Дисертації з теми "IFM development"
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Ren, Jun P., Lin Wang, Juan Zhao, Ling Wang, Shun B. Ning, Gazzar Mohamed El, Jonathan P. Moorman, and Zhi Q. Yao. "Decline of miR-124 in Myeloid Cells Promotes Regulatory T-cell Development in Hepatitis C Virus Infection." Digital Commons @ East Tennessee State University, 2016. https://doi.org/10.1111/imm.12680.
Повний текст джерелаBach, Dang Phong. "Development of a finite element strategy for the modeling of nano-reinforced materials." Thesis, Compiègne, 2020. http://bibliotheque.utc.fr/EXPLOITATION/doc/IFD/2020COMP2550.
Повний текст джерелаThe modelization of nano-reinforced material requires to take into account the size effect caused by the local phenomena at the interface between the nano-inclusion and the matrix. This size effect is interpreted through an increase in the ratio interface/volume and can be taken into account by introducing a surface elasticity at the interface. Whereas a lot of works have been developed from the analytical point of view, few contributions are related to numerical description and implementation of such surface elasticity in Finite Element Method (FEM). Our studies aim to develop efficient numerical tools based on FEM for the modeling of nanocomposites. Firstly, we evaluate the two existent numerical strategies namely the XFEM approach and the Interface element approach in reproducing the size effect in the homogenization process. Secondly, based on a performance test on the three types of formulations of E-FEM for the case of weak discontinuity, we propose an enhanced SKON formulation allowing to incorporate the effect of a coherent interface. Finally, the numerical modeling on the nonlinear behavior of nanocomposites is investigated. In the first step, a von Mises type elastoplastic law with linear isotropic hardening is considered for the bulk while the interface is considered as linear elastic
Jayaraman, Radhakrishnan. "Development of an interactive programming system for IBM 7545 robot." Thesis, Virginia Polytechnic Institute and State University, 1986. http://hdl.handle.net/10919/90945.
Повний текст джерелаM.S.
Mohandas, Velluva P. "Development of an interactive graphical simulator for the IBM 7545 robot." Thesis, Virginia Tech, 1987. http://hdl.handle.net/10919/41566.
Повний текст джерелаIn this work an enhanced graphical simulator for the IBM 7545 robot running on the AML/E language was developed. The simulator provided two views with the facility to chose either one as the major view, and pan/zoom into that view. It gives the user the facility to define equipment and workcell setups, accepting data in the Intemational Graphics Exchange Specification (IGES) Version 3.0 format. The user can interactively simulate either the complete program, partial program or any subroutine. The system was integrated including the facility to edit, compile, generate cross references, set system configuration, simulate and run the robot either continuously or interactively.
The system was developed on an IBM Personal Computer using two monitors, text and enhanced graphics for maximizing the display surface for the graphics. The programs developed for this work can be broadly classified into the various menu programs, the definition programs to define and display the equipments and workcells, and the graphic programs for driving and displaying the graphics and altering the views.
The limitations and assumptions made in developing this system along with the scope for further work are presented.
Master of Science
Wang, Xisheng. "Mechanisms of IFN-gamma-mediated Resistance against Development of Toxoplasmic Encephalitis." Diss., Virginia Tech, 2006. http://hdl.handle.net/10919/30268.
Повний текст джерелаPh. D.
Stewart, Claire Emma. "Viruses and the interferon (IFN) response : methods to improve production and to rapidly select IFN-sensitive viruses for vaccine development." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/11346.
Повний текст джерелаRajnoch, Adam. "Implementace podpory studia v nástroji IBM Cognos." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-150098.
Повний текст джерелаJunior, Claudionei Nalle. "Indicador de Desenvolvimento Municipal (IDM): uma proposta de caracterização dos municípios brasileiros." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/96/96132/tde-30012015-111453/.
Повний текст джерелаThis thesis arises from the inherent multidisciplinary to development issues and from the perception of the need for new information and management tools to enable public managers when dealing with certain actions and policies. The effort focuses on the understanding of the phenomenon development and discusses the use of indicators in public administration. The problem it proposes refers to a complex context, and its construction emphasizes interdisciplinarity, since it employs concepts and discussions from other disciplines such as Geography, Economics, Sociology, Administration and Political Science. In this sense, there is a clear need for convergence of the various areas of knowledge, once, in the social environment, various concepts coexist. The structure of the paper approaches the understanding of two issues: the development and the territory, and it seeks to understand their relationship with a central debate of great importance, which is the thesis main goal: characterizing Brazilian municipalities as territories from the perspective of development. In order to accomplish it, it was built a nationwide database through the tabulation and consolidation of data provided by IBGE - Brazilian Institute of Geography and Statistics; INEP - National Institute for Educational Studies and Research Anísio Teixeira; and the Ministry of Health. This database allowed contributing to the de discussion of territorial development, its measurement and uses, as well as understanding particular territorial dynamics, which triggers public policies. In addition, among other observations, it was possible to uncover a new view of the rural phenomenon in Brazil and to propose a new classification of Brazilian municipalities either in urban or rural territories.
Pretorius, Leandri. "The economics of animal welfare: an appraisal of welfare issues ifn the South African poultry industry." Master's thesis, University of Cape Town, 2012. http://hdl.handle.net/11427/12191.
Повний текст джерелаIncludes bibliographical references.
Growing consumer awareness of animal welfare has co-evolved with increases in intensive farming, particularly of battery chickens. This rise in consumer awareness recently saw bans on battery farming in parts of Europe. This thesis addresses the difficulties that would follow any similar attempt to curtail battery farming in South Africa. It examines the literature on animal rights and the welfare issues generated by intensive animal farming, particularly of battery chickens. Thereafter it summarises the findings of surveys into local consumer preferences and retail strategies regarding chicken products.
Maity, Chaitali. "Determining the role of a candidate gene in Drososphila muscle development." Oxford, Ohio : Miami University, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=miami1145459719.
Повний текст джерелаWilliams, Kyle C. "Essential functions of IFA-2 domains in Caenorhabditis elegans fibrous organelles." University of Toledo / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1333748571.
Повний текст джерелаFedoročko, Peter. "Current topics in cost allocation and custom API development in IBM Cognos TM1." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-149996.
Повний текст джерелаGomez, Jose A. "Development of Cell Penetrating Bax Inhibiting Peptides (BIP)." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1252025677.
Повний текст джерелаSchuh, Christina. "Development of an IFN-γ-recall assay for porcine reproductive and respiratory syndrome virus". Diss., Ludwig-Maximilians-Universität München, 2014. http://nbn-resolving.de/urn:nbn:de:bvb:19-174194.
Повний текст джерелаMurphy, Jamie Ellen. "Development and evaluation of a sarcocystis neurona-specific IgM capture enzyme linked immunosorbent assay." The Ohio State University, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=osu1399903151.
Повний текст джерелаLindeque, Roelof Cornelius. "Integrated environmental management (IEM) in South Africa : a critical asses[s]ment / Roelof Cornelius Lindeque." Thesis, North-West University, 2003. http://hdl.handle.net/10394/344.
Повний текст джерелаThesis (M. Environmental Science)--North-West University, Potchefstroom Campus, 2004.
Delshad, Payman. "Behavior Driven Development in a Large-Scale Application : Evaluation of Usage for Developing IFS Applications." Thesis, Linköpings universitet, Programvara och system, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-125341.
Повний текст джерелаHajník, Julius. "Řízení požadavků při vývoji softwaru v nástroji IBM Rational Requirements Composer." Master's thesis, Vysoká škola ekonomická v Praze, 2012. http://www.nusl.cz/ntk/nusl-197256.
Повний текст джерелаWatt, James Penn. "A Highly Abstracted Method of FPGA-Based Development for Secondary Surveillance Radar Transpond Detection." DigitalCommons@CalPoly, 2009. https://digitalcommons.calpoly.edu/theses/148.
Повний текст джерелаOlson, J. Jeanene (Joyce Jeanene). "What Do You Say After You've Said "I'm Sorry"? The Development of a Measure of Supportive Communication." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc500404/.
Повний текст джерелаChawla, Lovelesh. "Use of IBM Collaborative Lifecycle Management Solution to Demonstrate Traceability for Small, Real-World Software Development Project." UNF Digital Commons, 2015. http://digitalcommons.unf.edu/etd/606.
Повний текст джерелаBarreto, Maria Simone Prates. "Competências e estratégias para o desenvolvimento de líderes globais: o caso IBM." Pontifícia Universidade Católica de São Paulo, 2016. https://tede2.pucsp.br/handle/handle/18994.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
The main aim of this study was to analyse the competences and development strategies employed by companies, in Brazil, in order to develop global leaders. Qualitative research was carried out to delve into the matter, and the research method was in-depth case study developed at IBM. Data were collected through semi-structured interviews at the reference centre of international recognition, Dom Cabral Foundation, in 2014, by means of several meetings. Secondary data were likewise collected through internet research. The company was chosen owing to its renowned recognition in the global market and great investment in the development of its global leaders. All data collected were analysed through thematic analysis methodology aided by software NVivo, developed by QSR International, and VUE (Visual Understanding Environment), which is open source software. The main competences mentioned by the global leaders at IBM were: easiness in making interpersonal contact; enjoying and valuing people; flexibility and adaptability; being fluent in several languages; being a good communicator; knowing how to deal with cultural diversity; forming and managing remote teams; building networking and partnerships; being good at negotiating; having sense of ethics, discipline and organization; business vision; taking risks; being inspiring and visionary. IBM employs several approaches to develop its global leaders, among which: CSC (Corporate Service Corps), coaching, through which a team of employees from various countries engage in countries under development aiming at assisting NGOs. In addition, there is a strong culture of using feedback, assessment, shadowing model, mentoring, expatriation, licence to work in other countries, programme for exchange of experiences and interaction with people from other countries, and online and face-to-face training. Although the main objective of this study was to analyse the competences and strategies used in development of global leaders at Brazilian companies, it also focused on the profile of the global leaders, the management systems of human resources used at a global company, the challenges the leaders face when developing their work, how they perceive cultural differences, how they see differences between local and global leaders, their career paths and responsibilities
O objetivo central deste trabalho foi o de estudar as competências e as estratégias de desenvolvimento usadas nas empresas, no Brasil, para o desenvolvimento dos líderes globais. Foi realizada pesquisa qualitativa de natureza exploratória, e o método de pesquisa utilizado foi o estudo de caso em profundidade, na empresa IBM. Os dados foram coletados por meio de entrevistas semiestruturadas e no centro de referência de valor internacional, da fundação Dom Cabral, em 2014, através de várias reuniões; os dados secundários foram levantados por meio de pesquisas na internet. A empresa foi selecionada pelo amplo reconhecimento de sua atuação global e pelo grande investimento no desenvolvimento dos seus líderes globais. Os dados foram analisados por metodologia de análise temática e com o auxílio dos softwares: NVivo, desenvolvido pela QSR International, e VUE (Visual Understanding Environment), que é um software livre. As principais competências citadas pelos líderes globais da IBM foram: facilidade em estabelecer contatos interpessoais; gostar e valorizar as pessoas; flexibilidade e adaptabilidade; ter fluência em vários idiomas; boa comunicação; saber lidar com a diversidade cultural; criar e gerir equipes remotas; construir networking e parcerias; negociação; ética; disciplina e organização; visão de negócios; assumir riscos; ser inspirador e visionário. A IBM utiliza várias abordagens para desenvolver seus líderes globais, dentre as quais: CSC (Corporate Service Corps), coaching, na qual uma equipe com funcionários de vários países atua em países em desenvolvimento, com o objetivo de auxiliar ONGs. Também existe forte cultura com intensivo uso de feedback, assessment, modelo de shadow, mentoring, expatriação, licença para se trabalhar em outros países, programa com trocas de experiências e interações com pessoas de vários países, e treinamentos online e presencial. Mesmo sendo o objetivo central deste trabalho estudar as competências e as estratégias de desenvolvimento usadas nas empresas brasileiras para o desenvolvimento dos líderes globais, elucidou-se ainda o seu contexto de trabalho, o perfil dos líderes globais, os sistemas de gestão de recursos humanos de uma empresa global, os desafios que eles encontram no seu trabalho, como eles percebem as diferenças culturais, como veem as diferenças de atuações de líderes locais e globais, suas trajetórias de carreiras e suas responsabilidades
Schmid, Manuela. "Eimeria falciformis infection of mouse cells identifies host determinants of parasite development." Doctoral thesis, Humboldt-Universität zu Berlin, Mathematisch-Naturwissenschaftliche Fakultät I, 2014. http://dx.doi.org/10.18452/17001.
Повний текст джерелаEimeria falciformis is a highly host- and tissue-specific parasite of murine caecum epithelium. Its monoxenous life cycle in a well-investigated host makes it an excellent model to examine parasite-host interactions. To identify the host determinants of the parasite infection, this work involved the comparative in vitro and in vivo analyses of mouse gene modulation by E. falciformis. The in vitro microarray analyses identified the transcription factor FBJ osteosarcoma oncogene (c-FOS) as highly induced during E. falciformis infection. C-FOS is part of the activator protein 1 (AP-1) complex, which controls the transcription of genes involved in various biological processes. We show that infection of c-FOS-deficient mouse cells results in an impaired development of E. falciformis, highlighting an exploitation of the host transcription factor by an apicomplexan parasite. Our ex vivo gene expression analyses using mouse caecum cells revealed a substantial modulation of the host transcriptome. The indoleamine 2,3-dioxygenase 1 (IDO1), the first and rate-limiting enzyme of tryptophan catabolism in the kynurenine pathway, was one of the most up-regulated epithelial transcripts. Induction of IDO1 supposedly depletes tryptophan in host cells, which is proposed to inhibit the in vitro growth of pathogens auxotrophic for this essential amino acid. We show that E. falciformis induces IDO1 in the epithelial cells in an IFN-gamma-dependent manner. The absence or inhibition of IDO1 and two downstream enzymes of the pathway in the mouse impairs parasite growth. Noticeably, the parasite development was entirely rescued by xanthurenic acid, a by-product of tryptophan catabolism. These data demonstrate contrasting roles of IFN-gamma signaling and a conceptual subversion of the host defense (IFN-gamma, IDO1) by an intracellular pathogen for progression of its natural life cycle.
CANNAS, VALERIA. "Exploitation of Ebola Virus VP35 Protein to identify new drugs counteracting its type I IFN antagonism." Doctoral thesis, Università degli Studi di Cagliari, 2015. http://hdl.handle.net/11584/266615.
Повний текст джерелаWilliams, Patrick. "The development and characterization of fusion cytokines of GMCSF with IL-21 and IFN-y for cancer immunotherapy." Thesis, McGill University, 2011. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=96679.
Повний текст джерелаDifférentes stratégies immunothérapeutiques ont été considérées contre le cancer, allant de l'utilisation de cytokines comme l'IL-2, aux cellules dendritiques, tel que Provenge, ou à la combinaison de cellules modifiées génétiquement pour exprimer des cytokines produisant des vaccins cellulaires, tel que GVAX. Ces méthodes immunothérapeutiques ont progressé lentement puisque d'une part, la réponse immunitaire n'était pas efficace, et d'une autre part, l'hétérogénéité du cancer peut limiter l'efficacité à produire une réponse immunitaire contre un antigène particulier. Des recherches antérieures au sein de notre laboratoire ont révélé que la fusion de GMCSF avec la famille des cytokines de la chaîne gamma du récepteur de l'IL-2 ont produit des effets immunomodulateurs sans précédent. De plus, les cellules traitées avec ces cytokines fusionnées pourraient être efficaces dans le traitement de maladies chez les souris.Nous avons généré la fusion de GMCSF et IL-21 (GIFT-21) dans le but de stimuler des éléments distincts, mais complémentaires, du système immunitaire inné et adaptif. Les interactions aberrantes de GIFT-21 avec ses récepteurs des macrophages ont produit une réponse pro-inflammatoire inattendue, résultant en un rejet de la lignée cellulaire B16 des souris C57B1/6 et une survie significative des souris NOD SCID. Nous avons exploré davantage ce phénomène en injectant des souris avec des cellules dendritiques (DC) dérivées en traitant des monocytes avec GIFT-21. La croissance des cancers B16 et D2F2/neu a seulement été inhibée dans les souris injectées avec des cellules dendritiques traitées avec GIFT-21 sans pré-incubation avec un antigène. Par contre, cet effet n'a pas été observé dans les souris CD8-/- et CCR2-/-, ni lorsque nous avons injecté des souris avec des cellules dendritiques GIFT-21 déficientes en microglobuline β2. Nous avons confirmé que les cellules dendritiques GIFT-21 ont migré vers les tumeurs et les ont échantillonées afin de présenter des antigènes à travers MHCI à des cellules T CD8+ recrutées par CCL2. Nous avons également généré une fusion de GMCSF et IFN-γ (GIFY) dans le but d'induire une réponse pro-inflammatoire chez les cellules dendritiques et d'ainsi améliorer leur habileté a présenter des antigènes. Nous avons confirmé que GIFY possède des propriétés cytostatiques supérieures à IFN-γ et qu'il pourrait induire les cellules dendritiques à présenter des antigènes à travers des cellules T CD8+ similaires à la combinaison de GMCSF et IFN-γ. Par contre, GIFY s'est montré inefficace à prévenir la croissance des tumeurs lorsqu'injecté en tant que recombinante purifiée dans des souris avec des tumeurs B16 et lorsqu'utilisé en tant qu'adjuvant sous forme de vaccin pour des cellules dendritiques contre un lymphome EG-7. Nous pouvons conclure que GIFT-21 et ses produits cellulaires pourront servir de plate-forme thérapeutique sans précédent pour le traitement du cancer et que GIFY pourrait être approprié dans d'autres contextes.
Ding, Cheng. "Siglec-G Is A Negative Regulator Of Nf-Kb Activation And Has Pivotal Roles In B-1 Cell Development And Resistance To Sepsis." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1226876722.
Повний текст джерелаBouis, Delphine. "Etude des conséquences d’un gain de fonction de Sting chez la souris : modèle STING V154M/WT." Thesis, Strasbourg, 2018. http://www.theses.fr/2018STRAJ063.
Повний текст джерелаIn humans, point mutations in STING gene, such as V155M, lead to a severe autoinflammatory disease called SAVI (Sting associated vasculopathy with onset in infancy), classified as interferonopathy and characterized by vasculopathy, pulmonary fibrosis and a lupus-like pathology. In order to better understand the pathophysiology of SAVI, we generated a mouse model with the corresponding mutation, using CRISPR/Cas9 technology. These STING V154M/WT mice develop a SCID (severe combined immunodeficiency disease) with decrease of peripheral T, B and NK cells, and expansion of myeloid compartment. This defect seems to be present since the early stages, i.e. pre-proB cells stage in bone marrow and DN2 stage in thymus, and seems intrinsic to hematopoiectic cells. In addition, these mice present a strong hypogammaglobulinemia. Mature T and B cells also present intrinsic defaults. Finally, these mice present an IFN signature but their phenotype is independent of the IFN pathway. These results highlight an important role of STING in lymphoid development
Santos, Fladson Ricardo Mendes dos. "A percepção dos gestores do Instituto Federal de Sergipe – IFs campus lagarto acerca das licitações sustentáveis." Universidade Federal da Paraíba, 2017. http://tede.biblioteca.ufpb.br:8080/handle/tede/9042.
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The need for nations to promote the growth of their economies without destroying the environment or sacrificing the well-being of future generations, transforming especially the business world, has become a challenge today. In view of it is fundamental relevance, sustainability has become more and more space in the various discussions, and in recent times the focus has been on the Public Administration, most probably for its state power, with a constitutional duty to implement public policies that collaborate with the economy. In the use of natural resources, ensuring their preservation and contributing effectively to the possibility of providing these resources for the future generations. The present study aims to diagnose the perception of the managers of the Instituto Federal de Sergipe (IFS) – Campus Lagarto, about the Sustainable Biddings. Methodologically, the study is classified as a field research, as the qualitative-descriptive approach, using a structured questionnaire for data collection, for treatment of clusters technique, allied to an index called Degree of Vision About Sustainable Biddings (GVLS). The results point to the fact that managers are sensitized about the possibility of behavioral changes, be they of a functional or institutional nature, for the adoption of Sustainable Biddings. Thus IFS – Campus Lagarto is suggested to implement Sustainable Biddings, using the Regulation and Standardization of Tender Procedures, Formatting a Sustainable Biddings Plan, Creating Environmental Education Programs for Managers and Periodic Surveys of Environmental Perception, Covering the Internal and External Community and Strengthening Internal Communication about Current Procedures and Standards.
A necessidade das nações de promover o crescimento de suas economias sem destruir o meio ambiente ou sacrificar o bem-estar das futuras gerações, transformando sobretudo, o mundo dos negócios, tornou-se um desafio na atualidade. Diante da sua primordial relevância, a sustentabilidade passou a ocupar cada vez mais espaço nas diversas discussões e nos últimos tempos os olhares estão voltados para a Administração Pública, muito provavelmente pelo seu poder estatal, com dever constitucional de implementar políticas públicas que colaborem com a economia na utilização dos recursos naturais, garantindo sua preservação e contribuindo efetivamente com a possibilidade do provimento desses recursos para as gerações futuras. O presente estudo tem como objetivo diagnosticar a percepção dos gestores do Instituto Federal de Sergipe (IFS) – Campus Lagarto, acerca das licitações sustentáveis. Metodologicamente, o estudo classifica-se quanto aos procedimentos como pesquisa de campo, quanto a abordagem como qualitativa-descritiva, utilizando-se de um questionário estruturado para coleta dados, para tratamento a técnica de clusters, aliada a um índice denominado Grau de Visão Sobre Licitações Sustentáveis (GVLS). Os resultados apontam para o fato de que os gestores se sensibilizam sobre a possibilidade de mudanças de comportamento, seja de ordem funcional ou institucional, para a adoção das licitações sustentáveis. Assim, sugere-se ao IFS – Campus Lagarto, a implementação das licitações sustentáveis, utilizando-se da regulamentação e padronização dos procedimentos licitatórios, formatação de um plano de contratações sustentáveis, criação de programas de educação ambiental extensiva a gestores e servidores, aplicação de pesquisas periódicas de percepção ambiental, abrangendo a comunidade interna e externa e fortalecendo a comunicação interna acerca de procedimentos e normas vigentes.
MAFRA, Wankmar Carvalho. "O papel do Instituto Federal do Amazonas no processo socioeducacional na Regi?o do Alto Solim?es." Universidade Federal Rural do Rio de Janeiro, 2016. https://tede.ufrrj.br/jspui/handle/jspui/2170.
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This research was conducted in the Federal Amazon Institute (IFAM Campus Tabatinga-AM), and to investigate, on the prospects of its graduates students, its contribution to the local and regional social and educational development, and investigate what the real contributions were in life of its graduates. This research was a universe of 179 (one hundred and seventy nine) students graduating from technical courses integrated and concomitant average level, which responded to the survey instrument comprised of closed and semi-open questions, subdivided and three groups of question: i) graduate student profile. ii) level of satisfaction according to the perception of graduate student and iii) perception of graduate student about the IFAM's contribution in their training. The methodological framework included empirical research conducted among students graduating from Federal Institutes (as shown in PPGEA) as well as the literature research with students graduating from educational institutions. As a result of the survey showed that the IFAM Tabatinga Campus has offered a differentiated training in the municipality, which is deployed as a result of the sum of several factors: a good infrastructure; a staff of well qualified professionals; diversity in educational environments and above all a special attention to your audience. In this sense the research concluded that the IFAM Campus Tabatinga has initially attended the high school education expectations and local technical, with a little emphasis on the mesorregional development of Alto Solim?es contributing effectively in the process of educational development, human and social location.
Esta pesquisa foi realizada no Instituto Federal do Amazonas (IFAM Campus Tabatinga-AM), tendo como objetivo investigar, sob as perspectivas de seus estudantes egressos, a contribui??o do mesmo para o desenvolvimento socioeducacional local e regional, e investigar quais foram as reais contribui??es na vida de seus egressos. Tal pesquisa contou com um universo de 179 (cento e setenta e nove) estudantes egressos dos cursos t?cnicos de n?vel m?dio integrado e concomitante, os quais responderam ao instrumento de pesquisa formado por perguntas fechadas e semiabertas, subdivididas e tr?s grupos distintos de quest?o: i) perfil do estudante egresso. ii) n?vel de satisfa??o de acordo com a percep??o do estudante egresso e iii) percep??o do estudante egresso acerca da contribui??o do IFAM na sua forma??o. O arcabou?o metodol?gico incluiu pesquisas emp?ricas realizadas entre estudantes egressos de Institutos Federais (como os apresentados no PPGEA), bem como a literatura a respeito de pesquisas com estudantes egressos de institui??es educacionais. Como resultado a pesquisa mostrou que o IFAM Campus Tabatinga tem ofertado uma forma??o diferenciada no Munic?pio, no qual est? implantado, em decorr?ncia da soma de diversos fatores como: uma boa infraestrutura; um quadro de profissionais muito bem qualificados; diversidade em ambientes educacionais e acima de tudo uma aten??o diferenciada com o seu p?blico. Nesse sentido a pesquisa concluiu que o IFAM Campus Tabatinga tem atendido inicialmente ?s expectativas de educa??o de ensino m?dio e t?cnico local, com uma pequena ?nfase para o desenvolvimento mesorregional do Alto Solim?es contribuindo de maneira efetiva no processo de desenvolvimento educacional, humano e social local.
Löfstedt, Truls, and Daniel Jonsson. "Att koordinera distribuerade IT-projekt med stöd av informations- och kommunikationsteknik : En fallstudie på IFS World Operations AB." Thesis, Linköpings universitet, Institutionen för ekonomisk och industriell utveckling, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-79014.
Повний текст джерелаInformation systems are often developed in globally distributed organizations. Many times the reason for being distributed is to meet requirements and demands from the organizations surrounding and to acquire a specialized set of skills. Global organizations may choose to work distributed, which means that development teams are spread out over multiple locations. This can create problems; how do you make all parts of the organization work together towards a common goal? Thus, coordination – The management of interdependent elements in a complex organization so as to enable them to work together effectively toward a specific goal – becomes important. Long distance communication using information and communication technology (ICT) – digital tools with the purpose of endorsing communication and knowledge – is required to coordinate between locations. In this thesis we examine how coordination is performed in distributed IT-projects. We will also address the role that information and communications technology plays in coordination of these projects. The purpose of the study is to contribute with knowledge in the area of using ICT tools for coordinating distributed IT-projects. This qualitative case study was conducted in cooperation with IFS World Operations AB – a global provider of an Enterprise Resource Planning system. Our empirical data has been collected using five interviews, all with different types of roles from within IT-projects. The data has then been put in relation to theories concerning coordination, IT-projects and ICT. Our findings show coordination in distributed, agile software development projects is working on two levels; strategic and operational coordination. The difference lies with the motivation to complete goals on different levels of the organization. We can also conclude that there are three different kinds of means to carry out coordination; Mutual Adjustment, Emerging standardization and organizational management. Concerning the role of ICT in the coordination of distributed IT-projects we have found it to be threefold; enabling, mediating and limiting. Based on these findings we conclude this study by presenting five factors that influence the ability to coordinate distributed IT-projects. These are: group dynamics, level of distribution, fixed development teams, parallel development of technology and organization and standardized communication channels.
McNutt, Stephen Bishop. ""If I'm so smart...": memories of assessment and the role of standardized testing in forming an intellectual identity." Diss., University of Iowa, 2014. https://ir.uiowa.edu/etd/2244.
Повний текст джерелаSchuh, Christina [Verfasser], та Mathias [Akademischer Betreuer] Ritzmann. "Development of an IFN-γ-recall assay for porcine reproductive and respiratory syndrome virus / Christina Schuh. Betreuer: Mathias Ritzmann". München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2014. http://d-nb.info/1059069741/34.
Повний текст джерелаAlazmi, Huda Salem. "The Development of GIS Instructional Model to Facilitate Authentic Intellectual Work in Secondary Social Studies Classrooms in Kuwait." Diss., Virginia Tech, 2020. http://hdl.handle.net/10919/97906.
Повний текст джерелаDoctor of Philosophy
Geographical Information Systems (GIS) are software-based technologies which simplify the gathering, storing and manipulation of spatially-related data in ways which allow users to visually represent complex geographic phenomena more easily, bringing greater understanding for the world around us. As a result, the integration of GIS technology into social studies classroom practices has assisted student learning and achievement. However, despite the value which GIS possesses, few schools have integrated this technology so far. A significant reason for this limitation is the lack of clear guidelines or models which demonstrate how to employ this technology in the classroom. To help address the problem, this study developed a GIS Instructional Model for Kuwaiti social studies teachers to facilitate student authentic intellectual work, i.e. the student's demonstration of their deeper understanding for the knowledge and skills they are learning. The study employed a design and developmental research methodology, comprised of five major phases, (i) selection of model components and theoretical foundation, (ii) analysis and development, (iii) formative feedback, (iv) revision, and (v) usability evaluation. Phase one involved the selection of the study's theoretical foundation. In phase two, following a comprehensive review of relevant academic literature and, in combination with personal experience, the researcher developed a preliminary GIS Instructional Model. Two expert reviewers evaluated the model in phase three, delivering their opinions by completing an online survey and taking part in follow-up interviews. This feedback was analyzed in phase four, leading to revisions in the GIS Instructional Model to improve its quality for supporting student learning. In the final phase, six Kuwaiti expert reviewers assessed the newly-updated model to determine what barriers it might face regarding its implementation in the Kuwaiti educational system. They completed an online survey as part of this process and provided possible solutions to address these perceived obstacles. This step-by-step procedure helped to validate the model. The overall result was the development of a ready-to-implement teaching model, with all necessary educational materials and instructions, for employing GIS technology in Kuwaiti social studies classrooms to support student authentic intellectual work. In addition, recommendations were provided for Kuwaiti educational policymakers and stakeholders to help overcome perceived obstacles that may hinder model implementation; suggestions for future research are also included.
Vasou, Andri. "Development of a novel cell-based screening platform to identify inhibitors of viral interferon antagonists from clinically important viruses." Thesis, University of St Andrews, 2016. http://hdl.handle.net/10023/8266.
Повний текст джерелаMcLean, Rebecca Kathryn. "Development of a novel lentiviral vaccine vector and characterisation of in vitro immune responses." Thesis, University of Edinburgh, 2018. http://hdl.handle.net/1842/31135.
Повний текст джерелаFrançois-Newton, Véronique. "Etude de la réponse cellulaire aux interférons de type I : rôle de la cystéine protéase USP18." Phd thesis, Université Pierre et Marie Curie - Paris VI, 2012. http://tel.archives-ouvertes.fr/tel-00829540.
Повний текст джерелаLindell, Frans. "BIM I TOTALENTREPRENAD: PROJEKTERINGENS INFORMATIONSLEVERANSER FÖR PRODUKTIONENS GRUNDLÄGGNING." Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH, Byggnadsteknik och belysningsvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-35189.
Повний текст джерелаPurpose: The building industry is characterised by mainly consisting of temporary project organizations with much interdisciplinary cooperation but with little continuity of process between the unique projects. There is a big focus on time and immediate action as part of the actors’ frame of reference, and every activity and new work method should give immediate advantages in time savings and more efficient work to be readily accepted. The need for standardised work methods is very visible when BIM is introduced in the projects. To actively use the BIM-model on site creates demands on the content and that a design schedule is followed. BuildingSMART International (2010) writes: ”If the information required is available when it is needed and the quality of information is satisfactory, the construction process will itself be significantly improved”. The aim of this work is to produce a suggestion of how the sequence of information deliveries should be in the starting production of the loadbearing system in a design build project. Method: To reach the aim a literature study has been conducted to create the theoretical framework for the study. A case study has been conducted on a design build project with a deep foundation. Empirical data has been collected by means of interviewing some of the project actors and conducting a document analysis of project documents such as drawings and protocols. Findings: The report has mapped the sequence of information deliveries (including what information content and what level of development they need to have) for the initial production of the loadbearing system in a design build project. This contribution of knowledge with the process map and information demands can be built upon, to allow for implementation in the BIM tools and thus make the work easier and push the use of BIM forward. Implications: With the above results the report has contributed with a few started puzzle pieces in a big puzzle of information and deliveries in the correct sequence and level of development. To complete the puzzle the information deliveries from the specifications also needs to work correctly. The report has shown advantages by working with BIM in this part of the building process. The report suggests clarification of meaning by using both names, level of detail and level of development, in Sweden. Limitations: The report is limited to describe what information deliveries the contractor needs from the structural designer when it comes to piling and foundations. It also describes the information deliveries needed by the structural designer to be able to meet the information need of the contractor.
Andersson, Simon, and Olof Sundén. "Användandet av Level of Development vid projektering : En kvalitativ studie avseende effektivisering av projekteringsprocessen för konstruktörer." Thesis, Tekniska Högskolan, Högskolan i Jönköping, JTH, Byggnadsteknik och belysningsvetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-45593.
Повний текст джерелаIncháustegui, Pérez Carlos Miguel. "Conections between Foreign Direct Investment, access to natural resources and local development in a mining area: The case of Antamina, Ancash." Pontificia Universidad Católica del Perú. Centro de Investigación en Geografía Aplicada, 2013. http://repositorio.pucp.edu.pe/index/handle/123456789/119427.
Повний текст джерелаDurante los años noventa el Estado peruano adoptó una tendencia neoliberal con el objetivo de reactivar la economía con la atracción de Inversiones Foráneas Directas (IFD). El rubro minero fue uno de los sectores más beneficiados por estas nuevas reformas políticas que habilitaron a una serie de compañías multinacionales explorar y explotar los recursos minerales en los parajes más recónditos del país. La llegada de estas grandes empresas no solo significó un enorme crecimiento macroeconómico sino también una cuantiosa inyección de capital y un cambio en el acceso de los recursos naturales. Estos cambios causaron diferentes protestas en las comunidades campesinas ubicadas en las áreas de influencia minera que dan pie a la creación de nuevas perspectivas de cómo lograr un desarrollo local. Una de las maneras de estudiar las interacciones entre estos dos actores —la mina y las comunidades— es mediante el uso del análisis de discurso y narrativas.De este modo, este artículo tiene como objetivo hallar las conexiones entre IFD, acceso a los recursos y desarrollo local en nueve comunidades en la cuenca del río Ayash y la multinacional Compañía Minera Antamina (CMA). En este sentido, se utilizaron métodos cualitativos para describir y analizar los efectos directos e indirectos en la población y en su acceso a los recursos. También se analizará cómo la ausencia del Estado puede dar cabida a un uso inadecuado de la Responsabilidad Social Corporativa (RSC) y, en consecuencia, motivar a las comunidades a reclamar compensaciones por los daños ambientales. Siguiendo esta línea, se utilizará el Análisis de Discurso para esquematizar estas protestas en forma de narrativas de desarrollo y establecer nuevas consideraciones para futuros y actuales proyectos de IFD en minería.
SANTOS, Breno Bittencourt. "Índice de Felicidade Local (IFL): Uma Proposta Teórico-Metodológica de Construção de Uma Medida de Desenvolvimento Social." Universidade Federal de Pernambuco, 2015. https://repositorio.ufpe.br/handle/123456789/16183.
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CAPEs
A presente pesquisa alinha-se à perspectiva de Desenvolvimento Social, na qual se propõe que, para além de critérios econômicos, o desenvolvimento deve ser mensurado também a partir das dimensões sociais, políticas, culturais e emocionais relativas aos indivíduos, grupos e territórios. Nesta perspectiva, os estudos da felicidade buscam determinar o nível de satisfação dos indivíduos com suas próprias vidas, sendo levada em consideração a análise de fatores socioeconômicos, demográficos, ambientais, culturais e emocionais que podem apresentar relação com a felicidade do indivíduo. A questão que norteou este estudo foi: quais são os fatores e em que medida eles podem servir de parâmetros para a construção de uma medida de desenvolvimento social baseada na mensuração da felicidade? O objetivo geral da pesquisa foi construir uma proposta teórico-metodológica de medida de desenvolvimento social baseada na felicidade, intitulada de Índice de Felicidade Local (IFL) e aplicar o IFL a uma amostra populacional composta por habitantes dos municípios de Cabo de Santo Agostinho e Ipojuca. Para isso, foram utilizados procedimentos estatísticos variados, especialmente a técnica de análise de regressão multivariada, testes de correlação e testes de diferenças de médias. Como resultados verifica-se que a população apresenta altos índices de desigualdade socioeconômica e vulnerabilidade social, especialmente no que tange à escolaridade, aos rendimentos dos trabalhadores e às posições no mercado de trabalho. Neste estudo, observou-se que os indicadores de bem-estar subjetivo apresentam maiores inter-relações com os níveis de felicidade dos indivíduos do que os indicadores objetivos de bem-estar social. Dentre os indicadores de bem-estar subjetivos analisados, constata-se que os indicadores relativos à satisfação com o poder de compra/ capacidade de consumo e à satisfação com as relações familiares e de amizade são os que apresentam maior influência na felicidade dos indivíduos. Estes resultados demonstram que, no contexto analisado, a felicidade tende a ser influenciada por aspectos materiais e não materiais de condições de vida. Por fim, verifica-se que, dentre os grupos populacionais investigados, os imigrantes tendem a apresentar piores condições de bemestar subjetivo e de felicidade que os não migrantes.
This research is aligned with the Social Development perspective, which proposes that, in addition to economic criteria, the development must be measured also from social, political, cultural and emotional concerning to individuals, groups and territories. On this perspective, the happiness studies seek to determine the level of satisfaction of individuals with their own lives, being taken into consideration the analysis of socioeconomic, demographic, environmental, cultural and emotional factors that can present connections with the happiness of the individuals. The question that guided this study was: what are the factors and how they can serve as parameters for the construction of a social development measure based on measuring happiness? The overall objective was to build a theoretical and methodological proposal for social development measure based on happiness, titled Local Happiness Index (LHI) and apply the LHI to a population sample of inhabitants of the municipalities of Cabo de Santo Agostinho and Ipojuca. For this, various statistical procedures were used, especially the multivariate regression analysis technique, correlation tests and tests of mean differences. As a result it turns out that the population has high rates of socioeconomic inequality and social vulnerability, especially with regard to education, the income of workers and positions in the labor market. On this study, the subjective well-being indicators have greater inter-relations with the happiness levels of individuals than objective indicators of social well-being. Among the subjective well-being indicators analyzed, it appears that the indicators regarding satisfaction with the purchasing power/consumption capacity and to meet with the family and friendship relationships are those with greater influence in the happiness of individuals. These results demonstrate that in the context analyzed, happiness tends to be influenced by material aspects and not material living conditions. Finally, it turns out that among the populations investigated, recent immigrants tend to have less level of subjective well-being and happiness in comparison with non-migrants.
Shatnawi, Ehab Salem. "Development of P-Y Criterion for Anisotropic Rock and Cohesive Intermediate Geomaterials." University of Akron / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=akron1216311932.
Повний текст джерелаElfaitouri, Amal. "Development of Real-Time PCR Based Methods for Detection of Viruses and Virus Antibodies." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-7320.
Повний текст джерелаMitagami, Yu. "Interferon-γ promotes inflammation and development of T-cell lymphoma in HTLV-1 bZIP factor transgenic mice". Kyoto University, 2016. http://hdl.handle.net/2433/215454.
Повний текст джерелаDalchiavon, Eloisa Carla. "Desenvolvimento econômico dos municípios paranaenses: análise a partir do índice FIRJAN de Desenvolvimento Municipal (IFDM) para o período de 2005 a 2013." Universidade Estadual do Oeste do Paraná, 2017. http://tede.unioeste.br/handle/tede/3039.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
This study has for general objective to analyze the economic development, measured to IFDM, of the municipality of the state of Parana in the period from 2005 to 2013.The specific objectives are: present the evolution of the IFDM of the municipality of the state of Parana, for the state and geographic mesoregions; analyze the spatial distribution of the developed of the state of Parana in the period from 2005 to 2013 and check the composition of the job in the period, of the mesoregions. For the objectives proposed draw on the descriptive analysis of the data in relation the IFDM, the Exploratory Spatial Data Analysis (ESDA), seeking to view how is spatially distributed the development of Parana, and the method of analyze shiftshare to study the employment performance in the regions and sectors of economic activities. The results found for the descriptive analysis show that the economic development of the states of Parana occur different way between regions, stand out the mesoregions North Central and West, that had greater number of municipalities classified with high development (IFDM general) in 2013. In contrast, the mesoregion Central South didn't present municipalities with high IFDM general, in both the years. The results of the ESDA indicate the existence of the autocorrelation spatial positive in the data, in other words, there is similarity between the values of the IFDM general of the municipalities and their spatial localization. The maps of cluster LISA indicated the existence, in 2005, of the three clusters high-high located in the regions: North Central, Northwest and west of the state, and two clusters low-low located in the regions: Middle Western ,North Central, Middle Oriental and Middle South. In 2013, there was a increase in the number of the significant clusters, and theses lie longer distributed than in 2005. Were indentified four clusters high-high, that belong the regions North Central, Northwest, West and Southwest, and three clusters low-low belong the regions: Middle South, Middle Western, Middle Oriental, North Central, North Pioneer and Southeast. In relation the analyze shift-share of employment of the state, the number of jobs of Parana, from 2005 to 2013, increased 47,98%. It was verified that the three sectors that presented the highest employment growth in the state were: Construction industry; Footwear Industry and Mechanical Industry. In regional terms, the regions Southwest, West, Northwest and North Central stand out with the percentage change of increase of employment greater than state. The group of analysis realized allow to infer the regions that in relation of IFDM general of municipalities are that present clusters of development significant high-high, in other words, the municipalities these regions present high value of IFDM general and they are surrounded by municipalities with high value too. Similarly, the regions with the highest employment growth, according to shift-share analysis, they are that didn't have improve IFDM general and identification of clusters of development high-high.
Este estudo tem por objetivo geral analisar o desenvolvimento econômico, medido por meio do IFDM, dos municípios paranaenses no período de 2005 a 2013. Tem-se como objetivos específicos: apresentar a evolução do IFDM dos municípios paranaenses, para o estado e para as mesorregiões geográficas que o compõem; analisar a distribuição espacial do desenvolvimento dos municípios do Paraná nos anos 2005 e 2013, e verificar a composição do emprego no período, das mesorregiões. Para atender aos objetivos propostos utiliza-se a análise descritiva dos dados em relação ao IFDM, a Análise Exploratória de Dados Espaciais (AEDE), buscando visualizar como está distribuído espacialmente o desenvolvimento do Paraná, e o método de análise estrutural-diferencial para verificar o comportamento do emprego nas regiões e setores de atividades econômicas. Os resultados encontrados pela análise descritiva mostram que o desenvolvimento econômico dos municípios paranaenses ocorreu de forma diversa entre as regiões, destacando-se as mesorregiões Norte Central e Oeste, as quais tiveram o maior número de municípios classificados com alto desenvolvimento (IFDM geral) em 2013. Por outro lado, a mesorregião Centro-Sul não apresentou municípios com IFDM geral alto, em ambos os anos. Os resultados da AEDE indicam a existência de autocorrelação espacial positiva nos dados, ou seja, existe similaridade entre os valores do IFDM geral dos municípios e a sua localização espacial. Os mapas de cluster LISA indicaram a existência, em 2005, de três clusters significativos AltoAlto localizados nas regiões Norte Central, Noroeste e Oeste do estado, e dois clusters significativos Baixo-Baixo localizados nas regiões, Centro-Ocidental, Norte Central, CentroOriental e Centro-Sul. Em 2013, houve um aumento no número de clusters significativos, e estes encontraram-se mais distribuídos do que em 2005. Foram identificados quatro clusters Alto-Alto, que pertencem às regiões Norte Central, Noroeste, Oeste e Sudoeste, e três clusters Baixo-Baixo pertencentes às regiões Centro-Sul, Centro-Ocidental, Centro-Oriental, Norte Central, Norte Pioneiro e Sudeste. Em relação à análise estrutural-diferencial do emprego do estado, tem-se que, o número de empregos do Paraná, de 2005 a 2013, aumentou 47,98%. Verificou-se que os três setores que apresentaram maior crescimento do emprego no estado foram: Construção Civil; Indústria de Calçados e Indústria Mecânica. Em termos regionais, as regiões Sudoeste, Oeste, Noroeste e Norte Central se destacaram com variação percentual de crescimento do emprego maior que a do estado. O conjunto das análises realizadas permite inferir que as regiões que se destacaram em relação ao IFDM geral dos seus municípios foram as que apresentaram clusters de desenvolvimento significativos Alto-Alto, ou seja, os municípios dessas regiões apresentaram alto valor de IFDM geral e estão rodeados por municípios com alto valor também. Do mesmo modo, as regiões que apresentaram maior crescimento do emprego, de acordo com a análise estrutural-diferencial, foram as que tiveram melhores IFDM geral e identificação de clusters de desenvolvimento Alto-Alto.
Foxwell-Norton, Kerrie-Ann, and na. "Communicating the Australian Coast: Communities, Cultures and Coastcare." Griffith University. School of Arts, 2007. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20070814.094758.
Повний текст джерелаSaiz, Nestor. "Regulation of cell fate and cell behaviour during primitive endoderm formation in the early mouse embryo." Thesis, University of Manchester, 2012. https://www.research.manchester.ac.uk/portal/en/theses/regulation-of-cell-fate-and-cell-behaviour-during-primitive-endoderm-formation-in-the-early-mouse-embryo(d40bb786-85ed-4efd-af64-aab331df98e8).html.
Повний текст джерелаFoxwell-Norton, Kerrie-Ann. "Communicating the Australian Coast: Communities, Cultures and Coastcare." Thesis, Griffith University, 2007. http://hdl.handle.net/10072/367816.
Повний текст джерелаThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Arts
Full Text
Guo, Jihao, and Ludger Frerichs. "Development of a hydrostatic transmission with integrated supply for working hydraulics." Technische Universität Dresden, 2020. https://tud.qucosa.de/id/qucosa%3A71237.
Повний текст джерелаParker, Ceth Woodward. "Microbial Iron Reduction In The Development of Iron Formation Caves." University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1542892784053378.
Повний текст джерелаGage, Zoe O. "Interferon, viruses and drug discovery." Thesis, University of St Andrews, 2017. http://hdl.handle.net/10023/10127.
Повний текст джерела