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Статті в журналах з теми "High Q² sensitivity"

Автор: Grafiati

Опубліковано: 14 грудня 2024

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1

Zhang, Yuguang, Shoubao Han, Senlin Zhang, Penghao Liu, and Yaocheng Shi. "High-Q and High-Sensitivity Photonic Crystal Cavity Sensor." IEEE Photonics Journal 7, no. 5 (October 2015): 1–6. http://dx.doi.org/10.1109/jphot.2015.2469131.

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2

Helm, P. J. S., M. Dagenais, M. A. Krainak, and R. Leavitt. "High-sensitivity semiconductor optically preamplified Q-PPM receiver." IEEE Photonics Technology Letters 9, no. 10 (October 1997): 1394–96. http://dx.doi.org/10.1109/68.623274.

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3

Gaber, Noha, Yasser Sabry, Mazen Erfan, Frédéric Marty, and Tarik Bourouina. "High-Q Fabry–Pérot Micro-Cavities for High-Sensitivity Volume Refractometry." Micromachines 9, no. 2 (January 31, 2018): 54. http://dx.doi.org/10.3390/mi9020054.

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4

Conradi, Mark S. "Marginal oscillators: High sensitivity, simple detectors of Q changes." Journal of the Acoustical Society of America 95, no. 5 (May 1994): 2811. http://dx.doi.org/10.1121/1.409741.

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5

Kim, Sejeong, Hwi-Min Kim, and Yong-Hee Lee. "Single nanobeam optical sensor with a high Q-factor and high sensitivity." Optics Letters 40, no. 22 (November 10, 2015): 5351. http://dx.doi.org/10.1364/ol.40.005351.

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6

Lalauze, R., C. Pijolat, S. Vincent, and L. Bruno. "High-sensitivity materials for gas detection." Sensors and Actuators B: Chemical 8, no. 3 (June 1992): 237–43. http://dx.doi.org/10.1016/0925-4005(92)85024-q.

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7

Hu, Senyong, Yunhao Cao, Shengxiao Jin, and Wengang Wu. "Design of a high-sensitivity and high-Q microwave sensor based on H-fractal metasurface structure." Advances in Engineering Technology Research 1, no. 3 (February 2, 2023): 850. http://dx.doi.org/10.56028/aetr.3.1.850.

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Анотація:

This paper proposes a metasurface based on H-fractal unit structure, which exhibits three transmission resonance peaks. The simulation results show that these peaks are very sensitive to samples with different refractive indexes. The biggest frequency shift of these resonant peaks is about 2.6 GHz when the refractive index of samples changes by 1 and the quality factor(Q) values of the second and the third peak are up to 191.55 and 179.40 respectively, which has great application potential in the field of microwave sensing because its high-sensitivity and high-Q.

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8

Khusnutdinov, R. R., G. V. Mozzhukhin, N. R. Khusnutdinova, and B. M. Salakhutdinov. "High-Q litz wire NQR sensor for medical applications." Power engineering: research, equipment, technology 25, no. 3 (August 21, 2023): 3–11. http://dx.doi.org/10.30724/1998-9903-2023-25-3-3-11.

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RELEVANCE. The design and development of radio frequency (RF) coil sensors is an important engineering and, at the same time, fundamental task for those radio spectroscopic instruments that require an increase in sensitivity, measured as a signal-to-noise ratio (SNR). Radio spectroscopy of nuclear quadrupole resonance (NQR), especially in nitrogen compounds, in which the resonant frequency is very low and ranges from a few megahertz or lower to hundreds of kilohertz, requires the use of special solutions to increase the sensitivity. PURPOSE. Theoretical substantiation and search for a technical solution that allows achieving high sensitivity on standard equipment through the use of a high-quality sensor. METHODS. Methods for optimizing the design of sensors for NQR/NMR spectrometers are considered. The design of the sensor for the NQR spectrometer, which contains an inductance coil wound with a Litz wire, has been calculated and designed. RESULTS. A high-quality coil for the spectrometer sensor was made, which gives an increase in the quality factor by about 1.5 times. The use of a spectrometer with this coil made it possible to confidently record weak noisy signals of paracetamol at a low duty cycle. The sensitivity of the sensor made it possible to distinguish preparations from different manufacturers by their spectral characteristics. CONCLUSIONS. A solenoid sensor has been developed, modeled and manufactured, which has a high quality factor and allows recording quadrupole resonance signals of drugs (paracetamol) by a non-destructive method directly through the package. The possibility of using such a sensor for quality control of medicines, detection of falsified and counterfeit medicines is shown.

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9

Clevenson, Hannah, Pierre Desjardins, Xuetao Gan, and Dirk Englund. "High sensitivity gas sensor based on high-Q suspended polymer photonic crystal nanocavity." Applied Physics Letters 104, no. 24 (June 16, 2014): 241108. http://dx.doi.org/10.1063/1.4879735.

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10

Ling, Tao, Sung-Liang Chen, and L. Jay Guo. "High-sensitivity and wide-directivity ultrasound detection using high Q polymer microring resonators." Applied Physics Letters 98, no. 20 (May 16, 2011): 204103. http://dx.doi.org/10.1063/1.3589971.

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11

Li, Tingyu, Dingshan Gao, Daming Zhang, and Eric Cassan. "High- $Q$ and High-Sensitivity One-Dimensional Photonic Crystal Slot Nanobeam Cavity Sensors." IEEE Photonics Technology Letters 28, no. 6 (March 15, 2016): 689–92. http://dx.doi.org/10.1109/lpt.2015.2504722.

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12

Li, Bei-Bei, Qing-Yan Wang, Yun-Feng Xiao, Xue-Feng Jiang, Yan Li, Lixin Xiao, and Qihuang Gong. "On chip, high-sensitivity thermal sensor based on high-Q polydimethylsiloxane-coated microresonator." Applied Physics Letters 96, no. 25 (June 21, 2010): 251109. http://dx.doi.org/10.1063/1.3457444.

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13

Yang, Daquan, Huiping Tian, Yuefeng Ji, and Qimin Quan. "Design of simultaneous high-Q and high-sensitivity photonic crystal refractive index sensors." Journal of the Optical Society of America B 30, no. 8 (July 3, 2013): 2027. http://dx.doi.org/10.1364/josab.30.002027.

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14

Bonino, Vittorio, and Angelo Angelini. "High-Q Fano resonances in diamond nanopillars." Optical Materials Express 13, no. 4 (March 24, 2023): 1110. http://dx.doi.org/10.1364/ome.484614.

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We report on the optical behaviour of a nanostructured diamond surface on a glass substrate. The numerical model reveals that a simple geometrical pattern sustains Fano-like resonances with a Q-factor as high as 3.5 · 105 that can be excited by plane waves impinging normally on the surface. We show that the geometrical parameters of the nanopillars affect both the resonant frequency and the line shape. The nanostructured surface can be straightforwardly used as a refractive index sensor with high sensitivity and linearity. Our findings show that diamond-based meta-surfaces are a valuable nanophotonic platform to control light propagation at the nanoscale, enabling large field enhancement within the nanoresonators that can foster both linear and nonlinear effects.

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15

Qiuting Huang and W. Sansen. "A low-sensitivity, low-capacitance ratio realization of high-Q biquads." IEEE Transactions on Circuits and Systems 33, no. 10 (October 1986): 1039–42. http://dx.doi.org/10.1109/tcs.1986.1085847.

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16

Yurianto, Yurianto, Pratikto Pratikto, Rudy Soenoko, and Wahyono Suprapto. "Welding method for high crack sensitivity of Q&T steel." Eastern-European Journal of Enterprise Technologies 4, no. 12 (100) (August 28, 2019): 43–51. http://dx.doi.org/10.15587/1729-4061.2019.176959.

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17

Kobayashi, Naritaka, Yan Jun Li, Yoshitaka Naitoh, Masami Kageshima, and Yasuhiro Sugawara. "High force sensitivity in Q-controlled phase-modulation atomic force microscopy." Applied Physics Letters 97, no. 1 (July 5, 2010): 011906. http://dx.doi.org/10.1063/1.3457431.

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18

Al-Hmoud, M. "High-Sensitivity and Wide Detection-Range Refractive-Index Sensor Based on Amplitude Change in Slotted Photonic Crystal Nanobeam Cavity." Journal of Nanoelectronics and Optoelectronics 18, no. 6 (June 1, 2023): 673–79. http://dx.doi.org/10.1166/jno.2023.3435.

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High Q-factor is essential for the realization of high sensitivity photonic crystal-based sensors. The Q-factor is usually optimized for a specific refractive-index (RI) value of the ambient background. However, a small change in the RI reduces the Q value, and therefore limits the performance of the sensor to a narrow RI range. Here, we report a high-sensitivity RI sensor with a wide detection-range based on amplitude change of the fundamental mode in slotted photonic crystal nanobeam cavity. Both wavelength and amplitude sensitivity of 333 nm/RIU and 188/RIU are realized in the RI range from 1.3 to 1.6, respectively. To the best of our knowledge, this represents the widest sensing range ever reported in photonic crystal cavities. Owing to the wide sensing range and the insignificance of the Q value, this approach would find applications in various research areas in integrated lab-on-chip systems for optofluidic- and bio-sensing applications.

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19

Rao, Shilpakala Sainath, Ketha V. K. Mohan, and Chintamani D. Atreya. "High Sensitivity Detection of Bacillus Cereus in Plasma Samples." Blood 112, no. 11 (November 16, 2008): 1990. http://dx.doi.org/10.1182/blood.v112.11.1990.1990.

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Abstract Microbial contamination of blood and blood products remains a major concern in transfusion medicine. Detection of bacterial contamination has been traditionally carried out by inoculating the contaminated blood/blood products into a liquid or solid nutrient medium followed by 18–24 h incubation period to observe any bacterial colony formation (growth). Although this technique is highly sensitive and specific, the test requires at least 24 hours for accurate diagnosis, which is a limitation Nucleic acid-based and antigen-based assays that have been recently in use also have limitations either with regard to time, sensitivity or specificity. In the present study we utilized Bacillus cereus and bacteriolysin (PlyG) derived from its g-phage virus as a model system for high sensitivity detection of this B. cereus in plasma. Six overlapping synthetic peptides in the bacterial binding C-terminal region of PlyG were tested in the study. The length of the synthetic peptides ranged from 20 to 10-mer and were biotinylated for subsequent detection. Peptide binding to bacteria was detected using either Streptavidin-conjugated horse radish peroxidase (HRP) on a nitrocellulose membrane or by using streptavidin-conjugated fluorescent Q-dots (liquid nano crystals) and analyzing under a fluorescence microscope. Various dilutions of log-phase cultures of B. cereus were spiked into plasma samples and incubated with the peptides for 1 hour followed by detection using either the streptavidin-HRP or streptavidin-Q-dots. Results revealed that two out of six peptides bound strongly to Bacillus in both the assays, while the rest of the peptides were either non-binders or weakly-binding. The membrane-based assay demonstrated an assay sensitivity of 102 colony forming units (CFU)/ml whereas the Q dots-based fluorescence assay was able to detect even a single bacterium. Overall, our findings suggest that both these assays are rapid and sensitive and results could be achieved within 2–3 hours. Quantitation of the fluorescent signal by fluorometry in a 96-well plate format is in progress. The findings and conclusions in this abstract have not been formally disseminated by the Food and Drug Administration and should not be construed to represent any Agency determination or policy.

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20

Wu, Nishan, and Li Xia. "High-Q and high-sensitivity multi-hole slot microring resonator and its sensing performance." Physica Scripta 94, no. 11 (August 23, 2019): 115512. http://dx.doi.org/10.1088/1402-4896/ab3266.

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21

Chakravarty, Swapnajit, Yi Zou, Wei-Cheng Lai, and Ray T. Chen. "Slow light engineering for high Q high sensitivity photonic crystal microcavity biosensors in silicon." Biosensors and Bioelectronics 38, no. 1 (October 2012): 170–76. http://dx.doi.org/10.1016/j.bios.2012.05.016.

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22

Wang, Wudeng, Li Zheng, Li Xiong, Jianguang Qi, and Baoying Li. "High Q-factor multiple Fano resonances for high-sensitivity sensing in all-dielectric metamaterials." OSA Continuum 2, no. 10 (September 23, 2019): 2818. http://dx.doi.org/10.1364/osac.2.002818.

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23

Al-Hmoud, Mohannad, and Rasha Alyahyan. "High sensitivity and low detection limit sensor based on a slotted nanobeam cavity." Photonics Letters of Poland 14, no. 3 (September 30, 2022): 59. http://dx.doi.org/10.4302/plp.v14i3.1161.

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In this work, the three-dimensional finite-difference time-domain (3D-FDTD) method is used to design and analyze a refractive index sensor based on a slotted photonic crystal nanobeam cavity. These type of cavities support a high quality-factor and a small volume, and therefore is attractive for optical sensing. We demonstrate that when immersing our proposed sensor in water it can possess a high-quality factor of 2.0×10^6, high sensitivity of 325 nm/RIU, and a detection limit of 2.4×10^(-7) RIU. We believe that our proposed sensor is a promising candidate for potential applications sensing like in optofluidic- and bio-sensing. Full Text: PDF ReferencesE. Chow, A. Grot, L. Mirkarimi, M. Sigalas, G. Girolami, "Ultracompact biochemical sensor built with two-dimensional photonic crystal microcavity", OSA Trends Opt. Photonics Ser. 97 909 (2004). CrossRef S. Kim, H-M. Kim, Y-H. Lee, "Single nanobeam optical sensor with a high Q-factor and high sensitivity", Opt. Lett. 40 5351 (2015). CrossRef D-Q, Yang, B Duan, X, Liu, A-Q, Wang, X-G, Li, Y-F, Ji, "Photonic Crystal Nanobeam Cavities for Nanoscale Optical Sensing: A Review", Micromachines 11 (2020). CrossRef P.B. Deotare, M.W. McCutcheon, I.W. Frank, M. Khan, M. Lončar, "High quality factor photonic crystal nanobeam cavities", Appl. Phys. Lett. 94 121106 (2009). CrossRef P. Seidler, K. Lister, U. Drechsler, J. Hofrichter, T. Stöferle, "Slotted photonic crystal nanobeam cavity with an ultrahigh quality factor-to-mode volume ratio", Opt. Express 21 32468 (2013). CrossRef H. Choi, M. Heuck, D. Englund, "Self-Similar Nanocavity Design with Ultrasmall Mode Volume for Single-Photon Nonlinearities", Phys. Rev. Lett. 118 223605 (2017). CrossRef M. Al-Hmoud, S. Bougouffa, "Simultaneous high Q/V-ratio and optimized far-field emission pattern in diamond slot-bridge nanobeam cavity", Results Phys. 26 104314 (2021). CrossRef Q. Quan (2014). CrossRef M.A. Butt, C. Tyszkiewicz, P. Karasiński, M. Zięba, D. Hlushchenko, T. Baraniecki, A. Kaźmierczak, R. Piramidowicz, M. Guzik, A. Bachmatiuk, "Development of a low-cost silica-titania optical platform for integrated photonics applications", Opt. Express 30 23678 (2022). CrossRef D-Q. Yang, B. Duan, X. Liu, A-Q. Wang, X-G. Li, Y-F. Ji, ""Photonic Crystal Nanobeam Cavities for Nanoscale Optical Sensing: A Review", Micromachines 72, 11 (2020). CrossRef Y.N. Zhang, Y. Zhao, R.Q Lv, "A review for optical sensors based on photonic crystal cavities", Sens. Actuators A: Phys. 233 374 (2015). CrossRef P. Lalanne, S. Mias, and J.P. Hugonin, "Two physical mechanisms for boosting the quality factor to cavity volume ratio of photonic crystal microcavities", Opt. Express 12 458 (2004). CrossRef C. Sauvan, G. Lecamp, P. Lalanne, J.P Hugonin, "Modal-reflectivity enhancement by geometry tuning in Photonic Crystal microcavities", Opt. Express 13 245 (2005). CrossRef J.T. Robinson, C. Manolatou, L. Chen, M. Lipson, "Ultrasmall Mode Volumes in Dielectric Optical Microcavities", Phys. Rev. Lett. 95 143901 (2005). CrossRef S. Olyaee, M. Seifouri, R. Karami, A. Mohebzadeh-Bahabady, "Designing low power and high contrast ratio all-optical NOT logic gate for using in optical integrated circuits", Opt. Quantum Electron. 51 1 (2019). CrossRef

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24

Chen, Jiamin, Chenyang Xue, Yongqiu Zheng, Jiandong Bai, Xinyu Zhao, Liyun Wu, and Yuan Han. "Acoustic Performance Study of Fiber-Optic Acoustic Sensors Based on Fabry–Pérot Etalons with Different Q Factors." Micromachines 13, no. 1 (January 12, 2022): 118. http://dx.doi.org/10.3390/mi13010118.

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The ideal development direction of the fiber-optic acoustic sensor (FOAS) is toward broadband, a high sensitivity and a large dynamic range. In order to further promote the acoustic detection potential of the Fabry–Pérot etalon (FPE)-based FOAS, it is of great significance to study the acoustic performance of the FOAS with the quality (Q) factor of FPE as the research objective. This is because the Q factor represents the storage capability and loss characteristic of the FPE. The three FOASs with different Q factors all achieve a broadband response from 20 Hz to 70 kHz with a flatness of ±2 dB, which is consistent with the theory that the frequency response of the FOAS is not affected by the Q factor. Moreover, the sensitivity of the FOAS is proportional to the Q factor. When the Q factor is 1.04×106, the sensitivity of the FOAS is as high as 526.8 mV/Pa. Meanwhile, the minimum detectable sound pressure of 347.33 μPa/Hz1/2 is achieved. Furthermore, with a Q factor of 0.27×106, the maximum detectable sound pressure and dynamic range are 152.32 dB and 107.2 dB, respectively, which is greatly improved compared with two other FOASs. Separately, the FOASs with different Q factors exhibit an excellent acoustic performance in weak sound detection and high sound pressure detection. Therefore, different acoustic detection requirements can be met by selecting the appropriate Q factor, which further broadens the application range and detection potential of FOASs.

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25

Al-Gburi, Ahmed Jamal Abdullah, Norhanani Abd Rahman, Zahriladha Zakaria, and Muhammad Firdaus Akbar. "Realizing the High Q-Factor of a CSIW Microwave Resonator Based on an MDGS for Semisolid Material Characterization." Micromachines 14, no. 5 (April 24, 2023): 922. http://dx.doi.org/10.3390/mi14050922.

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In this work, the high-quality factor (Q-factor) and high sensitivity of a circular substrate-integrated waveguide (CSIW) are proposed for the characterization of semisolid materials. The modeled sensor was designed based on the CSIW structure with a mill-shaped defective ground structure (MDGS) to improve measurement sensitivity. The designed sensor oscillates at a single frequency of 2.45 GHz, which was simulated using an Ansys HFSS simulator. Electromagnetic simulation explains the basis of the mode resonance of all two-port resonators. Six variations of the materials under test (SUTs) were simulated and measured, including air (without an SUT), Javanese turmeric, mango ginger, black turmeric, turmeric, and distilled water (DI). A detailed sensitivity calculation was performed for the resonance band at 2.45 GHz. The SUT test mechanism was performed using a polypropylene tube (PP). The samples of dielectric material were filled into the channels of the PP tube and loaded into the center hole of the MDGS. The E-fields around the sensor affect the relationship with the SUTs, resulting in a high Q-factor value. The final sensor had a Q-factor of 700 and a sensitivity of 2.864 at 2.45 GHz. Due to the high sensitivity of the presented sensor for characterization of various semisolid penetrations, the sensor is also of interest for accurate estimation of solute concentration in liquid media. Finally, the relationship between the loss tangent, permittivity, and Q-factor at the resonant frequency were derived and investigated. These results make the presented resonator ideal for the characterization of semisolid materials.

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26

Shtirberg, Lazar, Ygal Twig, Ekaterina Dikarov, Revital Halevy, Michael Levit, and Aharon Blank. "High-sensitivity Q-band electron spin resonance imaging system with submicron resolution." Review of Scientific Instruments 82, no. 4 (April 2011): 043708. http://dx.doi.org/10.1063/1.3581226.

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27

Cuthbertson, B. D., M. E. Tobar, E. N. Ivanov, and D. G. Blair. "Sensitivity and optimization of a high-Q sapphire dielectric motion-sensing transducer." IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 45, no. 5 (September 1998): 1303–13. http://dx.doi.org/10.1109/58.726457.

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28

Kampschreur, Linda M., Jan Jelrik Oosterheert, Annemarie M. C. Koop, Marjolijn C. A. Wegdam-Blans, Corine E. Delsing, Chantal P. Bleeker-Rovers, Monique G. L. De Jager-Leclercq, et al. "Microbiological Challenges in the Diagnosis of Chronic Q Fever." Clinical and Vaccine Immunology 19, no. 5 (March 21, 2012): 787–90. http://dx.doi.org/10.1128/cvi.05724-11.

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ABSTRACTDiagnosis of chronic Q fever is difficult. PCR and culture lack sensitivity; hence, diagnosis relies mainly on serologic tests using an immunofluorescence assay (IFA). Optimal phase I IgG cutoff titers are debated but are estimated to be between 1:800 and 1:1,600. In patients with proven, probable, or possible chronic Q fever, we studied phase I IgG antibody titers at the time of positive blood PCR, at diagnosis, and at peak levels during chronic Q fever. We evaluated 200 patients, of whom 93 (46.5%) had proven, 51 (25.5%) had probable, and 56 (28.0%) had possible chronic Q fever. Sixty-five percent of proven cases had positiveCoxiella burnetiiPCR results for blood, which was associated with high phase I IgG. Median phase I IgG titers at diagnosis and peak titers in patients with proven chronic Q fever were significantly higher than those for patients with probable and possible chronic Q fever. The positive predictive values for proven chronic Q fever, compared to possible chronic Q fever, at titers 1:1,024, 1:2,048, 1:4,096, and ≥1:8,192 were 62.2%, 66.7%, 76.5%, and ≥86.2%, respectively. However, sensitivity dropped to <60% when cutoff titers of ≥1:8,192 were used. Although our study demonstrated a strong association between high phase I IgG titers and proven chronic Q fever, increasing the current diagnostic phase I IgG cutoff to >1:1,024 is not recommended due to increased false-negative findings (sensitivity < 60%) and the high morbidity and mortality of untreated chronic Q fever. Our study emphasizes that serologic results are not diagnostic on their own but should always be interpreted in combination with clinical parameters.

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29

Anulytė, Justina, Ernesta Bužavaitė-Vertelienė, Evaldas Stankevičius, Kernius Vilkevičius, and Zigmas Balevičius. "High Spectral Sensitivity of Strongly Coupled Hybrid Tamm-Plasmonic Resonances for Biosensing Application." Sensors 22, no. 23 (December 3, 2022): 9453. http://dx.doi.org/10.3390/s22239453.

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In this study, the sensitivity to the refractive index changes of the ambient was studied on the uniform gold film (~50 nm) with a 1D photonic crystal (PC) from periodic five TiO2 (~110 nm)/SiO2 (~200 nm) bilayers and gold nano-bumps array produced by direct laser writing on the same sample. The optical signal sensitivity of hybrid plasmonic resonances was compared with traditional surface plasmon resonance (SPR) on a single gold layer. The influence of the strong coupling regime between Tamm plasmon polariton (TPP) and propagated plasmon polaritons in the hybrid plasmonic modes on the sensitivity of the optical was discussed. Recent studies have shown very high hybrid plasmonic mode sensitivity SHSPP ≈ 26,000 nm/RIU to the refractive index on the uniform gold layer; meanwhile, the introduction of gold lattice reduces the signal sensitivity, but increases the Q-factor of the plasmonic resonances. Despite this, the sensitivity to the ellipsometric parameters Ψ and Δ on the gold lattice was rather high due to the increased Q-factor of the resonances. The comparison of plasmonic resonance sensitivity to the refractive index changes of hybrid TPP-SPP mode on the uniform gold layer and traditional SPR have shown that hybrid plasmonic mode, due to a strong coupling effect, overcomes the SPR by about 27%.

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30

Ali, Naim Ben, Haitham Alsaif, Youssef Trabelsi, Muhammad Tajammal Chughtai, Vigneswaran Dhasarathan, and Mounir Kanzari. "High Sensitivity to Salinity-Temperature Using One-Dimensional Deformed Photonic Crystal." Coatings 11, no. 6 (June 14, 2021): 713. http://dx.doi.org/10.3390/coatings11060713.

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This paper aims to theoretically study the concept of a photonic salinity and temperature sensor according to a deformed one-dimensional photonic structure. The fundamental capability of the proposed sensor is studied. Simultaneously we search to optimize the thickness of the structure and to get the maximum salinity and temperature sensitivity. The structure is constructed by alternating layers of TiO2 and fused-silica P times. In the middle of the structure, a cavity containing seawater is inserted to measure its salinity and temperature. The transfer matrix method (TMM) is used to simulate the wave-transmittance spectra. It is shown that the quality factor (Q-factor) of the resonance peaks depends on the number (P) of layers. After that, the thickness of the layers is deformed by changing the deformation degree (h). The parameters P and h are optimized to get the maximal Q-factor with the minimal number of layers and structure thickness. The best sensitivity SS of the proposed salinity sensor is 558.82 nm/RFIU with a detection limit of 0.0034 RFIU. In addition, the best sensitivity ST of the designed temperature sensor is 600 nm/RFIU with a detection limit of 0.0005 RFIU.

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31

Ge, Hongyi, Li Li, Yuying Jiang, Guangming Li, Fei Wang, Ming Lv, and Yuan Zhang. "Design of High-performance Terahertz Sensor Based on Metamaterials." Journal of Physics: Conference Series 2174, no. 1 (January 1, 2022): 012001. http://dx.doi.org/10.1088/1742-6596/2174/1/012001.

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Abstract In this paper, a high-performance terahertz sensor is proposed. The sensor obtains a perfect narrow-band transmission spectrum at 3.842 THz with a Q value of 137 at the resonance frequency. The sensitivity reaches 160 GHz/RIU at the thickness of the substance to be measured of 10 μm, with good sensing performance. The results show that it has a promising application in terahertz high-sensitivity biosensing detection.

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32

Yang, Daquan, Xin Chen, Xuan Zhang, Chuwen Lan, and Ying Zhang. "High-Q, low-index-contrast photonic crystal nanofiber cavity for high sensitivity refractive index sensing." Applied Optics 57, no. 24 (August 15, 2018): 6958. http://dx.doi.org/10.1364/ao.57.006958.

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33

Siraji, Ashfaqul Anwar, and Yang Zhao. "High-sensitivity and high-Q-factor glass photonic crystal cavity and its applications as sensors." Optics Letters 40, no. 7 (March 27, 2015): 1508. http://dx.doi.org/10.1364/ol.40.001508.

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34

Widyasari, Kristin, Soomin Kim, Sunjoo Kim, and Chae Seung Lim. "Performance Evaluation of STANDARD Q COVID/FLU Ag Combo for Detection of SARS-CoV-2 and Influenza A/B." Diagnostics 13, no. 1 (December 22, 2022): 32. http://dx.doi.org/10.3390/diagnostics13010032.

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We evaluated the performance of the STANDARD Q COVID/FLU Ag Combo test (Q Ag combo test) for the detection of SARS-CoV-2, influenza A, and influenza B using a single point-of-care device compared with real-time PCR. A total of 408 individuals, 55 positives with SARS-CoV-2, 90 with influenza A, 68 with influenza B, and 195 negatives for all viruses, participated. The Q Ag combo test demonstrated a high level of sensitivity of 92.73% and a specificity of 99.49% for the detection of SARS-CoV-2. When the number of days from symptom onset (DSO) was restricted to 0<DSO≤6, the sensitivity of the Q Ag combo test to detect SARS-CoV-2 was 100%, and when the Ct value of RdRp was ≤20, the sensitivity to detect SARS-CoV-2 was 93.10%. The Q Ag combo test results also demonstrated a sensitivity of 92.22% and a specificity of 100% for influenza A, a sensitivity of 91.18%, and a specificity of 99.49% for influenza B. The agreement analysis of the Q Ag combo test with the RT-PCR results demonstrated excellent outcomes, making it useful and efficient for the detection of SARS-CoV-2, influenza A, and influenza B.

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Semouchkina, Elena, Arash Hosseinzadeh, and George Semouchkin. "Realization of High-Q Fano Resonances in Ceramic Dielectric Metamaterials for Sensing Applications." Additional Conferences (Device Packaging, HiTEC, HiTEN, and CICMT) 2013, CICMT (September 1, 2013): 000087–93. http://dx.doi.org/10.4071/cicmt-2013-wa14.

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Ceramic all-dielectric metamaterials are found to support very high Q resonances of the Fano-type, which until recently were largely attributed to the atomic physics phenomena. It is shown that proper arrangement of ceramic resonators in the metamaterial array allowsd for obtaining Q factors up to 15000. Thus high Q factors could be employed for new applications, in particular, for advanced sensing. An opportunity to design compact arrays that could be incorporated in a microwave sensor fed by a microstrip line is demonstrated. Numerical experiments have confirmed that Fano resonances in such arrays conserve high sensitivity to the dielectric permittivity of the controlled media.

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36

Wu, Z., Y. Jiao, F. Liu, Z. Ai, and Q. Zhang. "Reducing temperature sensitivity of gas measurement using chirped-modulated photoacoustic spectroscopy." Review of Scientific Instruments 93, no. 9 (September 1, 2022): 094902. http://dx.doi.org/10.1063/5.0106669.

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Resonance frequency drift caused by a change in temperature greatly limits the application of high- Q resonators with high temperature sensitivity in photoacoustic (PA) gas detection systems. In this work, a chirp-wavelength combined modulation method was designed by incorporating a real-time frequency scanning in wavelength-modulated PA spectroscopy to reduce the influence of temperature changes on measurement. Theoretical analysis shows that the chirp rate depends on the precision requirements and the cutoff frequency of the cascaded low-pass filter. Trace acetylene measurement experiment at varying temperature verified that the proposed method can significantly reduce the temperature sensitivity within a preset temperature range. Thus, this method can effectively reduce the temperature sensitivity of a high- Q resonator for improving the measurement accuracy and detection limit in trace gas detection.

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37

Gallart, Francesc, Jana von Freyberg, María Valiente, James W. Kirchner, Pilar Llorens, and Jérôme Latron. "Technical note: An improved discharge sensitivity metric for young water fractions." Hydrology and Earth System Sciences 24, no. 3 (March 6, 2020): 1101–7. http://dx.doi.org/10.5194/hess-24-1101-2020.

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Abstract. Recent virtual and experimental investigations have shown that the young water fraction Fyw (i.e. the proportion of catchment outflow younger than circa 2–3 months) increases with discharge in most catchments. The discharge sensitivity of Fyw has been defined as the rate of increase in Fyw with increasing discharge (Q) and has been estimated by the linear regression slope between Fyw and Q, hereafter called DS(Q). The combined use of both metrics, Fyw and DS(Q), provides a promising method for catchment inter-comparison studies that seek to understand streamflow generation processes. Here we explore the discharge sensitivity of Fyw in the intensively sampled small Mediterranean research catchment Can Vila. Intensive sampling of high flows at Can Vila allows young water fractions to be estimated for the far upper tail of the flow frequency distribution. These young water fractions converge toward 1 at the highest flows, illustrating a conceptual limitation in the linear regression method for estimating DS(Q) as a metric of discharge sensitivity: Fyw cannot grow with discharge indefinitely, since the fraction of young water in discharge can never be larger than 1. Here we propose to quantify discharge sensitivity by the parameter of an exponential-type equation that expresses how Fyw varies with discharge. The exponential parameter (Sd) approximates DS(Q) at moderate discharges where Fyw is well below 1; however, the exponential equation and its discharge sensitivity metric better capture the non-linear relationship between Fyw and Q and are robust with respect to changes in the range of sampled discharges, allowing comparisons between catchments with strongly contrasting flow regimes.

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38

McCormack, Oisin, Jack Dobie, Xia Zhang, and A. Louise Bradley. "Robust all-dielectric high Q-factor metasurface for sensing." EPJ Web of Conferences 287 (2023): 04020. http://dx.doi.org/10.1051/epjconf/202328704020.

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All-dielectric metasurfaces have seen a recent surge of interest as an alternative to plasmonic devices, due to low losses and desirable optical properties. High Q-factor quasi-bound state in the continuum resonances can be manufactured and manipulated via designed asymmetry in the nanostructures. The presented metasurface design, based on a slotted disk nanostructure, produces strong E-Field enhancement with good surface coverage external to the structure. The design transition from structure-in-air to structure-on-substrate in a water-based sensing medium is presented, along with the robust tunability and multiplexing potential of our fabricated resonances. Our structure maintains a high Q-factor and refractive index sensitivity over a wide wavelength range in the visible and near-IR.

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39

Erdil, Mertcan, Yigit Ozer, and Serdar Kocaman. "High-Q Slot-Mode Photonic Crystal Nanobeam Cavity Biosensor With Optomechanically Enhanced Sensitivity." IEEE Journal of Selected Topics in Quantum Electronics 25, no. 2 (March 2019): 1–6. http://dx.doi.org/10.1109/jstqe.2018.2880592.

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40

Wang, Wu-Deng, Li Zheng, and Jian-Guang Qi. "High Q-factor multiple Fano resonances for high-sensitivity sensing in all-dielectric nanocylinder dimer metamaterials." Applied Physics Express 12, no. 7 (June 4, 2019): 075002. http://dx.doi.org/10.7567/1882-0786/ab206a.

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41

Deng, Chao-Sheng, Ming-Jun Li, Jie Peng, Wen-Liang Liu, and Jian-Xin Zhong. "Simultaneously high-Q and high-sensitivity slotted photonic crystal nanofiber cavity for complex refractive index sensing." Journal of the Optical Society of America B 34, no. 8 (July 17, 2017): 1624. http://dx.doi.org/10.1364/josab.34.001624.

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42

Truong, Anh Hoang, Hayato Sone, Tomoyuki Kawakami, and Sumio Hosaka. "Fabrication of Hole-Type Microcantilevers Using FIB and its Evaluations." Key Engineering Materials 534 (January 2013): 251–56. http://dx.doi.org/10.4028/www.scientific.net/kem.534.251.

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A high sensitive mass biosensor using a piezoresistive hole-type microcantilever has been developed. To optimize the cantilever shape for high sensitivity easily, we demonstrate frame-type cantilevers with holes on the surface fabricated by Focused Ion Beam (FIB) method and evaluate their sensitivity in both air and liquid. Resonance frequency of hole-type cantilevers increased about 20% and 40% in air and in water, respectively. On the other hand, while Q value decreased from 10% to 30% in air, it increased sharply from 0% to 50% in water with increasing of hole-size. Especially, when we increased the frame size from 0.5 µm to 2.5 µm, resonance frequency changing and Q value changing in water were 60% and 125%, respectively. However, the Q value of large hole (36x60µm2) in water inversely decreased due to the decline in rigidity. The sensitivity of hole-type cantilever of Δm/Δf(hole-size = 12x12μm2; frame-size = 2.5μm) was 23.1 fg/Hz, 10 times smaller than the conventional type cantilever.

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43

Sitoe, Nádia, Júlia Sambo, Neuza Nguenha, Jorfelia Chilaule, Imelda Chelene, Osvaldo Loquiha, Chishamiso Mudenyanga, Sofia Viegas, Jane Cunningham, and Ilesh Jani. "Performance Evaluation of the STANDARDTM Q COVID-19 and PanbioTM COVID-19 Antigen Tests in Detecting SARS-CoV-2 during High Transmission Period in Mozambique." Diagnostics 12, no. 2 (February 12, 2022): 475. http://dx.doi.org/10.3390/diagnostics12020475.

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(1) Background: Laboratory-based molecular assays are the gold standard to detect SARS-CoV-2. In resource-limited settings, the implementation of these assays has been hampered by operational challenges and long turnaround times. Rapid antigen detection tests are an attractive alternative. Our aim is to evaluate the clinical performance of two SARS-CoV-2 rapid antigen tests during a high transmission period. (2) Methods: A total of 1277 patients seeking SARS-CoV-2 diagnosis were enrolled at four health facilities. Nasopharyngeal swabs for rapid antigen and real time PCR testing were collected for each patient. Sensitivity, specificity, positive and negative predictive values, misclassification rate, and agreement were determined. (3) Results: The overall sensitivity of Panbio COVID-19 was 41.3% (95% CI: 34.6–48.4%) and the specificity was 98.2% (95% CI: 96.2–99.3%). The Standard Q had an overall sensitivity and specificity of 45.0% (95% CI: 39.9–50.2%) and 97.6% (95% CI: 95.3–99.0%), respectively. The positive predictive value of a positive test was 93.3% and 95.4% for the Panbio and Standard Q Ag-RDTs, respectively. A higher sensitivity of 43.2% and 49.4% was observed in symptomatic cases for the Panbio and Standard Q Ag-RDTs, respectively. (4) Conclusions: Despite the overall low sensitivity, the two evaluated rapid tests are useful to improve the diagnosis of symptomatic SARS-CoV-2 infections during high transmission periods.

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44

Wu, Pinghui, Shuangcao Qu, Xintao Zeng, Ning Su, Musheng Chen, and Yanzhong Yu. "High-Q refractive index sensors based on all-dielectric metasurfaces." RSC Advances 12, no. 33 (2022): 21264–69. http://dx.doi.org/10.1039/d2ra02176e.

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A high-sensitivity refractive index sensor excited by the 2D periodic TiO2 dielectric grating structure. The nanosensor can excite guided-mode resonance with a 0.19 nm ultra-narrow linewidth. Low loss all-dielectric metasurface allows ultra-sensitive biosensor detection.

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45

França, Danilo Alves de, Mateus de Souza Ribeiro Mioni, Felipe Fornazari, Nássarah Jabur Lot Rodrigues, Lucas Roberto Ferreira Polido, Camila Michele Appolinario, Bruna Letícia Devidé Ribeiro, et al. "Comparison of Three Serologic Tests for the Detection of Anti-Coxiella burnetii Antibodies in Patients with Q Fever." Pathogens 12, no. 7 (June 26, 2023): 873. http://dx.doi.org/10.3390/pathogens12070873.

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The performance of a commercial immunofluorescence assay (IFA commercial), an in-house immunofluorescence assay (IFA in-house) and an indirect enzyme-linked immunosorbent assay (ELISA) were evaluated in the detection of antibodies anti-C. burnetii in the serum of Q fever patients and persons without the disease. For the study, seropositive and seronegative samples for Q fever (n = 200) from a serum bank of the Instituto Adolfo Lutz in Brazil were used. Commercial IFA was considered in this study as the gold standard for diagnosing Q fever. The in-house IFA demonstrated good agreement with the commercial test, showing high sensitivity (91%) and specificity (97%) compared to the gold standard, with a Kappa coefficient of 0.8954. The indirect ELISA test showed lower agreement with the gold standard, showing low sensitivity (67%), although the specificity of the technique was high (97%) and the Kappa coefficient was moderate (0.6631). In-house IFA is an excellent alternative for diagnosing Q fever.

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46

Sharma, N. G., Sundararajan T., and G. S. Singh. "Thermoelastic Damping Based Design, Sensitivity Study and Demonstration of a Functional Hybrid Gyroscope Resonator for High Quality Factor." Giroskopiya i Navigatsiya 29, no. 1 (2021): 70–96. http://dx.doi.org/10.17285/0869-7035.0057.

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The most critical element of Hemispherical Resonator Gyroscope (HRG) is the high quality factor (Q-factor) mechanical resonator. This paper discusses the role of thermoelastic damping (TED) on effective Q-factor. Finite element method (FEM) is used to solve this highly coupled field problem involving vibration, solid mechanics, heat transfer and thermodynamics. The major contribution of this paper is the sensitivity analysis of the effect of material property, operating temperature and dimensions to arrive at macro scale resonator configuration. Hybrid hemispherical-cylindrical configuration is proposed by studying the performance parameters such as effective mass and angular gain.The uniqueness of the present work is the sensitivity study of ultra thin film coating (volume fraction of 0.01%), coating variations and different coating configurations. The coating can reduce the Q-factor by a few orders compared to uncoated shell. It has been found that coating material selection and coating configuration are very important factors. Another significance of the present work is the realization and detailed characterization of the hybrid fused silica resonator. Thin film gold coating is done on the 3D surfaces of the realized precision resonator. Detailed coating characterization is carried out using sophisticated instruments. Very fine balancing to the order of a few mHz is achieved after coating. Q-factor measurement of the coated resonator is carried out using LDV and achieved a few millions in the final functional hybrid resonator.

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47

Ramer, Georg, Mohit Tuteja, Joseph R. Matson, Marcelo Davanco, Thomas G. Folland, Andrey Kretinin, Takashi Taniguchi, et al. "High-Q dark hyperbolic phonon-polaritons in hexagonal boron nitride nanostructures." Nanophotonics 9, no. 6 (May 18, 2020): 1457–67. http://dx.doi.org/10.1515/nanoph-2020-0048.

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AbstractThe anisotropy of hexagonal boron nitride (hBN) gives rise to hyperbolic phonon-polaritons (HPhPs), notable for their volumetric frequency-dependent propagation and strong confinement. For frustum (truncated nanocone) structures, theory predicts five, high-order HPhPs, sets, but only one set was observed previously with far-field reflectance and scattering-type scanning near-field optical microscopy. In contrast, the photothermal induced resonance (PTIR) technique has recently permitted sampling of the full HPhP dispersion and observing such elusive predicted modes; however, the mechanism underlying PTIR sensitivity to these weakly-scattering modes, while critical to their understanding, has not yet been clarified. Here, by comparing conventional contact- and newly developed tapping-mode PTIR, we show that the PTIR sensitivity to those weakly-scattering, high-Q (up to ≈280) modes is, contrary to a previous hypothesis, unrelated to the probe operation (contact or tapping) and is instead linked to PTIR ability to detect tip-launched dark, volumetrically-confined polaritons, rather than nanostructure-launched HPhPs modes observed by other techniques. Furthermore, we show that in contrast with plasmons and surface phonon-polaritons, whose Q-factors and optical cross-sections are typically degraded by the proximity of other nanostructures, the high-Q HPhP resonances are preserved even in high-density hBN frustum arrays, which is useful in sensing and quantum emission applications.

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48

Liu, Wei, Xiwen Jiang, Yue Liu, and Qingsong Ma. "Bioinformatics Analysis of Quantitative PCR and Reverse Transcription PCR in Detecting HCV RNA." Current Bioinformatics 14, no. 5 (June 28, 2019): 400–405. http://dx.doi.org/10.2174/1574893613666180703103328.

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Objective:This research aimed to make comparisons of sensitivity and specificity between Quantitative real Time Polymerase Chain Reaction (Q-PCR) and Reverse Transcription PCR (RT-PCR) in detecting the ribonucleic acid (RNA) expression levels of Hepatitis C Virus (HCV).Methods:121 patients suffering from hepatitis C and 98 healthy participants with normal liver functions were identified. The venous blood collections were carried out, were subjected to detect the expression levels of HCV RNA via Q-PCR and RT-PCR. And then, the data obtained from these above two detection methods were compared, including the sensitivity and specificity.Results:In terms of Q-PCR, the positive rate of HCV RNA was 72.16%, which was significantly higher when compared with 55.26% of RT-PCR. After statistical analysis, the difference between them was statistically significant (P＜0.05). Among the healthy participants, 4 cases were false positive by means of RT-PCR, there was the possibility of missed diagnosis when the samples were evaluated by Q-PCR.Conclusion:: The Q-PCR detection technology performed well in testing HCV, with pretty high sensitivity and specificity. Nevertheless, the false negative results obtained from Q-PCR could not be avoided. In clinical practice, these above two detection methods should be referred to, in order to avoid missed diagnosis.

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49

Sainath Rao, Shilpakala, Krishna Mohan V. Ketha, and Chintamani D. Atreya. "Phage-Displayed Peptide-Q Dot Nanocrystal Combo for High-Sensitivity Bacterial Detection in Plasma." Blood 114, no. 22 (November 20, 2009): 3153. http://dx.doi.org/10.1182/blood.v114.22.3153.3153.

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Abstract Abstract 3153 Poster Board III-90 Introduction Despite improved phlebotomy practices, refrigeration of red cells, freezing of plasma and improved materials for transfusion product collection and storage, bacterial contamination of transfusion products is still a longstanding problem. Current bacterial detection tests relevant to transfusion medicine, especially for stored platelets have limitations with regard to time, specificity and sensitivity. There is a need for new and improved cost-effective high-affinity detection probes to fill this gap. In this study, using plasma spiked with Bacillus cereus 4342 and B. anthracis-Sterne as an experimental system, we identified peptides from a bacteriophage-displayed random peptide library that selectively bind and detect the Bacillus strains. By labeling the peptides with Q dot-liquid nanocrystals, the detection sensitivity of the peptides was further enhanced. Methods A commercially available bacteriophage-displayed random peptide library was screened using B. cereus 4342 as bait, using appropriate controls under stringent conditions. The screening and subsequent sequencing of the phage DNA identified two phages each containing a coding sequence for 12-amino acid peptide that are selectively capable of binding to the Bacillus. Based on the nucleic acid sequence, the two synthetic peptides with biotin tag were prepared for detection assays and to enhance the detection sensitivity further, the peptides were labeled with streptavidin-conjugated fluorescent quantum-dots (Q dots). Fluorescence was measured either by a plate reader or using a fluorescence microscope. Results The two synthetic peptides selectively bound to the Bacillus strains in both dot blot and ELISA assays. The membrane-based dot blot assay demonstrated an assay sensitivity of 103 colony forming units/ml (CFU/ml), whereas ELISA demonstrated a sensitivity of 102 CFU/ml detection limit. Fluorometry analysis of spiked plasma samples revealed that the two peptides were able to bind to B. cereus 4342 and B. anthracis Sterne and detect these bacteria in plasma at 102 CFU/ml concentrations. The peptide-Qdot combo even detected a single bacterium in fluorescence microscopy. Conclusion Overall, the results reported here validate the usefulness of affinity-selected recombinant filamentous phage-derived peptides in combination with Qdot-liquid nanocrystals as high sensitivity detection probes for bacteria in various platforms and settings relevant to the blood safety and transfusion medicine. The findings and conclusions in this abstract have not been formally disseminated by the Food and Drug Administration and should not be construed to represent any Agency determination or policy. Disclosures No relevant conflicts of interest to declare.

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50

Kanyang, Ruoying, Cizhe Fang, Qiyu Yang, Yao Shao, Genquan Han, Yan Liu, and Yue Hao. "Electro-Optical Modulation in High Q Metasurface Enhanced with Liquid Crystal Integration." Nanomaterials 12, no. 18 (September 13, 2022): 3179. http://dx.doi.org/10.3390/nano12183179.

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Electro-optical tuning metasurfaces are particularly attractive since they open up routes for dynamic reconfiguration. The electro-optic (EO) modulation strength essentially depends on the sensitivity to the EO-induced refractive index changes. In this paper, lithium niobate (LiNbO3) metasurfaces integrated with liquid crystals (LCs) are theoretically investigated. Cylinder arrays are proposed to support quasi-bound states in the continuum (quasi-BICs). The quasi-BIC resonances can significantly enhance the lifetime of photons and the local field, contributing to the EO-refractive index changes. By integrating metasurfaces with LCs, the combined influence of the LC reorientation and the Pockels electro-optic effect of LiNbO3 is leveraged to tune the transmitted wavelength and phase spectrum around the quasi-BIC wavelength, resulting in an outstanding tuning sensitivity up to Δλ/ΔV ≈ 0.6nm/V and relieving the need of high voltage. Furthermore, the proposed structure can alleviate the negative influence of sidewall tilt on device performance. The results presented in this work can foster wide application and prospects for the implementation of tunable displays, light detection and ranging (LiDAR), and spatial light modulators (SLMs).

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