shows promise of fulfilling that goal.
by Ashlie Brown.
S.B.
Fox, Michael A. (Michael Allan). "Novel affordances of computation to the design processes of kinetic structures." Thesis, Massachusetts Institute of Technology, 1996. http://hdl.handle.net/1721.1/10995.
Повний текст джерелаIncludes bibliographical references (leaves 44-45).
This paper is a discourse into the relationship between the process, computational tools and the role which symbolic structure can play in both. I argue the relationship of the process and tools is dialectic, whereby the tools we utilize in design develop new heuristics, the methodologies in tum, if reflectively understood, can be more aptly facilitated through the development of novel tools. The tools and the process then evolve together. A theory is laid out exploring the human visual information processing systems pertinence to the limitations in mental three-dimensional imaging and transformation operations relevant to the operations of drawing and mental visualization within the architectural design processes, substantiating the designers "necessity" to d raw (by traditional means, but more importantly here, through the inclusive integration of CAD within the process). The "necessity" to draw is explored as a re-presentational process to the visual system predicated upon the existence of a structured internal "library" of diagram-like representations. I argue that the ways we utilize such idiosyncratic libraries is predicated upon the ways in which we go about structuring the perceived "experienced" world around us into "symbol systems". And finally, the ways we utilize our reflective understanding of the heuristic transformations of these "symbols" within the design process in the context of a CAD environment are explored as a means to an enhanced understanding of that which is being designed and consequently as a vehicle for the development of future CAD systems to better facilitate such methodologies of designing. A personal design process of several kinetic structures is carried out in order to arrive at a localized process analysis within computer-aided design environment. Through an interactive, reflective process analysis, conclusions are drawn as to the affordances and limitations of such tools as suggestive of the operations a CAD environment might perform so as to better foster future methodologies of designing. The design "experiments" are utilized as a vehicle to understand the process. Specifically three kinetic projects are exploited for the prototypical "operations" they display. When difficulties or mental limitations are encountered with the operations, specific "tools" are developed to facilitate the limitation or to overcome the problem.
by Michael A. Fox.
M.S.
Kislyak, Anastasia. "In-depth kinetic understanding and design of [4+4] anthracene photocycloadditions." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/226945/1/Anastasia_Kislyak_Thesis.pdf.
Повний текст джерелаWierzbicki, Madalina Nicoleta. "Topologies and design methods for folding kinetic structures : expanding the architectural paradigm." Thesis, University of British Columbia, 2014. http://hdl.handle.net/2429/45748.
Повний текст джерелаAllcock, Gillian C. "The statistical aspects of the analysis and design of enzyme kinetic studies." Thesis, University of Newcastle Upon Tyne, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366536.
Повний текст джерелаNaifar, Slim. "Model Based Design of a Magnetoelectric Vibration Converter from Weak Kinetic Sources." Universitätsverlag Chemnitz, 2018. https://monarch.qucosa.de/id/qucosa%3A32774.
Повний текст джерелаDie größte Herausforderung bei der Konstruktion von Vibrations-Energiewandlern ist die Optimierung der gewonnenen Energie im Verhältnis zur angewandten Anregung, um trotz schwacher Umgebungsenergiequellen einen hohen Wirkungsgrad zu erreichen. Ein vielversprechendes Prinzip von Vibrationswandlern ist die Magnetoelektrizität aufgrund der hervorragenden Eigenschaften von magnetostriktiven und piezoelektrischen Verbundwerkstoffen, die interessante Möglichkeiten bieten, Energie aus niederfrequenten Schwingungen mit kleinen Amplituden zu gewinnen. Bei diesen Wandlern ist die Sicherstellung hoher Verformungen in den magnetostriktiven Schichten, die Verbesserung der magnetisch-mechanischen und der elektromechanischen Kopplungen für die Optimierung des Energieertrages sehr wichtig. Diese Arbeit zielt in erster Linie auf die Entwicklung eines modellbasierten Entwurfs für magnetoelektrische (ME) Wandler ab. Basierend auf einem umfassenden Verständnis des komplexen Energieflusses in magnetoelektrischen Wandlern werden mehrere Entwurfsparameter untersucht. So wird beispielsweise die Magnetostriktion in einer Terfenol-D-Platte mittels Rasterkraftmikroskopie unter ähnlichen Bedingungen untersucht wie in magnetoelektrischen Wandlern. Dabei wurde eine neuartige Messmethode erfolgreich entwickelt, um die Entwicklung von magnetischen Domänen zu erfassen und die Deformation in einer Terfenol-D-Platte als Reaktion auf extern ungleichmäßig angelegte Magnetfelder zu messen. Darüber hinaus wird ein Finite-Elemente-Modell entwickelt, um die induzierte Spannung im ME-Wandler als Reaktion auf die Verschiebung des Magneten vorherzusagen, welches auf der Grundlage von Atomkraftmikroskopie Messungen korrigiert und für den Entwurf des Energiewandlers verwendet wird. Das vorgestellte dreidimensionale Modell berücksichtigt das nichtlineare Verhalten der magnetostriktiven und piezoelektrischen Materialien. Zusätzlich werden drei neuartige Wandler mit unterschiedlichen Magnetkreisen nach dem Lindstedt-Poincaré Verfahren konzipiert und analytisch analysiert. Die Auswirkungen der Strukturparameter, wie die nichtlinearen Magnetkräfte, die Magnetfeldverteilung und die Resonanzfrequenz, werden diskutiert und die elektrischen Ausgangsleistungen der drei ausgelegten Wandler ausgewertet. Um die mechanische und elektrische Kopplung zwischen der piezoelektrischen und der magnetostriktiven Schicht zu verbessern, wird eine bei Raumtemperatur prozessierbare Verbindungstechnik vorgeschlagen, bei der leitfähige Nanokomposite verwendet werden. Zwei magnetoelektrische Wandler werden basierend auf dieser Technik mit einer Konzentration von 1 wt.% und 2 wt.% an mehrwandigen Kohlenstoff-Nanoröhren in Epoxidharz hergestellt. Ein weiterer magnetoelektrischer Wandler wurde zu Vergleichszwecken mit einer klassischen Technik hergestellt. Für die Validierung des Entwurfes wird eine Reihe von Demonstratoren entsprechend den Simulations- und Optimierungsergebnissen konstruiert und gefertigt. Der vorgeschlagene Entwurf besteht aus einem Trägerbalken, einem Magnetkreis mit mehreren Magnetanordnungen und einem magnetoelektrischen Wandler, der aus einer piezoelektrischen PMNT-Platte besteht, die mit zwei magnetostriktiven Terfenol-D-Schichten verbunden ist. Bei dieser Konstruktion werden externe Schwingungen in Magnetfeldänderungen umgewandelt, die auf die magnetostriktiven Schichten wirken und zu Verformungen führen, die direkt auf die piezoelektrische Schicht übertragen werden. Die Wandler werden unter harmonischen Anregungen und mit realen Schwingungsprofilen getestet, die von einer künstlichen Schwingungsquelle reproduziert werden. Verschiedene Parameter wurden experimentell untersucht, darunter die magnetischen Kräfte zwischen dem Wandler und dem Magnetkreis sowie die verwendete Verbindungstechnik. Die Abstimmung der Resonanzfrequenz des ME-Wandlers erfolgt ebenfalls über ein einfaches Schrauben-Mutter-System, das es ermöglicht, die relative Position und damit die magnetischen Kräfte zwischen Magnetkreis und Wandler zu steuern. Der magnetoelektrische Wandler, der mit einer Konzentration von 2 wt.% mehrwandiger Kohlenstoff-Nanoröhrchen verbunden ist, zeigt bessere Ausgangsleistungen als die beiden anderen ME-Wandler bei ähnlichen Anregungen. Eine maximale Ausgangsleistung von 2,42 mW wird bei 1 mm angelegter Vibration bei 40 Hz erreicht. Diese Leistung stellt eine Verbesserung von mindestens 20 % im Vergleich zu anderen magnetoelektrischen Schwingungsumrichtern dar, welche mit einem einzigen ME-Wandler bei vergleichbaren Anregungen getestet werden.
Hone, Christopher Andrew. "Evolution of kinetic motifs through rate-based experimental design in flow reactors." Thesis, University of Leeds, 2016. http://etheses.whiterose.ac.uk/12202/.
Повний текст джерелаSandström, Anders G., Ylva Wikmark, Karin Engström, Jonas Nyhlén, and Jan-E. Bäckvall. "Combinatorial reshaping of the Candida antarctica lipase A substrate pocket for enantioselectivity using an extremely condensed library." Stockholms universitet, Institutionen för organisk kemi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-74997.
Повний текст джерелаAl, Wahabi Saeed M. H. "Conversion of methanol to light olefins on SAPO-34: kinetic modeling and reactor design." Texas A&M University, 2003. http://hdl.handle.net/1969.1/1579.
Повний текст джерелаAdams, Jonathan Weldon. "Kinetic assay of T7 activity on mutant promoters : method development and experimental design." Thesis, Georgia Institute of Technology, 1995. http://hdl.handle.net/1853/29908.
Повний текст джерелаSaeed, Muhammad Tariq. "Application of kinetic models to the design of liquid-liquid extraction spray columns." Thesis, Imperial College London, 1989. http://hdl.handle.net/10044/1/47638.
Повний текст джерелаParkes, Amanda Jane. "Phrases of the kinetic : dynamic physicality as a dimension of the design process." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/51661.
Повний текст джерелаIncludes bibliographical references (p. 161-167).
At its core, the concept of Tangible Interfaces leverages the idea of using the movement of the body as an inherent part of the human side of a human-computer interaction, assuming that bodily engagement and tactile manipulation can facilitate deeper understanding and more intuitive experiences. However, as an interaction principle in our era of digital design, motion construction and control has been underutilized and little examined as a design tool, leaving open the possibilities of motion's natural ability to draw our attention, provide physical feedback, and convey information through physical change. This dissertation postulates that the ability to experiment, prototype, and model with programmable kinetic forms is becoming increasingly important as digital technology becomes more readily embedded in our objects and environments and need for tools and systems with which to create, manipulate and finesse motion in response to computational and material input remains an under-developed design area. This thesis aims to establish principles of kinetic design through the exploration of two approaches to motion construction and manipulation: motion prototyping as a methodology for design thinking, learning and communication and physically dynamic state memory as a methodology for organic form finding and transformation in the design process.
(cont.) To demonstrate these aims, I present three interface systems: Topobo, a system for motion construction and dynamics physics education with children; Kinetic Sketchup, a system for motion construction and prototyping in architecture and product design; and Bosu, an augmented textile interface offering an experimental approach to digitally augmented organic form finding in fashion and product design.
Amanda Jane Parkes.
Ph.D.
Foster, Michael Scott. "Design, synthesis, kinetic analysis, molecular modeling, and pharmacological evaluation of novel inhibitors of peptide amidation." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2008. http://hdl.handle.net/1853/31816.
Повний текст джерелаCommittee Chair: Dr. Sheldon W. May; Committee Member: Dr. James C. Powers; Committee Member: Dr. Nicholas Hud; Committee Member: Dr. Niren Murthy; Committee Member: Dr. Stanley H. Pollock. Part of the SMARTech Electronic Thesis and Dissertation Collection.
Jovkar, Sayed. "Optimization of experimental design in Tracer kinetic models applied to Positron Emission Tomography and Autordiography." Thesis, McGill University, 1986. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=65387.
Повний текст джерелаLynas, John F. "The design, synthesis and kinetic characterisation of novel inhibitors of the serine and cysteine proteases." Thesis, Queen's University Belfast, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.318767.
Повний текст джерелаPoliakov, Anton. "Peptide-Based Inhibitors of Hepatitis C Virus NS3 Serine Protease: Kinetic Aspects and Inhibitor Design." Doctoral thesis, Uppsala universitet, Institutionen för naturvetenskaplig biokemi, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4127.
Повний текст джерелаBlauth, Florian [Verfasser], Jürgen [Gutachter] Stutzki, and Joachim [Gutachter] Hemberger. "Design and measurement of superconducting microwave kinetic inductance detectors / Florian Blauth ; Gutachter: Jürgen Stutzki, Joachim Hemberger." Köln : Universitäts- und Stadtbibliothek Köln, 2019. http://d-nb.info/1199004715/34.
Повний текст джерелаKassabian, Paul E. (Paul Edward) 1974. "On the design of a kinetic adaptive structural surface with reference to nature, form and simplicity." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/29568.
Повний текст джерелаIncludes bibliographical references (p. 89-90).
The central thrust of this thesis is that there is much to learn from Nature. What surrounds us, and has been with us from the beginning of time, still has many insights to offer, if we are only willing to look. In Nature, shape is cheaper than material. Forces and form are continuously linked and the concept of adaptability is central to survival. Many of our designs, in contrast, have been over-designed, unresponsive and unchangeable. This thesis covers how well thought through form can yield impressive benefits which, in combination with adaptability, can create structures that are efficient as well as beautiful. Specific forms in Nature are discussed as well relevant historical examples from the built environment; including new work in deployable structures. As an example of these concepts, a kinetic adaptive structural surface was designed and built. This responded to applied loads by actively changing its shape. The thesis concludes with a discussion on emergence as one of the ways ahead for structural design that involves distributed sensing and control.
Paul E. Kassabian.
S.M.
Critchfield, Brian L. "Statistical Methods For Kinetic Modeling Of Fischer Tropsch Synthesis On A Supported Iron Catalyst." Diss., CLICK HERE for online access, 2006. http://contentdm.lib.byu.edu/ETD/image/etd1670.pdf.
Повний текст джерелаSpencer, Timothy David. "Design of Len Lye's blade at the largest economic size." Thesis, University of Canterbury. Mechanical Engineering, 2014. http://hdl.handle.net/10092/9368.
Повний текст джерелаDaoudi, Gabriele Yunes. "Development of a Kinetic Energy Recovery System for a Rotary Turret Machine." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amslaurea.unibo.it/16595/.
Повний текст джерелаYu, Jie. "Novel swing arm mechanism design for trailing edge flaps on commercial airliner." Thesis, Cranfield University, 2008. http://dspace.lib.cranfield.ac.uk/handle/1826/9586.
Повний текст джерелаGerasimaitė, Rūta. "A directed evolution design of target specificity and kinetic analysis of conformational transitions in the HhaI methyltransferase." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110519_082240-87105.
Повний текст джерелаDNR citozino-5 metiltransferazės (MTazės) atpažįsta specifines DNR sekas ir katalizuoja metilgrupės pernešimą nuo kofaktoriaus AdoMet ant taikinyje esančio citozino. Šiame darbe nagrinėjami abu MTazių veikimo mechanizmo aspektai. Baltymų inžinerijos ir kryptingos evoliucijos metodais pašalinant vienos iš dviejų taikinio atpažinimo kilpų funkciją, MTazės HhaI atpažįstamas taikinys GCGC pakeistas į GCG. Dėl įvestų struktūros pakeitimų nauja unikalaus specifiškumo MTazė efektyviai katalizuoja ne tik metilo, bet ir didesnių grupių pernešimą nuo sintetinių kofaktoriaus analogų, ir gali tapti naudingu molekulinės biologijos įrankiu. Katalitinės reakcijos metu MTazės kilpa užsidaro, apglėbdama surištą DNR, o taikinio citozinas išsukamas iš DNR spiralės ir aktyvuojamas, kovalentiškai prisijungiant katalitiniam cisteinui. Šiems greitiems prieškatalitiniams procesams tirti buvo panaudotas naujas metodas, leidžiantis realiu laiku stebėti M.HhaI sąlygotą citozino išsukimą bei kovalentinę aktyvaciją, registruojant mažus UV absorbcijos pokyčius gamtinį substratą atitinkančioje DNR. Pirmą kartą parodyta, kad M.HhaI katalizuojamoje reakcijoje citozino išsukimas ir katalitinės kilpos užsidarymas vyksta sinchroniškai, o kovalentinė citozino aktyvacija ir metilgrupės pernešimas yra kinetiškai netapačios katalitinio ciklo stadijos. Kadangi naujasis metodas remiasi fundamentine nukleorūgščių savybe – hiperchrominiu efektu, todėl jis gali būti naudojamas ir kitų DNR bazę išsukančių baltymų... [toliau žr. visą tekstą]
Wilkinson, Nina. "An analysis of intrinsically disordered proteins using hidden Markov models and experimental design of stochastic kinetic models." Thesis, University of Newcastle upon Tyne, 2015. http://hdl.handle.net/10443/2846.
Повний текст джерелаZhu, Dongrui. "Glass Curtain Wall Retrofit Through Modular Kinetic Facade To Design Safe, Energy Efficient, Sustainable Urban Office High-rise Facade." University of Cincinnati / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1617108007657155.
Повний текст джерелаWatkins, Claire. "The Transformation of Electricity in my Brain." VCU Scholars Compass, 2004. http://scholarscompass.vcu.edu/etd/1062.
Повний текст джерелаSzost, Blanka Angelika. "Hydrogen trapping in bearing steels : mechanisms and alloy design." Thesis, University of Cambridge, 2013. https://www.repository.cam.ac.uk/handle/1810/244934.
Повний текст джерелаGarcia, Sandrine. "Experimental Design Optimization and Thermophysical Parameter Estimation of Composite Materials Using Genetic Algorithms." Diss., Virginia Tech, 1999. http://hdl.handle.net/10919/28076.
Повний текст джерелаPh. D.
Lamprecht, Florian [Verfasser], and Karsten [Akademischer Betreuer] Rippe. "Kinetic design of the JAK-STAT1 pathway and MYCN impact on cell cycle decisions in neuroblastoma / Florian Lamprecht ; Betreuer: Karsten Rippe." Heidelberg : Universitätsbibliothek Heidelberg, 2012. http://d-nb.info/1177040468/34.
Повний текст джерелаSmith, Stephanie A. "Design of a biological system to select for alterations in the key kinetic properties of ribulose 1,5-bisphosphate carboxylase/oxygenase (RubisCO) /." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1486463321626482.
Повний текст джерелаAhmed, Warsama. "Nitrifying Moving Bed Biofilm Reactors at Low Temperatures and Cold Shock Conditions: A Kinetic, Biofilm and Microbiome Study." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/41196.
Повний текст джерелаDlangamandla, Nkosikho. "Design of integrated processes for a second generation biorefinery using mixed agricultural waste." Thesis, Cape Peninsula University of Technology, 2018. http://hdl.handle.net/20.500.11838/2843.
Повний текст джерелаLignocellulosic biomass (agro-waste) has been recommended as the most promising feedstock for the production of bioalcohols, in the biofuel industry. Furthermore, agro-waste is well-known as the most abundant organic matter in the agricultural and forestry product processing industry. However, the challenge with utilizing agro-waste as a feedstock is its highly recalcitrant structure, which limits hydrolysis to convert the holocelluloses into fermentable sugars. Conventional pre-treatment methods such as dilute acid, alkaline, thermal, hot water and enzymatic, have been used in previous studies. The challenge with these conventional methods is the generation of residual toxicants during the pretreatment process, which inhibits a high bioalcohol yield, by reducing the microbial populations’ (fermenter) ability to be metabolically proficient during fermentation. Numerous studies have been developed to improve the engineered strains, which have shown to have an ability to reduce the inhibition and toxicity of the bioalcohols produced or by-products produced during pre-treatment, while enhancing the bioalcohol production. In the present study (chapter 5), evaluation of common conventional methods for the pretreatment of the mixed agro-waste, i.e. (˃45µm to <100µm) constituted by Citrus sinensis, Malus domestica peels, corn cobs from Zea mays and Quercus robur (oak) yard waste without a pre-rinsing step at a ratio of 1:1 at 25% (w/w) for each waste material, was undertaken, focusing on hot water pre treatment followed by dilute acid (H2SO4) pre-treatment. To further pretreat the mixed agro-waste residue, cellulases were used to further hydrolyse the pre-treated agro-waste in a single pot (batch) multi-reaction process. The TRS concentration of 0.12, 1.43 and 3.22 g/L was achieved with hot water, dilute acid and cellulases hydrolysis as sequential pretreatment steps, respectively, in a single pot multi-reaction system. Furthermore, a commercial strain was used to ascertain low (C1 to C3) and high carbon content (C4+) bioalcohol production under aerobic conditions. Multiple bioproducts were obtained within 48 to 72 h, including bioethanol and 1-Butanol, 3-methyl, which were major products for this study. However, undesirable bio-compounds such as phenolics, were detected post fermentation. Since multiple process units characterised by chemical usage and high energy intensivity have been utilized to overcome delignification and cellulolysis, a sustainable, environmental benign pretreatment process was proposed using N. mirabilis “monkey cup” fluids (extracts) to also reduce fermenter inhibitors from the delignification of mixed agrowaste; a process with minimal thermo physical chemical inputs for which a single pot multi-reaction system strategy was used. Nepenthes mirabilis extracts shown to have ligninolytic, cellulolytic and xylanolytic activities, were used as an enzyme cocktail to pretreat mixed agro-waste, subsequent to the furtherance of TRS production from the agro-waste, by further using cellulase for further hydrolysis. N. mirabilis pod extracts were determined to contained carboxylesterases (529.41±30.50 U/L), β-glucosidases (251.94±11.48 U/L) and xylanases (36.09±18.04 U/L), constituting an enzymatic cocktail with a significant potential for the reduction in total residual phenolic compounds (TRPCs). Furthermore, the results indicated that maximum concentration of TRS obtainable was 310±5.19 mg/L within 168 h, while the TRPCs were reduced from 6.25±0.18 to 4.26 ±0.09 mg/L, which was lower than that observed when conventional methods were used. Overall N. mirabilis extracts were demonstrated to have an ability to support biocatalytic processes for the conversion of agro-waste to produce fermentable TRS in a single unit facilitating multiple reactions with minimised interference with cellulase hydrolysis. Therefore, the digestive enzymes in N. mirabilis pods can be used in an integrated system for a second generation biorefinery.
Kang, Yuezhuang. "Computer-aided fixture design verification." Link to electronic thesis, 2002. http://www.wpi.edu/Pubs/ETD/Available/etd-0108102-163543.
Повний текст джерелаKeywords: Fixture stiffness matrix; Jacobian matrix; kinetic model; geometric model; fixture design verification; stability analysis; tolerance analysis; tolerance assignment. Includes bibliographical references (p. 92-97).
Schleicher, Simon [Verfasser], and Jan [Akademischer Betreuer] Knippers. "Bio-inspired compliant mechanisms for architectural design : transferring bending and folding principles of plant leaves to flexible kinetic structures / Simon Schleicher. Betreuer: Jan Knippers." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:93-opus-104850.
Повний текст джерелаKörner, Axel Hannes [Verfasser], and Jan [Akademischer Betreuer] Knippers. "Compliant folding : design and fabrication methodology for bio-inspired kinetic folding mechanisms utilized by distinct flexible hinge zones / Axel Hannes Körner ; Betreuer: Jan Knippers." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2021. http://d-nb.info/1239648731/34.
Повний текст джерелаAlexacou, Kyriaki-Melinda [Verfasser]. "Kinetic and X-ray crystallographic studies of glycogen phosphorylase : on the way to structure based drug design for diabetes type 2 / Kyriaki-Melinda Alexacou." Berlin : Freie Universität Berlin, 2010. http://d-nb.info/1025126777/34.
Повний текст джерелаNaifar, Slim [Verfasser], Olfa [Akademischer Betreuer] Kanoun, Olfa [Gutachter] Kanoun, Jörg [Gutachter] Himmel, and Tarak [Gutachter] Bouraoui. "Model Based Design of a Magnetoelectric Vibration Converter from Weak Kinetic Sources / Slim Naifar ; Gutachter: Olfa Kanoun, Jörg Himmel, Tarak Bouraoui ; Betreuer: Olfa Kanoun." Chemnitz : Universitätsverlag Chemnitz, 2019. http://d-nb.info/1215909225/34.
Повний текст джерелаSchleicher, Simon Verfasser], and Jan [Akademischer Betreuer] [Knippers. "Bio-inspired compliant mechanisms for architectural design : transferring bending and folding principles of plant leaves to flexible kinetic structures / Simon Schleicher. Betreuer: Jan Knippers." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2016. http://d-nb.info/1088404367/34.
Повний текст джерелаBenge, G. Gregory. "Cold model of a vibrated-bed microreactor capable of varying Peclet number at fixed weight hourly space velocity providing a tool for simulating an important feature of the reaction kinetic scene in large catalytic fluid beds." Diss., Virginia Tech, 1992. http://hdl.handle.net/10919/39083.
Повний текст джерелаPh. D.