Статті в журналах: "Intra-intestinal"

1

Jessurun, Jose. "Intra-Alveolar Intestinal Epithelium." International Journal of Surgical Pathology 23, no. 3 (January 27, 2015): 196–201. http://dx.doi.org/10.1177/1066896915568992.

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2

Malpas, T. J., N. MacLachlan, E. Dykes, and E. M. Kiely. "Prenatal intestinal perforation and intra-abdominal lymphangioma." Prenatal Diagnosis 27, no. 9 (2007): 882–83. http://dx.doi.org/10.1002/pd.1794.

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3

Henriques, Alexandre Cruz, Sérgio Pezzolo, Marise Gomes, Carlos Alberto Godinho, Viviane Aparecida Sotto Bazalia, and Manlio Basilio Speranzini. "Preparo intra-operatório do cólon." Revista do Colégio Brasileiro de Cirurgiões 28, no. 4 (August 2001): 271–74. http://dx.doi.org/10.1590/s0100-69912001000400007.

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OBJETIVO: Apresentar nossa experiência com o preparo intra-operatório do cólon no tratamento de pacientes com obstrução neoplásica do cólon esquerdo. MÉTODO: Vinte e três pacientes com obstrução neoplásica do cólon esquerdo foram operados no Hospital de Ensino da Faculdade de Medicina do ABC e no Hospital São Bernardo no período de 1992 a 1999. O preparo intra-operatório do cólon e a anastomose intestinal primária foram realizados em todos os pacientes e os resultados analisados. RESULTADOS: Em todos os pacientes o preparo de cólon foi adequado e a anastomose intestinal primária foi realizada em condições satisfatórias. Um paciente (4,3%) apresentou fístula bloqueada e outro (4,3%) broncopneumonia, complicações estas não relacionadas com o método de preparo intestinal; ambos evoluíram bem com tratamento clínico. Os demais não apresentaram complicações e permaneceram internados em média sete dias. CONCLUSÕES: O preparo intra-operatório do cólon é um método simples, seguro e permite a reconstrução imediata do trânsito intestinal em situações adversas.

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4

Eswaravaka, Sai Krishna, Swanit Hemant Deshpande, Roshan Chiranjeev, and Jayashri Sanjay Pandya. "Intra-abdominal small intestinal desmoid tumour mimicking GIST." BMJ Case Reports 14, no. 2 (February 2021): e237032. http://dx.doi.org/10.1136/bcr-2020-237032.

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Desmoid tumours, also known as aggressive fibromatosis, are fibromuscular neoplasms that arise from mesenchymal cell lines. Desmoid tumours are usually benign and are locally aggressive tumours. We report a case of a 31-year-old man presenting with abdominal mass associated with dyspepsia and early satiety. CT scan demonstrated a large heterogeneous mass adherent to or arising from the jejunum. The patient underwent a successful elective exploratory laparotomy with resection of the tumour arising from the wall of the ileum with a 10 cm margin. The patient had an uneventful recovery and no recurrence at 6-month follow-up. Pathology report and immunohistochemistry analysis revealed the mass to be a primary desmoid tumour of the small bowel, as the tumour was negative for c-kit and Discovered on GIST 1 (DOG-1) and positive for beta-catenin and smooth muscle actin.

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5

Wells, C. L. "Intestinal bacteria translocate into experimental intra-abdominal abscesses." Plastic and Reconstructive Surgery 78, no. 6 (December 1986): 843. http://dx.doi.org/10.1097/00006534-198678060-00102.

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6

Hoffman, James S., David R. Cave, and Desmond Birkett. "Intra-operative enteroscopy with a sonde intestinal fiberscope." Gastrointestinal Endoscopy 40, no. 2 (March 1994): 229–30. http://dx.doi.org/10.1016/s0016-5107(94)70174-1.

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7

Zhang, Li, Xiaoying Xing, Jia Ding, Xiuyun Zhao, and Gaofu Qi. "Surfactin variants for intra-intestinal delivery of insulin." European Journal of Pharmaceutics and Biopharmaceutics 115 (June 2017): 218–28. http://dx.doi.org/10.1016/j.ejpb.2017.03.005.

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8

Sakai, Tohru, Takashi Agui, and Kozo Matsumoto. "Intestinal intra-epithelial lymphocytes in LEC mutant rats." Immunology Letters 41, no. 2-3 (July 1994): 185–89. http://dx.doi.org/10.1016/0165-2478(94)90130-9.

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9

Reuter, Simone, and Srinivasan Krishnamurthy. "Intra-uterine implant (GyneFix) lost via intestinal route?" Journal of Family Planning and Reproductive Health Care 27, no. 3 (July 1, 2001): 159–60. http://dx.doi.org/10.1783/147118901101195380.

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10

Lau, W. Y., S. Y. Wong, H. Ngan, S. T. Fan, and K. K. Wong. "Intra-operative localization of bleeding small intestinal lesions." British Journal of Surgery 75, no. 3 (March 1988): 249–51. http://dx.doi.org/10.1002/bjs.1800750321.

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11

Wells, Carol L. "Intestinal Bacteria Translocate Into Experimental Intra-abdominal Abscesses." Archives of Surgery 121, no. 1 (January 1, 1986): 102. http://dx.doi.org/10.1001/archsurg.1986.01400010116016.

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12

Glushkov, N. I., Yu A. Pakhmutova, I. I. Belsky, M. G. Safin, and M. S. Shchur. "The role of abdominal hypertension in optimizing the treatment of patients with acute intestinal obstruction." HERALD of North-Western State Medical University named after I.I. Mechnikov 10, no. 1 (March 15, 2018): 33–36. http://dx.doi.org/10.17816/mechnikov201810133-36.

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The results of examination and treatment of 150 patients with acute intestinal obstruction were studied. A reliable relationship was established between the degree of intra-abdominal hypertension and the severity of the condition of patients with acute intestinal obstruction. The results of our study confirm that monitoring intra-abdominal pressure allows diagnosing acute intestinal obstruction at the initial stages of the disease, determining indications for various modes of operative interventions and the timing of their implementation, predicting the development of possible complications and lethality.

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13

Gnanadev, Praveen, Rohit Krishnappa, Hariprasad Ramachandra Naidu Taluru, Gopal Subbaiah, Gautham Mungaravalli Vasantha, Dilip Kumar Sanjeevi Nagaraj, and Geethu Damodaran. "A rare presentation of midgut malrotation as an acute intestinal obstruction and perforation in an adult." International Surgery Journal 7, no. 10 (September 23, 2020): 3459. http://dx.doi.org/10.18203/2349-2902.isj20204156.

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Midgut malrotation is a congenital anomaly seen usually in childhood. Its presentation as an acute intestinal obstruction is extremely rare in adults usually identified intra operatively. A high index of suspicion is always required when dealing with any case of acute intestinal obstruction. We report a case of young adult who presented with symptoms of acute intestinal obstruction and was diagnosed intra-operatively as cecal volvulus with impending perforation caused by midgut malrotation. Malrotation of the intestinal tract is seen due to aberrant embryology. The presentation of intestinal malrotation in adults is very rare. Contrast enhanced Computed tomography (CT) can show the abnormal anatomy clearly. Anomalies like midgut malrotation can present as an operative dilemma and awareness regarding these conditions can help surgeons deal with these conditions.

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14

Iwabuchi, Akira, Michiro Otaka, Atsushi Okuyama, Mario Jin, Setsuya Otani, Satoshi Itoh, Hideaki Sasahara, et al. "Disseminated Intra-abdominal Cystic Lymphangiomatosis with Severe Intestinal Bleeding." Journal of Clinical Gastroenterology 25, no. 1 (July 1997): 383–86. http://dx.doi.org/10.1097/00004836-199707000-00022.

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15

Rostoker, Guy, Jean‐Charles Delchier, and Marie‐Thérèse Chaumette. "Increased intestinal intra‐epithelial T lymphocytes in primary glomerulonephritis." Nephrology Dialysis Transplantation 16, no. 3 (March 1, 2001): 513–17. http://dx.doi.org/10.1093/ndt/16.3.513.

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16

Niewiarowski, Sylwia, Andrew Gogbashian, Asim Afaq, Robin Kantor, and Zarni Win. "Abdominal X-ray signs of intra-intestinal drug smuggling." Journal of Forensic and Legal Medicine 17, no. 4 (May 2010): 198–202. http://dx.doi.org/10.1016/j.jflm.2009.12.013.

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17

La Hei, E. R., and A. Shun. "Intra-operative pulse oximetry can help determine intestinal viability." Pediatric Surgery International 17, no. 2-3 (March 12, 2001): 120–21. http://dx.doi.org/10.1007/s003830000484.

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18

Pereira da Silva, Kolba, Stampini Duarte Martino, Hart, and Tako. "Soluble Extracts from Chia Seed (Salvia hispanica L.) Affect Brush Border Membrane Functionality, Morphology and Intestinal Bacterial Populations In Vivo (Gallus gallus)." Nutrients 11, no. 10 (October 14, 2019): 2457. http://dx.doi.org/10.3390/nu11102457.

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This study assessed and compared the effects of the intra-amniotic administration of various concentrations of soluble extracts from chia seed (Salvia hispanica L.) on the Fe and Zn status, brush border membrane functionality, intestinal morphology, and intestinal bacterial populations, in vivo. The hypothesis was that chia seed soluble extracts will affect the intestinal morphology, functionality and intestinal bacterial populations. By using the Gallus gallus model and the intra-amniotic administration approach, seven treatment groups (non-injected, 18 Ω H2O, 40 mg/mL inulin, non-injected, 5 mg/mL, 10 mg/mL, 25 mg/mL and 50 mg/mL of chia seed soluble extracts) were utilized. At hatch, the cecum, duodenum, liver, pectoral muscle and blood samples were collected for assessment of the relative abundance of the gut microﬂora, relative expression of Fe- and Zn-related genes and brush border membrane functionality and morphology, relative expression of lipids-related genes, glycogen, and hemoglobin levels, respectively. This study demonstrated that the intra-amniotic administration of chia seed soluble extracts increased (p < 0.05) the villus surface area, villus length, villus width and the number of goblet cells. Further, we observed an increase (p < 0.05) in zinc transporter 1 (ZnT1) and duodenal cytochrome b (Dcytb) proteins gene expression. Our results suggest that the dietary consumption of chia seeds may improve intestinal health and functionality and may indirectly improve iron and zinc intestinal absorption.

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19

A., Veena, Hanumanthaiah K. S., Manjunath K., Sandeep S., and Sai Suraj Kotera. "Isolated segmental mega-diverticulosis of ileum: a rare presentation of acute intestinal obstruction." International Surgery Journal 4, no. 6 (May 24, 2017): 2098. http://dx.doi.org/10.18203/2349-2902.isj20172419.

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We present an interesting case of acute intestinal obstruction where a woman, aged 26, presented to emergency room with constipation for 2 days and vomiting for 1 day. The examination and initial imaging suggested sub-acute intestinal obstruction, since the condition progressed she was taken to operating room for laparotomy. The intra-operative findings revealed isolated segmental mega-diverticulosis of ileum. She underwent resection of terminal ileum and caecum with ileo-colic anastomosis. Pathological evaluation of specimen showed diverticular features. Ileal diverticulosis excluding Meckel’s is an extremely rare entity and complicating into acute intestinal obstruction is strange. With a low prevalence and absence of suspicion for it, diagnosis will be made intra operatively most of the time.

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20

Wang, Gefei, Jianan Ren, Huajian Ren, Guanwei Li, and Zhiwu Hong. "Retained Intra-Abdominal Hemostatic Materials: A Rare Cause of Abscess, Intestinal Obstruction, and Intestinal Fistula." Surgical Infections Case Reports 2, no. 1 (December 2017): 35–39. http://dx.doi.org/10.1089/crsi.2017.0006.

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21

Emmertsen, K. J., P. Wara, F. B. Soerensen, and L. B. Stolle. "Intestinal Microdialysis — Applicability, Reproducibility and Local Tissue Response in a Pig Model." Scandinavian Journal of Surgery 94, no. 3 (September 2005): 246–51. http://dx.doi.org/10.1177/145749690509400314.

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Background and Aims: Microdialysis has been applied to the intestinal wall for the purpose of monitoring local ischemia. The aim of this study was to investigate the applicability, reproducibility and local response to microdialysis in the intestinal wall. Materials and Methods: In 12 pigs two microdialysis probes were inserted into the ileal wall, one in the peritoneal cavity and one in the psoas muscle. Relative recovery was measured for all probes by the no net flux method. Metabolic measurements of glucose, lactate and glycerol were performed over six hours. The ileal wall segments containing the probes were processed for histological examination. Results: Large intra- and inter-group differences in the relative recovery were found between all locations. Absolute values of metabolites showed no significant changes during the study period. The lactate in blood was 25–30% of the intra-tissue values. A severe inflammatory reaction was seen in the ileal wall around all probes. Conclusion: Measurement of the relative recovery is essential for valid measurements of metabolites when using microdialysis. The inflammatory reaction around the probe in the intestinal wall is likely to affect metabolism and measurements hereof. Therefore intestinal wall microdialysis seems confined to experimental research, and future studies should consider the intra-peritoneal approach.

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22

Eckharter, Christoph, Jörn-Markus Gass, and Valerie Kremo. "Intra-Abdominal Abscess of Unusual Origin." Praxis 112, no. 2 (February 2023): 117–19. http://dx.doi.org/10.1024/1661-8157/a003968.

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Abstract. This article describes the case of a woman who unknowingly swallowed several fishbones, one of which perforated the intestinal wall and subsequently formed an intra-abdominal abscess due to the foreign body reaction.

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23

Iwa, Masahiro, and Masakazu Sakita. "Effects of Acupuncture and Moxibustion on Intestinal Motility in Mice." American Journal of Chinese Medicine 22, no. 02 (January 1994): 119–25. http://dx.doi.org/10.1142/s0192415x94000152.

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To study the effects of acupuncture and moxibustion on intestinal motility, the distance of intra-intestinal movement of a carbon solution injected into the stomach of a mouse was evaluated. Intestinal motility was also evaluated using several drugs to accelerate or reduce intestinal motility. Our results indicate that intestinal peristalsis was accelerated significantly by acupuncture at the abdomen, but suppressed by moxibustion. The intestinal peristalsis acceleration by vagostigmin was reduced significantly by both acupuncture and moxibustion, while the reduction of intestinal peristalsis by atropin was accelerated significantly. However, no remarkable changes of intestinal peristalsis were observed with treatment by acupuncture and moxibustion after reduction by epinephrine.

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24

Chojniak, Rubens, René Aloisio da Costa Vieira, Ademar Lopes, Joaquim Costa Altenfender Silva, and Carlos Eduardo Godoy. "Intestinal paracoccidioidomycosis simulating colon cancer." Revista da Sociedade Brasileira de Medicina Tropical 33, no. 3 (June 2000): 309–12. http://dx.doi.org/10.1590/s0037-86822000000300010.

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We report a case of intestinal involvement of Paracoccidioidomycosis, in a patient considered to have colonic cancer. The diagnosis of this mycosis should be considered when an abdominal mass associated with intra-lesional calcifications on X-ray is observed. CT scans increase the findings.

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25

Zhao, Xiao-Qin, Ying Chen, Xiao-Chong Kuang, Qiang Chen, Hua Qin, Yong-Yi Meng, and Yong-Kang Ye. "Intra-abdominal high pressure induces intestinal barrier dysfunction in rats." World Chinese Journal of Digestology 21, no. 34 (2013): 3790. http://dx.doi.org/10.11569/wcjd.v21.i34.3790.

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26

Gill, J. S., Y. Yiangou, D. J. Webb, L. Meleagros, N. Benjamin, B. J. Chrysanthou, J. R. Cockcroft, R. C. Causon, A. J. Camm, and S. R. Bloom. "Peptide histidine valine: Its haemodynamic actions and pharmacokinetics in man differ from those of vasoactive intestinal peptide and peptide histidine methionine." Clinical Science 78, no. 5 (May 1, 1990): 487–92. http://dx.doi.org/10.1042/cs0780487.

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1. The effects of intravenous and intra-arterial infusion of the peptides derived from prepro-vasoactive intestinal peptide, vasoactive intestinal peptide, peptide histidine methionine and peptide histidine valine, were examined in six healthy volunteers. 2. Vasoactive intestinal peptide given intravenously caused a significant increase in heart rate and a decrease in diastolic, but not systolic, blood presure, whereas peptide histidine valine caused an increase in heart rate alone, despite higher achieved circulating peptide concentrations. Peptide histidine methionine did not affect heart rate or blood pressure. Forearm blood flow was increased by vasoactive intestinal peptide and peptide histidine valine when infused locally intra-arterially, although vasoactive intestinal peptide was more potent than peptide histidine valine. 3. Plasma concentrations of cardiodilatin (the N-terminal peptide derived from pro-atrial natriuretic peptide) were increased by intravenous infusion of vasoactive intestinal peptide, but were unaffected by peptide histidine methionine or peptide histidine valine. Circulating plasma concentrations of adrenaline and noradrenaline did not change during infusion of vasoactive intestinal peptide, peptide histidine methionine or peptide histidine valine. 4. Peptide histidine valine had a long half-life when compared with peptide histidine methionine and vasoactive intestinal peptide. 5. We conclude that peptide histidine valine is active in the human cardiovascular system and has a similar, though less potent, vasodilating action to vasoactive intestinal peptide. The higher circulating levels of peptide histidine valine found in man suggest that it may be important in modulating vascular tone.

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27

Kolba, Nikolai, Jacquelyn Cheng, Cydney D. Jackson, and Elad Tako. "Intra-Amniotic Administration—An Emerging Method to Investigate Necrotizing Enterocolitis, In Vivo (Gallus gallus)." Nutrients 14, no. 22 (November 12, 2022): 4795. http://dx.doi.org/10.3390/nu14224795.

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Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease in premature infants and a leading cause of death in neonates (1–7% in the US). NEC is caused by opportunistic bacteria, which cause gut dysbiosis and inflammation and ultimately result in intestinal necrosis. Previous studies have utilized the rodent and pig models to mimic NEC, whereas the current study uses the in vivo (Gallus gallus) intra-amniotic administration approach to investigate NEC. On incubation day 17, broiler chicken (Gallus gallus) viable embryos were injected intra-amniotically with 1 mL dextran sodium sulfate (DSS) in H2O. Four treatment groups (0.1%, 0.25%, 0.5%, and 0.75% DSS) and two controls (H2O/non-injected controls) were administered. We observed a significant increase in intestinal permeability and negative intestinal morphological changes, specifically, decreased villus surface area and goblet cell diameter in the 0.50% and 0.75% DSS groups. Furthermore, there was a significant increase in pathogenic bacterial (E. coli spp. and Klebsiella spp.) abundances in the 0.75% DSS group compared to the control groups, demonstrating cecal microbiota dysbiosis. These results demonstrate significant physiopathology of NEC and negative bacterial–host interactions within a premature gastrointestinal system. Our present study demonstrates a novel model of NEC through intra-amniotic administration to study the effects of NEC on intestinal functionality, morphology, and gut microbiota in vivo.

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28

Vasaiya, Mehulkumar K., Samir M. Shah, Vikram B. Gohil, and Milankumar S. Vaghasia. "A prospective study of 50 cases of laparoscopic intestinal anastomosis by Endo GIA universal loading stapler (green/blue) versus Endo GIA articulating reload with tri staple technology (purple)." International Surgery Journal 7, no. 11 (October 23, 2020): 3657. http://dx.doi.org/10.18203/2349-2902.isj20204667.

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Background: Intestinal anastomosis is a commonly performed procedure in surgery. Various evolvements have occurred in the field of intestinal anastomosis and recent advancement is the use of stapler in laparoscopic surgeries as a device for Gastrointestinal (GI) anastomosis. Few previous studies evaluating the clinical safety of the 2 laparoscopic linear stapling devices are available.Methods: A prospective comparative study of 50 cases which met the inclusion and exclusion criteria were included in this hospital-based study. They were randomly allocated to two groups, Group A which underwent laparoscopic intestinal anastomosis by Endo GIA tri-staple (purple) stapler and Group B which underwent Endo GIA universal loading unit (blue/green) stapler. Primary outcome was assessed in terms of intra-operative staple line bleeding, operative time and post-operative anastomotic leak.Results: Patients with laparoscopic intestinal anastomosis by Endo GIA tri-staple stapler (purple) have required less operation time as compared to Endo GIA universal loading unit. In Endo GIA universal loading unit (blue/green) 04% patients developed anastomotic leak and 40% patients had intra-operative staple line bleed while with Endo GIA tri-staple no postoperative anastomotic leak was found and 02% patients developed intra-operative staple line bleeding.Conclusions: The result of our study has shown that the Endo GIA reload tri- staple (purple) is superior in terms of having no anastomosis leak, negligent staple line bleeding and less operation time as compared with Endo GIA universal loading unit (blue/green). Thus, laparoscopic intestinal anastomosis by Endo GIA reload tri-staple stapler (purple) technology is more effective and overall more efficient.

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29

Gasche, C., G. Moser, K. Turetschek, E. Schober, P. Moeschl, and G. Oberhuber. "Transabdominal bowel sonography for the detection of intestinal complications in Crohn’s disease." Gut 44, no. 1 (January 1, 1999): 112–17. http://dx.doi.org/10.1136/gut.44.1.112.

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BackgroundThe course of Crohn’s disease is characterised by the occurrence of intestinal complications such as strictures, intra-abdominal fistulas, or abscesses. Standard diagnostic procedures may fail to show these complications, in particular fistulas.AimsTo test the value of transabdominal bowel sonography (TABS) for the detection of intestinal complications in Crohn’s disease.MethodsTABS was prospectively performed in 213 patients with Crohn’s disease in a university based inflammatory bowel disease referral centre. Thirty three underwent resective bowel surgery and were included in this study. The accuracy of TABS to detect strictures, intra-abdominal fistulas, or abscesses was compared with surgical and pathological findings.ResultsTABS was able to identify strictures in 22/22 patients and to exclude it in 10/11 patients (100% sensitivity, 91% specificity). Fistulas were correctly identified in 20/23 patients and excluded in 9/10 patients (87% sensitivity, 90% specificity). Intra-abdominal abscesses were correctly detected in 9/9 patients and excluded in 22/24 patients (100% sensitivity, 92% specificity).ConclusionsIn experienced hands TABS is an accurate method for the detection of intestinal complications in Crohn’s disease. TABS is thus recommended as a primary investigative method for evaluation of severe Crohn’s disease.

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30

Carlson, G. L. "Surgical management of intestinal failure." Proceedings of the Nutrition Society 62, no. 3 (August 2003): 711–18. http://dx.doi.org/10.1079/pns2003287.

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Surgery plays a key role in the management of both acute and, less frequently, chronic intestinal failure. Acute intestinal failure frequently requires surgical treatment when it arises as a consequence of intestinal fistulation or obstruction. In specialised clinical practice approximately 50% of acute intestinal failure is associated with intestinal fistulas and in approximately 50% of patients, this condition arises as part of the natural history or complicating treatment for Crohn's disease. A considerable proportion of such patients have abdominal infection and present complex nutritional and metabolic problems. The most important aspect of the surgical management of patients with acute intestinal failure associated with intra-abdominal infection is management of sepsis, since recovery is unlikely in the presence of active infection. Moreover, effective nutritional support and restoration of body composition is not possible if sepsis remains unresolved. Surgical strategies to deal with intra-abdominal infection may involve percutaneous drainage, laparotomy and resection of fistulating segments of intestine and, when infection is persistent and contamination extensive, laparostomy (a technique in which the abdomen is left open and allowed to heal by secondary intention). Surgical treatment should not only be timely and effective, but also aimed at preventing secondary damage to the small intestine, in order to minimise the risk of short bowel syndrome. In some cases a proximal defunctioning stoma may be required, with prolonged nutritional support, using either home total parenteral nutrition or feeding via the defunctioned distal gut (fistuloclysis), pending restoration of intestinal continuity. The role of surgical treatment for patients with short bowel syndrome is less clear. While surgery is frequently required for the management of complications of short bowel syndrome (including gallstones and possibly peptic ulcer disease), the role of intestinal lengthening and tapering procedures (to increase functional intestinal length), and artificial valves, reversed segments and colonic interposition (to reduce intestinal transit) remains controversial. For some patients with short bowel syndrome and, in particular, those with combined intestinal and hepatic failure, intestinal transplantation may become the treatment of choice as long-term results continue to improve.

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31

K. Asare, Offei, Henry E. Obaka, and Nelson K. Affram. "Gallstone ileus: a rare type of intestinal obstruction in Ghana." Ghana Medical Journal 55, no. 1 (March 31, 2021): 84–87. http://dx.doi.org/10.4314/gmj.v55i1.13.

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Gallstone ileus is an uncommon cause of intestinal obstruction in Ghana. A patient with gallstone ileus that was diagnosed intra-operatively after being treated conservatively as adhesive small bowel obstruction for ten days is reported to highlight the importance of the clinical information in this condition. A 60-year-old Chinese male with recurrent intestinal obstruction who was initially being managed at a primary healthcare facility was subsequently referred to a tertiary hospital on account of computer tomography diagnosis of an intraluminal object obstructing the bowel. He had hypokalaemia that was corrected before surgery. Intra-operatively, a 4.5cm in diameter gallstone was removed from the terminal ileum. Gallstone ileus is rare in Ghana. A high index of suspicion is required to avoid a delay in diagnosis due to the low incidence of cholelithiasis in Ghana.

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32

Thor, P., J. W. Konturek, S. J. Konturek, and J. H. Anderson. "Role of prostaglandins in control of intestinal motility." American Journal of Physiology-Gastrointestinal and Liver Physiology 248, no. 3 (March 1, 1985): G353—G359. http://dx.doi.org/10.1152/ajpgi.1985.248.3.g353.

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Intestinal myoelectric activity was measured in four conscious dogs with implanted monopolar electrodes after administration of prostaglandins (PG) and indomethacin (Indo), a potent inhibitor of PG biosynthesis. PGE2 and PGI2 given intravenously caused a dose-dependent decrease in the frequency of the migrating myoelectric complex (MMC) in fasted dogs and in postprandial spike activity in fed animals. In contrast, PGF2 alpha interrupted the MMC and caused a fedlike pattern in fasted dogs and did not affect the postprandial spike activity. Similar effects were observed after intra-arterial infusion of PGs. PGE2 and PGI2 infused into the superior mesenteric artery caused a dose-dependent inhibition of the fasted and postprandial pattern of myoelectric activity of the small bowel, whereas PGF2 alpha blocked the MMC and increased spike activity. Indo injected in a single intravenous dose caused a significant reduction in the MMC interval, and Indo infused intravenously in a constant dose induced fedlike motility pattern in fasted dogs but had little effect on the postprandial activity in these animals. This study demonstrates that exogenous PGs of E and I series administered intravenously or intra-arterially inhibit intestinal motility, whereas PGF2 alpha has opposite effects. The finding that Indo increases intestinal motility indicates that endogenous PGs are important in the physiological control of intestinal motility.

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33

Kolba, Nikolai, Cydney Jackson, and Elad Tako. "The Intra-amniotic Administration- an Emerging Method to Investigate Necrotizing Enterocolitis, In Vivo (Gallus gallus)." Current Developments in Nutrition 6, Supplement_1 (June 2022): 679. http://dx.doi.org/10.1093/cdn/nzac061.063.

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Abstract Objectives Demonstrate necrotizing enterocolitis (NEC) in a novel in vivo (Gallus gallus) model through intra-amniotic administration of dextran sodium sulfate (DSS, demonstrated agent to induce NEC), to induce NEC pathology, pathophysiology, and negative bacterial-host interactions within a premature gastrointestinal system. Methods Gallus gallus embryos were injected intra-amniotically with 1 mL DSS in DI H2O. Four treatment groups (0.1%, 0.25%, 0.5%, and 0.75% DSS) and two controls (H2O/non-injected controls) were administered. Upon hatch, blood, cecum, small intestine, and liver were collected to assess hemoglobin and intestinal permeability, intestinal microbiota alterations, intestinal morphometric assessment, and mRNA gene expression of relevant key nutrient transporters/enzymes inflammatory proteins, respectively. Results Results indicated that intestinal permeability was significantly increased post DSS exposure, and negative intestinal morphological changes were found. In the 0.50% and 0.75% DSS groups, villus surface area and goblet cell diameter have significantly decreased (p < 0.05). Furthermore, there was a significant (p < 0.05) increase in pathogenic bacterial abundance (E. coli and Klebsiella) in the 0.75% DSS group compared to the controls, demonstrating cecal microbiota dysbiosis. Taken together, these results demonstrate striking similarities between current observations in the Gallus gallus model compared with NEC patients. Conclusions This study is the first to demonstrate NEC symptoms through intra-amniotic administration of DSS in vivo (Gallus gallus), whereas previous studies have utilized rodent and pig models. The results of this study are promising evidence to investigate increased concentrations of DSS further to cause more severe NEC symptoms and identify potential novel biomarkers of less severe NEC cases. The development of such a model also allows the assessment of potential dietary bioactives that may ameliorate the effects of NEC. Funding Sources No external funding was utilized for the study.

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Fraser-Irwin, Cate, Briar McLeod, Helen Evans, Kim Herbison, Amy Kostrzewski, Kerry McIlroy, and Vidhya Makam. "Enabling intra-DHB patient-specific care for patients with intestinal failure." International Journal of Integrated Care 17, no. 3 (July 11, 2017): 110. http://dx.doi.org/10.5334/ijic.3222.

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Yorke, J., E. Agbeko, G. Amoah, and FA Abantanga. "Case Report: Intestinal Obstruction Secondary to an Intra-Abdominal Foreign Body." Journal of Medical and Biomedical Sciences 2, no. 4 (March 14, 2014): 1. http://dx.doi.org/10.4314/jmbs.v2i4.1.

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Balkan, M., M. Beyzadeoglu, K. Oysul, B. Dirican, S. Surenkok, and T. Tufan. "Retinoic Acid and Intestinal Wound Healing in Intra-operatively Irradiated Rat." Acta Chirurgica Belgica 106, no. 1 (January 2006): 73–76. http://dx.doi.org/10.1080/00015458.2006.11679838.

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Nyholm, Dag, and Per Odin. "Continuous Intra-intestinal Infusion of Levodopa/Carbidopa in Advanced Parkinson's Disease." European Neurological Review, no. 1 (2007): 45. http://dx.doi.org/10.17925/enr.2007.00.01.45.

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Strang, Steven G., Ben van der Hoven, Kim Monkhorst, Samir Ali, Esther M. M. van Lieshout, Oscar J. F. van Waes, and Michael H. J. Verhofstad. "Relation between intra-abdominal pressure and early intestinal ischemia in rats." Trauma Surgery & Acute Care Open 5, no. 1 (December 2020): e000595. http://dx.doi.org/10.1136/tsaco-2020-000595.

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BackgroundLittle is known on early irreversible effects of increased intra-abdominal pressure (IAP). Therefore, timing of abdominal decompression among patients with abdominal compartment syndrome remains challenging. The study objective was to determine the relation between IAP and respiratory parameters, hemodynamic parameters, and early intestinal ischemia.MethodsTwenty-five anesthetized and ventilated male Sprague-Dawley rats were randomly assigned to five groups exposed to IAPs of 0, 5, 10, 15, or 20 mm Hg for 3 hours. Respiratory parameters, hemodynamic parameters, and serum albumin-cobalt binding (ACB) capacity as measure for systemic ischemia were determined. Intestines were processed for histopathology.ResultsIAP was negatively associated with mean arterial pressure at 90 (Spearman correlation coefficient; Rs=−0.446, p=0.025) and 180 min (Rs=−0.466, p=0.019), oxygen saturation at 90 min (Rs=−0.673, p<0.001) and 180 min (Rs=−0.882, p<0.001), and pH value at 90 (Rs=−0.819, p<0.001) and 180 min (Rs=−0.934, p<0.001). There were no associations between IAP and lactate level or ACB capacity. No histological signs for intestinal ischemia were found.DiscussionAlthough increasing IAP was associated with respiratory and hemodynamic difficulties, no signs for intestinal ischemia were found.Level of evidencePrognostic and epidemiologic study, level II.

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Goel, M. M., N. Verma, and M. Sagar. "Disseminated intra-abdominal hydatidosis causing acute intestinal obstruction--a rare presentation." Case Reports 2010, oct01 1 (October 4, 2010): bcr0620103066. http://dx.doi.org/10.1136/bcr.06.2010.3066.

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Robertson-Malt, Suzi. "Intra-peritoneal Prophylactic Agents for Preventing Adhesions and Adhesive Intestinal Obstruction." AORN Journal 94, no. 5 (November 2011): 498–99. http://dx.doi.org/10.1016/j.aorn.2011.03.011.

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Thapa, Bijay, Anupama Thapa, and Anju Kayasthya. "Patent Vitello - Intestinal Duct: A Case Report." Journal of Nepal Paediatric Society 41, no. 1 (April 24, 2021): 103–6. http://dx.doi.org/10.3126/jnps.v41i1.30184.

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A wide variety of anomalies may occur as a result of the vitello- intestinal duct (VID) failing to obliterate completely. These anomalies occur in approximately 2% of the population and may remain silent throughout life or may present incidentally with an intra-abdominal complication. Complete patency of vitello-intestinal duct is the rarest of all the anomalies of VID. We report a case of 27 day old female presenting with pinkish umbilical mass since birth referred to us by a paediatrician as umbilical granuloma, which turned out to be patent vitello- intestinal duct.

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Abdiev, Allan, Niiazbek Mamatov, Arsen Toktosunov, Azamat Akeshov, and Sandhya Kalikiri. "Results of repeat operation for early adhesive intestinal obstruction." Biomedicine 42, no. 6 (December 31, 2022): 1272–74. http://dx.doi.org/10.51248/.v42i6.2168.

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Introduction and Aim: One of the formidable complications in abdominal surgery is early intestinal obstruction, which quickly leads to the development of severe endotoxicosis, and intra-abdominal hypertension. The objective of this study is to present the results of repeat operation of early adhesive intestinal obstruction. Methodology: There were 27 patients (13 men and 14 women) aged 17-73 years under observation, who were re-operated for early intestinal obstruction that occurred after operations on abdominal organs. Twenty-four operations were performed by laparotomic access and three by laparoscopic access. Eighteen were operated on an emergency basis and nine were operated on as per plan. Results: After diagnosis, all patients were operated on under endotracheal anesthesia with median laparotomy access, with the timing of the intervention being different. So, on the first day after the obstruction was detected, five patients were operated on, 15 patients from 24-72 hours, six patients from 3-5 days, and one patient was operated on after five days. This study shows the severity of the condition of patients with early intestinal obstruction and the complexity of treatment. Conclusion: After surgery, treatment should be comprehensive and aimed at etiopathogenesis and affect intra-abdominal pressure, endotoxicosis, and nutritional support.

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Sasaki, Akinori, Kenichi Harano, Takahiro Kogawa, Nobuaki Matsubara, Yoichi Naito, Ako Hosono, Hirofumi Mukai, Takayuki Yoshino, and Toru Mukohara. "Intestinal Perforation due to Neutropenic Enterocolitis in a Patient Treated with Bevacizumab for Ovarian Cancer." Case Reports in Oncological Medicine 2020 (June 17, 2020): 1–4. http://dx.doi.org/10.1155/2020/7231358.

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Intestinal perforation is a rare adverse event of antineoplastic therapy. However, once it occurs, it is potentially fatal. This report describes a case of intestinal perforation caused by bevacizumab in a patient with ovarian cancer who concurrently developed neutropenic enterocolitis. A 66-year-old woman diagnosed with metastatic ovarian cancer received combination chemotherapy with carboplatin, gemcitabine, and bevacizumab. On day 14, she developed grade 4 pancytopenia and febrile neutropenia, which resulted in neutropenic enterocolitis and intestinal perforation. Emergency surgery was performed, and an intestinal perforation found in the ascending colon was closed. Postoperatively, she developed an intra-abdominal abscess requiring peritoneal drainage. She was discharged from the hospital on recovery.

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Verdonk, Koen, Jeroen G. J. Jonkman, and Adriaan Dees. "Polyarteritis nodosa: An unusual cause of life-threatening intra-abdominal bleeding." Case Reports in Internal Medicine 6, no. 4 (November 24, 2019): 23. http://dx.doi.org/10.5430/crim.v6n4p23.

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Intra-abdominal arterial bleeding is a life-threatening condition, warranting immediate causal therapy. Polyarteritis nodosa is a rare type of necrotizing vasculitis that affects medium-sized arteries. We present a patient with severe arterial bleeding as the first symptom of polyarteritis nodosa. Because the bleeding took place intra-abdominal instead of gastro-intestinal, there was no macroscopic blood loss. She was successfully treated with endovascular coil embolization during angiography.

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Gabali, Ali M., Paul Priebe, and Santhi Ganesan. "Primary Melanoma of Small Intestine Masquerading as Gastrointestinal Stromal Tumor: A Case Report and Literature Review." American Surgeon 74, no. 4 (April 2008): 318–21. http://dx.doi.org/10.1177/000313480807400408.

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Malignant melanoma of the gastrointestinal tract is a rare entity among intestinal neoplasms. Primary intestinal melanoma is difficult to differentiate from metastatic melanoma, especially given that the primary cutaneous lesion has the potential to regress and disappear. In addition, melanoma by itself is a great mimicker of other neoplastic conditions and may create a major diagnostic challenge when presenting at an intra-abdominal location. Here we report a case of small intestinal melanoma in a 74-year-old female who presented with symptoms of intestinal bleeding and a preoperative clinical and radiological diagnosis of gastrointestinal stromal tumor. The initial frozen section diagnosis also favored gastrointestinal stromal tumor, however furthermore histological and immunohistochemical stain evaluation confirmed the diagnosis of intestinal melanoma.

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Daniel, E. E., M. Anvari, J. E. T. Fox-Threlkeld, and T. J. McDonald. "Local, exendin-(9—39)-insensitive, site of action of GLP-1 in canine ileum." American Journal of Physiology-Gastrointestinal and Liver Physiology 283, no. 3 (September 1, 2002): G595—G602. http://dx.doi.org/10.1152/ajpgi.00110.2002.

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Glucagon-like peptide-1 (GLP-1) modulates glucose levels following a meal, including by inhibition of gastric emptying and intestinal transport. Intra-arterial injection of GLP-1 into the gastric corpus, antrum, or pylorus of anesthetized dogs had no effect on the contractile activity of the resting or neurally activated stomach. GLP-1 injected intra-arterially inhibited intestinal segments when activated by enteric nerve stimulation but not by acetylcholine. Isolated ileum segments were perfused intra-arterially, instrumented with strain gauges to record circular muscle activity and with subserosal electrodes to stimulate enteric nerves. GLP-1 caused concentration-dependent inhibition of nerve-stimulated phasic but not tonic activity. This was absent during TTX-induced activity and partly prevented by N G-nitro-l-arginine. Exendin-(9—39), the GLP-1 antagonist, had no intrinsic activity and did not affect the actions of GLP-1. Capsaicin mimicked the effects of GLP-1 and may have reduced the effect of subsequent GLP-1. GLP-1 may mediate paracrine action on afferent nerves in the canine ileal mucosa using an unusual receptor.

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Shweta, Shweta, and Kim Vaiphei. "Intestinal atresia: histopathologist view." International Surgery Journal 8, no. 1 (December 28, 2020): 226. http://dx.doi.org/10.18203/2349-2902.isj20205885.

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Background: Intestinal atresia forms one of a common cause for intestinal obstruction in neonates. There is a debate about its pathogenesis and many theories have been suggested. Studies regarding its clinical and histomorphological features are less in Indian literature. The present study aimed to determine the clinical and histomorphological features of cases of intestinal atresia.Methods: Thirty-nine cases of intestinal atresia were studied both retrospectively (twenty-six) and prospectively (thirteen) over a period of two years. Their clinical and histomorphological features were studied.Results: Intestinal obstruction was most common clinical diagnosis. Type II atresia was most common. Ileal atresia was highest in number. Associated congenital anomalies noted were situs inversus with splenunculi, patent vitelo-intestinal duct, duplication cyst, Meckel’s diverticulum, ileocecal web, duodenal web and omphalocele. Histological features such as inspissated meconium, calcification, ulceration, fibrosis, thick-walled vessels, edema were noted.Conclusions: Findings such as mucosal edema, congestion, ulceration, submucosal edema, thick-walled blood vessels, fibrosis, hemorrhage, transmural ischemia, calcification, suggest that an intra vascular accident may be responsible for origin of the atresia.

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Pandey, Yuktansh. "A prospective study of cases of intestinal obstruction and role of conservative expectant management." International Surgery Journal 5, no. 6 (May 24, 2018): 2191. http://dx.doi.org/10.18203/2349-2902.isj20182220.

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Background: Intestinal obstruction continues to be a common surgical emergency throughout the world and its management protocol has evolved over years. In our study we aimed to provide a complete epidemiological description of intestinal obstruction in adult age group patients in a tertiary care hospital in Northern India.Methods: This is a prospective study of patients belonging to age group more than 12 years admitted in our unit with clinical features suggestive of intestinal obstruction from September 2011 to December 2013 at R. N. T. Medical College, Udaipur. The study comprised of 134 patients.Results: Intestinal obstruction contributed to 6.5% of all surgical admissions. It was nearly twice more common in males. 43% patients presented with features of acute intestinal obstruction in comparison to 57% who presented with features of sub-acute intestinal obstruction. Most common cause observed was obstruction due to intra-abdominal adhesions followed by abdominal tuberculosis 48 and 29 percent respectively. Features of intestinal obstruction resolved in 60% patients with conservative management. Adhesions, abdominal tuberculosis and malignancy counted for majority of patients with sub-acute obstruction. Emergency surgery was done in 32% of patients and 36.5 % of patients were discharged non-operatively. Planned Surgery after successful expectant management was done in 24 % patients. Most frequently seen complication was wound site collection (72.5%) followed by respiratory tract infections (49%). Total mortality in our study was 12.6% of which 41% was post-operative mortality and 59% mortality seen in patients who expired during conservative management. Conclusions: This study demonstrates that intra-abdominal adhesions and abdominal tuberculosis account for most cases of intestinal obstruction in countries like India. A watchful expectant management can be tried in patients with prior operative history and those with history of tuberculosis.

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TAKO, E., P. FERKET, and Z. UNI. "Changes in chicken intestinal zinc exporter mRNA expression and small intestinal functionality following intra-amniotic zinc-methionine administration." Journal of Nutritional Biochemistry 16, no. 6 (June 2005): 339–46. http://dx.doi.org/10.1016/j.jnutbio.2005.01.002.

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Bajaj, Anubha. "The Neoplastic Whorls-Soft Tissue Perineurioma." Journal of Clinical and Diagnostic Pathology 1, no. 2 (April 26, 2020): 17–25. http://dx.doi.org/10.14302/issn.2689-5773.jcdp-20-3292.

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Perineurioma is an exceptional, benign neoplasm entirely composed of neoplastic perineurial cells and arises from the peripheral nerve. Pertaining to location, the neoplasm predominantly demonstrates configurations such as intra-neural or extra-neural, confined to the soft tissue. Perineurioma was initially scripted by Lazarus and Trombetta in 1978 and is additionally nomenclated as localized hypertrophic neuropathy1. Extra-neural soft tissue perineurioma and mucosal (intestinal) perineurioma are frequent, in contrast to intra-neural perineurioma or localized hypertrophic neuropathy subtype1, 2.

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