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Дисертації з теми "Human Immunological aspects"

Автор: Grafiati

Опубліковано: 4 червня 2021

Оновлено: 2 лютого 2022

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1

Ramshaw, Anna Louise. "Immunological aspects of human atherosclerosis." Thesis, University of Oxford, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.305549.

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2

Norbeck, Oscar. "Clinical and immunological aspects of human parvovirus B19 infection /." Stockholm : Dept. of laboratory medicine, Karolinska institutet, 2005. http://diss.kib.ki.se/2005/91-7140-203-9/.

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3

Wu, Yuet, and 吳越. "Immune response of human monocyte-derived dendritic cells to co-infection of influenza virus and Streptococcus pneumoniae." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B45543732.

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4

Yip, Ming-shum, and 葉名琛. "Severe acute respiratory syndrome coronavirus infection of human immune cells through antibody-mediated pathway." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46542139.

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5

Qin, Gang, and 秦刚. "The immunological roles of human gammadelta T lymphocytes in influenzavirus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B46477354.

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6

Yip, Ming-shum, and 葉名琛. "Immune responses of human respiratory epithelial cells to respiratory syncytial virus and human metapneumovirus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B3955725X.

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7

Yuan, Tingting, and 袁婷婷. "Identification of intermediate antibodies of broadly neutralizing HIV-1 human monoclonal antibody b12 and characterization of variable loops of HIV-1 envelop glycoprotein." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/196445.

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8

Yim, Chi-ho Howard, and 嚴志濠. "Cytokine dysregulation by human immunodeficiency virus-1 transactivating protein." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B36987700.

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9

Lu, Qian, and 陸茜. "Expression and regulation of human {221}-defensins in gingival epithelia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B36613708.

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10

Lee, Jai-Wei 1970. "The effect of recombinant human interleukin-1b and interleukin-8 on bovine neutrophil migration and degranulation /." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=21587.

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Анотація:

The objective of this study was to investigate the effect of recombinant human interleukin-1beta (rHIL-1beta) and interleukin-8 (rHIL-8) on bovine neutrophil migration and degranulation. An in vitro co-culture system was used to study bovine neutrophil migration. This simulative system allowed studying neutrophil migration across endothelium (bovine aorta endothelial cells), extracellular matrix (ECM), and epithelium (MAC-T) in the correct sequences and directions. Quantification of neutrophil migration was carried out by assaying the activity of myeloperoxidase, a major enzyme of neutrophils.

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11

Glinsmann-Gibson, Betty Jean 1961. "Molecular mechanism of autocrine regulation by TGF-alpha in T(3)M(4) human pancreatic carcinoma cells." Thesis, The University of Arizona, 1989. http://hdl.handle.net/10150/277113.

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The human pancreatic cancer cell line T3M4, is known to produce transforming growth factor-alpha (TGF-alpha); as well as overexpress the receptor for this ligand, epidermal growth factor (EGF) receptor. TGF-alpha messenger RNA (mRNA) levels were assayed using northern blot, after addition of epidermal growth factor or TGF-alpha. The level of TGF-alpha mRNA was found to increase 2-fold at 2 hours and then return to near basal levels at 10 hours, after treatment with either ligand. Both ligands were also equipotent in a 2 hour dose response assay, with half maximal stimulation seen at 1 nM and m

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12

Geary, Sean Michael. "Manipulation of the immunostimulatory capacity of a human myeloid leukaemia cell line HL-60 /." Title page, contents and abstract only, 1993. http://web4.library.adelaide.edu.au/theses/09PH/09phg292.pdf.

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13

Moller, Marlo. "Human genetic susceptibility to tuberculosis : the investigation of candidate genes influencing interferon gamma levels and other candidate genes affecting immunological pathways." Thesis, Stellenbosch : University of Stellenbosch, 2007. http://hdl.handle.net/10019.1/1264.

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Thesis (PhD (Biomedical Sciences. Molecular Biology and Human Genetics))--University of Stellenbosch, 2007.<br>The infectious disease tuberculosis (TB) is one of the leading causes of death worldwide. The idea that infectious diseases are the most important driving force in natural selection and that they sustain frequent polymorphisms in the human genome was formally suggested by Haldane in 1949. This hypothesis implicated the human genetic component in the response to infectious disease. Today the involvement of host genetics in TB has been proven unequivocally and, together with enviro

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14

Varelias, Antiopi. "Studies of CD44 variant isoform expression and function on activated human peripheral blood mononuclear cells and in renal transplantation." Title page, summary and contents only, 2001. http://web4.library.adelaide.edu.au/theses/09PH/09phv293.pdf.

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15

Reuter, Helmuth. "The immunopathogenesis and treatment of tuberculous pericardial effusions in a population with a high prevalence of infection with the human immunodeficiency virus." Thesis, Link to the online version, 2005. http://hdl.handle.net/10019.1/1411.

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16

Main, Carey Anne. "To determine the relationship between dietary intake, body composition and incidence of upper respiratory tract infections in triathletes during training and competition for the Ironman." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/80006.

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Thesis (MNutr)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: Background: The Ironman® triathlon is an ultra-endurance event. It has previously been shown that heavy training schedules and racing ultra-endurance events can lead to immune impairment. Evidence supporting the potential role of dietary intake and body composition on immune impairment or upper respiratory tract infections (URTIs) is currently lacking. Aim: To investigate the relationship between dietary intake, body composition and the incidence of URTI in triathletes residing in Port Elizabeth (PE), during training and

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17

Ali, Magdi Mahmoud. "Immunologic aspects of the pathogenesis of human onchocerciasis." Doctoral thesis, Stockholm University, Wenner-Gren Institute for Experimental Biology, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-793.

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<p>Onchocerciasis, or river blindness, is a parasitic disease that affects more than 20 million people globally. The induction of pathology is directly related to the presence and destruction of the microfilarial stages (mf) of this filarial nematode. The disease presents clinically with a wide spectrum of dermal and ocular manifestations, the basis of the variation is believed to involve the immune system. The clinical presentations of infected hosts relate to the intensity of the reactions against the parasite. Anti-microfilarial drugs are also thought to somehow involve the immune system in

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18

Ali, Magdi Mahmoud M. "The immunologic aspects of the pathogenesis of human onchocerciasis /." Stockholm : Dept. of immunology, Wenner-Gren institute, Stockholm university, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-793.

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19

Bekele, Adane Mihret. "Gene expression and cytokine pattern of pulmonary tuberculosis patients and their contacts in Ethiopia." Thesis, Stellenbosch : Stellenbosch University, 2012. http://hdl.handle.net/10019.1/71942.

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Thesis (PhD)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: The immune response against M. tuberculosis is multifactorial, involving a network of innate and adaptive immune responses. Characterization of the immune response, a clear understanding of the dynamics and interplay of different arms of the immune response and the identification of infection-stage specific biomarkers are critical to allow the development of better tools for combating tuberculosis. In an attempt to identify such biomarkers, we studied pulmonary tuberculosis patients and their contacts in Addis Ababa, Ethio

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20

Gutschmidt, Andrea. "Evaluation of anti-tuberculosis responses in humans using different complementary immunological techniques." Thesis, Stellenbosch : Stellenbosch University, 2013. http://hdl.handle.net/10019.1/79835.

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Thesis (MSc MedSc)--Stellenbosch University, 2013.<br>ENGLISH ABSTRACT: Background The QuantiFERON In-Tube (QFT IT) assay is an Interferon-gamma release assay (IGRA) which is currently used to detect Mycobacterium tuberculosis (M. tb) infection. It however cannot differentiate between latent infection and active tuberculosis (TB) disease. In an attempt to improve this tool to accurately diagnose active TB, the release of a variety of markers should be assessed in combination with Interferon gamma (IFN- γ). Luminex analysis was previously done on QFT plasma and promising candidates were

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21

Latis, Eleonora M. T. "Exploring immunological mechanisms of human graft-versus-host disease after hematopoietic stem cell transplantation." Thesis, Sorbonne Paris Cité, 2018. https://theses.md.univ-paris-diderot.fr/LATIS_Eleonora_va.pdf.

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L’allogreffe de cellules souches hématopoïétiques est un traitement curatif pour de nombreuses maladies hématologiques. Cependant, le succès de cette procédure est entravé par la maladie du Greffon-contre-l’Hôte (GVH), une complication potentiellement fatale induite par l’attaque des tissues de l’hôte par les cellules T alloreactives du donneur. La GVH a une prévalence de 40 à 80%, selon les caractéristiques de la transplantation. La GVH est la cause principale de mortalité post-greffe en dehors des rechutes et, en dépit des nombreuses avancées dans le domaine de l’allogreffe, la physiopatholo

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22

Dauby, Nicolas. "Réponse des lymphocytes B lors de l'infection primaire au cytomégalovirus humain pendant la grossesse." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209097.

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L'infection par le cytomégalovirus humain (HCMV) est une cause majeure de mortalité chez les patients immunodéprimés et représente la première cause d'infection congénitale. HCMV est un virus complexe qui s'est adapté au système immunitaire humain en développant de multiples mécanismes d'évasion. L'infection primaire à HCMV est associée à une réplication virale prolongée avant l'établissement de la latence. Il a été montré que cette intense réplication lors de la phase initiale de l'infection était associée à une épuisement fonctionnel des lymphocytes T CD4 spécifiques du virus. Alors que les

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23

Lyons, A. B. "Human myeloid differentiation antigens / Alan Bruce Lyons." 1987. http://hdl.handle.net/2440/21575.

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Bibliography: leaves 154-185<br>iv, 185 leaves, [15] leaves of plates : ill. (some col.) ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Science, 1987

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24

Kramer, Kenton Jay. "A seroepidemiological study of human antibodies to the major merozoite surface coat precursor protein of Plasmodium falciparum (GP195) from a hyperendemic area of the Philippines." Thesis, 1990. http://hdl.handle.net/10125/9444.

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25

Byrd, Daniel James. "Vaccinia Virus Binding and Infection of Primary Human Leukocytes." Thesis, 2014. http://hdl.handle.net/1805/5279.

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Indiana University-Purdue University Indianapolis (IUPUI)<br>Vaccinia virus (VV) is the prototypical member of the orthopoxvirus genus of the Poxviridae family, and is currently being evaluated as a vector for vaccine development and cancer cell-targeting therapy. Despite the importance of studying poxvirus effects on the human immune system, reports of the direct interactions between poxviruses and primary human leukocytes (PHLs) are limited. We studied the specific molecular events that determine the VV tropism for major PHL subsets including monocytes, B cells, neutrophils, NK cells, and T

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26

Leibelt, Dustin A. "Chronic exposure of rodents to indole-3-carbinol and 3,3'-diindolylmethane : implications for drug metabolism, chemoprevention and human health." Thesis, 2003. http://hdl.handle.net/1957/31050.

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Indole-3-carbinol (I3C) is a naturally occurring plant alkaloid, found in significant concentrations in cruciferous vegetables such as broccoli and Brussels sprouts. I3C is an unstable compound that undergoes rapid oligomerization in an acidic environment to form higher order condensation products (I3C-ACPs), such as 3-3'-diindolylmethane (DIM). Both I3C and DIM are marketed as dietary supplements and are under investigation as potential chemopreventive agents, despite limited data on the effects of chronic exposure. Previous studies have demonstrated that the chemopreventive potential of I3C

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27

"Immunoregulatory role of human islet amyloid polypeptide through FoxP3+CD4+CD25+ T regulatory cells." Thesis, 2010. http://library.cuhk.edu.hk/record=b6075044.

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Background. Islet amyloid polypeptide (IAPP, also known as amylin) is a 37-amino acid peptide principally co-secreted with insulin from the beta-cells of the pancreatic islets. Some of the physiological actions of human amylin (hIAPP) include glucose regulation, suppression of appetite and stimulation of renal sodium and water reabsorption. Amylin deficiency and diminished post-prandial amylin response have been reported in advanced stages of type 1 and type 2 diabetes. In autopsy specimens of type 2 diabetes, amyloid is found in 40--90% of cases. During the characterization of islet morpholog

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28

Yirdaw, Kesetebirhan Delele. "Prevalence and predictors of immunologic failure among HIV patients on HAART in southern Ethiopia." Diss., 2014. http://hdl.handle.net/10500/18970.

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Immunologic monitoring is part of the standard care for patients on antiretroviral treatment. Yet, little is known about the routine implementation of immunologic monitoring in Ethiopia. This study assessed the pattern of immunologic monitoring, immunologic response, level of immunologic treatment failure and factors related to it among patients on antiretroviral therapy in selected hospitals in southern Ethiopia. A retrospective longitudinal analytic study was conducted using documents of patients started on antiretroviral therapy. A total of 1,321 documents of patients reviewed revealed tim

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29

Monyai, Florina Semakaleng. "Establishment of interaction partners of Plasmodium falciparum heat shock protein 70-x(PfHsp 70-x)." Diss., 2018. http://hdl.handle.net/11602/1113.

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MSc (Biochemistry)<br>Department of Biochemistry<br>Plasmodium falciparum is a unicellular protozoan parasite that causes malaria in humans. The parasite is passed to humans through mosquito bites and migrates to the liver before it infects host erythrocytes. It is at the erythrocytic stage of development that the parasite causes malaria pathology. Malaria is characterized by the modification of host erythrocytes making them cytoadherent. This is as a result of formation of protein complexes (knobs) on the surface of the erythrocyte. The knobs that develop on the surface of the erythrocyte are

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30

Madisha, Mpho Christa Judith. "Factors altering HIV and Aids postnatal clients' commitment to exclusive breastfeeding." Diss., 2008. http://hdl.handle.net/10500/2952.

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The study sought to explore and describe the breastfeeding practices of Human Immunodeficiency Virus (HIV) positive postnatal clients’ non-commitment to exclusive breastfeeding in George Mukhari Hospital, South Africa. A non-experimental quantitative design was used. Inferences drawn from the study were that HIV positive clients that opted for exclusive breastfeeding did not commit for fear of transmission of HIV to the baby and exclusive breastfeeding was stopped before the recommended 6 months. Most of the respondents’ partners did not come for counselling. There was lack of emotional suppo

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31

Shwetank, *. "Infection of Human Cell Lines by Japanese Encephalitis Virus : Increased Expression and Release of HLA-E, a Non-classical HLA Molecule." Thesis, 2013. http://etd.iisc.ernet.in/2005/3457.

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Japanese encephalitis virus (JEV) causes viral encephalitis in new born and young adults that is prevalent in different parts of India and other parts of South East Asia with an estimated 6000 deaths per year. JEV is a single stranded RNA virus that belongs to the Flavivirusgenus of the family Flaviviridae. It is a neurotropic virus which infects the central nervous system (CNS). The virus follows a zoonotic life-cycle involving mosquitoes and vertebrates, chiefly pigs and ardeid birds, as amplifying hosts. Humans are dead end hosts. After entry into the host following a mosquito bite, JEV inf

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32

Stuart, Melissa Kay. "A comparative study of serum antibody specificities and antigenic differences among strains as contributing factors to chronic infection with Giardia lamblia in humans." 1985. http://hdl.handle.net/2097/27552.

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