Добірка наукової літератури з теми "Hard tissue reconstruction"

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Статті в журналах з теми "Hard tissue reconstruction"

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Tosiriwatanapong, Terawat, and Weerachai Singhatanadgit. "Zirconia-Based Biomaterials for Hard Tissue Reconstruction." Bone and Tissue Regeneration Insights 9 (January 1, 2018): 1179061X1876788. http://dx.doi.org/10.1177/1179061x18767886.

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Implantable biomaterials are increasingly important in the practice of modern medicine, including fixative, replacement, and regeneration therapies, for reconstruction of hard tissues in patients with pathologic osseous and dental conditions. A number of newly developed advanced biomaterials have been introduced as promising candidates for tissue reconstruction. Among these, zirconia-based biomaterials have gained attention as a biomaterial for hard tissue reconstruction due to superior mechanical properties and good chemical and biological compatibilities. This review summarizes the types of zirconia, advantages of zirconia-based biomaterials for hard tissue reconstruction including bone and dental tissues, responses of tissue and cells to zirconia, and surface modifications for enhanced bioactivity of zirconia. Current and future applications of zirconia-based biomaterials for bone and dental reconstruction, ie, medical implanted devices, dental prostheses, and biocompatible osteogenic scaffolds, are also discussed.
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Lautenschlager, Stephan. "DIGITAL RECONSTRUCTION OF SOFT-TISSUE STRUCTURES IN FOSSILS." Paleontological Society Papers 22 (September 2016): 101–17. http://dx.doi.org/10.1017/scs.2017.10.

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AbstractIn the last two decades, advances in computational imaging techniques and digital visualization have created novel avenues for the study of fossil organisms. As a result, paleontology has undergone a shift from the pure study of physically preserved bones and teeth, and other hard tissues, to using virtual computer models to study specimens in greater detail, restore incomplete specimens, and perform biomechanical analyses. The rapidly increasing application of these techniques has further paved the way for the digital reconstruction of soft-tissue structures, which are rarely preserved or otherwise available in the fossil record. In this contribution, different types of digital soft-tissue reconstructions are introduced and reviewed. Provided examples include methodological approaches for the reconstruction of musculature, endocranial components (e.g., brain, inner ear, and neurovascular structures), and other soft tissues (e.g., whole-body and life reconstructions). Digital techniques provide versatile tools for the reconstruction of soft tissues, but given the nature of fossil specimens, some limitations and uncertainties remain. Nevertheless, digital reconstructions can provide new information, in particular if interpreted in a phylogenetically grounded framework. Combined with other digital analytical techniques (e.g., finite element analysis [FEA], multibody dynamics analysis [MDA], and computational fluid dynamics [CFD]), soft-tissue reconstructions can be used to elucidate the paleobiology of extinct organisms and to test competing evolutionary hypotheses.
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Harris, Christopher M., and Robert Laughlin. "Reconstruction of Hard and Soft Tissue Maxillofacial Defects." Atlas of the Oral and Maxillofacial Surgery Clinics 21, no. 1 (March 2013): 127–38. http://dx.doi.org/10.1016/j.cxom.2012.12.004.

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Kim, Roderick Y., Momofiyin Sokoya, Fayette C. Williams, Tom Shokri, and Yadranko Ducic. "Role of Free Tissue Transfer in Facial Trauma." Facial Plastic Surgery 35, no. 06 (November 29, 2019): 584–89. http://dx.doi.org/10.1055/s-0039-1700880.

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AbstractFor large composite traumatic defects of the head and neck, free tissue transfer presents a reconstructive allowing for the reconstitution of both form and function. Furthermore, the ability to provide bulk, soft, and hard tissue, as well as immediate dental rehabilitation, makes free tissue transfer an efficient and attractive option for head and neck reconstruction. Herein, we discuss the utility of free tissue transfer in facial trauma, its problems, complications, and controversies.
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Badhey, Arvind K., and Mohemmed N. Khan. "Palatomaxillary Reconstruction: Fibula or Scapula." Seminars in Plastic Surgery 34, no. 02 (May 2020): 086–91. http://dx.doi.org/10.1055/s-0040-1709431.

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AbstractPalatomaxillary reconstruction presents a unique challenge for the reconstructive surgeon. The maxillofacial skeleton preserves critical aerodigestive functions—it provides a stable hard palate to support mastication and separate the nasal and oral cavities, and buttress support to provide adequate midface contour. Free tissue transfer has become a routine part of the reconstructive ladder in managing palatomaxillary defects. While there is a wide variety of options for bony reconstruction within the head and neck, the fibula and the scapula, and their variations, have become two of the most commonly used options for midface reconstruction. This review will discuss the advantages and disadvantages of both in specific regard to reconstruction of the palatomaxillary area.
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Tanaka, Shinzo, Manabu Minoyama, and Masahiro Tanabe. "Reconstruction of the Arytenoid with Hard Tissue after Partial Laryngectomy." Practica Oto-Rhino-Laryngologica 95, no. 3 (2002): 281–86. http://dx.doi.org/10.5631/jibirin.95.281.

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Marx, Robert E. "Principles of hard and soft tissue reconstruction of the jaws." Journal of Oral and Maxillofacial Surgery 49, no. 8 (August 1991): 46. http://dx.doi.org/10.1016/0278-2391(91)90553-x.

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Jung, S. Heredero, G. Sánchez Aniceto, I. Zubillaga Rodríguez, R. Gutiérrez Diaz, and I. I. García Recuero. "Posttraumatic Frontal Bone Osteomyelitis." Craniomaxillofacial Trauma & Reconstruction 2, no. 2 (May 2009): 61–66. http://dx.doi.org/10.1055/s-0029-1202594.

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We present the clinical case of a patient with open bilateral frontal sinus fractures who developed a frontal osteomyelitis. A review of the problem and management ascending to the different alternatives for central anterior skull base defects and fronto-orbital reconstruction is also presented. After extensive radical debridement of the necrotic bone, final reconstruction of the skull base was performed by using a rectus abdominis free flap. A custom-made hard tissue replacement implant was used for the fronto-orbital reconstruction. Extensive debridement is required for the treatment of frontal osteomyelitis. An appropriate isolation of the skull base from the upper aerodigestive system must be obtained to prevent continuous infectious complications. Free flaps are especially useful for skull base reconstruction when traditional methods are not available or have failed because of the lack of available tissue for vascularized reconstruction. Custom-made alloplastic implants are a good reconstructive option for large fronto-orbital defects once the infection is gone and vascularized tissue has been transferred.
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Wang, Li Ping, Jiang Hui Dong, Long Wang, Hong Jian Liao, and Rong Lin Liang. "Study on Three-Dimensional Reconstruction of the Individualized Maxillofacial Soft and Hard Tissue." Applied Mechanics and Materials 543-547 (March 2014): 2137–40. http://dx.doi.org/10.4028/www.scientific.net/amm.543-547.2137.

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The three-dimensional modeling of the maxillofacial soft and hard tissue has a great significance for the study of facial growth and development, diagnosis and treatment of facial deformity, postoperative face prediction and treatment evaluation. The key technology of the maxillofacial soft and hard tissue reconstruction is described.
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Yoshihara, Kumiko, Yasuhiro Yoshida, Noriyuki Nagaoka, Daisuke Fukegawa, Satoshi Hayakawa, Atsushi Mine, Mariko Nakamura, et al. "Nano-controlled molecular interaction at adhesive interfaces for hard tissue reconstruction." Acta Biomaterialia 6, no. 9 (September 2010): 3573–82. http://dx.doi.org/10.1016/j.actbio.2010.03.024.

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Дисертації з теми "Hard tissue reconstruction"

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Czarnecki, Jarema S. "Engineered carbon-based scaffolds for hard and soft tissue repair, reconstruction or regeneration." University of Dayton / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1386953861.

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chiara, d'elia. "IMPORTANCE OF SOFT AND HARD TISSUE MANAGEMENT ON THE AESTHETICS AND LONG TERM STABILITY AT IMPLANT SITE." Doctoral thesis, Università di Siena, 2019. http://hdl.handle.net/11365/1072174.

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Missing teeth in anterior maxilla represents one of the most challenging therapy in implant dentistry, as providing a “perfect” aesthetic results of the final restoration may include several biological variables. The aesthetic outcome of implant supported restoration is markedly influenced by the natural appearance of the dental restoration with the surrounding teeth and soft tissues; that implies that the peri implant soft tissue should be in harmony with the mucosa around the adjacent teeth and that the implant crown should be in balance with the neighbouring dentition in a natural way ( Meijer et al, 2005; Meijndert et a, 2007). The restoration of a single edentulous tooth in anterior maxilla by implant placement, was introduced as a predictable procedure in the early nineties (Jemt et al, 1991); it rapidly became a viable and effective prosthodontic alternative to conventional fixed bridgework, resin bonded restoration or partial removable dentures ( Belser et al, 1998; Belser et al, 2004). Long term studies have reported high implant survival rate for single tooth implants placement, demonstrating excellent functional success rate (Scheller et al, 1998; Romeo et al 2002; Naert et al, 2002; Kois 2004); however an implant that is osteointegrated does not alway corresponds with an aesthetic success and unlike the past, today the patients expectations degree is greater. It has been suggested that today patients use to evaluate their final restoration comparing it with the contra- lateral natural tooth as the gold standard ( Chang et al, 1999). Therefore, in order to satisfy patients’ increasing expectations, clinicians who approach aesthetic demanding clinical cases, should strive to focus not only on the prosthetic parameters but also to gingival parameters, such as soft tissue blending and ideal papilla form. Thus, in the aesthetic area, the evaluation of the success rate of single implant therapy is not only based on survival rate criteria ( Albrektsson et al, 1986), but even more by the long term quality and stability of soft and hard tissue. One of the most important key factor is a proper treatment planning prior to implant placement, requiring both objective and subjective criteria related to hard and soft tissue management (Belser et al, 1998). As a consequence of this shift in aesthetic consciousness both by patients and clinicians, the well known and traditional success criteria, ( Albrecktsson et al, 1986) have been gradually replaced by new ones: firstly, Smith and Zarb included the necessity of aesthetic variables for both patients and clinicians in order to evaluate successful results ( Smith & Zarb, 1989 ). Further, many Authors proposed different tools and indices in order to objectively assess and quantify prosthetic results and peri implant soft tissue outcomes ( Belser et al, 1998; Furhauser et al, 2005; Mejiert et al, 2005; Benic 2012). Various implant treatment procedure have been proposed in order to achieve optimal aesthetic prior or at implant placement ( Esposito et al, 2012): these surgical strategies include both soft tissue and hard tissue augmentation techniques. In some clinical situations, it might be possible to obtain good aesthetic results only by manipulating or augmenting soft tissues; particularly, many surgical approaches have been proposed to modify flap designs or to rebuild and correct the height of the papilla between a single implant and the adjacent tooth or the peri implant connective tissue fill between two adjacent implants. Recently, many Authors focused on this topic, suggesting that to better predict the aesthetic outcome of the implant supported restoration, it would be beneficial to identify the ideal vertical distances between the bone crest and the interproximal contact point to create an adequate papilla volume (Jung et al, 2018). It was concluded that the papilla height between an implant and a tooth is mainly affected by the clinical attachment level of the tooth; furthermore, other factors may influence the papilla volume and filling of the interproximal embrasure, such as tooth- and implant- related factors and at the same time surgical-related factors , such as stage vs simultaneous procedure or submerged vs transmucosal healing. The Authors concluded that, to reduce the risk of aesthetic complication, an appropriate periodontal examination should be performed during the clinical surgical planning, to correctly assess the clinical attachment level at the adjacent teeth. Nevertheless, based on the available weak evidence, it is not possible to identify a threshold distance able to predict a complete papilla fill. Another controversial issue, when evaluating the soft tissue management, is the need of an adequate band of keratinised mucosa around dental implants to improve their long term prognosis. Many Authors strongly recommend the use of soft tissue augmentation techniques to increase the width of keratinised mucosa , in order to promote peri implant health, without firm evidence supporting these statements ( Wennstrom 1994; Chung 2006; Roos- Jansaker 2006). Further studies reported, however, that a wider keratinised mucosa may be crucial to preserve soft and hard tissue stability at implant site ( Bouri et al, 2008), being a key factor in long term maintenance of dental implants ( Kim et al, 2009), resulting in a better oral hygiene and less recession over time ( Schrott et al, 2009). A recent systematic review ( Thoma et al, 2018) assessed the importance of soft tissue grafting procedure in order to improve peri implant heath, enhancing both mucosal thickness and keratinised mucosa width. On the other hand, even when approaching severe ridge deficiences of the anterior or posterior maxilla, the success largely relies on primary wound closure during and after the surgical procedure ( Wang et al, 2006). These challenging clinical scenarios requires an adequate soft tissue management in order to prevent early membrane or graft exposure that may lead to clinical failures ( Tonetti et al, 2006)
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Ferroni, Letizia. "Ricostruzione in vitro di 'SOFT AND HARD TISSUE' a partire da cellule staminali adulte: tecniche di ingegneria dei tessuti ed analisi di citogenetica molecolare." Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422096.

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The aim of this study was the in vitro reconstruction of "soft and hard tissue". Adult Stem Cells were seeded onto three-dimensional scaffolds with appropriate differentiation factors. In particular, the following constructs were prepared: (a) hyaluronic acid or fibrin scaffolds seeded with Skin Precursors Cells (SKPs) and Adipose Derived Stem Cells (ADSCs) for the regeneration of nervous tissue; (b) hydroxyapatite scaffold seeded with ADSCs to regenerate a vascularized bone tissue substitute; (c) hyaluronic acid biomaterial seeded with Dental Pulp Stem Cells (DPSCs) to generate a dental pulp-like tissue. First of all, the differentiation of stem cells was assessed in monolayer cultures by means of immunofluorescence analysis. Subsequently, the same differentiation conditions were applied on three-dimensional cultures. Proliferation test, scanning electron microscopy morphological analysis and gene expression analysis by Real Time PCR were performed at different time points. Furthermore, the genetic stability of the differentiated cells was verified by means of karyotype and CGH array analysis. The overall data showed: (a) the neuronal and glial commitment of SKPs and ADSCs on hyaluronic acid and fibrin scaffolds and the chromosomal stability of these three-dimensional cultures. (b) The concurrent osteogenic and endothelial commitment of ADSCs on hydroxyapatite scaffold and the in vitro generation of a tissue-engineered bone graft with a great osteointegration potential. (c) The concurrent glial, neuronal, and endothelial commitment of DPSCs onto non-woven hyaluronic acid scaffold, defining a possible model to restore the nervous and vascular components of the dental pulp tissue.
In questo lavoro sono stati ricostruiti in vitro 'soft and hard tissue' seminando Cellule Staminali Adulte su supporti tridimensionali in presenza di opportuni fattori differenziativi. In particolare, sono stati preparati i seguenti costrutti: (a) tessuto nervoso a partire da cellule staminali di pelle (SKP) e tessuto adiposo (ADSC) seminate su un supporto a base di acido ialuronico o fibrina; (b) tessuto osseo vascolarizzato utilizzando ADSC seminate su scaffold a base di idrossiapatite e (c) tessuto simil-dentale associando le cellule staminali della polpa dentale (DPSC) a un biomateriale a base di acido ialuronico. Lo studio ha previsto una fase preliminare in monostrato, in cui il differenziamento delle cellule staminali è stato valutato mediante analisi di immunofluorescenza. Stabilita la plasticità  delle cellule staminali ai fattori differenziativi, sono stati effettuati gli esperimenti nelle tre dimensioni. A diversi tempi, i costrutti sono stati sottoposti a test di proliferazione, ad analisi morfologica mediante microscopia elettronica a scansione e ad analisi dell'espressione genica mediante Real Time PCR. Inoltre sono state condotte analisi di citogenetica mediante cariotipo e CGH array per verificare la stabilità  genetica delle cellule durante il differenziamento. I dati raccolti hanno mostrato: (a) il differenziamento neuronale e gliale delle SKP e delle ADSC su supporti a base di acido ialuronico e fibrina mediante un processo che non altera l’assetto cromosomico delle cellule differenziate. (b) Il co-differenziamento osteogenico ed endoteliale delle ADSC su supporti a base di idrossiapatite e la generazione in vitro di un sostituto osseo bioingegnerizzato privo di alterazioni geniche e dalla promettente osteointegrazione. (c) Un possibile modello per la rigenerazione della polpa dentale che associa le DPSC a un supporto tridimensionale a base di acido ialuronico sottoforma di tessuto non tessuto, dove il co-differenziamento gliale, neuronale ed endoteliale delle DPSC favorisce la rigenerazione della componente nervosa e vascolare del tessuto pulpare.
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Книги з теми "Hard tissue reconstruction"

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Almeshal, Obaid, Salah Aldekhayel, and Feras Alshomer, eds. Soft Tissue Reconstruction of the Hand: Loco-regional and Distant Flaps Selection and Approach. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9945-0.

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Sabapathay, S. Raja, and Roderick Dunn. Reconstruction. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757689.003.0007.

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The principles of upper limb reconstruction are to perform careful wound excision, fix the skeleton, reconstruct vessels, nerves, tendons, and bone as required (either immediate or delayed), and to obtain primary healing of the soft tissues with healthy vascularized tissue. This enables early movement—ideally, supervised by hand therapists—and generally results in a good outcome. In particular, delayed healing and immobility can lead to long-term morbidity. We provide a general overview of the principles of surgical incisions in the hand, wound care, and suturing, and discuss the use of skin grafts and flaps in the upper limb. We describe reconstruction of the different areas of the upper limb, along with detailed sections on digital and thumb reconstruction.
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Glynn Bolitho, D. Tumours and hand reconstruction. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199550647.003.006012.

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♦ Hand tumours are common♦ The vast majority are benign♦ Soft tissue – commonest Giant cell tumour of tendon sheath. Treatment marginal excision♦ Bone – commonest – Enchondroma. Treatment – leave if incidental or currette +/− bone grafting♦ Malignant – need full work up with detailed clinical examination, investigation, and planning in a multidisciplinary meeting♦ Treatment is wide/radical excision often with partial amputation +/− plastic surgical reconstruction.
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Warwick, David, Roderick Dunn, Erman Melikyan, and Jane Vadher. Reconstruction. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199227235.003.0007.

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Principles of reconstruction of upper limb injuries 192Surgical incisions 196Suturing 197Wound care 200Soft tissue healing 203Grafts 204Flaps 208Useful flaps for upper limb reconstruction 212Reconstruction from axilla to hand 218Reconstruction of digits 220Thumb reconstruction 222•...
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Stephens, Paul, and Roderick Dunn. Soft tissue injuries of the hand. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757689.003.0006.

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Soft tissue injuries of the hand are common and may present variously to therapists, general practice, emergency departments, or surgeons. Simple injuries can be treated without specialist input, but the majority of hand trauma should be referred to dedicated hand surgery centres. Diagnostic error and delayed specialist treatment may lead to poor outcomes and long-term disability. This chapter provides a detailed overview for non-specialists, as well as an aide memoire for hand surgeons and hand therapists. It includes the principles of general wound care, the management of nail injuries, the treatment of extravasation and high-pressure injection injuries, and gunshot wounds. We describe different levels of upper limb amputation, as well as microvascular reconstruction (both replantation and revascularization). We also cover thermal injuries (burns and frostbite), trauma-induced cold sensitivity, and factitious injury.
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Sebastin, Sandeep J., and David Mk Tan. Soft Tissue Reconstruction for Digital Defects, an Issue of Hand Clinics. Elsevier, 2020.

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Esthetics in implantology : strategies for soft and hard tissue therapy. Quintessence, 2010.

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Agarwal, Anil, Neil Borley, and Greg McLatchie. Plastic and reconstructive surgery. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199608911.003.0011.

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In this chapter on plastic and reconstructive surgery, the reconstructive ladder is introduced. Debridement of a complex wound, burns, and infected collection in hand are described. Steps of taking a split-skin graft, harvesting a full-thickness skin graft (FTSG), excision of malignant skin lesion and ganglion, tendon repair, nerve and tendon graft harvest, local skin flap, nail bed repair, repair of digital nerve and lip laceration, trigger digit repair, use of Z plasty, digital terminalization, reduction and fixation of hand fracture, insertion of tissue expander, execution of fasciocutaneous and muscle flaps, abdominoplasty, inguinal lymphadenectomy, correction of syndactyly, reconstruction of nipple, and selective fasciectomy are described. Also included is steroid injection of a scar.
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Almeshal, Obaid, Salah Aldekhayel, and Feras Alshomer. Soft Tissue Reconstruction of the Hand: Loco-Regional and Distant Flaps Selection and Approach. Springer Singapore Pte. Limited, 2022.

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Частини книг з теми "Hard tissue reconstruction"

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Smith, Miller, Fayette Williams, and Brent B. Ward. "Hard Tissue Reconstruction." In Management of Complications in Oral and Maxillofacial Surgery, 283–316. West Sussex, UK: John Wiley & Sons, Inc,., 2013. http://dx.doi.org/10.1002/9781118704493.ch13.

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Chandra, Srinivasa R., and Vijay Pillai. "Hard Tissue Reconstruction of the Maxillofacial Region." In Oral and Maxillofacial Surgery for the Clinician, 1997–2008. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_88.

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Rati, Verma, Nishant Singh, Sanjay Rai, and Shekhar Kumta. "Triply Periodic Minimal Surface-Based Porous Scaffold Design and Analysis Subjected to Hard Tissue Reconstruction." In Lecture Notes on Multidisciplinary Industrial Engineering, 955–66. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-32-9072-3_80.

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Duncan, Scott F. M., and Christopher W. Flowers. "CMC Soft Tissue Reconstruction." In Therapy of the Hand and Upper Extremity, 143–44. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14412-2_54.

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Bellemère, Philippe. "Soft Tissue Reconstructive Procedures in the Rheumatoid Wrist, Including Tendon Transfer Procedures." In Clinical Management of the Rheumatoid Hand, Wrist, and Elbow, 105–18. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-26660-2_11.

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Jacob, D’ Souza, and Boyapati Raghu. "Sarcoma of the Maxillofacial/Head and Neck Region." In Oral and Maxillofacial Surgery for the Clinician, 1893–902. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-15-1346-6_83.

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AbstractSarcomas are malignant mesenchymal tumours. They are relatively uncommon in the head and neck region. They are diverse affecting both soft and hard tissues. Multiple histological subtypes are recognised. There is considerable variation in their behaviour and response to treatment, both in adults and children. Historically, poor outcomes are due to multiple reasons such as paucity of standardised treatment approaches and the complex anatomy of the head and neck region. Nevertheless, surgery plays a key part in the management of sarcomas, both from an ablative and reconstructive viewpoint. The modern reconstructive techniques have improved quality of life for those undergoing surgical ablation.
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Ali, Hassan abbas, and Turki Alhassan. "Standard Cross-Finger (Cronin) Flap." In Soft Tissue Reconstruction of the Hand: Loco-regional and Distant Flaps Selection and Approach, 61–67. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9945-0_13.

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Alazzam, Abdullaziz S., and Abdulaziz Alhujayri. "Adipo-Fascial Flaps." In Soft Tissue Reconstruction of the Hand: Loco-regional and Distant Flaps Selection and Approach, 151–55. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9945-0_30.

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Alshenaifi, Abdulaziz, and Nawaf Alohaideb. "Reverse Radial Forearm Flap." In Soft Tissue Reconstruction of the Hand: Loco-regional and Distant Flaps Selection and Approach, 167–72. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9945-0_33.

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Al Turki, Ahmed T., and Turki Alhassan. "Intercomissural Flap." In Soft Tissue Reconstruction of the Hand: Loco-regional and Distant Flaps Selection and Approach, 83–87. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-9945-0_17.

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Тези доповідей конференцій з теми "Hard tissue reconstruction"

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Sunaguchi, Naoki, Tetsuya Yuasa, and Masami Ando. "Iterative Reconstruction for X-Ray Dark Field Imaging CT: Artifacts Reduction for Hard and Soft Mixture Tissue." In Biomedical Engineering / Robotics Applications. Calgary,AB,Canada: ACTAPRESS, 2014. http://dx.doi.org/10.2316/p.2014.818-030.

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2

Suganuma, Lisa, Hiromichi Fujie, Hiroki Sudama, Yoshihide Sato, Norimasa Nakamura, Kenji Suzuki, Yasuhiro Tanaka, and Nobuyuki Moronuki. "Nanostructure Processed on Culture Plate Improves Cell Adhesion." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53753.

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Анотація:
Ligaments and tendons have superior functions, but their healing capacities are limited. We have been developing a novel tissue-engineering technique for the repair of ligaments and tendons which involve stem cell-based self-assembled tissues (scSAT) derived from synovium[1]. For biological reconstruction of soft tissues, it is required for the scSAT to have high tensile strength. Our previous study indicted that, when the scSAT was cultured under high cell density condition, the tensile strength of the scSAT become higher than that cultured under low density condition[2]. However, the scSAT had a significant tendency to detach naturally from the culture dish with increasing cell density. Therefore, we expect that the mechanical property of the scSAT improves by enhancing the cell adhesion to culture plates. Previous studies suggested that nanostructure processed on culture dish affected cell adhesion [3, 4]. In the present study, nanostructure was processed on a silicon wafer using a nanoprocessing technology, and the structure was replicated to a polydimethylsiloxane (PDMS) plate. Human synovium-derived mesenchymal stem cells were cultured on the plate, and cell adhesion and morphological observation were performed.
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3

Medelli´n Castillo, Hugo I., and Manuel A. Ochoa Alfaro. "Development of a Tridimensional Visualization and Model Reconstruction System Based on Computed Tomographic Data." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62822.

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Анотація:
Medical image processing constitutes an important research area of the biomedical engineering since it provides accurate human body information for 3D visualization and analysis, diagnostic, surgical treatment planning, surgical training, prosthesis and implant design, wafer and surgical guides design. Computed tomography (CT) and magnetic resonance imaging (MRI) have had a great impact in the medicine since they can represent complex three dimensional (3D) anomalities or deformities. In this paper, the development of a system for tridimensional visualization and model reconstruction based on CT data is presented. The aim is to provide a system capable to assist the design process of prosthesis, implants and surgical guides by reconstructing anatomical 3D models which can be exported to any CAD program or computer aided surgery (CAS) system. A complete description of the proposed system is presented. The new system is able to visualize and reconstruct bone and/or soft tissues. Three types of renders are used: one for 3D visualization based on three planes, other for 3D surface reconstruction based on the well known marching cubes algorithm, and the other for 3D volume visualization based on the ray-casting algorithm. The functionality and performance of the system are evaluated by means of four case studies. The results have proved the capability of the system to visualize and reconstruct anatomical 3D models from medical images.
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4

Zhou, Yo-Cheng. "New application of a traditional Chinese medicinal sclerosing agent in combination with a YAG laser for the treatment of cavernous hemangioma of the eyelids and conjunctivae." In International Laser Science Conference. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/ils.1986.fe3.

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The treatment of cavernous hemangioma of eyelids and conjunctivae in the maxillo-facial region is a difficult problem. Radiotherapy, surgical excision, and cryotherapy are harmful to the eyeball and its surrounding tissue. Also, a laser beam is hard to handle when applied to the conjunctivae. A new technique of ablating these lesions using a traditional Chinese medicinal sclerosing agent, 10% liquid alumen, with a YAG laser was used to treat cavernous hemangioma of the eyelids and conjunctivae satisfactorily. Advantages of this combined therapy include: (1) superb hemostasis; (2) simplicity, safety, and effectiveness; (3) no damage to eyeball and its surrounding tissue; (4) avoidance of reconstructive procedures; and (5) minimal or no postoperative pain or other side effects.
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Ramalho, Tarciane Campos, Rafael Victor Moita Minervino, IsaIbela Campos Ramalho, Jean Fabricio de Lima Pereira, and Og Arnaud Rodrigues. "METAPLASTIC CARCINOMA OF THE BREAST WITH CHONDROID-TYPE MESENCHYMAL DIFFERENTIATION: A CASE REPORT." In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1055.

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Metaplastic breast carcinoma (MpBC) is a rare and morphologically diverse group of tumors in which a variable proportion or the entire tumor is composed of nonglandular epithelium or mesenchymal cells. It is defined by the histological presence of at least two cellular types, typically epithelial and mesenchymal components. It is composed of ductal, squamous, and/or chondroid, and spindle elements, with squamous cell carcinoma being the most frequent histological subtype. MpBC represents 0.2%–5% of all breast cancers and it is very aggressive. This type of breast cancer is typically triplenegative and is therefore not targetable with hormone therapy or anti-HER2 therapies, leaving only chemotherapeutics for management. MpBCs are known for their aggressive course and poor response to chemotherapy. PDL1/PD1 expression is a predictor of the effectiveness of immune checkpoint therapy in breast cancer. Finally, there are currently no standardized treatment guidelines specifically for MpBC2. A 42-year-old female patient, lactating, who had her only pregnancy at age 40, visited a Mastology Clinic on July 16, 2019, complaining of huge left breast pain. She did not know about her family background, as she was adopted. On physical examination, she had lactating breasts and two palpable lumps of hard consistency, contiguous, and mobile in the upper outer quadrant of the left breast, measuring 3 and 2.5 cm. Mammography described dense breasts, with no other changes and breast ultrasound revealed two solid nodules, measuring 2.7 and 0.6 cm, and a simple cyst measuring 3.4 cm, all of which were contiguous in the upper outer quadrant of the left breast — BIRADS 4. A fine-needle aspiration puncture was performed in the simple cyst, with a histopathological result of poorly differentiated malignant neoplasm with pleomorphic focus, and a core-needle biopsy, with histopathological result of breast tissue infiltrated by pleomorphic malignant neoplasm. The immunohistochemical analysis showed positive for pan cytokeratin AE1/AE3 and negative for CD45, S100, myogenin, and myodio; bringing the conclusion of poorly differentiated carcinoma, suggestive of MpBC. She received neoadjuvant chemotherapy, with doxorubicin + cyclophosphamide, but had rapid local tumor progression. A new ultrasound revealed a heterogeneous and partially delimited mass, measuring 8.8×6.1 cm — BIRADS 6. The patient underwent a left total mastectomy and axillary lymph node dissection on September 23, 2019 — without breast reconstruction, and confirmed invasive metaplastic carcinoma with chondroid-type mesenchymal differentiation, measuring 7 cm, histological grade III, nuclear grade III, associated with solid and cribriform ductal carcinoma in situ, with comedonecrosis — grade III; free surgical margins, but with axillary lymph node metastasis (8/20). The immunohistochemical analysis of the surgical specimen revealed a triple-negative carcinoma: estrogen and progesterone receptors negative, and HER2 negative. The patient had a good postoperative recovery and received radiotherapy (50 Gy). Thereafter, she received adjuvant chemotherapy with capecitabine, within which she evolved with axillary, supraclavicular, and pulmonary lymph node metastasis. The PDL1 marker showed a negative result; therefore, palliative paclitaxel and bevacizumab were prescribed. The patient rapidly evolved with worsening of the lung lesions and was hospitalized on March 9, 2020, with serious dyspnea, progressing to death on March 19, 2020.
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6

Bhabhrawala, Talib, and Venkat Krovi. "Shape Recovery From Medical Image Data Using Extended Superquadrics." In ASME 2005 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2005. http://dx.doi.org/10.1115/detc2005-84738.

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Анотація:
Rapid and representative reconstruction of geometric shape models from surface measurements has applications in diverse arenas ranging from industrial product design to biomedical organ/tissue modeling. However, despite the large body of work, most shape models have had limited success in bridging the gap between reconstruction, recognition, and analysis due to conflicting requirements. On one hand, large numbers of shape parameters are necessary to obtain meaningful information from noisy sensor data. On the other hand, search and recognition techniques require shape parameterizations/abstractions employing few robust shape descriptors. The extension of such shape models to encompass various analysis modalities (in the form of kinematics, dynamics and FEA) now necessitates the inclusion of the appropriate physics (preferably in parametric form) to support the simulation based refinement process. Thus, in this paper we discuss development of a class of parametric shape abstraction models termed as extended superquadrics. The underlying geometric and computational data structure intimately ties together implicit-, explicit- and parametric- surface representation together with a volumetric solid representation that makes them well suited for shape representation. Furthermore, such models are well suited for transitioning to analysis, as for example, in model-based non rigid structure and motion recovery or for mesh generation and simplified volumetric-FEA applications. However, the development of the concomitant methods and benchmarking is necessary prior to widespread acceptance. We will explore some of these aspects further in this paper supported with case studies of shape abstraction from image data in the biomedical/life-sciences arena whose diversity and irregularities pose difficulties for more traditional models.
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7

Assunção, Silvaleide Ataides, and Rosemar Macedo Sousa Rahal. "BENEFITS OF BREAST RECONSTRUCTION ON THE QUALITY OF LIFE OF WOMEN WITH BREAST CANCER." In Abstracts from the Brazilian Breast Cancer Symposium - BBCS 2021. Mastology, 2021. http://dx.doi.org/10.29289/259453942021v31s2071.

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Objectives: Mastectomy is the most effective form of treatment in cases of breast cancer, promoting biopsychosocial consequences to patients. Thus, the objective is to integrate and analyze data from studies carried out, highlighting the positive impact of breast reconstruction based on the available medical literature, contributing to a better understanding of the importance of such a procedure to improve the quality of the services provided. Methodology: This is a descriptive research based on a review of the medical literature available through a survey of publications from the past 12 years in the PubMed, Lilacs, and MedLine databases. The following descriptors were used: “reconstruction” AND “mammary” AND “benefits”. Results: It was noted that women who underwent breast reconstruction had a high level of satisfaction with the quality of life in the psychological and social relations domains. Most of them have a medium to a very high degree of satisfaction, suggesting that the postoperative functional adaptation was not negatively affected by the additional anatomical changes imposed by breast reconstruction. There are also benefits in the sexual life of these patients, who find a degree of satisfaction between good and excellent. In the literature, there are reports of better social interaction, job satisfaction, higher levels of satisfaction, and lower incidence of depression among women who underwent immediate reconstruction after 1 year of surgery. However, such benefits do not seem to be universally found when women undergoing immediate reconstruction are compared with those treated conservatively, with quadrantectomies or lumpectomies. Conclusion: Breast reconstruction, in addition to being a right under Law 12.802, is a procedure that reduces the sensation of mutilation and alleviates the absence of the breast. Therefore, when indicated procedures, such as prostheses, tissue expansion or flaps, after mastectomy, reinforce the woman’s self-esteem because the breast is understood in society as a fundamental characteristic for femininity.
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8

Zhang, Qingwei, Wei Zhang, Donggang Yao, Peter I. Lelkes, and Jack G. Zhou. "The Co-Continuous Micro-Porous PLLA Scaffolds and Their Application for ACL Reconstruction." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-38291.

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Anterior cruciate ligament (ACL) reconstructive surgery is a major health concern world-wide because of a large aging population and increased occurrence of sport-related damage. Tissue engineering is a rapidly growing interdisciplinary field that offers a promising new approach for ACL repair. In order to overcome the shortages of current existing surgical fixation devices, we are combining gradient cellular structure (GCS) injection molding technique and biomedical engineering to develop novel surgical fixation devices (screw, anchor, plate, pin, staple, etc.) that not only incorporate bioactive materials such as growth factors, healing drugs and cells, but have natural bone GCS structure, intended to mimic the natural bone and promote bone tissue growth and eventually eliminate the defects associated with existing surgical fixation devices. In this work, a series of novel poly-L-lactic acid (PLLA) scaffolds with micro-porous structure were prepared by injection molding an immiscible polymer blend, with spatially controlled thermal conditioning to adjust the phase size from core to surface. The produced scaffolds were observed under SEM, which shows a co-continuous structure was created successfully through our method. The biocompatibility and the feasibility of produced micro-porous structural PLLA and PLLA/HA scaffolds as a matrix supporting cell growth tested by culturing murine osteoblasts cell line (7F2) for up to 9 days were assessed by Alamar Blue™ assay, which showed that the manufacturing process had no negative effects on cell proliferation. The cell attachment, spreading, migration and proliferation to confluence were assessed by fluorescent nuclear staining with Hoechst 33258. In order to evaluate the functional and cell biological applicability of the micro-porous structural PLLA scaffolds, a subcutaneous biodegradation test was performed through rat model for 1 week and 1 month time period, respectively. Our results showed that the micro-porous structural PLLA scaffolds are non-toxic, and they showed a mild foreign body reaction and complete fibrous encapsulation after implantation. Well created interconnected porous structure and biocompatibility suggest great potential of the micro-porous PLLA scaffolds in application for ACL reconstruction.
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9

Nacarino-Meneses, Carmen, and Anusuya Chinsamy. "Reconstructing the Biology of Extinct Horses from Hard-Tissue Histology: The Case of a South African Hipparionine <sup>†</sup>." In 1st International Electronic Conference on Biological Diversity, Ecology and Evolution. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/bdee2021-09454.

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10

Clarke, Cody J., Simeon R. Eberz, and Ephraim F. Zegeye. "An Affordable and Portable Palpable System for Sensing Breast Tissue Abnormalities." In ASME 2020 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/smasis2020-2273.

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Анотація:
Abstract Due to the high cost of equipment and lack of trained personnel, manual palpation is a preferred alternative breast examination technique over mammography. The process involves a thorough search pattern using trained fingers and applying adequate pressure, with the objective of identifying solid masses from the surrounding breast tissue. However, palpation requires skills that must be obtained through adequate training in order to ensure proper diagnosis. Consequently, palpation performance and reporting techniques have been inconsistent. Automating the palpation technique would optimize the performance of self-breast examination, optimize clinical breast examinations (CBE), and enable the visualization of breast abnormalities as well as assessing their mechanical properties. Various methods of reconstructing the internal mechanical properties of breast tissue abnormalities have been explored. However, all systems that have been reported are bulky and rely on complex electronic systems. Hence, they are both expensive and require trained medical professionals. The methods also do not involve palpation, a key element in CBE. This research aims in developing a portable and inexpensive automated palpable system that mimics CBE to quantitatively image breast lumps. The method uses a piezoresistive sensor equipped probe consisting of an electronic circuit for collecting deformation-induced electrical signals. The piezoresistive sensor is made by spraying microwave exfoliated graphite/latex blend on a latex sheet. Lumps can be detected by monitoring a change in electrical resistance caused by the deformation of the sensor which is induced by abnormalities in the breast tissue. The electrical signals are collected using a microcontroller and a pixelated image of the breast can be reconstructed. The research is still in progress, and this report serves as proof of concept testing by pressing the probe with hand pressure and reconstructing the electrical signals using Microsoft Excel. Four maps were created for qualitatively analyzing the result. The pressure maps clearly display areas where pressure was applied, indicating the potential of the probe in detecting breast tissue abnormalities. The pressure maps show the feasibility for using such a sensor for the application in CBE. Furthermore, a sensor such as this is also possible of detecting the depth and size of masses within breast tissue, which, may lead to a more accurate diagnosis. Better manufacturing, accuracy, precision, and realtime data feeds are areas of future consideration for this project. This project involves knowledge and applications from mechanical, electrical, computational, and materials engineering.
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