Дисертації з теми "GWO"
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Biscaro, Michele <1996>. "Analisi Tecnica: ottimizzazione di un Trading System tramite PSO e GWO." Master's Degree Thesis, Università Ca' Foscari Venezia, 2022. http://hdl.handle.net/10579/21544.
Повний текст джерелаChan, Yick Mei Keriner. "The functions and occurrence patterns of aspect markers jo, gwo, gan, jyuh in Cantonese narrative discourse." HKBU Institutional Repository, 1999. http://repository.hkbu.edu.hk/etd_ra/401.
Повний текст джерелаAlatram, Ala'a A. M. "A forensic framework for detecting denial-of-service attacks in IoT networks using the MQTT protocol." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2022. https://ro.ecu.edu.au/theses/2561.
Повний текст джерелаBaldaccini, Chiara <1989>. "”Gao Jianli”, dramma storico “minore” di Guo Moruo: traduzione e commento." Master's Degree Thesis, Università Ca' Foscari Venezia, 2014. http://hdl.handle.net/10579/4568.
Повний текст джерелаKirchhain, Simone. "Die Anwendung der Vertikal-GVO auf innerstaatliche Wettbewerbsbeschränkungen nach der 7. GWB-Novelle." Frankfurt,M. Berlin Bern Bruxelles New York, NY Oxford Wien Lang, 2006. http://d-nb.info/98596135X/04.
Повний текст джерелаGuo, Gao [Verfasser], K. D. [Gutachter] Wolff, M. [Gutachter] Farmand, and M. [Gutachter] Klein. "Retrospektive Untersuchung zu implantatverankerten Ohrepithesen / Gao Guo ; Gutachter: K. D. Wolff, M. Farmand, M. Klein." Berlin : Humboldt-Universität zu Berlin, 2005. http://d-nb.info/1207657913/34.
Повний текст джерелаZheng, Ruiqin. "Chong gao yu tui fei : Wang Guowei, Lu Xun, Guo Moruo yu Yu Dafu = Sublime and decadence : Wang Guowei, Lu Xun, Guo Moruo and Yu Dafu /." click here to view the abstract and table of contents click here to view the fulltext, 2005. http://net3.hkbu.edu.hk/~libres/cgi-bin/thesisab.pl?pdf=b18843451a.pdf.
Повний текст джерелаGuo, Gao [Verfasser]. "Fibrillin-1 and elastin fragmentation in the pathogenesis of thoracic aortic aneurysm in Marfan syndrome / Gao Guo." Berlin : Freie Universität Berlin, 2011. http://d-nb.info/1026265851/34.
Повний текст джерелаPrudhomme, Jorian. "Phlébotomes et écosystèmes : impact des facteurs biotiques et abiotiques sur la structure génétique et phénotypique des populations." Thesis, Montpellier, 2015. http://www.theses.fr/2015MONTS027/document.
Повний текст джерелаSandflies are hematophagous insects belonging to the family Psychodidae and the subfamily phlebotominae. This diptera, yellowish, relatively small (2-3 mm) has about 800 species. 70 of these species have been identified as potential vectors of which forty are proven ones. They can transmit different pathogens; the main ones are Leishmania and phlebovirus.This thesis focused on sandflies, vectors of leishmaniasis. Leishmaniases are parasitic diseases caused by protozoa of the genus Leishmania. They affect a wide range of vertebrate hosts, including humans and dogs. They are still a major problem of public health in many countries and are currently in expansion. Although this disease is widely studied, we still have a lot to learn about its vector: the sandfly. For example, the organization of populations in ecosystems and the parameters which structure them are very little studied up to now. It is therefore essential to know the biology of the different actors of a parasite cycle to better understand the transmission of pathogens, to assess risks of transmission, and finally to be able to effectively fight against the disease.In this context, the aim of this thesis is to study the ecology and the structuring of sandfly populations in a known endemic area of leishmaniasis and the impact of biotic and abiotic factors on their organization. To reach this objective, we performed captures of sandflies along a 14km transect located in the Montpellier region which presents an altitudinal, climate and environmental diversity. Sandfly populations have been characterized by taxonomic, spatio-temporal, genetic (microsatellites) and morphometric (geometry morphometry) approaches. The genetic, morphometric and species distribution results were then confronted with climatic (temperature, relative humidity) or environmental parameters (altitude, slope, station, microhabitat).During this work, four species were captured: Phlebotomus ariasi (93.23%), P. perniciosus (0.48%), P. mascittii (0.11%) and S. minuta (6.18%). They have a seasonal activity from May to October with an abundance peak in July-August when average temperatures are optimal for sandflies (20-30°C). Although the environment has been considerably transformed in our study area in 30 years, the abundance of sandflies does not seem to have changed significantly, highlighting their ability to adapt to ecosystem modifications in short and long-term. The presence and abundance of the two predominant species (P. ariasi and S. minuta) are significantly influenced by altitude, temperature, relative humidity, slope and wall orientation.The genetic analyses show that diversity is maintained at all scales of study and that sandflies are organized in micropopulations. The morphometric geometry data reveal a sexual dimorphism, well known in insects but also a phenotypic structuring correlated to environmental or temporal factors (month, slope, altitude and station).Both of these approaches, because of their complementarity, help provide information on the ecology and organization of sandfly populations and to discuss about the consequences in terms of leishmaniasis transmission
Gabriele, Marzia. "La circolazione delle ceramiche del Neolitico nel medio e alto Tirreno e nell’area ligure-provenzale : Studi di provenienza." Thesis, Nice, 2014. http://www.theses.fr/2014NICE2052.
Повний текст джерелаIntense seafaring and cultural/commercial exchanges took place in the region among the Central-Northern Tyrrhenian sea, Liguria and Provence during the VI millennium BCE; these contributed to the neolithisation of the western Mediterranean and were intimately linked to the exploitation and circulation of raw materials, such as obsidian, chert and greenstone. Within this framework, the assessment of ceramic circulation paths is obviously central to understand the economic and cultural relations between different Neolithic groups.Exchanges and potential interactions between different groups were assessed by characterising raw materials used in pottery production, as well as their provenance and diffusion, in order to contribute to research on the early Neolithic in the above mentioned areas.The methodology was aimed at sourcing raw materials and defining technical choices in pottery production by petrographic analyses (stereo- and / or optical microscope) of ceramic samples from some key sites of the Impressa-Cardiale Ware techno-complex, and on their comparison with geo-resources and archaeological pottery data.Pottery production and circulation among the Tyrrhenian, Liguria and Provence areas, in distinct chrono-cultural stages of Early Neolithic, was defined upon the results of these analyses
Tegström, Isabel. "Geo treetrunks." Thesis, Konstfack, Keramik & Glas, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-7952.
Повний текст джерелаKim, Nam-Hui. "Die koreanischen neuen Religionen im Kontext der Religionsgeschichte Koreas : dargestellt und analysiert am Beispiel der wichtigsten vier neuen Religionen, Chondo-gyo, Chungsan-gyo, Taejong-gyo und Wonbul-gyo /." Frankfurt am Main : P. Lang, 2006. http://catalogue.bnf.fr/ark:/12148/cb401822726.
Повний текст джерелаNeto, João. "Geo-Replicated Buckets : An Optrimistic Geo-Replicated Shim for Key-Value Store." Thesis, KTH, Skolan för informations- och kommunikationsteknik (ICT), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-187449.
Повний текст джерелаNordberg, Andreas, and Jonathan Sjölund. "Geo-based media player : An interactive interface for geo-based video streaming." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-129609.
Повний текст джерелаLian, Zhenbiao. "Guo Pu yan jiu." Shanghai : Shanghai san lian shu dian, 2002. http://books.google.com/books?id=q2oyAAAAMAAJ.
Повний текст джерелаBuganauskaitė, Ineta. "Drabužių kolekcija "SOS! GMO!"." Bachelor's thesis, Lithuanian Academic Libraries Network (LABT), 2010. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2010~D_20100903_124056-32955.
Повний текст джерелаBachelor work “SOS! GMO!” reflects nowadays realities addressing the public about the important issue of genetically modified organisms on the flora and fauna. The development of genetically modified organisms in the world is analized in the first section and also the positive and negative aspects of GMO`s are examined. Moreover, scientists opinion on the risk of GM products not only for insects but for mammalian health is represented. According to studies conducted in animals, it is envisaged that future generations can degrade and become infertile. Created works of various artists are dealt in the second section where ecosystem problems are reflexed. The visual sculptures, ceramics, graphics, furniture design, montages, land art, clothing design examples illustrating the authors` position on this issue are introduced. The third section justified the idea of clothing collection. The visual artistic designs, technological samples, drawings are given. Furthermore, the collection of photo sessions and flatbed photo are fulfilled. The fourth chapter deals with outlets of the created clothing collection and also an estimate of the collection provided. The clothes are not planed to sell in a short time due to the fact that it is intended to accession the collection and participate in fashion events. It helps to glorify the name of the designer. The cost of implemental models is 866,79 Lt, sale price - 948,41 Lt, expected profit - 82 Lt. The analysis of information helped to... [to full text]
Knight, James 1979. "Parameterized types for GOO." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/29657.
Повний текст джерелаIncludes bibliographical references (p. 65-66).
An often-useful addition to many programming languages is a generic type or parameterized type system. I have added support for a parameterized type system to the programming language "GOO". Besides the standard functionality, I have allowed the programmer to express some unique relationships between parameterized types that are generally inexpressible in a standard type system, in order to make the system applicable to a wider variety of situations. I have also added a unification system to the method dispatch in GOO in order to allow the relationship between the types of multiple arguments in a method signature to be expressed.
by James Knight.
M.Eng.
Marques, João Miguel Resende. ""GWB" simulation software development." Master's thesis, Universidade de Aveiro, 2009. http://hdl.handle.net/10773/1768.
Повний текст джерелаNas últimas décadas, a evolução da indústria alcançou uma extrema importância na nossa vida pessoal e também no comportamento empresarial. O conjunto de ferramentas existentes nos computadores representam um papel fundamental na comunicação, nas estratégias, nas decisões, nos sistemas de análise de processos das nossas empresas, entre outras. Os software são normalmente concebidos para permitir aos os seres humanos realizar tarefas para as quais o cérebro humano não é capaz, tais como: manipulação de grandes quantidades de informação, realização de cálculos complexos, e controlar simultâneamente muitos processos. Este projecto final foi desenvolvido exactamente sobre a disciplina de software. O presente documento mostra como uma empresa multinacional desenvolve internamente um novo software modular. Algumas técnicas serão investigadas e aplicadas a um problema real existente na empresa Robert Bosch-Bélgica, pertencente ao sector automóvel e principal responsável mundial pela produção de limpa pará-vidros. Aqui se encontrará uma sugestão para uma metodologia do ciclo de vida de um software e será explicado passo a passo todos os aspectos deste processo, desde a criação até ao desenvolvimento desta nova ferramenta de cálculo de apoio à decisão para o design. Esta metodologia foi aplicada à empresa permitindo assim a criação de um manual para o software de simulação chamado “GWB”. Mais precisamente, este projecto descreve a fase de testes, definido como a validação. Esta fase inclui um planeamento e execução de testes do software. Estes resultados foram analisados e comparados com as medições reais. Com base em conhecimentos anteriores, foi conseguido melhorar a precisão do software quer em parâmetros de produção quer em parâmetros de comportamento real dos limpa pará-brisas. Com a criação do manual e do melhoramento do software foram alcançados os dois objectivos principais envolvidos neste estágio. Este trabalho contribuiu significativamente para o desenvolvimento do software de simulação da Robert Bosch, no entanto, é sugerido um conjunto de acções futuras. Estas têm como objectivo ajudar no desenvolvimento do “GWB” para uma implementação adequada no processo de produção de limpa pará-brisas. ABSTRACT: In the last decades the evolution of software industry has reached an extreme importance in our personal daily life and also in the companies behavior. The existing sets of tools represent a vital role in our company’s communications, strategies, decisions supports, systems and process analysis, among others. Software is typically designed to enable humans to perform tasks which the human brain is not well capable, such as: handling large amounts of information, performing complex calculations, and controlling many simultaneous processes. This final project was developed based under the subject software. The present document shows how a multinational enterprise develops internally a new modulate software. Some techniques will be investigated and applied to a real life problem existing in the successful Robert Bosch-Belgium company at the automobile industry world responsible for the production of wiper blades. Here you will find a suggestion of a software life cycle methodology and an explanation step by step of all the aspects of this process from the creation to the development of a new calculation tool for design decision support. This methodology was applied to the company thus enabling to create a handbook for the simulation software called “GWB”. More precisely this project describes the testing phase, defined as validation. This phase contains the planning and execution of software tests. These results were analyzed and compared with real measurements. Based on previous knowledge, was able to improve the accuracy of the software either in production parameters or on parameters of actual behavior. With the creation of the manual and the software improvement two main objectives involved in this internship were accomplished. This work contributed significantly to the development of the Robert Bosch simulation software. However, it is suggested several future actions. To assist in the development of the “GWB” tool for a proper implementation in the wiper blade production process.
Hägglund, Andreas. "Geo-process lookup management." Thesis, Luleå tekniska universitet, Datavetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-60405.
Повний текст джерелаÅsén, Anna. "Den samhälleliga konstruktionen av GMO : Är GMO risk eller möjlighet i arbetet mot hunger?" Thesis, Uppsala universitet, Sociologiska institutionen, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173415.
Повний текст джерелаStephens, Monica. "From Geo-Social to Geo-Local: The Flows and Biases of Volunteered Geographic Information." Diss., The University of Arizona, 2012. http://hdl.handle.net/10150/242399.
Повний текст джерелаTao, Thanh Vinh. "Ensuring availability and managing consistency in geo-replicated file systems." Thesis, Paris 6, 2017. http://www.theses.fr/2017PA066521/document.
Повний текст джерелаGeo-distributed file systems suffer from high latency and network partitions. Because of this, and to ensure high availability, such systems typically commit updates locally, with no latency, and propagate them in the background. Such optimistic replication faces two major challenges: (i) detecting conflicts between concurrent updates and resolving them in a way meaningful for users, while maintaining system integrity invariants; and (ii) supporting legacy applications that are not prepared to deal with concurrency anomalies. Existing optimistic geo-distributed file systems fall short of addressing the challenges. For instance, Dropbox does not support hard links; Andrew File System fails on some concurrent renaming of directories; and all existing systems use automatic conflict resolution that violates the legacy POSIX semantics. We present our solution to the above problems in the design and implementation of a prototype geo-distributed file system, named Tofu. Its design includes a new session abstraction to support the legacy API, while allowing optimistic updates. Unlike previous approaches, our solution is based on a formal model covering all aspects of a Unix-like file system, including directories, inodes, hard links, etc. It is able to detect all conflicts on those data structures, and resolves them in a way that we believe users will find generally reasonable. Experiments show that Tofu is highly scalable, and incurs linear overhead, improving over existing academic and industrial systems
Shi, Zhongyi. "Etude sur l'occidentalisme romantique de Guo Moruo, un poète chinois contemporain /." Berne ; Berlin ; Paris [etc.] : P. Lang, 1993. http://catalogue.bnf.fr/ark:/12148/cb37666919z.
Повний текст джерелаMantani, Andrea. "ArtMap geo-social street art." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2016.
Знайти повний текст джерелаMasso, Marius. "Herausforderungen der glo-kalen Markenführung." St. Gallen, 2008. http://www.biblio.unisg.ch/org/biblio/edoc.nsf/wwwDisplayIdentifier/01652353002/$FILE/01652353002.pdf.
Повний текст джерелаRother, Thomas. "Geometric modelling of geo-systems /." Hannover : Inst. für Strömungsmechanik und Elektronisches Rechnen im Bauwesen, 2001. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=010376760&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Повний текст джерелаCarrillo, Agirre Amaia. "Time Tracking System with GWT." Thesis, Linnaeus University, School of Computer Science, Physics and Mathematics, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-7105.
Повний текст джерелаApplied Research in System Analysis (ARiSA) AB, is a company whose main objective is to market the VizzAnalyzer™ software quality tool and related services, experiences, and research results.
In the beginning, recording the time spent on different activities and projects for project control, cost calculation, and customer billing manually and individually was sufficient and effective. With the number of projects and people involved at a time increasing the existing mechanisms were not sufficient anymore and needed to be replaced to support an efficient recording of time and report generation.
To solve this situation, a prototype of a web-based time tracking system was implemented. The task for this thesis was to build on the existing prototype implementation, to improve and complete it. In detail, to extend the functionalities of the web application adding user, project and activity management, and report creation.
The solution supports an efficient time tracking for employees and it makes the report generation easier.
This thesis describes the requirements for the project and the resulting implementation.
Sundin, Charlotta. "Risker med GMO i jordbruket." Thesis, Södertörn University College, School of Life Sciences, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-2934.
Повний текст джерелаThe world is growing more and more genetically modified (or engineered) crops (GM crops). In Argentina farmers grow almost only GM soy, and no conventional soy. It is a controversial subject, since genetic engineering has many advocates and critics. The positive sides of GM crops are that it can create higher yields and incomes for the farmers. Those are the main objects of growing GM crops. Critics, on the other hand, say that GM crops have bad effects on the environment, and the risks could be too high. For example GM crops can spread to neighboring farms, where organic crops are growing. Many scientists claim that nobody really have enough knowledge of the effects of growing GM crops, and therefore thorough risk assessments are needed to examine the effects and possible risks of growing GM crops before starting to grow them. Politicians, too often, make decisions on false scientific grounds, when they claim that genetic engineering is a safe and precise method. The large corporations developing GMOs are heavily influencing political decision making. Scientists have studied the genetic engineering process and the results show that the method is not precise. It is difficult to know exactly what gene is transferred, and where it ends up. It is also important to discuss the precautionary principle in the decision making process.
Kallbach, Maria. "Orchestrierung von Geo Web Services." Master's thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2010. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-25142.
Повний текст джерелаStumm, Andreas, and Norbert Pfurr. "Klassifikationen, Konkordanzen & GEO-LEO." Universitätsbibliothek Chemnitz, 2005. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200500697.
Повний текст джерелаStumm, Andreas, and Norbert Pfurr. "Klassifikationen, Konkordanzen & GEO-LEO." Universitätsbibliothek Chemnitz, 2007. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200701317.
Повний текст джерелаJarahnejad, Mariam. "New Low GWP Synthetic Refrigerants." Thesis, KTH, Tillämpad termodynamik och kylteknik, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-96118.
Повний текст джерелаKappes, Daniel. "Nebenbestimmungen im Fusionskontrollrecht des GWB /." Berlin : TENEA Verl. für Medien, 2002. http://www.gbv.de/dms/ilmenau/toc/364681349.PDF.
Повний текст джерелаNašlėnė, Žilvinė. "Farmacininkų požiūrio į GMO vertinimas." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2010~D_20140625_190108-18890.
Повний текст джерелаThe aim of this study was to assess the approach to GMO’s of drugstore’s worker’s. In order to realize the overall aim, three goals were established: to assess the knowledge of drugstore’s worker’s about GMO; to assess the drugstore’s worker’s approach to GMO risk to the environment and human health; to compare the results with the study of “Spinter” where was evaluated publics approach to GMO’s 2009. Methods. Drugstore’s workers were interviewed by anonymous questionnaire. 150 respondents were interviewed in total: 75 from Vilnius and 75 from Ukmergė and Šakiai. The results were processed using the statistical package SPSS/w 15 and traditional statistic methods. Results. Exploring the drugstore’s worker’s opinion about GMO, there was found that the opinion about GMO was negative of 67,3% of respondents. 14% of respondents knew about GMO and GMP enough, 60% of respondents knew about GMO just a little, but wanted to get more information. 46% of respondents thought that live stocks are foddering with GM fodders which are made abroad. 41% of respondents thought that live stocks are foddering with GM fodders which are made from cultures witch were grown in Lithuania. Most of respondents – 64,7% assumed that they would like to have a right to choose while buying and using GMO. 58% of respondents wouldn’t want to use GM food, 48,7% of respondents – would use GM food only if they had the evidences that GMO is no harmful. Most of drugstores’ workers suggested that food additives... [to full text]
Dumville, Mark. "Geo-referencing : Earth Observation imagery." Thesis, University of Nottingham, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.282598.
Повний текст джерелаReis, Matheus. "A natureza como cont?gio." Pontif?cia Universidade Cat?lica de Campinas, 2017. http://tede.bibliotecadigital.puc-campinas.edu.br:8080/jspui/handle/tede/1044.
Повний текст джерелаMade available in DSpace on 2018-03-22T13:48:11Z (GMT). No. of bitstreams: 1 MATHEUS REIS.pdf: 9573689 bytes, checksum: 131ba12f90e28aafb67423d293a83aa8 (MD5) Previous issue date: 2017-12-14
With the intensive consumption of natural resources that we have achieved in the 21st century and the recognition of human actions as drivers of socio-environmental exhaustion, it is imperative to investigate ways of interfering in the environments through interaction and transforming these relationships into potentiality. Through this, we search through cartography a relational enunciation approaching of artistic processes and eco-logical practices developed in the Atelier Contagio. From this mapping, are presented fascicles that contribute with a theoretical / conceptual effort to approach some senses present in these practices.
Com o consumo intensivo dos recursos naturais que alcan?amos no s?culo XXI e o reconhecimento das a??es humanas como condutoras do esgotamento socioambiental, ? imprescind?vel investigar modos de interfer?ncia nos ambientes por meio da intera??o e de transformar essas rela??es em pot?ncia. Com isso, busca-se atrav?s da cartogr?fia uma enuncia??o relacional aproximando processos art?sticos e pr?ticas eco-l?gicas desenvolvidas no Atelier Cont?gio. A partir desse mapeamento, apresentam-se fasc?culos que contribuem com um esfor?o te?rico/conceitual para abordar alguns sentidos presentes nessas pr?ticas.
Kallbach, Maria. "Orchestrierung von Geo Web Services." Master's thesis, Hochschule für Technik und Wirtschaft Dresden, 2009. https://slub.qucosa.de/id/qucosa%3A634.
Повний текст джерелаVyletová, Veronika. "Pravomoc Evropské unie regulovat GMO." Master's thesis, Vysoká škola ekonomická v Praze, 2015. http://www.nusl.cz/ntk/nusl-204069.
Повний текст джерелаGianessi, Davide. "Applicazione smartphone geo-social game." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/4555/.
Повний текст джерелаLucchi, Casadei Nicola. "Applicazione Smartphone Geo-Social Game." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/4565/.
Повний текст джерелаPublishing, Government. "GPO Access: General Searching Instructions." U.S Government Printing Office, 2003. http://hdl.handle.net/10150/105921.
Повний текст джерелаBack, Sara. "Autoscaling in geo-distributed clouds." Thesis, Uppsala universitet, Institutionen för informationsteknologi, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-391931.
Повний текст джерелаBergo, Anna <1997>. "I Big Data nella GDO." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19850.
Повний текст джерелаAndrade, Chang Melissa, and Rivera Regina Soriano. "Pokemon Go: ¿”Go” o no “Go”?" InnovaG, 2017. http://repositorio.pucp.edu.pe/index/handle/123456789/131504.
Повний текст джерелаHsu, Yuk-kwan. "Reading male and nation trouble in Yu Dafu (Yu Dafu) and Guo Moruo (Guo Moruo)." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B37087198.
Повний текст джерелаDias, Roberto Alexandre dos Santos. "Characterization of Gαo role on neuritogenesis: a focus on the Gαo-Amyloid precursor protein complex". Doctoral thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22057.
Повний текст джерелаGαo is the most abundant Gα subunit present in the brain, however, its specific functions are still far from clear. Studies of the signaling pathways modulated by Gαo have uncovered potential roles for Gαo in the development of the nervous system, especially in neuritogenesis. The characterization of Gαo interactome has also been crucial for the better understanding of this protein’s functions. One of the Gαo interacting proteins is the amyloid precursor protein (APP), a protein that is involved in several physiological functions, such as cell survival, neuronal migration, and neuronal differentiation. APP is also best known for its involvement in Alzheimer’s Disease (AD). APP binds and activates Gαo, an interplay that was associated with neuronal migration and AD. However, so far, no published study has investigated the effects of the APP-Gαo interaction on neuritogenesis. The main goal of this work was thus to characterize Gαo role on neuritogenesis by focusing the research on the neuritogenic effects of the Gαo-APP complex. First, by using SH-SY5Y neuroblastoma cells, we studied the impact of APP serine 655 (S655) phosphorylation on the APP-Gαo interaction. Through the use of two APP mutants mimicking the phosphorylated and dephosphorylated state of S655, SE and SA APP respectively, we have demonstrated that S655 phosphorylation increases APP efficiency to bind and activate Gαo. Moreover, we present evidence that APP modulates Gαo neuritogenic effects in a phosphodependent mechanism. STAT3 and ERK1/2 signaling displayed a sequential activation on this neuritogenic mechanism, with STAT3 being mainly involved in the formation of new processes, while ERK1/2 was more involved in neuritic elongation. We also present data supporting a role for the APP-Gαo complex on dendritogenesis in rat primary neuronal cultures. The second part of this work focused on unraveling the mechanisms involved in the control of APP and Gαo cellular protein levels. We identified the lysosome as a new pathway by which Gαo is degraded, as an effect of SA APP overexpression. We also provide evidence that this degradation mechanism might be part of chaperone-mediated autophagy, through which APP-Gαo signaling might be regulated. Finally, due to our interest in studying neuronal differentiation and a lack of reliable tools to analyze phase contrast images, we developed NeuronRead, an ImageJ macro capable of semi-automated analysis of both phase contrast and fluorescence neuronal images. NeuronRead was extensively validated and used to monitor SH-SY5Y differentiation upon modulation of Gαo activity. With this work, we delivered new data that advances knowledge on the function and regulation of the Gαo-APP complex in a neuronal context, and provided the scientific community with a new tool for the study of neuronal differentiation.
Gαo é a subunidade Gα mais abundante no cérebro, no entanto, as suas funções especificas ainda estão longe de serem claras. Estudos das vias de sinalização moduladas pela Gαo têm exposto potenciais papéis para a Gαo no desenvolvimento do sistema nervoso, especialmente em neuritogénese. A caracterização do interactoma da Gαo também tem sido crucial para uma melhor compreensão das funções desta proteína. Uma das proteínas interatoras da Gαo é a proteina precursora de amiloide (APP), uma proteina que se encontra envolvida em várias funções fisiológicas, como sobrevivência celular, migração neuronal, e diferenciação neuronal. APP também é mais conhecida pelo seu envolvimento da Doença de Alzheimer (AD). APP liga-se e ativa a Gαo, uma interação que tem sido associada com migração neuronal e AD. No entanto, até agora, não existem estudos publicados que investiguem a interação APP-Gαo na neuritogénese. O principal objetivo deste trabalho foi então caracterizar o papel da Gαo na neuritogénese através do foco na investigação dos efeitos neuritogénico do complexo Gαo-APP. Primeiro, através do uso de células de neuroblastoma SH-SY5Y, estudámos o impacto da fosforilação da serina 655 (S655) da APP na interação APP-Gαo. Através do uso de dois mutantes da APP que mimetizam o estado fosforilado e desfosforilado da S655, SE e SA APP respetivamente, demonstrámos que a fosforilação da S655 aumenta a eficiência da APP em ligar e ativar a Gαo. Além disso, apresentamos provas de que a APP modula os efeitos neuritogénicos da Gαo num mecanismo fosfo-dependente. Neste mecanismo neuritogénico, a sinalização da STAT3 e ERK1/2 exibiram uma ativação sequencial, com a STAT3 participando na formação de novos processos e a ERK1/2 na elongação dos mesmos. Apresentamos ainda dados que suportam um papel da APP-Gαo na dendritogénese em culturas neuronais primárias. A segunda parte deste trabalho focou-se na investigação de mecanismos envolvidos no controlo dos níveis proteicos celulares da APP e Gαo. Identificámos o lisossoma como um novo processo pelo qual a Gαo é degradada em consequência da sobre expressão da SA APP. Também mostramos provas de que este mecanismo pode fazer parte de autofagia mediada por chaperonas, através do qual a sinalização da APP-Gαo poderá estar a ser regulada. Finalmente, devido ao nosso interesse em estudar diferenciação neuronal e à falta de ferramentas para este estudo em imagens de contraste de fase, criámos o NeuronRead, uma macro do ImageJ capaz de analisar de forma semiautomática imagens neuronais de contraste de fase e fluorescência. NeuronRead foi extensivamente validado, e usado para monitorizar a diferenciação de células SH-SY5Y após modulação da atividade da Gαo. Com este trabalho contribuímos com novos dados que ajudam na compreensão da função e regulação do complexo Gαo-APP, e disponibilizamos para a comunidade cientifica uma nova ferramenta para o estudo da diferenciação neuronal
Crnkovich, Erin. "GMO: Friend or Foe? An Analysis of the GMO Debate with Special Focus on India." Thesis, University of Oregon, 2018. http://hdl.handle.net/1794/23921.
Повний текст джерелаCao, Z. "Improving the accuracy and the efficiency of geo-processing through a combinative geo-computation approach." Thesis, University College London (University of London), 2016. http://discovery.ucl.ac.uk/1474521/.
Повний текст джерелаPetruškevičiūtė, Erika. "Genetiškai modifikuotų organizmų gamybos ir naudojimo teisinis reguliavimas bei įtaka aplinkai ir visuomenei." Master's thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140603_111446-84625.
Повний текст джерелаThe Master’s final paper on GMO discovered that the majority of respondents have no strong opinion about production and use of GMO, but one third of responses on production and use of GMO were negative. Many people consider that GMO not only negatively affect human health, but also damage environment. Moreover, eating genetically-modified food can irreversibly change human’s genetic code as well as irreversible mutations in plants’ and animals’ populations. However, some people tend to use GM foods because they are cheaper and can be stored longer than other foods. Even though some of the respondents see benefits of GMO production and usage, almost all of the respondents claim that genetically engineered products interest mostly large companies that are seeking to profit from GMO. The most obvious finding to emerge from this study is that people learn about GMO from mass media and communicating with friends and relatives mostly, but they also admit the lack of credible information on GMO. More than a half of the respondents would like to receive more information about genetically modified organisms.
Schiefer, Christian, Rolf Schubert, Birgit Pölitz, Angela Kühne, Karsten Westphal, Olaf Steinhöfel, and Annette Schaerff. "Untersuchungen zum Anbau von GVO in Sachsen - Untersuchungen zu Konsequenzen des Anbaus von GVO in Sachsen." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2008. http://nbn-resolving.de/urn:nbn:de:bsz:14-ds-1215501771245-31406.
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