Статті в журналах з теми "Isogenic cellular models"
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Paredes-Redondo, A., and Y. Y. Lin. "Developing novel human isogenic cellular models for Duchenne muscular dystrophy." Neuromuscular Disorders 27 (March 2017): S6. http://dx.doi.org/10.1016/s0960-8966(17)30234-1.
Zhang, Yuting, Emily Wilt, and Xin Lu. "Human Isogenic Cell Line Models for Neutrophils and Myeloid-Derived Suppressor Cells." International Journal of Molecular Sciences 21, no. 20 (October 18, 2020): 7709. http://dx.doi.org/10.3390/ijms21207709.
Benarroch, Louise, Julia Madsen-Østerbye, Mohamed Abdelhalim, Kamel Mamchaoui, Jessica Ohana, Anne Bigot, Vincent Mouly, Gisèle Bonne, Anne T. Bertrand, and Philippe Collas. "Cellular and Genomic Features of Muscle Differentiation from Isogenic Fibroblasts and Myoblasts." Cells 12, no. 15 (August 3, 2023): 1995. http://dx.doi.org/10.3390/cells12151995.
Pavan, Eleonora, Maximiliano Ormazabal, Paolo Peruzzo, Emilio Vaena, Paula Rozenfeld, and Andrea Dardis. "CRISPR/Cas9 Editing for Gaucher Disease Modelling." International Journal of Molecular Sciences 21, no. 9 (May 5, 2020): 3268. http://dx.doi.org/10.3390/ijms21093268.
Karwacka, Marianna, and Marta Olejniczak. "Advances in Modeling Polyglutamine Diseases Using Genome Editing Tools." Cells 11, no. 3 (February 2, 2022): 517. http://dx.doi.org/10.3390/cells11030517.
Klementieva, Natalia, Daria Goliusova, Julia Krupinova, Vladislav Yanvarev, Alexandra Panova, Natalia Mokrysheva, and Sergey L. Kiselev. "A Novel Isogenic Human Cell-Based System for MEN1 Syndrome Generated by CRISPR/Cas9 Genome Editing." International Journal of Molecular Sciences 22, no. 21 (November 8, 2021): 12054. http://dx.doi.org/10.3390/ijms222112054.
Boussaad, Ibrahim, Emily K. Dolezal, Fabiana Perna, Stephen D. Nimer, and Eirini P. Papapetrou. "IPS Cells From Del(7q)-MDS Patients Display Impaired Proliferation and Hematopoietic Commitment." Blood 120, no. 21 (November 16, 2012): 174. http://dx.doi.org/10.1182/blood.v120.21.174.174.
Muto, Valentina, Federica Benigni, Valentina Magliocca, Rossella Borghi, Elisabetta Flex, Valentina Pallottini, Alessandro Rosa, Claudia Compagnucci, and Marco Tartaglia. "CRISPR/Cas9 and piggyBac Transposon-Based Conversion of a Pathogenic Biallelic TBCD Variant in a Patient-Derived iPSC Line Allows Correction of PEBAT-Related Endophenotypes." International Journal of Molecular Sciences 24, no. 9 (April 28, 2023): 7988. http://dx.doi.org/10.3390/ijms24097988.
Li, Fenfang, Igor Cima, Jess Honganh Vo, Min-Han Tan, and Claus Dieter Ohl. "Single Cell Hydrodynamic Stretching and Microsieve Filtration Reveal Genetic, Phenotypic and Treatment-Related Links to Cellular Deformability." Micromachines 11, no. 5 (May 9, 2020): 486. http://dx.doi.org/10.3390/mi11050486.
Patel, Ronak, Shyanne Page, and Abraham Jacob Al-Ahmad. "Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality." Journal of Neurochemistry 142, no. 1 (May 14, 2017): 74–88. http://dx.doi.org/10.1111/jnc.14040.
Boussaad, Ibrahim, Andriana Kotini, Emily K. Dolezal, Stephen Nimer, and Eirini P. Papapetrou. "An iPSC-Based Model Of MDS For Phenotype-Driven Gene and Drug Discovery." Blood 122, no. 21 (November 15, 2013): 859. http://dx.doi.org/10.1182/blood.v122.21.859.859.
Haley, John A., Christian F. Ruiz, Emily D. Montal, Daifeng Wang, John D. Haley, and Geoffrey D. Girnun. "Decoupling of Nrf2 Expression Promotes Mesenchymal State Maintenance in Non-Small Cell Lung Cancer." Cancers 11, no. 10 (October 2, 2019): 1488. http://dx.doi.org/10.3390/cancers11101488.
Ghosal, Abhisek, Stefan Jellbauer, Rubina Kapadia, Manuela Raffatellu, and Hamid M. Said. "Salmonellainfection inhibits intestinal biotin transport: cellular and molecular mechanisms." American Journal of Physiology-Gastrointestinal and Liver Physiology 309, no. 2 (July 15, 2015): G123—G131. http://dx.doi.org/10.1152/ajpgi.00112.2015.
Ceballos-Garzon, Andres, Elvira Roman, Jesús Pla, Fabrice Pagniez, Daniela Amado, Carlos J. Alméciga-Díaz, Patrice Le Pape, and Claudia M. Parra-Giraldo. "CRISPR-Cas9 approach confirms Calcineurin-responsive zinc finger 1 (Crz1) transcription factor as a promising therapeutic target in echinocandin-resistant Candida glabrata." PLOS ONE 17, no. 3 (March 18, 2022): e0265777. http://dx.doi.org/10.1371/journal.pone.0265777.
Kálmán, Sára, Edit Hathy, and János M. Réthelyi. "A Dishful of a Troubled Mind: Induced Pluripotent Stem Cells in Psychiatric Research." Stem Cells International 2016 (2016): 1–21. http://dx.doi.org/10.1155/2016/7909176.
Wang, Wei, Tiansu Wang, Andriana G. Kotini, Camelia Iancu-Rubin, Ronald Hoffman, and Eirini P. Papapetrou. "Modeling Calreticulin-Mutant Myeloproliferative Neoplasms with Isogenic Induced Pluripotent Stem Cells." Blood 132, Supplement 1 (November 29, 2018): 4319. http://dx.doi.org/10.1182/blood-2018-99-111512.
Хамидуллина, А. И., Э. Р. Гандалипов, Я. Е. Абраменко, К. В. Чернов, Т. А. Кирюхина, А. В. Брутер, and В. В. Татарский. "Creation of A549 and MCF7 tumor sublines with knockout of TP53 using CRISPR/Cas9." Nauchno-prakticheskii zhurnal «Medicinskaia genetika 22, no. 11 (December 19, 2023): 27–34. http://dx.doi.org/10.25557/2073-7998.2023.11.27-34.
Charlebois, Daniel A., Kevin Hauser, Sylvia Marshall, and Gábor Balázsi. "Multiscale effects of heating and cooling on genes and gene networks." Proceedings of the National Academy of Sciences 115, no. 45 (October 19, 2018): E10797—E10806. http://dx.doi.org/10.1073/pnas.1810858115.
Lee, Hans C., Hua Wang, Bing-Zong Li, Zhiqiang Wang, Richard Julian Jones, Dongmin Gu, Sean O'Brien, Richard E. Davis, and Robert Z. Orlowski. "CX-5461, a Novel RNA Polymerase I Inhibitor, Is Active Against Wild-Type and Mutant p53 Myeloma Models." Blood 122, no. 21 (November 15, 2013): 4438. http://dx.doi.org/10.1182/blood.v122.21.4438.4438.
van Waardenburg, Robert C. A. M., Laurina A. de Jong, Foke van Delft, Maria A. J. van Eijndhoven, Melanie Bohlander, Mary-Ann Bjornsti, Jaap Brouwer, and Jan H. M. Schellens. "Homologous recombination is a highly conserved determinant of the synergistic cytotoxicity between cisplatin and DNA topoisomerase I poisons." Molecular Cancer Therapeutics 3, no. 4 (April 1, 2004): 393–402. http://dx.doi.org/10.1158/1535-7163.393.3.4.
Rakotomalala, Andria, Paul Lewandowski, Quentin Bailleul, Clara Savary, Mélanie Arcicasa, Christine Bal, Maud Hamadou, et al. "Abstract 1671: Engineering new cellular models to decipher H3.3K27M mutation role in DIPGs' resistance to therapies." Cancer Research 82, no. 12_Supplement (June 15, 2022): 1671. http://dx.doi.org/10.1158/1538-7445.am2022-1671.
De Souza, Cristabelle, Jill A. Madden, Dennis Minn, Vigneshwari Easwar Kumar, Dennis J. Montoya, Roshni Nambiar, Zheng Zhu, et al. "The P72R Polymorphism in R248Q/W p53 Mutants Modifies the Mutant Effect on Epithelial to Mesenchymal Transition Phenotype and Cell Invasion via CXCL1 Expression." International Journal of Molecular Sciences 21, no. 21 (October 28, 2020): 8025. http://dx.doi.org/10.3390/ijms21218025.
Jungles, Kassidy M., Andrea M. Pesch, Nicole Hirsh, Anna R. Michmerhuizen, Kari Wilder-Romans, Benjamin C. Chandler, Meilan Liu, et al. "Abstract 216: Expression of DNA damage response proteins modifies the efficacy of CDK4/6 inhibitor-mediated radiosensitization in breast cancer models." Cancer Research 82, no. 12_Supplement (June 15, 2022): 216. http://dx.doi.org/10.1158/1538-7445.am2022-216.
Chakrabarty, Anindita, Sreeraj Surendran, Neil E. Bhola, Vishnu S. Mishra, Tasaduq Hussain Wani, Khemraj S. Baghel, Carlos L. Arteaga, Rohini Garg, and Goutam Chowdhury. "The H1047R PIK3CA oncogene induces a senescence-like state, pleiotropy and acute HSP90 dependency in HER2+ mammary epithelial cells." Carcinogenesis 40, no. 10 (June 18, 2019): 1179–90. http://dx.doi.org/10.1093/carcin/bgz118.
Costamagna, Gianluca, Giacomo Pietro Comi, and Stefania Corti. "Advancing Drug Discovery for Neurological Disorders Using iPSC-Derived Neural Organoids." International Journal of Molecular Sciences 22, no. 5 (March 6, 2021): 2659. http://dx.doi.org/10.3390/ijms22052659.
Wenzl, Kerstin, Michelle Manske, Paola Martinez, Stephen Ansell, James R. Cerhan, and Anne J. Novak. "Isogenic Loss of TNFAIP3 in Waldenstrom Macroglobulinemia Enhances MYD88L265P-Driven Signaling." Blood 128, no. 22 (December 2, 2016): 4100. http://dx.doi.org/10.1182/blood.v128.22.4100.4100.
Ferri-Borgogno, Sammy, Sugata Barui, Amberly M. McGee, Tamara Griffiths, Pankaj K. Singh, Cortt G. Piett, Bidyut Ghosh, et al. "Paradoxical Role of AT-rich Interactive Domain 1A in Restraining Pancreatic Carcinogenesis." Cancers 12, no. 9 (September 21, 2020): 2695. http://dx.doi.org/10.3390/cancers12092695.
Hollywood, Jennifer A., Aneta Przepiorski, Randall F. D’Souza, Sreevalsan Sreebhavan, Ernst J. Wolvetang, Patrick T. Harrison, Alan J. Davidson, and Teresa M. Holm. "Use of Human Induced Pluripotent Stem Cells and Kidney Organoids To Develop a Cysteamine/mTOR Inhibition Combination Therapy for Cystinosis." Journal of the American Society of Nephrology 31, no. 5 (March 20, 2020): 962–82. http://dx.doi.org/10.1681/asn.2019070712.
Jung, Moonjung, Stefan Cordes, Jizhong Zou, Shiqin J. Yu, Xavi Guitart, So Gun Hong, Vinh Dang, et al. "GATA2 deficiency and human hematopoietic development modeled using induced pluripotent stem cells." Blood Advances 2, no. 23 (December 11, 2018): 3553–65. http://dx.doi.org/10.1182/bloodadvances.2018017137.
Sidhu, Ishnoor, Sonali P. Barwe, Raju K. Pillai, and Anilkumar Gopalakrishnapillai. "Harnessing the Power of Induced Pluripotent Stem Cells and Gene Editing Technology: Therapeutic Implications in Hematological Malignancies." Cells 10, no. 10 (October 9, 2021): 2698. http://dx.doi.org/10.3390/cells10102698.
Malladi, Srinivas. "Abstract P1-06-08: Metabolic diversity determines metastatic fitness of breast cancer brain-tropic cells." Cancer Research 82, no. 4_Supplement (February 15, 2022): P1–06–08—P1–06–08. http://dx.doi.org/10.1158/1538-7445.sabcs21-p1-06-08.
Grantcharova, Nina, Verena Peters, Claudia Monteiro, Katherina Zakikhany, and Ute Römling. "Bistable Expression of CsgD in Biofilm Development of Salmonella enterica Serovar Typhimurium." Journal of Bacteriology 192, no. 2 (November 6, 2009): 456–66. http://dx.doi.org/10.1128/jb.01826-08.
Gerritsen, Jacqueline S., Joseph S. Faraguna, Rudy Bonavia, Frank B. Furnari, and Forest M. White. "Predictive data-driven modeling of C-terminal tyrosine function in the EGFR signaling network." Life Science Alliance 6, no. 8 (May 11, 2023): e202201466. http://dx.doi.org/10.26508/lsa.202201466.
Kotini, Andriana, Jeffrey J. Delrow, Timothy A. Graubert, Stephen Nimer, and Eirini P. Papapetrou. "Functional Dissection of Chromosome 7q Loss and Haploinsufficient Gene Discovery Using iPSC Models of MDS." Blood 124, no. 21 (December 6, 2014): 524. http://dx.doi.org/10.1182/blood.v124.21.524.524.
Lemaire, Sandrine, Klaudia Kosowska-Shick, Peter C. Appelbaum, Gunther Verween, Paul M. Tulkens, and Françoise Van Bambeke. "Cellular Pharmacodynamics of the Novel Biaryloxazolidinone Radezolid: Studies with Infected Phagocytic and Nonphagocytic cells, Using Staphylococcus aureus, Staphylococcus epidermidis, Listeria monocytogenes, and Legionella pneumophila." Antimicrobial Agents and Chemotherapy 54, no. 6 (April 12, 2010): 2549–59. http://dx.doi.org/10.1128/aac.01724-09.
Javier, Rodrigo, and Craig Horbinski. "TAMI-48. THE KETOGENIC DIET IS INEFFECTIVE IN PRECLINICAL MODELS OF IDH1 WILD-TYPE AND IDH1 MUTANT GLIOMA." Neuro-Oncology 23, Supplement_6 (November 2, 2021): vi208. http://dx.doi.org/10.1093/neuonc/noab196.831.
Frank, Karen M., Tong Zhou, Liliana Moreno-Vinasco, Brian Hollett, Joe G. N. Garcia, and Juliane Bubeck Wardenburg. "Host Response Signature to Staphylococcus aureus Alpha-Hemolysin Implicates Pulmonary Th17 Response." Infection and Immunity 80, no. 9 (June 25, 2012): 3161–69. http://dx.doi.org/10.1128/iai.00191-12.
Lara-Chacón, Bárbara, Sandra L. Guerrero-Rodríguez, Karla J. Ramírez-Hernández, Angélica Yamilett Robledo-Rivera, Marco Antonio Velasco Velazquez, Roberto Sánchez-Olea, and Mónica Raquel Calera. "Gpn3 Is Essential for Cell Proliferation of Breast Cancer Cells Independent of Their Malignancy Degree." Technology in Cancer Research & Treatment 18 (January 1, 2019): 153303381987082. http://dx.doi.org/10.1177/1533033819870823.
My, Ilaria, and Elisa Di Pasquale. "Genetic Cardiomyopathies: The Lesson Learned from hiPSCs." Journal of Clinical Medicine 10, no. 5 (March 9, 2021): 1149. http://dx.doi.org/10.3390/jcm10051149.
Manceau, Line, Julien Richard Albert, Pier-Luigi Lollini, Maxim V. C. Greenberg, Pascale Gilardi-Hebenstreit, and Vanessa Ribes. "Divergent transcriptional and transforming properties of PAX3-FOXO1 and PAX7-FOXO1 paralogs." PLOS Genetics 18, no. 5 (May 23, 2022): e1009782. http://dx.doi.org/10.1371/journal.pgen.1009782.
Kargaran, Parisa K., Jared M. Evans, Sara E. Bodbin, James G. W. Smith, Timothy J. Nelson, Chris Denning, and Diogo Mosqueira. "Mitochondrial DNA: Hotspot for Potential Gene Modifiers Regulating Hypertrophic Cardiomyopathy." Journal of Clinical Medicine 9, no. 8 (July 23, 2020): 2349. http://dx.doi.org/10.3390/jcm9082349.
Ntai, Ioanna, Luca Fornelli, Caroline J. DeHart, Josiah E. Hutton, Peter F. Doubleday, Richard D. LeDuc, Alexandra J. van Nispen, et al. "Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk." Proceedings of the National Academy of Sciences 115, no. 16 (April 2, 2018): 4140–45. http://dx.doi.org/10.1073/pnas.1716122115.
Jacobs, Keith M., Sandeep Misri, Barbara Meyer, Suyash Raj, Cheri L. Zobel, Barry P. Sleckman, Dennis E. Hallahan, and Girdhar G. Sharma. "Unique epigenetic influence of H2AX phosphorylation and H3K56 acetylation on normal stem cell radioresponses." Molecular Biology of the Cell 27, no. 8 (April 15, 2016): 1332–45. http://dx.doi.org/10.1091/mbc.e16-01-0017.
Rosenthal, Dean S., Elijah Finn, Devin Teehan, Nusrat Islam, Veerupaxagouda Patil, Bonnie Carney, Scott S. Rosenthal, Lucia Dussan, Cynthia M. Simbulan-Rosenthal, and Peter Sykora. "Abstract B035: Developing the UValidate platform to measure DNA damage and repair capacity in isogenic donor-derived skin keratinocytes, fibroblasts and melanocyte cell-lines with different Fitzpatrick phototypes." Cancer Research 84, no. 1_Supplement (January 9, 2024): B035. http://dx.doi.org/10.1158/1538-7445.dnarepair24-b035.
Vötsch, Désirée, Maren Willenborg, Walter M. R. Oelemann, Graham Brogden, and Peter Valentin-Weigand. "Membrane Binding, Cellular Cholesterol Content and Resealing Capacity Contribute to Epithelial Cell Damage Induced by Suilysin of Streptococcus suis." Pathogens 9, no. 1 (December 30, 2019): 33. http://dx.doi.org/10.3390/pathogens9010033.
Meng, Qingyuan, Xiao Ding, Xiaosong Liu, Hailong Wang, Ling Wang, Junwen Qiao, Hua Cao, et al. "Abstract 503: ISM3412, a novel and selective MAT2A inhibitor for the treatment of cancer." Cancer Research 83, no. 7_Supplement (April 4, 2023): 503. http://dx.doi.org/10.1158/1538-7445.am2023-503.
Jenkins, Samir V., Shruti Shah, Azemat Jamshidi-Parsian, Amir Mortazavi, Gunnar Boysen, Kieng B. Vang, Robert J. Griffin, Narasimhan Rajaram, and Ruud P. Dings. "Abstract 1088: Acquired radiation resistance induces thiol-dependent cisplatin cross-resistance." Cancer Research 83, no. 7_Supplement (April 4, 2023): 1088. http://dx.doi.org/10.1158/1538-7445.am2023-1088.
Tawil, Nadim, Rayhaan Bassawon, Brian Meehan, Laura Montermini, Dongsic Choi, Ali Nehme, Hamed Najafabadi, et al. "OPTC-5. Molecular signatures of podoplanin expressing glioblastoma cell subsets with putative role in cancer associated thrombosis and microthrombosis." Neuro-Oncology Advances 3, Supplement_2 (July 1, 2021): ii7. http://dx.doi.org/10.1093/noajnl/vdab070.026.
Maurissen, Thomas L., Masahide Kawatou, Víctor López-Dávila, Kenji Minatoya, Jun K. Yamashita, and Knut Woltjen. "Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues." Scientific Reports 14, no. 1 (January 31, 2024). http://dx.doi.org/10.1038/s41598-024-52871-1.
Lebedeva, Irina V., Michelle V. Wagner, Sunil Sahdeo, Yi-Fan Lu, Anuli Anyanwu-Ofili, Matthew B. Harms, Jehangir S. Wadia, Gunaretnam Rajagopal, Michael J. Boland, and David B. Goldstein. "Precision genetic cellular models identify therapies protective against ER stress." Cell Death & Disease 12, no. 8 (August 2021). http://dx.doi.org/10.1038/s41419-021-04045-4.