Добірка наукової літератури з теми "Gene ontology enrichment"
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Статті в журналах з теми "Gene ontology enrichment"
Shameer, Khader, Mahantesha Bn Naika, Oommen K. Mathew, and Ramanathan Sowdhamini. "POEAS: Automated Plant Phenomic Analysis Using Plant Ontology." Bioinformatics and Biology Insights 8 (January 2014): BBI.S19057. http://dx.doi.org/10.4137/bbi.s19057.
Повний текст джерелаDalmer, Timothy R. A., and Robin D. Clugston. "Gene ontology enrichment analysis of congenital diaphragmatic hernia-associated genes." Pediatric Research 85, no. 1 (September 25, 2018): 13–19. http://dx.doi.org/10.1038/s41390-018-0192-8.
Повний текст джерелаJupiter, Daniel, Jessica Şahutoğlu, and Vincent VanBuren. "TreeHugger: A New Test for Enrichment of Gene Ontology Terms." INFORMS Journal on Computing 22, no. 2 (May 2010): 210–21. http://dx.doi.org/10.1287/ijoc.1090.0356.
Повний текст джерелаRaza, Khalid. "Reconstruction, Topological and Gene Ontology Enrichment Analysis of Cancerous Gene Regulatory Network Modules." Current Bioinformatics 11, no. 2 (April 1, 2016): 243–58. http://dx.doi.org/10.2174/1574893611666160115212806.
Повний текст джерелаZheng, Qi, and Xiu-Jie Wang. "GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis." Nucleic Acids Research 36, suppl_2 (May 16, 2008): W358—W363. http://dx.doi.org/10.1093/nar/gkn276.
Повний текст джерелаDalmer, Timothy R. A., and Robin D. Clugston. "Correction: Gene ontology enrichment analysis of congenital diaphragmatic hernia-associated genes." Pediatric Research 86, no. 5 (August 14, 2019): 676. http://dx.doi.org/10.1038/s41390-019-0536-z.
Повний текст джерелаMi, Gu, Yanming Di, Sarah Emerson, Jason S. Cumbie, and Jeff H. Chang. "Length Bias Correction in Gene Ontology Enrichment Analysis Using Logistic Regression." PLoS ONE 7, no. 10 (October 2, 2012): e46128. http://dx.doi.org/10.1371/journal.pone.0046128.
Повний текст джерелаHinderer, Eugene W., Robert M. Flight, Rashmi Dubey, James N. MacLeod, and Hunter N. B. Moseley. "Advances in gene ontology utilization improve statistical power of annotation enrichment." PLOS ONE 14, no. 8 (August 15, 2019): e0220728. http://dx.doi.org/10.1371/journal.pone.0220728.
Повний текст джерелаShah, N. H., and N. V. Fedoroff. "CLENCH: a program for calculating Cluster ENriCHment using the Gene Ontology." Bioinformatics 20, no. 7 (February 5, 2004): 1196–97. http://dx.doi.org/10.1093/bioinformatics/bth056.
Повний текст джерелаChittenden, Thomas W., Eleanor A. Howe, Jennifer M. Taylor, Jessica C. Mar, Martin J. Aryee, Harold Gómez, Razvan Sultana, et al. "nEASE: a method for gene ontology subclassification of high-throughput gene expression data." Bioinformatics 28, no. 5 (January 13, 2012): 726–28. http://dx.doi.org/10.1093/bioinformatics/bts011.
Повний текст джерелаДисертації з теми "Gene ontology enrichment"
Wimberley, James. "De novo Sequencing and Analysis of Salvia hispanica Transcriptome and Identification of Genes Involved in the Biosynthesis of Secondary Metabolites." Chapman University Digital Commons, 2019. https://digitalcommons.chapman.edu/cads_theses/5.
Повний текст джерелаHe, Xin. "A semi-automated framework for the analytical use of gene-centric data with biological ontologies." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/25505.
Повний текст джерелаHinderer, Eugene Waverly III. "COMPUTATIONAL TOOLS FOR THE DYNAMIC CATEGORIZATION AND AUGMENTED UTILIZATION OF THE GENE ONTOLOGY." UKnowledge, 2019. https://uknowledge.uky.edu/biochem_etds/43.
Повний текст джерелаHassan, Aamir Ul. "Integration of Genome Scale Data for Identifying New Biomarkers in Colon Cancer: Integrated Analysis of Transcriptomics and Epigenomics Data from High Throughput Technologies in Order to Identifying New Biomarkers Genes for Personalised Targeted Therapies for Patients Suffering from Colon Cancer." Thesis, University of Bradford, 2017. http://hdl.handle.net/10454/17419.
Повний текст джерелаGroß, Anika. "Evolution von ontologiebasierten Mappings in den Lebenswissenschaften." Doctoral thesis, Universitätsbibliothek Leipzig, 2014. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-136766.
Повний текст джерелаIn the life sciences, there is an increasing number of heterogeneous data sources that need to be integrated and combined in comprehensive analysis tasks. Often ontologies and other structured vocabularies are used to provide a formal representation of knowledge and to facilitate data exchange between different applications. Ontologies are used in different domains like molecular biology or chemistry. One of their most important applications is the annotation of real-world objects like genes or publications. Since different ontologies can contain overlapping knowledge it is necessary to determine mappings between them (ontology mappings). A manual mapping creation can be very time-consuming or even infeasible such that (semi-) automatic ontology matching methods are typically applied. Ontologies are not static but underlie continuous modifications due to new research insights and changing user requirements. The evolution of ontologies can have impact on dependent data like annotation or ontology mappings. This thesis presents novel methods and algorithms to deal with the evolution of ontology-based mappings. Thereby the generic infrastructure GOMMA is used and extended to manage and analyze the evolution of ontologies and mappings. First, a comparative evolution analysis for ontologies and mappings from three life science domains shows heavy changes in ontologies and mappings as well as an impact of ontology changes on the mappings. Hence, existing ontology mappings can become invalid and need to be migrated to current ontology versions. Thereby an expensive redetermination of the mappings should be avoided. This thesis introduces two generic algorithms to (semi-) automatically adapt ontology mappings: (1) a composition-based adaptation relies on the principle of mapping composition, and (2) a diff-based adaptation algorithm allows for individually handling change operations to update mappings. Both approaches reuse unaffected mapping parts, and adapt only affected parts of the mappings. An evaluation for very large biomedical ontologies and mappings shows that both approaches produce ontology mappings of high quality. Similarly, ontology changes may also affect ontology-based annotation mappings. The thesis introduces a generic evaluation approach to assess the quality of annotation mappings based on their evolution. Different quality measures allow for the identification of reliable annotations, e.g., based on their stability or provenance information. A comprehensive analysis of large annotation data sources shows numerous instabilities, e.g., due to the temporary absence of annotations. Such modifications may influence results of dependent applications such as functional enrichment analyses that describe experimental data in terms of ontological groupings. The question arises to what degree ontology and annotation changes may affect such analyses. Based on different stability measures the evaluation assesses change intensities of application results and gives insights whether users need to expect significant changes of their analysis results. Moreover, GOMMA is extended by large-scale ontology matching techniques. Such techniques are useful, a.o., to match new concepts during ontology mapping adaptation. Many existing match systems do not scale for aligning very large ontologies, e.g., from the life science domain. One efficient composition-based approach indirectly computes ontology mappings by reusing and combining existing mappings to intermediate ontologies. Intermediate ontologies can contain useful background knowledge such that the mapping quality can be improved compared to a direct match approach. Moreover, the thesis introduces general strategies for matching ontologies in parallel using several computing nodes. A size-based partitioning of the input ontologies enables good load balancing and scalability since smaller match tasks can be processed in parallel. The evaluation of the Ontology Alignment Evaluation Initiative (OAEI) compares GOMMA and other systems in terms of matching ontologies from different domains. Using the parallel and composition-based matching, GOMMA can achieve very good results w.r.t. efficiency and effectiveness, especially for ontologies from the life science domain
Vashisht, S. "COMPUTATIONAL APPROACHES IN THE ESTIMATION AND ANALYSIS OF TRANSCRIPTS DIFFERENTIAL EXPRESSION AND SPLICING: APPLICATION TO SPINAL MUSCULAR ATROPHY." Doctoral thesis, Università degli Studi di Milano, 2017. http://hdl.handle.net/2434/470076.
Повний текст джерелаFruzangohar, Mario. "Biomedical literature mining." Thesis, 2014. http://hdl.handle.net/2440/85201.
Повний текст джерелаThesis (Ph.D.) -- University of Adelaide, School of Molecular and Biomedical Science, 2014
Groß, Anika. "Evolution von ontologiebasierten Mappings in den Lebenswissenschaften." Doctoral thesis, 2013. https://ul.qucosa.de/id/qucosa%3A12314.
Повний текст джерелаIn the life sciences, there is an increasing number of heterogeneous data sources that need to be integrated and combined in comprehensive analysis tasks. Often ontologies and other structured vocabularies are used to provide a formal representation of knowledge and to facilitate data exchange between different applications. Ontologies are used in different domains like molecular biology or chemistry. One of their most important applications is the annotation of real-world objects like genes or publications. Since different ontologies can contain overlapping knowledge it is necessary to determine mappings between them (ontology mappings). A manual mapping creation can be very time-consuming or even infeasible such that (semi-) automatic ontology matching methods are typically applied. Ontologies are not static but underlie continuous modifications due to new research insights and changing user requirements. The evolution of ontologies can have impact on dependent data like annotation or ontology mappings. This thesis presents novel methods and algorithms to deal with the evolution of ontology-based mappings. Thereby the generic infrastructure GOMMA is used and extended to manage and analyze the evolution of ontologies and mappings. First, a comparative evolution analysis for ontologies and mappings from three life science domains shows heavy changes in ontologies and mappings as well as an impact of ontology changes on the mappings. Hence, existing ontology mappings can become invalid and need to be migrated to current ontology versions. Thereby an expensive redetermination of the mappings should be avoided. This thesis introduces two generic algorithms to (semi-) automatically adapt ontology mappings: (1) a composition-based adaptation relies on the principle of mapping composition, and (2) a diff-based adaptation algorithm allows for individually handling change operations to update mappings. Both approaches reuse unaffected mapping parts, and adapt only affected parts of the mappings. An evaluation for very large biomedical ontologies and mappings shows that both approaches produce ontology mappings of high quality. Similarly, ontology changes may also affect ontology-based annotation mappings. The thesis introduces a generic evaluation approach to assess the quality of annotation mappings based on their evolution. Different quality measures allow for the identification of reliable annotations, e.g., based on their stability or provenance information. A comprehensive analysis of large annotation data sources shows numerous instabilities, e.g., due to the temporary absence of annotations. Such modifications may influence results of dependent applications such as functional enrichment analyses that describe experimental data in terms of ontological groupings. The question arises to what degree ontology and annotation changes may affect such analyses. Based on different stability measures the evaluation assesses change intensities of application results and gives insights whether users need to expect significant changes of their analysis results. Moreover, GOMMA is extended by large-scale ontology matching techniques. Such techniques are useful, a.o., to match new concepts during ontology mapping adaptation. Many existing match systems do not scale for aligning very large ontologies, e.g., from the life science domain. One efficient composition-based approach indirectly computes ontology mappings by reusing and combining existing mappings to intermediate ontologies. Intermediate ontologies can contain useful background knowledge such that the mapping quality can be improved compared to a direct match approach. Moreover, the thesis introduces general strategies for matching ontologies in parallel using several computing nodes. A size-based partitioning of the input ontologies enables good load balancing and scalability since smaller match tasks can be processed in parallel. The evaluation of the Ontology Alignment Evaluation Initiative (OAEI) compares GOMMA and other systems in terms of matching ontologies from different domains. Using the parallel and composition-based matching, GOMMA can achieve very good results w.r.t. efficiency and effectiveness, especially for ontologies from the life science domain.
Частини книг з теми "Gene ontology enrichment"
Gupta, Manoj Kumar, Gayatri Gouda, S. Sabarinathan, Ravindra Donde, Goutam Kumar Dash, Ramakrishna Vadde, and Lambodar Behera. "Gene Ontology and Pathway Enrichment Analysis." In Bioinformatics in Rice Research, 257–79. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-3993-7_12.
Повний текст джерелаPesquita, Catia, Tiago Grego, and Francisco Couto. "Identifying Gene Ontology Areas for Automated Enrichment." In Distributed Computing, Artificial Intelligence, Bioinformatics, Soft Computing, and Ambient Assisted Living, 934–41. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-02481-8_143.
Повний текст джерелаZhou, Tao, Jun Yao, and Zhanjiang Liu. "Gene Ontology, Enrichment Analysis, and Pathway Analysis." In Bioinformatics in Aquaculture, 150–68. Chichester, UK: John Wiley & Sons, Ltd, 2017. http://dx.doi.org/10.1002/9781118782392.ch10.
Повний текст джерелаP. Etukuri, Shalini, Varsha C. Anche, Mirzakamol S. Ayubov, Lloyd T. Walker, and Venkateswara R. Sripathi. "Transcriptome Analysis Using RNA Sequencing for Finding Genes Related to Fiber in Cotton: A Review." In Cotton [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.104572.
Повний текст джерелаSteenson, Sophie, Christopher Hawthorne, and Guillermo Lopez-Campos. "A Comparative Analysis of Phenotypes Derived from Genes or Biomedical Literature in COVID-19." In MEDINFO 2021: One World, One Health – Global Partnership for Digital Innovation. IOS Press, 2022. http://dx.doi.org/10.3233/shti220283.
Повний текст джерелаТези доповідей конференцій з теми "Gene ontology enrichment"
Peng, Jiajie, Guilin Lu, Hansheng Xue, Tao Wang, and Xuequn Shang. "TSGOE: A web tool for tissue-specific gene ontology enrichment." In 2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2018. http://dx.doi.org/10.1109/bibm.2018.8621204.
Повний текст джерела"Gene ontology enrichment and network analysis for differently expressed genes related to aggressive behavior." In SYSTEMS BIOLOGY AND BIOINFORMATICS. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 2019. http://dx.doi.org/10.18699/sbb-2019-40.
Повний текст джерелаIorio, Francesco, Loredana Murino, Diego di Bernardo, Giancarlo Raiconi, and Roberto Tagliaferri. "Gene ontology fuzzy-enrichment analysis to investigate drug mode-of-action." In 2010 International Joint Conference on Neural Networks (IJCNN). IEEE, 2010. http://dx.doi.org/10.1109/ijcnn.2010.5596585.
Повний текст джерелаCollar, Giovanna Carello, Marco Antônio De Bastiani, and Eduardo R. Zimmer. "HUNTINGTON’S DISEASE AND EARLYONSET ALZHEIMER’S DISEASE SHARE A TRANSCRIPTOMIC SIGNATURE." In XIII Meeting of Researchers on Alzheimer's Disease and Related Disorders. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1980-5764.rpda082.
Повний текст джерела