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1

Yu, Ting, Ligui Wu, Ling Yuan, Robert Dawson, Rongmei Li, Zhenzhu Qiu, Xiancui Wu, et al. "The diagnostic value of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients: A retrospective multicenter study." Journal of Vascular Access 20, no. 6 (March 28, 2019): 636–45. http://dx.doi.org/10.1177/1129729819838136.

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Purpose: To evaluate the feasibility and accuracy of intracavitary electrocardiogram for verifying tip position of peripherally inserted central catheters in cancer patients during follow-up period. Methods: From March 2015 to October 2015, 126 patients involved in eight hospitals who underwent peripherally inserted central catheter placement received intracavitary electrocardiogram and chest X-ray to verify position of the catheter tip during follow-up period. Their intracavitary electrocardiogram was compared with surface electrocardiogram to judge catheter tip landing zone in one of three different anatomical zones. The amplitude of intracavitary electrocardiogram P wave and the ratio of intracavitary electrocardiogram P wave/surface electrocardiogram P wave were measured and showed correlation with catheter tip position confirmed by chest X-ray. Based on chest X-ray principle, all the cases were assigned into three intracavitary electrocardiogram groups to explore the optimal cut-off values for intracavitary electrocardiogram P wave and intracavitary electrocardiogram P wave/surface electrocardiogram P wave by analyzing the receiver operating characteristic. Results: No technique-related complications or adverse events occurred in this study. The matching rate between intracavitary electrocardiogram and chest X-ray method was 93.7%. The optimal cut-off values for intracavitary electrocardiogram P wave were set from 3.15 to 3.75 mV, and intracavitary electrocardiogram P wave/surface electrocardiogram P wave from 1.65 to 3.25. Conclusions: It is demonstrated in this retrospective multicenter study that the intracavitary electrocardiogram method for verifying tip position of peripherally inserted central catheter during follow-up period is feasible and accurate in all adult patients with cancer.
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2

Markman, Maurie, and Franco M. Muggia. "Intracavitary chemotherapy." Critical Reviews in Oncology/Hematology 3, no. 3 (January 1985): 205–33. http://dx.doi.org/10.1016/s1040-8428(85)80027-5.

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3

Markman, Maurie. "Intracavitary chemotherapy." Current Problems in Cancer 10, no. 8 (August 1986): 401–37. http://dx.doi.org/10.1016/s0147-0272(86)80014-9.

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4

Marchiori, Edson, Bruno Hochhegger, and Gláucia Zanetti. "Intracavitary nodule." Jornal Brasileiro de Pneumologia 42, no. 5 (October 2016): 309. http://dx.doi.org/10.1590/s1806-37562016000000223.

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5

Lushnikova, P. A., E. S. Sukhikh, P. V. Izhevsky, Ya N. Sutygina, M. A. Tatarchenko, and I. B. Pyzhova. "Modern Techniques for Cervical Cancer Radiotherapy." Creative surgery and oncology 11, no. 1 (April 13, 2021): 58–67. http://dx.doi.org/10.24060/2076-3093-2021-11-1-58-67.

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Cervical cancer is a socially significant illness often impacting women of reproductive and working age. The patients’ young age and social activity warrant the development of effective and safe therapies.The past decades have witnessed the novel radiation techniques to contain cervical cancer: 3DCRT-3D, IMRT, and VMAT, adaptive radiotherapy, CT/MRI-guided intracavitary radiation, combined interstitial and intracavitary radiation, abandoning intracavitary intervention for external beam delivery with sequential or concurrent cervical dose escalation, under brachytherapy unfeasible.Modern equipment and treatment planning systems allow a high dose delivery to the tumour and intracavitary treatment with visual control of the target and organs at risk. Combining of intracavitary and interstitial radiotherapy enables a better dose coverage of the target at a minimal radiation impact on organs at risk.Phasing-out of intracavitary for external radiotherapy may enable a cancericide dose delivery to the tumour under intractable intracavitary treatment.The major goal of technic novelties is the establishment of personalised radiotherapy for improving treatment outcomes and reducing the incidence and/or severity of radiation side effects. The article overviews the radiotherapy techniques for cervical cancer treatment and routes of their development.
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6

Stefanovic, Ivan, Nebojsa Stojanovic, Dragan Stojanov, and Dragan Dimov. "Octreotide in the therapy of recurrent medulloblastomas." Archive of Oncology 14, no. 1-2 (2006): 26–29. http://dx.doi.org/10.2298/aoo0602026s.

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BACKGROUND: Recurrence of medulloblastoma appears after 30% to 40% of the surgeries. Different from primary medulloblastoma, in which five-year survival rate is 50%, the survival time of relapses much shorter and only 20% of the patients manage to survive a year. There is a logical need for additional methods of treatment of recurrent medulloblastomas. The aim of the study is to determine the effects of intracavitary and long-term subcutaneous application of Sandostatin (octreotide) on the recurrent medulloblastomas. METHODS: Fourteen children aged 4 to 9 years, in which, despite of craniospinal irradiation and chemotherapy came to a recurrence of medulloblastoma during the first 6 months after the surgery, were treated subcutaneously with Sandostatin (octreotide) in a longer period of time. Cerebellar medulloblastomas with a diameter bigger than 20 mm and spinal over 10 mm were removed operatively and octreotide with Beriplast was applied intracavitary. RESULTS: Magnetic resonance of cranioaxis shows that the application of octreotide has caused the disappearance of spinal drop metastases in all 7 patients and the cerebellar metastases smaller than 5 mm in all 4 patients. Subcutaneous application of octreotide combined with intracavitary expresses an antitumoral effect in 2/3 of the relapses. The application of octreotide results with a transformation of Chang's stage M0 into M1 in 71.43% of the patients. CONCLUSION: In the case of in loco or metastatic recurrence of medulloblastomas, intracavitarily and subcutaneously applied octreotide results with a regression of the tumor in a 3 year time within 2/3 of the treated patients.
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7

Capasso, Antonella, Rossella Mastroianni, Annalisa Passariello, Marta Palma, Francesco Messina, Antonella Ansalone, Italo Bernardo, et al. "The intracavitary electrocardiography method for positioning the tip of epicutaneous cava catheter in neonates: Pilot study." Journal of Vascular Access 19, no. 6 (March 18, 2018): 542–47. http://dx.doi.org/10.1177/1129729818761292.

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Purpose: The neonatologists of Sant’Anna and San Sebastiano Hospital of Caserta have carried out a pilot study investigating the safety, feasibility, and accuracy of intracavitary electrocardiography for neonatal epicutaneous cava catheter tip positioning. Patients and methods: We enrolled 39 neonates (1–28 days of postnatal age or correct age lower than 41 weeks) requiring epicutaneous cava catheter in the district of superior vena cava (head–neck or upper limbs). Intracavitary electrocardiography was applicable in 38 neonates. Results: No significant complications related to intracavitary electrocardiography occurred in the studied neonates. The increase in P wave on intracavitary electrocardiography was detected in 30 cases. Of the remaining eight cases, six malpositioned catheters tipped out of cavoatrial junction–target zone (chest x-ray and echocardiographical control) and two were false negative (tip located in target zone). The match between intracavitary electrocardiography and x-ray was observed in 29/38 cases, and the same ratio between intracavitary electrocardiography and echocardiography was detected. Conclusion: We conclude that the intracavitary electrocardiography method is safe and accurate in neonates as demonstrated in pediatric and adult patients. The applicability of the method is 97% and its feasibility is 79%. The overall accuracy is 76% but it rises to 97% if “peak” P wave is detected.
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8

Liu, Guang, Wenbo Hou, Chao Zhou, Yuxia Yin, Shoutao Lu, Cuihai Duan, Maoquan Li, Egon Steen Toft, and Haijun Zhang. "Meta-analysis of intracavitary electrocardiogram guidance for peripherally inserted central catheter placement." Journal of Vascular Access 20, no. 6 (March 6, 2019): 577–82. http://dx.doi.org/10.1177/1129729819826028.

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Background:Recently, intracavitary electrocardiogram technology has been applied to peripherally inserted central catheter placement and demonstrates many potential advantages. However, the tip positioning accuracy of intracavitary electrocardiogram technology compared to conventional X-ray method is unknown.Objective:We did a meta-analysis to compare the tip positioning accuracy between intracavitary electrocardiogram technology and conventional X-ray method.Data sources:We searched several databases, including Cochrane Library, PubMed, Web of science, and Embase. Additional studies were identified through hand searches of bibliographies and Internet searches. All human studies published in full text, abstract, or poster form were eligible for inclusion. Search terms included peripherally inserted central catheter, PICC, intracavitary electrocardiogram, IC-ECG, EKG, ECG, and catheter tip location.Study eligibility criteria:Only randomized controlled trials of using intracavitary electrocardiogram technology versus X-ray method for peripherally inserted central catheter placement were included. All studies included adult patients aged at least 18 years.Study appraisal and synthesis methods:Independent extraction of articles by two authors using predefined data fields, including study quality indicators. Of the 178 citations identified, 5 studies that included 1672 patients met the eligibility criteria. It was found that statistical heterogeneity existed among the various studies (I2 = 16%, p < 0.00001); therefore, the fixed effect model was used in the meta-analysis (p < 0.05). The meta-analysis compared the tip positioning accuracy between intracavitary electrocardiogram technology and X-ray method and showed that intracavitary electrocardiogram technology had a better positioning accuracy (odds ratio: 2.88, 95% confidence interval: 2.15–3.87, p < 0.0001).Limitations:Only five randomized trial met inclusion criteria, and the lack of an incomplete search led to the publication bias seen in these results.Conclusion:The intracavitary electrocardiogram method had a more favorable positioning accuracy versus traditional X-ray method for peripherally inserted central catheter placement in adult patients. The intracavitary electrocardiogram can be a promising technique to guide tip positioning of peripherally inserted central catheter.
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9

Monard, Céline, Mathilde Lefèvre, Fabien Subtil, Vincent Piriou, and Jean-Stephane David. "Peripherally inserted central catheter with intracavitary electrocardiogram guidance: Malposition risk factors and indications for post-procedural control." Journal of Vascular Access 20, no. 2 (June 25, 2018): 128–33. http://dx.doi.org/10.1177/1129729818781266.

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Objectives: To confirm the feasibility of intracavitary electrocardiogram guidance to verify tip’s position during insertion of peripherally inserted central catheter and to identify clinical factors or intracavitary electrocardiogram patterns associated with aberrant tip’s position. Methods: A prospective study was conducted in our university hospital after authorization of the ethics committee. All patients addressed for peripherally inserted central catheter insertion were included and received the insertion using intracavitary electrocardiogram and electromagnetic guidance. Side of insertion and three electrocardiogram factors were collected: visualization of P-wave at baseline (sinusal rhythm), acquisition of the maximal P-wave and the negative deflection. All patients had a systematic post-procedural chest X-ray. One of the investigators assessed all chest X-ray, blinded to the results of intracavitary electrocardiogram, and confirmed whether the tip’s position on chest X-ray matched with the intracavitary electrocardiogram information or if the tip was malpositioned on chest X-ray (mismatch with intracavitary electrocardiogram or aberrant position). Factors associated with malposition were described. Results: From January 2015 to April 2015, 330 patients were eligible, 5 had an uninterpretable chest X-ray, and 14 were non-sinusal at baseline. Our main analysis population included 311 patients. We observed a mismatch between intracavitary electrocardiogram and chest X-ray estimate of the tip’s position in 3 cases (1%) and an aberrant tip’s position occurred in 3 cases (1%). Incidence of malposition was higher in the group of patients with non-sinusal rhythm (14%) and when the catheter was inserted on the left side (7%). Conclusion: This study confirmed the feasibility of intracavitary electrocardiogram for peripherally inserted central catheter positioning and the limits of chest X-ray. Insertion on left side may represent risk factor for aberrant position but our study lacked power to establish a statistical link.
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10

Mastroianni, Rossella, Antonella Capasso, and Gaetano Ausanio. "The intracavitary electrocardiography method for tip location of jugular internal vein access device in infants of less than 5 kg: A pilot study." Journal of Vascular Access 19, no. 6 (April 13, 2018): 639–43. http://dx.doi.org/10.1177/1129729818769028.

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Purpose: This is a prospective observational study conducted by neonatologists in neonatal intensive care unit from Sant’Anna and San Sebastiano Hospital, Caserta, Italy. The objective of the study is to verify the feasibility of intracavitary electrocardiography method for tip location of central venous access device in infants of less than 5 kg and evaluate the accuracy of the method in comparison with post-procedural echocardiographical verification of the tip position. Patients and methods: We enrolled 27 patients weighted between 0.660 and 5 kg, requiring central vascular access. Ultrasound-guided jugular internal vein access was used and after cannulation, we applied the intracavitary electrocardiography for tip location as well as post-procedural echocardiography. Results: No significant complication related to intracavitary electrocardiography occurred in the studied infants. The increase in P wave on intracavitary electrocardiography was detected in all cases (27/27). In only one case (false positive), the catheter had the tip out of cavoatrial junction–target zone (to post-procedural echocardiography). Conclusion: The intracavitary electrocardiography method for tip location of central venous access device is safe and accurate in infants, as demonstrated by post-procedural comparative echocardiographic controls. As an alternative to echocardiography, not always achievable, the diffusion of intracavitary electrocardiography method could reduce X-ray exposition and complications of a malpositioned tip.
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11

Green, George E. "Intracavitary Coronary Arteries." Annals of Thoracic Surgery 40, no. 1 (July 1985): 99–100. http://dx.doi.org/10.1016/s0003-4975(10)61188-5.

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12

Ochsner, John L., and Noel L. Mills. "Intracavitary Coronary Arteries." Annals of Thoracic Surgery 40, no. 1 (July 1985): 100. http://dx.doi.org/10.1016/s0003-4975(10)61189-7.

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13

Green, George E. "Intracavitary Coronary Arteries." Annals of Thoracic Surgery 41, no. 4 (April 1986): 463. http://dx.doi.org/10.1016/s0003-4975(10)62716-6.

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14

Parsonnet, Victor. "Intracavitary Coronary Arteries." Annals of Thoracic Surgery 40, no. 2 (August 1985): 206. http://dx.doi.org/10.1016/s0003-4975(10)60026-4.

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15

Ochsner, John L., and Noel L. Mills. "Intracavitary Coronary Arteries." Annals of Thoracic Surgery 40, no. 2 (August 1985): 206. http://dx.doi.org/10.1016/s0003-4975(10)60027-6.

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16

Leung, To-Wai, Stewart Y. Tung, Victy Y. W. Wong, Wing-Kin Sze, Collin M. M. Lui, Frank C. S. Wong, Ann-Shing Lee, and Sai-Ki O. "Nasopharyngeal intracavitary brachytherapy." Cancer 104, no. 8 (2005): 1648–55. http://dx.doi.org/10.1002/cncr.21371.

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17

Hossain, Rydhwana, Lydia Chelala, Sagar B. Amin, Peter J. Bergquist, Jenanan Vairavamurthy, Jean Jeudy, and Charles S. White. "Intracavitary Coronary Artery." Journal of Thoracic Imaging 34, no. 5 (September 2019): W121—W124. http://dx.doi.org/10.1097/rti.0000000000000418.

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18

Gorginzadeh, Mansoureh, Kobra Tahermanesh, Soheil Hanjani, Azadeh Khorshidizadeh, Leila Allahqoli, Alireza Sadeghipour, and Abbas Fazel Anvari-Yazdi. "Uterine intracavitary angioleiomyoma." Journal of Obstetrics and Gynaecology 40, no. 8 (February 18, 2020): 1186–88. http://dx.doi.org/10.1080/01443615.2019.1705775.

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19

Guven, M. A., T. Bese, and F. Demirkiran. "Comparison of hydrosonography and transvaginal ultrasonography in the detection of intracavitary pathologies in women with abnormal uterine bleeding." International Journal of Gynecologic Cancer 14, no. 1 (January 2004): 57–63. http://dx.doi.org/10.1136/ijgc-00009577-200401000-00007.

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BackgroundThe aim of the study was to compare the accuracy of hydrosonography with that of transvaginal ultrasonography in detection of intracavitary pathologies in patients with history of abnormal uterine bleeding.Study designProspective, randomized, and unblinded study.Material and methodsA total of 197 women (n = 130 premenopausal and n = 67 postmenopausal) aged between 23 and 71 years (mean age 45.7 ± 8.9) presenting with a history of abnormal uterine bleeding were included into the study. Hydrosonography was carried out by experienced gynecologists, on the same setting in an outpatient clinic immediately after the performance of transvaginal sonography. The finally obtained surgical-pathologic findings were compared with the results obtained from transvaginal sonography and hydrosonography. Sensitivity, specificity, positive, and negative predictive values were calculated for each procedure.ResultsThe surgical-pathologic examination confirmed normal physiologic endometrium in 50 (48%) of 104 women who were said to have normal endometrium on transvaginal sonography. Seventy (75%) of 93 women diagnosed of intracavitary pathologies on transvaginal sonography were confirmed by surgical-pathologic findings. The sensitivity, specificity, positive predictive value, and negative predictive value of transvaginal sonography in the detection of intracavitary pathology were 56, 68, 75, and 48%, respectively. Surgical-pathologic results revealed intracavitary pathologies in 23 (30%) of 76 women who were said to have normal endometrium on hydrosonography. Among 121 women diagnosed of intracavitary pathologies on hydrosonography, 101 (81%) women were confirmed after histological evaluation of the surgical specimens. The sensitivity, specificity, positive predictive value, and negative predictive value of hydrosonography in the detection of intracavitary pathology were 81, 73, 83, and 70%, respectively. Sensitivity and negative predictive value were significantly higher with hydrosonography. There were five cases of endometrial malignancy in which one of the case of malignancy was on polyp and two cases of endometrial hyperplasia with atypia which were not stated on sonographic results.ConclusionHydrosonography is more accurate than transvaginal ultrasography in the detection of intracavitary pathologies in women with abnormal uterine bleeding.
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20

Lissoni, Paolo, Sandro Barni, Antonio Ardizzoia, Franco Paolorossi, Elisabetta Tisi, Sergio Crispino, and Gabriele Tancini. "Intracavitary Administration of Interleukin-2 as Palliative Therapy for Neoplastic Effusions." Tumori Journal 78, no. 2 (April 1992): 118–20. http://dx.doi.org/10.1177/030089169207800211.

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Cytokines have recently appeared to be effective in the palliative therapy of neoplastic effusions. The present study was carried out to evaluate the efficacy and the tolerability of an intracavitary injection of IL-2 in patients with neoplastic effusion due to solid tumors. The study included 14 patients with cytologically positive effusion (pleura, 11; peritoneum, 2; pericardium, 1). Tumor histotypes were: mesothelioma, 5; non-small cell lung cancer, 3; breast cancer, 2; ovarian cancer, 2; cervix carcinoma, 1; unknown primary tumor, 1. The efficacy was evaluated according to the criteria of Paladine et al. (Cancer 38: 1903, 1976). An objective response was achieved in 10/14 (71 %) patients (4 CR, 6 PR), with a median duration of 4 months (range, 2-8). No important toxicity was seen. This preliminary study showed that low dose IL-2 given intracavitarily is an effective and well-tolerated therapy in patients with neoplastic effusions.
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21

Yin, Yu-Xia, Wei Gao, Xu-Ying Li, Wei Lu, Qian-Hong Deng, Cui-Yun Zhao, Xue-Rong Liu, et al. "Insertion of peripherally inserted central catheters with intracavitary electrocardiogram guidance: A randomized multicenter study in China." Journal of Vascular Access 20, no. 5 (December 31, 2018): 524–29. http://dx.doi.org/10.1177/1129729818819732.

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Introduction: Ultrasound-guided venipuncture and tip location by intracavitary electrocardiogram have many advantages during the insertion of peripherally inserted central catheters, both in terms of safety and cost-effectiveness. Recently, a new tip-conductive peripherally inserted central catheters and new Doppler ultrasound device integrated with intracavitary electrocardiogram have been introduced into clinical practice in China. A randomized multicenter study (clinical trial no. NCT03230357) was performed to verify the feasibility and accuracy of intracavitary electrocardiogram, as performed with this new peripherally inserted central catheters and device. Methods: Our study enrolled a total of 2250 adult patients in 10 different Chinese hospitals. The patients were randomly assigned to either the study group (intracavitary electrocardiogram) or the control group (anatomical landmark guidance) in a 2:1 allocation. Ultrasound was used in both groups for venipuncture and tip navigation. All patients underwent chest X-ray after the procedure to verify the position of the catheter tip. Results: No insertion-related complications were reported in either group. In the study group, first-attempt successful tip location was 91.7% (95% confidence interval: 90.3%–93.1%), significantly higher than 78.9% (95% confidence interval: 76.0%–81.9%) observed in the control group (p < 0.001). As evaluated by post-procedural chest X-ray, tip location in the study group had a sensitivity of 99.3% (95% confidence interval: 98.8%–99.7%), significantly higher than 86.8% (95% confidence interval: 84.4%–89.2%) observed in the anatomical landmark group (p < 0.001). Conclusion: These results indicated that during peripherally inserted central catheters insertion in adult patients, tip location with intracavitary electrocardiogram guidance, as carried out by a new tip-conductive peripherally inserted central catheters and intracavitary electrocardiogram integrated ultrasound device, was more effective and more accurate than tip location using anatomical landmarks.
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22

Verschraegen, Claire F. "Intracavitary therapies for mesothelioma." Current Treatment Options in Oncology 2, no. 5 (September 2001): 385–94. http://dx.doi.org/10.1007/s11864-001-0043-3.

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23

Abid, A. "Intracavitary cardiac hydatid cyst." Cardiovascular Surgery 11, no. 6 (December 2003): 521–25. http://dx.doi.org/10.1016/s0967-2109(03)00116-9.

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24

Andrade, Jason G., Brett G. Heilbron, and Jonathon A. Leipsic. "Intracavitary right coronary artery." Canadian Journal of Cardiology 26, no. 6 (June 2010): e211-e212. http://dx.doi.org/10.1016/s0828-282x(10)70403-7.

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25

Hetz, Walter. "Intracavitary ultrasound scanner means." Journal of the Acoustical Society of America 89, no. 5 (May 1991): 2488. http://dx.doi.org/10.1121/1.400875.

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26

Alsumrain, Mohammad, Enis Alberaqdar, Arianne Bennett-Vernner, Alan Klukowicz, and Richard Miller. "Intracavitary and Endobronchial Tuberculosis." Scientific World JOURNAL 11 (2011): 130–32. http://dx.doi.org/10.1100/tsw.2011.18.

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27

Marrone, Gianluca, Francesca Crino, Giuseppe Mamone, Giovanni Gentile, and Settimo Caruso. "Intracavitary right coronary artery." European Heart Journal - Cardiovascular Imaging 21, no. 8 (April 14, 2020): 935. http://dx.doi.org/10.1093/ehjci/jeaa049.

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28

Severo, L. C., A. Kaemmerer, J. J. Camargo, and N. S. Porto. "Actinomycotic intracavitary lung colonization." Mycopathologia 108, no. 1 (October 1989): 1–4. http://dx.doi.org/10.1007/bf00436776.

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29

Markman, Maurie. "Review: Cytotoxic Intracavitary Chemotherapy." American Journal of the Medical Sciences 291, no. 3 (March 1986): 175–79. http://dx.doi.org/10.1097/00000441-198603000-00006.

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30

Abid, A., S. Ben Omrane, K. Kaouel, A. Marghli, M. Dhiab, N. Abid, S. Ben Zarkouna, and A. Khayati. "Intracavitary Cardiac Hydatid Cyst." Cardiovascular Surgery 11, no. 6 (December 2003): 521–25. http://dx.doi.org/10.1177/096721090301100616.

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The purpose of this study is to determine the diagnosis means, the surgical management and the prognosis of patients with intracavitary cardiac hydatid cyst. We report a series of seven patients. The diagnosis was orientated by coexisting pulmonary locations in all patients. The cyst was located in the right cardiac chambers. Cardiopulmonary bypass with aortic cross clamping and cardioplegia was necessary in all cases. The postoperative course was satisfactory for all patients. There was a recurrence of pulmonary cysts in all patients after a mean duration of 42 months. Medical treatment (Albendazole) was instituted. One late death occurred at 3 years of follow-up due to chronic right heart failure. In conclusion, cardiac hydatid cysts with intracavitary location must be suspected in patients with pulmonary or systemic embolization. Early surgical treatment is necessary and medical treatment must be instituted after surgery.
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31

Gangopadhyay, Aparna, and Subrata Saha. "The much-awaited Venezia applicator: virtues of combined intracavitary and interstitial brachytherapy in locally advanced cervical cancer." Journal of Radiotherapy in Practice 17, no. 4 (August 28, 2018): 460–61. http://dx.doi.org/10.1017/s1460396918000365.

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SummaryLocally advanced cervix cancer is a major health problem in resource-limited areas of the world. Brachytherapy following pelvic chemoradiation is challenging, as large irregular clinical target volumes need adequate dose delivery while respecting limits of normal tissue tolerance. Achieving this is practically impossible using intracavitary brachytherapy alone. Consequently, combined intracavitary and interstitial brachytherapy provides higher chances of local control.
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Brandão, Sâmia de Freitas, and Tarcísio Passos Ribeiro de Campos. "Comparative dosimetry in intracavitary balloon catheter brachytherapy with I-125 and in Cf-252 brachytherapy combined with BNCT for brain tumors." Radiologia Brasileira 46, no. 4 (August 2013): 221–26. http://dx.doi.org/10.1590/s0100-39842013000400008.

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Objective Comparative analysis of dosimetry in intracavitary balloon catheter brachytherapy with I-125 and in Cf-252 brachytherapy combined with BNCT for treatment of brain tumors. Materials and Methods Simulations of intracavitary balloon catheter brachytherapy with I-125 and in Cf-252 brachytherapy combined with BNCT were performed with the MCNP5 code, modeling the treatment of a brain tumor on a voxel computational phantom representing a human head. Absorbed dose rates were converted into biologically weighted dose rates. Results Intracavitary balloon catheter brachytherapy with I-125 produced biologically weighted mean dose rates of 3.2E-11, 1.3E-10, 1.9E-11 and 6.9E-13 RBE.Gy.h-1.p-1.s, respectively, on the healthy tissue, on the balloon periphery and on the I 1 and I 2 tumor infiltration zones. On the other hand, Cf-252 brachytherapy combined with BNCT produced a biologically weighted mean dose rate of 5.2E-09, 2.3E-07, 8.7E-09 and 2.4E-09 RBE.Gy.h-1.p-1.s, respectively on the healthy tissue, on the target tumor and on the I 1 and I 2 infiltration zones. Conclusion Cf-252 brachytherapy combined with BNCT delivered a selective irradiation to the target tumor and to infiltration zones, while intracavitary balloon catheter brachytherapy with I-125 delivered negligible doses on the tumor infiltration zones.
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van den Berge, J. Herbert, Gerhard Blaauw, Wout A. P. Breeman, Ali Rahmy, and Rinia Wijngaarde. "Intracavitary brachytherapy of cystic craniopharyngiomas." Journal of Neurosurgery 77, no. 4 (October 1992): 545–50. http://dx.doi.org/10.3171/jns.1992.77.4.0545.

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✓ Visual function, endocrinological status, and radiological outcome are reported in 31 patients harboring a cystic craniopharyngioma, who underwent 35 intracavitary brachytherapy procedures with yttrium-90. In 26 of these patients intracavitary brachytherapy was the primary treatment. The follow-up period ranged from 2 to 80 months (41 ± 22 months, mean ± standard deviation). Five patients died from tumor-related causes. Endocrine recovery was modest. Prior to brachytherapy, visual acuity was diminished in 38 eyes and field defects were present in 46. Funduscopy before treatment revealed optic atrophy in 47% of the eyes. Visual acuity improved in 29% of the eyes studied, remained stable in 13%, and deteriorated in 58%. Visual field defects improved in 28% of the eyes studied, remained stable in 20%, and deteriorated in 52%. The possible causes for deterioration in visual function are discussed. Complete resolution of 10 cysts was noted. In 12 patients the size of the cyst decreased; however, in three of these patients new cyst formation took place. The cyst size stabilized in six cases and increased in three. Although there is still a substantial degree of visual function deterioration following intracavitary brachytherapy, morbidity is otherwise low, making this treatment modality a reasonable alternative to craniotomy.
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Floch, Franck, Laurie Boissy, Didier Lanore, David Sayag, and François Serres. "Evaluation of intracavitary carboplatin chemotherapy for treatment of pleural carcinomatosis in cats: a retrospective study of eight cases." Journal of Feline Medicine and Surgery 22, no. 2 (February 5, 2019): 84–90. http://dx.doi.org/10.1177/1098612x19826401.

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Objectives The aim of this study was to evaluate the benefit of intracavitary carboplatin chemotherapy in cats with malignant pleural effusion of epithelial origin. Methods The medical records of cats with a cytological diagnosis of neoplastic pleural effusion of epithelial origin were reviewed at three referral institutions between January 2013 and June 2018. Only cats treated with intracavitary carboplatin chemotherapy were enrolled. Data collection included signalment, medical history, clinical signs, pleural effusion analysis, diagnostic imaging findings, intracavitary carboplatin chemotherapy protocol, adverse events, response to chemotherapy, outcome and underlying primary tumour, if possible. Results Eight cats met the inclusion criteria. Three cats had previous surgical removal of a tumour, including a poorly differentiated primary lung carcinoma, a uterine adenocarcinoma and a benign mammary tumour. The main clinical signs were tachypnoea and/or dyspnoea, inappetence and weight loss. Thoracic radiographs revealed marked bilateral pleural effusion in all cats. Pleural fluid analysis was consistent with a modified transudate, with malignant epithelial cells on cytology, leading to a diagnosis of pleural carcinomatosis. All cats received only one cycle of intracavitary carboplatin chemotherapy at a dose of 200–240 mg/m2. Recurrence of pleural effusion was reported in 7/8 cats within 4–15 days of chemotherapy, and death was recorded in all cats within 5–16 days, owing to recurrent pleural effusion or poor general condition. The primary cancer was suspected to be of pulmonary, mammary and pancreatic origin in four cats, two cats and one cat, respectively, and of unknown origin in the remaining cat. Conclusions and relevance In this study, intracavitary carboplatin chemotherapy seems ineffective in managing neoplastic pleural effusion of epithelial origin in cats with pleural carcinomatosis. Other cytotoxic drugs and/or techniques should be investigated in the future to improve the quality of life and survival of cats with pleural carcinomatosis.
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35

Allen-Mersh, T. G., E. J. Wilson, H. F. Hope-Stone, and C. V. Mann. "Has the Incidence of Radiation-Induced Bowel Damage following Treatment of Uterine Carcinoma Changed in the Last 20 Years?" Journal of the Royal Society of Medicine 79, no. 7 (July 1986): 387–90. http://dx.doi.org/10.1177/014107688607900704.

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Radiation-induced bowel damage occurred in 4.3% of patients treated primarily by irradiation for uterine carcinoma during the period 1962–1982. There has been a progressive rise in the incidence of radiation damage and radiation-induced rectovaginal fistula during this 20-year period. Radiation from intracavitary sources was a contributory factor in 92% of injured cases. The rising incidence of bowel damage in our patients may be due to an increase in the number of patients receiving a high rectal dose from the intracavitary source. There was a significantly ( P>0.01) higher incidence of radiation injury in cases of cervical carcinoma compared to endometrial carcinoma. This was because cervical carcinoma tended to present at a more advanced stage than endometrial carcinoma and was more frequently treated with combined external and intracavitary irradiation. There was no significant increase in the incidence of complications among patients undergoing hysterectomy.
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36

Weber, Mark D., Adam S. Himebauch, and Thomas Conlon. "Repositioning of malpositioned peripherally inserted central catheter lines with the use of intracavitary electrocardiogram: A pediatric case series." Journal of Vascular Access 21, no. 2 (July 31, 2019): 259–64. http://dx.doi.org/10.1177/1129729819865812.

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Introduction: Peripherally inserted central catheter tip migration is an infrequent event that occurs in neonatal, pediatric, and adult patients. We discuss a novel technique of utilizing intracavitary electrocardiogram to help confirm proper peripherally inserted central catheter tip repositioning, thereby reducing the need for serial radiographs. Case presentation: A case series of four patients will be discussed. The first three patients had peripherally inserted central catheter tips that were initially appropriately positioned but had later peripherally inserted central catheter tip migration. The use of intracavitary electrocardiogram was able to confirm the appropriate repositioning of the peripherally inserted central catheters without the need for serial radiographs. The fourth patient had several central lines in place, which led to difficulty in identifying the peripherally inserted central catheter tip location. The use of intracavitary electrocardiogram confirmed proper positioning of his peripherally inserted central catheter tip when standard radiographs could not provide clarity. Discussion: Several techniques have been published on methods to reposition a migrated peripherally inserted central catheter tip back to the superior vena cava/right atrial junction. These repositioning techniques often require fluoroscopic guidance or a confirmatory radiograph to assess the appropriate peripherally inserted central catheter tip location. At times, several radiographs may be required before the tip is successfully repositioned. This novel application of intracavitary electrocardiogram can help to minimize radiographs when peripherally inserted central catheter tip repositioning is required.
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37

Lee, K. S., W. K. Bae, P. N. Kim, I. Y. Kim, and B. H. Lee. "Percutaneous intracavitary treatment of aspergillomas." Journal of the Korean Radiological Society 26, no. 5 (1990): 963. http://dx.doi.org/10.3348/jkrs.1990.26.5.963.

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38

Chang, Michael Y., and David J. Sugarbaker. "Innovative therapies: intraoperative intracavitary chemotherapy." Thoracic Surgery Clinics 14, no. 4 (November 2004): 549–56. http://dx.doi.org/10.1016/s1547-4127(04)00109-4.

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39

Poalelungi, Cristian, Ion Briceag, Cristian Posea, Cerasela Barbu, Roxana Udriste, and Iuliana Ceausu. "Hysteroscopic resection of intracavitary myoma." Maturitas 124 (June 2019): 188. http://dx.doi.org/10.1016/j.maturitas.2019.04.199.

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40

Stoller, JuliusL, and AlbinoD Flores. "INTRACAVITARY IRRADIATION FOR OESOPHAGEAL CANCER." Lancet 326, no. 8468 (December 1985): 1365. http://dx.doi.org/10.1016/s0140-6736(85)92661-3.

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41

Maze, Seymour S., Morris N. Kotler, and Wayne R. Parry. "Dynamic Intracavitary Left Ventricular Obstruction." American Journal of Noninvasive Cardiology 4, no. 2 (1990): 76–82. http://dx.doi.org/10.1159/000470514.

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42

Beattie, Garth C., James Barnard, and Ajith K. Siriwardena. "Laparoscopic intracavitary debridement of peripancreaticnecrosis." Surgery 128, no. 3 (September 2000): 496. http://dx.doi.org/10.1067/msy.2000.108777.

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43

Tanaka, Toshizumi. "Intracavitary diagnosing apparatus employing ultrasound." Journal of the Acoustical Society of America 97, no. 2 (February 1995): 1368. http://dx.doi.org/10.1121/1.412105.

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44

Lima, Evelise, André Louis Lobo Nagy, and Rodrigo Abensur Athanazio. "Intracavitary pulmonary aspergilloma: endoscopic aspects." Jornal Brasileiro de Pneumologia 41, no. 3 (June 2015): 285. http://dx.doi.org/10.1590/s1806-37132015000000026.

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45

Ismailov, T. A., O. V. Evdulov, M. A. Khazamova, T. A. Ragimova, and R. A. M. Magomadov. "THERMOELECTRIC DEVICE FOR INTRACAVITARY HYPOTHERMIA." Herald of Dagestan State Technical University. Technical Sciences 46, no. 3 (November 24, 2019): 20–31. http://dx.doi.org/10.21822/2073-6185-2019-46-3-20-31.

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Objectives In this research, we aimed to develop a thermoelectric device (TED) for intracavitary hypothermia, to carry out experimental studies into its functional characteristics, as well as to develop treatment procedures using this device.Method A TED design for intracavitary hypothermia was developed, consisting of two thermoelectric batteries (TEBs) interconnected using an allmetal heat pipeline equipped with an influencing applicator and a liquid heat exchanger. Experimental studies of the device were carried out on a designed bench, which included a climatic chamber, a source of electrical energy and a temperature meter connected to a PC. Results Temperature changes at the control points of the device were recorded over time. Changes in the time taken to stabilise temperatures of the device tip, heat pipe and heat sink system at different TEB supply currents were investigated. Possible methods for treating some ENT diseases using the developed device are described.Conclusion It is shown that the temperature of the applicator is stabilised after approximately 4-4.5 minutes without load. At the same time, an increase in the current of the additional TEB from 5 to 12 A at the main TEB current of 23 A reduces the temperature from 237 K to 224 K. In the process of carrying out the procedures, the necessary level of a decrease in the temperature of a biological object can be reached at the supply current of the main and additional TEBs equal to 23 and 12 A, respectively, after 2.5 minutes. The full potential of the TED device will be realised through the developed of methods for treating ENT diseases.
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46

Li, Shidong. "Computer-aided gynecologic intracavitary brachytherapy." Medical Physics 24, no. 2 (February 1997): 335. http://dx.doi.org/10.1118/1.598082.

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47

Knower, Mark T., Peter Kavanagh, and Robert Chin. "Intracavitary Hematoma Simulating Mycetoma Formation." Journal of Thoracic Imaging 17, no. 1 (January 2002): 84–88. http://dx.doi.org/10.1097/00005382-200201000-00013.

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48

HOWELL, STEPHEN B., and CRAIG E. PFEIFLE. "Peritoneal Access for Intracavitary Chemotherapy." Cancer Drug Delivery 3, no. 2 (January 1986): 157–61. http://dx.doi.org/10.1089/cdd.1986.3.157.

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49

Hunter, R. D. "Teach-in: Modern Intracavitary Brachytherapy." British Journal of Radiology 62, Congress Suppl (August 1, 1989): S_49. http://dx.doi.org/10.1259/0007-1285-62-congress_supplement-s49.

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50

Severo, L. C., G. R. Geyer, and N. S. Porto. "Pulmonary aspergillus intracavitary colonization (PAIC)." Mycopathologia 112, no. 2 (November 1990): 93–104. http://dx.doi.org/10.1007/bf00436504.

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