Дисертації з теми "HLA region"
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Sargent, Carole A. "Molecular mapping of the HLA Class III region." Thesis, University of Oxford, 1988. https://ora.ox.ac.uk/objects/uuid:b208c37f-e2d2-4ad1-a90f-524bff86c17a.
Повний текст джерелаCoriton, Olivier. "Analyse structurale de la region centromerique au locus hla-a." Rennes 1, 2000. http://www.theses.fr/2000REN10013.
Повний текст джерелаGIFFON, THIERRY. "Etude d'un nouveau gene de la region hla de classe i." Rennes 1, 1996. http://www.theses.fr/1996REN10047.
Повний текст джерелаCARN, GWENAELLE. "Analyse d'une famille multigenique de la region hla de classe i." Rennes 1, 1997. http://www.theses.fr/1997REN10084.
Повний текст джерелаAuger, Isabelle. "Isolement et caracterisation de ligands specifiques de la troisieme region hypervariable de hla-drb1#*0401 (hla-dr4 dw4). Implications pour l'association polyarthrite rhumatoide et hla-dr4." Aix-Marseille 2, 1997. http://www.theses.fr/1997AIX22032.
Повний текст джерелаALIZADEH-KASHANI, MEHDI. "Caracterisation et etude de l'expression des nouveaux genes de la region hla." Rennes 1, 1992. http://www.theses.fr/1992REN10022.
Повний текст джерелаANDRIEUX, NANCY. "Etude structurale et fonctionnelle de la partie telomerique de la region hla." Rennes 1, 1999. http://www.theses.fr/1999REN10082.
Повний текст джерелаBOURIC, PASCALE. "Etude d'une nouvelle famille multigenique de la region hla de la classe i." Rennes 1, 1997. http://www.theses.fr/1997REN10136.
Повний текст джерелаCazaubiel, Marie. "Hla de classe ii et diabete gestationnel : resultats d'une etude realisee dans la region nord-pas-de-calais." Lille 2, 1994. http://www.theses.fr/1994LIL2M170.
Повний текст джерелаCosta, Cintia Bezerra Almeida. "Polimorfismo do HLA-G na coinfecção HIV/HCV." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/22/22132/tde-21052014-181750/.
Повний текст джерелаThe general objective of the research was to associate the polymorphism of the gene HLA-G (region 3\' NT) with the co-infection HIV/HCV and with the groups (HIV, HCV and healthy control). It is a cross-sectional, comparative, descriptive study. 560 individuals participated of the study, being 156 healthy control individuals, 102 co- infected HIV/HCV, 186 infected by HIV and 116 by HCV. For identifying the polymorphisms, the genomic DNA was extracted from the total blood and the genotyping was made by PCR and visualized in gel of polyacrylamide at 7%, in which the polymorphism of 14pb was identified, and by sequencing the other seven SNPs. The social demographic results point that the most of the sample was composed by male adult individuals. Regarding the color of the skin, in the comparison between the groups HCV and HIV/HCV, a bigger number of co-infected with black skin and brown-skinned was observed than in the mono infected (P=0,0001). Regarding to the category of exposition for acquisition of the HIV, in the comparison between the groups HIV and HIV/HCV, a significant difference was observed in the transmission through heterosexual exposition, being its frequency bigger in the group HIV (P=0,0000). In the case of the comparison between the groups HCV and HIV/HCV, the difference in the heterosexual transmission was also observed, being its frequency significantly higher in the group HIV/HCV (P=0,0001). About the finding related to the genotype of the HCV, in the comparison between the groups HCV and HIV/HCV, the genotype 1a presented higher frequency in the co- infected (P=0,0001). Regarding to the viral load of the HIV, in the comparison between the groups HIV and HIV/HCV, the group of the mono infection presented bigger viral load that the group of the co-infection (P=0,0350). Regarding to the level of hepatic fibrosis, in the comparison between the groups HCV and HIV/HCV, the group of co-infection has a lighter fibrosis that the group of the mono infection (P=0,0009). Regarding to the genetic polymorphisms of the region 3\' NT of the HLA-G, it was found that the genotype of heterozygosis Del/Ins of 14 pb, presented significant difference in the individuals co-infected by the HIV/HCV (P=0,0216) when compared with the control group. About the SNP +3003, the comparison of the groups HCV and healthy control, it was showed that the allele +3003T presented a significant higher frequency in the group HCV (P=0,0147); the genotype +3003C/T presented a higher frequency in the control group (P=0,0095); the genotype +3003T/T was bigger in the group HCV (P=0,0095). The comparison between the groups HIV and HCV showed that the frequency of the allele +3003C was bigger in the group HIV (P=0,0463); and the genotype +3003T/T presented a bigger frequency in the group (P=0,0494). The frequency of the genotype +3187A/A was bigger in the group HIV/HCV in comparison to the HIV (P=0,0193); and of the +3187A/G was bigger in the group HIV (P=0,0187). The genotype +3196C/G presented frequency significantly bigger in the group HIV than in the healthy control (P=0,0213). The UTR-10, in comparison between the groups HIV and control, showed bigger frequency in the group HIV (P=0,0044); when compared the groups HIV/HCV and HIV, frequency was bigger in the group HIV (P=0,0300) and in the comparison between the groups HIV and HCV, its frequency was also bigger in the group (P=0,0140). The UTR-4, in the comparison of the groups HCV and healthy control, revealed a bigger frequency in the control group (P=0,0147). The UTR-9, in comparison of the groups HIV/HCV and HIV, showed bigger frequency in the group HIV/HCV (P=0,0460). Regarding to the clinical data, the presence of the allele T in the position +3035, was significantly associated to bigger viral load of the HCV, above 400.000 copies /mL (P=0,0244). About the types of genotypes of the HCV, the presence of the allele +3027C was associated with the subtype 1a of the HCV (P=0,0109). Additionally, the presence of the genotype C/C in the position +3027 was also significantly associated with the subtype 1a of the HCV (P=0,0015). Still, the allele A of the SNP +3187 was significantly associated with the other genotypes of the HCV, excluding the 1a (P=0,0369). Although the function of the gene HLA-G, is not totally clarified, studies have been developed for better elucidate its function in the physiological contexts, like gestation, and pathological, such as tumours, transplants, infectious and inflammatory diseases. These studies aim to extend the knowledge about the immunological system and contribute for the development of new diagnostic and therapeutic strategies. The results of this study contribute for enhancement of the knowledge about the polymorphisms of the region 3\' NT of the gene HLA-G, in the co-infection HIV/HCV. As well as, in the improvement of the assistance of nursing that must seek reducing the morbid mortality by the pathology referred. However, there is still a long path to be followed in the comprehension of the immunogenic factors involved in the co-infection by the HIV/HCV
CHAUVEL, BRUNO. "Genetique moleculaire de l'hemochromatose : analyse d'un nouveau gene de la region hla de class i." Rennes 1, 1996. http://www.theses.fr/1996REN10057.
Повний текст джерелаPichon, Laurent. "Cartographie physique de la region hla de classe i etude de nouveaux genes de structure." Rennes 1, 1996. http://www.theses.fr/1996REN10042.
Повний текст джерелаLEPOURCELET, MAINA. "Etablissement d'un ensemble continu de cosmides dans la region hla-a/hla-f et identification d'un groupe de genes apres sequencage d'un cosmide de 37 kb." Rennes 1, 1996. http://www.theses.fr/1996REN10065.
Повний текст джерелаMARTELL, MARIA. "Le diabete juvenile, une maladie multifactorielle : analyse par la genetique moleculaire des facteurs de la region hla." Paris 6, 1990. http://www.theses.fr/1990PA066227.
Повний текст джерелаEL, KAHLOUN ABDELGHAFOUR. "Cartographie physique de la region hla classe i par electrophorese en champ pulse. Application a la genetique moleculaire de l'hemochromatose." Rennes 1, 1991. http://www.theses.fr/1991REN10115.
Повний текст джерелаLintner, Katherine E. "The Roles of Complement C4A and C4B Genetic Diversity and HLA DRB1 Variants on Disease Associations with Juvenile Dermatomyositis and Systemic Lupus Erythematosus." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1460986052.
Повний текст джерелаGu, Yunfeng. "Data Distribution Management In Large-scale Distributed Environments." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/20691.
Повний текст джерелаHABITA, CELLIA KARIMA. "Identification de regions non-hla liees au diabete insulino-dependant." Paris 7, 1998. http://www.theses.fr/1998PA077074.
Повний текст джерелаSukiennicki, Teresa Lyn. "Regulation of expression of the HLA class II gene, DQB1 /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/8358.
Повний текст джерелаSilva, Daniel Melchiades da. "Rejeição aguda em enxertos renais com disfunção inicial : a influência do regime imunossupressor e da compatibilidade HLA." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2007. http://hdl.handle.net/10183/8895.
Повний текст джерелаCastle, Marianne Q. L. "Immunogenetics of multiple sclerosis : an investigation of the alleles of the HLD-A region /." View thesis, 1995. http://library.uws.edu.au/adt-NUWS/public/adt-NUWS20030825.155933/index.html.
Повний текст джерелаIngebrigtsen, Sofia. "Sluta flytta runt saker hela tiden! : En vetenskaplig essä om utmaningar i förskolans innemiljö." Thesis, Södertörns högskola, Lärarutbildningen, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-34344.
Повний текст джерелаMin vetenskapliga essä utgår från en serie händelser där jag anser att både jag och min kollega handlade oprofessionellt och inte hade barnens bästa för ögonen. Händelserna utspelade sig inom min yrkesverksamma tid som outbildad barnskötare. Dilemmat handlade om de krockar som uppstod mellan mig och min kollega, när jag kom som ny men erfaren pedagog till hennes avdelning. En avdelning med, enligt mig, undermålig pedagogisk inomhusmiljö. Jag kom med nya idéer om hur den skulle ändras, men diskuterade inte det med min kollega eller barnen innan jag ändrade i den. Detta gjorde att vi hamnade i konflikt med varandra, både på grund av mitt förhastade handlande men även på grund av hennes otydliga ledarskap. Syftet med den vetenskapliga essän har varit att reflektera över vikten av att vi pedagoger kommunicerar med varandra och vilka konsekvenserna blir när vi inte gör det. Jag undersökte hur maktfördelningen mellan oss pedagoger kan te sig och vikten av att ha en god pedagogisk inomhusmiljö på förskolan. De frågeställningar jag utgått från är: Vad kännetecknar en bra pedagogisk miljö? Hur får man till bra samarbeten och samarbetsformer i ett nytt arbetslag? Hur påverkar maktfördelningen mellan pedagogerna det pedagogiska arbetet i förskolan? Jag har använt metoden reflektion för att kunna undersöka mitt dilemma. Jag valde att använda mig av Reggio Emilia pedagogiken, för att reflektera över barnens del i den miljön de vistas i varje dag. Jag har reflekterat kring kunskapsperspektivet med utgångspunkt i Aristoteles bok Den Nikomachiska etiken, där jag fokuserat på de tre kunskapsformerna; episteme, techne och fronesis. Sist men inte minst har jag reflekterat utifrån ett maktperspektiv med utgångspunkt i några av Foucaults tankar om makt. Det har framkommit i mina individuella reflektioner samt i diskussioner med mina kurskamrater och arbetskollegor att detta är ett vanligt dilemma och att det ofta förekommer konflikter när starka viljor möts och ska sammansvetsas till ett fungerande arbetslag.
Akyuz, Gozde. "Teacher And Classroom Characteristics: Their Relationship With Mathematics Achievement In Turkey, European Union Countries And Candidate Countries." Phd thesis, METU, 2006. http://etd.lib.metu.edu.tr/upload/12607361/index.pdf.
Повний текст джерелаmathematics achievement across Turkey,European Union countries and the other candidate countries by analysing the data collected from student and teacher background questionnaire and mathematics achievement test in the Third International Mathematics and Science Study (TIMSS-R). Mathematics teacher characteristics were divided into three groups as teacher&rsquo
s background variables, teacher&rsquo
s instructional practices and class characteristics. Except Cyprus, in all the other countries, there was sufficient amount of between-class variance to build explanatory models. After home educational resources (HER) of students was taken as a control variable, explanatory models were built by using Hierarchical Linear Modeling (HLM). The amount of variance explained by the full model ranged from 26 % in Romania to 74 % in Netherlands. There were substantial differences among the countries, especially in the teacher&rsquo
s instructional practices. It was found that mean of HER had high effect on student mathematics achievement in all the countries except Romania. It is recommended that the factors that were found to have significant effects on student learning should be explored in experimental settings.
Lundell, Linnéa, and Åsa Fransson. "”De vill att vi läser för dem mest hela tiden” : En kvalitativ studie om hur förskollärarna beskriver förskolans läsmiljö." Thesis, Högskolan för lärande och kommunikation, Jönköping University, Förskolepedagogisk-didaktisk forskning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-50111.
Повний текст джерелаAl, Qasem Hala [Verfasser], Uwe [Gutachter] Liebert, and Brigitte [Gutachter] König. "Molecular Characterization of Carbapenemases and Quinolone Resistance Determining Region Enzymes-Producing Isolates in an Outbreak at the University Hospital of Leipzig / Hala Al Qasem ; Gutachter: Uwe Liebert, Brigitte König." Leipzig : Universitätsbibliothek Leipzig, 2014. http://d-nb.info/1238789900/34.
Повний текст джерелаAlameddine, Josefine. ""Att 'simma' i hela sin personlighet" : En genuskritisk diskursanalys om subjektivitet och kön, av ett urval texter om Reggio Emilia-filosofin." Thesis, Stockholms universitet, Institutionen för pedagogik och didaktik, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-62150.
Повний текст джерелаBarlas, Frances M. "Investigating The Dual Mortgage Market: The Distribution Of Subprime Lending By Race And Its Consequences For Minority Communities." Diss., Temple University Libraries, 2009. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/55002.
Повний текст джерелаPh.D.
This dissertation examines the overlap of the racial composition of a neighborhood and the existence of a dual mortgage market in which prime and subprime lenders serve different neighborhoods and borrowers. Does subprime lending represent the democratization of credit or does it serve to track people by race? This dissertation employs Home Mortgage Disclosure Act Data, U.S. Census Data and the HUD Subprime Lender List to identify subprime loans. I use Hierarchical Linear Modeling to predict the likelihood of subprime for a borrower in Philadelphia, Baltimore, San Francisco and Alameda County California. The findings demonstrate that blacks and borrowers in black neighborhoods have a higher likelihood of originating a subprime loan than whites or borrowers in white neighborhoods. Further, blacks borrowing in largely white neighborhoods have an even higher likelihood of originating a subprime loan compared to their white neighbors than do blacks borrowing in largely black neighborhoods. These findings indicate that subprime lenders not only serve different neighborhoods, but also different borrowers regardless of the neighborhood in which they are borrowing and support the existence of a dual mortgage market that is defined by race. The results from the analysis examining the consequences of subprime lending for neighborhoods indicate that after controlling for neighborhood characteristics, the positive relationship between earlier and later rates of subprime lending disappears. Also, while higher rates of subprime refinance lending were associated with a decrease in neighborhood median income in 2000, subprime lending was associated with positive changes in median house value and percent of homeowners that are black in the neighborhood, although the effects of subprime on median house value disappeared after controlling for neighborhood conditions. The study points to the continued difficulties that black borrowers and borrowers in black neighborhoods face in obtaining a fair loan. As lending practices are reformed, it is important to keep in mind the need to ensure that minority borrowers who are in the position to afford a home loan maintain the ability to get a loan, but increased care must be taken to ensure that they obtain the ability to do so on fair terms.
Temple University--Theses
Kübler, Kirsten Andrea. "Qualitative und quantitative Alterationen verschiedener Loci der HLA-Klasse-II Region beim Ovarialkarzinom /." 2005. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014644542&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Повний текст джерелаPrestel, Hideko. "Untersuchung zur Lokalisierung der Empfänglichkeits-Loci für Psoriasis in der HLA-Region auf Chromosom 6 /." 2004. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=014191877&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Повний текст джерелаOgierman, Monica Anne. "Molecular characterisation of the Haemolysin (HlyA) and the Region Downstream of hlyA in Vibrio cholerae O1." Thesis, 1998. http://hdl.handle.net/2440/19173.
Повний текст джерела166, [139] leaves : ill. ; 30 cm.
Provides insights into the structure/function relationships within the El Tor haemolysin (HlyA). Generates some constructs used to determine the three-dimensional structure of the protein and of the pore. The genetic organisation of the region flanking the hly locus suggests a pathogenicity island.
Thesis (Ph.D.)--University of Adelaide, Dept. of Microbiology and Immunology, 1998
Olufemi, Ajibola Olalekan. "Assessing the impact of Housing Development Agency (HDA) across the Gauteng City Region (GCR)." Thesis, 2017. https://hdl.handle.net/10539/24011.
Повний текст джерелаThe lack of capacity, coordination and pervasive corruption are the views commonly associated with local implementation agencies particularly when it comes to housing construction and delivery in South Africa. One of the reasons for these views could be associated with the increasing backlog of adequate housing couple with the ever-increasing number of housing need within the country. From the governmental point of view, a lot of progress regarding housing delivery have been recorded since 1994 through different delivery strategies. However, different spheres of government particularly the local level feels the need that a lot still needs to be done in order to keep up with the increasing demand and also to cater for the sustainability of these different housing projects. The need for a sustainable housing project has resulted to the establishment of The Housing Development Agency (HDA) in 2009 under a close supervision and monitoring by The National Department of Human Settlement (NDHS). HDA is expected to operate independently in addressing the shortage of housing. Its mandate was that of identifying, acquiring and developing well-located land for building and establishment of human settlements. Established at a National Level, the services they render cut across the provincial and municipal sphere of government. The Housing Development Agency (HDA) has been in charge of Housing delivery over the past 6 years with different development within the Gauteng City Region (GCR) i.e. Johannesburg, Tshwane and Ekurhuleni but despite this, most communities within Gauteng province are far from achieving an integrated and sustainable human settlement. This research seeks to understand if there are any challenges vis-à-vis coordination between HDA and local implementation agencies in Gauteng province while considering different implementation approaches, strategies, chosen catalytic and interventions in achieving spatial transformation amongst these three selected municipalities. The research utilized the various reports from present, past and future development strategies of HDA and in comparison, with the three local implementation agencies strategies, diverse qualitative information was collected and analysed in relation to the location of the identified human settlement projects within the GCR areas. Furthermore, Interview guideline questions were structured to guide various interview sessions with senior HDA administrative officials. Conversation analysis method was further used to filter the interview sessions while making sure the confidentiality of my participants is not jeopardized. Finally, finding from this study highlights that municipalities are striving to achieve a sustainable and socially integrated housing development particularly in Gauteng but the stereotype cross cutting issues like access to information, gender, race, disability and income are serious challenges HDA or any private agency needs to deal with in order for it to achieve any given mandate.
MT 2018
Klicperová, Barbora. "Regionální rozdíly v naději dožití ve zdraví v Česku." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-382975.
Повний текст джерела