Статті в журналах: "Heart Diseases Prevention"

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Gulnara, Asadova, and Djamalov Abdurakhman. "REMEDIES AND RECOMMENDATIONS CORONARY HEART DISEASES." Eurasian Journal of Medical and Natural Sciences 03, no. 02 (February 1, 2023): 224–28. http://dx.doi.org/10.37547/ejmns-v03-i02-p1-37.

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Prevention of coronary heart disease is a series of complex measures aimed at preventing the onset of the disease, the development and occurrence of possible (predictable) complications, which can be even fatal. Prevention of coronary heart disease is indicated for both sick people and healthy people who are at risk of developing the disease. Patients diagnosed with coronary heart disease are shown non-drug treatment, which is a complete or partial elimination of risk factors. Risk factors are any predisposing factors that increase the likelihood of developing or worsening a disease. Risk factors for coronary heart disease are fundamentally divided into removable and non-removable.

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Vakrilova Becheva, Maria Stamova, Angelina Georgieva Kirkova-Bogdanova, Stefka Аchkova Ivanova, Petar Jordanov Atanasov, Mariya Sevdelinova Chaneva, and Valentina Boyanova Petkova. "Prevention of cardiovascular diseases." Pharmacia 70, no. 4 (October 27, 2023): 1243–47. http://dx.doi.org/10.3897/pharmacia.70.e114071.

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Cardiovascular diseases (CVD) are socially significant diseases due to high morbidity and loss of people of working age. In Bulgaria, they are the leading cause of mortality among the population and are a consequence of the effect of cardiovascular risk factors. The draft of the National Health Strategy (NHS) 2021–2030 reports on their wide distribution, as well as on the insufficient knowledge, skills and motivation for their prevention and control. The purpose of this review is to address the prevention of cardiovascular disease, which is a significant problem worldwide. Prevention goals for patients with established cardiovascular disease and those at high risk include smoking cessation, healthy eating, physical activity, and lowering body mass index. There are various methods that are part of health promotion to reduce CVD risks. These methods include motivational interviewing, non-pharmacological means, the use of certain medications for CVD prevention, as well as physical activity. Strategies for effective primary prevention refer to engaging the patient to change their lifestyle and identifying risk factors, while secondary prevention is aimed at activities to detect the disease early and to slow down its progression. It is necessary to create a strategy for timely preventive actions with a view to preventing the negative influence of risk factors and improving people‘s heart health.

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Shakerifard, Amir, Sina Shahbazkia, and Amirreza Shahbazkia. "Prediction & Prevention of Diseases by Understanding Oral Diseases." Cognizance Journal of Multidisciplinary Studies 3, no. 8 (August 30, 2023): 937–55. http://dx.doi.org/10.47760/cognizance.2023.v03i08.023.

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One of the main keys for life health is the oral health. As a statically calculation about 20% of middle aged had gum diseases. The oral health is somehow associated with medical conditions, heart diseases, stroke, diabetes, pneumonia, and etc. the headaches and ear pains also are associated to the jaw problems. In this paper the main reasons of the dental and oral problems are discussed.

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Shaukatovna, Ismatova Marguba. "PREVENTION AND DIAGNOSIS OF CIRCULATORY DISEASES IN OLD AGE." American Journal of Medical Sciences and Pharmaceutical Research 04, no. 03 (March 1, 2022): 56–58. http://dx.doi.org/10.37547/tajmspr/volume04issue03-11.

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The heart is a biological pump that moves blood through a closed system of vessels, pumping about 6 litres of blood every minute. Age-related changes in the circulatory system in old age severely limit its adaptive capacity and create conditions for developing diseases. In old and old people, the number of active capillaries per unit area is significantly reduced. Tissues and organs cease to receive the nutrients and oxygen they need, leading to starvation and disease. Cardiovascular disease is the most common cause of death in humans.

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Asthana, Alok Kumar, Monika Asthana, and Payal Sharma. "PREVENTION OF CARDIO VASCULAR DISEASE THROUGH AYURVEDA." Asian Journal of Pharmaceutical Research and Development 6, no. 4 (August 23, 2018): 97–100. http://dx.doi.org/10.22270/ajprd.v6i4.379.

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In today's era non communicable diseases are most prevalent diseases. They are also known as chronic diseases. Cardiovascular disease (heart disease) or Hridaroga is one of them. This is a lifestyle disorder and that’s why we should always focus on a healthy lifestyle. A healthy lifestyle can reduce the risk of this lethal disease. Our various bad food habits and sedentary lifestyle are the major causes for heart disease. This article will provide all of us a brief knowledge of heart disease (hridaroga). One has correctly said “Prevention is better than cure”. So, this article will mainly focus on how we can prevent heart disease through ayurveda. Ayurveda is the best pathy to prevent lifestyle disorder. Here we will see various yoga asanas, various dietary habits, lifestyle modifications we can do to prevent the disease. Keywords: Hridaroga, hridashoola, CVD

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Kulmane, Edite, Mara Pilmane, and Romans Lacis. "Apoptosis, ANUP, Chromogranin A, PGP 9.5, Endothelins and VEGF in Acquired Heart Diseases: Review of Literature." Acta Chirurgica Latviensis 15, no. 1 (April 1, 2015): 63–72. http://dx.doi.org/10.1515/chilat-2016-0012.

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Summary According to the Centre for Disease Prevention and Control of Latvia data, in 2014 16076 latvians died from cardiovascular diseases and it is 57,03% of all deaths. Changes in myocardium of the diseased hearts are complex and pathogenesis is still not fully clear. Morphopathogenesis of cardiovascular diseases are complex molecular cell changes which include apoptosis, homeostasis regulating factors, and innervation and ischemia markers. In this article we wanted to provide an overview about apoptosis, atrial natriuretic peptide, chromogranin A, neuropeptide-containing innervation, endothelins and vascular endothelial growth factor in pathomorphology of acquired heart diseases and their clinical implications.

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Matuz-Mares, Deyamira, Héctor Riveros-Rosas, María Magdalena Vilchis-Landeros, and Héctor Vázquez-Meza. "Glutathione Participation in the Prevention of Cardiovascular Diseases." Antioxidants 10, no. 8 (July 29, 2021): 1220. http://dx.doi.org/10.3390/antiox10081220.

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Cardiovascular diseases (CVD) (such as occlusion of the coronary arteries, hypertensive heart diseases and strokes) are diseases that generate thousands of patients with a high mortality rate worldwide. Many of these cardiovascular pathologies, during their development, generate a state of oxidative stress that leads to a deterioration in the patient’s conditions associated with the generation of reactive oxygen species (ROS) and reactive nitrogen species (RNS). Within these reactive species we find superoxide anion (O2•–), hydroxyl radical (•OH), nitric oxide (NO•), as well as other species of non-free radicals such as hydrogen peroxide (H2O2), hypochlorous acid (HClO) and peroxynitrite (ONOO–). A molecule that actively participates in counteracting the oxidizing effect of reactive species is reduced glutathione (GSH), a tripeptide that is present in all tissues and that its synthesis and/or regeneration is very important to be able to respond to the increase in oxidizing agents. In this review, we will address the role of glutathione, its synthesis in both the heart and the liver, and its importance in preventing or reducing deleterious ROS effects in cardiovascular diseases.

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Haque, KMHS Sirajul. "Prevention of Rheumatic Fever and Rheumatic Heart Diseases in Bangladesh." Cardiovascular Journal 11, no. 2 (February 27, 2019): 91–92. http://dx.doi.org/10.3329/cardio.v11i2.40407.

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Plotnikova, Maria O., Irina A. Snimshchikova, Valerii I. Vishnevskij, Igor A. Saraev, Ekaterina V. Mityaeva, and Olga A. Konokotina. "Primary Prevention of Coronary Heart Disease: Issues of Concern." Актуальные проблемы медицины 47, no. 2 (June 28, 2024): 171–81. http://dx.doi.org/10.52575/2687-0940-2024-47-2-171-181.

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In the Russian Federation, cardiovascular diseases are one of the leading causes of both morbidity and mortality and high economic costs of healthcare. Early identification of risk factors for cardiovascular diseases and their primary prevention underlie the ongoing process to reduce these indicators. The purpose of this work was to conduct a clinical and epidemiological study to analyze the prevalence of risk factors for cardiovascular diseases in young and middle-aged people living in the Oryol region. Materials and methods: The prospective study included 353 young and middle-aged patients with acute forms of coronary artery disease (unstable angina and myocardial infarction) and 112 apparently healthy individuals. All respondents were assessed for cardiovascular risk factors and patient adherence to treatment, for a total of 21 parameters. Results: according to the study, it was found that among young and middle-aged patients living in the Oryol region, IHD develops against the background of traditional risk factors for cardiovascular diseases, the prevailing ones being arterial hypertension (88.6 %), sedentary lifestyle (68 %), poor nutrition (53.0 %) and alcohol consumption (52 %), their gender differences were established. Conclusion. The analysis of the frequency of occurrence of cardiovascular risk factors showed their widespread prevalence among the population, low awareness of the population and insufficient adherence of patients to treatment.

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Ermakova, M. A., and A. Yu Pinigina. "Genetic studies in multifactorial diseases." Glavvrač (Chief Medical Officer), no. 12 (December 10, 2022): 36–40. http://dx.doi.org/10.33920/med-03-2212-06.

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This article is devoted to the role of gene mutations in the development of multifactorial diseases such as arterial hypertension, coronary heart disease, and cancer, as well as to genotyping in optimizing the prevention, early diagnosis, and treatment of various pathologies in children and young people.

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Stewart, Bernard W., and Alan S. Coates. "Cancer Prevention: A Global Perspective." Journal of Clinical Oncology 23, no. 2 (January 10, 2005): 392–403. http://dx.doi.org/10.1200/jco.2005.05.132.

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This review will be restricted to measures aimed at primary prevention of cancer; reduction of the death rate through screening will not be covered. In many instances, cancer prevention is just one outcome of the benefits of good health practices, which may also benefit cardiovascular, lung, infectious, and metabolic diseases. Thus, reducing tobacco smoking will bring benefits in heart disease, neonatal and maternal health, stroke, and peripheral vascular disease as well as a variety of cancers, while dietary advice appropriate to cancer risk reduction will bring benefits in diabetes, stroke, kidney, and heart disease.

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Di Renzo, Laura, Paola Gualtieri, Giulia Frank, and Antonino De Lorenzo. "Nutrition for Prevention and Control of Chronic Degenerative Diseases and COVID-19." Nutrients 15, no. 10 (May 10, 2023): 2253. http://dx.doi.org/10.3390/nu15102253.

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Chronic degenerative diseases (CDD) are non-infectious, slow-progressing, and long-lasting diseases such as diabetes, heart disease, obesity, chronic respiratory diseases, neurodegenerative diseases, and cancer [...]

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Lüscher, Thomas F. "Prevention of non-communicable diseases and special causes of heart failure." European Heart Journal 36, no. 31 (August 14, 2015): 2019–22. http://dx.doi.org/10.1093/eurheartj/ehv303.

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Passarella, G., G. Trifirò, M. Gasparetto, G. Svaluto Moreolo, and O. Milanesi. "Disorders in Glucidic Metabolism and Congenital Heart Diseases: Detection and Prevention." Pediatric Cardiology 34, no. 4 (November 15, 2012): 931–37. http://dx.doi.org/10.1007/s00246-012-0577-0.

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Przybylska, Sylwia, and Grzegorz Tokarczyk. "Lycopene in the Prevention of Cardiovascular Diseases." International Journal of Molecular Sciences 23, no. 4 (February 10, 2022): 1957. http://dx.doi.org/10.3390/ijms23041957.

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Cardiovascular diseases (CVDs) are the leading cause of human mortality worldwide. Oxidative stress and inflammation are pathophysiological processes involved in the development of CVD. That is why bioactive food ingredients, including lycopene, are so important in their prevention, which seems to be a compound increasingly promoted in the diet of people with cardiovascular problems. Lycopene present in tomatoes and tomato products is responsible not only for their red color but also for health-promoting properties. It is characterized by a high antioxidant potential, the highest among carotenoid pigments. Mainly for this reason, epidemiological studies show a number of favorable properties between the consumption of lycopene in the diet and a reduced risk of cardiovascular disease. While there is also some controversy in research into its protective effects on the cardiovascular system, growing evidence supports its beneficial role for the heart, endothelium, blood vessels, and health. The mechanisms of action of lycopene are now being discovered and may explain some of the contradictions observed in the literature. This review aims to present the current knowledge in recent years on the preventive role of lycopene cardiovascular disorders.

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Yamaoka-Tojo, Minako, and Taiki Tojo. "Prevention of Natural Disaster-Induced Cardiovascular Diseases." Journal of Clinical Medicine 13, no. 4 (February 9, 2024): 1004. http://dx.doi.org/10.3390/jcm13041004.

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Natural disasters, such as floods and landslides caused by heavy rainfall, earthquakes, and tsunamis, can induce stress, which may contribute to the onset and aggravation of various cardiovascular diseases. The circulatory system is most susceptible to the effects of stress, and stress-related cardiovascular diseases, such as Takotsubo cardiomyopathy, pulmonary thromboembolism, hypertension, stroke triggered by increased blood pressure, and acute myocardial infarction, can occur during natural disasters. The risk of developing angina pectoris, arrhythmia, sudden cardiac death, and heart failure increases rapidly and can persist for several months. Moreover, treating cardiovascular diseases is essential during the acute phase, and continuous disease management is necessary during the chronic phase. However, disaster medical care for the victims must be given priority during natural disasters, which may cause a delay in diagnosis or access to necessary treatment for pre-existing medical conditions that could worsen or may cause death in patients with cardiovascular diseases. In this review, we summarize the predisposing factors for cardiovascular diseases that have been obtained through disasters such as major earthquakes and provide potential insights to help medical staff prevent the onset and aggravation of cardiovascular diseases during disasters.

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Dekate, Priyanka V. "AYURVEDIC APPROACH TO PREVENTION OF STROKE & HEART DISEASES FROM DIABETES MELLITUS." International Ayurvedic Medical Journal 9, no. 5 (May 15, 2021): 1027–31. http://dx.doi.org/10.46607/iamj1309052021.

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Madhumeha (Diabetes) is attracting the world as a non-infectious pandemic/epidemic. The prevalence of Diabetes is on the rise, more alarmingly in the developing country. Ranked 7th among leading causes of death. This multiplying incidence of CVS & heart diseases. Now days Ayurveda is of wise important to get swasthya, to prevent heart diseases & stroke from DM. The objectives of study are to evolve standard Ayurvedic drug & preventive measures for Madhumeha. This study is based on review of Ayurvedic Samhitas & previous research work. DM is the 6th leading cause of death in the world. Therefore, attempt should be made to balance the Dehamanas prakruti & normal state of physiological energy to prevent Diabetes Mellitus. Dinacharya (Daily regimen), Ashtavidha aahara vidhi Aayatana & herbo mineral drugs with Yogasana help to prevent diabetes & its related complication. Keyword: Madhumeha, stroke, Heart diseases.

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Dian Wahyuni. "Prevention & Control Efforts Non-Communicable Diseases (PTM); Hypertension." Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya 2, no. 1 (November 12, 2020): 145–52. http://dx.doi.org/10.32539/dies.v2i1.52.

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BALITBANG KEMENKES in 2020 release data in the form of tendency of non-communicable diseases (PTM) starting from the age of 10-14 years including increasing heart pressure. The purpose of this avenue is describing the prevention and control of hypertension. The method used by the online education seminar on health cadres in Sakatiga village, FK UNSRI fostered village since 2014. Finally, it is hoped that the community (cadres) can understand and implement efforts to prevent and control hypertension in the form of routinely measuring blood pressure, taking hypertension medication regularly and using complementary therapies.

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Wahyuni, Dian. "Prevention & Control Efforts Non-Communicable Diseases (PTM); Hypertension." Conferences of Medical Sciences Dies Natalis Faculty of Medicine Universitas Sriwijaya 2, no. 1 (November 16, 2020): 145–52. http://dx.doi.org/10.32539/confmednatalisunsri.v2i1.50.

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BALITBANG KEMENKES in 2020 release data in the form of tendency of non-communicable diseases (PTM) starting from the age of 10-14 years including increasing heart pressure. The purpose of this avenue is describing the prevention and control of hypertension. The method used by the online education seminar on health cadres in Sakatiga village, FK UNSRI fostered village since 2014. Finally, it is hoped that the community (cadres) can understand and implement efforts to prevent and control hypertension in the form of routinely measuring blood pressure, taking hypertension medication regularly and using complementary therapies.

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Preisner, Katharina, and Svetlana Hetjens. "Risk Factors and Preventive Measures for Cardiovascular Diseases." Journal of Clinical Medicine 13, no. 11 (June 4, 2024): 3308. http://dx.doi.org/10.3390/jcm13113308.

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Background: Cardiovascular diseases are the most frequent cause of death worldwide. The aim of this study was to identify and demonstrate correlations between mortality data and etiological factors in EU countries. The relationships presented could thus provide a better understanding of etiological factors and possible points for interventions to prevent cardiovascular diseases. The focus was on the following diseases: hypertensive heart disease, atrial flutter/atrial fibrillation, myocardial infarction, and ischemic heart disease, as well as heart failure. Methods: The data in this study come from WHO databases. Connections between the mortality rates and the possible influencing factors were analyzed. The significant factors from the correlation analysis were simultaneously evaluated using a stepwise multiple regression analysis. Results: Analysis of hypertensive heart disease in women reveals the following factors to be significant: drug expenses, health expenses on gross domestic product, and smoking. For men, population density, first admission to a drug treatment center, and drug expenses per person emerged as important factors. Admission to drug treatment centers and length of hospitalization were significant factors for atrial fibrillation and flutter. Fine dust pollution was the most important factor in heart failure. The most important influencing factor for myocardial infarction and ischemic heart disease is nitrogen dioxide concentration. For women, the second highest value is health expenses, followed by the number of outpatient contacts per year. For men, outpatient contacts are in second place. Conclusions: Prevention measures must be taken by the government. The extent to which population density has an influence on cardiovascular diseases should be examined in more detail. In order to reduce the number of initial admissions to drug treatment centers, behavioral prevention related to drug use could be improved.

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RANJAN NAYAK, Dr NIHAR. "Early Prediction and Prevention of Lifestyle Diseases." INTERANTIONAL JOURNAL OF SCIENTIFIC RESEARCH IN ENGINEERING AND MANAGEMENT 08, no. 01 (January 13, 2024): 1–10. http://dx.doi.org/10.55041/ijsrem28093.

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Helping people with diabetes early and stopping it from getting worse is really good for them. It can make them live longer and have a better life. It could also save money for society and health-care companies. To deal with the growing problem of diabetes, the International Diabetes Federation brought together a group of experts in 2006 to talk about how to prevent and understand the disease. The main purpose of the workshop and this document was to stop diabetes in both rich and poor countries. The IDF wants to lower the chance of heart problems in people who are more likely to get diabetes. They have a plan to prevent diabetes by managing things that can be changed to lower the risk, and they are focusing on two groups of people: those at high risk and everyone else. Being motivated to live a healthy lifestyle is important for preventing and managing diabetes. People are motivated by their thoughts, bodies, and surroundings, which scientists have been studying for the last 25 years. In this article, we will look at and think about what we know about what makes people do things and how it relates to their lifestyle. We will pay special attention to people with diabetes or obesity

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Yun, Sun-Hee, Byung-Gyu Park, Eun-Young Jung, Ji-Yeon Kwon, Yeon-Kyung Park, and Hea-Jeong Kim. "Factors Affecting the Practice of Corona Virus Disease-19 Prevention Activities in Patients With Heart Diseases in Korea." Clinical Nursing Research 31, no. 4 (February 14, 2022): 713–23. http://dx.doi.org/10.1177/10547738211068140.

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This study was conducted in a cross-sectional correlation design to identify factors affecting the practice of COVID-19 prevention activities in patients with heart diseases. A convenience sample of 195 patients with heart diseases from one tertiary teaching hospital completed questionnaires with items from the characteristics of these participants, their knowledge, attitude, and practice related to COVID-19 prevention activities. Participants’ knowledge, attitude, and practice for COVID-19 prevention were relatively high but there was a significant difference in the degree of practice of COVID-19 prevention activities according to the characteristics of the participants. The higher the level of their knowledge and the more positive their attitude, the higher their practice. Attitude and information check about COVID-19 prevention were factors that influenced the practice of COVID-19 prevention activities, with an explanatory power of 32%. This study can help motivate and actively encourage COVID-19 prevention practices.

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Morya, Rimpy, and Someet Singh. "Prediction model of heart diseases based on hybrid model." Journal of Physics: Conference Series 2327, no. 1 (August 1, 2022): 012071. http://dx.doi.org/10.1088/1742-6596/2327/1/012071.

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Abstract Heart diseases are crucial cause of global death. Premature detection of heart diseases and uninterrupted analysis decreases the death rate. The detection of heart diseases using various machine learning algorithm is implemented for analysis of the heart attack in minimum time. Machine learning plays a very important role in the prevention of diseases and huge comprehension a health record. Recent trend in machine learning methodology being wield in contemporary evolution in different sector of internet of things. There is different algorithm in machine learning, which is analysis of heart diseases along with different accuracy. The purpose of this research to develop machine learning model to detect the heart diseases. In this a hybrid algorithm is proposed using combination of KNN and logistic regression algorithm. Furthermore, a protype is developed which consist of set of sensors to monitor the timely for prediction or analysis of heart attack.

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Naureen, Irum, Aisha Saleem, Muhammad Naeem, Noor-e.-Maryam Bilal, Ghulam Mujtaba Hassan, Muhammad Shafiq, Mudassar Hussain, and Syed Roohullah. "Effect of Exercise and Obesity on Human Physiology." Scholars Bulletin 8, no. 1 (January 24, 2022): 17–24. http://dx.doi.org/10.36348/sb.2022.v08i01.003.

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Physical activity and exercise on a regular basis can help you stay healthy, energetic, and independent as you age. Exercise is essential in preventing health problems such as heart disease and stroke. Many studies have demonstrated the health benefits of regular exercise. This report examines the evidence regarding the health benefits of exercise across the board. Physical activity and exercise can help to lower stress and anxiety, enhance happy neurotransmitters, promote self-confidence, boost brain function, improve memory, and strengthen our muscles and bones. It also aids in the prevention and treatment of heart disease, obesity, blood sugar swings, cardiovascular disease, and cancer. It also aids in the prevention and treatment of heart disease, obesity, blood sugar swings, cardiovascular disease, and cancer. Regular physical activity has been shown the useful in the primary and secondary prevention of a variety of chronic diseases (e.g., cardiovascular disease, diabetes, cancer, hypertension, obesity, depression, and osteoporosis) as well as premature death.

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Xia, David. "The Research of Influence Factors that lead to Heart Disease." Highlights in Science, Engineering and Technology 72 (December 15, 2023): 686–92. http://dx.doi.org/10.54097/grvgtm49.

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Heart disease is one of the common diseases, and it is the disease with the highest mortality. Although there are many studies in the field of heart disease, including genetic aspects, environmental aspects and so on, most of them are single-factor studies. Therefore, this paper will establish a Probit regression model, based on 11 factors that may induce heart disease, and make a statistical analysis on the health status of 400,000 people collected in 2020. It is concluded that smoking, stroke, different walking, gender, age category, diabetes, Asthma, Kidney disease and skin cancer will have a significant positive impact on Heart Disease, and Physical Activity will have a significant negative impact on Heart Disease. However, Alcohol Drinking does not affect the Heart Disease. The results of this paper can provide a more comprehensive factor analysis direction for preventing heart disease, to do a good job of prevention, reduce the prevalence of diseases and reduce mortality.

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Christle, Jeffrey W., Steven G. Hershman, Jessica Torres Soto, and Euan A. Ashley. "Mobile Health Monitoring of Cardiac Status." Annual Review of Biomedical Data Science 3, no. 1 (July 20, 2020): 243–63. http://dx.doi.org/10.1146/annurev-biodatasci-030220-105124.

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Cardiovascular diseases (CVDs) are responsible for more deaths than any other cause, with coronary heart disease and stroke accounting for two-thirds of those deaths. Morbidity and mortality due to CVD are largely preventable, through either primary prevention of disease or secondary prevention of cardiac events. Monitoring cardiac status in healthy and diseased cardiovascular systems has the potential to dramatically reduce cardiac illness and injury. Smart technology in concert with mobile health platforms is creating an environment where timely prevention of and response to cardiac events are becoming a reality.

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Heljić, Bećir, Zelija Velija-Ašimi, and Mehmed Kulić. "The Statins in Prevention of Coronary Heart Diseases in Type 2 Diabetics." Bosnian Journal of Basic Medical Sciences 9, no. 1 (February 20, 2009): 71–76. http://dx.doi.org/10.17305/bjbms.2009.2860.

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We aimed to determine whether the administration of statins to type 2 diabetics without pre-existing CHD reduced the incidence of CHD and their effects on cholesterol and CRP levels. All the participants were carefully interviewed, clinically examined, and laboratory tested to exclude conditions likely to provoke an inflammatory response that was an exclusion criterion. Exclusion criteria: Serious heart, liver or kidney problems, history of renal transplant, recent history of drug or alcohol abuse, HbA1c>10%, blood pressure >140/90mmHg, BMI >35 kg/m2, triglycerides >3,0mmol/dm3. 95 obese diabetics (mean age 60,9 years and BMI=31,59 kg/m2, diabetes duration more than 10 years) without pre-existing CHD, were included in the analysis and were randomized to simvastatin (25 female and 20 male used 40 mg simvastatin daily) or placebo (30 female and 20 male) group. After six months, simvastatin significantly lowered CRP levels by 19%, (p<0,01), cholesterol levels by 18%, TG levels by 8%, LDL levels by 20% and VLDL levels by 17%, whereas there was no change with placebo. After one year the difference sustained between groups. Coronary events were rarely in the simvastatin group (6,6%) than in the placebo group (14%). Coronary revascularizations were 4 in the placebo group and 1 in the simvastatin group. Rate of stroke was more often in the placebo group (18%) than in the simvastatin group (8,8%). So, reduction of acute CHD events is for 7,4% in the simvastatin group. Positive correlation was between CRP and CVD (r=0,29). Statin therapy reduced the risk of coronary hearth disease in diabetics without CHD.

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Actaiyeva, Leilim, Kuat Abzaliyev, Simbat Abzaliyeva, and Gulum Aldangarova. "Characteristics of woman`s heart with disorder of coronary circulation." Heart, Vessels and Transplantation 3, Issue 1 (December 4, 2018): 16. http://dx.doi.org/10.24969/hvt.2018.98.

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We present review of current evidence on ischemic heart disease in women. The risk factors, clinical manifestations, diagnosis and treatment and prevention of ischemic heart diseases in women are discussed.

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Chhetri, Vivek Thapa, Resham G.C., Sanup Chaudhary, Sachin Timilsina, and Subash Gautam. "Pests, pathogens, pathogenic diseases, and diseases control strategies of sal (Shorea robusta) in Nepal." Archives of Agriculture and Environmental Science 6, no. 2 (June 25, 2021): 210–17. http://dx.doi.org/10.26832/24566632.2021.0602013.

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Sal (Shorea robusta) is one of the most indispensable species in Nepal, both ecologically and economically. This paper aims to provide updated guidance for the management and protection of this species in the future from various pests and pathogens. We reviewed 38 articles from Google Scholar and Research gate with keywords "Shorea robusta”, “Hoplocerambyx spinicornis”, “Polyporus shoreae”, “Heart rot”. S. robusta has the most insect fauna among the forest tree species. Out of the 346 insects reported on S. robusta, around 155 species of insects are associated with living trees. Hoplocerambyx spinicornis is the most destructive insect pest, wreaking havoc on S. robusta. Polyporous shoreae is the main cause of root rot in S. robusta, and spreads through root contact or root grafting. Heart rot in S. robusta is caused by the fungi Hymenochaete rubiginosa, Fomes caryophylli, and F. fastuosus. During the harvesting of S. robusta, the majority of the tree was observed to be faulty, resulting in a large amount of waste wood. The best way to determine the pathogen's "Achilles' heel" is to consider its life cycle. The Nepalese famous saying "prevention is better than cure" may be applicable in the management of S. robusta insect pests and pathogens. The current paper critically addresses these issues and argues the need for an improvised package of activities for insect pests, pathogens, prevention, and their control.

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Nkomo, V. T. "Epidemiology and prevention of valvular heart diseases and infective endocarditis in Africa." Heart 93, no. 12 (December 12, 2006): 1510–19. http://dx.doi.org/10.1136/hrt.2007.118810.

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Maron, Barry J. "Sudden Cardiac Death in Genetic Heart Diseases and the Promise of Prevention." Revista Española de Cardiología (English Edition) 63, no. 3 (March 2010): 257–60. http://dx.doi.org/10.1016/s1885-5857(10)70056-6.

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Infante, Teresa, Dario Costa, and Claudio Napoli. "Novel Insights Regarding Nitric Oxide and Cardiovascular Diseases." Angiology 72, no. 5 (January 22, 2021): 411–25. http://dx.doi.org/10.1177/0003319720979243.

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Nitric oxide (NO) is a powerful mediator with biological activities such as vasodilation and prevention of vascular smooth muscle cell proliferation as well as functional regulation of cardiac cells. Thus, impaired production or reduced bioavailability of NO predisposes to the onset of different cardiovascular (CV) diseases. Alterations in the redox balance associated with excitation–contraction coupling have been identified in heart failure (HF), thus contributing to contractile abnormalities and arrhythmias. For its ability to influence cell proliferation and angiogenesis, NO may be considered a therapeutic option for the management of several CV diseases. Several clinical studies and trials investigated therapeutic NO strategies for systemic hypertension, atherosclerosis, and/or prevention of in stent restenosis, coronary heart disease (CHD), pulmonary arterial hypertension (PAH), and HF, although with mixed results in long-term treatment and effective dose administered in selected groups of patients. Tadalafil, sildenafil, and cinaguat were evaluated for the treatment of PAH, whereas vericiguat was investigated in the treatment of HF patients with reduced ejection fraction. Furthermore, supplementation with hydrogen sulfide, tetrahydrobiopterin, and nitrite/nitrate has shown beneficial effects at the vascular level.

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Tressera-Rimbau, A., S. Arranz, M. Eder, and A. Vallverdú-Queralt. "Dietary Polyphenols in the Prevention of Stroke." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–10. http://dx.doi.org/10.1155/2017/7467962.

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Polyphenols have an important protective role against a number of diseases, such as atherosclerosis, brain dysfunction, stroke, cardiovascular diseases, and cancer. Cardiovascular diseases are the number one cause of death worldwide: more people die annually from cardiovascular diseases than from any other cause. The most important behavioural risk factors of heart disease and stroke are unhealthy diet, physical inactivity, tobacco use, and excess alcohol intake. The dietary consumption of polyphenols has shown to be inversely associated with morbidity and mortality by cardio- and cerebrovascular diseases. It is well-known that the protective effects of polyphenolsin vivodepend on the grade how they are extracted from food and on their intestinal absorption, metabolism, and biological action with target tissues. The aim of this review was to summarise the relation between polyphenols of different plant sources and stroke in human intervention studies, animal models, and in vitro studies.

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Alam, Md Entekhab Ul, Md Nurul Amin, Md Jawadul Haque, Farzana Hasan, Milon Kumar Haldar, Nelofar Yasmin, Shathi Kumar Rawson Kamal Md Abu Syem Shah Amanath Ullah, et al. "Awareness of Rural People about Prevention of Non-Communicable Diseases." Ibrahim Cardiac Medical Journal 10, no. 1-2 (March 15, 2021): 27–32. http://dx.doi.org/10.3329/icmj.v10i1-2.54000.

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Background & Objective: Non-communicable diseases, particularly diabetes, hypertension and ischemic heart diseases have created an epidemic situation worldwide. Bangladesh is also in the grip of the menace. The only way to get rid of the menace is prevention of these diseases which demands awareness against the diseases. This study was undertaken to assess the level of knowledge of adult people of Puthia Upazila regarding prevention of the seclected non-communicable diseases (NCDs). Methods: The study was carried out in the Department of Community Medicine Rajshahi Medical College, Rajshahi over a period of 2 months from April 2018 to May 2018. All adult people (18 years onwards) residing in the rural area of Puthia Upazila were the respondents (study population) in this study. The survey invited the adult individuals to participate in the study. A total of 1001 individuals voluntarily responded to participate in the study. Of them 648(64.7%) were free from the NCDs and were interviewed to assess their level of knowledge on prevention of selected NCDs. A self-administered questionnaire containing the variables of interest for evaluating knowledge was used. Result: Two-thirds (68.2%) of the respondents were 30–50 years old with mean age of the respondents being 44.3(range: 25-90) years. Males outnumbered females by 11:9. Over half (54%) informed that they had little knowledge and 10.7% were familiar with the NCDs. Around half held the view that diabetes, hypertension, ischemic heart diseases and stroke were NCDs/chronic diseases. Approximately 70% told that the NCDs were on a rising trend. Regarding causes of chronic diseases, the respondents told excess intake of fat and sedentary life-style (67.9%), intake of excess CHO (54.2%), indulgence in smoking (68.2%), less intake of vegetables and fruits (57.4%), excess or additional salt intake (50.5%) and family history of NCD (44.1%). Regarding prevention of NCDs, around 70% were in favor of adopting healthy dietary behaviour and avoiding too much fatty food, followed by regular exercise (71.2%), avoiding or giving up smoking (70.8%) and avoiding or giving up taking extra salt (57.9%). Conclusion: The study concluded that the people of Puthia Upazilla are aware more or less about the selected NCDs (diabetes, hypertension, ischemic heart diseases and stroke). They are also aware that these diseases are increasing. Around two-thirds of the people are aware about the risk factors of these non-communicable diseases and the ways to prevent them. Ibrahim Card Med J 2020; 10 (1&2): 27-32

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Rejali, Laila, Stephanie Ozumerzifon, Hashem Nayeri, and Sedigheh Asgary. "Risk reduction and prevention of cardiovascular diseases: biological mechanisms of lycopene." Bioactive Compounds in Health and Disease 5, no. 10 (November 1, 2022): 202. http://dx.doi.org/10.31989/bchd.v5i10.975.

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Background and aims: The conservational effects of dietary interventions as advantageous instruments in the primary and secondary prevention of cardiovascular disease (CVD) have gotten more attention in recent years. Numerous nutritional epidemiological studies have highlighted the ability of diets to decrease costly care and treatments as well as adverse side effects from standard treatments. Lycopene is a non-pro-vitamin A carotenoid that is present in tomatoes, processed tomato products, and different fruits like watermelon, autumn olive, gac, pink grapefruit, pink guava, papaya, sea buckthorn, and wolfberry. As one of the most powerful antioxidants among dietary tetraterpenoids, lycopene can also assist in lowering the risk of early death and extending life in patients with heart disease. By reducing the destructive effects of free radicals along with total and “bad” LDL cholesterol levels while increasing “good” HDL cholesterol, lycopene holds the power to reduce the risk factors of heart disease. Several studies have investigated a reduction of oxidized-LDL (oxLDL) cholesterol levels following lycopene consumption which supports these claims and suggests the conceivable function of lycopene in the blockage of oxidative stress-associated CVD. A negative correlation between serum lycopene concentration and mortality of people with metabolic syndrome was found. Over 10 years, researchers observed a 39% decreased chance of premature death in individuals with the metabolic disease who had the highest blood concentrations of lycopene. Lycopene’s protective impacts are especially beneficial in those with low blood antioxidant levels or high levels of oxidative stress. This includes older adults, smokers, and diabetic individuals or other vascular disorders. Lycopene intake has been thought to reduce the risk of obesity, insulin resistance, and diabetes mellitus.Lycopene acts as an antihypertensive agent by impeding the angiotensin-converting enzyme and improving the production of nitric oxide (NO) in the endothelium. The purpose of this review is to summarize the possible mechanisms of lycopene in the prevention of CVD. Keywords: Lycopene, Risk factors of heart disease, Antioxidants, Carotenoids, Cardio-metabolic, Insulin resistance

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H. R. Rao, Gundu. "Early Diagnosis of Risks and Management of Cardiometabolic Diseases: A Case Study." Open Access Journal of Cardiology 8, no. 1 (2024): 1–15. http://dx.doi.org/10.23880/oajc-16000199.

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The case study presented underscores the importance of early identification of metabolic risks, effective management, and lifestyle modifications in preventing clinical complications associated with cardiometabolic diseases (CMDs). The individual in the study, a South Asian immigrant, experienced the development of essential hypertension in his mid-50s, leading to left ventricular hypertrophy (LVH) and mild diastolic dysfunction. However, through proactive measures such as early diagnosis of metabolic risks, robust management of cardiovascular disease (CVD), adherence to a heart-healthy diet, and lifestyle changes, he was able to avoid major clinical complications of diabetes and maintain overall well-being until the age of 87. The key takeaways from this case study align with broader public health initiatives aimed at addressing the global epidemic of metabolic diseases. The multifaceted and intricate nature of this problem requires a comprehensive approach that considers various factors contributing to the rising prevalence of these diseases. Primary prevention strategies, which focus on identifying and mitigating risk factors for CMDs before the onset of vascular disease, play a crucial role in curbing the epidemic. The success observed in this case study, highlights the potential impact of proactive management and lifestyle interventions, in preventing and mitigating the progression of cardiometabolic diseases. It emphasizes the need for increased awareness, early screening, and ongoing monitoring of individuals at risk. Additionally, promoting heart-healthy diets and encouraging lifestyle modifications, such as regular physical activity and stress reduction, are essential components of a holistic approach to cardiometabolic health. Despite the positive outcomes demonstrated in this case, the article acknowledges that the global response to preventing both communicable and non-communicable diseases has been tepid, with varying levels of enthusiasm for developing primary prevention strategies across different nations. Addressing this challenge requires coordinated efforts at the individual, community, and policy levels to promote a culture of preventive healthcare. In conclusion, the findings of this case study contribute to the growing body of evidence supporting the efficacy of early diagnosis of metabolic risks, effective management, and lifestyle modifications in preventing clinical complications associated with cardiometabolic diseases. The lessons learned from individual cases can inform broader public health initiatives and underscore the importance of a proactive and comprehensive approach to address the escalating prevalence of metabolic diseases globally

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Cherkashin, Dmitry V., Ruslan G. Makiev, Pavel Yu Kirichenko, Andrey E. Alanichev, and Vitaliy V. Gornov. "A NEW STRATEGY TO IMPROVE THE PREVENTION OF CARDIOVASCULAR DISEASES IN THE ARMED FORCES OF THE RUSSIAN FEDERATION." Bulletin of the Russian Military Medical Academy 19, no. 3 (December 15, 2017): 34–39. http://dx.doi.org/10.17816/brmma12178.

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We study the morbidity and mortality from cardiovascular diseases in the Russian Federation and in the Armed Forces. Studied the advantages and disadvantages of a modern complex of measures for the prevention, early detection, treatment of diseases of the heart and blood vessels in the Armed Forces, as well as prevention strategies for cardiovascular diseases in the Russian Federation. Presents the stages and activities implemented strategies to increase effectiveness of prevention of cardiovascular disease in military personnel. The proposals for improving the early diagnosis and prevention of cardiovascular diseases in the armed forces, developed on the basis of the severity of factors influencing the risk of the development, prevalence and course of cardiovascular disease in military personnel (bibliography: 24 refs).

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Tian, Rong, Wilson S. Colucci, Zoltan Arany, Markus M. Bachschmid, Scott W. Ballinger, Sihem Boudina, James E. Bruce, et al. "Unlocking the Secrets of Mitochondria in the Cardiovascular System." Circulation 140, no. 14 (October 2019): 1205–16. http://dx.doi.org/10.1161/circulationaha.119.040551.

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Mitochondria have emerged as a central factor in the pathogenesis and progression of heart failure, and other cardiovascular diseases, as well, but no therapies are available to treat mitochondrial dysfunction. The National Heart, Lung, and Blood Institute convened a group of leading experts in heart failure, cardiovascular diseases, and mitochondria research in August 2018. These experts reviewed the current state of science and identified key gaps and opportunities in basic, translational, and clinical research focusing on the potential of mitochondria-based therapeutic strategies in heart failure. The workshop provided short- and long-term recommendations for moving the field toward clinical strategies for the prevention and treatment of heart failure and cardiovascular diseases by using mitochondria-based approaches.

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Khvatova, Yulia G., and Andrey V. Chernyshev. "Risk factors and prevention of coronary heart disease." Tambov Medical Journal 6, no. 2 (2024): 92–107. http://dx.doi.org/10.20310/2782-5019-2024-6-2-92-107.

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Abstract. This research presents the results of systematizing knowledge on risk factors for coronary heart disease, classifying them and analyzing possible ways of prevention. The research shows that risk factors are not only a medical, but also a social issue, since the society, social conditions, and government policy are an integral part of the life of every individual. The relevance of this research is justified by the high proportion of cardiovascular diseases, among which coronary heart disease predominates. The incidence of coronary heart disease is inextricably linked with lifestyle, so its modification is the first major issue that requires modern solutions. Systematization of the available scientific data on risk factors for coronary heart disease will help doctors, including primary care, to actively identify and systematically influence risk factors for coronary heart disease, using an individual approach to each patient. Classification into modifiable, non-modifiable and social risk factors creates a clear understanding of the existing risk factors. That gives an idea of those risk factors that can be influenced and should be taken into account when stratifying the risk of cardiovascular pathology and selecting relevant modern therapy for a particular patient.

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E.A., Babak, Ivanov S.V, Karpenko Y.A., and Soroka E.S. "ASPECTS OF PREVENTION OF CARDIOVASCULAR DISEASES AS THE MOST COMMON PATHOLOGY IN THE RUSSIAN FEDERATION AND THE REPUBLIC OF CRIMEA." Natural resources of the Earth and environmental protection 2, no. 1 (March 5, 2021): 11–17. http://dx.doi.org/10.26787/nydha-2713-203x-2021-2-1-11-17.

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The data analyzed in this article relate to each region and each city. Cardiovascular diseases have been identi-fied as the main non-communicable cause of death not only in Crimea, but also in all regions of the Russian Federation. According to who, about 17.5 million people die from cardiovascular diseases every year, which is 31% of all deaths in the world. Many diseases of the heart and blood vessels can be prevented through a vari-ety of non-specific prevention measures. The purpose of this work is to study the most common as-pects of prevention of cardiovascular diseases in the Re-public of Crimea and the Russian Federation. Tasks: Study the statistics of cardiovascular diseases and find out the most common ones. Identify the most common causes of cardiovascular dis-eases. Learn about the risk factors that lead to CVD complica-tions. Consider prophylactic measures to prevent diseases of the heart and blood vessels.

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Pavlik, Gábor. "A szív edzettségi jeleinek a szerepe a szív-keringési betegségek megelőzésében." Cardiologia Hungarica 51, no. 5-6 (2021): 342–47. http://dx.doi.org/10.26430/chungarica.2021.51.5.342.

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The sedentary way of life collects victims mostly through the disorders of the cardiovascular system; the most frequent causes are the ischemic heart disease and the stroke. The training-induced characteristics of the athlete’s heart have well defined roles in the better exercise performance at the young age, and in the prevention of the heart diseases in the older age. The left ventricular hypertrophy in the young age results in a better endurance performance, in the older age, however, regular physical activity protects against pathological hypertrophy. The improved coronary circulation is mainly a consequence of the regular physical activity in the younger age, results in a less frequent incidence of ischemic heart diseases, and the milder consequences of myocardial infarctions. The better diastolic function, improved distensibility helps a more economic function of the heart both in the young and in the older age. The most important manifestation of the modified autonomous regulation is the lower heart rate at rest and during physical load, resulting in a more economic cardiac function and better coronary circulation. Several mechanisms are involved in the prevention of the stroke; a leading role is the prevention of the high blood pressure. Regular physical exercise decreases blood pressure by 3-4 mmHg in normotensive subjects and by cca. 10 mmHg in hypertensive patients. The training of the heart is the endurance training, minimum 20 min monotone, cyclic movement.

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Achirda, Nur, Liza Laela Abida, Assyifa Fitri Anggraeni, Fatimah Zahra nur Layyina, Millenia Khairunisa, and Robby Daniel Fahreza. "FISIOTERAPI KOMUNITAS DALAM PENCEGAHAN RISIKO VASCULAR DISEASE DI KLUB JANTUNG SEHAT LESTARI RW 015 KELURAHAN JATISAMPURNA." Jurnal Pengabdian Masyarakat Fisioterapi dan Kesehatan Indonesia 3, no. 01 (June 7, 2024): 18–25. http://dx.doi.org/10.59946/jpmfki.2024.290.

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Background: Cardiovascular disease is a disease that attacks the body's cardiovascular system including the heart and blood vessels. One of the cardiovascular diseases is stroke. The importance of physical activity and education can increase awareness of body health and knowledge about stroke and vascular disease prevention. This can have a positive effect in maximizing the body's recovery optimally. Purpose: This community physiotherapy aims to determine the level of knowledge of the community at the Sustainable Heart Club regarding Vascular Disease. Methods: Community physiotherapy activities are carried out in 4 activities, namely problem identification, identification of intervention solutions, provision of interventions and prevention of potential problems. Results: There was a significant increase in the level of knowledge of respondents regarding stroke and vascular disease and their prevention. Conclusion: Aerobic exercise and providing education related to preventing the risk of vascular disease can have a positive effect on society. Keywords: Elderly, cardiovascular disease, stroke, physical activity, education

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Chaulin, Aleksey M., and Dmitry V. Duplyakov. "Environmental factors and cardiovascular diseases." Hygiene and sanitation 100, no. 3 (April 16, 2021): 223–28. http://dx.doi.org/10.47470/0016-9900-2021-100-3-223-228.

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Introduction. New advances in the diagnosis and treatment of cardiovascular diseases (CVD), as practice shows, are not able to significantly improve the statistical indicators of morbidity and mortality of CVD. This fact indicates that there are additional factors and mechanisms that are important to consider, both for prevention and for the most optimal management of patients. Recently, the relationship between environmental and lifestyle factors with CVD has been actively studied. However, despite understanding the relationship between environmental factors and various diseases, including CVD, the mechanisms by which specific factors increase or decrease the risk of developing CVD are not yet fully understood, and a number of studies are contradictory. The aim of our work was to generalize existing data on the impact of such critical environmental factors as air pollution and solar insolation on the cardiovascular system, as well as to comprehensively discuss the mechanisms by which these environmental factors can participate in the development and progression of CVD. To achieve our work’s goal, we analyzed modern foreign literature using the PubMed database. Conclusion. According to numerous experimental and clinical studies, air pollution and solar insolation deficiency play an essential role in developing CVD and the aggravation of patients with various CVD (atherosclerosis, hypertension, coronary heart disease, heart failure, myocardial infarction, and stroke). Thus, air pollution and lack of solar insolation can be considered as critical risk factors for CVD. Future research should focus on the study and establishment of specific pathogenetic mechanisms by which environmental factors affect the cardiovascular system’s health to develop effective treatment and prevention measures.

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Vandenberg, Jamie I., Matthew D. Perry, and Adam P. Hill. "Recent advances in understanding and prevention of sudden cardiac death." F1000Research 6 (August 31, 2017): 1614. http://dx.doi.org/10.12688/f1000research.11855.1.

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There have been tremendous advances in the diagnosis and treatment of heart disease over the last 50 years. Nevertheless, it remains the number one cause of death. About half of heart-related deaths occur suddenly, and in about half of these cases the person was unaware that they had underlying heart disease. Genetic heart disease accounts for only approximately 2% of sudden cardiac deaths, but as it typically occurs in younger people it has been a particular focus of activity in our quest to not only understand the underlying mechanisms of cardiac arrhythmogenesis but also develop better strategies for earlier detection and prevention. In this brief review, we will highlight trends in the recent literature focused on sudden cardiac death in genetic heart diseases and how these studies are contributing to a broader understanding of sudden death in the community.

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Barykina, Kristina, Zainab Ismailova, Konstantin Karanov, Liana Bizhoeva, Elena Turovinina, and Alexander Markov. "Prevention of Complications of Cardiac Pathologies." Journal of Complementary Medicine Research 14, no. 2 (2023): 117. http://dx.doi.org/10.5455/jcmr.2023.14.02.18.

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The article discusses the prevention of complications of cardiac pathologies. As the author points out, complications associated with heart disease can be serious and even dangerous. Therefore, it is important to consult a doctor in a timely manner and conduct regular medical examinations in order to prevent or detect possible heart problems early. It is also important to lead a healthy lifestyle, including proper nutrition, regular exercise and smoking cessation. In addition to individual prevention measures, it is necessary to regularly develop and implement State programs for the prevention of cardiovascular diseases, which include educational campaigns and subsidizing activities to improve overall health, such as subsidies for physical activity and anti-obesity programs. Large-scale campaigns are also needed to reduce the level of smoking and control alcohol consumption. Keywords: cardiological pathologies, complications, liver

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Hameed, Ekhlas Khalid, and Laith Thamer Al-Ameri. "Lifestyle Medicine: A Promising tool to Restoring Health." AL-Kindy College Medical Journal 18, no. 3 (December 31, 2022): 165–66. http://dx.doi.org/10.47723/kcmj.v18i3.932.

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Lifestyle Medicine is the application of evidence-based lifestyle approaches for the prevention, treatment, and even the reversal of lifestyle-related chronic diseases such as diabetes, hypertension, heart disease, obesity, polycystic ovarian diseases, dementia, arthritis, and cancers

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Gaebel, Ralf, Cajetan Lang, Praveen Vasudevan, Larissa Lührs, Katherine Athayde Teixeira de Carvalho, Eltyeb Abdelwahid, and Robert David. "New Approaches in Heart Research: Prevention Instead of Cardiomyoplasty?" International Journal of Molecular Sciences 24, no. 10 (May 19, 2023): 9017. http://dx.doi.org/10.3390/ijms24109017.

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Cardiovascular diseases are the leading cause of death in industrialized nations. Due to the high number of patients and expensive treatments, according to the Federal Statistical Office (2017) in Germany, cardiovascular diseases account for around 15% of total health costs. Advanced coronary artery disease is mainly the result of chronic disorders such as high blood pressure, diabetes, and dyslipidemia. In the modern obesogenic environment, many people are at greater risk of being overweight or obese. The hemodynamic load on the heart is influenced by extreme obesity, which often leads to myocardial infarction (MI), cardiac arrhythmias, and heart failure. In addition, obesity leads to a chronic inflammatory state and negatively affects the wound-healing process. It has been known for many years that lifestyle interventions such as exercise, healthy nutrition, and smoking cessation drastically reduce cardiovascular risk and have a preventive effect against disorders in the healing process. However, little is known about the underlying mechanisms, and there is significantly less high-quality evidence compared to pharmacological intervention studies. Due to the immense potential of prevention in heart research, the cardiologic societies are calling for research work to be intensified, from basic understanding to clinical application. The topicality and high relevance of this research area are also evident from the fact that in March 2018, a one-week conference on this topic with contributions from top international scientists took place as part of the renowned “Keystone Symposia” (“New Insights into the Biology of Exercise”). Consistent with the link between obesity, exercise, and cardiovascular disease, this review attempts to draw lessons from stem-cell transplantation and preventive exercise. The application of state-of-the-art techniques for transcriptome analysis has opened new avenues for tailoring targeted interventions to very individual risk factors.

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Abe, Masanobu, Akihisa Mitani, Atsushi Yao, Kazuto Hoshi, and Shintaro Yanagimoto. "Systemic Disorders Closely Associated with Malocclusion in Late Adolescence: A Review and Perspective." International Journal of Environmental Research and Public Health 19, no. 6 (March 14, 2022): 3401. http://dx.doi.org/10.3390/ijerph19063401.

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Oral diseases such as dental caries and periodontal disease are reported to be associated with various systemic diseases such as heart disease, respiratory disease, diabetes, rheumatism, and metabolic syndrome, thus increasing the importance of prevention and early treatment [...]

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Skvortsov, V. V., and N. N. Ivanov. "Risk factors of cardiovascular diseases in the work of nursing staff." Meditsinskaya sestra 26, no. 4 (July 19, 2024): 35–42. http://dx.doi.org/10.29296/25879979-2024-05-07.

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Based on long-term prospective monitoring of almost healthy people and significant epidemiological analyses around the world, a scientific concept of risk factors for coronary heart disease was created. This concept determines the development of coronary heart disease and in practice has become the basis on which today’s provisions for the prevention of this pathology are based. At the moment, more than 200 possible risk factors have been identified that have an effect on the progression of coronary heart disease. Despite all this about 50–60, there is in fact a connection with the formation of pathology. For the activity of a doctor, a significantly smaller number of risk factors are important [1, 2].

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Sun, Wei, Caixia Liu, Qiuhui Chen, Ning Liu, Youyou Yan, and Bin Liu. "SIRT3: A New Regulator of Cardiovascular Diseases." Oxidative Medicine and Cellular Longevity 2018 (2018): 1–11. http://dx.doi.org/10.1155/2018/7293861.

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Cardiovascular diseases (CVDs) are the leading causes of death worldwide, and defects in mitochondrial function contribute largely to the occurrence of CVDs. Recent studies suggest that sirtuin 3 (SIRT3), the mitochondrial NAD+-dependent deacetylase, may regulate mitochondrial function and biosynthetic pathways such as glucose and fatty acid metabolism and the tricarboxylic acid (TCA) cycle, oxidative stress, and apoptosis by reversible protein lysine deacetylation. SIRT3 regulates glucose and lipid metabolism and maintains myocardial ATP levels, which protects the heart from metabolic disturbances. SIRT3 can also protect cardiomyocytes from oxidative stress-mediated cell damage and block the development of cardiac hypertrophy. Recent reports show that SIRT3 is involved in the protection of several heart diseases. This review discusses the progress in SIRT3-related research and the role of SIRT3 in the prevention and treatment of CVDs.

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