Добірка наукової літератури з теми "Iminoquinone"

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Статті в журналах з теми "Iminoquinone"

1

Dong, Yu, Zhong-Hui Li, Bing He, Hui Jiang, Xiang-Long Chen, Ji-Xian Ye, Qiang Zhou, Long-Sen Gao, Qi-Qi Luo, and Zhi-Chuan Shi. "Silver-Catalyzed One-Pot Biarylamination of Quinones with Arylamines: Access to N-Arylamine-Functionalized p-Iminoquinone Derivatives." Synthesis 54, no. 09 (February 7, 2022): 2242–50. http://dx.doi.org/10.1055/s-0041-1737340.

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AbstractConcise one-pot biarylamination of quinones with arylamines was developed to synthesize N-arylamine-functionalized p-iminoquinones derivatives. The approach employed AgOAc as the catalyst and (NH4)2S2O8 as the oxidant in the presence of 3-chlorophenylboronic acid, giving a series of N-arylamine-functionalized p-iminoquinone derivatives in moderate to good yields whereas reaction in the absence of the 3-chlorophenylboronic acid, gave a series of N-arylamine-functionalized 1,4-naphthoquinone derivatives. This catalytic approach represents a step-economic and convenient strategy for the difunctionalization of quinones.
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2

Bouchard, Luc, Ian Marcotte, Jean Marc Chapuzet, and Jean Lessard. "Electroreduction of 1-methyl 5-nitroindole, 5-nitrobenzofurane, and 5-nitrobenzothiophene in acidic and basic hydroorganic media: Generation and trapping of iminoquinone-type intermediates and electrosynthesis of ring-substituted amino derivatives." Canadian Journal of Chemistry 81, no. 10 (October 1, 2003): 1108–18. http://dx.doi.org/10.1139/v03-149.

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Preparative electrolysis of 1-methyl-5-nitroindole (1b, X = NCH3), 5-nitrobenzofurane (1c, X = O), and 5-nitrobenzothiophene (1d, X = S) at Hg, in acidic hydromethanolic media, leads to the formation of the corresponding 4-substituted amino derivatives 5, which result from the 100% regioselective addition to iminoquinone-type intermediate 4 of methanol or of any other good nucleophile present in the electrolytic solution. In acidic medium, the iminoquinonium intermediates 4b and 4c were trapped in a cycloaddition reaction with cyclopentadiene added to the electrolysis medium. The regiochemistry of the nucleophilic addition is discussed in light of AM1 calculations. Key words: 1-methyl-5-nitroindole, 5-nitrobenzofurane, 5-nitrobenzothiophene, iminoquinone, electrosynthesis.
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3

Klementyeva, Svetlana V., Anton N. Lukoyanov, Mikhail Yu Afonin, Max Mörtel, Anton I. Smolentsev, Pavel A. Abramov, Alyona A. Starikova, Marat M. Khusniyarov, and Sergey N. Konchenko. "Europium and ytterbium complexes with o-iminoquinonato ligands: synthesis, structure, and magnetic behavior." Dalton Transactions 48, no. 10 (2019): 3338–48. http://dx.doi.org/10.1039/c8dt04849e.

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4

Chandrasekar, Selvaraj, and Govidasamy Sekar. "An efficient synthesis of iminoquinones by a chemoselective domino ortho-hydroxylation/oxidation/imidation sequence of 2-aminoaryl ketones." Organic & Biomolecular Chemistry 14, no. 11 (2016): 3053–60. http://dx.doi.org/10.1039/c5ob02659h.

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5

Bamford, Karlee L., Lauren E. Longobardi, Lei Liu, Stefan Grimme та Douglas W. Stephan. "FLP reduction and hydroboration of phenanthrene o-iminoquinones and α-diimines". Dalton Transactions 46, № 16 (2017): 5308–19. http://dx.doi.org/10.1039/c7dt01024a.

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Hydrogenation and hydroboration of an N-aryl-phenanthrene-o-iminoquinone and two N,N′-diaryl-phenanthrene α-diimines give a series of derivatives including 1,3,2-oxaza- and diazaboroles and borocyclic radicals.
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6

Kamitanaka, Tohru, Koji Morimoto, Toshifumi Dohi, and Yasuyuki Kita. "Controlled-Coupling of Quinone Monoacetals by New Activation Methods: Regioselective Synthesis of Phenol-Derived Compounds." Synlett 30, no. 10 (March 25, 2019): 1125–43. http://dx.doi.org/10.1055/s-0037-1611735.

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We have studied for a long time the reaction of quinone acetal type compounds, such as quinone monoacetals, quinone O,S-acetals, and iminoquinone monoacetals, and have reported the regioselective introduction of various nucleophiles. Quinone monoacetals show various types of reactivities toward nucleophiles due to their unique structures. In this study, we found that aromatic and alkene nucleophiles can be regioselectively introduced into the α-position of the carbonyl group on quinone monoacetals by specific activation of the acetal moiety. These reactions enabled the metal-free synthesis of highly functionalized aromatic compounds by the regioselective introduction of nucleophiles. In this account, we describe our recent studies of the coupling of quinone monoacetals.1 Introduction2 Regioselective Introduction of Aromatic Nucleophiles into α-Position of Carbonyl2.1 Biaryl Synthesis by Introduction of Aromatic Nucleophiles2.2 Synthesis of Terphenyls and Oligoarenes by Iterative Coupling2.3 Synthesis of Phenol Cross-Coupling Products3 [3+2] Coupling with Alkene Nucleophiles3.1 Development of Efficient [3+2] Coupling3.2 Improvement of Brønsted Acid Promotor4 Synthesis of α-Aryl Carbonyl Compounds Triggered by Silyl Transfer5 Utilization of o-Quinone Monoacetals6 Application to Iminoquinone Monoacetals7 Conclusion
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7

Conboy, Darren, and Fawaz Aldabbagh. "6-Imino-1,2,3,4,8,9,10,11-octahydropyrido[1,2-a]pyrido[1′,2′:1,2]imidazo[4,5-f]benzimidazole-13-one: Synthesis and Cytotoxicity Evaluation." Molbank 2020, no. 1 (March 5, 2020): M1118. http://dx.doi.org/10.3390/m1118.

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The first report of an iminoquinone of imidazo[4,5-f]benzimidazole is described. The 2D-NOESY spectrum of 1,2,3,4,8,9,10,11-octahydropyrido[1,2-a]pyrido[1’,2’:1,2]imidazo[4,5-f]benzimidazol-6-amine was used to confirm the location of the imine moiety at the C-6 position of the title compound. Cytotoxicity data from the National Cancer Institute are included.
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8

Johannissen, Linus O., Nigel S. Scrutton, and Michael J. Sutcliffe. "The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer." Journal of The Royal Society Interface 5, suppl_3 (May 21, 2008): 225–32. http://dx.doi.org/10.1098/rsif.2008.0068.focus.

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The role of promoting vibrations in enzymic reactions involving hydrogen tunnelling is contentious. While models incorporating such promoting vibrations have successfully reproduced and explained experimental observations, it has also been argued that such vibrations are not part of the catalytic effect. In this study, we have employed combined quantum mechanical/molecular mechanical methods with molecular dynamics and potential energy surface calculations to investigate how enzyme and substrate motion affects the energy barrier to proton transfer for the rate-limiting H-transfer step in aromatic amine dehydrogenase (AADH) with tryptamine as substrate. In particular, the conformation of the iminoquinone adduct induced by AADH was found to be essential for a promoting vibration identified previously—this lowers significantly the ‘effective’ potential energy barrier, that is the barrier which remains to be surmounted following collective, thermally equilibrated motion attaining a quantum degenerate state of reactants and products. When the substrate adopts a conformation similar to that in the free iminoquinone, this barrier was found to increase markedly. This is consistent with AADH facilitating the H-transfer event by holding the substrate in a conformation that induces a promoting vibration.
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9

Liu, Liu, Kun Chen, Wen-Zhen Wu, Peng-Fei Wang, Hang-Yu Song, Hongbin Sun, Xiaoan Wen, and Qing-Long Xu. "Organocatalytic Para-Selective Amination of Phenols with Iminoquinone Monoacetals." Organic Letters 19, no. 14 (July 11, 2017): 3823–26. http://dx.doi.org/10.1021/acs.orglett.7b01700.

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10

Ershova, I. V., and A. V. Piskunov. "Complexes of Group III Metals based on o-Iminoquinone Ligands." Russian Journal of Coordination Chemistry 46, no. 3 (March 2020): 154–77. http://dx.doi.org/10.1134/s1070328420030021.

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Дисертації з теми "Iminoquinone"

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Ju, Changqing. "Reactive iminoquinone metabolites of indomethacin and carbamazepine, implications for drug-induced idiosyncratic reactions." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0007/NQ41183.pdf.

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2

Lai, Weidong George. "Bioactivation of trimethoprim, fluperlapine and nevirapine, roles of iminoquinone-type Michael acceptors in idiosyncratic drug reactions." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ49973.pdf.

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3

Das, Hari Sankar [Verfasser], and Biprajit [Akademischer Betreuer] Sarkar. "Ruthenium complexes with non-innocent quinonoid, quinoline-5,8-dione and iminoquinone ligands : synthesis, structure, redox properties and electron distribution / Hari Sankar Das. Betreuer: Biprajit Sarkar." Stuttgart : Universitätsbibliothek der Universität Stuttgart, 2012. http://d-nb.info/102604331X/34.

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4

(6629939), Ezra J. Coughlin. "Facilitating Multi-Electron Chemistry in the F-Block Using Iminoquinone Ligands." Thesis, 2019.

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The chemistry of the f-block is relatively unknown when compared to the rest of the periodic table. Transition metals and main group elements have enjoyed thorough study and development over the last 200 years, while many of the lanthanides and actinides weren’t even discovered until the 1940’s. This is troublesome, as knowledge of these elements is critical for environmental, industrial and technological advances. Understanding bonding motifs and reactivity pathways is fundamental to advancing the field of f-block chemistry. The use of redox- active ligands has aided in the construction of new bonding modes and discovery of new reaction pathways by providing electrons for these transformations. A particularly successful partnership is formed when redox-active ligands are combined with lanthanides, as these elements are usually considered redox-restricted. A series of lanthanide complexes featuring the iminoquinone ligand in three oxidation states will be discussed. The use of the ligands as a source of electrons for reactivity is also described, with new bonding motifs for lanthanides being realized. The iminoquinone ligand can also serve to break bonds. The uranyl (UO22+) ion is notoriously difficult to handle due to its strong U-O multiple bonds. To overcome this, we developed a series of uranyl complexes and studied the ability of the iminoquinone ligand to serve as an electron source for reduction of uranium, with concomitant U-O bond cleavage.

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Книги з теми "Iminoquinone"

1

Ju, Changqing. Reactive iminoquinone metabolites of indomethacin and carbamazepine: Implications for drug-induced idiosyncratic reactions. 1999.

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2

Lai, Weidong George. Bioactivation of trimethoprim, fluperlapine and nevirapine: roles of iminoquinine-type michael acceptors in idiosyncratic drug reactions. 2000.

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Частини книг з теми "Iminoquinone"

1

Marcotte, Ian, Jean Marc Chapuzet, Yves Dory, and Jean Lessard. "Iminoquinones as Electrogenerated Electrophilic Species." In Novel Trends in Electroorganic Synthesis, 65–68. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_18.

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