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Статті в журналах з теми "Grippe équine":
Adeyefa, C. A. O., C. Hamblin, A. A. Cullinane, and J. W. McCauley. "Enquête sérologique de la grippe équine sur le territoire du Nigeria." Revue d’élevage et de médecine vétérinaire des pays tropicaux 49, no. 1 (January 1, 1996): 24–27. http://dx.doi.org/10.19182/remvt.9540.
Sidibé, Souleymane, Z. Bocoum, C. F. Simbé, K. Tounkara, Mohamed, Mostafa Bakkali, and M. Kané. "Grippe équine au Mali : résultats d’une enquête séroépidémiologique." Revue d’élevage et de médecine vétérinaire des pays tropicaux 55, no. 2 (February 1, 2002): 89. http://dx.doi.org/10.19182/remvt.9837.
Boussetta, M., A. Chabchoub, Abdeljelil Ghram, I. Jomaa, A. Ghorbel, T. Aouina, and H. Ben Amor. "Enquête séroépidémiologique sur la grippe et l'anémie infectieuse des équidés dans le nord-est tunisien." Revue d’élevage et de médecine vétérinaire des pays tropicaux 47, no. 3 (March 1, 1994): 277–81. http://dx.doi.org/10.19182/remvt.9086.
MINKE, Jules Maarten, and Michel BUBLOT. "La grippe équine : une mise à jour." Bulletin de l'Académie vétérinaire de France, no. 1 (2004): 43. http://dx.doi.org/10.4267/2042/47737.
Tanya, V. N., and G. R. Scott. "Hémagglutination virale des globules rouges de mouton stabilités par la glutaraldéhyde." Revue d’élevage et de médecine vétérinaire des pays tropicaux 47, no. 3 (March 1, 1994): 283–84. http://dx.doi.org/10.19182/remvt.9087.
Adam-Poupart, Ariane, Laurie-Maude Drapeau, Sadjia Bekal, Geneviève Germain, Alejandra Irace-Cima, Marie-Pascale Sassine, Audrey Simon, Julio Soto, Karine Thivierge, and France Tissot. "Professions à risque pour l’acquisition des zoonoses d’importance pour la santé publique au Québec." Relevé des maladies transmissibles au Canada 47, no. 1 (January 29, 2021): 56–67. http://dx.doi.org/10.14745/ccdr.v47i01a08f.
Dubouloz, Sandra, Cédric Favre, and Catherine Thévenard-Puthod. "La maturité équirepreneuriale : d’un facteur clé de succès de la reprise d’entreprise en SCOP à un outil actionnable." Entreprendre & Innover 57, no. 4 (December 1, 2023): 8–21. http://dx.doi.org/10.3917/entin.057.0008.
Pacault, M., M. Prizzi, M. Veteau, and E. Garcia Munne. "Équipe mobile de vaccination Grippe intra CHU." Médecine et Maladies Infectieuses 49, no. 4 (June 2019): S164—S165. http://dx.doi.org/10.1016/j.medmal.2019.04.019.
Lefebvre, Sonia, and Colette Deaudelin. "Les interactions et la performance à l’écrit d’élèves du primaire dans une situation d’apprentissage avec les pairs soutenu par ordinateur." Articles 27, no. 3 (February 7, 2005): 621–48. http://dx.doi.org/10.7202/009967ar.
MAZALOVIC, K. "Interprofessionnalité en santé : mythe ou réalité ?" EXERCER 31, no. 165 (September 1, 2020): 291. http://dx.doi.org/10.56746/exercer.2020.165.291.
Дисертації з теми "Grippe équine":
Fougerolle, Stéphanie. "La grippe équine : détection moléculaire et caractérisation des souches de virus influenza : caractérisation de la réponse immunitaire après vaccination." Caen, 2016. http://www.theses.fr/2016CAEN2067.
The equine influenza virus (EIV) belongs to the family Orthomyxoviridae and is one of the most important equine respiratory pathogens, especially due to the economic losses associated with outbreaks. In horses, infection with the influenza virus causes significant morbidity. Mortality is uncommon and mostly associated with complications, such as secondary bacterial infections. Although there are vaccines since the 60’s, outbreaks, caused by the H3N8 subtype, are recorded around the world, including Sweden, Japan, Australia and France. Among the current issues related to EIV, this thesis focuses on both the pathogen and the host. , The molecular diversity of EIV strains and a possible link with virulence was investigated. This work involved a monitoring of EIV strains circulating in France and brought new notions about virulence mechanisms. The problem of low responder is a phenomenon accepted but not well understood in horses. The second aspect of this thesis was to study sub-optimal response to immunisation observed in some horses. The humoral immune response monitored, through the performance of SRH tests, in 202 foals during the primary course of vaccination against equine influenza. Results allowed to define the frequency of individuals that did not develop an adequate immune response and to highlight two independent factors playing a major role in the establishment of this sub-optimal response: the age of the foal and the presence of maternal antibodies at the time of first immunisation. In a preliminary study, evaluation of mRNA cytokines expression levels induced after EI immunization did not allow identification of intrinsic factors associated with low vaccination response
Carnet, Flora. "Amélioration des protocoles vaccinaux contre la grippe équine et la rhinopneumonie : apport de l’iPPVO en tant qu’adjuvant dans le modèle équin, nouvelle approche de la mesure des anticorps neutralisants." Electronic Thesis or Diss., Normandie, 2023. http://www.theses.fr/2023NORMC413.
Equine influenza virus (EIV) and equine herpesvirus-1 (EHV-1) are frequently described in many countries and are two endemic pathogens in the French equine population. These infectious diseases have important consequences both in terms of animal health and welfare and in terms of economic impact. The fight against these viruses is essentially based on the implementation of preventive measures such as vaccination. Despite this epizootics of EIV and EHV-1 are regularly declared in France and throughout the world. Neutralising antibodies, synthesised in response to infection or after immunisation, represent the main line of defence against these viruses. Improved vaccines and a wider range of tools to measure neutralising antibodies can be a valuable strategy in the fight against these viruses. In order to improve the efficacy of the vaccine response, both in magnitude and duration, the use of adjuvants is one way to improve immunogenicity. This thesis consisted, in the first instance, in establishing the proof of concept of the use of iPPVO as an innovative adjuvant in vivo in horses in the context of vaccination against EIV. For this purpose, antibodies were measured by SRH, a method for which the correlates of protection are well defined. The addition of iPPVO at vaccination significantly increased the antibody level to EIV and protection in horses up to 6 months after immunisation. In a second step, a new method for measuring EIV antibodies in serum based on impedancemetry was developed to improve on current methods and facilitate high throughput analysis. This neutralisation test correlated well with SRH test. Another study was performed, which demonstrated the adjuvant potential of iPPVO in horses during vaccination against EHV-1,4. The antibody response measured by serum neutralisation increased up to 5 months after immunisation. Finally, preliminary results on the mechanism of action of iPPVO on peripheral blood mononuclear cells demonstrated the importance of the interferon
Kleij, Lena. "Identification and validation of the virulence determinants of circulating equine influenza viruses." Electronic Thesis or Diss., université Paris-Saclay, 2023. http://www.theses.fr/2023UPASL136.
Influenza viruses are enveloped, their genome being segmented into 8 negative RNA segments. They are classified in the Orthomyxoviridae family. They are the etiological agents of the flu, a respiratory disease that affects many mammalian and avian species. Equine influenza is caused by the H3N8 and H7N7 subtypes of the type A influenza virus, the latter being extinct since the 1970s. Despite the existence of a vaccine, France has experienced several H3N8 epidemics since the 2000s. To reduce the significant economic impact of these epidemics for the equine industry, it is necessary to establish rapid, robust, and on-terrain applicable diagnostic tests to limit the circulation of the virus as much as possible and identify its virulence determinants as well as characterize antigenic drift.We studied the potential of the so-called “long read” sequencing technique developed by Oxford Nanopore Technologies. We carried out a characterization of the complete genome of two equine H3N8 viruses that circulated in France in 2009 and 2018 (A/equine/Paris/1/2018 and A/equine/Beuvron-en-Auge/2/2009, two viruses of clade 1 Florida) as well as the two strains of the vaccine commonly used in France.Our results demonstrated the reliability of this sequencing technique using amplicons of the eight genomic segments of the four viruses analyzed as well as the ability to produce reliable readings from direct sequencing of viral RNA (results presented in the first part). Analysis of the amino acid sequence of hemagglutinin HA of circulating strains demonstrated a very slight antigenic drift compared to vaccine strains with specific substitutions such as T161I in A/equine/Paris/1/2018 and N188T in the post-2015 strains, two substitutions located in the antigenic site B. The antigenic site E also shows modifications in the post-2018 strains, with the N63D substitution.Genomic segment 2 encodes one of the three subunits of the viral RNA polymerase, PB1, as well as an accessory protein, PB1-F2, of an alternative reading frame. PB1-F2 is recognized as a virulence determinant. While the A/equine/Paris/1/2018 strain encodes a variant 90 amino acids long, many strains, including A/equine/Beuvron-en-Auge/2/2009, encode a variant only 81 residues. Biological and biochemical tests were carried out to characterize the properties of each of these two forms of PB1-F2. In an assay where the long form of PB1-F2 is expressed in eukaryotic cells without other viral constituents, it abolishes the membrane potential of the cellular mitochondria. Placed in the presence of synthetic vesicles mimicking the mitochondrial outer membrane, the long form of PB1-F2 permeabilizes them more effectively than the short form. Amino acid sequence analyzes of the viral proteins (mainly HA and PB1-F2) are presented in a second part.In order to validate the impact of PB1-F2 on virulence in an infectious context, we sought to establish a reverse genetics system for the A/equine/Paris/1/2018 virus (third part). To do this, the 8 genomic segments were cloned into the pRF483 plasmid to ensure the synthesis of genomic RNA strands and the expression of viral proteins. The sequence of the inserts of each of the plasmids was validated. To validate the functioning of the replicative complex encoded by 4 of the 8 viral segments cloned in pRF483 (PA, PB1, PB2 and NP), these plasmids were transfected with a plasmid coding for the NA genomic segment in which its reading frame was substituted. by a reporter gene, luciferase. Under these experimental conditions, activity of the RNA-polymerase complex was detected. These tests will be extended for the production of recombinant viruses by transfection of the 8 constructed plasmids
Bui, The Quang. "Criblage virtuel sur grille de composés isolés au Vietnam." Thesis, Clermont-Ferrand 2, 2015. http://www.theses.fr/2015CLF22583/document.
Virtual Screening (VS) is a computational technique used in the drug discovery process to select the most promising candidate drugs for in vitro testing from millions of chemical compounds. This method can offer an efficient alternative to reduce the cost of drug discovery and platform. The Natural Products Chemistry Institute of the Academy of Sciences of Vietnam (INPC) collects samples from local biodiversity and determines the 3D structure of single molecules. Their challenge is to set up a virtual screening platform on grid computing for their chemists to process their data. However, as the number of users who might have a wide range of virtual screening applications (in terms of the number of tasks and execution time) increases with limited available computing resources, it becomes crucial to devise an effective scheduling policy that can ensure a certain degree of fairness, user satisfaction and overall system throughput. In this context, the thesis focuses on an effective scheduling policy for the virtual screening workflow where multiple users with varying numbers of tasks are actively sharing a common system infrastructure. We have researched in theory and proposed some candidate policies. With the simulation results and the experimentation results in real system, we proposed the best policy for the fairness between users, which can be applied to INPC virtual screening platform
Книги з теми "Grippe équine":
Blake, Robert Rogers. Culture d'équipe: La grille des équipes gagnantes. Paris: Éditions d'Organisation, 1988.
ROBERT, Pascal. Temporalités numériques - Tome 1 : La dynamique des technologies de l’information et de la communication (XIX-XXs). Editions des archives contemporaines, 2021. http://dx.doi.org/10.17184/eac.9782813004246.
Частини книг з теми "Grippe équine":
Raymond, Émilie, Christophe Tremblay, and Jean-Guy Lebel. "L’inclusion sociale des personnes aînées : une grille pour favoriser les conditions d’une pleine participation en recherche." In Recherches participatives et équité en santé, 31–50. Les Presses de l’Université de Laval, 2022. http://dx.doi.org/10.1515/9782763758572-006.
Звіти організацій з теми "Grippe équine":
Marchildon, Allison, Steve Jacob, and Aude Marie Marcoux. Grille de réflexivité sur les enjeux éthiques des systèmes d’intelligence artificielle (SIA). Observatoire international sur les impacts sociétaux de l’intelligence artificielle et du numérique, October 2021. http://dx.doi.org/10.61737/oxha5372.