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Статті в журналах з теми "HYPHAL MORPHOGENESIS"
Hazan, Idit, Marisa Sepulveda-Becerra, and Haoping Liu. "Hyphal Elongation Is Regulated Independently of Cell Cycle inCandida albicans." Molecular Biology of the Cell 13, no. 1 (January 2002): 134–45. http://dx.doi.org/10.1091/mbc.01-03-0116.
Повний текст джерелаKornitzer, Daniel. "Regulation of Candida albicans Hyphal Morphogenesis by Endogenous Signals." Journal of Fungi 5, no. 1 (February 28, 2019): 21. http://dx.doi.org/10.3390/jof5010021.
Повний текст джерелаLee, Hye-Jeong, Jong-Myeong Kim, Woo Kyu Kang, Heebum Yang, and Jeong-Yoon Kim. "The NDR Kinase Cbk1 Downregulates the Transcriptional Repressor Nrg1 through the mRNA-Binding Protein Ssd1 in Candida albicans." Eukaryotic Cell 14, no. 7 (May 22, 2015): 671–83. http://dx.doi.org/10.1128/ec.00016-15.
Повний текст джерелаBartnicki-Garcia, S., D. D. Bartnicki, and G. Gierz. "Determinants of fungal cell wall morphology: the vesicle supply center." Canadian Journal of Botany 73, S1 (December 31, 1995): 372–78. http://dx.doi.org/10.1139/b95-271.
Повний текст джерелаNaseem, Shamoon, Esteban Araya, and James B. Konopka. "Hyphal growth inCandida albicansdoes not require induction of hyphal-specific gene expression." Molecular Biology of the Cell 26, no. 6 (March 15, 2015): 1174–87. http://dx.doi.org/10.1091/mbc.e14-08-1312.
Повний текст джерелаMoreno-Ruiz, Dubraska, Linda Salzmann, Mark Fricker, Susanne Zeilinger, and Alexander Lichius. "Stress-Activated Protein Kinase Signalling Regulates Mycoparasitic Hyphal-Hyphal Interactions in Trichoderma atroviride." Journal of Fungi 7, no. 5 (May 6, 2021): 365. http://dx.doi.org/10.3390/jof7050365.
Повний текст джерелаMin, Kyunghun, Thomas F. Jannace, Haoyu Si, Krishna R. Veeramah, John D. Haley, and James B. Konopka. "Integrative multi-omics profiling reveals cAMP-independent mechanisms regulating hyphal morphogenesis in Candida albicans." PLOS Pathogens 17, no. 8 (August 16, 2021): e1009861. http://dx.doi.org/10.1371/journal.ppat.1009861.
Повний текст джерелаPulver, Rebecca, Timothy Heisel, Sara Gonia, Robert Robins, Jennifer Norton, Paula Haynes, and Cheryl A. Gale. "Rsr1 Focuses Cdc42 Activity at Hyphal Tips and Promotes Maintenance of Hyphal Development in Candida albicans." Eukaryotic Cell 12, no. 4 (December 7, 2012): 482–95. http://dx.doi.org/10.1128/ec.00294-12.
Повний текст джерелаMartin, Stephen W., and James B. Konopka. "Lipid Raft Polarization Contributes to Hyphal Growth in Candida albicans." Eukaryotic Cell 3, no. 3 (June 2004): 675–84. http://dx.doi.org/10.1128/ec.3.3.675-684.2004.
Повний текст джерелаBensen, Eric S., Scott G. Filler, and Judith Berman. "A Forkhead Transcription Factor Is Important for True Hyphal as well as Yeast Morphogenesis in Candida albicans." Eukaryotic Cell 1, no. 5 (October 2002): 787–98. http://dx.doi.org/10.1128/ec.1.5.787-798.2002.
Повний текст джерелаДисертації з теми "HYPHAL MORPHOGENESIS"
Laissue, P. P. "Morphogenesis of a filamentous fungus : dynamics of the actin cytoskeleton and control of hyphal integrity in Ashbya gossypii." Thesis, University of Kent, 2004. https://kar.kent.ac.uk/12170/.
Повний текст джерелаChapa, y. Lazo Bernardo. "Molecular biology of morphogenesis in Candida albicans : Cln3 has a role in the regulation of the cell cycle and hyphal growth, and Nap1 is required for septin ring fomation only in hyphae." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425620.
Повний текст джерелаMurad, Abdul Munir Abdul. "The role of NRG1 in the control of cellular morphogenesis in Candida albicans." Thesis, University of Aberdeen, 2001. http://digitool.abdn.ac.uk/R?func=search-advanced-go&find_code1=WSN&request1=AAIU602288.
Повний текст джерелаLacroix, Céline. "Nrg1p and Rfg1p in Candida albicans yeast-to-hyphae transition." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=112528.
Повний текст джерелаWang, Chih-Li. "Assessing the Roles of Striatin Orthologs in Fungal Morphogenesis, Sexual Development and Pathogenicity." Thesis, 2011. http://hdl.handle.net/1969.1/ETD-TAMU-2011-08-9935.
Повний текст джерелаDWIVEDI, PRAVEEN KUMAR. "CHARACTERIZATION OF EFFECTS OF FORMULATED PLANT EXTRACTS (NUTMEG AND PEPPER) ON HYPHAL MORPHOGENESIS IN CANDIDA ALBICANS." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/15536.
Повний текст джерелаSINGH, ANJU LATA. "CHARACTERIZATION OF EFFECTS OF SILVER NANOPARTICLES ON HYPHAL MORPHOGENESIS IN AN OPPORTUNISTIC FUNGAL PATHOGEN CANDIDA ALBICANS." Thesis, 2016. http://dspace.dtu.ac.in:8080/jspui/handle/repository/15155.
Повний текст джерелаShareck, Julie. "Effect of fatty acids on hyphal growth in the pathogenic yeast Candida albicans." Thèse, 2011. http://hdl.handle.net/1866/5494.
Повний текст джерелаThe yeast Candida albicans is an inhabitant of the oral cavity, the gastrointestinal and genitourinary tracts of humans. Generally encountered as a commensal, it is also an opportunistic pathogen that causes a spectrum of infections, ranging from superficial mycoses (thrush, vulvovaginitis) to severe and life-threatening systemic infections. A striking feature of C. albicans is its ability to grow in different morphological forms, including budding yeasts, pseudohyphae, and hyphae. Environmental cues that mimic host conditions (elevated temperature, neutral or alkaline pH, and serum) induce the yeast-to-hypha transition. Morphogenesis is considered to be an attribute of pathogenesis, as mutants locked as yeasts or filamentous forms are avirulent. Given that the yeast-to-hypha transition is a virulence factor, it may also constitute a target for the development of antifungal drugs. Indeed, evidence has shown that impairing morphogenesis is a means to treat systemic candidiasis. Concurrently, a number of molecules have been reported to modulate morphogenesis in C. albicans. For instance, several fatty acids, including conjugated linoleic acid (CLA), inhibited the yeast-to-hypha transition. By interfering with an important attribute of C. albicans pathogenesis, CLA may harbor antifungal properties. However, before assessing its therapeutic potential in a clinical context, it is mandatory to address CLA’s mode of action. The present study aims to further characterize the hypha-inhibiting properties of fatty acids and CLA and to elucidate the mechanism by which these molecules inhibit the yeast-to-hypha transition in C. albicans. Gene expression analyses were performed to gain insight into the transcriptional response of cells to CLA on a genome-wide scale and to probe the fatty acid’s mode of action. CLA downregulated the expression of hypha-specific genes and blocked the induction of genes encoding regulators of hyphal growth, including that of RAS1, which encodes the small GTPase Ras1p. A membrane-associated signaling protein, Ras1p plays a major role in morphogenesis. Quantitative PCR analyses showed that CLA prevented the increase in RAS1 mRNA levels which occurred at the onset of the yeast-to-hypha transition. Unexpectedly, CLA reduced the steady-state levels of Ras1p. Additionally, CLA caused the delocalization of GFP-Ras1p from the plasma membrane. These findings indicate that CLA treatment results in suboptimal Ras1p cellular concentrations and localization, which impedes Ras1p signaling and inhibits the yeast-to-hypha transition. CLA may indirectly affect Ras1p localization by altering the structure of the plasma membrane. These studies have provided the mechanism underlying CLA’s hypha-inhibiting properties and may serve as the rationale to examine CLA’s therapeutic potential in the context of a Candida infection. There is a general lack of clinical evidence demonstrating that impairing morphogenesis is a sound approach to treat candidiasis. To remedy this situation, the therapeutic potential of molecules that modulate morphogenesis, such as CLA, should be clinically assessed.
Klengel, Torsten. "Molekulare Charakterisierung der Carboanhydrase Nce103 im Kontext des CO2 induzierten Polymorphismus in Candida albicans." Doctoral thesis, 2008. https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-34573.
Повний текст джерелаDetection of environmental signals and subsequently directed reaction is essential for the survival of all living organisms. Candida albicans, as the predominant human fungal pathogen is exposed to severely different physical and chemical conditions, which influence cell morphology as well as virulence in human. In the present work, the influence of carbon dioxide as ubiquitous gaseous molecule on virulence and cell morphology was analysed. Elevated concentrations of carbon dioxide are a robust signal to induce the morphological transition from yeast growth to an elongated hyphal growth form, which is believed to be one of the main virulence factors in Candida albicans. The role of the putative carbonic anhydrase Nce103p in carbon dioxide signalling is reviewed by generating knockout mutant strains, which exhibited a carbon dioxide dependent phenotype. Growth under aerobic conditions (0,033 % carbon dioxide) is inhibited but feasible in 5% carbon dioxide. Therefore, Nce103p is essential for growth in host niches with aerobic conditions. Analysis of the biochemical properties of Nce103p by stopped – flow kinetics revealed carbonic anhydrase activity. It is hypothesised, that Nce103p is essential for fixation of carbon dioxide and bicarbonate within the cell in order to sustain basic metabolic reactions. Furthermore, the induction of hyphal growth was independent of aquaporine-mediated transport of carbon dioxide. Bicarbonate rather carbon dioxide activates directly the adenylyl cyclase Cdc35p generating cyclic AMP as second messenger and influencing the transcription of hyphal specific genes in Candida albicans thus promoting the morphological transition from yeast growth to elongated hyphal growth. This signal transduction cascade is present in Candida albicans as well as Cryptococcus neoformans and it is believed to be a pan fungal signal transduction cascade. The specific inhibition of carbon dioxide mediated polymorphism may serve as a new target for antifungal therapeutic agents
Частини книг з теми "HYPHAL MORPHOGENESIS"
Sietsma, J. H., C. A. Vermeulen, and J. G. H. Wessels. "The Role of Chitin in Hyphal Morphogenesis." In Chitin in Nature and Technology, 63–69. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2167-5_9.
Повний текст джерелаHoriuchi, Hiroyuki, and Takuya Katayama. "Protein Kinase C of Filamentous Fungi and Its Roles in the Stresses Affecting Hyphal Morphogenesis and Conidiation." In Stress Biology of Yeasts and Fungi, 185–98. Tokyo: Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-55248-2_12.
Повний текст джерела"Metabolism and Biochemistry of Hyphal Systems." In Fungal Morphogenesis, 71–133. Cambridge University Press, 1998. http://dx.doi.org/10.1017/cbo9780511529887.004.
Повний текст джерела"The Genetic Component of Hyphal Differentiation." In Fungal Morphogenesis, 191–245. Cambridge University Press, 1998. http://dx.doi.org/10.1017/cbo9780511529887.006.
Повний текст джерела"Hyphal Morphogenesis in Aspergillus nidulans." In The Aspergilli, 231–42. CRC Press, 2007. http://dx.doi.org/10.1201/9781420008517-20.
Повний текст джерелаHarris, Steven. "Hyphal Morphogenesis in Aspergillus nidulans." In Mycology, 211–22. CRC Press, 2007. http://dx.doi.org/10.1201/9781420008517.ch14.
Повний текст джерелаBARTNICKI-GARCIA, SALOMON. "Role of Vesicles in Apical Growth and a New Mathematical Model of Hyphal Morphogenesis." In Tip Growth In Plant and Fungal Cells, 211–32. Elsevier, 1990. http://dx.doi.org/10.1016/b978-0-12-335845-5.50011-2.
Повний текст джерела"Hypal Growth." In Fungal Morphogenesis, 26–70. Cambridge University Press, 1998. http://dx.doi.org/10.1017/cbo9780511529887.003.
Повний текст джерелаFallacara, Giuseppe, and Maurizio Barberio. "Parametric Morphogenesis, Robotic Fabrication, and Construction of Novel Stereotomic Hypar Morphologies." In Advances in Media, Entertainment, and the Arts, 329–53. IGI Global, 2018. http://dx.doi.org/10.4018/978-1-5225-3993-3.ch016.
Повний текст джерелаТези доповідей конференцій з теми "HYPHAL MORPHOGENESIS"
Bracker, Charles E., Douglas J. Murphy, and Rosamaria Lopez-Franco. "Laser microbeam manipulation of cell morphogenesis growing in fungal hyphae." In BiOS '97, Part of Photonics West, edited by Daniel L. Farkas and Bruce J. Tromberg. SPIE, 1997. http://dx.doi.org/10.1117/12.274325.
Повний текст джерелаЗвіти організацій з теми "HYPHAL MORPHOGENESIS"
Dickman, Martin B., and Oded Yarden. Regulation of Early Events in Hyphal Elongation, Branching and Differentiation of Filamentous Fungi. United States Department of Agriculture, 2000. http://dx.doi.org/10.32747/2000.7580674.bard.
Повний текст джерелаDickman, Martin B., and Oded Yarden. Phosphorylative Transduction of Developmental and Pathogenicity-Related Cues in Sclerotinia Sclerotiorum. United States Department of Agriculture, April 2004. http://dx.doi.org/10.32747/2004.7586472.bard.
Повний текст джерелаDickman, Martin B., and Oded Yarden. Modulation of the Redox Climate and Phosphatase Signaling in a Necrotroph: an Axis for Inter- and Intra-cellular Communication that Regulates Development and Pathogenicity. United States Department of Agriculture, August 2011. http://dx.doi.org/10.32747/2011.7697112.bard.
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