Дисертації з теми "Inhibitory Neurons"
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Husson, Zoé. "Glycinergic neurons and inhibitory transmission in the cerebellar nuclei." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066279/document.
Повний текст джерелаThe cerebellum is composed of a three-layered cortex and of nuclei and is responsible for the learned fine control of posture and movements. I combined a genetic approach (based on the use of transgenic mouse lines) with anatomical tracings, immunohistochemical stainings, electrophysiological recordings and optogenetic stimulations to establish the distinctive characteristics of the inhibitory neurons of the cerebellar nuclei and to detail their connectivity and their role in the cerebellar circuitry.We showed that the glycinergic inhibitory neurons of the cerebellar nuclei constitute a distinct neuronal population and are characterized by their mixed inhibitory GABAergic/glycinergic phenotype. Those inhibitory neurons are also distinguished by their axonal plexus which includes a local arborization with the cerebellar nuclei where they contact principal output neurons and a projection to the granular layer of the cerebellar cortex where they end onto Golgi cells dendrites. Finally, the inhibitory neurons of the cerebellar nuclei receive inhibitory afferents from Purkinje cells and may be contacted by mossy fibers or climbing fibers.We provided the first evidence of functional mixed transmission in the cerebellar nuclei and the first demonstration of a mixed inhibitory nucleo-cortical projection. Overall, our data establish the inhibitory neurons as the third cellular component of the cerebellar nuclei. Their importance in the modular organization of the cerebellum and their impact on sensory-motor integration need to be confirmed by optogenetic experiments in vivo
Li, Yan. "Inhibitory synpatic transmission in striatal neurons after transient cerebral ischemia." Connect to resource online, 2009. http://hdl.handle.net/1805/2021.
Повний текст джерелаTitle from screen (viewed on December 1, 2009). Department of Anatomy and Cell Biology, Indiana University-Purdue University Indianapolis (IUPUI). Advisor(s): Zao C. Xu, Feng C. Zhou, Charles R. Yang, Theodore R. Cummins. Includes vitae. Includes bibliographical references (leaves 115-135).
Bampasakis, Dimitris. "Inhibitory synaptic plasticity and gain modulation in cerebellar nucleus neurons." Thesis, University of Hertfordshire, 2016. http://hdl.handle.net/2299/17179.
Повний текст джерелаWang, Hui. "Structural and functional studies of the neuronal growth inhibitory factor, human metallothionein-3." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/HKUTO/record/B39559014.
Повний текст джерелаWang, Hui, and 王暉. "Structural and functional studies of the neuronal growth inhibitory factor, human metallothionein-3." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B39559014.
Повний текст джерелаMardinly, Alan Robert. "Regulation of Synapse Development by Activity Dependent Transcription in Inhibitory Neurons." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:10739.
Повний текст джерелаChik, Tai-wai David. "Global coherent activities in inhibitory neural systems Chik Tai Wai David." Click to view the E-thesis via HKUTO, 2004. http://sunzi.lib.hku.hk/hkuto/record/B31040408.
Повний текст джерелаLofredi, Roxanne [Verfasser]. "Characterization of inhibitory and projection specific neurons of the presubiculum / Roxanne Lofredi." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2017. http://d-nb.info/1126505005/34.
Повний текст джерелаPangalos, Maria. "Analysis of hippocampal inhibitory and excitatory neurons during sharp wave-associated ripple." Doctoral thesis, Humboldt-Universität zu Berlin, Lebenswissenschaftliche Fakultät, 2016. http://dx.doi.org/10.18452/17590.
Повний текст джерелаIn the hippocampus there are different patterns of activity also known as network oscillations. These oscillations express different frequencies, and one oscillation is the ripple oscillation at around 200 Hz. It is associated with an activity wave called sharp wave and form a so-called sharp wave-ripple complex (SWR). SWRs are implicated in memory consolidation. In this thesis we investigate mechanisms underlying sharp wave-ripple complexes. In the first part of this thesis I examine one type of inhibitory neurons in the region CA1 of the hippocampus during SWR. Oriens-lacunosum moleculare (O-LM) interneurons receive strong excitatory synaptic input during ripples. This input arrives after the ripple maximum and is phase locked with the ripple cycles. Around half of the probed O-LM cells fire during the SWR and thereby show an active participation during SWR. The magnitude of excitation in O-LM cells and the ratio between excitation and inhibition determine if an O-LM cell is active during the SWR. Action potentials in these cells occur late during the SWR and are phase locked. In the second part the synaptic input onto excitatory pyramidal cells were investigated during ripple oscillations. Previous work has identified two different types of pyramidal cells in area CA1. We recorded from deep and superficial pyramidal cells. For both types of pyramidal cells the inhibitory and excitatory synaptic inputs temporally associated with ripples express comparable strength. In the last and third part, I recorded SWR in the CA2 region of the hippocampus and showed incidence, frequency and amplitude of ripples and SWR. Pyramidal cells in the CA2 region are integrated into the network during SWR. They receive SWR associated synaptic input during SWR. The excitatory and inhibitory synaptic inputs in CA2 pyramidal cells were investigated in detail. Phase analysis show phase locking of local field potential ripples and synaptic inputs to the ascending phase of the ripple cycle.
Chik, Tai-wai David, and 戚大衛. "Global coherent activities in inhibitory neural systems: Chik Tai Wai David." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2004. http://hub.hku.hk/bib/B31040408.
Повний текст джерелаDobie, Frederick Andrew. "Molecular and cellular mechanisms of inhibitory synapse formation in developing rat hippocampal neurons." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/41933.
Повний текст джерелаScheimann, Jessie R. "Sex Differences in the Role of Glucocorticoid Receptors in Excitatory vs Inhibitory Neurons." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1554213356486937.
Повний текст джерелаBlurton-Jones, Mathew Mark. "Estrogen modulates neurotrophin systems in the brain via putative actions on inhibitory neurons /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2002. http://wwwlib.umi.com/cr/ucsd/fullcit?p3064473.
Повний текст джерелаBackström, Eva. "Expression of stimulatory and inhibitory molecules in interactions between natural killer cells and neurons /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-516-6.
Повний текст джерелаDoolin, Richard Edward. "An odorant-suppressible chloride conductance mediates inhibitory receptor potentials in lobster olfactory receptor neurons." [Gainesville, Fla.] : University of Florida, 2002. http://purl.fcla.edu/fcla/etd/UFE1001136.
Повний текст джерелаAustin, Mason. "Is the lateral septum's inhibitory influence on the amygdala mediated by GABA-ergic neurons?" Diss., Connect to the thesis, 2004. http://hdl.handle.net/10066/741.
Повний текст джерелаJalil, Sajiya Jesmin. "Stability Analysis of Phase-Locked Bursting in Inhibitory Neuron Networks." Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/math_diss/7.
Повний текст джерелаNg, Yu Pong. "Leukemia inhibitory factor receptor signaling in NGF-induced neuronal differentiation of PC12 cells /." View abstract or full-text, 2004. http://library.ust.hk/cgi/db/thesis.pl?BICH%202004%20NG.
Повний текст джерелаIncludes bibliographical references (leaves 134-172). Also available in electronic version. Access restricted to campus users.
Chéry, Nadège. "Inhibitory control of neurons in the marginal zone (lamina I) of the rat spinal cord." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape4/PQDD_0032/NQ64534.pdf.
Повний текст джерелаMcDougal, Robert A. "Excitatory-Inhibitory Interactions as the Basis of Working Memory." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1313004219.
Повний текст джерелаBeebe, Nichole L. "Perineuronal nets and the inhibitory circuitry of the auditory midbrain: evidence for subtypes of GABAergic neurons." Kent State University / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=kent1468938365.
Повний текст джерелаLayne, Robert Michael. "The AIB interneurons are modulated by excitatory and inhibitory signaling pathways to shape aversive behaviors in response to 1-octanol." University of Toledo / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1445452178.
Повний текст джерелаGuilbert, Erin. "Inhibitory role of d-series resolvins in the cellular response to painful stimuli in trigeminal ganglion neurons." Thesis, Boston University, 2012. https://hdl.handle.net/2144/12405.
Повний текст джерелаResolvins (Rv) are molecules that are responsible for the active resolution of inflammation. Recent studies have suggested that the resolvins are capable of inhibiting pain associated with inflammation. Our goal was to determine the effects of RvD1, aspirin triggered (AT)-RvD1, and RvD2 on the intracellular calcium concentration ([Ca2+]i) response to the painful stimulus, capsaicin, in cultured trigeminal ganglion neurons. Neuronal cells of the rat trigeminal ganglia were isolated and cultured on 35 mm glass bottom dishes that had been treated with poly-D lysine and laminin. Cells were incubated in the presence or absence of RvD1 , RvD2, or AT-RvD1. Cells were then loaded with Fura-2 to detect changes in [Ca2+]i..[Ca2+]i was measured in response to capsaicin administration. RvD1, AT-RvD1, and RvD2 significantly inhibited the increase in [Ca2+]i in response to capsaicin. In addition the localization of lipoxin A4 (ALX) receptor that can be used by RvD1 and AT-RvD1 and nestin that indicates neurons was detected in the plated cells using immunofluorescence microscopy. The ability of D-series resolvins to inhibit the Ca2+i response to capsaicin suggests that this type of resolvin has the potential to be effective endogenous analgesics in pain conditions of the face and head. The presence of the ALX receptor on the cells of the trigeminal ganglion supports the hypothesis that RvD1 and AT-RvD1 could inhibit pain through interaction with ALX.
Kaplan, Eitan S. "Visual cortical plasticity : the role of parvalbumin expressing inhibitory neurons and abnormalities in models of neurodevelopmental disorders." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/103210.
Повний текст джерелаCataloged from PDF version of thesis. Vita.
Includes bibliographical references (pages 121-134).
The roles played by cortical inhibitory neurons in experience-dependent plasticity and learning are not well understood. Here we evaluate the participation of parvalbumin-expressing (PV+) GABAergic neurons in two forms of experience-dependent modification of primary visual cortex (V1) in adult mice: ocular dominance (OD) plasticity resulting from monocular deprivation and stimulus-selective response potentiation (SRP) resulting from supplemental visual experience. These two forms of plasticity are triggered by different events but lead to a similar increase in visual cortical response. Both also require the NMDA class of glutamate receptor (NMDAR). However, we find that PV+ inhibitory neurons in V1 play a critical role in the expression of SRP and its behavioral correlate of familiarity recognition, but not in the expression of OD plasticity. Furthermore, NMDARs expressed within PV+ cells play a critical role in SRP, but not in the induction or expression of adult OD plasticity. We also explore the use of visual cortical plasticity paradigms to better understand the function of proteins implicated in autism spectrum disorders (ASDs) and schizophrenia. We find that NMDAR-dependent long-term depression (LTD) and deprived-eye depression in layer 4 of V1 require metabotropic glutamate receptor 5 (mGluR5) signaling during postnatal development. Additionally, schizophrenia-associated protein neurogranin overexpression in V1 disrupts juvenile ocular dominance plasticity. Finally, we evaluate SRP in two models of ASDs associated with excitatory/ inhibitory imbalance: Rett syndrome (RTT) and tuberous sclerosis complex (TSC). Surprisingly, mouse models of RTT and TSC exhibit abnormal SRP phenotypes, but in opposite directions.
by Eitan S. Kaplan.
Ph. D. in Neuroscience
Baca, Serapio Michael. "Inhibitory motor neurons are essential for the production of local bending in the medicinal leech (Hirudo medicinalis) /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2005. http://wwwlib.umi.com/cr/ucsd/fullcit?p3167858.
Повний текст джерелаBihun, Marzena Maria. "Functional relevance of inhibitory and disinhibitory circuits in signal propagation in recurrent neuronal networks." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31148.
Повний текст джерелаUre, Daren Raymond. "Retrograde signaling and retrograde axonal transport of leukemia inhibitory factor and nerve growth factor by cultured sympathetic neurons." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/nq21648.pdf.
Повний текст джерелаFujiyama, Tomoyuki. "Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1." Kyoto University, 2012. http://hdl.handle.net/2433/157456.
Повний текст джерелаMiyazaki, Yoshiya. "Xenon Has Greater Inhibitory Effects on Spinal Dorsal Horn Neurons than Nitrous Oxide in Spinal Cord Transected Cats." Kyoto University, 2000. http://hdl.handle.net/2433/181269.
Повний текст джерелаWhittaker, Maximilian Anthony Erik. "Modulation of fast-spiking interneurons using two-pore channel blockers." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31252.
Повний текст джерелаCleland, Thomas A. "Inhibitory glutamate receptor channels : characterization and modulation in cultured lobster stomatogastric neurons : or it's amazing it works at all /." Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 1997. http://wwwlib.umi.com/cr/ucsd/fullcit?p9724889.
Повний текст джерелаDelgado, Arriagada Ricardo Alfonso [Verfasser]. "Molecular components involved in the inhibitory responses and Ca2+ clearance from the cilia of olfactory receptor neurons / Ricardo Alfonso Delgado Arriagada." Hannover : Technische Informationsbibliothek und Universitätsbibliothek Hannover (TIB), 2011. http://d-nb.info/1019723386/34.
Повний текст джерелаPangalos, Maria [Verfasser], Richard [Gutachter] Kempter, Dietmar [Gutachter] Schmitz, and Nikolai [Gutachter] Axmacher. "Analysis of hippocampal inhibitory and excitatory neurons during sharp wave-associated ripple / Maria Pangalos ; Gutachter: Richard Kempter, Dietmar Schmitz, Nikolai Axmacher." Berlin : Lebenswissenschaftliche Fakultät, 2016. http://d-nb.info/1113686162/34.
Повний текст джерелаAvigdor, Mauricio. "Natural Neuronal Variation in a Complex Neuroendocrine Pathway: Effect of Selection for Photoperiod Responsiveness on the Density and Location of Mature GNRH-Releasing Neurons in Inhibitory and Excitatory Photoperiods." W&M ScholarWorks, 2004. https://scholarworks.wm.edu/etd/1539626458.
Повний текст джерелаPainter, Palak Rajeshkumar. "Quantitative analysis of glycinergic neurons including Ia inhibitory interneurons in the ventral spinal cord using a BAC-GlyT2-eGFP transgenic mouse model." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1347911464.
Повний текст джерелаBredack, Christoph [Verfasser], Sonja [Akademischer Betreuer] Wojcik, Erwin [Akademischer Betreuer] Neher, and Ahmed [Akademischer Betreuer] Mansouri. "Genetic Targeting and Analysis of Parvalbumin and VGLUT3 Expressing Inhibitory Neurons / Christoph Bredack. Gutachter: Sonja Wojcik ; Erwin Neher ; Ahmed Mansouri. Betreuer: Sonja Wojcik." Göttingen : Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2012. http://d-nb.info/1042305536/34.
Повний текст джерелаMarx, Manuel [Verfasser]. "Intralaminar and translaminar microcircuits involving excitatory and inhibitory neurons in layer 6B of the somatosensory rat barrel cortex : a morphological, physiological and immunofluorescence study / Manuel Marx." Aachen : Hochschulbibliothek der Rheinisch-Westfälischen Technischen Hochschule Aachen, 2014. http://d-nb.info/1051528771/34.
Повний текст джерелаDuguid, Ian Charles. "Inhibitory synaptic plasticity in the cerebellum." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.368689.
Повний текст джерелаNakamizo, Tomoki. "Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons." Kyoto University, 2003. http://hdl.handle.net/2433/148692.
Повний текст джерелаChow, Wei-Yan. "Inhibitory neuron lamination in the developing zebrafish retina." Thesis, University of Cambridge, 2015. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708976.
Повний текст джерелаTarczy-Hornoch, Kristina. "Physiology of synaptic inputs to layer IV of cat visual cortex." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.337608.
Повний текст джерелаDe, Sousa Sara Luisa Mellor. "Effects of the general anaesthetics isoflurane and xenon on synaptic transmission in isolated hippocampal neurones." Thesis, Imperial College London, 1999. http://hdl.handle.net/10044/1/8593.
Повний текст джерелаLanducci, Elisa. "Modeling Rett syndrome with iPSCs-derived neurons." Doctoral thesis, Università di Siena, 2018. http://hdl.handle.net/11365/1051069.
Повний текст джерелаJalics, Jozsi Z. "EXISTENCE OF SLOW WAVES IN MUTUALLY INHIBITORY THALAMIC NEURONAL NETWORKS." The Ohio State University, 2002. http://rave.ohiolink.edu/etdc/view?acc_num=osu1023324103.
Повний текст джерелаZeki, Mustafa. "DISCRETE ANALYSIS OF SYNCHRONIZED OSCILLATIONS IN EXCITATORY-INHIBITORY NEURONAL NETWORKS." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1282065976.
Повний текст джерелаChan, Yuen-man, and 陳婉文. "Effect of caspase inhibitors on the survival and regeneration of injured spinal motoneurons." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31242893.
Повний текст джерелаNgo, Dung. "Elucidating the Cellular and Molecular Changes of Dopaminergic Neurons by Rotenone-Induced Neurodegeneration in Zebrafish." Thesis, Université d'Ottawa / University of Ottawa, 2018. http://hdl.handle.net/10393/37921.
Повний текст джерелаYaraghi, Zahra. "The Neuronal Apoptosis Inhibitory Protein, NAIP, analysis of human and murine genetics." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0021/NQ46555.pdf.
Повний текст джерелаJordan, Russell S. (Russell Stall). "Investigation of Inhibitory Influences in Neuronal Monolayer Networks Cultured from Mouse Spinal Cord." Thesis, University of North Texas, 1992. https://digital.library.unt.edu/ark:/67531/metadc500431/.
Повний текст джерелаBricker, Rebecca L. "Q-VE-OPh, a control caspase inhibitor for analyzing neuronal death." Wright State University / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=wright1340647107.
Повний текст джерела