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Статті в журналах з теми "In vitro release kinetic models"
Costa, André Lima de Oliveira, Paula Cristina Rezende Enéas, Tiago Assis Miranda, Sueli Aparecida Mingoti, Cristina Duarte Vianna Soares, and Gerson Antônio Pianetti. "In vitro dissolution kinetic for mycophenolic acid derivatives tablets." Brazilian Journal of Pharmaceutical Sciences 49, no. 2 (June 2013): 311–19. http://dx.doi.org/10.1590/s1984-82502013000200013.
Повний текст джерелаQuintal Martínez, Juan Pablo, Jorge Carlos Ruiz Ruiz, and Maira Rubí Segura Campos. "Release Kinetic Studies of Stevia rebaudiana Extract Capsules from Sodium Alginate and Inulin by Ionotropic Gelation." Advances in Materials Science and Engineering 2018 (July 11, 2018): 1–8. http://dx.doi.org/10.1155/2018/6354924.
Повний текст джерелаKumar, B., and G. Jeyabalan. "Development of Anti-diabetic Niosomes Formulation Containing Metformin and Gliclazide." Indian Journal of Pharmaceutical and Biological Research 5, no. 02 (June 30, 2017): 24–28. http://dx.doi.org/10.30750/ijpbr.5.2.5.
Повний текст джерелаDewan, Irin, Md Maynul Islam, Maksud Al-Hasan, Joydeb Nath, Sefat Sultana, and Md Sohel Rana. "Surface Deposition and Coalescence and Coacervation Phase Separation Methods: In Vitro Study and Compatibility Analysis of Eudragit RS30D, Eudragit RL30D, and Carbopol-PLA Loaded Metronidazole Microspheres." Journal of Pharmaceutics 2015 (November 16, 2015): 1–10. http://dx.doi.org/10.1155/2015/254930.
Повний текст джерелаHurtado, M. González, J. Rieumont Briones, Laura M. Castro González, E. Ortiz Islas, and Inti Zumeta Dube. "Kinetic studies of the release profiles of antiepileptic drug released from a nanostructured TiO2 matrix." JOURNAL OF ADVANCES IN CHEMISTRY 12, no. 4 (December 16, 2016): 4365–73. http://dx.doi.org/10.24297/jac.v12i4.2176.
Повний текст джерелаIovanov, Rareș Iuliu, Ioan Tomuță, and Sorin Emilian Leucuța. "Development of a reservoir type prolonged release system with felodipine via simplex methodology." Medicine and Pharmacy Reports 89, no. 1 (September 28, 2015): 128–36. http://dx.doi.org/10.15386/cjmed-526.
Повний текст джерелаGönüllü, Ü., P. Gürpınar, and M. Üner. "Double-layer Tablets of Lornoxicam: Validation of Quantification Method, In vitro Dissolution and Kinetic Modelling." Tropical Journal of Pharmaceutical Research 14, no. 9 (October 12, 2015): 1659–66. http://dx.doi.org/10.4314/tjpr.v14i9.16.
Повний текст джерелаHaroun, Ahmed, Ali Osman, Sayed Ahmed та Ahmed H. Elghandour. "Synthesis and Characterization of Ibuprofen Delivery System Based on β-cyclodextrin/Itaconic Acid Copolymer". Trends in Sciences 19, № 19 (31 серпня 2022): 5825. http://dx.doi.org/10.48048/tis.2022.5825.
Повний текст джерелаKhalid, Ikrima, Mahmood Ahmad, Muhammad Usman Minhas, and Muhammad Sohail. "Formulation and in vitro evaluation of mucoadhesive controlled release matrix tablets of flurbiprofen using response surface methodology." Brazilian Journal of Pharmaceutical Sciences 50, no. 3 (September 2014): 493–504. http://dx.doi.org/10.1590/s1984-82502014000300007.
Повний текст джерелаNarissara Kulpreechanan and Feuangthit Niyamissara Sorasitthiyanukarn. "Evaluation of in vitro release kinetics of Capsaicin-loaded chitosan nanoparticles using DDSolver." International Journal of Research in Pharmaceutical Sciences 11, no. 3 (July 31, 2020): 4555–59. http://dx.doi.org/10.26452/ijrps.v11i3.2685.
Повний текст джерелаДисертації з теми "In vitro release kinetic models"
KOCERGINSKY, Patrícia de Oliveira. "Criptococose e determinação do efeito antifúngico in vitro e in vivo por sistema de liberação controlada com ciclopirox olamina." Universidade Federal de Pernambuco, 2013. https://repositorio.ufpe.br/handle/123456789/18294.
Повний текст джерелаMade available in DSpace on 2017-02-13T13:18:57Z (GMT). No. of bitstreams: 2 license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5) TESE colação de grau.pdf: 1971286 bytes, checksum: 680d0e24d2f0efbe0313ab8752f1cc93 (MD5) Previous issue date: 2013-02-22
CNPq
A criptococose é uma infecção fúngica predominantemente oportunista cujos principais agentes etiológicos são Cryptococcus neoformans e C. gattii. O tratamento de escolha para a micose é a anfotericina B associada ou não a 5-fluorocitosina seguido de terapia de manutenção com fluconazol. Contudo, falhas no tratamento associadas à toxicidade e ao aparecimento de resistência aos fármacos têm sido relatadas, o que torna essencial a descoberta de novas alternativas terapêuticas, como a ciclopirox olamina (CPO). Neste contexto, o objetivo deste estudo foi caracterizar e avaliar a ação in vitro e in vivo da CPO livre e encapsulada em lipossomas frente a amostras de Cryptococcus neoformans para futura aplicação no tratamento da criptococose sistêmica. Foram obtidas 30 amostras de Cryptococcus neoformans provenientes de pacientes imunocomprometidos. A preparação dos lipossomas convencionais e furtivos de CPO foi realizada pelo método da hidratação do filme lipídico e a caracterização foi realizada avaliando os seguintes parâmetros: tamanho de partícula, Índice de Polidispersão (PDI) e taxa de encapsulação (EE%). Para otimização dos constituintes lipídicos, foi realizado um planejamento fatorial fracionado a 24-1 a partir da melhor formulação obtida nos estudos de pré-formulação. A cinética de liberação in vitro foi conduzida para avaliar e comparar estatisticamente o perfil de liberação dos sistemas convencional e furtivo. Adicionalmente, testes de susceptibilidade antifúngica foram realizados de acordo com Clinical and Laboratotry Standards Institute (CLSI). Para caracterização molecular dos isolados, PCR fingerprinting foi conduzida utilizando os primers M13 e URA5. O estudo in vivo foi conduzido com camundongos imunossuprimidos, infectados com Cryptococcus neoformans (106 cels/mL) e tratados com CPO lipossomal (Lipo-CPO) (0.5 mg/Kg). As concentrações de CPO utilizadas na forma livre e encapsuladas em lipossomas convencionais e furtivos variaram de 0,30 a 625 µg/mL. Os resultados do planejamento fatorial mostraram que o ponto central apresentou características proeminentes com redução do tamanho de partícula em 17,1%; melhora do PDI em 15,34% e da quantidade de fármaco encapsulado (25%). A cinética do lipossoma furtivo apresentou uma velocidade de liberação mais controlada quando comparada ao lipossoma convencional. Com relação ao teste de susceptibilidade, todos os inóculos foram susceptíveis a CPO livre, com atividade fungistática entre 0,30 e 0,61 g/mL e fungicida entre 1,22 e 4,88 g/mL. Não houve diferença relacionada à atividade antifúngica entre as formulações lipossomais convencionais e furtivas. A atividade fungistática dos lipossomas foi observada em concentrações variando de 1,22 e 2,44 g/mL. A faixa das concentrações fungicidas foi de 1,22 a 9,76 g/mL. O padrão de bandas do URA5 revelou que todos os isolados apresentam genótipo VNI, característico de C. neoformans. Lipo-CPO apresentou eficácia antifúngica comparada à anfotericina B após 14 dias de infecção, reduzindo a carga fúngica em aproximadamente 8% no baço, 41% no fígado, 63% no pulmão e 89% no cérebro. O exame histológico evidenciou infiltrado celular no fígado dos grupos tratados com Lipo-CPO e anfotericina B, porém com menor intensidade quando comparado ao grupo controle. O estudo sugere que a CPO encapsulada em lipossomas apresenta significativa ação antimicótica frente às amostras sistêmicas de C. neoformans, reforçando seu potencial na terapêutica da criptococose.
Cryptococcosis is an opportunistic fungal infection whose the main ethiological agents are Cryptococcus neoformans and C. gattii. The treatment of choice for this mycosis is amphotericin B combined or not with 5-fluorocytosine, followed by maintenance therapy with fluconazole. However treatment failures associated with toxicity and drug resistance has been reported, which makes it essential to the discovery of new therapies, such as ciclopirox olamine (CPO). The purpose of this study was to characterize and evaluate the in vitro and in vivo antifungal activity of ciclopirox olamine in its free form and encapsulated in liposomes against thirty Cryptococcus neoformans isolates obtained from immunocompromised patients for future application in systemic cryptococcosis treatment. Preparation of conventional and stealth liposomes was performed to define particle size, polydispersity index (PDI), CPO amount of encapsulated and efficiency of encapsulation (EE%). For optimization of liposomal lipid constituents, a 24-1 fractional factorial design was carried out from the prominent formulation obtained in pre-characterization studies. In vitro release kinetics was conducted to evaluate and compare statistically the release profile of conventional and stealth liposomes. Antifungal susceptibility testing was conducted in accordance with the reference method. Regarding molecular characterization, PCR fingerprinting was carried out by using MT3 and URA5 primers. Concentrations of CPO used in free form and encapsulated into stealth and conventional liposomes ranged from 625 to 0.3 g.mL-1. Despite of the central point of the factorial design have increased the total lipids amount in 35.52%, it showed prominent characteristics when compared with the L4 formulation with improvement of the mean size in 17.1%, PDI in 15.34% and CPO amount in 25%. The minimum concentrations of stearylamine to obtain the stable formulation for one month was 5.88 mM. . Kinetics of stealth liposomes showed a release profile more controlled as compared to conventional liposomes. All inoculations were susceptible to CPO in its free form, presenting fungistatic activity between 0.3 and 0.61 g.mL-1 and fungicidal activity between 1.22 and 4.88 g.mL-1. There was no difference with respect to antimycotic activity between conventional and stealth liposomal formulations. Fungistatic activity of liposomes was observed at concentrations ranging from 1.22 and 2.44 g.mL-1. Fungicidal concentration range was 1.22-9.76 g.mL-1. The URA5 profile analized demonstrated all isolates are VNI genotype (C. neoformans). The treatment with Lipo-CPO showed a reduction of 8% of the C. neoformans population in spleen, 40.8% in liver, 63% in lungs and 89% in brain after 14 days of infection. Histological examination revealed cell infiltrate either Lipo-CPO or Amphotericin B treated groups, but less intense when compared to control group. The results suggest that Ciclopirox olamine loaded-liposomes have significant antimycotic activity against Cryptoccocus spp, reinforcing its potential for in vivo studies and its application in cryptococcosis treatment.
Syarifuddin, Adiansyah. "Multi sensory integration as a strategy to compensate for sodium and fat reduction in food." Thesis, Dijon, 2015. http://www.theses.fr/2015DIJOS088.
Повний текст джерелаIn recent years, health authorities worldwide advise for a reduction of salt and fat in daily food consumption. However, foods with reduced salt and fat content are often not appreciated by consumers, Therefore, the formulation of low-salt-fat foods that maintain acceptability is a major concern in food research. In this thesis, the multi-sensory integration and release kinetics of flavor compounds were explored as strategies to compensate for salt and fat reduction in cheese products (model cheeses and real cheeses). The objective was to better understand the mechanisms leading to aroma and salt release during mastication and to evaluate how the matrix composition and structure influence salt and aroma release profile.Multisensory integration approach to compensate for salt and fat reduction was studied in a first step. The structure and sensory perception of 24 cheese models varying in composition (2 levels of fat, 2 salt, 2 pH at renneting) and flavored with either a sardine aroma (associated to salt), a butter aroma (associated to fat) or not flavoured (control) were characterised by rheological measurements (uniaxial compression) and sensory evaluation (descriptive analysis). The results demonstrated an influence of the composition on the products structure and perceived texture. Furthermore, a significant saltiness enhancement was induced by sardine aroma while significant fat perception enhancement was induced by butter aroma. However, this influence of the aroma on other sensory dimensions depends on the texture of the products thus on their composition and structure. These results have been extended to real cheeses but with specificities. If the sardine flavor enhanced the perception of salt, only butter-sardine-flavor enhanced the perception of fat.In a second step, a physico-chemical approach was developed to explore the release kinetic of flavor compounds during in vitro breakdown using a chewing simulator. The aim was to use these data to explain the influence of the structure of model cheeses and real cheeses and their breakdown during chewing on sensory effects observed in the first step. Volatile compounds release was monitored by connecting the chewing simulator to a proton transfer reaction-mass spectrometry (PTR-MS), while salt release was monitored using a conductivity probe. Results showed that product composition and structure (fat, salt and pH at renneting) influenced aroma release, which however depends on the nature of the aroma: the more hydrophobic compounds are less sensitive to variations in fat content and more sensitive to variations in pH and therefore to the products structure. The salt release kinetic during in vitro chewing was also influenced by the composition and structure of the products. Indeed, beyond salt content which determined the amount of salt released, fat content and the pH at renneting modulated the release kinetic. In conclusion, this work showed a significant impact of the flavor compounds release kinetic and probably of temporality of sensations on the overall perception of salt and fat when consuming a complex food
Marcheix, Pierre-Sylvain. "Evaluation in vitro et in vivo d’un polymère biorésorbable à la Gentamycine dans le traitement expérimental d’infections ostéo-articulaires." Thesis, Limoges, 2016. http://www.theses.fr/2016LIMO0079/document.
Повний текст джерелаThe treatment of soft-tissue infections, osteomyelitis, and acute or chronic septic arthritis is a lengthy process that involves repeated surgical procedures and the systemic administration of antibiotics for at least 6 weeks to 3 months. Poor diffusion of antibiotics into bones and joints requires high doses given parenterally for long periods. At present, the antibiotic vector most widely used in humans with bone or joint infections is polymethylmethacrylate. Because PMMA is not bioabsorbable, multiple surgical procedures are required to eradicate infection. Furthermore, PMMA does not release its full antibiotic load over time and may yield local antibiotic concentrations lower than the minimal inhibitory concentration of the causative organism, thereby promoting the emergence of resistant strains. The objective of our work was to develop a fully bioabsorbable polymer capable of ensuring the prolonged and efficient release of its antibiotic load, thus improving the management of bone and joint infections. The specifications for the polymer included the release by the matrix system of 1-2 mg of gentamicin per day and per gram of mixture over more than 10 days. Other specifications were appropriate physical characteristics, a drug release rate sufficient to ensure optimal treatment safety, and ease of implantation. The polymer was also to be bioabsorbable, i.e., subject to degradation into fragments capable of being eliminated naturally by the body. High-molecular weight PLA50P, Poly(D,L-lactic acid) was created and found to meet these specifications. Use of this polymer as large particles (0.5 to 1 mm) limited the initial burst phenomenon. A gentamicin-PLA50P mixture was obtained by compression of the two components prepared in powder form. The antibiotic load was set at 20% to limit the initial burst. The polymer can be sterilized by gamma irradiation, which has no effect on drug release characteristics.In vitro kinetic studies of gentamicin release by the polymer showed a peak on day 12 followed by a plateau that lasted until day 63. After 3 weeks, the cumulative amount of gentamicin released in vitro was 54% of the total amount loaded onto the polymer. In vivo gentamicin concentrations measured in situ were 5.1 µg/mL on day 3, 1.9 µg/mL on day 7, and 0 µg/mL on day 35, when the polymer was no longer visible to the naked eye. Thus, both in vivo and in vitro, gentamicin was released in concentrations greater than the MIC of the microorganism, for longer than 3 weeks.To test the gentamicin-loaded polymer, we created a rat model of periosteal infection. Rats aged 10-12 weeks received two 100 mL injections of methicillin-susceptible Staphylococcus aureus collected from animals, into the middle third of the hind leg, in contact with the bone. Treatment with gentamicin-loaded PLA50P proved superior over parenteral administration of an equivalent gentamicin dose, consistently reverting the bacteriological cultures to negative. We then created a rabbit model of septic arthritis. A doe weighing 4 kg received an add intraarticular injection of 1 mL of a solution containing 103 cfu/mL of a methicillin-sensitive S. aureus strain collected from another rabbit. Gentamicin-loaded PLA50P treatment induced a highly significant drop in the intraarticular bacterial load (by 3-4 log10), whereas standard systemic gentamicin therapy failed to significantly diminish bacterial counts comparatively to the untreated controls. Thus, gentamicin-loaded PLA50P diminished the bacterial load by 3 log10 comparatively to the other groups and allowed eradication of the infection in 2 of the 6 rabbits.In sum, gentamicin-loaded PLA50P (i) ensures the stability of the antibiotic; (ii) is available as a stable powder; (iii) ensures the prolonged release of gentamicin over several weeks; (iv) produces a limited burst effect; (v) exhibits very good biotolerance; (vi) and is more effective than standard antimicrobial therapy
Stolberg-Stolberg, Josef Verfasser], Rainer H. H. [Akademischer Betreuer] Burgkart, Andreas K. [Akademischer Betreuer] Nüssler, and Andreas B. [Akademischer Betreuer] [Imhoff. "Effects of Cartilage Impact with and without Fracture on Chondrocyte Viability and the Release of Inflammatory Markers in Two In vitro Models / Josef Stolberg-Stolberg. Gutachter: Andreas K. Nüssler ; Andreas Imhoff ; Rainer H. H. Burgkart. Betreuer: Rainer H. H. Burgkart." München : Universitätsbibliothek der TU München, 2014. http://d-nb.info/1064976158/34.
Повний текст джерелаBillanou, Ian. "Modélisation expérimentale et théorique pour la quantification du débit sanguin par Tomographie à Emission de Positrons." Thesis, Toulouse, INPT, 2010. http://www.theses.fr/2010INPT0006/document.
Повний текст джерелаPositron Emission Tomography (PET) provides a dynamic and space-resolved measurement of the concentration field of a radioactive tracer previously injected to the patient. Quantification of cerebral blood flow by PET is based on the use of a kinetic model linking cerebral blood flow to the spatial and temporal variations of tracer concentration in the brain. Various kinetic models have been proposed in the literature. However, most of the mare based on a compartmental approach of the observed organ In this case, the organ is divided in two compartments, the capillary and the tissue, and the exchanges between these two compartments are often described by a first order kinetic model. Results obtained with this kind of model under estimate the flow rate and are notable to predict the first instants of the tracer dynamics distribution. With the continuous improvement of the temporal resolution of PET, these weaknesses have been confirmed, which led to the development of models incorporating more physiological reality. However, all these models have been developed to describe exchanges between micro-circulation and surrounding tissue at the scale of capillary vessels (microscopic scale). Because the spatial resolution of PET inclinical practice is insufficient to allow the distinction between micro-circulation and tissue, using of these models with kinetic measurement of macroscopic concentrations exceeds their theoretical validity and can introduce false results. In this context, we propose a kinetic model based on up-scaling (using the method of volume averaging). This up-scaling technique allows to replace the two previous compartments (tissue and micro-circulation) by an homogeneous fictive volume, whose macroscopic properties are calculated from the microscopic properties of are presentative elementary volume (REV) of the medium. First, in order to compare the results of this model with those of the standard compartmental model, the considered REV consists of a single capillary and its surrounding tissue. Second, additional geometric complexity is introduced by considering an isotropic capillary network at the Darcy scale. These models are used to identify the flow rate using an inverse method. For that purpose, the temporal evolution of concentration field in a geometry of reference, which can't be measured by PET due to its low spatial resolution, is determined by numerical simulations and by in vitro measurements. These measurements are performed using an experimental model developed during this work to reproduce the flow in a channel passing through a diffusive matrix (alginate gel)
Kuznetsova, Alena. "Layered Double Hydroxides (LDH) as versatile nanoreservoirs for application in multi-functional coatings." Doctoral thesis, 2020. http://hdl.handle.net/10773/30586.
Повний текст джерелаO objetivo do presente trabalho consistiu na síntese e caracterização de nanoreservatórios inorgânicos baseados em hidróxidos duplos lamelares (HDL) com diferentes espécies ativas imobilizadas, nomeadamente inibidores de corrosão e indicadores de pH. Uma das características mais relevantes associada com o HDL é a sua capacidade de permuta aniónica. Apesar dos inúmeros trabalhos que descrevem a utilização do HDL para aplicações em revestimentos protetores contra a corrosão, o estudo relacionado com a imobilização e consequente libertação das espécies aniónicas é algo limitado. Além disso, não existem estudos sistemáticos na literatura que correlacionem a estrutura dos nanocontentores com as propriedades (perfis e condições de libertação controlada) e o efeito correspondente nos revestimentos. Neste trabalho, várias metodologias foram aplicadas para a preparação dos HDL. A estrutura, morfologia, propriedades coloidais e texturais dos nanocontentores resultantes foram caracterizadas por difração de raios-X (DRX), espectroscopia no infravermelho por transformada de Fourier (FTIR), microscopia eletrónica de varrimento (SEM), dispersão dinâmica de luz (DLS), análise termogravimétrica (TG) e isotérmicas de adsorção-desadsorção de azoto. Atenção especial foi prestada aos estudos de libertação de diferentes espécies ativas imobilizadas em HDL, nomeadamente as condições experimentais que podem levar à libertação das espécies ativas (ex.: pH, presença de sais), estabelecimento de modelos cinéticos e definição de mecanismos de libertação, recorrendo à espetrofotometria de UV-Visível. Além disso, o processo de adsorção de espécies ativas foi investigado para tentar perceber o que ocorre durante a síntese de diferentes composições de HDL bem como avaliar o impacto na aplicação prática de nanoreservatórios em revestimentos multifuncionais. Os resultados obtidos permitem concluir que, de forma geral, a libertação de espécies ativas é determinada pela difusão, com possibilidade de reação de permuta aniónica, quando espécies aniónicas estão presentes no ambiente. No entanto, os perfis de libertação, extensão da mesma e adsorção de espécies ativas em HDL dependem do método de síntese, bem como da estrutura e propriedades das espécies ativas. Igualmente relevante, é que as diferentes composições de HDL apresentam capacidade de libertar as espécies ativas imobilizadas em resposta à presença de aniões na solução (ex.: cloretos, hidróxidos, carbonatos), mesmo quando não intercaladas nas galerias do HDL, encontrando-se apenas adsorvidas na superfície externa do HDL. Além disso, a tendência dos materiais de HDL à dissolução ou reação sob condições extremas de pH, em combinação com alterações nas propriedades da superfície, tem influência no maior ou menor grau de aglomeração e/ou agregação das partículas, podendo afetar a adsorção e libertação das diferentes espécies. Atendendo às propriedades dos materiais obtidos, concluiu-se que vários HDL estudados são candidatos promissores para aplicação em revestimentos multifuncionais. Para além disso o presente trabalho pode ser usado como suporte na elaboração e validação de modelos computacionais que visam prever a captação e libertação de espécies ativas do HDL.
III Quadro Comunitário de Apoio
Programa Doutoral em Ciência e Engenharia de Materiais
Частини книг з теми "In vitro release kinetic models"
Zhang, Bin, Haiteng Li, Shaokang Wang, Shahid Ahmed Junejo, Xingxun Liu, and Qiang Huang. "In Vitro Starch Digestion: Mechanisms and Kinetic Models." In Starch Structure, Functionality and Application in Foods, 151–67. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-0622-2_9.
Повний текст джерелаBuckley, Stephen T., Kwang-Jin Kim, and Carsten Ehrhardt. "In Vitro Cell Culture Models for Evaluating Controlled Release Pulmonary Drug Delivery." In Controlled Pulmonary Drug Delivery, 417–42. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-9745-6_18.
Повний текст джерелаThorburn, Christine E., and Brian Slocombe. "The Use of In-Vitro Kinetic Models in the Evaluation of β-Lactam/β-Lactamase Inhibitor Combinations." In Advances in Experimental Medicine and Biology, 157–62. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4757-9206-5_16.
Повний текст джерелаOwuor, James Jorum, Florence Oloo, Japheth Kibet Ngetich, Mwaiwa Kivunzya, Wesley Nyaigoti Omwoyo, and Jeremiah Waweru Gathirwa. "Comparison of Freeze and Spray Drying to Obtain Primaquine-Loaded Solid Lipid Nanoparticles." In Research Anthology on Synthesis, Characterization, and Applications of Nanomaterials, 288–304. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-8591-7.ch012.
Повний текст джерелаSinghal, Peeush, Rajneesh Dutt Kaushik, and Vijay Jyoti Kumar. "Preparation and in vitro Characterisation of Solid Dispersion Floating Tablet by Effervescent Control Release Technique with Improved Floating Capabilities." In Molecular Pharmacology. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92187.
Повний текст джерелаBin Zafar Auniq, Reedwan, Namon Hirun, and Upsorn Boonyang. "Three-Dimensionally Ordered Macroporous-Mesoporous Bioactive Glass Ceramics for Drug Delivery Capacity and Evaluation of Drug Release." In Ceramic Materials [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.95290.
Повний текст джерелаSteensma, Aukje, Marcel J. B. Mengelers, Hub P. J. M. Noteborn, and Harry A. Kuiper. "Kinetic Models Describing In vitro Transport and Metabolism of Isoflavones and Their Glycosides in Human Caco-2 Cells." In Dietary Anticarcinogens and Antimutagens, 58–63. Elsevier, 2000. http://dx.doi.org/10.1533/9781845698188.2.58.
Повний текст джерелаDrofenik, Mihael. "Thermodynamic Aspects of Homeopathy." In Alternative Medicine [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94148.
Повний текст джерелаGárate-Vélez, Lorena, Claudia Escudero-Lourdes, Daniela Salado-Leza, Armando González-Sánchez, Ildemar Alvarado-Morales, Daniel Bahena, Gladis Judith Labrada-Delgado, and José Luis Rodríguez-López. "Anthropogenic Iron Oxide Nanoparticles Induce Damage to Brain Microvascular Endothelial Cells Forming the Blood-Brain Barrier." In Advances in Alzheimer’s Disease. IOS Press, 2021. http://dx.doi.org/10.3233/aiad210010.
Повний текст джерелаТези доповідей конференцій з теми "In vitro release kinetic models"
Blanco, Elvin, Takafumi Sangai, Funda Meric-Bernstam, and Mauro Ferrari. "Chemotherapeutic Synergy Enhancement Through Micellar Nanotherapeutics." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13263.
Повний текст джерелаMendygarin, Yertay, Luis R. Rojas-Solórzano, Nurassyl Kussaiyn, Rakhim Supiyev, and Mansur Zhussupbekov. "Eulerian-Eulerian Multiphase Modeling of Blood Cells Segregation in Flow Through Microtubes." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-70850.
Повний текст джерелаBerchane, Nader S., Kenneth H. Carson, Allison C. Rice-Ficht, and Malcolm J. Andrews. "Investigation of Drug Release From Biodegradable PLG Microspheres: Experiment and Theory." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176030.
Повний текст джерелаSom, S., Z. Wang, W. Liu, and D. E. Longman. "Comparison of Different Chemical Kinetic Models for Biodiesel Combustion." In ASME 2013 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/icef2013-19094.
Повний текст джерелаKluge, Jonathan A., Rudra A. Pampati, Mara L. Schenker, Daniel J. Zhou, John E. Esterhai, David L. Kaplan, and Robert L. Mauck. "Delivery of Active FGF-2 From Mechanically-Stable Biological Nanofibers Accelerates Cell Ingress Into Multifiber Composites." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53955.
Повний текст джерелаBass, Joseph L., and Eric P. Fahrenthold. "A Kinetic Formulation of Reacting Molecular Dynamics." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65451.
Повний текст джерелаZhou, Apeng, Shirin Jouzdani, and Ben Akih-Kumgeh. "Reduced Chemical Kinetic Models of C1 - C4 Alcohols Using the Alternate Species Elimination Approach." In ASME 2019 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/icef2019-7114.
Повний текст джерелаBanerjee, Siddhartha, Nidheesh Bharadwaj, and Christopher J. Rutland. "Investigation of In-Cylinder Mixing Using Large Eddy Simulation Models for LTC Diesel Applications." In ASME 2009 Internal Combustion Engine Division Spring Technical Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/ices2009-76031.
Повний текст джерелаNontasirichayakul, Chanicha, Chutima Wiranidchapong, Worapan Sithithaworn, and Duangratana Shuwisitkul. "Optimization of Formulation Variables Using Central Composite Design to Enhance Andrographolide Release from <i>Andrographis paniculata</i> Extract-Chitosan Solid Dispersion." In 5th International Conference and Exhibition on Pharmaceutical Sciences and Technology 2022. Switzerland: Trans Tech Publications Ltd, 2022. http://dx.doi.org/10.4028/p-3xj8r7.
Повний текст джерелаJen, Chun-Ping, and Neng-Chuan Tien. "Investigation of Colloid-Facilitated Effects on the Radionuclides Migration in the Fractured Rock With a Kinetic Solubility-Limited Dissolution Model." In ASME 2010 13th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2010. http://dx.doi.org/10.1115/icem2010-40001.
Повний текст джерелаЗвіти організацій з теми "In vitro release kinetic models"
Spiers, Donald, Arieh Gertler, Harold Johnson, and James Spain. An In Vitro and In Vivo Investigation of the Diverse Biological Activities of Bovine Placental Lactogen. United States Department of Agriculture, August 1993. http://dx.doi.org/10.32747/1993.7568087.bard.
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