Добірка наукової літератури з теми "Glucose ester"
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Статті в журналах з теми "Glucose ester"
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Leclercq-Meyer, Viviane, and Willy J. Malaisse. "Dual mode of action of glucose pentaacetates on hormonal secretion from the isolated perfused rat pancreas." American Journal of Physiology-Endocrinology and Metabolism 275, no. 4 (October 1, 1998): E610—E617. http://dx.doi.org/10.1152/ajpendo.1998.275.4.e610.
Повний текст джерелаАнотація:
Isolated perfused rat pancreases were exposed, in the presence of 10.0 mMl-leucine, to either α-d-glucose pentaacetate, β-l-glucose pentaacetate, or unesterified d-glucose, all tested at a 1.7 mM concentration. The pentaacetate ester of α-d-glucose and, to a lesser extent, that of β-l-glucose stimulated both insulin and somatostatin release, whereas unesterifiedd-glucose failed to do so. In the case of insulin output, the two esters differed from one another not solely by the magnitude of the secretory response but also by its time course and reversibility. Compared with these data, the most salient difference found in the case of somatostatin release consisted of the absence of an early secretory peak in response to α-d-glucose pentaacetate administration and the higher paired ratio between the secretory responses evoked by the esters of glucose and by unesterifiedd-glucose (5.5 mM) administered at the end of the experiments. The two esters provoked an initial and short-lived stimulation of glucagon secretion, in sharp contrast to the immediate inhibitory action of unesterifiedd-glucose. Thereafter, α-d-glucose pentaacetate, but not β-l-glucose pentaacetate, caused inhibition of glucagon release, such an effect being reversed when the administration of the ester was halted. These findings indicate a dual mode of action of glucose pentaacetate esters on hormonal secretion from the endocrine pancreas. The intracellular hydrolysis of α-d-glucose pentaacetate and subsequent catabolism of its hexose moiety may contribute to the early peak-shaped insulin response to this ester, to the persistence of a positive secretory effect in B and D cells after cessation of its administration, and to the late inhibition of glucagon release. However, a direct effect of the esters themselves, by some as-of-yet unidentified coupling process, is postulated to account for the stimulation of insulin and somatostatin release by β-l-glucose pentaacetate and for the initial enhancement of glucagon secretion provoked by both glucose esters.
2
Malaisse, W. J., and A. Sener. "Metabolic effects and fate of succinate esters in pancreatic islets." American Journal of Physiology-Endocrinology and Metabolism 264, no. 3 (March 1, 1993): E434—E440. http://dx.doi.org/10.1152/ajpendo.1993.264.3.e434.
Повний текст джерелаАнотація:
The metabolic effects and the catabolism of succinate methyl esters were examined in rat pancreatic islets. The esters augmented 14CO2 production from islets prelabeled with L-[U-14C]-glutamine but inhibited NH4+ output, suggesting that they do not activate glutamate dehydrogenase. They decreased 14CO2 output from islets prelabeled with [U-14C]palmitate. They had little effect on the oxidation of exogenous D-[3,4-14C]glucose, D-[2-14C]glucose, D-[6-14C]glucose, or D-[1-14C]glucose, suggesting unaltered ratio between the input of acetyl residues and four- or five-carbon metabolites, such as succinate, into the Krebs cycle. By following the fate of both [1,4-14C]succinate dimethyl ester and [2,3-14C]succinate dimethyl ester, data were obtained to indicate that succinate is efficiently formed from the ester and further metabolized, leading to the generation of 14C-labeled acidic metabolites including pyruvate and L-lactic acid, CO2, and amino acids. It is proposed that a concerted increase of both succinate and acetyl residue influx into the Krebs cycle accounts for the increase in O2 uptake caused by the succinate methyl esters and, hence, for stimulation of both pro-insulin biosynthesis and insulin release.
3
Nottingham, Stephen F., Orestes T. Chortyk, and Michael G. Stephenson. "Sugar Esters from Nicotiana Species as Potential Insecticides Against the Sweetpotato Whitefly (Homoptera: Aleyrodidae)." Journal of Entomological Science 31, no. 3 (July 1, 1996): 331–39. http://dx.doi.org/10.18474/0749-8004-31.3.331.
Повний текст джерелаАнотація:
Eight Nicotiana species and three species accessions were grown and their sugar esters were isolated. Nicotiana trigonophylla, N. palmeri, and N. glutinosa gave the highest sugar ester yields. Sugar ester isolates were bioassayed at concentrations from 1.0 to 0.05 mg/ml against nymphs of Bemisia tabaci (Gennadius) (Homoptera: Aleyrodidae). The highest mortalities were observed with isolates from N. gossei and N. langsdorffii. As the sugar ester isolate from N. gossei contained both sucrose esters and glucose esters, these were bioassayed separately and both caused high mortality. The isolates of three N. glutinosa accessions varied in sucrose ester and labdane terpenoid content; labdane fractions were less toxic than sucrose ester fractions. Nicotiana glutinosa 24, N. langsdorffii, and N. trigonophylla, in addition to N. gossei, showed good potential as sources of biorational insecticide against whitefly.
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Ashraf-Khorassani, M., N. Nazem, LT Taylor, and WM Coleman. "Isolation, Fractionation, and Identification of Sucrose Esters from Various Oriental Tobaccos Employing Supercritical Fluids." Beiträge zur Tabakforschung International/Contributions to Tobacco Research 23, no. 1 (April 1, 2008): 32–45. http://dx.doi.org/10.2478/cttr-2013-0846.
Повний текст джерелаАнотація:
AbstractIsolation, fractionation, and identification of sucrose esters from aged oriental tobacco employing supercritical fluids have been completed. Underivatized sucrose ester-rich extracts were obtained using supercritical CO2 at densities greater than 0.73 g/mL. Lower density CO2 provided extracts with notable amounts of tobacco derived material; yet, no detectable sucrose ester content. Preparative supercritical fluid chromatography (SFC) provided for an additional purification of the sucrose ester-enriched fraction after column optimization. Structural assignments of the SFC fractions were facilitated using gas chromatography/mass spectrometry (GC/MS) accompanied by N, O-bis(trimethylsilyl)trifluoroacetamide-dimethylformamide (BSTFA-DMF) derivatization of the free hydroxyl groups and high performance-liquid chromatography/mass spectrometry (HPLC/MS). From a relative quantitative perspective regardless of tobacco type, sucrose esters having an acetyl group on C6 of the glucose function (Group III) were in higher concentration compared to both the concentration observed for sucrose ester of Group I (acetyl group on C3 of fructose) and sucrose ester of Group II (no acetyl group on either glucose or fructose). Saturated fatty acid constituents were found to range from a maximum total of 18 carbons to a minimum total of 13 carbons. Unsaturated and isomeric fatty acid homologues were detected within the Group II sucrose ester.
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Gross, Georg G., and Klaus Denzel. "Enzymatic Synthesis of Di-O-Phenylcarboxyl-ß-D-glucose Esters by an Acyltransferase from Oak Leaves." Zeitschrift für Naturforschung C 45, no. 1-2 (February 1, 1990): 37–41. http://dx.doi.org/10.1515/znc-1990-1-208.
Повний текст джерелаАнотація:
Leaves from oak (Quercus robur) contain an acyltransferase that catalyzes the conversion of β-glucogallin (1-O-galloyl-β-D-glucose) to 1,6-di-O-galloylglucose, an intermediate in the biosynthesis of gallotannins. Substrate specificity studies revealed th at this enzyme was also active with several structurally related 1-O-phenylcarboxyl-β-D-glucoses; appreciable reaction rates, however, were observed only in the form ation of 1,6-di-O-protocatechuoyl-β-D-glucose. This to date unknown ester, as well as its digalloyl analog, was synthesized using acyltransferase immobilized on phenyl-Sepharose, and characterized by UV and 1H NMR spectroscopy. In addition, the 1,2-di-O-β-D-glucose esters of benzoic and anisic acid were obtained in this investigation.
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Chang, Chin-Feng, Li-Chun Chen, Cheng-Jer Hsieh, Kai-Chun Chang, and Jung-Jeng Su. "Characterization of polyhydroxyalkanoate-producing bacteria isolated from sludge of commercial pig farms for producing methyl esters." Water Science and Technology 68, no. 10 (October 24, 2013): 2171–77. http://dx.doi.org/10.2166/wst.2013.474.
Повний текст джерелаАнотація:
The objectives of this work were to isolate and characterize the polyhydroxyalkanoate (PHA) producing bacteria in enriched piggery sludge and make methyl esters from PHA for industrial applications. The strain ECAe24 isolated from piggery sludge with the highest PHA production was selected to produce PHA and then methyl ester by trans-esterification using glucose as substrate under mesophilic conditions. The final product after trans-esterification consisted of approximately 75.39% of fatty acid methyl ester and was identified as decanoic acid-3-hydroxy-methyl ester, octanoic acid-3-hydroxy-methyl ester, and some other contents. The novelty of this study is to use PHA-producing bacteria from piggery sludge to make fatty acid methyl esters which can be used as materials for producing biodiesel from piggery wastes.
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Wright, David C., Paige C. Geiger, Mark J. Rheinheimer, Dong Ho Han, and John O. Holloszy. "Phorbol esters affect skeletal muscle glucose transport in a fiber type-specific manner." American Journal of Physiology-Endocrinology and Metabolism 287, no. 2 (August 2004): E305—E309. http://dx.doi.org/10.1152/ajpendo.00082.2004.
Повний текст джерелаАнотація:
Recent evidence has shown that activation of lipid-sensitive protein kinase C (PKC) isoforms leads to skeletal muscle insulin resistance. However, earlier studies demonstrated that phorbol esters increase glucose transport in skeletal muscle. The purpose of the present study was to try to resolve this discrepancy. Treatment with the phorbol ester 12-deoxyphorbol-13-phenylacetate 20-acetate (dPPA) led to an ∼3.5-fold increase in glucose transport in isolated fast-twitch epitrochlearis and flexor digitorum brevis muscles. Phorbol ester treatment was additive to a maximally effective concentration of insulin in fast-twitch skeletal muscles. Treatment with dPPA did not affect insulin signaling in the epitrochlearis. In contrast, phorbol esters had no effect on basal glucose transport and inhibited maximally insulin-stimulated glucose transport ∼50% in isolated slow-twitch soleus muscle. Furthermore, dPPA treatment inhibited the insulin-stimulated tyrosine phosphorylation of insulin receptor substrate (IRS)-1 and the threonine and serine phosphorylation of PKB by ∼50% in the soleus. dPPA treatment also caused serine phosphorylation of IRS-1 in the slow-twitch soleus muscle. In conclusion, our results show that phorbol esters stimulate glucose transport in fast-twitch skeletal muscles and inhibit insulin signaling in slow-twitch soleus muscle of rats. These findings suggest that mechanisms other than PKC activation mediate lipotoxicity-induced whole body insulin resistance.
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Malaisse, Willy J., Carmen Sánchez-Soto, M. Elena Larrieta, Marcia Hiriart, Hassan Jijakli, Concepción Viñambres, María L. Villanueva-Peñacarrillo та ін. "Insulinotropic action of α-d-glucose pentaacetate: functional aspects". American Journal of Physiology-Endocrinology and Metabolism 273, № 6 (1 грудня 1997): E1090—E1101. http://dx.doi.org/10.1152/ajpendo.1997.273.6.e1090.
Повний текст джерелаАнотація:
The functional determinants of the insulinotropic action of α-d-glucose pentaacetate were investigated in rat pancreatic islets. The ester mimicked the effect of nutrient secretagogues by recruiting individual B cells into an active secretory state, stimulating proinsulin biosynthesis, inhibiting86Rb outflow, and augmenting45Ca efflux from prelabeled islets. The secretory response to the ester was suppressed in the absence of Ca2+ and potentiated by theophylline or cytochalasin B. The generation of acetate from the ester apparently played a small role in its insulinotropic action. Thus acetate, methyl acetate, ethyl acetate, α-d-galactose pentaacetate, and β-d-galactose pentaacetate all failed to stimulate insulin release. The secretory response to α-d-glucose pentaacetate was reproduced by β-d-glucose pentaacetate and, to a lesser extent, by β-l-glucose pentaacetate. It differed from that evoked by unesterifiedd-glucose by its resistance to 3- O-methyl-d-glucose,d-mannoheptulose, and 2-deoxy-d-glucose. It is concluded that the insulinotropic action of α-d-glucose pentaacetate, although linked to the generation of the hexose from its ester, entails a coupling mechanism that is not identical to that currently implied in the process of glucose-induced insulin release.
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Zhang, T. M., H. Jijakli, and W. J. Malaisse. "Nutritional efficiency of succinic acid and glutamic acid dimethyl esters in colon carcinoma cells." American Journal of Physiology-Gastrointestinal and Liver Physiology 270, no. 5 (May 1, 1996): G852—G859. http://dx.doi.org/10.1152/ajpgi.1996.270.5.g852.
Повний текст джерелаАнотація:
The dimethyl esters of succinic acid (SAD) and glutamic acid (GME) were found to be efficiently metabolized in colon carcinoma cells of the Caco-2 line. The rate of [1,4-14C]SAD and [2,3-14C]SAD conversion to radioactive acidic metabolites, CO2, amino acids, pyruvic acid, and lactic acid suggested that the catabolism of the ester-derived succinic acid occurred mainly through the sequence of reactions catalyzed by succinate dehydrogenase, fumarase, and the malic enzyme. This coincided with a marked sparing action of SAD on the utilization of D-[2-(3)H]glucose and D-[5-(3)H]glucose and generation of 14C-labeled acid metabolites, CO2, and lactic acid from D-[U-14C]glucose by the enterocytes. Likewise, the conversion of [U-14C]GME to 14C-labeled amino acids, its oxidation compared with that of [1-(14)C]GME, and the production of NH4+ in the absence or presence of GME indicated efficient catabolism of the latter ester. Like SAD, GME decreased the utilization of D-[5-(3)H]glucose and generation of 14C-labeled acidic metabolites, pyruvate, and CO2 from D-[6-(14)C]glucose, while increasing the generation of 14C-labeled amino acids from the labeled hexose. The oxidation of D-[6-(14)C]glucose was even more severely inhibited by GME. In normal rat intestinal cells, SAM, SAD, and GME also exerted a marked sparing action on D-[U-14C]glucose oxidation. The present findings suggest, therefore, that these esters could possibly be used to sustain ATP generation in intestinal cells.
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Roberts, Dennis A., Liyi Wang, Weihe Zhang, Yi Liu, Pratik Shriwas, Yanrong Qian, Xiaozhuo Chen, and Stephen C. Bergmeier. "Isosteres of ester derived glucose uptake inhibitors." Bioorganic & Medicinal Chemistry Letters 30, no. 18 (September 2020): 127406. http://dx.doi.org/10.1016/j.bmcl.2020.127406.
Повний текст джерелаДисертації з теми "Glucose ester"
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Omosa, Haron Moeti. "Studies on Several Diacetone-Glucose-derived Esters." Youngstown State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=ysu1628676922903541.
Повний текст джерела
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Xuan, Wenxiang. "Glucose Levulinates as Bio-plasticizers." Thesis, KTH, Skolan för kemivetenskap (CHE), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-218153.
Повний текст джерелаАнотація:
Glucose, as the most plentiful sugar in nature, is a renewable resource and possesses excellent record in health safety. Levulinic acid is a platform chemical which plays an important role in biomass transformation and reactive intermediates. Both glucose and levulinic acid can be produced by biomass conversion with green processing techno logies. Due to the rising needs for bio-based, eco-friendly and non-toxic plasticizers, glucose levulinates as bio plasticizers were synthesized from glucose and levulinic acid, by utilizing microwave radiation or conventional condensation reaction (direct-heating method ). Acid number for the reaction liquor was measured by acid-base titration to follow the decrease of acid groups due to the reaction and the trend in the acid number within reaction time displayed the process of esterification and possible sensitivity of the reaction rate to reaction scale. It showed that microwave radiation had superior ability in enhancing reaction speed but it was also more sensitive to reaction scale and generated more diverse prod ucts than the direct-heating method. Besides, the process of reaction and formation of ester bonds was followed and confirmed by FT IR. The achieved levulinate products were extracted by 2-pro panol and ethyl acetate. The practices showed several serio us problems in 2-propanol extraction, including high dosage required for NaCl and solvent and difficulties in purification. The ethyl acetate proved to be a suitable solvent for this study and the extrac ted product s from the Con-24hrs and Micro-3/4/5/6/7hrs were characterized by 1H NMR, 13C N :tvlR. and LDI-MS. The results from spectrum suggested the presence of GL,. and G J .'l. type of levulinates. That means the glucose levulinates were successfully synthesized although the dehydration side reaction of glucose was inevitable leading to the generation of glucosidic bonds. In addition, BG (mixture of glucose and glycosidic levulinates) was evaluated by so lution casting of starch and PVC. In order to minimize the microbial contaminations in solution casting of starch, a modified method was raised and applied. The results showed that 40% BG had goo d miscibility with starch and the conclusion was further proved by DSC measurements, while the BG performed poor miscibility with PVC.
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Koumba, Ibinga Sidrine Kerthy. "Coupure de liaisons glycosidiques de la biomasse saccharifère couplée à la formation de liaisons esters amphiphiles." Thesis, Toulouse, INPT, 2020. http://www.theses.fr/2020INPT0062.
Повний текст джерелаАнотація:
En 2030, la chimie du végétal occupera 30% de la chimie totale en France. Les bioressources offrent l’opportunité de substituer les produits issus de la pétrochimie. Avec un taux de pénétration stable de 25-30% selon les prévisions de l’ADEME, les biotensioactifs constituent une voie de valorisation des produits issus de l’agriculture. Les sources lipophiles et hydrophiles nécessaires à l’obtention de ces composés amphiphiles peuvent être totalement naturelles. Ainsi, la graine de chia de la variété Oruro® a été utilisée comme source de la partie hydrophile représentée par le mucilage. Le mucilage surfacique de la graine de cette variété domestiquée en France est constitué de polysaccharides, de protéines et de minéraux. Il peut être extrait de façon efficace par cavitation ultrasonore en milieux aqueux. La composition et les propriétés du mucilage sont liées au temps d’extraction. Ce mucilage constitue une source hydrophile pour l’obtention d’esters amphiphiles. La source lipophile choisie est l’amande de Irvingia gabonensis issue d’une variété riche en beurre laurique haut myristique (51%) et laurique (38%). Les triglycérides de ce beurre sont constitués par des mélanges en acides gras saturés. Ce sont de bons candidats pour l’alimentation, la nutrition et aussi l’industrie et la production de biotensioactifs technofonctionnels. Le travail vise donc la valorisation simultanée du mucilage et de l’huile de I. gabonensis par la synthèse de biotensioactifs. Deux voies de synthèse pour l’obtention des esters amphiphiles ont été explorées. La première voie a impliqué la mise en œuvre de la réaction de transestérification entre le glucose et le laurate de méthyle en milieu eutectique profond DES Chlorure de choline/glucose. La deuxième voie fait appel à la catalyse acide en milieu organisé par la mise en œuvre de la réaction d’estérification du glucose ou du mucilage avec les acides gras laurique C12:0, et myristique C14:0 en présence de l’acide dodécylbenzène sulfonique (ADBS). Les études des réactions d’estérification ont préalablement été réalisées à partir du glucose puis transposées au mucilage. L’utilisation de l’ADBS doté d’un double rôle en tant que catalyseur de Brönsted et tensioactif favorise la mise en contact des réactifs, catalyse la réaction la réaction d’estérification entre les hydroxyles du glucose ou des polysaccharides et les groupes carboxyliques des acides gras laurique C12:0 et myristique C14:0 et par conséquent permet l’obtention des esters de glucose de degré de substitution DS=1-2. Les propriétés tensioactives et émulsionnantes sont comparables de ces esters de glucose sont comparables à celles d’un ester commercial Olivem 1000, un mélange d’olivate de sorbitan et d’olivate de cétéaryl. La réaction entre le mucilage de chia Oruro® et le mélange d’acides gras de I. gabonensis en présence de l’ADBS a permis une modification structurale profonde du biopolymère. Sa lipophilisation est obtenue par la double monoacylation des sites hydroxyles du mucilage par le mélange d’acides gras laurique C12:0 et myristique C14:0. La viscosité intrinsèque du mucilage acylé est très faible (6,34 dL/g) par rapport à celle du mucilage brut (36,18 dL/g) utilisé en tant que réactif de départ. Il en découle un changement profond de propriétés techno-fonctionnelles du mucilage acyléIn 2030, vegetal-based chemistry will occupy 30% of total chemistry in France. Bioresources offer the opportunity to substitute products from petrochemicals. With a stable penetration rate of 25- 30% according to ADEME forecasts, biosurfactants are a way of adding value to agricultural products. The lipophilic and hydrophilic sources needed to obtain these amphiphilic compounds can be completely natural. Thus, the chia seed of the Oruro® variety has been used as a source of the hydrophilic part represented by the mucilage. The surface mucilage of the seed of this variety domesticated in France is made up of polysaccharides, proteins and minerals. It can be extracted effectively by ultrasonic cavitation in aqueous media. The composition and properties of the mucilage are related to the extraction time. This mucilage constitutes a hydrophilic source for obtaining amphiphilic esters. The lipophilic source chosen is the Irvingia gabonensis almond from a variety rich in high myristic (51%) and lauric (38%) butter. The triglycerides of this butter are made up of mixtures of saturated fatty acids. They are good candidates for food, nutrition and also industry and production of technofunctional biosurfactants. The work is therefore aimed at the simultaneous valorization of the mucilage and oil of I. gabonensis by the synthesis of biosurfactants. Two synthesis routes for obtaining amphiphilic esters have been explored. The first pathway involved the implementation of the transesterification reaction between glucose and methyl laurate in a deep eutectic medium DES Choline chloride/glucose. The second pathway involved acid catalysis in an organized medium by the implementation of the esterification reaction of glucose or mucilage with lauric C12:0 and myristic C14:0 fatty acids in the presence of dodecylbenzene sulfonic acid (DBSA). The studies of the esterification reactions were previously carried out using glucose and then transferred to mucilage. The use of DBSA with a dual role as a Brönsted catalyst and surfactant promotes the contact of the reagents, catalyzes the esterification reaction between the hydroxyl groups of glucose or polysaccharides and the carboxylic groups of the C12:0 lauric and C14:0 myristic fatty acids and therefore allows the glucose esters of degree of substitution DS=1-2 to be obtained. The surfaceactive and emulsifying properties of these glucose esters are comparable to those of a commercial Olivem 1000 ester, a mixture of sorbitan olivate and cetearyl olivate. The reaction between chia Oruro® mucilage and the fatty acid mixture of I. gabonensis in the presence of ADBS resulted in a profound structural modification of the biopolymer. Its lipophilization is obtained by the double monoacylation of the hydroxyl sites of the mucilage by the mixture of lauric C12:0 and myristic C14:0 fatty acids. The intrinsic viscosity of the acylated mucilage is very low (6.34 dL/g) compared to that of the crude mucilage (36.18 dL/g) used as starting reagent. This results in a profound change in the techno-functional properties of the acylated mucilage
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Tanti, Jean-François. "Rôle de la protéine kinase C et de la protéine kinase dépendante de l'AMPc dans la modulation de l'activité tyrosine kinase du récepteur de l'insuline et dans le mécanisme d'action de l'hormone." Nice, 1988. http://www.theses.fr/1988NICE4218.
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Patras, Maria Alexandra [Verfasser], Nikolai [Akademischer Betreuer] Kuhnert, Matthias [Gutachter] Ullrich, and Ulrich [Gutachter] Engelhardt. "Mass Spectrometrical Analysis of Flavonoids and Glucose Esters of Hydroxycinnamic Acids in Dietary Plants / Maria Alexandra Patras ; Gutachter: Matthias Ullrich, Ulrich Engelhardt ; Betreuer: Nikolai Kuhnert." Bremen : IRC-Library, Information Resource Center der Jacobs University Bremen, 2018. http://d-nb.info/1166950719/34.
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Green, Katherine J. "The effect of acute exercise on T-lymphocyte function." Thesis, Queensland University of Technology, 2002. https://eprints.qut.edu.au/36777/1/36777_Digitised%20Thesis.pdf.
Повний текст джерелаАнотація:
An increased incidence of illness has been observed in athletic populations undergoing intensive training and competition. T-lymphocytes are central to cell-mediated adaptive immune responses and have been the subject of many studies investigating the relationship between T-lymphocyte function, exercise and athlete health. A decrease in T-lymphocyte function following acute intensive exercise has commonly been described, making them a possible factor contributing to increased susceptibility in athlete populations. However, there is much controversy regarding the interpretation of traditional methodology (mitogen-induced proliferation assays) used to assess Tlymphocyte function during and after exercise. Current lymphocyte proliferation assays do not determine individual T-lymphocyte function or independently establish the function of T-lymphocyte subsets. Therefore, the overall aim of this thesis was to develop and apply new techniques to the study of the effect of acute exercise on the function of T-lymphocytes. Specifically, this thesis aimed to determine the effect of acute intensive exercise on the function of individual T-lymphocytes and T-lymphocyte subsets. The major findings of this thesis are that acute intensive exercise does impair Tlymphocyte responses to mitogen. The cellular expansion of both CD4 and CD8 Tlymphocytes as measured by the application of the new CFSE technique is decreased by acute exercise. The exercise effect observed is not an initial effect on cell function, as exercise does not impair the ability of T-lymphocytes to respond to stimulus (activation) and undergo cell division (mitosis) in response to mitogen. Instead, acute exercise is associated with an increased level of apoptosis in mitogen-stimulated cultures and this results in a reduction of the overall expansion of the cell population in vitro. The mechanism by which exercise induces apoptosis was examined using carbohydrate supplementation and it was found that carbohydrate feeding can prevent exercise-induced apoptosis, and hence attenuates the decrease in T-lymphocyte function. However, the mechanism by which carbohydrate prevents apoptosis does not appear to be via moderation of T-lymphocyte numbers or blood cortisol concentrations, rather it may be due to improved glucose availability.
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AOUAD, MOHAMMED EL ARABI. "-d-o-glycosides de phenols, chalcones, benzalacetones et esters de -d-glucosyle d'acides phenoliques. Syntheses et activites comme inducteurs de genes de virulence." Amiens, 1994. http://www.theses.fr/1994AMIES041.
Повний текст джерелаАнотація:
La methode de michael a ete utilisee pour la synthese de -o glycosides d'aryle afin de pouvoir etudier leurs activites comme inducteurs de genes de virulence. Ainsi ont ete synthetises 22 glycosides de derives phenoliques ayant une structure proche de celle de l'acetosyringone. Ensuite, des cetones , ethyleniques comme des chalcones, des benzalacetones et des dibenzalacetones ont ete preparees et glycosylees. Pour les chalcones dihydroxylees, la methode de michael a permis la glycosylation du cote du noyau phenolique portant un ou deux groupes methoxy. Pour acceder au greffage de l'autre cote, nous avons du realiser d'abord la glycosylation d'une cetone ou d'un aldehyde phenolique puis l'aldolisation de ces glycosides. L'acces direct aux -d-o-glycosides d'aryle a ete recherche par une methode originale sans protection prealable de la partie sucre. Il est possible de preparer des derives 1,2-sulfite cyclique et de le faire reagir ensuite avec un ion phenate pour obtenir le -o-glucoside stereoselectivement. Cette methode one pot ne necessite donc aucun groupe protecteur et nous a permis en particulier d'acceder directement a des -d-o-xylosides. Deja une grande majorite de ces produits ont ete testes au laboratoire d'androgenese et biotechnologie d'amiens et il a pu etre degage quelques caracteristiques structurales necessaires a leur efficacite comme inducteurs de genes de virulence
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Villas, Boas Julia Dias. "Reatividade a diferentes tipos de estresse em equinos atletas." Universidade Federal Rural do Rio de Janeiro, 2017. https://tede.ufrrj.br/jspui/handle/jspui/2433.
Повний текст джерелаАнотація:
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The horse has a natural predisposition for the sport, however, its use in competitions can result in stress related problems that impair its sporting performance and especially its health. In this way it is fundamental not only to understand how the different risk and resilience factors to different stressors influence the response to stress, but also to develop strategies that can prevent or minimize the deleterious effects of stress. In this sense, acupuncture is an ancient technique of Traditional Chinese Medicine that has been used in the treatment and prevention of stress-related diseases. The present study proposed the use of two models of stress: one physical (physical exercise) and another psychological (startle model) to verify the reactivity to the stress of athletes horses. In addition, it was also evaluated if horses of different sporting modalities present different psychological stress responses and if acupuncture can alter the responses to physical stress. In the experiment 1, 16 Thoroughbred race horses were submitted to a exercise in the field of high intensity and short duration (12 m / s, 4 min). The RR intervals for analysis of the Heart Rate Variability were acquired through the Polar Equine ? heart rate monitor and blood samples were collected before and immediately after 2h, 4h, 6h, and 24h after exercise. The exercise promoted autonomic alterations in the sympatho-vagal balance since it significantly increased the low frequency component (LF), the heart rate and the LF / HF ratio, and decreased the high frequency component (HF) (p <0.01). There was an increase in hematocrit, plasma proteins, glucose and plasma lactate immediately after exercise (p <0.001). There was an increase (p <0.01) in serum cortisol values after 30 minutes, returning to baseline values after 60 min. However, no significant difference was observed in plasma cytokines IL-1? and IL-6 between moments after exercise and baseline. In experiment 2, horses of the experimental group 1 after exercise were randomly divided into two groups: CTL (C2): Control (without manipulation) and ACUP (C2)): animals submitted to weekly sessions of acupuncture at points VG1, C7, VG20 and B52 for 10 weeks. After the treatment period the animals repeated the same exercise and the same parameters were analyzed. Acupuncture reduced the LF / HF ratio, promoting a faster recovery of the animals, showing no influence on the other parameters analyzed. In the experiment 3, 24 equines were used, from three equestrian modes: Polo (PSI) (n = 9), Dressage (Brazilian Horse Riding) (n = 6) and Endurance (n=6) were subjected to the experimental model of startling through the abrupt opening of an umbrella. The results showed that endurance horses presented a significantly less intense startle-induced autonomic response than Polo and Dressage horses (lower LF / HF ratio at the time of the jump), paradoxically Enduro horses have cortisol levels in response in response to the startle than Polo horses. However, there was no difference between the modalities in the behavioral response after the startle, and Polo horses had significantly higher baseline levels of cortisol than the other modalities and did not change their cortisol levels in response to stress. Thus, we can conclude that 1) the exercise in the field of high intensity and short duration promoted adaptive changes characteristic of stress, being able to be used in studies of reactivity to stress in race horses; 2) acupuncture has a modulating effect on the stress-induced autonomic response in athletic horses, and 3) the equestrian modalities of Dressage, Polo and Endurance present different stress reactivity
O cavalo tem uma predisposi??o natural para o esporte, no entanto, o seu uso em competi??es pode resultar em problemas relacionados ao estresse que prejudicam seu desempenho esportivo e principalmente a sua sa?de. Desta forma ? fundamental n?o apenas entender como os diferentes fatores de risco e de resili?ncia a diferentes estressores influenciam a resposta ao estresse, como tamb?m desenvolver estrat?gias que possam prevenir ou minimizar os efeitos delet?rios do estresse. Neste sentido a acupuntura ? uma t?cnica milenar da Medicina Tradicional Chinesa que tem sido utilizada no tratamento e preven??es de doen?as relacionadas ao estresse. O presente estudo prop?s o uso de dois modelos de estresse: um f?sico (exerc?cio f?sico) e outro psicol?gico (modelo de sobressalto) para verificar a reatividade ao estresse de cavalos atletas. Al?m disso, tamb?m foi avaliado se cavalos de diferentes modalidades esportivas apresentam respostas ao estresse de psicol?gico distintas e se acupuntura pode alterar as respostas ao estresse f?sico. No experimento 1, 16 equinos de corrida da ra?a Puro Sangue Ingl?s foram submetidos ao exerc?cio a campo de alta intensidade e curta dura??o (12 m/s, 4min). Os intervalos RR para an?lise da Variabilidade da Frequencia Card?aca foram adquiridos atrav?s do frequenc?metro card?aco Polar Equine? e as amostras de sangue foram coletadas antes e, imediatamente, 2h, 4h, 6h, e 24h ap?s o exerc?cio. O exerc?cio promoveu altera??es auton?micas no balan?o simpato-vagal uma vez que aumentou significativamente o componente de baixa frequ?ncia (LF), a frequ?ncia card?aca e a raz?o LF/HF e diminuiu o componente de alta frequ?ncia (HF) (p < 0.01). Houve aumento do hemat?crito, das prote?nas plasm?ticas, glicose e lactato plasm?tico imediatamente ap?s o exerc?cio (p < 0.001). Houve aumento (p<0.01) nos valores s?ricos de cortisol ap?s 30 minutos, retornando aos valores basais ap?s 60min. No entanto, n?o foi observado diferen?a significativa nas citocinas plasm?ticas IL-1? e IL-6 entre os momentos ap?s exerc?cio e o momento basal. No experimento 2: os equinos do experimento 1 ap?s o exerc?cio foram aleatoriamente divididos em dois grupos: CTL (C2): Controle (sem manipula??o) e ACUP (C2)ACUP (C2): animais submetidos a sess?es semanais de acupuntura nos pontos VG1, C7, VG20 e B52 durante 10 semanas. Ap?s o per?odo de tratamento os animais repetiram o mesmo exerc?cio e foram analisados os mesmos par?metros. A acupuntura reduziu a raz?o LF/HF, promovendo uma recupera??o mais r?pida dos animais n?o apresentando influ?ncia nos demais par?metros analisados. No experimento 3, foram utilizados 24 equinos, pertencentes a tr?s modalidades equetres: P?lo (ra?a PSI) (n=9), Adestramento (ra?a Brasileiro de Hipismo) (n=6) e Enduro (Puro Sangue ?rabe) (n=9) submetidos ao modelo experimental de sobressalto atrav?s da abertura abrupta de um guarda-chuva. Os resultados mostraram que cavalos de enduro apresentaram resposta auton?mica induzida pelo sobressalto significativamente menos intensa que cavalos de Polo e Adestramento (menor raz?o LF/HF no momento do sobressalto), paradoxalmente cavalos de Enduro possuem n?veis de cortisol em resposta ao sobressalto mais altos que cavalos de Polo. N?o houve diferen?a entre as modalidades na resposta comportamental ap?s o sobressalto, no entanto cavalos de P?lo apresentam n?veis basais de cortisol significativamente mais altos que as demais modalidades e n?o variaram seus n?veis de cortisol em resposta ao estresse. Dessa forma, podemos concluir que 1) o exerc?cio a campo de alta intensidade e curta dura??o promoveu altera??es adaptativas caracter?stica de estresse, podendo ser utilizado em estudos de reatividade ao estresse em cavalos de corrida; 2) a acupuntura tem um efeito modulador da resposta auton?mica induzida pelo estresse em cavalos atletas e 3) as modalidades equestres de Adestramento, Polo e enduro apresentam reatividade ao estresse distintas
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Giaccio, Joanne. "Precursors to the potent odorant wine lactone." Thesis, 2013. http://hdl.handle.net/2440/82465.
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This thesis describes the synthesis, hydrolysis and analysis of menthiafolic acid, a precursor to wine lactone in wine. (R)-Menthiafolic acid was synthesised and then taken through acid hydrolyses to confirm its conversion to wine lactone under wine-like conditions and to determine the chirality of the resultant product. A Gas Chromatography/ Mass Spectrometry (GC/MS) Stable Isotope Dilution Assay (SIDA) method was developed to analyse for this compound in grapes and wine. Chiral analysis was also carried out on wine extracts to confirm which enantiomers of menthiafolic acid and wine lactone are present in real wine samples. Bioconversion of the glucose ester of menthiafolic acid utilising three different microorganisms was evaluated in order to determine if menthiafolic acid is produced and hence if this compound is an indirect precursor to wine lactone through initial degradation to menthiafolic acid. Chapter 1 comprises an introduction and literature review.
Chapter 2 concerns the synthesis and acid hydrolysis of (R)-menthiafolic acid. The synthesis gave a mixture of 95% (R)-enantiomer and 5% (S)-enantiomer menthiafolic acid. Hydrolysis was carried out under mild, wine-like conditions and under harsh Simultaneous Distillation Extraction (SDE) conditions. These hydrolyses showed that this compound is, in fact, converted to wine lactone under wine-like conditions but both the ‘natural’ (-)-isomer of wine lactone and its enantiomer are produced in varying proportions depending on the hydrolytic conditions. This work has been published; Giaccio et al. Journal of Agricultural and Food Chemistry 2011, 59, 660. Chapter 3 describes the development of a SIDA method for the analysis of menthiafolic acid in grapes and wine. Extraction methods were investigated for model wine solutions and then transferred to white wine. A d₅-analogue of menthiafolic acid was prepared for use in later quantifications. Grapes and wines were analysed and menthiafolic acid was found in the wines in varying concentrations ranging from < 10 µg/L to 342 µg/L with the highest concentration found in a Lexia wine. Wines analysed showed menthiafolic acid in significant concentrations which could potentially produce wine lactone in concentrations above its aroma threshold. Grape analyses were also carried out and menthiafolic acid was observed in concentrations ranging from 16 µg/L to 235 µg/L. Gerwütztraminer grapes contained the greatest concentration of this precursor. Chiral analysis of menthiafolic acid present was also carried out on grape and wine samples. The analyses showed that the (S)-enantiomer of menthiafolic acid is the more prevalent enantiomer in these particular grape and wine samples. Chapter 4 concerns fermentation studies of the glucose ester of menthiafolic acid. The SIDA method discussed in Chapter 3 was used to analyse for menthiafolic acid in these samples in order to determine if menthiafolic acid is released from the glucose ester via fermentation with various yeast and bacteria. Approximately 15% bioconversion of the glucose ester to menthiafolic acid was observed when fermenting with Saccahormyces cerevisiae (strain AWRI 838). Bioconversion occurred to a lesser extent (approx. 5%) when fermenting with the lactic acid bacteria Oenococcus oeni (strain VP-41) and even less of the glucose ester was converted to menthiafolic acid when fermenting with spoilage yeast Dekkera bruxellensis (strain AWRI 1499). Menthiafolic acid was not observed in a concentration above the limit of quantification in D.bruxellensis fermentations. Chapter 5 details an attempt to develop a quantification method for wine lactone in model wine. Extraction of wine lactone from a white wine was also attempted. Chiral analysis of wine lactone extracted from wine by continuous liquid extraction was also conducted showing that the predominant enantiomer of wine lactone present in the wine analysed was, in fact, the (+)-enantiomer which has not previously been reported in wine. The (-)-enantiomer of wine lactone was also observed and the ratios of the two wine lactone enantiomers correlated with what was expected when taking into account the ratios of menthiafolic acid also present in the wine. Chapter 6 comprises the experimental methods, materials and instrumentation utilised in these studies.Thesis (Ph.D.) -- University of Adelaide, School of Agriculture, Food and Wine, 2013
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(6631871), Han Nguyen. "THIOL-NORBORNENE HYDROGELS WITH TUNABLE MECHANICAL PROPERTIES FOR ENGINEERED EXTRACELLULAR MATRICES." Thesis, 2019.
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The extracellular matrix (ECM) governs many cellular processes through biochemical and mechanical cues. Particularly, the effect ECM mechanical properties on cells fate has been well established over the years. Many hydrogel systems have been used to mimic the dynamic stiffening processes occurring in ECM. However, changes in ECM stiffness does not fully recapitulate the mechanics of native ECM, as viscoelasticity is also a major factor contributing to ECM dynamic property. This thesis describes the design and characterization of an enzyme-crosslinked hydrogel system that is not only capable of being stiffened on demand, but also can be tuned to obtain viscoelasticity. The first objective of this thesis was to utilize horseradish peroxidase (HRP) to crosslink thiol-norbornene hydrogel and use mushroom tyrosinase (MT) to create secondary DOPA-dimer crosslinks that stiffened the hydrogel. The cytocompatibility of HRP-mediated thiol-norbornene gelation and the effect of stiffening on cell fate was evaluated. The second objective of this thesis represented the first step towards developing a hydrogel system whose viscoelasticity could be dynamically tuned. Thiol-norbornene hydrogel was designed to yield dynamically adaptable boronic ester bonds via partial enzymatic reaction. Thiol-norborne hydrogel was made to contain hydroxyl phenol as well as boronic acid residues within its network. MT, in this case was used to oxidize the hydroxy phenol moieties into DOPA, which then complexed with boronic acid, created dynamic bonds, introducing viscoelasticity to an initial elastic hydrogel.
Книги з теми "Glucose ester"
1
Svensson, B. Martin. Enzymatic preparation of glucoside esters in microemulsion media. Norwich: University of East Anglia, 1992.
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Muñoz Arellano, Diana Lucero, Yunery Marlen Bautista Gómez, Andrea Ortega Mondragón, Ana Leticia Becerra Gálvez, and Leonardo Reynoso Erazo. Reducción de estrés en pacientes con Diabetes Mellitus. Qartuppi, 2021. http://dx.doi.org/10.29410/qtp.21.05.
Повний текст джерелаАнотація:
Vivir con un padecimiento crónico degenerativo como la Diabetes Mellitus (DM) implica seguir tratamientos e indicaciones, que podrían suponer un reto para los pacientes y llegar a generar situaciones de estrés. Se sabe que el estrés en pacientes con DM se asocia a un aumento en las cifras de glucosa y a una baja adherencia al tratamiento. Este libro tiene como objetivo ser una guía flexible de un modelo de intervención psicológica en línea atendiendo condiciones contemporáneas. Se desarrolla una propuesta de trabajo breve, con una metodología cognitivo conductual, proponiendo un enfoque práctico que permite al terapeuta tomar diferentes decisiones y seleccionar técnicas ajustadas a las necesidades de cada paciente, adaptando las estrategias y materiales haciendo uso de las Tecnologías de Información y Comunicación (TIC’s).
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Milesi, Verónica, and Pablo Mobili, eds. Fisiología celular: señales y respuestas. Editorial de la Universidad Nacional de La Plata (EDULP), 2019. http://dx.doi.org/10.35537/10915/90432.
Повний текст джерелаАнотація:
En este libro se presentan mecanismos básicos de la fisiología celular que permiten entender cómo responden las células a distintas señales de su entorno. El capítulo 1 introduce al lector en aspectos estructurales y morfológicos básicos de las células animales y los tejidos que estas forman. En el capítulo 2 se analizan los procesos de transporte de sustancias de interés fisiológico (agua, glucosa, gases, iones) a través de la membrana celular, y en el capítulo 3 los fenómenos eléctricos que estos transportes generan. El capítulo 4 está dedicado a la señalización intracelular, que permite a la célula internalizar la información que recibe, y el capítulo 5 presenta distintas maneras en que las células se comunican entre sí. El capítulo 6 integra los conceptos anteriores explicando cómo se llevan a cabo algunas funciones complejas comunes a diferentes organismos pluricelulares desde invertebrados hasta mamífero.
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Juri Moran, Joulia Marianita, Paulina Elizabeth Durán Mora, Estefania Vanessa Arauz Andrade, Yessenia Isabel Sarchi Guayasamin, Alejandra Elizabeth Vasquez Fuel, Cesar Wladimir Reyes Padilla, Pamela Nathaly Pastrano Coronado, Lucia Paola Rodriguez Paz, Martha Elizabeth Aguilar Villagran, and Oscar Andres Toapanta Proaño. Ginecología Obstetricia: Patologías durante el embarazo. Mawil Publicaciones de Ecuador, 2019, 2020. http://dx.doi.org/10.26820/978-9942-826-07-7.
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En Medicina, el área de aplicación de Ginecología, la ciencia de la mujer condensa el estudio de las enfermedades frecuentes y graves, el diagnóstico, detección de los factores de riesgo y establecer mecanismos de prevención, prescribir los tratamientos médicos y quirúrgicos de las enfermedades del sis- tema reproductor femenino, entiéndase, todo lo relacionado con la vagina, las mamas, el útero y los ovarios. Durante el siglo XX, motivado por el crecimiento acelerado del conocimien- to científico y médico, se acrecienta la toma de conciencia del rol que le co- rresponde desempeñar a la medicina en el sector de la salud y la protección de la mujer embarazada. Los problemas del trato genital femenino cuando se asumen como responsabilidad de los ginecólogos, quienes incluyeron dentro del proceso de auscultación, diagnóstico y tratamiento aspectos fisiológicos y endocrinos. Las barreras de la formación académica se fueron difuminando y los ginecó- logos y obstetras comenzaron a estrechar su campo laboral y como resultante se constituyó la Ginecobstetricia. En el marco de estas reflexiones, surge la idea de la presentación de un tex- to titulado Ginecología – Obstetricia, mediante el cual se pretende hacer una contribución real a nivel teórico que permita apoyar a profesionales y estu- diantes en el área de salud humana, básicamente en algunas de las patologías o complicaciones médicas asociadas al embarazo, y tratadas por la especialidad obstétrica, así mismo, se abordan dos temas (1 y 2) de conocimiento general. Cabe indicar que el texto no pretende abordar la vasta información o literatura que sobre los temas se han tratado. El libro ha sido estructurado bajo el perfil de diez (10) temas que discurren estrictamente sobre contenidos específicos, a sa- ber: 1. El parto y sus fases, 2. Pruebas de Bienestar Fetal, 3. Amenaza de Parto Pretérmino, 4. Ruptura Prematura de Membranas, 5. Amenaza de aborto, 6. Desprendimiento de placenta, 7. Infecciones de vías urinarias en embarazadas, 8. Diabetes Gestacional, 9. Hipertension en las embarazadas y 10. Preeclamp- sia y eclampsia En el primer tema, el Parto y sus fases, se precisan diferentes nociones sobre 26 GINECOLOGIA - OBSTETRICIA el proceso y el resultado de parir (dar a luz). A lo largo de la historia ha evolu- cionado el conocimiento de este tema dando como resultado una terminología precisa sobre los diferentes tipos de parto: parto natural, parto normal, parto ins- trumental, parto pretérmino, parto humanizado, etc. Estas nociones obedecen a determinadas circunstancias específicas que lo circunscribe como el uso o no de instrumentos que ayuden al nacimiento de un feto. De manera general, el parto marca el final del embarazo y el nacimiento de la criatura que se engendraba en el útero de la madre. Este proceso por el que la mujer o la hembra de una especie vivípara expulsa el feto y la placenta al final de la gestación consta de tres fases: la fase de dilatación, la de expulsión y la placentaria o de alumbramiento. En el segundo tema titulado Pruebas de Bienestar Fetal, se destaca el desa- rrollo de diferentes pruebas para el control del bienestar fetal. Éstas constitu- yen las técnicas aplicadas a las madres que permiten predecir el posible riesgo fetal o hacer un pronóstico del estado actual del feto, es decir, que tratan de conseguir a través de una valoración del feto de forma sistemática, la identifi- cación de aquellos que están en peligro dentro del útero materno, para así to- mar las medidas apropiadas y prevenir un daño irreversible. Se abordan en este contexto las indicaciones y los métodos (clínicos, biofísicos y bioquímicos más utilizados para el control de bienestar fetal. En el tema tres (3) denominado Amenaza de Parto Pretérmino, el trabajo se centra, en el desarrollo de los siguientes ítems. La Definición de Parto Pretérmi- no, la Definición de amenaza de Parto Pretérmino, la Evaluación del riesgo, la etiología, la Clínica de la Amenaza de Parto Pretérmino, el Diagnóstico precoz de la Amenaza de Parto Pretérmino, la Evaluación de gestantes que acuden a emergencia por signos y síntomas de Amenaza de Parto Pretérmino y el trata- miento. El trabajo parte de la definición de Parto Pretérmino entendido como aquel que ocurre después de la semana 23 y antes de la semana 37 de gestación, para posteriormente, tratar lo relativo a la Amenaza de Parto Pretérmino (APP) definido como el proceso clínico sintomático (Aparición de dinámica uterina regular acompañado de modificaciones cervicales) que puede conducir a un parto pretérmino. Su etiología es compleja y multifactorial, en la que pueden intervenir de forma simultánea factores inflamatorios, isquémicos, inmunológi- cos, mecánicos y hormonales. 27 GINECOLOGIA - OBSTETRICIA Por otro parte, el tema cuatro (4) expone la Ruptura Prematura de Membra- nas, la cual constituye una complicación usual en la práctica obstétrica, esta puede aumentar la incidencia en la morbilidad y mortalidad materna – fetal. Múltiples estudios se están llevando a cabo para poder dilucidar completamente su fisiopatología, lo cual se hace cada vez más necesario para poder aplicar estos conceptos en la práctica clínica, la evidencia actual indica que la Ruptura Prematura de Membrana es un proceso que puede ser afectado por factores: bioquímicos, fisiológicos, patológicos y ambientales. El capítulo cinco (5) comprende la temática sobre la Amenaza de aborto. (AA) que es la complicación más común durante el embarazo, se define como el sangrado transvaginal antes de las 20 semanas de gestación (SDG) gestación o con un feto menor de 500g, con o sin contracciones uterinas, sin dilatación cervical y sin expulsión de productos de la concepción”. Es decir, se presenta hemorragia de origen intrauterino antes de la vigésima semana completa de ges- tación, con o sin contracciones uterinas, sin dilatación cervical y sin expulsión de los productos de la concepción. Los síntomas abarcan amenorrea secundaria, presencia de vitalidad fetal y cólica abdominales con o sin sangrado vaginal entre otros. Para el diagnóstico se puede hacer una ecografía abdominal o va- ginal, examen pélvico y de laboratorio. En un principio el tratamiento consiste en recomendar reposo en cama y reposo pélvico. La identificación de factores de riesgo, el Ultrasonido obstétrico y la medición de marcadores bioquímicos son de gran importancia para realizar un diagnóstico y establecer un pronóstico oportuno. Estos aspectos y otros relacionados con el tema como son: la clínica, el protocolo a seguir, el tratamiento y la prevención, son tratados en este capí- tulo. El tema Desprendimiento de placenta es desarrollado a lo largo del tema seis (6). Su contenido aborda los aspectos importes como los factores de riesgo, etiología, síntomas y signos, diagnóstico y tratamiento de esta complicación cuyo proceso se caracteriza por el desprendimiento total o parcial, antes del parto, de una placenta que esta insertada en su sitio normal. Este hecho que puede traer grandes consecuencias para el feto y para la madre, puede ocurrir en cualquier momento del embarazo. Los desprendimientos producidos antes de las 20 semanas, por su evolución, deberán ser tratados como abortos. Los que tienen lugar después de la semana 20 de gestación y antes del alumbramiento constituyen el cuadro conocido como desprendimiento prematuro de la placenta normalmente insertada. (abrptio plantae o accidente de Baudelocque). El pro- ceso ha tenido una variedad de denominaciones a lo largo del tiempo y son consecuencia de la diversidad de cuadros clínicos que pueden producirse, sien- do las más empleadas en la actualidad: abruptio placentae, ablatio placentae, desprendimiento prematuro de placenta normalmente inserta (DPPNI), junto con el término abreviado desprendimiento prematuro de placenta (DPP). Para hablar de otra importante complicación que aqueja a la gestante y su bebe por nacer se expone en el tema (7) relacionado con las Infecciones de vías urinarias en embarazadas. Los particulares cambios morfológicos y funcio- nales que se producen en el tracto urinario de la gestante hacen que la infec- ción del tracto urinario (ITU) sea la segunda patología médica más frecuente del embarazo, por detrás de la anemia. Las 3 entidades de mayor repercusión son: Bacteriuria asintomática (BA) (2-11%), cuya detección y tratamiento son fundamentales durante la gestación, pues se asocia a prematuridad, bajo peso y elevado riesgo de progresión a pielonefritis aguda (PA) y sepsis; la Cistitis aguda (CA) (1,5%) y la Pielonefritis aguda (1-2%), principal causa de ingreso no obstétrico en la gestante, que en el 10 al 20% de los casos supone alguna complicación grave que pone en riesgo la vida materna y la fetal. La Diabetes Gestacional se ubica y desarrolla en el tema ocho (8). Este tipo de diabetes que aparece o se diagnostica durante el embarazo ha aumentado su prevalencia y cobrado gran relevancia epidemiológica en los últimos años. La Diabetes Gestacional (DG) o Diabetes Mellitius Gestacional (DMG) se carac- teriza por una secreción de insulina insuficiente para compensar la resistencia a la hormona, propia del embarazo. Después del parto, los niveles de glucosa sanguínea suelen normalizarse; sin embargo, algunas mujeres desarrollan DM tipo 2 y se asocia con complicaciones graves en la madre y el hijo, incluso años después del nacimiento. La Hipertensión en las Embarazadas, tema tan tratado y controvertido en los últimos años por su significación a nivel de que es la complicación médica 29 GINECOLOGIA - OBSTETRICIA más frecuente de la gestación y ocurre según estudios comprobados en el 7% a 10% de los embarazos y constituye una causa importante de morbimortalidad materna y perinatal. De manera clásica, la HTA en el embarazo ha sido definida como el incremento, durante la gestación, de la presión arterial sistólica (PAS) en 30 mmHg o más y/o la presión arterial diastólica (PAD) en 15 mmHg o más comparado con el promedio de valores previos a la 20va. semana de gestación. Cuando no se conocen valores previos, una lectura de 140/90 mmHg o mayor es considerada como anormal. El tema desarrollado abarca una visión general sobre algunos aspectos relativos a la definición y su clasificación, los factores predisponentes, sintomatología, diagnóstico, tratamiento, etc. Por último, el tema 10 aborda dos alteraciones íntimamente ligadas a la hi- pertensión arterial en el embarazo: la preeclampsia y la eclampsia. Éstas son en ocasiones tratadas como componentes de un mismo síndrome ya que la pree- clampsia es la hipertensión de reciente comienzo con proteinuria después de las 20 semanas de gestación y la eclampsia es la presencia de convulsiones genera- lizadas inexplicables en pacientes con preeclampsia.
Частини книг з теми "Glucose ester"
1
Takaichi, S., K. Tsuji, S. Hanada, K. Matsuura, and K. Shimada. "A Novel Carotenoid Glucoside Ester in Green Filamentous Bacteria." In Photosynthesis: from Light to Biosphere, 3091–94. Dordrecht: Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-009-0173-5_725.
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2
Taber, Douglass. "The Paquette Synthesis of Fomannosin." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0096.
Повний текст джерелаАнотація:
The compact sesquiterpene ( + )-fomannosin 3, isolated from the pathogenic fungus Fomes annonsus, presents an interesting set of challenges for the organic synthesis chemist, ranging from the strained cyclobutene to the easily epimerized cyclopentanone. In the synthesis of 3 developed (J. Org. Chem . 2008, 73, 4548) by Leo A. Paquette of Ohio State University, the cyclopentane was constructed by ring-closing metathesis of 1. The real challenge of the synthesis was the enantiospecific preparation of 1 from D-glucose. The starting point for the preparation of 1 was the glucose derivative 4. Selective acetonide hydrolysis followed by oxidative cleavage gave the ester 5, which on base treatment followed by hydrogenation delivered the endo ester 6. Condensation of the enolate of 6 with formaldehyde proceeded with high diastereoselectivity, to give, after protection, the ester 7. Conversion of the ester to the vinyl group, exposure to methanolic acid and ether formation completed the preparation of 9. The construction of the cyclobutane of 1 was effected by an interesting application of the Negishi reagent (Cp2ZrCl2/2 x BuLi). Complexation of Cp2Zr with the alkene followed by elimination generated an allylic organometallic 11, which added to the released aldehyde to give the cyclobutanes 12 and 13 in a 2.4:1 diastereomeric ratio. Homologation of the aldehyde 13 and subsequent oxidation were straightforward, but subsequent methylenation of the hindered carbonyl was not. At last, it was found that Peterson olefination worked well. Metathesis then delivered the cyclopentene 2. The last carbons of the skeleton were added by intramolecular aldol cyclization of the thioester 16. The seemingly simple task of converting the alkene of 17 into a ketone proved challenging. Eventually, dihydroxylation followed by oxidation, and then SmI2 reduction, completed the transformation. This still left the challenge of controlling the cyclopentane stereogenic center. Remarkably, dehydration and epimerization led to (+)-Fomannosin 3 as a single dominant diastereomer.
3
Pershadsingh, Harrihar A., Debra L. Shade, and Jay M. McDonald. "STIMULATION OF GLUCOSE TRANSPORT BY INSULIN, VANADATE, CONCANAVALIN A, HYDROGEN PEROXIDE, AND PHORBOL ESTER OCCUR BY A CALCIUM-DEPENDENT MECHANISM." In Calcium-Binding Proteins in Health and Disease, 201–3. Elsevier, 1987. http://dx.doi.org/10.1016/b978-0-12-521040-9.50039-5.
Повний текст джерела
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Akinyinka Akinwumi, Kazeeem, Oluwole Olusoji Eleyowo, and Omolara Omowunmi Oladipo. "A Review on the Ethnobotanical Uses, Phytochemistry and Pharmacology Effect of Luffa cylindrica." In Pharmacognosy - Medicinal Plants [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98405.
Повний текст джерелаАнотація:
Luffa cylindrica, popularly known as sponge gourd is a tropic and sub-tropical fibrous plant with fruits containing black seeds. The fruit is consumed by humans as a vegetable in many parts of Asia, while different parts of the plant are used for cosmetics and as medicine in many parts of the globe. The plant has been used in the treatment of many ailments including nose cancer, snake venom, wound healing, edema, enterobiasis, filaria, whooping cough, stomach upset, stomach pain and malaria. Many health-promoting compounds such as flavonoids (apigenin-7- glucuronide luteolin-7-O-β-D-glucuronide methyl ester, -O-feruloyl-β-D-glucose, luteolin-7-O-β-D-glucuronide methyl ester), phenolics acids (p-Coumaric, gallic, caffeic, chlorogenic), triterpenoids (oleanolic acid and echinocystic acid), saponins (Lucyoside A-M), tannins (catechin), ribosome-inactivating proteins (α- luffin), carotenoids (9 -cis neoxanthin, all-trans-lutein, all-trans-β-carotene), chlorophylls (chlorophyll a and b, pheophytin), cucurbitacin B and gypsogenin have been detected or isolated from different parts of the plants. Extracts of the plant and isolated compounds have wide spectrum pharmacological activities and have been shown to possess antiemetic, antidiabetic, antiviral, wound healing, anticancer, antipyretic, anti-inflammatory, antifungal, anti-bacteria, anthelmintic, hypoglycemic and antihyperglycemic, anti-inflammatory, antioxidant activity, and hepato-protective effects in animal models. However, further information is needed on its safety and mechanisms of action. The present article is an updated review of the ethnobotanical uses, pharmacological actions, phytochemistry, safety, and future application of Luffa cylindrica in translational medicine.
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"Digitoxigenin β-D-Glucoside Melonyl Ester." In Spectroscopic Data of Steroid Glycosides: Cardenolides and Pregnanes, 2300. Boston, MA: Springer US, 2006. http://dx.doi.org/10.1007/978-0-387-39576-0_239.
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Goodger, Jason Q. D., and Ian E. Woodrow. "Oleuropeic and Menthiafolic Acid Glucose Esters from Plants." In Studies in Natural Products Chemistry, 427–52. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-444-59603-1.00012-6.
Повний текст джерела
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Dalton, David R. "Working in the Dark." In The Chemistry of Wine. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190687199.003.0019.
Повний текст джерелаАнотація:
Three turns of the Calvin cycle (Figure 11.1), allow the conversion of three (3) equivalents of carbon dioxide (CO2) (i.e., 3 C1 units) along with three (3) equivalents of the five-carbon carbohydrate derivative, ribulose-1,5-bisphosphate (i.e., 3 C5 units) to yield three (3) not yet isolated six-carbon adducts, 2-carboxy-3-ketoribitol-1,5-bisphosphate (3 C1 + 3 C5 = 3 C6) to form. The three (3) C6 species then undergo fragmentation to yield six (6) equivalents of the three (3) carbon dihydroxy monocarboxylate, 3-phosphoglycerate (i.e., 3 C6 = 6 C3). A cartoon representation of this process is shown in Scheme 11.1 for one of the three CO2 units. Of the six (6) three-carbon unit equivalents, five (5) are used to regenerate three (3) equiv¬alents of ribulose-1,5-bisphosphate (i.e., 5 C3 = 3 C5), while the sixth three- carbon fragment is now available to combine with another to make a six (6) carbon sugar (2 C3 = 1 C6) such as glucose (C6H12O6) (Figure 11.2). Additionally, as shown in Figure 11.3, 3-phosphoglycerate can be used to make other small compound building blocks such as glyceric acid, lactic acid, pyruvic acid and even acetic acid (after decarboxylation). Ribulose- 1,5-bisphosphate (often abbreviated as RuBP), using the enzyme ribulose- 1,5- bisphosphate carboxylase (EC 4.1.1.39, carboxydismutase, rubisco), catalyzes the Mg2+- dependent conversion of the 1,5- bisphosphate ester of the carbohydrate ribulose with carbon dioxide (CO2) to produce two (2) equivalents of 3- phosphoglycerate (PGA). As shown in the Schemes 11.1 and 11.2. A hypothetical the six carbon intermediate, 2- carboxy- 3- ketoribitol- 1,5- bisphosphate, is often written. It is important to keep in mind that we want the 3- phosphoglycerate for purposes of construction of other important compounds. But, as noted above, three turns of the cycle are necessary to produce six (6) equivalents of 3- phosphoglycerate, and five (5) of them are reused in making the three (3) ribulose- 1,5- bisphosphates necessary to turn the cycle three (3) times.
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Juan, Carlos G., Benjamin Potelon, Cédric Quendo, Héctor García-Martínez, Ernesto Ávila-Navarro, Enrique Bronchalo, and José M. Sabater-Navarro. "Sensor de glucosa biocompatible basado en Qu con resonador de microondas en microstrip invertida." In XLIII Jornadas de Automática: libro de actas: 7, 8 y 9 de septiembre de 2022, Logroño (La Rioja), 94–101. 2022nd ed. Servizo de Publicacións da UDC, 2022. http://dx.doi.org/10.17979/spudc.9788497498418.0094.
Повний текст джерелаАнотація:
En este trabajo se muestra un sensor de glucosa basado en los cambios del factor de calidad sin carga (Qu) de un resonador de microondas. La implementación se ha realizado con fabricación aditiva empleando un material biocompatible. Se ha diseñado una estructura en configuración de línea microstrip invertida para aumentar la sensibilidad. El artículo muestra el interés de la medida basada en Qu tanto desde el punto de vista analítico como desde el experimental. El sensor final trabaja a 4.62 GHz con un Qu base de 27.87. Los resultados han mostrado un aumento de la sensibilidad con respecto a otros trabajos, lo que ha permitido realizar la medida de concentraciones de glucosa habituales en el contexto de la diabetes.
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Andresen, Otto, and Ole Kirk. "Fatty acid esters of ethyl glucoside, a unique class of surfactants." In Progress in Biotechnology, 343–49. Elsevier, 1995. http://dx.doi.org/10.1016/s0921-0423(06)80115-2.
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Kovalenko, Galina, and Larisa Perminova. "Heterogeneous Biocatalysts for the Final Stages of Deep Processing of Renewable Resources into Valuable Products." In Molecular Biotechnology [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.89411.
Повний текст джерелаАнотація:
Heterogeneous biocatalysis is a part of biotechnology and it has commercial potential for industrial implementation, in particular the final stages of deep processing of renewable raw materials. The commercially attractive heterogeneous biocatalysts are prepared by immobilizing practically valuable enzymatic active substances onto solid inorganic supports. Heterogeneous biocatalytic processes of the target conversion of substrate into valuable market product are carried out in periodic or continuous modes using traditional batch and packed-bed reactors, as well as novel types of vortex reactors in accordance with the principles of green chemistry. Heterogeneous biocatalysts for the final stages of deep processing of vegetable raw materials such as starch and oils are described here. One of the biocatalysts is glucoamylase immobilized by adsorption on mesoporous carbon support Sibunit™ type. This glucoamylase-active biocatalyst is used at the stage of starch saccharification, i.e., hydrolysis of dextrin to treacle and glucose syrups used in food and confectionary industries. The second of the biocatalysts is recombinant T. lanuginosus lipase immobilized on mesoporous silica KSK™ type and macroporous carbon aerogel. These lipase-active biocatalysts can effectively compete with traditional organic synthesis catalysts, and they are used in low-temperature processes carried out in unconventional anhydrous media such as interesterification of vegetable oils’ triglycerides with ethyl acetate for producing ethyl esters of fatty acids (biodiesel and vitamin F) and esterification of fatty acids with aliphatic alcohols for synthesis of various esters used as fragrances, flavorings, odors, emollients, and nonionic surfactants in perfume and cosmetics industries. The prepared heterogeneous biocatalysts due to their high enzymatic activity and operational stability are promising for practical implementation.
Тези доповідей конференцій з теми "Glucose ester"
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Zhong, J. L., M. Watanabe, K. Kadowaki, T. Mori, M. Yamashiro, T. Kashiwagi, T. Tanaka, et al. "Spectroscopic characterization at THz frequencies of glucose-based biomaterials: paramylon, paramylon-ester and cellulose." In 2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz). IEEE, 2019. http://dx.doi.org/10.1109/irmmw-thz.2019.8874487.
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Zhou, Daiyu, Liming Lian, Zangyuan Wu, Gengping Yan, Wei Zhou, Guangqiang Shao, Haihang Sun, et al. "Optimization Design and Evaluation of Improved Miscible Assistants for CO2 Flooding and the Application in Pilot in L Reservoir." In International Petroleum Technology Conference. IPTC, 2022. http://dx.doi.org/10.2523/iptc-22244-ms.
Повний текст джерелаАнотація:
Abstract This paper provide several improved miscible assistants, trying to mitigate the problem that CO2 miscible flooding is difficult to achieve in reservoirs because of the high miscible pressures, which leads to a lower recovery up to expectations. These miscible assistants could be easily mixed with crude oil by adding into CO2 and reduce the interfacial tension to drive down the minimum miscible pressure (MMP) in order to enhance sweep efficiency. Some efforts have been made to improve this situation. The effective method is to draw the experiences from structure characteristics of surfactants applied in micro emulsion of CO2-water systems. Amphiphilic organic assistants were designed to synthetize with fluoro-alkane chains and non-fluoro-OAc chains as the CO2-philic ends, as well as alkane structure as the lipophilic ends. The minimization of MMP of CO2 miscible processing assistants has been analyzed and optimized by surface tension testing in CO2-kerosene system and CO2-crude oil system. The crude oil was obtained from field test pilot in L Reservoir. The results of interfacial tension tests show that per-acetylated glucose dodecyl ester molecules have the ability to lower the interfacial tension most in these five kinds of new miscible processing assistants in two categories. Citric acid triisopropyl ester molecules take the second place, and others almost make no difference. The probable reason is that kerosene is mainly composed of C12 and lack of heavy components, which cause a weak interaction between independent hydroxyl of citric acid and tartaric acid assistant and hydrogen bond of kerosene. The results of interfacial tension tests show that all these miscible assistants possess good effects on minimizing the interfacial tension of the CO2-crudes system, and could also definitely reduce the MMP. Among these, per-acetylated glucose dodecyl ester molecules and citric acid isopropyl ester molecules perform most excellent, and could decrease the MMP of CO2 flooding by 27.5%. The assistants have been implemented in the CO2 flooding plan of L Reservoir with 4 gas injectors and 15 producers. After 15 years’ development simulation, cumulated oil production will reach 3.4 MMbbl with recovery increasing from 41.6% (only CO2 flooding) to 46.6%. Injection test shows that 1400 tons CO2 has been injected with 3800 bbl oil produced. The improved miscible assistants provided perform as well as other existing assistants in reducing interfacial tension and enhancing sweep efficiency in CO2 flooding. Compared with assistants of light hydrocarbon, these assistants require a little quantity to improve the miscible flooding, which could break the economic limits. Compared with the traditional fluoride assistants, these assistants are quite different in molecular structure and could cause little pollution and have been applied in field test.
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Shaikh, Saame (Raz), Anandita Pal, and Ian Carroll. "Eicosapentaenoic acid ethyl esters prevent obesity-driven impairments to glucose homeostasis through the biosynthesis of downstream hydroxylated metabolites." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/colx6433.
Повний текст джерелаАнотація:
There is considerable debate on the clinical utility of the long n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) for preventing dysregulation of obesity-driven glucose homeostasis. Herein, we first show that administration of ethyl esters of EPA, but not DHA, to C57BL/6J male mice improves hyperglycemia, hyperinsulinemia, and glucose tolerance. Mechanistically, we demonstrate that EPA reverses the obesity-driven decrease in the concentration of white adipose tissue and liver 18-hydroxyeicosapentaenoic acid (18-HEPE), the precursor for resolvin E1 (RvE1). A combination of add-back and receptor knockout experiments reveal that RvE1 is specifically driving the improvement in hyperinsulinemia and hyperglycemia through the receptor known as ERV1/ChemR23 by controlling pathways related to hepatic glucose metabolism and inflammation. Next, we show that EPA’s effects are distinct in female mice as EPA administration leads to improvements in body weight, hyperinsulinemia and hyperglycemia but not glucose tolerance. In this case, EPA exerts its effects through a mechanism potentially mediated by 8-HEPE and upregulation of key intestinal microbes. Finally, we present translation data showing that glucose levels in humans with obesity are inversely related to EPA but not DHA in a sex-specific manner. Furthermore, data from our pilot clinical trial demonstrate that an 18-HEPE-enriched marine oil supplement increases RvE1 levels by 3-fold in humans with obesity. Taken together, these results provide clarity to the field by suggesting that EPA but not DHA ethyl esters can prevent glucose dysregulation in a sex-specific manner through distinct mechanisms mediated by downstream hydroxylated metabolites.
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Ibrahim, A., E. Onyike, A. J. Nok, A. Muhammad, and I. A. Umar. "2, 3, 4, 5-Tetrahydroxy-Cyclohexane Ester Glucoside Isolated from Combretum Micranthum Methanol Extract is a Potent Anti-Diabetic." In the 2018 7th International Conference. New York, New York, USA: ACM Press, 2018. http://dx.doi.org/10.1145/3239264.3239265.
Повний текст джерела
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Oliveira, Pedro, Italo Araújo, Evilasio Junior, Paulo Duarte, Ismayle S. Santos, Rossana M. C. Andrade, Ivana Cristina H. C. Barreto, and Luiz Odorico M. Andrade. "Dorsal: Ferramenta para Geração de Modelos de Dados para Aplicações voltadas a Saúde e Cuidado de Idosos." In Anais Estendidos do Simpósio Brasileiro de Computação Aplicada à Saúde. Sociedade Brasileira de Computação (SBC), 2020. http://dx.doi.org/10.5753/sbcas.2020.11549.
Повний текст джерелаАнотація:
O envelhecimento da população aliado a um maior interesse por saúde e bem-estar têm motivado o desenvolvimento de aplicações web e mobile para prover longevidade com maior qualidade de vida. Contudo, modelar dados para sistemas de saúde do idoso é uma tarefa complexa e, então, para auxiliar desenvolvedores a lidar com essa dificuldade, em um trabalho anterior do nosso grupo de pesquisa, foi desenvolvida uma taxonomia de dados para 7 tipos de sistemas de saúde do idoso. Essa taxonomia é composta por 21 categorias e 87 características que organizam os dados que devem ser manipulados por esses sistemas. Por exemplo, a categoria “Controle de Glicose” (Glucose Control) possui data e glicemia como duas características. Entretanto, a combinação entre os tipos de aplicação, categorias e características gera um grande número de possibilidades, dificultando a utilização desta taxonomia. Sendo assim, a ferramenta Dorsal, proposta neste artigo, tem como objetivo gerar modelos de dados em Java ou Javascript a partir desta taxonomia para reduzir o esforço de desenvolvimento de aplicações para saúde do idoso.
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Kulikov, Denis, Ruzaliya Ulanova, and Valentina Kolpakova. "COMPREHENSIVE BIOTECHNOLOGICAL APPROACH TO PROCESSING OF PEA FLOUR FOR FOOD AND FODDER PURPOSES." In GEOLINKS Conference Proceedings. Saima Consult Ltd, 2021. http://dx.doi.org/10.32008/geolinks2021/b1/v3/06.
Повний текст джерелаАнотація:
Investigations were carried out to optimize the growth parameters of the symbiosis of cultures of the yeast Saccharomyces cerevisiae 121 and the fungus Geotrichum candidum 977 on whey waters formed from pea flour as a secondary product in the production of protein concentrates after precipitation of proteins at the isoelectric point. The whey remaining after protein precipitation is bioconverted at optimal parameters of crop growth (pH of the medium, amount of inoculum, temperature) with the formation of microbial plant concentrate (MPC) for feed purposes. Serum cultures assimilated stachyose, glucose, maltose, arabinose, and other pentoses. The mass fraction of protein in the concentrate was 57.90-61.68 % of DS. The composition of MPC obtained from biomass is balanced in essential amino acids with a speed of 107-226 %. The fatty acid composition is represented by 97 % fatty acids and 3 % - esters, aldehydes, ketones with the properties of fragrances, photo stabilizers, odor fixers, preservatives and other compounds. The ratio of the sum of saturated and unsaturated acids is 1:3, the content of cis-isomers is 91.1 %, trans-isomers are 5.1 %, omega-6 fatty acids are 19.73 %. The quality and safety indicators indicated that it is promising for use in the diet of animals.
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Nascimento, Karoline Silva do, and Rosane Cristina Pinheiro Souza. "TESTE DE GLICOSE A PARTIR DO REATIVO DE BENEDICT." In II Congresso Brasileiro de Bioquímica Humana On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/conbraqui/1.
Повний текст джерелаАнотація:
Introdução: Diabetes é uma doença causada pela produção insuficiente ou má absorção de insulina, um hormônio que regula o açúcar no sangue e fornece energia ao corpo. A insulina é um hormônio que tem a função de quebrar as moléculas de glicose (açúcar), convertendo-a em energia para manter as células do nosso corpo. O teste de glicose é geralmente utilizado para detectar açúcares redutores (monossacarídeos, como a glucose, e dissacarídeos, como a maltose e a lactose) e aldeídos. A solução de Fehling é constituída por uma solução de sulfato de cobre(II) e por uma solução alcalina de tartrato de sódio 2,3-di hidroxibutanodiato. Objetivo: Identificar através do Teste com reagente de Benedict, qual a possível taxa de glicose que será encontrada na urina do paciente x, conforme a coloração formada. Material e métodos: Para o procedimento foram utilizados a lamparina Álcool, tubo de ensaio, pregador, 2,5 ml de reativo de Benedict, 4 gotas de urina, pipetador, pipeta de 5ml, e pipeta pauster, Foram medidos na pipeta 2,5 ml de reativo de Benedict, e transferido para um tubo de ensaio e em seguida este tubo com o reagente foi levado para ser aquecido na lamparina álcool assim que o mesmo atingiu fervura, observando que, o reativo e colocado em nesse estado para verificar se não há contaminação. Então, adiciona se com a pipeta pauster, 4 gotas de urina de um paciente x, e retorna para ser aquecido e continua agitando para que fique em ebulição por 1 minuto. Resultados: É observado a mudança de coloração que vai indicar a taxa de glicose que há nessa urina. O reagente de Benedict é usado geralmente no lugar da solução de Fehling para detectar excesso de açúcar na urina e detectar uma possível diabete. A fervura verifica-se uma alteração na cor original do reagente; uma cor esverdeada indica a presença de pouco açúcar e uma cor precipitado vermelho indica altos índices de açúcar, no caso do estudo foi identificado uma cor esverdeada. Conclusão: conclui-se que o teste de glicose é de essencial importância para acompanhamento de níveis glicêmicos e que através dos resultados no teste de reagente de Benedict o paciente x tem traços de glicose no sangue.
Звіти організацій з теми "Glucose ester"
1
Gao, Hui, Chen Gong, Shi-chun Shen, Jia-ying Zhao, Dou-dou Xu, Fang-biao Tao, Yang Wang, and Xiao-chen Fan. A systematic review on the associations between prenatal phthalate exposure and childhood glycolipid metabolism and blood pressure: evidence from epidemiological studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0111.
Повний текст джерелаАнотація:
Review question / Objective: The present systematic review was performed to obtain a summary of epidemiological evidence on the relationships of in utero exposure to phthalates with childhood glycolipid metabolism and blood pressure. Condition being studied: Childhood cardiovascular risk factors including blood pressure, lipid profile (e.g., triglycerides, total cholesterol, HDL−C, LDL−C) and glucose metabolism (e.g., insulin, insulin resistance, insulin sensitivity, glucose) were the interested outcomes. Eligibility criteria: In brief, epidemiological studies including cohort study, case-control study and cross-sectional survey were screened. Studies regarding relationships between human exposure to organophosphate esters and neurotoxicity were possible eligible for the present systematic review. The adverse neurodevelopmental outcomes included development of cognition, behavior, motor, brain change, emotion, etc. Studies that did not meet the above criteria were not included in this systematic review.