Добірка наукової літератури з теми "Insuffisance rénale – chirurgie"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Insuffisance rénale – chirurgie".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Статті в журналах з теми "Insuffisance rénale – chirurgie":
Guilbart, M., P. G. Guinot, E. Guinot, O. Abou Arab, E. Zogheib, and H. Dupont. "Congestion veineuse et insuffisance rénale en postopératoire de chirurgie cardiaque." Annales Françaises d'Anesthésie et de Réanimation 33 (September 2014): A328—A329. http://dx.doi.org/10.1016/j.annfar.2014.07.556.
Montagnac, Richard, Adeline Schendel, Vincent Vuiblet, Bruno Peilleron, and Olivier Piot. "Chirurgie bariatrique, lithiase oxalo-calcique et insuffisance rénale par néphropathie oxalique." Néphrologie & Thérapeutique 7, no. 1 (February 2011): 38–45. http://dx.doi.org/10.1016/j.nephro.2010.10.009.
Chapman, David, Ron Moore, Scott Klarenbach, and Branko Braam. "Residual renal function after partial or radical nephrectomy for renal cell carcinoma." Canadian Urological Association Journal 4, no. 5 (April 18, 2013): 337. http://dx.doi.org/10.5489/cuaj.909.
Frikha, M., I. Enriquez, P. Montravers, J. Vogel, B. Dureuil, and J. M. Desmonts. "Valeur Prédictive d’une Insuffisance Rénale Observée en Réanimation Chirurgicale Aprés Chirurgie en Urgence." Annales Françaises d'Anesthésie et de Réanimation 12, no. 12 (1993): R189. http://dx.doi.org/10.1016/s0750-7658(16)30189-7.
Audren, N., A. Bataillard, G. Dessertaine, M. Rossi Blancher, A. Hebrard, M. Durand, J. F. Payen, and P. Albaladejo. "Prédire la survenue d’une insuffisance rénale après chirurgie cardiaque : doppler rénal et/ou neutrophil gelatinase associated lipocalin (NGAL) ?" Annales Françaises d'Anesthésie et de Réanimation 32 (September 2013): A192—A193. http://dx.doi.org/10.1016/j.annfar.2013.07.367.
Galtier, Florence, Caroline Rugale, Valérie Lacroix, Patrick Lefebvre, Mélanie Deloze, El Mehdi Skalli, Jean-Michel Fabre, Hélène Leray Moragues, and David Nocca. "Evolution de la fonction rénale après chirurgie bariatrique chez le diabétique de type 2 présentant une insuffisance rénale débutante." Diabetes & Metabolism 43, no. 2 (March 2017): A96—A97. http://dx.doi.org/10.1016/s1262-3636(17)30382-8.
Fayolle-Pivot, L., P. F. Wey, P. Precloux, O. Eve, M. Puidupin, F. Petitjeans, and J. Escarment. "Insuffisance rénale obstructive dans les suites d’une chirurgie hémorroïdaire réalisée sous anesthésie générale et bloc pudendal bilatéral : à propos d’un cas." Annales Françaises d'Anesthésie et de Réanimation 27, no. 12 (December 2008): 1019–22. http://dx.doi.org/10.1016/j.annfar.2008.10.010.
Claisse, G., J. M. Hougardy, E. Alamartine, P. Delanaye, N. Maillard, J. Morel, and C. Mariat. "Évaluation d’un nouvel estimateur du débit de filtration glomérulaire cinétique (KeGFR) pour prédire la survenue d’une insuffisance rénale aiguë après chirurgie cardiaque : étude AKInetic." Néphrologie & Thérapeutique 11, no. 5 (September 2015): 388. http://dx.doi.org/10.1016/j.nephro.2015.07.374.
Lavoie, Marc-Alexandre, and Matthieu Touchette. "Évaluation de la pertinence de l’application de l’algorithme d’estimation du risque cardiaque périopératoire de la Société canadienne de cardiologie publié en 2016 chez les patients subissant une chirurgie élective non cardiaque avec insuffisance rénale chronique de stade 3b et plus." Canadian Journal of General Internal Medicine 17, no. 3 (August 15, 2022): 24–32. http://dx.doi.org/10.22374/cjgim.v17i3.590.
Gabouga, Falmata Lénguébanga, Peggy Mboli-Goumba Guérendo, Edgard Djimbélé Béradjé, Battiston Juilis Ngombé-Kette, Alfred Gaudeuille, and Léon Kobangué Grénguèto. "Aspects Epidemiologiques Cliniques et Paracliniques des Fasciites Necrosantes au Centre Hospitalo-universitaire Pediatrique de Bangui (CHUPB)." European Scientific Journal, ESJ 19, no. 9 (March 31, 2023): 67. http://dx.doi.org/10.19044/esj.2023.v19n9p67.
Дисертації з теми "Insuffisance rénale – chirurgie":
Alric, Pierre. "Chirurgie aortique et fonction rénale." Montpellier 1, 2002. http://www.theses.fr/2002MON1T018.
Legouis, David. "Altération de la néoglucogenèse rénale lors de l’insuffisance rénale aiguë." Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS055.
Acute Kidney Injury (AKI) is strongly associated with mortality independently of its cause. The kidney contributes to up to 40% of systemic glucose production by gluconeogenesis during fasting and stress conditions. Whether kidney gluconeogenesis is impaired during AKI and how this might influence systemic metabolism remains unknown. Here we show that glucose production and lactate clearance are impaired during human and experimental AKI using renal arteriovenous catheterization in patients, lactate tolerance test in mice and glucose isotope labelling in rats. Single-cell transcriptomics reveal that gluconeogenesis is impaired in proximal tubule cells during AKI. In a retrospective cohort of critically ill patients, we demonstrate that altered glucose metabolism during AKI is a major determinant of systemic glucose and lactate levels and is strongly associated with mortality. Thiamine supplementation increases lactate clearance without modifying renal function in mice with AKI, enhances glucose production by renal tubular cells ex vivo, and is associated with reduced mortality and improvement of the metabolic pattern in a retrospective cohort of critically ill patients with AKI. This study highlights an unappreciated systemic role of renal glucose and lactate metabolism in stress conditions, delineates general mechanisms of AKI-associated mortality and introduces a potential intervention targeting metabolism for a highly prevalent clinical condition with limited therapeutic options
Bojan, Mirela. "MARQUEURS PRONOSTIQUES DE L’INSUFFISANCE RENALE AIGUË CHEZ LE NOUVEAU-NE ET LE NOURRISSON BENEFICIANT D’UNE CHIRURGIE CARDIAQUE." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA11T028.
Acute kidney injury (AKI) is common following congenital cardiac surgery withcardiopulmonary bypass (CPB). To date, no prophylactic intervention has proved to beuseful for the prevention of postoperative AKI. When AKI occurs, treatment is mainlysupportive and, when severe, requires renal replacement therapy (RRT). Several reportshave shown better outcome with early RRT in adults with multiorgan failure. No such data isavailable in children undergoing cardiac surgery, and criteria for RRT vary among centres.The definition of AKI is a reduction in the glomerular filtration rate (GFR), and the diagnosis isbased on an increase in serum creatinine (sCr) and a reduction in urine output; these arefunctional criteria, translating the consequences of glomerular injury. However, it iscommonly admitted that the first pathophysiologic finding in AKI following cardiac surgery istubular injury. Besides, the functional criteria are late, are not specific, and may delay thediagnosis of AKI. Novel AKI biomarkers, specific of tubular injury are available nowadays,with urine Neutrophil Gelatinase-Associated Lipocaline (uNGAL) being the most popular –they may allow for an early diagnosis of AKI.Objectifs. The aim of this work was: (i) explore associations between the delay to RRT, earlyand mid-term outcome in patients younger than 1 year of age who develop AKI followingcardiac surgery; (ii) assess the accuracy of early sCr variations and (iii) of uNGAL for severeAKI in two similar populations aged < 1 year.Methods. A single centre retrospective cohort of patients aged < 1 year undergoing surgeryover 10 years was used to asses the association between the delay to RRT et short and midtermsurvival. Inverse probability of treatment weighting was used to reduce bias due tochanges in practices that occurred during the long study period. A second retrospectivecohort of patients aged < 1 year undergoing surgery over 3 ½ years was used to asses theaccuracy of early sCr variations for the diagnosis of severe AKI. Finally, a third prospectivecohort of patients aged < 1 year undergoing surgery over 18 month was used to asses theaccuracy of uNGAL for the diagnosis of severe AKI. The study of both sCr and uNGAL useda similar methodology: first clustering of all individual trajectories of variation, enablingassessment of the association with a composite outcome (need for RRT and/or death) andidentification of the « normally expected » postoperative evolution of both sCr an uNGAL,associated with the best outcome; second, use of ROC curves and reclassification tables toassess the accuracy of each biomarker for the diagnosis of AKI.Results. Early RRT, initiated on the day of surgery or on day 1 following surgery, wasassociated with a 45% increase in 30-days and 90-days survival. Early sCr variation, within 2days of surgery, had a good specificity but was lacking sensitivity and discrimination for thediagnosis of severe AKI; the « expected » sCr evolution was a persistent 25% postoperativereduction relative to baseline. uNGAL had good discrimination and predictive ability for thecomposite outcome; uNGAL concentration increased within 2 hours of surgery, andremained high in patients with the composite outcome.Discussion and conclusions. If early RRT improves outcome in patients aged < 1 yearswith AKI following cardiac surgery, then it becomes important to perform an early diagnosisof severe AKI. To date, diagnosis of AKI is based on early sCr variations, but such variationslack sensitivity and discrimination for the diagnosis of severe AK. On the other hand, theincrease in uNGAL within hours of surgery has excellent accuracy for the diagnosis of severeAKI, making uNGAL a promising AKI biomarker in patients aged < 1 year undergoing cardiacsurgery with cardiopulmonary bypass
Cantini, Olivier. "Utilisation de cisatracurium en perfusion continue chez l'insuffisant rénal." Bordeaux 2, 1999. http://www.theses.fr/1999BOR23038.
Soria, Caroll. "Etude de la thiopurine-méthyltransférase chez les transplantés rénaux traités à l'azathioprine." Paris 5, 1992. http://www.theses.fr/1992PA05P216.
Maanaoui, Mehdi. "La greffe d'îlots pancréatiques chez le patient diabétique transplanté rénal." Electronic Thesis or Diss., Université de Lille (2022-....), 2023. https://pepite-depot.univ-lille.fr/ToutIDP/EDBSL/2023/2023ULILS071.pdf.
Pancreatic islet transplantation is an innovative cellular therapy for the management of diabetes in patients with type 1 diabetes. Currently, there are few studies that address the prognostic impact of islet transplantation in patients with type 1 diabetes who have received a kidney transplant or the determinants of transplantation success in this population. Furthermore, the definition of diabetes is evolving, with the dichotomy between type 1 and type 2 diabetes fading in favor of diabetes classifications based on the patient's clinical and biological phenotype. Pancreatic islet transplantation could potentially be expanded to other profiles of patients with diabetes and a kidney transplant, especially if there's evidence of insulin secretion deficiency. Thus, the objective of this thesis is to determine the role of pancreatic islet transplantation in patients with diabetes and a kidney transplant.In the first section, we present the results of a nationwide cohort study assessing the effect of pancreatic islet transplantation following kidney transplantation compared to insulin alone in patients with type 1 diabetes. Islet-after-kidney recipients were matched to control patients using a time-dependent propensity score. After matching, pancreatic islet transplantation is associated with a reduction in the combined risk of death and return to dialysis, as well as the isolated risk of death. This study emphasizes the importance of considering islet transplantation as a full-fledged therapeutic alternative, especially in regions where it is not reimbursed or available.The second section explores the determinants of islet loss of functionality, in particular the repercussions of alloimmunity. The results of a single-center study suggest that preformed DSA and early de novo DSA have little impact on islet transplantation outcomes, but late de novo DSA is temporally associated with impaired metabolic results. No cases of cross-sensitization between pancreatic islets and the underlying kidney in recipients were described, neither in the study nor in the literature.The last section focuses on evaluating the insulin profile in patients with type 2 diabetes and a kidney transplant, through the calculation of HOMA-2 scores, to extract the impact of insulin secretion. Analysis of a single-center retrospective cohort shows an association between insulin resistance evaluated by HOMA-2 and the risk of allograft loss, while insulin secretion was only associated with metabolic balance. However, given the relationship between metabolic balance and the likelihood of death and graft loss in kidney transplant patients with diabetes, pancreatic islet transplantation could be part of the therapeutic arsenal in a personalized medicine approach for these patients.In conclusion, this thesis advocates for personalized diabetes medicine in kidney transplant patients, promoting the integration of pancreatic islet transplantation as a key component in the therapeutic strategy for these individuals
Rupp, Paul-Antoine. "Spondylarthropathie destructive découverte par une paraplégie progressive chez un patient dialysé depuis 12 ans, évolution favorable aprés chirurgie." Bordeaux 2, 1993. http://www.theses.fr/1993BOR2M119.
Perrotti, Andréa. "Impact pronostique des biomarqueurs en chirurgie cardiaque." Thesis, Bourgogne Franche-Comté, 2017. http://www.theses.fr/2017UBFCE003.
A biomarker is a biological parameter absent or expressed at a basal Ievel in physiological situation, and present or overexpressed in the event ofalteration of the corresponding tissue function. The dosage ofsome biomarkers makes it possible to follow or even anticipate the occurrence of a postoperative complication, and allows a rapid and adapted management ofthis complication. Patients with heart surgery are exposed to several types of complications. The most important are residual myocardial ischemia and perioperative infarction, respiratory complications, renal insufficiency and sternal wound infections. Each c these complications increases post-operative morbidity and mortality. The determination of the cardiac TROPONINE I has shown its interest in the detection ofresidual myocardial ischemia and the diagnosis ofperioperative infarction. We tested the cardiac Troponin I ratio at 12 h / cardiac Troponin I at 6 h in the detection ofpost-operative residual myocardial ischemia. We have demonstrated that a ratio oftroponin Hl2 / H6> 1.3 makes it possible to detect the lesions of the grafts after coronary bypass surgery. Their early detection makes it possible to prevent the pejorative evolution of the grafts. NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (NGAL), is a marker ofrenal failure never tested in patients with chronic renal failure in preoperative cardiac surgery. We have demonstrated that plasma NGAL is a robust marker for the development of acute renal failure in postoperative cardiac surgery in patients with pre-operative renal failure. An NGAL level at the 6th hour above 155ng / ml is an independent risk factor for the occurrence of postoperative acute renal failure. ENDOCAN is a marker ofpulmonary involvement, which has never been tested in cardiac surgery. We propose to: 1) Determine the kinetics ofEndocan in the inflammatory context of the CEC, 2) Assess the Iink between the decrease in circulating endocan and the risk ofprogress towards respiratory failure ofseptic origin or Inflammatory, 3) Compare endocan kinetics with other markers of inflammation and infection: Protein C Reactive (CRP) and procalcitonin (PCT), and 4) Assess the prognostic value of the rate of inflammation, Endocan in the occurrence ofpostoperative respiratory deaths. We conducted a pilot study that found that 6 hours after the procedure, patients with postoperative pulmonary infection had significantly higher levels ofEndocan than patients without pulmonary infection. This pilot study showed a potential interest in designing a specific study, which was submitted for publication. We performed a prospective study, which included 155 patients. The results confirm the results of the pilot study, namely that the preoperative and 6-hour Endocan is predictive ofpostoperative pulmonary involvement
Kahli, Abdelkader. "Chirurgie cardiaque sous circulation extra-corporelle et ses biomarqueurs : rôle du Growth / Différentiation Factor 15 (GDF 15) : études cliniques." Thesis, Dijon, 2016. http://www.theses.fr/2016DIJOPE02/document.
Ischemic cardiac diseases are the most frequent and deleterious pathologies leading to important cardiovascular-related mortality worldwide. One of the alternative therapies consists to treat these patients using cardiac surgery. Cardiopulmonary bypass was developed to greatly improve this surgical procedure. However, some adverse effects can occur during cardiac surgery associated with cardiopulmonary bypass due to the inflammatory response. This phenomenon is the result of various mechanisms including oxidative stress and inflammatory cytokines which lead to multi-organ failure and then to myocardial and renal injuries occurring during the peri- and post-operative periods.The first part of this work was designed to evaluate in the context of cardiac surgery the kinetics of plasma GDF-15 levels, an oxidative stress and inflammation related cytokine. Our prospective study demonstrated for the first time the kinetic increase in plasma GDF-15 levels which were associated to postoperative cardiac and renal injuries.Currently, operative risk evaluation is based on score calculation including clinical criteria. These risk scores present some limitations. Concerning other cardiac patients out of surgical fields, the risk assessment is defined using clinical parameters and biomarkers evaluation (cardiac troponin, BNP, Nt-proBNP). Thus, we aimed to determine whether pre-operative GDF-15 as plasma biomarker could help to identify patients at high risk of renal injuries. We found that patients with the highest pre-operative plasma GDF-15 levels are at risk for post-operative acute kidney injury
Beaubien-Souligny, William. "L’insuffisance rénale aiguë congestive en chirurgie cardiaque." Thesis, 2020. http://hdl.handle.net/1866/25284.
Contexte : Chaque année, plus de 2 millions de personnes subissent une chirurgie cardiaque, dont 15 000 Canadiens (1). L’insuffisance rénale aiguë demeure une complication fréquente chez les patients subissant une chirurgie cardiaque atteignant une incidence jusqu’à 39 % dans la période postopératoire (2). Cette complication est associée à une augmentation du risque de mortalité à court et long termes. Plusieurs mécanismes peuvent engendrer l’insuffisance rénale aiguë dans la période peropératoire, ce qui complexifie la prévention et le traitement. Parmi ceux-ci, divers facteurs peuvent engendrer une augmentation des pressions veineuses menant à un état de congestion systémique qui affecte la fonction des reins ainsi que celle des autres organes vitaux. La détection de la congestion au chevet des patients durant la période intraopératoire et postopératoire pourrait permettre d’identifier les individus à risque de développer des complications de nature congestive telles que l’insuffisance rénale aiguë ainsi que de mettre en place des stratégies de prévention et de traitement. L’échographie Doppler est une technologie non invasive qui permet d’évaluer la vélocité du sang dans le réseau veineux. La diminution de la compliance veineuse entraine l’apparition d’altérations du flot veineux de la veine porte et des veines intrarénales. Les objectifs des travaux présentés dans cette thèse étaient les suivants : déterminer la prévalence ainsi que les facteurs prédicteurs de l’apparition de ces altérations durant la période peropératoire; déterminer si la détection de ces altérations est en mesure de prédire l’apparition d’insuffisance rénale aiguë dans la période postopératoire; et déterminer quelle est la signification clinique de l’apparition de ces signes dans la période postopératoire immédiate. Résultats principaux : Les travaux contenus dans cette thèse comportent trois études de cohorte comprenant 1497 examens échographiques chez 362 patients. La présence d’altération du flot veineux a été observée chez une proportion substantielle des patients durant la période post-opératoire, allant de 10.8% à 24.3% selon le site intérrogé et le moment où l’examen est effectué. Nous avons observé des associations entre les altérations du flot veineux et les autres marqueurs de congestion incluant la pression veineuse centrale, la mesure du NT-pro-BNP et la balance liquidienne. De plus, nous avons observé que la pulsatilité du flot portal est corrélée aux altérations du signal Doppler dans les veines intrarénales. Grâce à des examens répétées effectuées dans une cohorte de 145 patients, nous avons observé que la pulsatilité du flot portal et la présence d’un profil compatible avec une anomalie sévère du flot intrarénal veineux étaient associées indépendamment avec la survenue subséquente d’insuffisance rénale aiguë durant la période postopératoire. Une réanalyse de ces données nous a permis de constater qu’un système de gradation combinant la présence des altérations du flot veineux à plusieurs sites, incluant les veines hépatiques, la veine porte et les veines intrarénales, au moment de l’admission aux soins intensifs permet d’indentifier les patients qui développeront une insuffisance rénale aiguë avec une spécificité élevée. Conclusions : Dans le contexte de la chirurgie cardiaque, l’échographie Doppler peut être utilisée au chevet afin d’indentifier des altérations du flot veineux périphérique suggestives d’un phénomène de congestion et d’anticiper les complications de nature congestive tel que l’insuffisance rénale aiguë.