Дисертації з теми "Gefsoc"
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Coslovich, Davide. "Stima del sequestro potenziale di carbonio nei suoli agricoli del Veneto con il GEFSOC modellyng system." Doctoral thesis, Università degli studi di Trieste, 2011. http://hdl.handle.net/10077/4597.
Повний текст джерелаI suoli globalmente contengono circa 2500 Pg di C in forma minerale ed organica (ca 1550 Pg) ed il flusso annuo da e verso l’atmosfera – che attualmente contiene circa 760 Pg C – coinvolge circa 120 Pg di C. Questi scambi di carbonio sono clima-dipendenti; l’effetto del cambiamento climatico sui depositi di carbonio del suolo è perciò di importanza critica, in quanto anche piccole variazioni di un deposito di tale entità possono determinare importanti conseguenze sulla concentrazione di anidride carbonica in atmosfera, innescando meccanismi retroattivi positivi. Per fare delle previsioni sui cambiamenti dei depositi di carbonio per effetto dei cambiamenti climatici o di altre variabili è neccesario ricorrere a dei modelli; in particolare, per le stime a scala nazionale e regionale si impiegano dei modelli che operano a livello di ecosistema e che vengono abbinati a dei SIT. Vista la forte sinergia con la mitigazione e adattamento ai cambiamenti climatici, la ricerca è stata volta a stimare il potenziale di sequestro e accumulo di sostanza organica nei terreni agricoli del Veneto, con un occhio di riguardo per la gestione sostenibile. In secondo luogo, a fornire uno strumento per la contabilizzazione del sequestro di carbonio nei sistemi agricoli. Si è individuato nel GEFSOC Modelling Sistem uno strumento idoneo per il perseguimento di questi obiettivi; il GEFSOC MS integra due modelli meccanicistici ampiamente sperimentati – Century e RothC – ed il metodo empirico dell’IPCC e li interfaccia con un SOTER-DB e con un GIS. L’uso e la gestione del suolo ed i loro cambiamenti sono variabili fondamentali nel determinare il contenuto di carbonio nei depositi del terreno; poiché manifestano i loro effetti anche secoli dopo che si sono verificati, è necessario ricostruire la loro storia almeno negli ultimi 100 anni. Nel corso della ricerca è stato ideato e sperimentato per la prima volta in questo settore un approccio spazialmente esplicito alle transizioni di uso e gestione del suolo, utilizzando materiale cartografico di varia natura e completando la raccolta dati con statistiche agrarie e fonti storiche. Le simulazioni sono state fatte contemplando due diversi scenari di cambiamento climatico (PCM-B1 e Had3A1FI) spinti fino al 2100. L’analisi dei risultati prodotti evidenzia che i terreni più ricchi in carbonio sono maggiormente soggetti a perdite, mentre quelli poveri, anche se in misura modesta, incrementano il loro contenuto; la tendenza, quindi, è di avvicinarsi ad una maggiore omogeneità. Per quel che riguarda gli usi del suolo, seminativi ed aree agricole eterogenee sono le categorie che hanno manifestato tassi di incremento superiori. I tassi di variazione, comunque, sono tendenzialmente in calo e, per lo scenario di cambiamento climatico meno marcato, ad un certo punto (2070 ca) si portano su valori negativi: questo fatto si ripercuote sui depositi del terreno, che complessivamente mostrano un incremento nel lungo periodo, ma via via più contenuto, fino a raggiungere un massimo e quindi cominciare ad emettere negli ultimi decenni della simulazione. I depositi dei terreni sottoposti allo scenario di cambiamento più marcato, invece, non hanno subito flessioni ed hanno garantito, anche se in misura calante, il sequestro lungo tutto il periodo della simulazione. Questo dato può essere di qualche interesse nello studio degli effetti della temperatura sul rapporto produzione di biomassa-accumulo/decomposizione. L’analisi delle mappe dei depositi e dei tassi di variazione annua ad ettaro prodotte con la sperimentazione, ed il confronto delle stesse con carte del contenuto del carbonio nei terreni di doversa origine e natura, rivelano l’utilità dell’approccio spazialmente esplicito nella definizione delle transizioni dell’uso e gestione del suolo; è possibile infatti riconoscere, dalla zonizzazione, i tematismi che possono avere avuto un peso preponderante nel determinare peculiari situazioni; questo consente di indagarle, verificare la validità delle assunzioni fatte in fase di progettazione, modificare eventualmente la parametrizzazione e reindirizzare le simulazioni. Ad una livello di risoluzione comparabile a quello degli strati informativi di partenza. Alla luce della sperimentazione effettuata, si ritiene che il GEFSOC Modelling System meriti grande considerazione per quanto attiene la contabilizzazione del carbonio nei sistemi agricoli – problematica inevasa fino ad oggi in Italia; quale strumento a supporto del processo decisionale; per le possibili sinergie nella pianificazione di campionamenti e sperimentazioni attinenti; per l’approfondimento della ricerca nell’ambito delle relazioni tra clima e suolo.
XXIII Ciclo
1970
Severová, Petra. "Logistika firmy Gefco." Master's thesis, Vysoká škola ekonomická v Praze, 2008. http://www.nusl.cz/ntk/nusl-12250.
Повний текст джерелаZáruba, David. "Hodnocení finanční výkonnosti podniku GEFOS, a.s." Master's thesis, Vysoká škola ekonomická v Praze, 2017. http://www.nusl.cz/ntk/nusl-359397.
Повний текст джерелаSchuler, Gefion [Verfasser]. "»Politikbewertung« als Handlungsform internationaler Institutionen. : Das Beispiel der Korruptionsbekämpfung der OECD. / Gefion Schuler." Berlin : Duncker & Humblot, 2012. http://d-nb.info/1238427316/34.
Повний текст джерелаDumbrovská, Hana. "Analýza procesů s prázdnými obaly ve firmě GEFCO Česká republika." Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-197854.
Повний текст джерелаKinzel, Stephan. "Macht Cannabis psychisch krank? psychische Risiken von Cannabiskonsum /." [Schweiz] : [s.n.], 2006. http://www.baselland.ch/docs/vsd/gefoe/cannabiskonsum.pdf.
Повний текст джерелаŠtěrba, Martin. "Analýza přínosů zavedeného systému managementu kvality ve společnosti GEFCO ČESKÁ REPUBLIKA s.r.o." Master's thesis, Vysoká škola ekonomická v Praze, 2009. http://www.nusl.cz/ntk/nusl-76768.
Повний текст джерелаGirbig, Gefion Marlen [Verfasser], and Rebecca [Akademischer Betreuer] Schennach. "Die Matrixmetalloproteinase im Liquor als mögliches gemeinsames patho-physiologisches Korrelat der Depression und Schizophrenie / Gefion Marlen Girbig ; Betreuer: Rebecca Schennach." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2018. http://d-nb.info/1164376977/34.
Повний текст джерелаZhang, Ruosi. "Simulations of Different P-values Combination Methods Using SNPs on Diverse Biology Levels." Digital WPI, 2019. https://digitalcommons.wpi.edu/etd-theses/1317.
Повний текст джерелаNabbout, Rima. "Etude phénotypique et génotypique des convulsions fébriles et des épilepsies apparentées." Paris 6, 2003. http://www.theses.fr/2003PA066108.
Повний текст джерелаPersson, Örtman Lisa. "The suppressed goddess of Beowulf : A feminist reading of Grendel’s mother as a representation of Norse goddess Gefion in a changing world order." Thesis, Linnéuniversitetet, Institutionen för språk (SPR), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-82020.
Повний текст джерелаTazmini, Ghazaleh. "Regulatory mechanisms of the exchange factor RasGRP1." Thesis, University of British Columbia, 2008. http://hdl.handle.net/2429/2861.
Повний текст джерелаVoss, Ute. "Die Rolle von BIG ARF-GEFs in der Regulation des Vesikeltransports von Arabidopsis thaliana /." Tübingen, 2008. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000254318.
Повний текст джерелаLaštovičková, Eva. "Inbound logistics v automobilovém průmyslu a aktuální otázky týkající se služeb firmy GEFCO jako logistického integrátora pro klienta PSA Peugeot Citroën." Master's thesis, Vysoká škola ekonomická v Praze, 2007. http://www.nusl.cz/ntk/nusl-2300.
Повний текст джерелаRamsden, S. F. L. "The role of gephyrin, collybistin and novel GEFs in the synaptic clustering of inhibitory receptors." Thesis, University College London (University of London), 2012. http://discovery.ucl.ac.uk/1378553/.
Повний текст джерелаPan, Dingxin. "P-Rex1 : regulation by Norbin and cooperation with Vav family Rac-GEFs in inflammatory neutrophil recruitment." Thesis, University of Cambridge, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708001.
Повний текст джерелаmamta, jaiswal [Verfasser]. "Structural and Biochemical investigation of the activity, specificity and regulation of regulators (GEFs & GAPs) of the Rho family / jaiswal mamta." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2013. http://d-nb.info/1031075119/34.
Повний текст джерелаDupré, Émilie. "La protéine G hétérotrimérique G[indice inférieur q] interagit avec diverses GEFs d'ARF6 et l'activité GEF est impliquée dans l'endocytose du GPCR TP[bêta]." Mémoire, Université de Sherbrooke, 2006. http://savoirs.usherbrooke.ca/handle/11143/3844.
Повний текст джерелаDupré, Émilie. "La protéine G hétérotrimérique G[indice inférieur q] interagit avec diverses GEFs d'ARF6 et l'activité GEF est impliquée dans l'endocytose du GPCR TP[bêta]." [S.l. : s.n.], 2006.
Знайти повний текст джерелаHamann, Maren [Verfasser]. "The role of guanine nucleotide exchange factors (GEFs) in EGF-receptor signalling : Screening for a small molecule inhibitor of the Rin1-mediated Rab5 activation / Maren Hamann." Bonn : Universitäts- und Landesbibliothek Bonn, 2018. http://d-nb.info/1161462295/34.
Повний текст джерелаSousa, Gonçalo Nuno Neves Gonçalves Maldonado. "Routing optimization: GEFCO Portugal." Master's thesis, 2018. http://hdl.handle.net/10071/17901.
Повний текст джерелаO Transporte é considerado uma parte crucial de qualquer Cadeia de Abastecimento, visto ser responsável por interligar todos os agentes que fazem parte da mesma. Para obter máximo proveito na distribuição, é necessário otimizar as 3 variáveis que são referidas como os vértices do Triângulo Logístico: Custo, Tempo e Qualidade, o que significa que os produtos têm de chegar ao consumidor final no tempo certo, com o mínimo custo para a empresa e com a máxima qualidade possível. A otimização de rotas é uma das áreas de maior complexidade por haver diversas variáveis que não são mensuráveis nem podem ser controladas, dependendo sempre de cada cenário. Este projeto foi desenvolvido para estudar como a empresa consegue atingir a máxima qualidade de serviço enquanto existem fatores externos e internos que influenciam diretamente a distribuição dos pedidos dos clientes, além de restrições associadas a cada cenário. Assim sendo, o principal objetivo é otimizar várias rotas de distribuição que fornecem diariamente os diversos clientes da empresa. Este estudo está inserido nos Problemas de Rotas (VRP) e começou, primeiramente, por analisar o negócio da empresa e recolher os diversos tipos de dados que posteriormente foram tratados e analisados através do Microsoft Excel e das suas funcionalidades como, por exemplo, fórmulas e tabelas dinâmicas. Por fim, foram analisadas e apresentadas soluções e cenários através de um programa específico do Microsoft Excel (VRP Spreadsheet).
Schwarzerová, Lenka. "Systém vzdělávání společnosti GEFCO Česká republika." Master's thesis, 2008. http://www.nusl.cz/ntk/nusl-291176.
Повний текст джерелаFranke, Gefion [Verfasser]. "Etablierung eines GFP-basierten Reportergensystems in Staphylokokken / vorgelegt von Gefion Franke." 2006. http://d-nb.info/980585996/34.
Повний текст джерелаSantos, Ana Luísa da Palma. "Produção e Programação nas XVII Jornadas de Cultura Popular do GEFAC." Master's thesis, 2020. http://hdl.handle.net/10316/93763.
Повний текст джерелаProdução e Programação nas XVII Jornadas de Cultura Popular do GEFACEste relatório é o resultado descritivo e reflexivo do meu estágio curricular de Mestrado, realizado no âmbito do 2º ciclo de Estudos Artísticos, curso pertencente ao Departamento de História, Estudos Europeus, Arqueologia e Artes, da Faculdade de Letras da Universidade de Coimbra.A entidade de acolhimento escolhida foi o GEFAC – Grupo de Etnografia e Folclore da Academia de Coimbra, assumindo eu funções na organização e programação das XVII Jornadas de Cultura Popular, evento bienal, este ano com a temática “Ofícios, Cantos e Contos: A Mulher e a Cultura Popular”. O estágio aconteceu entre 1 de dezembro de 2018 e 31 de março de 2019.Neste documento abordo a história do GEFAC, o seu trabalho etnográfico, formativo e criativo, tentando enquadrá-los historicamente e apresentando também o Estado da Arte: investigações e abordagens relativas à cultura e música tradicional portuguesa. Abordo de seguida as Jornadas de Cultura Popular, uma atividade central do GEFAC, onde procuro fazer a sua contextualização histórica e social. Finalmente para a edição deste ano, cuja organização estive envolvida, procurarei expor criticamente os processos de criação do novo espetáculo geral, a produção e programação dos restantes concertos e palestras, a divulgação e finalmente as Jornadas em si, que aconteceram de 8 de março a 5 de abril em diversos espaços culturais da cidade de Coimbra. Concluo com uma resenha descritiva do meu estágio, com todas as atividades realizadas e também um balanço final.
Prodution and Programming in Gefac’s XVII Jornadas de Cultura Popular (Folk Culture’s Journeys)This report is the descriptive and reflexive output of my Masters curricular internship, carried out under the 2nd cycle of Arts Studies, course integrated in the History, European Studies, Archeology and Arts Department of Faculty of Arts and Humanities, University of Coimbra.The chosen host entity was GEFAC - Grupo de Etnografia e Folclore da Academia de Coimbra (Ethnography and Folklore Group of Coimbra’s Academy), assuming myself roles in the organization and programming of the XVII Jornadas de Cultura Popular, biennial event, this year under the theme “Ofícios, Cantos e Contos: A Mulher e a Cultura Popular” (Crafts, Songs and Tales: Woman and the Folk Culture). The internship took place between 2018 December 1st and 2019 March 31.In this document I approach GEFAC’s history, their ethnographic, formative and creative work, framing it historically and also offering a state of art about research and approaches to the Portuguese folk culture and music. Next I approach the Jornadas de Cultura Popular, a GEFAC central activity, wich I aim to contextualize historically and socially. Finally, for this year’s edition, in which organization I was involved, I will try to expose critically the creation processes of a new general show, the production and programming of the remaining concerts and talks, the promotion and finally the Jornadas itself, that happened between March 8th and April 5th, in different cultural venues in the city of Coimbra. I conclude with a descriptive review of my internship, with all the performed activities and also a final balance.
Brunnemann-Stubbe, Gefion [Verfasser]. "Physikalisch-chemische Eigenschaften troposphärischer Aerosolpartikel : Variabilität und meteorologische Anwendungen / von Gefion Brunnemann-Stubbe." 2002. http://d-nb.info/966271181/34.
Повний текст джерелаEsteves, João Pedro Nepomuceno. "Integração do transporte ferroviário no sector de distribuição automóvel: caso GEFCO Portugal." Master's thesis, 2019. http://hdl.handle.net/10400.26/30523.
Повний текст джерелаThe results obtained by the automotive industry are becoming increasingly significant, indicating the increase of production in Portugal and the adaptation of logistics sector to its own needs. This behavior shows that there is a concern to work with suppliers that can adapt to the requirements of the automotive sector. Since the rail freight mode has become more compatible with a sustainable transport system, it was made an analysis of its use when combined with other modes of transport. Intermodal transport is increasingly used in distribution streams, which allows each mode of transport to be allocated to a flow part according to its characteristics. This enables suppliers and customers to avail the advantages that each mode of transport has. According to the latest news about the use of railroad transport in the distribution of vehicles, this information reveals that this mode has been used as an alternative to road transport in Portugal. Following the dockers strike in the port of Setúbal, producers using this location as a shipping method felt the need to resort to alternatives for the distribution of their vehicles. Take the example of Autoeuropa that appealed to the port of Santander in Spain for its exports, where the rail transport was used to carry the finished vehicles from the factory to the port. This alternative served to identify the feasibility of reactivating rail transport between the Palmela plant and the port of Setúbal, where its conclusions allowed in September 2019 to announce the replacement of road transport by rail between this distribution flow. The railway infrastructure itself shows that new changes have been made, thus creating future opportunities for its use. The data from the distribution sector in Portugal show that transport volumes have been increasing steadily on an annual basis. This indicator enables the development of logistics activities in the automotive sector, where it is necessary to ensure regular operation in conjunction with the needs and requirements of suppliers and customers. Combining intermodal transport utilization trends with growth opportunities in the automobile distribution sector, it is essential to analyze their conjugation.
Laurin, Mélanie. "Étude sur les fonctions in vivo des GEFs DOCK chez les mammifères." Thèse, 2013. http://hdl.handle.net/1866/10877.
Повний текст джерелаDock1 (also known as Dock180) is the prototypical member of the Dock family of Rho GTPase activators (RhoGEFs). Genetic studies in Drosophila and C. elegans have demonstrated that Dock1 orthologues act upstream of the Rac GTPase to activate it during various biological processes. Myoblast city (mbc), Dock1 ortholog in the Drosophila, is an important regulator of myoblast fusion during muscle fiber formation. Moreover, mbc regulates the collective migration of a cluster of border cells downstream of the activation of some tyrosine kinase receptors (RTKs). Migration of border cells is often view as a model for studying the invasive migration of cancer cells during metastasis development. Work done in cell lines also suggests that Dock1 is an important cytoskeletal regulator that controls cell migration. The Dock1/Rac pathway was also shown to act downstream of some RTKs to promote the invasion of glioblastoma cells. Yet, the in vivo functions of Dock1 in mammals are still poorly understood and the identification and characterization of some of these functions is the main objective of my thesis. Guided by the function of mbc, in Aim #1 we revealed that Dock1 is essential to embryonic development by characterizing a Dock1 knock-out mouse model. A deficiency in myoblast fusion was observed in Dock1-null embryos which led to a reduction in their muscle mass. Furthermore, we uncovered a contribution of the other Dock1-related GEF, Dock5, to myofiber development. In Aim #2 a correlation between high level of DOCK1 expression and a poor prognosis in HER2+ breast cancer patients was revealed. Amplification or overexpression of the HER2 receptor tyrosine kinase is associated with near 20% of breast cancer cases. The presence of this genetic abnormality correlates with a poor prognosis and the development of metastasis. Biochemical and in vitro studies led us to identify that DOCK1 interacts with HER2 and is essential to HER2-mediated RAC activation and migration. The use of a HER2 breast cancer mouse model with Dock1 inactivation in the mammary gland led us to identify DOCK1-RAC signaling as novel effectors in HER2-mediated tumor growth and metastasis. We conclude that the use of Dock1 mouse models allowed us to identify some of the key functions regulated by this gene in vivo. Much like its ortholog mbc, Dock1 is essential to embryonic development and regulates myoblast fusion. Our study also reveals important degree of conservation of the mechanisms that regulate fusion between species. In addition, DOCK1 acts downstream of the HER2 RTK in mammary epithelial cells where it contributes to the progression of breast cancer pathology and the formation of metastasis induced by this oncogene.
Macakova, Lucie. "Srovnání směrů společenské odpovědnosti na příkladu 3 firem ze soukromého sektoru, společnosti GEFCO ČESKÁ REPUBLIKA s.r.o., Dalkia a.s., ABB,a.s." Master's thesis, 2012. http://www.nusl.cz/ntk/nusl-304761.
Повний текст джерелаTOFFALI, Lara. "Identification of Jak PTK-regulated rho-specific GEFs involved in activation of lymphocyte adhesion." Doctoral thesis, 2013. http://hdl.handle.net/11562/546549.
Повний текст джерелаThe rapid integrin affinity up-regulation is a crucial dynamic process in leukocyte recruitment that is controlled by a complex inside-out signalling pathway induced by chemokines. Small GTP binding proteins of rap and rho family are certainly the most studied signaling molecules involve in this pathway; in addition our recent data identified Jak PTKs as new upstream regulator of these small GTPases. Considering that Guanosine Exchange Factors (GEFs) are the main direct activators of small GTPases, they represent obvious molecule candidates to fill out the functional gap between Jak PTKs and rho-module. In this study we show the concurrent regulatory role of four rho specific GEFs Vav1, Sos1, Arhgef1 and Dock2 in CXCL12-induced LFA-1 affinity triggering and mediated-adhesion in human T lymphocytes. A reduced expression of these four molecules resulted in an impaired chemokine-induced LFA-1 affinity up-regulation and in a reduced cell adhesion to ICAM-1 in static and under-flow conditions. Importantly, CXCL12-activation of these four proteins is mediated by Jak PTKs and occurs in a time frame coherent with LFA-1 affinity triggering by chemokine. Moreover the activation of RhoA and Rac1 is strictly dependent on Vav1, Sos1, Arhgef1 and Dock2 activity. Collectively in this study we identified and fully characterized the role of four rho-GEFs in CXCL12-induced LFA-1 mediated adhesion providing a comprehensive signalling link between Jak PTKs and rho-module. Considering our results from a quantitative point of view, we observed some variability in the relative regulatory role of these proteins, with a major role for Vav1 and Sos1 with respect to Arhgef1 and Dock2 activity. This variable involvement of multiple rho-GEFs with apparently the same function may support the new emergent quantitative-concurrency view of signal transduction in which this complexity in mechanisms controlling integrin activation is essential to generate a very flexible signalling system able to efficiently respond to a variety of environmental conditions.
Buchwald, Ulf. "Investigation of yeast and Drosophila ARF proteins and their associated GEFs expressed in Saccharomyces cerevisiae." Doctoral thesis, 2011. https://repositorium.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-201101177664.
Повний текст джерелаMohanty, Smita. "Functionally Interacting Proteins : Analyses And Prediction." Thesis, 2012. http://etd.iisc.ernet.in/handle/2005/2534.
Повний текст джерела