Дисертації з теми "Host - microbial interaction"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся з топ-21 дисертацій для дослідження на тему "Host - microbial interaction".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Переглядайте дисертації для різних дисциплін та оформлюйте правильно вашу бібліографію.
Yan, Shuangchun. "Using the Bacterial Plant Pathogen Pseudomonas syringae pv. tomato as a Model to Study the Evolution and Mechanisms of Host Range and Virulence." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/77293.
Повний текст джерелаPh. D.
Phetcharaburanin, Jutarop. "Gut microbial-host metabolic interactions following bariatric surgery." Thesis, Imperial College London, 2018. http://hdl.handle.net/10044/1/61845.
Повний текст джерелаHanage, William Paul. "Host microbial interactions in the pathogenesis of Viridans streptococcal septic shock." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272512.
Повний текст джерелаLandrygan-Bakri, Janine. "Host-microbial interactions and cellular reponses associated with 'Streptococcus anginosus' group infection." Thesis, Cardiff University, 2007. http://orca.cf.ac.uk/55625/.
Повний текст джерелаSanguino, Casado Laura. "Exploration des interactions virus-hôte et leur importance pour l'adaptation microbienne à travers du CRISPRs." Thesis, Ecully, Ecole centrale de Lyon, 2015. http://www.theses.fr/2015ECDL0033/document.
Повний текст джерелаInteractions between the members of a microbial community can be a means of adaptation in the environment. Among the many interactions that take place in an ecosystem and have been seen to play a major role on microbial diversity and population dynamics is that of prokaryotic viruses and their hosts. Viruses can also mediate the transfer of genetic material between prokaryotes (transduction), which could be a mechanism for rapid adaptation. In order to determine the potential impact of viruses and transduction, we need a better understanding of the dynamics of interactions between viruses and their hosts in the environment. Data on environmental viruses are scarce, and methods for tracking their interactions with prokaryotes are needed. Clustered regularly interspaced short palindromic repeats (CRISPRs), which contain viral sequences in bacterial genomes, might help document the history of virus-host interactions in the environment. Thus, this thesis aimed to explore virus-host interactions in a given environment through CRISPRs. Viruses in the cryosphere have been seen to be abundant, highly active and with broad host ranges. These characteristics could make viral transduction a key driver of adaptation in these environments. Public metagenomes created from environments over a range of temperatures were examined through sequence and CRISPR analysis. In this fashion, certain virus-host interaction dynamics were found to have a correlation with temperature. A workflow was then developed to create a network linking viruses and their hosts using CRISPR sequences obtained from metagenomic data from Arctic glacial ice and soil. The creation of CRISPR-based infection networks provided a new perspective on virus-host interactions in glacial ice. Moreover, we searched for transduction events in metagenomic data by looking for viral sequences containing microbial DNA. Further analysis of the viral sequences in the CRISPRs indicated that Ralstonia phages might be agents of transduction in Arctic glacial ice
Tujulin, Eva. "Host interactions of the intracellular bacterium Coxiella burnetii : internalisation, induction of bacterial proteins and host response upon infection /." Uppsala : Swedish Univ. of Agricultural Sciences (Sveriges lantbruksuniv.), 1999. http://epsilon.slu.se/avh/1999/91-576-5425-5.pdf.
Повний текст джерелаAustin, Andrew Simon. "CD14, toll-like receptors and host-microbial interactions in portal hypertension and inflammatory bowel disease." Thesis, University of Nottingham, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410409.
Повний текст джерелаChella, Krishnan Karthickeyan. "Host-Pathogen Interactions Promoting Pathogen Survival and Potentiating Disease Severity & Morbidity in Invasive Group A Streptococcal Necrotizing Soft Tissue Infections." University of Cincinnati / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1446546952.
Повний текст джерелаKaßler, Kristin [Verfasser], and Heinrich [Akademischer Betreuer] Sticht. "Exploring Stability, Dynamics and Interactions of Microbial Effectors and Host Proteins: A Computational Approach / Kristin Kaßler. Betreuer: Heinrich Sticht." Erlangen : Universitätsbibliothek der Universität Erlangen-Nürnberg, 2013. http://d-nb.info/1037020618/34.
Повний текст джерелаDriscoll, Timothy. "Host-Microbe Relations: A Phylogenomics-Driven Bioinformatic Approach to the Characterization of Microbial DNA from Heterogeneous Sequence Data." Diss., Virginia Tech, 2013. http://hdl.handle.net/10919/50921.
Повний текст джерелаPh. D.
Lee, Sungeun. "Virus-host interactions across a soil pH gradient at the community and individual scale." Thesis, Lyon, 2020. http://www.theses.fr/2020LYSEC020.
Повний текст джерелаSoil viruses have potential to influence microbial community structure and subsequent ecosystem functioning by directly affecting the abundance of host cells by lysis and through their ability to transfer genes between hosts. Although our understanding of soil viral diversity and functioning has increased, the role of viruses and their interactions with prokaryotes in soil is limited. To gain a better understanding of virus-host interactions in soil, a long-term pH-manipulated soil gradient, which microbial community structure changes across, was investigated. The main objectives of this thesis were to 1) determine the influence of microbial community structure and soil pH on viruses using metagenomics and viromics (Chapter II), 2) determine the infectivity of soil viral populations from co-localized and foreign pH soil niches using a plaque assay approach combined with hybrid metagenomics sequencing (Chapter III) and 3) identify virus populations infecting specific soil microbial functional groups, specifically methanotrophs (Chapter IV) and nitrifiers (Chapter V), using DNA stable isotope probing combined with metagenomic deep sequencing. Viral community structure was found to change with soil pH, demonstrating that viral communities are tightly linked to host populations, but also may have narrow host ranges. Analysis of clustered regularly interspaced short palindromic repeats (CRISPR) arrays revealed dynamic virus-host interactions, with the number and size of CRISPR arrays distinct across contrasting pH soil. Profiling of the host-virus linkages between soil pH, suggests that viruses play a critical role in shaping the composition and function of the soil prokaryotic community. Surprisingly, greater infectivity of a host bacterium by virus populations was found when viruses and host bacterium were not co-localized in the same pH soil. Coevolutionary processes between the host and virus populations, such as restriction modification/virus-encoded methyltransferase and CRISPR-Cas system/spacer mutation, provide evidence for local adaptation, and that virus-bacterial host interactions play an integral part in the susceptibility of a host to infection and consequently in the regulation of soil bacterial populations. Targeting specific microbial functional groups via stable isotope probing allowed analysis of individual host-virus populations. Tracking carbon flow through prokaryotic and viral populations revealed active interactions between viruses and methanotroph and nitrifier hosts, and soil pH niche preferences. Evidence of horizontal gene transfer and virus-encoded auxiliary metabolic genes, such as glycoside hydrolase families, peptidases, particulate methane monooxygenase subunit C (pmoC), nitrogenase (nifH) and cytochrome cd1-nitrite reductase, supports that viruses are significant contributors to host functioning and carbon and nitrogen cycling in soil. Overall, this work demonstrated that soil viruses are important regulators of microbial communities through specific host lysis and dynamic virus-host interactions
Bergamo, Estrela Andréia [Verfasser], and Kenneth N. [Akademischer Betreuer] Timmis. "Host-microbial interactions: extracellular metabolites with immunomodulatory potential generated by Escherichia coli in response to human defensin / Andréia Bergamo Estrela ; Betreuer: Kenneth N. Timmis." Braunschweig : Technische Universität Braunschweig, 2011. http://d-nb.info/1175825182/34.
Повний текст джерелаDelafont, Vincent. "Diversité et implication des amibes libres dans la survie et la persistance des mycobactéries non tuberculeuses au sein d'un réseau d'eau potable." Thesis, Poitiers, 2015. http://www.theses.fr/2015POIT2278/document.
Повний текст джерелаFree-living amoebae are unicellular eukaryotes whose ecology in drinking water networks remains poorly understood. They may represent a public health concern, because of their ability to favour the presence of potentially pathogenic bacteria, among which are mycobacteria.A sampling scheme based on Paris drinking water network allowed identifying the diversity of both freeliving amoebae and their bacterial microbiome, using ribosomal RNA targeted pyrosequencing. These analyses indicated the major presence of Acanthamoeba, Vermamoeba, Echinamoeba and Protacanthamoeba genera. The microbiome was highly diverse and dominated by Pseudomonas, Stenotrophomonas, Bradyrhizobium, Sphingomonas and Pseudoxanthomonas. The coupling of physicochemical parameters to this analysis allowed underlining the importance of water origin, temperature, pH and chlorine concentration in shaping amoebal populations. Also an original endosymbiosis between V. vermiformis and a bacterium of the TM6 phylum was described. Free-living amoebae were frequently co-isolated with mycobacteria in the water network, mainly M. llatzerense and M. chelonae species. Infection experiments on A. castellanii illustrated the capacity of these species to resist and grow in presence of amoebae. Through genomics and transcriptomics approaches, several virulence factors, conserved between M. llatzerense, M. chelonae and M. tuberculosis were identified, and found to be upregulated during infection experiments. These results suggest their involvement in mycobacterial resistance to amoebal predation.Altogether, this work helped to better understand the ecology of free-living amoebae and their microbiome in drinking water networks, as well as the role of free-living amoebae in the survival and persistence of mycobacteria in such environments
Partula, Valentin. "A nutritional epidemiology study of human gut microbiota - Associations with the systemic metabolism and usual diet of the host and relationships between dietary fibers and the host’s health." Thesis, Université de Paris (2019-....), 2019. http://www.theses.fr/2019UNIP7119.
Повний текст джерелаIt is now admitted that the gut microbiota plays a key role in the health status of its human host. It is indeed fully recognized as an endocrine organ producing biologically active molecules which are integrated within human metabolism. However, comprehensive studies characterizing host-gut microbial metabolic relationships remain scarce. Numerous factors have been shown to exert a modulatory impact on the gut microbiota. Notably, diet is supposed to be a major driver, but the relationships between usual diet and the gut microbiota are not fully elucidated yet. Furthermore, many studies have suggested the implication of the gut microbiota in a wide range of disease states, such as gastrointestinal, cardio-metabolic, neuropsychiatric, etc. disorders. Thus, understanding the factors influencing the gut microbiota constitutes an active area of research. In this context, we adopted an epidemiological approach to investigate one of the largest population-based samples so far (Milieu Intérieur population, N=1,000). We notably assessed the associations between gut microbiota composition on one hand and the systemic metabolism and the usual diet of the host on the other. Finally, in the NutriNet-Santé cohort (N≈160,000), we investigated the associations between the intake of dietary fibers and the risk of a variety of chronic diseases, and described how dietary fibers are associated with the gut microbiota.Overall, our results suggest that gut bacterial features are specifically associated with certain components of the systemic metabolism of the host, and we hypothesize a substantial role of the gut-kidney axis. Besides, negative associations between food items for which a limited consumption is generally recommended (i.e. processed foods) and gut microbial features were detected. Additionally, we confirm robust inverse associations between the consumption of dietary fibers and several major chronic diseases. Mounting evidence suggests that such effects could be mediated by the gut microbiota
"Microbial Programming of the Neonatal Pig." Thesis, 2013. http://hdl.handle.net/10388/ETD-2013-07-1175.
Повний текст джерелаYadav, Preeti. "Studies on the regulatory roles for Retinoic Acid (RA) during host-microbial interaction : implications for S. aureus and C. albicans infections." Thesis, 2019. https://etd.iisc.ac.in/handle/2005/4520.
Повний текст джерелаDonato, Kevin. "Microbial-host Interactions and Modulation of Epithelial Barrier Function: Pathogens to Probiotics." Thesis, 2010. http://hdl.handle.net/1807/26168.
Повний текст джерелаNaick, Ravindra M. "Functional Insights into PRR-Driven SHH Signaling : Implications for Host-Microbial Interactions." Thesis, 2015. http://etd.iisc.ac.in/handle/2005/3883.
Повний текст джерелаNaick, Ravindra M. "Functional Insights into PRR-Driven SHH Signaling : Implications for Host-Microbial Interactions." Thesis, 2015. http://etd.iisc.ernet.in/2005/3883.
Повний текст джерелаHolmer, Stephanie. "The Impact of Surfactant Protein D, Interleukin‑5, and Eosinophilia on Cryptococcosis." Diss., 2013. http://hdl.handle.net/10161/8072.
Повний текст джерелаDissertation
(11186766), Geoffrey M. Williams. "Thousand Cankers Disease of Eastern Black Walnut: Ecological Interactions in the Holobiont of a Bark Beetle-Fungal Disease." Thesis, 2021.
Знайти повний текст джерелаEastern black walnut (Juglans nigra L.) ranks among the most highly valued timber species in the central hardwood forest and across the world. This valuable tree fills a critical role in native ecosystems as a mast bearing pioneer on mesic sites. Along with other Juglans spp. (Juglandaceae), J. nigra is threatened by thousand cankers disease (TCD), an insect-vectored disease first described in 2009. TCD is caused by the bark beetle Pityophthorus juglandis Blackman (Corthylini) and the phytopathogenic fungus Geosmithia morbida Kol. Free. Ut. & Tiss. (Bionectriaceae). Together, the P. juglandis-G. morbida complex has expanded from its historical range in southwest North America throughout the western United States (U.S.) and Europe. This range expansion has led to widespread mortality among naïve hosts J. nigra and J. regia planted outside their native distributions.
The severity of TCD was previously observed to be highest in urban and plantation environments and outside of the host native range. Therefore, the objective of this work was to provide information on biotic and abiotic environmental factors that influence the severity and impact of TCD across the native and non-native range of J. nigra and across different climatic and management regimes. This knowledge would enable a better assessment of the risk posed by TCD and a basis for developing management activities that impart resilience to natural systems. Through a series of greenhouse-, laboratory- and field-based experiments, environmental factors that affect the pathogenicity and/or survival of G. morbida in J. nigra were identified, with a focus on the microbiome, climate, and opportunistic pathogens. A number of potentially important interactions among host, vector, pathogen and the rest of the holobiont of TCD were characterized. The holobiont is defined as the whole multitrophic community of organisms—including J. nigra, microinvertebrates, fungi and bacteria—that interact with one another and with the host.
Our findings indicate that interactions among host, vector, pathogen, secondary pathogens, novel microbial communities, and novel abiotic environments modulate the severity of TCD in native, non-native, and managed and unmanaged contexts. Prevailing climatic conditions favor reproduction and spread of G. morbida in the western United States due to the effect of wood moisture content on fungal competition. The microbiome of soils, roots, and stems of trees and seedlings grown outside the host native range harbor distinct, lower-diversity communities of bacteria and fungi compared to the native range, including different communities of beneficial or pathogenic functional groups of fungi. The pathogen G. morbida was also associated with a distinct community of microbes in stems compared to G. morbida-negative trees. The soil microbiome from intensively-managed plantations facilitated positive feedback between G. morbida and a disease-promomting endophytic Fusarium solani species complex sp. in roots of J. nigra seedlings. Finally, the nematode species Bursaphelenchus juglandis associated with P. juglandis synergizes with G. morbida to cause foliar symptoms in seedlings in a shadehouse; conversely, experiments and observations indicated that the nematode species Panagrolaimus sp. and cf. Ektaphelenchus sp. could suppress WTB populations and/or TCD outbreaks.
In conclusion, the composition, function, and interactions within the P. juglandis and J. nigra holobiont play important roles in the TCD pathosystem. Managers and conservationists should be aware that novel associations outside the host native range, or in monocultures, intensive nursery production, and urban and low-humidity environments may favor progression of the disease through the effects of associated phytobiomes, nematodes, and climatic conditions on disease etiology. Trees in higher diversity, less intensively managed growing environments within their native range may be more resilient to disease. Moreover, expatriated, susceptible host species (i.e., J. nigra) growing in environments that are favorable to novel pests or pest complexes (i.e., the western U.S.) may provide connectivity between emergent forest health threats (i.e., TCD) and native host populations (i.e., J. nigra in its native range).