Дисертації з теми "Imaging in a neural tissue"
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Hui, Sai-kam, and 許世鑫. "Magnetic resonance diffusion tensor imaging for neural tissue characterization." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42841306.
Повний текст джерелаHui, Sai-kam. "Magnetic resonance diffusion tensor imaging for neural tissue characterization." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42841306.
Повний текст джерелаEppelheimer, Maggie S. "Identification of Chiari Malformation Type I Brain Morphology and Biomechanics: A Multi-Faceted Approach to Determine Diagnostic and Treatment Criteria." University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1595680107882868.
Повний текст джерелаMayerich, David Matthew. "Acquisition and reconstruction of brain tissue using knife-edge scanning microscopy." Texas A&M University, 2003. http://hdl.handle.net/1969.1/563.
Повний текст джерелаAbdeladim, Lamiae. "Large volume multicolor nonlinear microscopy of neural tissues." Thesis, Université Paris-Saclay (ComUE), 2018. http://www.theses.fr/2018SACLX070/document.
Повний текст джерелаMultiphoton microscopy has transformed neurobiology since the 1990s by enabling 3D imaging of thick tissues at subcellular resolution. However the depths provided by multiphoton microscopy are limited to a few hundreds of micrometers inside scattering tissues such as the brain. In the recent years, several strategies have emerged to overcome this depth limitation and to access larger volumes of tissue. Although these novel approaches are transforming brain imaging, they currently lack efficient multicolor and multicontrast modalities. This work aims at developing large-scale and deep-tissue multiphoton imaging modalities with augmented contrast capabilities. In a first chapter, we present the challenges of high-content large-volume brain imaging, with a particular emphasis on powerful multicolor labeling strategies which have so far been restricted to limited scales. We then introduce chromatic serial multiphoton (Chrom-SMP) microscopy, a method which combines automated histology with multicolor two-photon excitation through wavelength-mixing to access multiple nonlinear contrasts across large volumes, from several mm3 to whole brains, with submicron resolution and intrinsic channel registration. In a third chapter, we explore the potential of this novel approach to open novel experimental paradigms in neurobiological studies. In particular, we demonstrate multicolor volumetric histology of several mm3 of Brainbow-labeled tissues with preserved diffraction-limited resolution and illustrate the strengths of this method through color-based tridimensional analysis of astrocyte morphology, interactions and lineage in the mouse cerebral cortex. We further illustrate the potential of the method through multiplexed whole-brain mapping of axonal projections labeled with distinct tracers. Finally, we develop multimodal three-photon microscopy as a method to access larger depths in live settings
Channappa, Lakshmi [Verfasser], and Thomas [Akademischer Betreuer] Euler. "Electrical Imaging of Aberrant Activity in Neural Tissues Using High Density Microelectrode Arrays / Lakshmi Channappa ; Betreuer: Thomas Euler." Tübingen : Universitätsbibliothek Tübingen, 2016. http://d-nb.info/1199615544/34.
Повний текст джерелаRambani, Komal. "Thick brain slice cultures and a custom-fabricated multiphoton imaging system: progress towards development of a 3D hybrot model." Thesis, Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/22702.
Повний текст джерелаWellen, Jeremy W. "Characterization of soft-tissue response to mechanical loading using nuclear magnetic resonance (NMR) and functional magnetic resonance imaging (fMRI) of neuronal activity during sustained cognitive-stimulus paradigms." Link to electronic thesis, 2003. http://www.wpi.edu/Pubs/ETD/Available/etd-0430103-140128.
Повний текст джерелаBernal, Moyano Jose. "Deep learning for atrophy quantification in brain magnetic resonance imaging." Doctoral thesis, Universitat de Girona, 2020. http://hdl.handle.net/10803/671699.
Повний текст джерелаLa cuantificación de la atrofia cerebral es fundamental en la neuroinformática ya que permite diagnosticar enfermedades cerebrales, evaluar su progresión y determinar la eficacia de los nuevos tratamientos para contrarrestarlas. Sin embargo, éste sigue siendo un problema abierto y difícil, ya que el rendimiento de los métodos tradicionales depende de los protocolos y la calidad de las imágenes, los errores de armonización de los datos y las anomalías del cerebro. En esta tesis doctoral, cuestionamos si los métodos de aprendizaje profundo pueden ser utilizados para estimar mejor la atrofia cerebral a partir de imágenes de resonancia magnética. Nuestro trabajo muestra que el aprendizaje profundo puede conducir a un rendimiento de vanguardia en las evaluaciones transversales y competir y superar los métodos tradicionales de cuantificación de la atrofia longitudinal. Creemos que los métodos transversales y longitudinales propuestos pueden ser beneficiosos para la comunidad investigadora y clínica
Killich, Markus. "Tissue Doppler Imaging." Diss., lmu, 2007. http://nbn-resolving.de/urn:nbn:de:bvb:19-67089.
Повний текст джерелаEinarsdóttir, Hildur. "Imaging of soft tissue tumors /." Stockholm, 2003. http://diss.kib.ki.se/2003/91-7349-647-2/.
Повний текст джерелаSharma, Srikanta. "Microultrasound imaging of tissue dysplasia." Thesis, University of Dundee, 2015. https://discovery.dundee.ac.uk/en/studentTheses/ce30ac7f-8d18-464d-bbe5-5e9329ff5ff2.
Повний текст джерелаLee, Peter. "Scalable multi-parametric imaging of excitable tissue : cardiac imaging." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:a2594103-894b-4e1c-bdbb-43886f0d7fe0.
Повний текст джерелаKillich, Markus. "Tissue Doppler imaging Erstellung von Referenzwerten für tissue velocity imaging, strain und strain rate beim Hund /." [S.l.] : [s.n.], 2006. http://edoc.ub.uni-muenchen.de/archive/00006708.
Повний текст джерелаPoland, Simon. "Techniques in deep imaging within biological tissue." Thesis, University of Strathclyde, 2006. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21651.
Повний текст джерелаLapp, Sarah Julia. "Bioluminescence Imaging Strategies for Tissue Engineering Applications." Thesis, Virginia Tech, 2010. http://hdl.handle.net/10919/32338.
Повний текст джерелаMaster of Science
Unnersjö-Jess, David. "High-resolution imaging of kidney tissue samples." Licentiate thesis, KTH, Cellulär biofysik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-207577.
Повний текст джерелаQC 20170523
Sahalan, Mariaulpa. "Diffusion-weighted Imaging of Lymph Node Tissue." Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/20070.
Повний текст джерелаMartinini, Filippo. "Deep Neural Recovery For Compressed Imaging." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/22431/.
Повний текст джерелаFord-Dunn, Helen. "Genetic modification of neural tissue for xenotransplantation." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404117.
Повний текст джерелаStabenfeldt, Sarah Elizabeth. "Bioactive thermoresponsive hydrogels for neural tissue engineering." Diss., Atlanta, Ga. : Georgia Institute of Technology, 2007. http://hdl.handle.net/1853/26680.
Повний текст джерелаCommittee Chair: LaPlaca, Michelle; Committee Member: Bellamkonda, Ravi; Committee Member: Garcia, Andres; Committee Member: Hochman, Shawn; Committee Member: Wang, Yadong. Part of the SMARTech Electronic Thesis and Dissertation Collection.
Hoyt, Kenneth Leon Forsberg Flemming. "Spectral strain estimation techniques for tissue elasticity imaging /." Philadelphia, Pa. : Drexel University, 2005. http://dspace.library.drexel.edu/handle/1860/504.
Повний текст джерелаSikdar, Siddhartha. "Ultrasonic imaging of flow-induced vibrations in tissue /." Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/6100.
Повний текст джерелаHilton, Judy A. "An Acoustic Imaging System for Soft Tissue Stress." Fogler Library, University of Maine, 2005. http://www.library.umaine.edu/theses/pdf/HiltonJA2005.pdf.
Повний текст джерелаBálint, Péter Vince. "Ultrasound imaging in joint and soft tissue inflammation." Thesis, University of Glasgow, 2002. http://theses.gla.ac.uk/2266/.
Повний текст джерелаLi, Teng. "Advanced Photoacoustic Measurement and Imaging in Biological Tissue." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.506584.
Повний текст джерелаTillberg, Paul W. "Expansion microscopy : improving imaging through uniform tissue expansion." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106094.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (pages 70-76).
Until the past decade, optical microscopy of biological specimens was strongly limited by diffraction and scattering, affecting imaging resolution and depth, respectively. Now, numerous methods are available to overcome each of these limitations, but sub-diffraction limited resolution imaging over large volumes of scattering tissue is still a challenge. This work concerns the development of a new method, Expansion Microscopy (ExM) for achieving effect sub-diffraction-limited optical images in biological specimens. In ExM, the specimen is embedded in a swellable gel material to which fluorescent probes are chemically anchored. The embedded tissue is strongly digested so that it will not hinder uniform expansion driven by the gel. The gel with embedded, fragmented tissue is washed in water, triggering expansion of around 4-fold in each dimension. A variant of the method, ExM with Protein Retention (proExM) is presented that allows proteins themselves, rather than fluorescent probes, to be anchored by a small molecule cross-linker to the gel, so that the method may be carried out entirely with commercial components and standard antibodies.
by Paul W. Tillberg.
Ph. D.
Laurens, Ediuska V. "Imaging of Tyramine-Substituted Hydrogels for Tissue Replacement." Cleveland State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=csu1265639619.
Повний текст джерелаPenmatsa, Madhuri Krishna. "Infrared Spectral Imaging Analysis Of Cartilage Repair Tissue." Master's thesis, Temple University Libraries, 2011. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/124100.
Повний текст джерелаM.S.
Articular cartilage is a homogenous tissue that provides frictionless movement between joints while withstanding repetitive physical stress. Once degenerated as a result of osteoarthritis or an injury, it has very limited capacity for self-repair. Recent research has focused on developing many new technologies for cartilage repair. The successful application of these strategies is limited in part to lack of techniques to evaluate tissue response to interventions. Assessment of the structural and molecular changes in the primary cartilage components, proteoglycan (PG) and collagen is critical to evaluate progress of the repair tissue. In the present study Fourier transform infrared imaging spectroscopy (FT-IRIS) was utilized to evaluate molecular changes in normal and degenerated cartilage in a rabbit model of repair. Parameters such as collagen integrity, type II collagen and proteoglycan are important factors in determining the biomechanical properties of articular cartilage, and are likely as important in determining functional competence of repair tissue. Histological evaluations are considered to be one of the most important methods for determining the quality of the repair tissue, but still do not predict clinical outcome. It is possible that a new tissue scoring system that considers molecular parameters in the repair tissue, along with the histological outcomes, will better predict clinical success of repair. The main goal of this study is to assess correlations between histological grading, immunohistochemical assessments of type I and II collagen, and FT-IRIS parameters, in cartilage repair tissue in a rabbit model. These data will provide the basis for a novel tissue scoring system using FT-IRIS parameters alone, or in conjunction with histological and immunohistochemical outcomes. This could yield better correlations with clinical outcomes that may lead to optimization of the cartilage repair process.
Temple University--Theses
Hill, Esme. "Perfusion imaging and tissue biomarkers for colorectal cancer." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:4a309265-6f27-4839-9259-f19cf9648c2d.
Повний текст джерелаWekselblatt, Joseph. "Imaging Neural Circuits Underlying Learning and Behavior." Thesis, University of Oregon, 2018. http://hdl.handle.net/1794/23176.
Повний текст джерела2019-01-09
O'Brien, David Patrick. "Micromachined microelectrode arrays for stimulation of neural tissue." Diss., Georgia Institute of Technology, 2000. http://hdl.handle.net/1853/14993.
Повний текст джерелаSteinmeyer, Joseph D. (Joseph Daly). "Automation of single-cell techniques in neural tissue." Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/90004.
Повний текст джерелаCataloged from PDF version of thesis.
Includes bibliographical references (pages 125-140).
The highly heterogeneous nature of cells in the context of native tissue environments necessitates the development of tools and techniques that can manipulate and analyze samples with single-cell resolution. While the past decades have seen significant progress in analyzing individual cells in tissue, both electrically and morphologically, the ability to genetically manipulate and biochemically analyze such cells in a high-throughput manner has seen only limited advances, and therefore a significant technological gap in accessing cells with single-cell specificity in tissue remains. We present a system design and workflow that fills in this gal) in technology through the implementation of precision automation and redesign of standard biological techniques, resulting in greatly improved throughput while maintaining single-cell accuracy and precision. This thesis comprises three parts: First we discuss the design and implementation of an expandable computer-controlled automation system enabling the rapid maneuvering and targeting of inicropipettes within tissue environments as well as a methodology for cleaning and reuse of these micropipettes to enable significant gains in throughput. Second we apply this automation to transfecting neurons in brain slices with DNA and RNA for subsequent analysis with greater throughput than previous methods. Third, we apply our automation to collecting the contents of single neurons embedded in relevant tissue environments for molecular analysis. The work presented greatly improves the throughput of traditional single-cell methods of transfection and cell-sampling by between one and two orders of magnitude and fills in a gap in the workflow of the rapidly expanding field of single-cell analysis.
by Joseph D. Steinmeyer.
Ph. D.
Stopek, Joshua B. "Bipolymer-microglia cell compositions for neural tissue repair." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0001105.
Повний текст джерелаBarnes, Samesha Rosánne. "Injectable biopolymer gel compositions for neural tissue repair." [Gainesville, Fla.] : University of Florida, 2009. http://purl.fcla.edu/fcla/etd/UFE0024088.
Повний текст джерелаHofstad, Erlend Fagertun. "Ultrasound Contrast Imaging - Improved Tissue Suppression in Amplitude Modulation." Thesis, Norwegian University of Science and Technology, Department of Electronics and Telecommunications, 2006. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-9316.
Повний текст джерелаThe ability to image myocardial perfusion is very important in order to detect coronary diseases. GE Vingmed Ultrasound uses contrast agent in combination with a pulse inversion (PI) technique to do the imaging. But this technique does not function sufficiently for all patients. Therefore have other techniques been tested out, including transmission of pulses with different amplitude (AM), to enhance the nonlinear signal from contrast bubbles. But a problem achieving sufficient cancellation of linear tissue signal is a feebleness of the method. In this diploma work has an effort been put into enhancing the tissue suppression in amplitude modulation. First the source of the lack of suppression was searched for by measuring electrical and acoustical pulses. The further examination revealed a dissymmetry in between pulses of different amplitude. To reduce this error were several attempts to make a compensation filter performed, which finally resulted in a filter created of echo data acquired from a tissue mimicking phantom. The filter was furthermore tested out on a flow phantom to see how it affected the signal from tissue and contrast bubbles, compared to the former use of a constant instead of the filter. The comparison showed 1.5-3.2 dB increase in tissue suppression (TS). But unfortunately did the filtering process slightly reduce the contrast signal as well, which resulted in a smaller increase of Contrast-to-Tissue-Ratio (CTR) than TS; 1.0-2.8 dB. During the work was the source of another problem concerning tissue suppression discovered. In earlier work by the author cite{prosjekt} the experimental results suffered from low TS around the transmitted frequency, which was found inexplicable at that time. This problem was revealed to be caused by reverberations from one pulse, interfering with the echoes from the next pulse. The solution suggested in this thesis is to transmit pulses in such a way that every pulse used to create an image has a relatively equal pulse in front. For instance, if a technique employs two pulses to create an image, and the first has half the amplitude and opposite polarity of the second. Then, to eliminate the reverberations must the first imaging pulse have a pulse in front which has half the amplitude and opposite polarity of the pulse in front of the second imaging pulse.
Ke, Meng-Tsen. "Optical clearing and deep-tissue fluorescence imaging using fructose." 京都大学 (Kyoto University), 2014. http://hdl.handle.net/2433/188839.
Повний текст джерелаPašović, Mirza. "Tissue harmonic reduction : application to ultrasound contrast harmonic imaging." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10060.
Повний текст джерелаUltrasound contrast agents are small micro bubbles that respond nonlinearly when exposed to ultrasound wave. The nonlinear response gives possibility of harmonic ultrasound images which has many advantages over fundamental imaging. However, to increase ultrasound contrast harmonic imaging performance we must first understand nonlinear propagation of ultrasound wave. Nonlinear propagation distorts the propagating wave such that higher harmonics appear as the wave is propagating. The theory that was laid down, was allowed implementing a new method of modelling nonlinear ultrasound propagation. The knowledge obtained during this process was used to construct a multiple component second harmonic reduction signal for reduction of their harmonics generated due to the tissue nonlinearities. As a consequence detection of ultrasound contrast agents at higher harmonics was increased. Further more, a powerful ultrasound imaging technique called Pulse Inversion, was further enhanced with multiple component second harmonic reduction signal. What was learned during investigation of the Pulse Inversion, technique lead to a new phase coded ultrasound contrast harmonic method called second harmonic inversion;. Also it was noted that for different type of media the level of distortion of ultrasound pulse is different. It depends largely on the nonlinear parameter B / A. Although the work on this parameter has not been finished it is very important to continue in this direction since B / A imaging with ultrasound contrast agents has a lot of potential
Walker, Paul Michael. "A test material for tissue characterization in N.M.R. imaging." Thesis, Imperial College London, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338275.
Повний текст джерелаUtting, Jane Francis. "Magnetic resonance imaging of tissue microcirculation in experimental studies." Thesis, University College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272348.
Повний текст джерелаWinder, Robert John. "Medical imaging : tissue volume measurement & medical rapid prototyping." Thesis, University of Ulster, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399689.
Повний текст джерелаLee, Z. S. "Towards real-time imaging of strain in soft tissue." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/20003/.
Повний текст джерелаMeeus, Emma Maria. "Investigation of tissue microenvironments using diffusion magnetic resonance imaging." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8372/.
Повний текст джерелаZhang, Yu. "Hyaluronan Based Biomaterials with Imaging Capacity for Tissue Engineering." Doctoral thesis, Uppsala universitet, Institutionen för kemi - Ångström, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-300799.
Повний текст джерелаShukla, Vipul. "Intravital Imaging of Borrelia burgdorferi in Murine Skin Tissue." University of Toledo Health Science Campus / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=mco1271697663.
Повний текст джерелаZhao, Mingjun. "NONINVASIVE MULTIMODAL DIFFUSE OPTICAL IMAGING OF VULNERABLE TISSUE HEMODYNAMICS." UKnowledge, 2019. https://uknowledge.uky.edu/cbme_etds/58.
Повний текст джерелаZhu, Danyi. "Imaging Fast Neural Activities with Electrical Impedance Tomography." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23477.
Повний текст джерелаRoy, Ranadhir. "Image reconstruction from light measurements on biological tissue." Thesis, University of Hertfordshire, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338567.
Повний текст джерелаSegura, Carlos Alejandro. "Development of an optrode for characterization of tissue optical properties at the neural tissue-electrode interface." Thesis, Boston University, 2014. https://hdl.handle.net/2144/21118.
Повний текст джерелаThe use of implantable neural probes has become common, both for stimulation and recording, and their applications range from chronic pain treatment to implementation of brain machine interfaces (BMI). Studies have shown that signal quality of implanted electrodes decays over time mainly due to the immune response. Characterization of the tissue-electrode interface is critical for better understanding of the physiological dynamics and potential performance improvement of the electrode itself and its task. This work describes the fabrication of an implantable electrode with optical measurement capabilities for providing means to characterize the tissue-electrode interface using optical spectroscopy. The electrode has a set of waveguides embedded in its shanks, which are used to inject white light into tissue and then collect the light reflected from the tissue surrounding the shanks. The collected light was analyzed with a spectrometer and the spectra processed to detect changes in optical properties, information that allows to track physiological changes. It is believed that the immune response can be correlated to changes in scattering as more cells are recruited to the injury site. The increased cell density in local injury/implantation sites increases the amount of scattering due to the increased number of cell nuclei and membranes that light encounters in its path. Investigation of scattering and absorption coefficients in such interface and their change over time can provide useful data for modeling and determining physiological parameters like blood oxygenation while the actual shape of the acquired spectra might highlight particular phenomena that can be indicative of scaring process or hemorrhaging. Validation of this system was done using optical phantoms based on polystyrene spheres and solutions with various concentrations of fat emulsion, which yielded scattering coefficients similar to those of brain tissue. Results suggest that the developed optrodes are able to detect differences between samples with different scattering coefficients. Improvements of fabrication process are discussed based on experimental results and future work includes attempting to perform fluorescence measurements of voltage reporters for optogenetic applications. The ultimate goal of this project was to create a novel device that is capable of satisfying the unmet need of tissue characterization at the implanted electrode interface as well as a tool for the optogenetics field suitable for greater depths than those a microscope can achieve.
Aldoori, Ayat Dhia. "Elucidation of signaling mediators between adipose and neural tissue." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1407845819.
Повний текст джерела