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Статті в журналах з теми "HM-ECG"
1
Stepanets, E. A., D. P. Salivonchik, and V. P. Krupenin. "Comparative analysis of daily electrocardiogram monitoring recording using the “standard” and “optimized” techniques of electrode placement on the chest." Health and Ecology Issues 19, no. 1 (March 30, 2022): 27–34. http://dx.doi.org/10.51523/2708-6011.2022-19-1-04.
Повний текст джерелаАнотація:
Objective. To analyze a HM ECG recording in the placement of the electrodes in accordance with the procedure established by the manufacturer for the domestic recorder “Cardian-SDM” and in changed placement of the electrodes.Materials and methods. The study included 30 patients, the average age of the subjects was 34.7 ± 16.9 years, the median was 23 years, of which males accounted for 40 % (n = 12), females – 60 % (n = 18). When analyzing the HM ECG, the amplitude of the main ECG teeth, the displacement of the ST segment, and the change in the morphology of extrasystolic complexes were evaluated using the “standard” and “optimized” recording techniques. Such parameters as sensitivity and specificity of the proposed method were determined. The statistical analysis was carried out using the SPSS Statistics program.23 and Microsoft Excel.Results. During the automatic analysis of significant deviations in the amplitude of the ECG waves, rhythm disturbances, no ST segment changes were not registered when using the “optimized” technique compared to the “standard” one. The analysis of 30 HM ECG episodes taking into account the amplitude of the main teeth according to the “optimized” technique has a specificity of 93.4 % and sensitivity of 96.7 %, the deviation of the amplitude parameters has no significant differences, p > 0.05.Conclusion. The changes in the amplitude of the teeth did not exceed 10 %, the duration of the complexes, segments, and intervals did not change, p > 0.05. The specificity of the proposed “optimized” technique was 93.4 %, sensitivity – 96.7 %. The “optimized” technique can be used instead of the existing one to improve the quality of the ECG recorded in patients during physical exercise.
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Kalacheva, T. P., S. V. Fedosenko, O. A. Denisova, G. M. Chernyavskaya, T. M. Poponina, A. O. Naumov, I. A. Palchikova, G. V. Dudko, and M. A. Karnaushkina. "Clinical and functional features of the course of respiratory sarcoidosis in real practice." Russian Pulmonology 30, no. 2 (June 21, 2020): 204–12. http://dx.doi.org/10.18093/0869-0189-2020-30-2-204-212.
Повний текст джерелаАнотація:
As a rule, heart damage in patients with sarcoidosis of respiratory organs (SOD) is not diagnosed in time, so a very important and urgent task is to identify common heart rhythm and conduction disorders.The aim of the study was to investigate the main clinical manifestations of sarcoidosis in SOD, depending on the peculiarities of the disease course and to compare the frequency and severity of pulmonary and extrapulmonary manifestations of sarcoidosis, including myocardial lesions and electrocardiographic (ECG) signs of heart rhythm disorders.Methods. In the period 2006– 2016, the pilot open prospective uncontrolled study conducted at the Pulmonology Department of the Regional State Autonomous Healthcare Institution "Tomsk Regional Clinical Hospital" included patients (n = 84) aged 20–67 years with the diagnosis of SOD. Patients were divided into 2 clinical groups: the 1st comprised 45 (53.5%) patients with a favorable course of sarcoidosis, the second one included 39 (46.4%) patients with an unfavorable course of the disease. A full range of studies was carried out, including the analysis of medical history and clinical and epidemiological data, instrumental methods (including ECG and Holter ECG monitoring (HM), pathomorphological study of lung biopsy samples.Results. According to the data of frequency analysis of occurrence of pulmonary and extrapulmonary clinical manifestations in ODS, it was shown that the leading clinical manifestations, most frequently occurring in patients of both groups, included asthenia syndrome (72.6%), bronchial syndrome (66.7%) and fever syndrome (33%). In 33% of cases, clinical manifestations of myocardial damage were detected. In 41 (51.2%) patients in both groups, changes on ECG were recorded at rest. Regardless of the course of the disease, in 23.5% of patients of both clinical groups, according to the results of the HM ECG, rhythm and conduction disturbances were found – a combination of ventricular arrhythmias and conduction disorders (ventricular extrasystole and right His bundle branch block of various degrees) and a combination of supraventricular arrhythmias and conduction disturbances (supraventricular extrasystole and right His bundle branch block of various degrees).Conclusion. Thus, regardless of the severity of the disease course, SOD patients are concerned about complaints from both respiratory system and extrapulmonary manifestations, including cardiac complaints, as well as heart rhythm and conduction disorders (according to the results of ECG and HM ECG), the frequency of which, according to the comparative analysis, has not significantly changed in both clinical groups, which indicates the non-specific character of clinical manifestations.
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Frigy, Attila, Annamária Magdás, Victor-Dan Moga, Ioana Georgiana Coteț, Miklós Kozlovszky, and László Szilágyi. "Increase of Short-Term Heart Rate Variability Induced by Blood Pressure Measurements during Ambulatory Blood Pressure Monitoring." Computational and Mathematical Methods in Medicine 2017 (2017): 1–5. http://dx.doi.org/10.1155/2017/5235319.
Повний текст джерелаАнотація:
Objective.The possible effect of blood pressure measurements per se on heart rate variability (HRV) was studied in the setting of concomitant ambulatory blood pressure monitoring (ABPM) and Holter ECG monitoring (HM).Methods.In 25 hypertensive patients (14 women and 11 men, mean age: 58.1 years), 24-hour combined ABPM and HM were performed. For every blood pressure measurement, 2-minute ECG segments (before, during, and after measurement) were analyzed to obtain time domain parameters of HRV: SDNN and rMSSD. Mean of normal RR intervals (MNN), SDNN/MNN, and rMSSD/MNN were calculated, too. Parameter variations related to blood pressure measurements were analyzed using one-way ANOVA with multiple comparisons.Results.2281 measurements (1518 during the day and 763 during the night) were included in the analysis. Both SDNN and SDNN/MNN had a constant (the same for 24-hour, daytime, and nighttime values) and significant change related to blood pressure measurements: an increase during measurements and a decrease after them (p<0.01for any variation).Conclusion.In the setting of combined ABPM and HM, the blood pressure measurement itself produces an increase in short-term heart rate variability. Clarifying the physiological basis and the possible clinical value of this phenomenon needs further studies.
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Wang, Zheming, Elena A. Asafieva, and Tatiana I. Makeeva. "Predictive value of the N-terminal prohormone of brain natriuretic peptide in the long-term prognosis of ventricular arrhythmia in diabetic patients with acute coronary syndrome of young and middle age." Актуальные проблемы медицины 43, no. 4 (December 30, 2020): 522–38. http://dx.doi.org/10.18413/2687-0940-2020-43-4-522-538.
Повний текст джерелаАнотація:
The article investigates the prognostic value of pro-B-type N-terminal natriuretic peptide (NTproBNP) in connection with ventricular extrasystoles (VES) in a population of patients with diabetes mellitus with acute coronary syndrome (ACS) after successful coronary reperfusion by percutaneous coronary intervention (PCI). Patients with ACS were examined by defining biomarkers and performing echocardiography (EchoCG) on the first day of ACS after PCI with stenting of the infarction-related coronary artery, and Holter monitoring of electrocardiography (HM-ECG) on the second day after PCI; 12 months later, EchoCG, HM-ECG and NT-proBNP determination were repeated. It was found that the incidence of VES in the long-term prognosis among ACS patients with diabetes of young and middle age was more frequent than in patients without diabetes. A positive correlation was found between the NTproBNP level and ventricular arrhythmia in ACS patients with diabetes mellitus. It has been proven that a high level of NT-proBNP on the first day in patients with ACS after PCI as an independent indicator of risk to development of VES in long-term prognosis.
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Nekrasov, A. A., E. S. Timoshchenko, T. A. Nekrasova, M. V. Timoshchenko, and A. V. Suleimanova. "The effect of rivaroxaban low doses on the stable angina of the II–III functional class clinical manifestations and the quality of life in patients with ischemic heart disease." Kardiologiia 61, no. 9 (September 30, 2021): 47–51. http://dx.doi.org/10.18087/cardio.2021.9.n1696.
Повний текст джерелаАнотація:
Aim To evaluate the effect of low-dose rivaroxaban on quality of life of patients and clinical manifestations of functional class (FC) II-III stable angina.Material and methods 26 patients with ischemic heart disease (IHD) with FC II-III stable angina, who were newly prescribed rivaroxaban 2.5 mg twice a day in combination with acetylsalicylic acid 75-100 mg, were followed for 10 weeks. During the first (before the beginning of treatment) and the last weeks of study, patients kept diaries, in which they reported angina attacks and short-acting nitrate intake, filled in an angina questionnaire (SAQ), and underwent electrocardiogram (ECG) Holter monitoring (HM).Results The treatment was associated with decreases in the frequency of angina attacks (by 19.5 %; р=0.027) and the number of taken short-acting nitrate pills (by 17.1 %; р=0.021) and an improvement of quality of life according to stability scales (р=0.042). Data from ECG HM showed decreases in the number and duration of ischemic episodes (p≤0.05).Conclusion The treatment of IHD patients with rivaroxaban 2.5 mg twice a day in combination with acetylsalicylic acid 75-100 mg for 2 mos. was associated with decreased frequency of angina attacks, reduced requirement for short-acting nitrate, and with improvement of quality of life.
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Kurman, Michael R., Philip Sager, Marc S. Rudoltz, Joel Eisner, Daniel Goodman, Eugene Heyman, Daniel Salvail, Caroline Bell, and William R. Moore. "Cardiovascular safety profile of VT-464 in patients (pts) with castrate-resistant prostate cancer (CRPC)." Journal of Clinical Oncology 34, no. 2_suppl (January 10, 2016): 198. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.198.
Повний текст джерелаАнотація:
198 Background: VT-464 is a dual selective inhibitor of CYP17,20 lyase and an androgen receptor antagonist in development for the treatment of CRPC. In early clinical testing, several pts receiving VT-464 in 28-day cycles were noted to have syncopal, pre-syncopal or vaso-vagal episodes with typical prodromes. To further evaluate these events, Holter monitoring (HM) was performed in pts enrolled in two clinical studies. Methods: Continuous HM was performed at Screening, after the first dose of VT-464 C1D8, and C2D1 for study INO-VT-464-CL-001; and at Screening, after the first dose of VT-464, and C2D1 for study INO-VT-464-CL-004. The Screening visit HM data was considered the baseline. Plasma levels of VT-464 (in selected pts) and 12-lead ECGs of 10-seconds duration were extracted in triplicate for each pt from the HM data at Baseline, Day 1 and C2D1 at multiple time points. Results: 57 pt screened for VT-464 treatment, underwent HM. Nonsustained ventricular tachycardia (NSVT) was seen in 6 pts (11%) prior to VT-464, providing a background estimate in this population. 37 pts were treated with VT-464 and had > 1 post-screen HM; 4 pts (11%; all with cardiac disorders) had post-treatment NSVT (all < 5 beats); no episodes of sustained VT were seen. 28 pts had ECG data extracted from HMs that coincided with peak plasma levels of VT-464. There was no QTcF or QRS prolongation; increases in the HR (mean 13.1-19.5 BPM but with a non-significant VT-464 concentration/HR relationship) and small PR increases (mean 32.9 ms; partially driven by several pts) without second degree AV block were observed. Conclusions: VT -464 did not prolong QTcF or QRS intervals and the lack of a significant exposure response HR analysis suggests that the HR increases may not be drug related. The PR prolongation is unlikely to be clinical significance. HM showed a frequency of NSVT consistent with background frequency for this pt population.A detailed examination of study pts experiencing syncope or presyncope revealed these to likely be vasovagal in nature, consistent with the increased vagal tone observed in nonclinical testing. There does not appear to be a pro-arrhythmogenic potential of VT-464 based on data from both nonclinical and clinical assessments. Clinical trial information: NCT02361086.
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Bogdan, T. V., V. O. Onishchenko, O. V. Savchenko, and O. V. Slobodianyk. "The case report of myocarditis caused by COVID-19." Likarska sprava, no. 1-2 (May 25, 2021): 9–13. http://dx.doi.org/10.31640/jvd.1-2.2021(2).
Повний текст джерелаАнотація:
Introduction. Myocarditis is known to occur in 5–25 % of COVID-19 cases and is associated with increased mortality. According to studies, even a mild course of COVID-19 is associated with a high risk of cardiovascular disease. Possible mechanisms of myocarditis are a combination of direct viral damage to the myocardium and the human immune response to the affected myocardium. Along with acute manifestations, as fulminant myocarditis, COVID-19 may also be associated with an increased risk of long-term cardiovascular complications. Case report and discussion. The article presents a case of myocarditis that developed five weeks after active coronovirus infection in patient I., 47 years old, Ukraine, Kyiv. She described such symptoms as palpitations, shortness of breath, fever, general malaise. According to magnetic resonance imaging (MRI) of the heart: signs of focal myocarditis; according to laboratory tests, an increase in the level of acute phase indicators; according to Holter monitoring of the electrocardiogram (HM ECG) – AV blockade of the II degree (Mobitz II). The patient was prescribed : eplerinone, bisoprolol fumorate, rivaroxaban, trimetazidine. After four months of treatment, the condition of the patient gradually improved. Positive dynamics was revealed according to HM ECG and MRI of the heart. Thus, the patient was diagnosed with long-term consequences of coronavirus infection – focal myocarditis. Conclusions. Coronavirus infection causes myocardial damage with the development of myocarditis. Myocarditis can develop both in the acute period of the disease and in the long term. Scientists and physicians should pay attention to the possible consequences of COVID-19 from the first contact with the patient, and conduct long-term follow-up of patients in the long term.
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Stronа, V. I., Y. G. Gorb, and I. R. Komir. "THE VARIABILITY OF HEART RHYTHM IN PATIENTS WITH STABLE ISCHEMIC HEART DISEASE AND DIABETES MELLITUS TYPE 2." Актуальні проблеми сучасної медицини: Вісник Української медичної стоматологічної академії 18, no. 4 (December 20, 2018): 59–64. http://dx.doi.org/10.31718/2077-1096.18.4.59.
Повний текст джерелаАнотація:
The purpose of this study is to evaluate the time and spectral parameters of heart rate variability (HRV) in patients with stable type of coronary heart disease and type 2 diabetes mellitus by findings obtained by daily ECG Holter monitoring. Material and methods. The study involved 61 individuals aged 42-64 years (mean age 46.4±4.6 years) with IHD, stable exertional angina pectoris of II-III functional classes, of them 34 individuals (I group) were diagnosed to have diabetes mellitus 2 types, and 27 individuals (II group) were found to have no disorders of carbohydrate metabolism. The control group consisted of 15 individuals with essential hypertension of stage II without IHD and diabetes mellitus. All patients underwent 24-hour Holter electrocardiogram monitoring (HM ECG) with subsequent analysis of HRV parameters and evaluation of heart rhythm disturbances. Results and discussion. It was found that in both groups of IHD patients regardless the presence of diabetes, there was a decrease in the circadian index in comparison with patients with essential hypertension that probably indicates a vegetative "denervation" of the heart, the development of rigidity of the circadian circadian heart rate profile in IHD patients. With an increase in the level of glycosylated hemoglobin in the patients of I group, the temporal indices of the variability of the heart rhythm and the circadian index declined. The number of supraventricular and ventricular extrasystoles per day was statistically significantly higher in patients of I group (p <0.001, p <0.002, respectively) compared with the patients with IHD without diabetes. In the patients with coronary artery disease and diabetes, HM ECG data showed a decrease in HRV timing. This category of patients was found to have a general decrease in HRV: a SDNN decline, changes in spectral characteristics (a decrease in the high-frequency component of the spectrum (HF), an increase in the LF/HF ratio) with a shift of balance toward the sympathetic (low-frequency) component. Conclusions. Patients with stable form of ischemic heart disease and diabetes mellitus type 2 have a decrease in both temporal and spectral HRV indices that indicates a decrease in the total activity of neurohumoral effects on the heart rhythm. These changes are associated with an increase in the ectopic activity of the myocardium.
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Skuratova, N. A., A. V. Mikityuk, and V. V. Fedorova. "The Clinical and Functional Description of the Cardiovascular System in Children with Diseases of the Circulatory System." Health and Ecology Issues, no. 2 (June 28, 2019): 48–52. http://dx.doi.org/10.51523/2708-6011.2019-16-2-9.
Повний текст джерелаАнотація:
Objective: to give the clinical and functional characteristics of the cardiovascular system in children with diseases of the circulatory system. Material and мethods. The study involved 188 children aged 8-16 with different cardiovascular diseases (CVD) examined at the Cardiology Ward of Gomel Regional Children`s Hospital. Depending on the profile of their diseases, the children were divided into five main groups: group 1 - children with minor anomalies of heart development, group 2 - children with congenital heart diseases, group 3 - children with rhythm disorders, group 4 - children with autonomic dysfunction, group 5 - children with arterial hypertension. Along with the clinical examination the children were performed an electrocardiogram (ECG) and underwent Holter monitoring (HM). Results. The polymorphism of complaints was typical of the children of all the groups, according to the ECG data, conduction disturbances were the most common in the children of the first and second groups, and excitability disorders were typical of the children of the third group. Normal ECG was most often recorded in the children of the fourth and fifth groups. By the НM data arrhythmia (II Lown class and higher) was most frequently detected in the children of the first and third groups, arrhythmia of V class prevailed in the second group of the children. Conclusion. The cardiologic examination found that the children with CVD had various complaints and different arrhythmia classes, while the ECG of the majority of the children with autonomic dysfunction and hypertension detected mild arrhythmias, which is indicative of prognostically favorable disease outcomes. Clinically significant arrhythmias were revealed most frequently in the children with minor anomalies of heart development, cardiac rhythm disorders and congenital heart diseases.
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Mjahad, Azeddine, Alfredo Rosado-Muñoz, Juan Guerrero-Martínez, Manuel Bataller-Mompeán, Jose Francés-Villora, and Malay Dutta. "Detection of Ventricular Fibrillation Using the Image from Time-Frequency Representation and Combined Classifiers without Feature Extraction." Applied Sciences 8, no. 11 (October 25, 2018): 2057. http://dx.doi.org/10.3390/app8112057.
Повний текст джерелаАнотація:
Due the fact that the required therapy to treat Ventricular Fibrillation (V F) is aggressive (electric shock), the lack of a proper detection and recovering therapy could cause serious injuries to the patient or trigger a ventricular fibrillation, or even death. This work describes the development of an automatic diagnostic system for the detection of the occurrence of V F in real time by means of the time-frequency representation (T F R) image of the ECG. The main novelties are the use of the T F R image as input for a classification process, as well as the use of combined classifiers. The feature extraction stage is eliminated and, together with the use of specialized binary classifiers, this method improves the results of the classification. To verify the validity of the method, four different classifiers in different combinations are used: Regression Logistic with L2 Regularization (L 2 R L R), adaptive neural network (A N N C), Bagging (B A G G), and K-nearest neighbor (K N N). The Hierarchical Method (HM) and Voting Majority Method (VMM) combinations are used. ECG signals used for evaluation were obtained from the standard MIT-BIH and AHA databases. When the classifiers were combined, it was observed that the combination of B A G G , K N N , and A N N C using the Hierarchical Method (HM) gave the best results, with a sensitivity of 95.58 ± 0.41%, a 99.31 ± 0.08% specificity, a 98.6 ± 0.04% of overall accuracy, and a precision of 98.25 ± 0.29% for V F . Whereas a sensitivity of 94.02 ± 0.58%, a specificity of 99.31 ± 0.08%, an overall accuracy of 99.14 ± 0.43%, and a precision of 98.59 ± 0.09% was obtained for V T with a run time between 0.07 s and 0.12 s. Results show that the use of T F R image data to feed the combined classifiers yields a reduction in execution time with performance values above to those obtained by individual classifiers. This is of special utility for V F detection in real time.
Дисертації з теми "HM-ECG"
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Варналій, Артем Андрійович. "Автоматичний монітор функціонального стану серця". Master's thesis, КПІ ім. Ігоря Сікорського, 2020. https://ela.kpi.ua/handle/123456789/38609.
Повний текст джерелаАнотація:
В представленій магістерській дисертації проведені аналіз холтерівських
моніторів та розроблена система підвищеної ємності для нього.
Робота включає в себе 4 розділи та викладена 74 сторінок, містить 28 рисунків
, 26 таблиць, та додаткові матеріали, які розміщені у розділі додатки
Перший розділ присвячений аналізу літературних джерел що до холтерівських
моніторів, методикам моніторування , також розглянуто ринок холтерівських
моніторів та впливу тривалості виміру на інформативність
Другий розділ повністю присвячений проектуванню та виготовленню системи
підвищеної ємності, де була спроектована 3д модель приладу ,підібрані необхідні
компоненти та створено сам прилад.
У третьому розділі було проведено теоретичні розрахунки та аналіз їх з
вихідними даними створеної системи.
Четвертий розділ являє собою розробку стартап-проекту, для впровадження
системи для продажу.In the presented master's dissertation the analysis of Holter monitors is carried out and the system of the increased capacity for it is developed. The work includes 4 sections and 74 pages, contains 25 figures, 25 tables, and additional materials, which are placed in the section of the appendix The first section is devoted to the analysis of literature sources on Holter monitors, monitoring methods, the market of Holter monitors and the impact of measurement duration on informativeness are also considered. The second section is entirely devoted to the design and manufacture of high-capacity system, where a 3D model of the device was designed, the necessary components were selected and the device itself was created. In the third section, theoretical calculations and their analysis with the initial data of the created system were performed. The fourth section is the development of a startup project to implement a system for sale.