Добірка наукової літератури з теми "Glyde Package"
Оформте джерело за APA, MLA, Chicago, Harvard та іншими стилями
Ознайомтеся зі списками актуальних статей, книг, дисертацій, тез та інших наукових джерел на тему "Glyde Package".
Біля кожної праці в переліку літератури доступна кнопка «Додати до бібліографії». Скористайтеся нею – і ми автоматично оформимо бібліографічне посилання на обрану працю в потрібному вам стилі цитування: APA, MLA, «Гарвард», «Чикаго», «Ванкувер» тощо.
Також ви можете завантажити повний текст наукової публікації у форматі «.pdf» та прочитати онлайн анотацію до роботи, якщо відповідні параметри наявні в метаданих.
Статті в журналах з теми "Glyde Package"
1
Croon, Marcel, Joshua Bluett, Luke Titus, and Raymond Johnson. "Formation evaluation case study: Glyde unconventional Middle Proterozoic play in the McArthur Basin, northern Australia." APPEA Journal 55, no. 2 (2015): 429. http://dx.doi.org/10.1071/aj14064.
Повний текст джерелаАнотація:
The Glyde–1 and Glyde Sidetrack–1 wells were drilled by Armour Energy in the Glyde Sub-basin of the McArthur Basin, NT, Australia in August 2012. This program was to evaluate the unconventional hydrocarbon potential of the Barney Creek Shale source rock and the conventional potential of the Coxco Dolomite of the McArthur Group. The Glyde wells discovered gas in both formations. Transtensional faults in this region allowed to form a series of fault-bounded depocentres. The target gas source of the Glyde discovery is located in 1640 Ma organic-rich black shales of the Barney Creek Formation. Weatherford was contracted to acquire both vertical and lateral advanced log suites and perform subsequent log interpretation to constrain the in situ minimum and maximum horizontal stress regimes to assist with maximising gas production from future lateral placement pilot programs in the Coxco Hydrothermal Dolomite (HTD) Play. Two stratigraphic and structural domains were defined by the observed features in the image log data; a dolostone dominated, fractured strata below an erosional surface. Above this stratigraphic timeline is a monotonous package of laminated, lower-energy Barney Creek Formation sediments. Observed changes in azimuths and dips of the measured beddings suggest a phase of compression after deposition of the Barney Creek Formation, resulting in gentle folding of the formations. The porous gas-charged HTD play is drilled in top of the anticline, which is further characterised by a significant number of conductive fractures, likely indicative of open fractures.
2
Jarrett, Amber J. M., Tim J. Munson, Ben Williams, Adam H. E. Bailey, and Tehani Palu. "Petroleum supersystems in the greater McArthur Basin, Northern Territory, Australia: prospectivity of the world’s oldest stacked systems with emphasis on the McArthur Supersystem." APPEA Journal 62, no. 1 (May 13, 2022): 245–62. http://dx.doi.org/10.1071/aj21018.
Повний текст джерелаАнотація:
This study assesses the prospectivity of the world’s oldest known stacked petroleum systems from the Proterozoic greater McArthur Basin (Northern Territory, Australia), which has immense potential to host both conventional natural gas and oil, in addition to shale-gas accumulations. The Mesoproterozoic succession of the Beetaloo Sub-basin and surrounding region hosts the Territory’s premier shale-gas play and is at an advanced stage of exploration for shale hydrocarbon plays. However, there is also potential for natural gas in older sedimentary packages, with flows and shows reported in underlying Paleoproterozoic successions. At the continent-scale, four regional petroleum supersystems are identified and described in order to provide a platform for consistent nomenclature at the sedimentary package and group level; in ascending stratigraphic order; these are the Paleoproterozoic Redbank and McArthur supersystems, the Paleoproterozoic–Mesoproterozoic Lawn Supersystem, and the Mesoproterozoic Beetaloo Supersystem. The Redbank and Lawn supersystems are newly named and defined, and the Beetaloo Supersystem is renamed from the former Urapungan Supersystem. Eight possible conventional natural gas plays and six shale-gas plays are documented within the McArthur Supersystem, which incorporates Glyde Package successions of the McArthur Basin and the Birrindudu Basin. Petroleum play concepts are also described from this supersystem to assist with assessing the potential for gas resources. A better understanding of the petroleum systems of the greater McArthur Basin is critical to the targeting of areas for geoscience data acquisition in order to facilitate the reduction of exploration search space; and it enables a more rigorous assessment of the potential for conventional and unconventional hydrocarbon resources at local (play) and regional scales.
3
Thambidurai, Yuvarani, Sudarsanam Durairaj, Siddhardha Solosan S, Sewali Ghosh, and Habeeb Shaik Mohideen. "Binding Potential of Dysidea Herbacea Derived Small Molecules to Breast Cancer Implicating Targets Estrogen and Epidermal Growth Factor Receptors." Biomedical and Pharmacology Journal 14, no. 01 (March 28, 2021): 391–402. http://dx.doi.org/10.13005/bpj/2139.
Повний текст джерелаАнотація:
Identifying new targets and new drugs has always been a daunting task, especially in cancer research. This studyexamines the binding interaction and the drug-likeness properties of small molecules derived from marine sponge Dysideaherbacea to breast cancer receptors: epidermal growth factor receptor and estrogen receptor. The receptor’s interaction with the ligand was evaluated using the Schrodinger Glide package, and affinities were assessed based on the glide score. Ligand molecules that have higher binding affinity were evaluated further for their ADMET properties using Molinspiration.We found multiple ligands binding to these targets; however, Pyridine 3 carboxyamidewas found to have binding affinity to both the receptors. Compared to the other small molecules,further simulation studies could be taken up to ascertain its structural dynamics and ensuing in-vitro experiments that could prove growth inhibition of breast cancer cells.
4
Mahendran, Radha. "“Molecular Modeling and Identification of Inhibitors against Human Mitochondrial Thymidine Kinase 2”." Asian Journal of Pharmaceutical and Clinical Research 10, no. 5 (May 1, 2017): 103. http://dx.doi.org/10.22159/ajpcr.2017.v10i5.17185.
Повний текст джерелаАнотація:
Objective:Mitochondrial disorders linked to Thymidine Kinase 2 (TK2) deficiency is associated to long term treatment with antiviral nucleoside analogues such as AZT (AZidoThymidine). The accumulation of AZT-TP (AZidoThymidine-TriPhosphate) is suggested to affect DNA polymerase, resulting in mtDNA (mitochondrial DNA) depletion. Thus a potent and selective inhibitor for TK2 is essential to be predicted.Methods: The human mitochondrial TK2was modeled usingModeller and the structure was evaluated using Ramachandran plot. The ligand molecule of both the derivatives of deoxythymidine and thioureawere optimized usingChemsketch and were further docked using GLIDE Schrödinger package 2009.Results: The docking results of both Deoxythymidine and Thiourea derivatives against the target TK2 were analyzed to find the ligands with good dock score and Glide energy. The ligands were selected and induced fit docking of both the derivatives were carried out and the interactions were observed usingPyMol.Conclusion: The present study indicates that deoxythymidine derivatives interact significantly and hence serve as selective inhibitors against Human Mitochondrial TK2.Keywords: Thymidine kinase 2, Azidothymidine-triPhosphate, Docking, Grid-based ligand docking with energetics, Deoxythymidine, Thiourea
5
J. Prathyusha and C. Asha Deepti. "SYNTHESIS, ANTIMICROBIAL, AND ANTITUBERCULAR ACTIVITIES OF NOVEL N-PYRAZOLYLBENZAMIDE DERIVATIVES." RASAYAN Journal of Chemistry 15, no. 04 (2022): 2407–16. http://dx.doi.org/10.31788/rjc.2022.1547092.
Повний текст джерелаАнотація:
The current study investigated the antimicrobial and antitubercular activities of novel N-Pyrazolyl Benzamide derivatives. The study includes the synthesis, characterization, and ligand-based molecular docking of the designed molecules. Synthesis of N-Pyrazolyl Benzamide derivatives involves a two-step process in which 5-amino pyrazole (3) intermediate is produced by the condensation reaction of aryl hydrazine (1) and β-keto nitrile (2) in acidic conditions. The final N-Pyrazolyl Benzamide derivatives (5a-n) were synthesized by the reaction involving amide coupling between 5-amino pyrazole (3) and various substituted benzoyl halides (4a-n). The compounds (5a-n) were tested for antimicrobial activity against two gram-negative strains (E. coli and S. Typhi), two gram-positive strains (S. aureus and B. subtilis) and M. tuberculosis MTB H37Rv (ATCC 27294) strains were used for evaluating antitubercular activity. Molecular docking studies of designed derivatives were performed with the Schrodinger glide package against mycobacterial pantothenate synthetase (PDB ID: 4MQ6). All the tested compounds displayed moderate to good antimicrobial and antitubercular activity against the selected strains of bacteria. All the docked molecules were found occupying the active site and established a minimum of two hydrogen bond interactions in molecular docking studies
6
Yu, Weihua, Abbas Vosoogh, Bowu Wang, and Zhongxia Simon He. "Substrateless Packaging for a D-Band MMIC Based on a Waveguide with a Glide-Symmetric EBG Hole Configuration." Sensors 22, no. 17 (September 4, 2022): 6696. http://dx.doi.org/10.3390/s22176696.
Повний текст джерелаАнотація:
This paper presents a novel substrateless packaging solution for the D-band active e mixer MMIC module, using a waveguide line with a glide-symmetric periodic electromagnetic bandgap (EBG) hole configuration. The proposed packaging concept has the benefit of being able to control signal propagation behavior by using a cost-effective EBG hole configuration for millimeter-wave- and terahertz (THz)-frequency-band applications. Moreover, the mixer MMIC is connected to the proposed hollow rectangular waveguide line via a novel wire-bond wideband transition without using any intermediate substrate. A simple periodical nail structure is utilized to suppress the unwanted modes in the transition. Additionally, the presented solution does not impose any limitations on the chip’s dimensions or shape. The packaged mixer module shows a return loss lower than 10 dB for LO (70–85 GHz) and RF (150–170 GHz) ports, achieving a better performance than that of traditional waveguide transitions. The module could be used as a transmitter or receiver, and the conversion loss shows good agreement in multiple samples. The proposed packaging solution has the advantages of satisfactory frequency performance, broadband adaptability, low production costs, and excellent repeatability for millimeter-wave- and THz-band systems, which would facilitate the commercialization of millimeter-wave and THz products.
7
Chopra, Bhawna, Ashwani K. Dhingra, Deo N. Prasad, Sakshi Bhardwaj, and Sonal Dubey. "Synthesis and In Silico Molecular Docking Studies on Substituted Piperic Acid Derivatives as Inhibitors of Bacterial DNA Gyrase." Current Computer-Aided Drug Design 16, no. 3 (June 2, 2020): 281–94. http://dx.doi.org/10.2174/1573409915666190710092032.
Повний текст джерелаАнотація:
Background: Piperine or piperic acid was isolated from fruits of Piper nigrum and had been reported as pharmacological valuable bioactive constituents. Keeping in view, a series of piperic acid-based N heterocyclic’s derivatives were synthesized and evaluated for antibacterial activity. All these prepared ligands were docked to study the molecular interactions and binding affinities against the protein PDB ID: 5 CDP. Objective: To meet the real need of newer antibacterials, we designed and synthesized scaffolds with good antibacterial activity. The obtained antibacterials have been validated in terms of ligand-protein interaction and thus prove to build up as good drug candidates. Methods: Antibacterial activity of the compounds were carried out against bacterial strains; three Grampositive and three Gram-negative bacterial strains using agar well diffusion method. In silico molecular docking studies were carried out using Glide (grid-based ligand docking) program incorporated in the Schrödinger molecular modeling package by Maestro 11.0. Results: Compounds BC 28, BC 32, and BC 33 exhibits antibacterial activity along with Glide docking score of -8.580, -9.753 kcal/mol, and -8.813 kcal/mol, respectively. Docking studies explained hydrogen bonding, pi-pi, and hydrophobic interactions with amino acid residues which explain the binding affinity of the most docked ligand with protein. Conclusion: In the present study, substituted piperic acid was synthesized and evaluated as antibacterial compared with standard drug ciprofloxacin and results interpret that having nitrogen as heteroatom in the heterocyclic nucleus found to be more potent than the standard drug ciprofloxacin. On comparing, substitution with electron-donating groups generates excellent antibacterial potential against the bacterial strains. It was also proved that having substitution with electron-donating groups on meta and para position with triazoline ring system exhibits greater potential while compounds which have a meta- electron-donating substituent showed lesser activity with thiazole nucleus. In addition, structure-based activities of the prepared analogs were discussed under Structure-Activity Relationship (SAR) section.
8
Mangena, F. "Ethno-philosophy is Rational: A Reply to Two Famous Critics." Thought and Practice 6, no. 2 (July 21, 2015): 23–38. http://dx.doi.org/10.4314/tp.v6i2.3.
Повний текст джерелаАнотація:
In this article, I contend that philosophical reactions against ethno-philosophy, especially the arguments by professional African philosophers such as Paulin Hountondji and Kwame Anthony Appiah, cannot go unchallenged at a time when Africa is facing a myriad of problems such as disease, famine, ethnic conflicts, religious wars, and natural disasters which, in my view, stem from the continent’s failure to reflect on its past in the quest for lasting solutions. Having looked at the historical context of the emergence of ethno-philosophy or the project of cultural revivalism, and having closely examined the premises presented by Hountondji and Appiah against ethno-philosophy - which I consider to be unconvincing because of their tendency to glide into Western philosophical forms of thought - I argue that ethno-philosophy is just like Western philosophy, as it is based on a recognized form of reasoning, namely inductive reasoning, packaged in proverbs, riddles and other cultural resources. I also argue that religious beliefs are not an obstacle to the development of scientific thought in Africa; rather, they are an aid to it since both have complementary rather than opposing roles. KeywordsPhilosophy, ethno-philosophy, primitive unanimity, induction, African proverbs
9
Roman, Chris, and Dave Hebert. "Concept Tests for a New Wire Flying Vehicle Designed to Achieve High Horizontal Resolution Profiling in Deep Water." Journal of Atmospheric and Oceanic Technology 28, no. 12 (December 1, 2011): 1657–71. http://dx.doi.org/10.1175/jtech-d-10-05040.1.
Повний текст джерелаАнотація:
Abstract Efficiently profiling the water column to achieve both high vertical and horizontal resolution from a moving vessel in deep water is difficult. Current solutions, such as CTD tow-yos, moving vessel profilers, and undulating tow bodies, are limited by ship speed or water depth. As a consequence, it is difficult to obtain oceanographic sections with sufficient resolution to identify many relevant scales over the deeper sections of the water column. This paper presents a new concept for a profiling vehicle that slides up and down a towed wire in a controlled manner using the lift created by wing foils. The wings provide a novel low-power method of propulsion along the cable by using the free stream velocity of the wire moving through the water in similar fashion to a sailboat sailing up wind. Scale model tests show a wide range of achievable profiling glide slopes for tow cable angles between vertical and 45°, and effective isolation of cable strum vibration from the towed vehicle body. The concept is not depth limited and will offer two-dimensional resolution that meets or exceeds current undulating tow bodies over the full water column. Additionally, this system could be used simultaneously with many other deep towed instrument packages to produce complementary datasets.
10
Steinmann, Casper, and Jan H. Jensen. "Using a genetic algorithm to find molecules with good docking scores." PeerJ Physical Chemistry 3 (May 17, 2021): e18. http://dx.doi.org/10.7717/peerj-pchem.18.
Повний текст джерелаАнотація:
A graph-based genetic algorithm (GA) is used to identify molecules (ligands) with high absolute docking scores as estimated by the Glide software package, starting from randomly chosen molecules from the ZINC database, for four different targets: Bacillus subtilis chorismate mutase (CM), human β2-adrenergic G protein-coupled receptor (β2AR), the DDR1 kinase domain (DDR1), and β-cyclodextrin (BCD). By the combined use of functional group filters and a score modifier based on a heuristic synthetic accessibility (SA) score our approach identifies between ca 500 and 6,000 structurally diverse molecules with scores better than known binders by screening a total of 400,000 molecules starting from 8,000 randomly selected molecules from the ZINC database. Screening 250,000 molecules from the ZINC database identifies significantly more molecules with better docking scores than known binders, with the exception of CM, where the conventional screening approach only identifies 60 compounds compared to 511 with GA+Filter+SA. In the case of β2AR and DDR1, the GA+Filter+SA approach finds significantly more molecules with docking scores lower than −9.0 and −10.0. The GA+Filters+SA docking methodology is thus effective in generating a large and diverse set of synthetically accessible molecules with very good docking scores for a particular target. An early incarnation of the GA+Filter+SA approach was used to identify potential binders to the COVID-19 main protease and submitted to the early stages of the COVID Moonshot project, a crowd-sourced initiative to accelerate the development of a COVID antiviral.
Дисертації з теми "Glyde Package"
1
McFadzean, G. J. "Geochemical analysis of the McArthur and Tawallah Groups, McArthur Basin: chemostratigraphy & palaeo-redox proxies using shales and carbonates." Thesis, 2019. https://hdl.handle.net/2440/136976.
Повний текст джерелаАнотація:
This item is only available electronically.The lower portion of the McArthur Basin includes the Palaeoproterozoic to Mesoproterozoic McArthur and Tawallah Groups. During this time, Earth had comparatively less oxygen following the beginning of ‘The Great Oxygenation Event’ (GOE, Palaeoproterozoic ca. 2.34 Ga) and organisms were simple. In conjunction, the ‘Boring Billion’ (1800 to 800 Ma) is an acknowledged period following the GOE due to reported flat carbon and oxygen isotope trends which is evidence for a relatively stable climate and delayed organism evolution. The aim of this thesis is to gather a coupled dataset using conventional geochemistry and organic geochemistry through the use of carbon/oxygen isotopes, redox sensitive trace elements (Mo, V and U), rare earth elements and organic carbon content in order to understand the oxygen conditions (through palaeo-redox techniques) within the lower portions of the Palaeoproterozoic McArthur Basin. Shale units of the McArthur and Tawallah groups (Mallapunyah, Wollogorang and Wuraliwuntya Formations) are shown to be deposited in a stratified oxygenation and sulfidic environment. These episodes of anoxia or euxinia are shown by elevated concentrations of rare earth elements (REE) and trace elements at specific drill core depth. Subtle and fluctuating cerium and europium anomalies along with trace and major elemental data were coupled by total organic carbon (TOC) to show a relationship with the organic matter within the Wollogorang Formation specifically. The trace elements seemingly concentrated within the regions of high organic content, which resulted in euxinia events causing elevated levels of trace metals. Potential trace metal elevations within the Wollogorang and Mallapunyah Formations specifically are compared against the reported evidence for sedimentary exhalative deposits (SedEX deposits). The Amelia Dolostone recorded carbon isotope values of 0 to -2‰ and oxygen isotope values of -5 to -9‰ - expected carbon and oxygen isotopic concentrations for the Palaeoproterozoic to Mesoproterozoic Era.
Thesis (B.Sc.(Hons)) -- University of Adelaide, School of Physical Sciences, 2019
Тези доповідей конференцій з теми "Glyde Package"
1
Sandstro¨m, Rolf, and Henrik C. M. Andersson. "Creep During Power-Law Breakdown in Phosphorus Alloyed Copper." In ASME 2007 Pressure Vessels and Piping Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/creep2007-26518.
Повний текст джерелаАнотація:
Copper alloyed with 50 ppm phosphorus (Cu-OFP) is selected for canisters for nuclear waste packages to avoid a low creep ductility, which is sometimes present in pure copper. The operating temperatures of these canisters are in the range from 0 to 100°C. Creep readily takes place in copper even at room temperature. At temperatures below 100°C, creep is well inside the power-law breakdown regime. The creep exponent is in the range from 30 to 100. Since creep models for this situation are missing in the literature, a new model for the minimum creep rate based on fundamental principles for climb and glide has been derived. This model gives the correct order of magnitude for the creep rate in the temperature range from 20 to 400°C without the use of fitted parameters. Design against creep can either be based on the total applied stress or the effective stress. In the first case the constitutive equations can be directly obtained from the minimum experimental creep rates. A new approach is proposed to handle the effective stress case, which is based on the initial creep rates. The φ-model is used to relate the initial creep rate to the minimum one. It is shown how the constitutive equations for the creep rate and the back stress can be transferred to multiaxial stress states for use in FE-modelling.