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1
Fatia, Salma, Muhammad Ainul Yaqin, and Adi Heru Utomo. "Common Process Extraction pada Model Proses Bisnis Tebang Muat Angkut (TMA)." Jurnal Teknologi Informasi dan Terapan 7, no. 2 (December 18, 2020): 71–76. http://dx.doi.org/10.25047/jtit.v7i2.162.
Повний текст джерелаАнотація:
Abstract— In an organizational environment, there are various business process models with the same procedures. If an organization builds a system with the same procedure repeatedly, it will undoubtedly incur a lot of effort and money. Therefore, it is necessary to extract common fragments to save effort. This research uses four scenarios of business process models: sequence, branching, nested branching, and looping. This study uses Business Process Modeling Notation (BPMN) notation so that the process model consists of activities, connectors, and gateways. Structural similarity is measured using the Jaccard similarity formula by comparing the process model. The similarity of behavior is measured using the Transition Adjacency Relations (TARs) method to obtain common fragments. The results show that the sequence process model will produce a common fragment that tends to be sequential too. The branching will produce a common fragment that tends to branch, and nested branching will produce a common fragment that tends to be branched and nested, as well as looping will produce a common fragment contains looping too. The experimental results show that the proposed method can extract common fragments based on the available business process models.
 Keywords—BPMN; common fragment; behavioral similarity; TARs
 
 Abstrak— Dalam lingkungan organisasi, terdapat berbagai model proses bisnis dengan prosedur yang sama. Jika suatu organisasi membangun sistem dengan prosedur yang sama secara berulang-ulang, niscaya akan mengeluarkan banyak tenaga dan biaya. Oleh karena itu, perlu mengekstrak fragmen umum untuk menghemat tenaga. Penelitian ini menggunakan empat skenario model proses bisnis yaitu sequence, branching, nested branching, dan looping. Penelitian ini menggunakan notasi Business Process Modeling Notation (BPMN) sehingga model proses terdiri dari aktivitas, konektor, dan gateway. Kemiripan struktural diukur menggunakan rumus kemiripan Jaccard dengan membandingkan model proses. Kesamaan perilaku diukur menggunakan metode Transition Adjacency Relations (TARs) untuk mendapatkan fragmen yang sama. Hasil penelitian menunjukkan bahwa model sequence process akan menghasilkan common fragment yang cenderung berurutan juga. Percabangan akan menghasilkan fragmen umum yang cenderung bercabang, dan percabangan bersarang akan menghasilkan fragmen umum yang cenderung bercabang dan bersarang, serta perulangan akan menghasilkan fragmen umum yang berisi perulangan juga. Hasil eksperimen menunjukkan bahwa metode yang diusulkan dapat mengekstrak fragmen umum berdasarkan model proses bisnis yang tersedia.
 Keywords—BPMN; common fragment; kemiripan perilaku; TARs
2
Scappaticcio, Maria Chiara. "Dalla calligrafia alla letteratura: schegge di esametri latini in un’esercitazione scrittoria d’Egitto." Revue des Études Anciennes 123, no. 1 (2021): 221–33. http://dx.doi.org/10.3406/rea.2021.6985.
Повний текст джерелаАнотація:
La publication d’une nouvelle édition d’un fragment d’un exercice de calligraphie en latin, en provenance d’Egypte, et datant du premier siècle ap. J-C. (P. Mich. VII 459, in ZPE 2020), a permis d’identifier deux séquences textuelles. Ces deux fragments hexamétriques ne peuvent avec certitude être rattachés à un texte ou même à un auteur connu, mais semblent toutefois appartenir au genre épique. Le premier fragment consiste en une invocation à Jupiter (Iuppiter omnipotens). Le deuxième est un adjectif rarissime, auricomus/ lauricomus. Sans prétendre à une paternité certaine, ces deux possibles fragments d’hexamètres latins peuvent enrichir la collection des Fragmenta poetarum Latinorum anonymes.
3
Allen, David. "Fifth Fragment from Seven Fragments." Janus Head 4, no. 2 (2001): 356. http://dx.doi.org/10.5840/jh20014233.
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4
Riedweg, Christoph. "TrGF 2.624 – A Euripidean Fragment." Classical Quarterly 40, no. 1 (May 1990): 124–36. http://dx.doi.org/10.1017/s0009838800026835.
Повний текст джерелаАнотація:
In the authoritative new collection of the Tragicorum Graecorum Fragmenta (TrGF), a five-trimeter passage appears as No. 624 in the second volume which contains the ‘Fragmenta adespota’. Whereas Nauck placed the lines among the ‘Fragmenta dubia et spuria’ of Euripides (Eur. fr. 1131), Kannicht and Snell separate them totally from the Euripidean fragments and associate them with various pseudepigraphical pieces of tragic poetry which are commonly thought to have originated in the ‘workshop of a Jewish forger’. The purpose of my article is to challenge this decision and to show that TrGF 2.624 may well be genuine poetry by Euripides if we restore the lines to their probable original form. An attempt to reconstruct the original context of the fragment will also be added.
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Santiago, Graziele Da Silva, B. R. F. Campos, and Carla Rodrigues Ribas. "How does landscape anthropization affect the myrmecofauna of urban forest fragments?" Sociobiology 65, no. 3 (October 2, 2018): 441. http://dx.doi.org/10.13102/sociobiology.v65i3.3042.
Повний текст джерелаАнотація:
We evaluate whether landscape variables surrounding urban remnant forest fragments influence ant diversity and its components in urban areas. The study was conducted in six riparian forest fragments in midwestern Minas Gerais State, Brazil, by sampling epigaeic and arboreal ants. Arboreal ants respond to fragmente isolation with changes in alpha, beta and gamma diversities. Isolation likely hinders dispersion and re-colonization such that the more isolated a fragment is, the less likely that new species arrive there. On other hand, epigaeic diversity did not show any response to variables of the surroundings or fragments, probably because natural periodic floods constitute a more severe disturbance for these ants. In addition, throughout the process of urbanization, anthropogenic improvements, such as paving, that prevent the natural percolation of water, increase the flooding of riparian soil. Arboreal ant species composition responds to percentage of urban area, fragment area and distance from the urban center, while epigaeic ants respond only to fragment area and percentage of urban area. We believe that even with the loss of species diversity and anthropogenic influences on fragments within urban centers, these areas are still important for species conservation. We also suggest the development of environmental protection projects for riparian áreas within urban centers, including investments in ecological corridors connecting fragments and public policies seeking to preserve these areas.
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Klass, Keren, Sarie Van Belle, Alvaro Campos-Villanueva, Fernando Mercado Malabet, and Alejandro Estrada. "Effects of variation in forest fragment habitat on black howler monkey demography in the unprotected landscape around Palenque National Park, Mexico." PeerJ 8 (August 10, 2020): e9694. http://dx.doi.org/10.7717/peerj.9694.
Повний текст джерелаАнотація:
Habitat loss and fragmentation are leading threats to biodiversity today, and primates are particularly vulnerable to anthropogenic habitat disturbance. However, few studies have examined how differential effects of variation in forest fragment characteristics on males and females in a primate population may affect demography and population persistence. We quantified the effects of variation in forest fragment characteristics on the within-fragment demography of black howler monkeys (Alouatta pigra) in forest fragments around Palenque National Park, Mexico, and how these effects differed between adult males and females. We quantified forest loss in the landscape between 2000 and 2017, and used a redundancy analysis to examine the effects of 15 variables quantifying fragment dimensions, forest composition and physical structure, and isolation on fragment population size and density, the proportion of adult males and females in the fragment population, and the mean number of adult males and females per group in 34 fragments (N = 393 monkeys). We hypothesized that (i) population size is positively correlated with fragment area, while population density is negatively correlated, and (ii) the composition of fragment populations results from differential effects of fragment variables on adult males and females. Forest cover decreased by 23.3% from 2000 to 2017. Our results showed a significant effect of fragment variables on population demography in fragments, accounting for 0.69 of the variance in the demographic response variables. Population size increased with fragment area and connectivity, while density decreased. Larger, less isolated fragments with better connectivity, characteristics indicative of abundant secondary growth, and those with more diverse vegetation but lower Simpson’s evenness indices tended to have more adult females per group and a higher proportion of adult females in the population. In contrast, fragments that were largely similar in characteristics of forest composition and structure, but that were more isolated from nearby fragments, had more adult males per group and a higher proportion of adult males. These results may stem from black howler females preferentially remaining in natal groups and fragments when possible, and dispersing shorter distances when they disperse, while males may be more likely to disperse between fragments, traveling longer distances through the matrix to more isolated fragments. These differential effects on males and females have important conservation implications: if females are more abundant in larger, less isolated fragments, while males are more abundant in more isolated fragments, then to effectively conserve this population, both landscape connectivity and fragment areas should be maintained and increased.
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Hao, Ruijie, Jianya Yi, and Siman Guan. "Study on the temporal-spatial evolution process of axial preformed fragment power field." Journal of Physics: Conference Series 2891, no. 15 (December 1, 2024): 152015. https://doi.org/10.1088/1742-6596/2891/15/152015.
Повний текст джерелаАнотація:
Abstract The temporal-spatial evolution process of fragment power field is the basis for calculating the state of fragment-target encounter and damage assessment. In order to accurately describe the temporal-spatial evolution process of the fragment power field of the axial preformed fragment warhead, the numerical simulation method is used to analyse the fragment dispersion characteristics of different warheads, and the fragment velocity attenuation model is established by programming. The numerical simulation results are used as the initial value to substitute into the model to obtain the temporal-spatial evolution process and the hitting target process of the fragment power field. The results show that the multi-layer fragments will collide many times under the action of detonation load, and the collision will lead to the decrease of the average velocity of the same fragment layer and the increase of the scattering angle. After increasing the number of fragments, the outer fragments are more concentrated, but the average velocity is significantly reduced, and the fragment miss rate increases. This study can provide a calculation basis for the state of fragment-target encounter and the static and dynamic explosion test of fragment warhead.
8
Rajagopalan, S., and SV Pizzo. "Characterization of murine peritoneal macrophage receptors for fibrin(ogen) degradation products." Blood 67, no. 5 (May 1, 1986): 1224–28. http://dx.doi.org/10.1182/blood.v67.5.1224.1224.
Повний текст джерелаАнотація:
Abstract The binding of human fibrinogen degradation fragments D1, E, X, and Y, as well as fibrin fragment D1 dimer, to mouse peritoneal macrophages was examined. A Scatchard plot of fragment D1 binding was biphasic, suggesting two classes of receptors. Fragments D1, D1 dimer, X, and Y in low concentrations bound to macrophages with high affinity (Kd = 23 to 73 X 10(-11) mol/L). Fragment E bound specifically but at a much lower level than the other fragments. Fragment D1 was able to compete for the binding of radiolabeled fragments X and Y but not radiolabeled fragment E. These studies indicate that fragments D and E are recognized by separate receptor systems but that all of the fibrinogen degradation products that contain the D domain are recognized by the same receptor system.
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Rajagopalan, S., and SV Pizzo. "Characterization of murine peritoneal macrophage receptors for fibrin(ogen) degradation products." Blood 67, no. 5 (May 1, 1986): 1224–28. http://dx.doi.org/10.1182/blood.v67.5.1224.bloodjournal6751224.
Повний текст джерелаАнотація:
The binding of human fibrinogen degradation fragments D1, E, X, and Y, as well as fibrin fragment D1 dimer, to mouse peritoneal macrophages was examined. A Scatchard plot of fragment D1 binding was biphasic, suggesting two classes of receptors. Fragments D1, D1 dimer, X, and Y in low concentrations bound to macrophages with high affinity (Kd = 23 to 73 X 10(-11) mol/L). Fragment E bound specifically but at a much lower level than the other fragments. Fragment D1 was able to compete for the binding of radiolabeled fragments X and Y but not radiolabeled fragment E. These studies indicate that fragments D and E are recognized by separate receptor systems but that all of the fibrinogen degradation products that contain the D domain are recognized by the same receptor system.
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Held, Manfred. "Fragment Mass Distribution of “Secondary Fragments”." Propellants, Explosives, Pyrotechnics 16, no. 1 (February 1991): 21–26. http://dx.doi.org/10.1002/prep.19910160106.
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Triristanto, E. R., S. Husein, and M. Y. Y. Alfarobi. "Breccia for Diversion Tunnel Construction at Bener DAM in Purworejo, Central Java, Indonesia: Fragments, Matrix, RMR." IOP Conference Series: Earth and Environmental Science 1233, no. 1 (August 1, 2023): 012004. http://dx.doi.org/10.1088/1755-1315/1233/1/012004.
Повний текст джерелаАнотація:
Abstract This study aimed to explain the detailed engineering geology investigation which has breccia geological units on Diversion Tunnel at Bener Dam, Purworejo Regency, Central Java Province. The investigation includes geological conditions both breccia fragment and matrix, to Rock Mass Rating (RMR) values each unit. The data were taken from face mapping tunnel with interval 10 meters at inlet 1-390 and 841-865 meters. The findings showed that geological engineering units consisted of Monomict Breccia. The geological units can be divided into geological engineering; Monomict Breccia Matrix (RMR 72-92), Polymict Breccia Matrix (RMR 82), Andesite Fragmen (RMR 52-62), and Tuff Fragmen (RMR 79-84). The discovery of Andesite and Tuff Fragments needs to be handled differently than Monomict Breccia or Polymict Breccia. Andesite Fragment unit with discontinuity of sheeting joint requires rock bolt reinforcement to be installed perpendicular to the discontinuity plane. While the dominant unit is the Tuff Fragment which has a UCS value of 5-7 MPa, it is not recommended to use the blasting excavation method even though it has an RMR value of 79-84.
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Yoshioka, Haruhiko, Tsubasa Shimoda, Sota Oikawa, Satoko Morohashi, Yoshie Hasegawa, Kayo Horie, and Jun Watanabe. "Usefulness of Fractal Analysis of Kirsch Edge Images for the Tissue Fragment Inner Structure in Breast FNAB." Acta Cytologica 66, no. 2 (October 28, 2021): 149–58. http://dx.doi.org/10.1159/000519490.
Повний текст джерелаАнотація:
<b><i>Objective:</i></b> Recent advances in high-precision mammography and ultrasound screening have led to an increase in the detection of early lesions (ductal carcinoma in situ and small cancers) appearing as microcalcified lesions or microcystic images, and there needs to be an improvement in the accuracy of breast fine-needle aspiration biopsy (FNAB) assessing these lesions. The objective of this study was to investigate whether fractal analysis of Kirsch edge images for the tissue fragment inner structure (FKT) is useful in breast FNAB. FKT measures tissue fragment chromasia of hyperchromatic crowded tissue fragments (HCG), tissue fragment shape unevenness, and tissue fragment inner structure complexity. <b><i>Study Design Materials:</i></b> Nineteen epithelial tissue fragments of fibroadenoma (FA) from 7 patients and 52 tissue fragments of invasive breast carcinoma of no special type (IBC-NST) (grade 1–2) from 11 patients were assessed. First, tissue fragments were classified into small (smaller than 60 × 102 μm<sup>2</sup>), medium, and large (100 × 102 μm<sup>2</sup> or larger), and the appearance rate of each size was determined. Second, for FKT, the luminance value of tissue fragment chromasia, the unevenness and fractal value, and the tissue fragment inner structure complexity were determined. In statistical analysis, the Steel-Dwass test, nonlinear discriminant analysis, and receiver operating characteristic analysis were performed, setting the significance level at <i>p</i> &#x3c; 0.05. <b><i>Results:</i></b> “Unevenness of the tissue fragment shape,” “fractal value of the tissue fragment shape,” and “fractal value of the tissue fragment inner structure” were significantly higher in small and large tissue fragments in IBC-NST compared with those in FA. The specificity and sensitivity were the highest (100%) in small tissue fragments in multivariate analysis using 4 variables (“luminance value of tissue fragment chromasia,” “unevenness of tissue fragment shape,” “fractal value of the tissue fragment shape,” and “fractal value of the tissue fragment inner structure”). <b><i>Conclusion:</i></b> FKT, which evaluates “tissue fragment darkness,” “tissue fragment shape unevenness,” and “tissue fragment inner structure complexity” focusing on small tissue fragments of HCG in breast FNAB, is useful as a system that assists cytopathological assessment of breast FNAB.
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Luo, Naisong, Rui Sun, Yuwen Pan, Tianzhu Zhang, and Feng Wu. "Electron Microscopy Images as Set of Fragments for Mitochondrial Segmentation." Proceedings of the AAAI Conference on Artificial Intelligence 38, no. 4 (March 24, 2024): 3981–89. http://dx.doi.org/10.1609/aaai.v38i4.28191.
Повний текст джерелаАнотація:
Automatic mitochondrial segmentation enjoys great popularity with the development of deep learning. However, the coarse prediction raised by the presence of regular 3D grids in previous methods regardless of 3D CNN or the vision transformers suggest a possibly sub-optimal feature arrangement. To mitigate this limitation, we attempt to interpret the 3D EM image stacks as a set of interrelated 3D fragments for a better solution. However, it is non-trivial to model the 3D fragments without introducing excessive computational overhead. In this paper, we design a coherent fragment vision transformer (FragViT) combined with affinity learning to manipulate features on 3D fragments yet explore mutual relationships to model fragment-wise context, enjoying locality prior without sacrificing global reception. The proposed FragViT includes a fragment encoder and a hierarchical fragment aggregation module. The fragment encoder is equipped with affinity heads to transform the tokens into fragments with homogeneous semantics, and the multi-layer self-attention is used to explicitly learn inter-fragment relations with long-range dependencies. The hierarchical fragment aggregation module is responsible for hierarchically aggregating fragment-wise prediction back to the final voxel-wise prediction in a progressive manner. Extensive experimental results on the challenging MitoEM, Lucchi, and AC3/AC4 benchmarks demonstrate the effectiveness of the proposed method.
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Huschmann, Franziska U., Janina Linnik, Karine Sparta, Monika Ühlein, Xiaojie Wang, Alexander Metz, Johannes Schiebel, et al. "Structures of endothiapepsin–fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library." Acta Crystallographica Section F Structural Biology Communications 72, no. 5 (April 22, 2016): 346–55. http://dx.doi.org/10.1107/s2053230x16004623.
Повний текст джерелаАнотація:
Crystallographic screening of the binding of small organic compounds (termed fragments) to proteins is increasingly important for medicinal chemistry-oriented drug discovery. To enable such experiments in a widespread manner, an affordable 96-compound library has been assembled for fragment screening in both academia and industry. The library is selected from already existing protein–ligand structures and is characterized by a broad ligand diversity, including buffer ingredients, carbohydrates, nucleotides, amino acids, peptide-like fragments and various drug-like organic compounds. When applied to the model protease endothiapepsin in a crystallographic screening experiment, a hit rate of nearly 10% was obtained. In comparison to other fragment libraries and considering that no pre-screening was performed, this hit rate is remarkably high. This demonstrates the general suitability of the selected compounds for an initial fragment-screening campaign. The library composition, experimental considerations and time requirements for a complete crystallographic fragment-screening campaign are discussed as well as the nine fully refined obtained endothiapepsin–fragment structures. While most of the fragments bind close to the catalytic centre of endothiapepsin in poses that have been observed previously, two fragments address new sites on the protein surface. ITC measurements show that the fragments bind to endothiapepsin with millimolar affinity.
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WU, Z., I. NAGANO, E. POZIO, and Y. TAKAHASHI. "Polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP) for the identification of Trichinella isolates." Parasitology 118, no. 2 (February 1999): 211–18. http://dx.doi.org/10.1017/s0031182098003679.
Повний текст джерелаАнотація:
In the present study, polymerase chain reaction–restriction fragment length polymorphism (PCR–RFLP) analysis was developed to identify 5 species (Trichinella spiralis, Trichinella britovi, Trichinella nativa, Trichinella nelsoni and Trichinella pseudospiralis) and 3 phenotypes of uncertain taxonomic status (Trichinella T5, T6, and T8). Eleven restriction endonucleases were used to restrict 3 DNA fragments (1) a 2800 bp fragment of the 43 kDa excretory–secretory (E–S) protein gene, (2) a 1250 bp fragment amplified with the primer pair SB147A and (3) a 372 bp fragment amplified with the primer pair SB372A. This RFLP method allows the identification of the 8 Trichinella phenotypes as follows: T. spiralis by the HinfI or DdeI endonuclease restriction of the 2800 bp fragment; T. nativa by the RsaI restriction of the 2800 bp fragment, or by the AluI restriction of the 1250 bp fragment; T. britovi and Trichinella T8 by the AluI restriction of the 1250 bp fragments, and can be discriminated between them by the SspI restriction of the 2800 bp fragment; T. pseudospiralis by the MspI restriction of the 372 bp fragment; T. nelsoni by the HhaI or AluI restriction of the 2800 bp fragment; Trichinella T5 by the HhaI restriction of the 2800 bp fragment; Trichinella T6 by the AluI restriction of the 1250 bp fragment; and Trichinella T8 by the SspI or RsaI restriction of the 2800 bp fragment. This study reveals also an intraspecifies polymorphism in the 2800 bp and 1250 bp fragments for T. britovi, Trichinella T5 and T6.
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Zhang, Yong, Yue-Guang Yan, Chen-Xu Wang, and Chao Ge. "Numerical simulation study on detonation effect of fragment impact covered explosive." Journal of Physics: Conference Series 2891, no. 13 (December 1, 2024): 132006. https://doi.org/10.1088/1742-6596/2891/13/132006.
Повний текст джерелаАнотація:
Abstract In order to reveal the detonation effect and mechanism of covered explosive under fragment impact, based on one-dimensional shock wave theory, a theoretical model of fragment impact detonation of covered explosive is established. Combined with numerical simulation, the influence of key parameters such as fragment material, fragment shape and charge shell thickness on the detonation threshold velocity and the influence of fragment velocity on the detonation time and depth of covered explosive are obtained, and the mechanism of fragment on the detonation effect of covered explosive is revealed. The results show that the shock initiation effect of tungsten alloy fragments is better than that of 45# steel fragments. The shock initiation effect of cubic fragments is better than that of spherical fragments. When the thickness of charge shell is thin, it is the impact detonation mechanism. When the charge shell is thick, the impact detonation mechanism and the shear detonation mechanism coexist. The detonation time and detonation depth of explosives decrease with the increase of velocity, and the detonation time is proportional to the detonation depth.
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Maldonado-Coelho, Marcos, and Miguel Â. Marini. "Effects of Forest Fragment Size and Successional Stage on Mixed-Species Bird Flocks in Southeastern Brazil." Condor 102, no. 3 (August 1, 2000): 585–94. http://dx.doi.org/10.1093/condor/102.3.585.
Повний текст джерелаАнотація:
Abstract We analyzed patterns of species richness, size, structure, and composition of mixed-species flocks in relation to forest fragment size and forest successional stage during dry and rainy seasons, at the state of Minas Gerais, southeastern Brazil. Three forest fragments (1.7, 50, and 200 ha) were used for fragment size analysis, and two fragments (200 and 300 ha) were used for successional stage analysis. Fragment size and season affected flock richness, size, stability, and composition. In the 1.7-ha fragment, flock species richness, size, and stability were significantly different only during the rainy season. Fragment successional stage also influenced flock richness and size, although season did not. Flock composition also had changes related to fragment successional stage. Fragment geometry seems to be an important factor influencing flock structure and composition.
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Ge, M., T. J. Ryan, H. Lum, and A. B. Malik. "Fibrinogen degradation product fragment D increases endothelial monolayer permeability." American Journal of Physiology-Lung Cellular and Molecular Physiology 261, no. 4 (October 1, 1991): L283—L289. http://dx.doi.org/10.1152/ajplung.1991.261.4.l283.
Повний текст джерелаАнотація:
We assessed the effects of the two primary high-molecular-weight fibrinogen degradation products (FDP), fragments D and E, on the pulmonary vascular endothelial barrier function. Fragments D and E were purified to homogeneity by QAE Sephadex chromatography followed by gel filtration. Incubation of bovine pulmonary artery endothelial monolayers with 0.5–2.0 microM fragment D for 2 h caused a doubling of transendothelial 125I-albumin clearance rate (a measure of 125I-albumin permeability). Fragment E only produced a 0.6-fold increase in 125I-albumin clearance rate at concentration of 4.0 microM. Both FDP remained active in incubating media with serum. The permeability-increasing effect of fragment D was reversible and was not due to cell detachment or lysis. The fragment-D effect was time dependent and was associated with redistribution of endothelial F-actin microfilaments. The effect was independent of the carboxy-terminal sequence on gamma-chain of fragment D. Fragments D and E binding to pulmonary artery endothelial cells was specific and reversible, but fragment D binding was three-fold greater than fragment E, which may account for the greater permeability increase mediated by fragment D. The results indicate that FDP, especially fragment D, increase endothelial permeability to albumin. The response involves specific binding of fragment D to endothelial cells and redistribution of intracellular actin.
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Zhang, Xiaoqian, and Hanshan Li. "A Target Damage Assessment Mathematical Model and Calculation Method Based on the Intersection of Warhead Fragment and Target Mechanism." Mathematics 10, no. 17 (August 29, 2022): 3101. http://dx.doi.org/10.3390/math10173101.
Повний текст джерелаАнотація:
This paper proposes a target damage calculation method based on the profit-loss value of a warhead fragment group. The group is discretized into a fan-shaped column warhead fragment dispersion arrangement model, and the angle of its intersection with the target is combined to establish the dynamic dispersion density model of the warhead fragment group. In addition, the function to calculate the number of warhead fragments hitting the target’s surface is devised. The capability matrix of the warhead fragment group is constructed according to the quality, quantity, and storage velocity of the warhead fragments, and then, the profit-loss value of the warhead fragment group is established. Combining the intersection probability of the target and the warhead fragment of the dispersion area, the model to calculate the probability of damage caused to the target by the warhead fragment group formation is deduced. The calculation and experimental analysis verifies that the dispersion angle of warhead fragments, the intersection angle of projectile and target, and the intersection distance of projectile and target significantly influence the impact of target damage.
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Berenger, Francois, David Simoncini, Arnout Voet, Rojan Shrestha, and Kam Y. J. Zhang. "Fragger: a protein fragment picker for structural queries." F1000Research 6 (September 22, 2017): 1722. http://dx.doi.org/10.12688/f1000research.12486.1.
Повний текст джерелаАнотація:
Protein modeling and design activities often require querying the Protein Data Bank (PDB) with a structural fragment, possibly containing gaps. For some applications, it is preferable to work on a specific subset of the PDB or with unpublished structures. These requirements, along with specific user needs, motivated the creation of a new software to manage and query 3D protein fragments. Fragger is a protein fragment picker that allows protein fragment databases to be created and queried. All fragment lengths are supported and any set of PDB files can be used to create a database. Fragger can efficiently search a fragment database with a query fragment and a distance threshold. Matching fragments are ranked by distance to the query. The query fragment can have structural gaps and the allowed amino acid sequences matching a query can be constrained via a regular expression of one-letter amino acid codes. Fragger also incorporates a tool to compute the backbone RMSD of one versus many fragments in high throughput. Fragger should be useful for protein design, loop grafting and related structural bioinformatics tasks.
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Berenger, Francois, David Simoncini, Arnout Voet, Rojan Shrestha, and Kam Y. J. Zhang. "Fragger: a protein fragment picker for structural queries." F1000Research 6 (April 10, 2018): 1722. http://dx.doi.org/10.12688/f1000research.12486.2.
Повний текст джерелаАнотація:
Protein modeling and design activities often require querying the Protein Data Bank (PDB) with a structural fragment, possibly containing gaps. For some applications, it is preferable to work on a specific subset of the PDB or with unpublished structures. These requirements, along with specific user needs, motivated the creation of a new software to manage and query 3D protein fragments. Fragger is a protein fragment picker that allows protein fragment databases to be created and queried. All fragment lengths are supported and any set of PDB files can be used to create a database. Fragger can efficiently search a fragment database with a query fragment and a distance threshold. Matching fragments are ranked by distance to the query. The query fragment can have structural gaps and the allowed amino acid sequences matching a query can be constrained via a regular expression of one-letter amino acid codes. Fragger also incorporates a tool to compute the backbone RMSD of one versus many fragments in high throughput. Fragger should be useful for protein design, loop grafting and related structural bioinformatics tasks.
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Qifei, Meng, Men Jianbing, Nan Yuxiang, and Liu Shiyu. "Initial velocity circumferential distribution model of Multi-layer spherical premade fragments." Journal of Physics: Conference Series 2891, no. 9 (December 1, 2024): 092002. https://doi.org/10.1088/1742-6596/2891/9/092002.
Повний текст джерелаАнотація:
Abstract To calculate the force field of multi-layer spherical premade fragment warheads, a calculation model for the initial velocity of multi-layer spherical fragments is constructed. Based on the scattering process of multi-layered spherical fragments under explosive loading, the fragment driving process is divided into three stages: common motion, filler penetration, and fragment delamination. A multi-layer spherical fragment circumferential initial velocity calculation model was constructed by combining the Stanovich model and Gurney model, using the momentum theorem and energy conservation law. Conducting numerical simulations and pulse X-ray verification experiments on the explosive loading of fragment warheads under different levels of fragment layers, the numerical simulation and experimental results show that when the number of fragment layers is less than 4, the average velocity of each layer calculated by the model has an average error of less than 15% compared to the simulation and experiment, which can basically achieve prediction of the initial velocity and distribution of premade fragments scattered along the circumferential direction in each layer.
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Shang, Fei, and Liangquan Wang. "Typical Fragment Kinetic Energy Assessment Based on Acoustic Emission Technology." Sensors 22, no. 15 (August 8, 2022): 5914. http://dx.doi.org/10.3390/s22155914.
Повний текст джерелаАнотація:
Fragment kinetic energy is an important parameter to characterize the damage power of fragments. In this study, an acoustic emission technology-based method to evaluate fragment kinetic energy is proposed. The dynamic response of the fragment impacting an aluminum alloy target plate and the relationship between the initial kinetic energy of the fragment impact and the acoustic emission waveform were theoretically evaluated; the numerical simulation of typical spherical fragments (8 mm diameter) penetrating the aluminum alloy target plate was performed, the wavelet energy of the acoustic emission signal was obtained using wavelet packet theory, and a mathematical model of wavelet energy and fragment kinetic energy was constructed. A fragment kinetic energy test system was established, and a fragment penetration test was performed. The analysis showed that the wavelet energy mathematical models and the fragment kinetic energy exhibited favorable consistency, and the measurement errors of the three experiments were 3%, 3.7%, and 3%. This demonstrates the effectiveness of the typical acoustic emission fragment kinetic energy test methods proposed in this study and establishes a new method for the direct measurement of fragment kinetic energy.
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Wu, Di, Xiao-Yuan Jing, Haowen Chen, Xiaohui Kong, and Jifeng Xuan. "Recommending Relevant Tutorial Fragments for API-Related Natural Language Questions." International Journal of Software Engineering and Knowledge Engineering 31, no. 09 (September 2021): 1251–75. http://dx.doi.org/10.1142/s0218194021500406.
Повний текст джерелаАнотація:
Application Programming Interface (API) tutorial is an important API learning resource. To help developers learn APIs, an API tutorial is often split into a number of consecutive units that describe the same topic (i.e. tutorial fragment). We regard a tutorial fragment explaining an API as a relevant fragment of the API. Automatically recommending relevant tutorial fragments can help developers learn how to use an API. However, existing approaches often employ supervised or unsupervised manner to recommend relevant fragments, which suffers from much manual annotation effort or inaccurate recommended results. Furthermore, these approaches only support developers to input exact API names. In practice, developers often do not know which APIs to use so that they are more likely to use natural language to describe API-related questions. In this paper, we propose a novel approach, called Tutorial Fragment Recommendation (TuFraRec), to effectively recommend relevant tutorial fragments for API-related natural language questions, without much manual annotation effort. For an API tutorial, we split it into fragments and extract APIs from each fragment to build API-fragment pairs. Given a question, TuFraRec first generates several clarification APIs that are related to the question. We use clarification APIs and API-fragment pairs to construct candidate API-fragment pairs. Then, we design a semi-supervised metric learning (SML)-based model to find relevant API-fragment pairs from the candidate list, which can work well with a few labeled API-fragment pairs and a large number of unlabeled API-fragment pairs. In this way, the manual effort for labeling the relevance of API-fragment pairs can be reduced. Finally, we sort and recommend relevant API-fragment pairs based on the recommended strategy. We evaluate TuFraRec on 200 API-related natural language questions and two public tutorial datasets (Java and Android). The results demonstrate that on average TuFraRec improves NDCG@5 by 0.06 and 0.09, and improves Mean Reciprocal Rank (MRR) by 0.07 and 0.09 on two tutorial datasets as compared with the state-of-the-art approach.
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Kuhar, Kristijan, and Marko Medved. "Novootkriveni glagoljski fragmenti iz 14.-15. st. u arhivu riječkih benediktinki." Fluminensia 33, no. 2 (2021): 461–80. http://dx.doi.org/10.31820/f.33.2.7.
Повний текст джерелаАнотація:
Rad ukazuje na pronađene fragmente iz samostana benediktinki Sv. Roka u Rijeci čije se arhivsko gradivo danas nalazi u samostanu Sv. Danijela u Abano Terme u Italiji, gdje su riječke redovnice izbjegle nakon Drugog svjetskog rata. Od tri pronađena, članak opisuje jedan glagoljski fragment na uglatoj glagoljici kojemu pristupa kroz paleografsku, kodikološku, teološko i liturgijsko-povijesnu analizu. Donosi se transliteracija teksta i zaključuje se da je fragment pripadao brevijaru iz razdoblja kraja 14. ili 15. stoljeća te da je vezan uz liturgijsko svetkovanje sv. Martina biskupa i ispovjednika. Pronalazak fragmenta smješta se u dosadašnje spoznaje o liturgijsko-jezičnoj povijesti Rijeke i iznose se hipoteze o načinu na koji je dospio u samostan riječkih benediktinki, zajednicu koju se smatra latinaškom.
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Liu, Guifeng, Yuxin Xu, and Qingze Li. "Research on Velocity Test of Fragment Group of Gradient Scattering Preformed Fragment Warhead." Journal of Physics: Conference Series 2891, no. 8 (December 1, 2024): 082021. https://doi.org/10.1088/1742-6596/2891/8/082021.
Повний текст джерелаАнотація:
Abstract In order to obtain the velocity of the fragment group of gradient scattering preformed fragment warhead, the radial scattering field of the fragments was photographed by the laser high-speed CCD camera system, and the velocities of all the fragments in the image after filtering the explosion firelight were obtained. The velocity of the preformed fragments shows a continuous gradient distribution from 77.9 m/s to 424.2 m/s, which was consistent with the theoretical calculation results. This indicates that the test technology is feasible and provides a new method for the velocity test of the fragment group.
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Pradnya, Prashant Shinde Monika Gopal Shinde. "Fragment Based Drug Design: A Review." International Journal in Pharmaceutical Sciences 2, no. 7 (July 1, 2024): 171–76. https://doi.org/10.5281/zenodo.12610829.
Повний текст джерелаАнотація:
Effective small molecule development can be achieved through the use of fragment based drug design. Several powerful compounds with a wide range of targets have been created with this method. Finding tiny chemical fragments that bind to biological targets and can then be refined to resemble lead molecules is known as ‘fragment-based drug design’. The methods for identifying fragments, screening them, and turning them into hits or leads—including fragment growth, fragment linking, fragment self-assembly, and targeted libraries—are covered in this article. FBDD will be more crucial to drug development since it is easily conducted using a variety of biophysical and computer-based techniques.
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Zhu, X. J., S. S. Kang, K. Hargrove, D. Shochat, M. Jarrells, M. Mojesky та S. K. Chan. "The identification of epitopic sites in human α1-proteinase inhibitor". Biochemical Journal 246, № 1 (15 серпня 1987): 25–36. http://dx.doi.org/10.1042/bj2460025.
Повний текст джерелаАнотація:
Human α 1-proteinase inhibitor (α 1-PI) yielded nine fragments on cleavage with CNBr. The amino acid sequences of these fragments were determined. Three of these CNBr-cleavage fragments, namely fragment I (residues 64-220), fragment II (residues 243-351) and fragment III (residues 1-63), were found to bind rabbit polyclonal antibodies against chemically oxidized α 1-PI and mouse polyclonal antibodies against native α 1-PI by the Bio-Dot method (enzyme-linked immunosorbent assay on nitrocellulose). These fragments, I, II and III, inhibited by 60%, 25% and 5% respectively the binding between α 1-PI and the rabbit antibodies. Fragments I, II and III were subjected to proteolytic digestion, and 15, ten and five peptides were obtained from these fragments respectively. Only four of these peptides showed binding to the mouse antibodies against native α 1-PI. These were residues 40-63, 79-86, 176-206 and 299-323. A panel of monoclonal antibodies was prepared by conventional hybridoma technology, with chemically oxidized α 1-PI as the antigen. The ability of the monoclonal antibodies to bind native α 1-PI and CNBr-cleavage fragments I-III was determined. The monoclonal antibodies fell into three categories. Most (over 90%) belonged to group I, which was capable of binding α 1-PI and only fragment I. Antibodies in groups II and III bound α 1-PI and either fragment II or fragment III respectively. The ability of the peptides derived from proteolytic digestion of fragments I, II and III to bind three monoclonal antibodies representing each of the three groups was determined. Among all the peptides tested, only one (residues 176-206) derived from fragment I showed binding to the antibodies from group I, one (residues 299-323) derived from fragment II showed binding to the antibodies from group II, and one (residues 40-63) from fragment III showed binding to the antibodies from group III. Each of these three peptides also inhibited the binding between α 1-PI and the corresponding monoclonal antibodies. From these data we concluded that at least four epitopic regions (residues 40-63, 79-86, 176-206 and 299-323) were present in α 1-PI. Specific monoclonal antibodies to three of these sites were obtained.
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Ogata, K., Y. Ogata, Y. Takasaki, and E. M. Tan. "Epitopes on proliferating cell nuclear antigen recognized by human lupus autoantibody and murine monoclonal antibody." Journal of Immunology 139, no. 9 (November 1, 1987): 2942–46. http://dx.doi.org/10.4049/jimmunol.139.9.2942.
Повний текст джерелаАнотація:
Abstract The immune epitopes of proliferating cell nuclear antigen (PCNA), also called cyclin, were analyzed by determining the reactivity between PCNA peptide fragments and anti-PCNA antibodies from lupus patients, murine monoclonal antibody (19A2), and rabbit anti-NH2-terminal peptide antibody. Limited digestion of PCNA/cyclin with Staphylococcus aureus V8 protease resulted in several peptide fragments. Five fragments of 30, 20, 15, 14, and 13 kDa were reactive with rabbit anti-NH2-terminal peptide antibody denoting that they contained the NH2-terminal peptide. The 30- and 20-kDa fragments reacted with 19A2 but the others did not. Lupus sera reacted with 17- and 15-kDa peptide fragments allowing their classification into three groups. Two of eight sera (type A) reacted only with the 17-kDa fragment. Two others (type B) reacted with both the 17- and 15-kDa fragments and the remaining four sera (type C) reacted only with the 15-kDa fragment. The sera reacting with the 15-kDa fragment also reacted with the 20-kDa fragment, but the sera reactive only with the 17-kDa fragment did not, indicating that the 17-kDa fragment was not a degradation product of 20-kDa fragments. The 19A2 epitope resided in the region between 15 and 20 kDa from the NH2 terminus, whereas there was at least one distinct epitope on each 15- and 17-kDa peptide, which were recognized by lupus autoantibodies.
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Alimov, A. P., S. Y. Yusupov, Sh K. Khakimov, A. Sh Muminov, and Sh Sh Akhmedov. "MODERN OSTEOSYNTHESIS TECHNIQUES IN SHOULDER BONE PROXIMAL FRACTURES." UZBEK MEDICAL JOURNAL 2, no. 5 (May 30, 2021): 49–58. http://dx.doi.org/10.26739/2181-0664-2021-5-10.
Повний текст джерелаАнотація:
This article discusses the issues of choosing a treatment method for proximal humerus fractures and how the proposed minimally invasive method of osteosynthesis for fractures of the proximal humerus allows less traumatic repositioning of bone fragments andmore stable fixation of bone fragments. A less invasive osteosynthesis method for fractures of the proximal humerus allows less traumatic repositioning of bone fragments and more stable fixation of bone fragments. Improve treatment results by developing aminimally invasive method of extramedullary treatment for fractures of the proximal humerus.. This research work was carried out in clinical bases of RITOIAM and RSHTYoIM Bukhara branch in patients with multiple fragment fractures of the proximal part of the shoulder bone with 40, 15 of which were found to be moved in the varus state of the bone fragments. Patients were divided according to gender and 15 were male and 25 were female. The duration of the trip was an average of 5,8±1,8 days (3 –7 days). In order to assess the status of bone fragments in multi –fragment fractures in patients, the classification of Neer (1970) was used: single –fragment, 10 (25%) –two-fragment, 12 (30%) -three-fragment and the remaining 12 (30%) -multiple-fragment fractures in 6 (15 %) patients. In shoulder bone proximal fractures, osteosynthesis was performed with a less invasive blocking plate through an external distraction apparatus developed in the clinic and a small-sized wound incision.
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Wang, Zhenning, Junhui Yang, Jianping Yin, Xudong Li, Rui Shi, and Jianya Yi. "Study on Joint Damage of Double Prefabricated Fragments Penetrating Finite Thickness Concrete." Shock and Vibration 2023 (April 3, 2023): 1–17. http://dx.doi.org/10.1155/2023/1528983.
Повний текст джерелаАнотація:
In order to study the joint damage mechanism of multiple prefabricated fragments to finite thickness concrete targets, experiments on the damaging effect of a single fragment on a 300 × 300 × 100 mm concrete target were carried out, and the reliability of the simulation calculation model of single fragment damage to concrete was verified. On this basis, according to the trajectory of two fragments penetrating concrete, the double fragment penetration is divided into two penetration situations, that is, coplanar and heterogeneous. The orthogonal optimization method is used to carry out the joint damage simulation calculation of the double fragments to the concrete target by changing the fragment velocity, penetration angle, fragment spacing, and other factors. The simulation results show that the relationship between joint damage and fragment spacing is the largest when the fragment trajectories are coplanar, and the partial least squares regression coefficients affecting the joint damage time and surface joint length are 0.70 and 0.68 respectively. When the trajectory is different, the joint damage mode is relatively complex. Based on this, the joint damage degree analysis method between fragments is established, and each variable can explain 73.8% of the joint damage degree. It is found that the joint damage of the front pit area is the largest when the fragment is in different planes, and the PLS regression coefficient is −0.44. The hypothesis that joint damage is easy to occur in the area of the intersection line on the back of the target is analyzed and verified.
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VAIDOGAS, Egidijus. "Explosions of Cylindrical Pressure Vessels Subjected to Fire: Probabilistic Prediction of a Number of Fragments." Mechanics 27, no. 4 (August 27, 2021): 277–84. http://dx.doi.org/10.5755/j02.mech.29014.
Повний текст джерелаАнотація:
The aim of this study was to propose a procedure for a prediction of the number of fragments generated by fire induced explosions of cylindrical pressure vessels. The prediction is carried out in terms of probabilities of individual fragment numbers. The prevailing numbers of two to four fragments are considered. The fragment number probabilities are estimated by applying data on vessel fragmentations acquired in investigations of past explosion accidents. The pressure vessel explosions known as BLEVEs are considered. The Bayesian analysis is used for the estimation of the fragment number probabilities. This analysis is carried out on the basis of Poisson-gamma model. An approach to developing a gamma prior distribution for the average number of fragments per explosion accident is proposed. The assessment of the fragment number probabilities is carried out by propagating uncertainty related to the average number of fragments to uncertainty in the fragment number probabilities. The stochastic (Monte Carlo) simulation is used for this propagation. Findings of this study are viewed as a possibility to improve the assessment of risk posed by pressure vessel explosions.
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Carcedo de Andrés, Bruno Pedro. "Dos fragmentos de estelas romanas procedentes de Lara de los Infantes (Burgos) = Two Fragments of Roman Steles from Lara de los Infantes (Burgos)." Espacio Tiempo y Forma. Serie II, Historia Antigua, no. 33 (November 1, 2020): 183. http://dx.doi.org/10.5944/etfii.33.2020.27379.
Повний текст джерелаАнотація:
Este trabajo analiza dos fragmentos de inscripciones romanas procedentes de la zona de Lara de los Infantes (Burgos). El primero de ellos es un fragmento anepigráfico con representación de una figura humana femenina. El segundo corresponde a un fragmento de estela romana en el que se intuye una denominación mediante doble idiónimo. En definitiva, se trata de dos nuevos testimonios epigráficos a añadir al profuso corpus de una zona rica en hallazgos epigráficos pero pobre en intervenciones arqueológicas que los contextualicen.This work analyzes two fragments of roman inscriptions from the area of Lara de los Infantes (Burgos). The first one is an anepigraphic fragment with a representation of a female human figure. The second fragment come from a roman stele in which a denomination by double idionym could be deduced. Ultimately, these are two new epigraphic testimonies to be added to the extense corpus of a very rich area in epigraphic findings but poor in archaeological works which contextualize them.
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MacIntosh, T., B. J. M. Stutchbury, and M. L. Evans. "Gap-crossing by Wood Thrushes (Hylocichla mustelina)in a fragmented landscape." Canadian Journal of Zoology 89, no. 11 (November 2011): 1091–97. http://dx.doi.org/10.1139/z11-090.
Повний текст джерелаАнотація:
We used radio-telemetry to study the movement patterns of Wood Thrushes ( Hylocichla mustelina (J.F. Gmelin, 1789)) occupying small forest fragments (<5 ha) to examine gap-crossing between fragments and edge use within fragments. We found that 82% (8/11) of males and 33% (2/6) of females made at least one foray off of its resident forest fragment and we documented a total of 26 off-fragment forays (n = 79 h tracking). Males spent, on average, 23.5% of their time off their fragment, while females were gone 12.8% of the time tracked. Most forays were >150 m in distance and foray rate to adjacent fragments declined with increasing gap width. Males on fragments spent more time off their territory (23.5%) and traveled farther (392 m) than males occupying territories within a continuous forest (4.8% and 99 m, respectively). In fragments, 10 out of 17 individuals spent >80% of their time within 20 m of the fragment edge and edge use was significantly more than expected based on the amount of edge available in each fragment. This study adds to the growing evidence for migratory songbirds that during the breeding season, forest fragmentation may increase rather than impede daily movements.
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Rathee, Manisha, and T. V. Vijay Kumar. "DNA Fragment Assembly Using Multi-Objective Genetic Algorithms." International Journal of Applied Evolutionary Computation 5, no. 3 (July 2014): 84–108. http://dx.doi.org/10.4018/ijaec.2014070105.
Повний текст джерелаАнотація:
DNA Fragment Assembly Problem (FAP) is concerned with the reconstruction of the target DNA, using the several hundreds (or thousands) of sequenced fragments, by identifying the right order and orientation of each fragment in the layout. Several algorithms have been proposed for solving FAP. Most of these have solely dwelt on the single objective of maximizing the sum of the overlaps between adjacent fragments in order to optimize the fragment layout. This paper aims to formulate this FAP as a bi-objective optimization problem, with the two objectives being the maximization of the overlap between the adjacent fragments and the minimization of the overlap between the distant fragments. Moreover, since there is greater desirability for having lesser number of contigs, FAP becomes a tri-objective optimization problem where the minimization of the number of contigs becomes the additional objective. These problems were solved using the multi-objective genetic algorithm NSGA-II. The experimental results show that the NSGA-II-based Bi-Objective Fragment Assembly Algorithm (BOFAA) and the Tri-Objective Fragment Assembly Algorithm (TOFAA) are able to produce better quality layouts than those generated by the GA-based Single Objective Fragment Assembly Algorithm (SOFAA). Further, the layouts produced by TOFAA are also comparatively better than those produced using BOFAA.
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Sukma, Adjit Royan Mustafa Ganda, Haryo Untoro, Muhammad Siswoyo, and Nanda Nursa Alya. "Fragmen Labuhan Merapi: Pengimplementasian Folklor Ki Sapu Jagad dalam Seni Pertunjukan, Beserta Sejarah Perkembangan dan Pelestariannya (Sebuah Kajian Budaya)." Arnawa 1, no. 1 (June 5, 2023): 10–21. http://dx.doi.org/10.22146/arnawa.v1i1.11242.
Повний текст джерелаАнотація:
Pluralism is a cultural phenomenon that can be easily found in Indonesia. Cultural manifestations include ideas, traditions, and art that adorn the vast territory of Indonesia. Culture, in the form of tradition, is divided into oral tradition and written tradition. One of the manifestations of oral tradition is reflected in the Ki Sapu Jagad folklore, which is the background for the birth of the Labuhan Merapi tradition. Over time, this folklore was adapted by the people of Umbulharjo village in the form of performing arts as Labuhan Merapi Fragment. The Labuhan Merapi Fragment acts as a media novelty about the story of Ki Sapu Jagad. In addition, this fragment becomes an interesting thing for local people and tourists. This research aims to find out the existence, history, development, and inheritance of the Labuhan Merapi Fragment in all segments of society. Pertinent data were obtained through formal interviews and literature studies. The research method used is descriptive-qualitative. The data that has been collected is then processed with note-taking techniques. The implementation of the Labuhan Merapi Fragment is still routinely carried out from its inception to the present. This shows that the Labuhan Merapi Fragment is still sustainable and continues to be passed down continuously through the regeneration of performing arts presenters. With the existence of problems in efforts to maintain the existence of oral tradition, fragments of Labuhan Merapi still exist and have become the cultural identity of the people of Umbulharjo Village, Cangkringan District, Sleman Regency.
 ===
 Pluralisme merupakan fenomena kebudayaan yang dapat dijumpai dengan mudah di Indonesia. Wujud kebudayaan antara lain berupa gagasan, tradisi dan seni yang menghiasi luasnya wilayah Indonesia. Kebudayaan berupa tradisi terbagi atas tradisi lisan dan tradisi tulis. Perwujudan tradisi lisan salah satunya tercermin pada folklor Ki Sapu Jagad yang melatarbelakangi lahirnya tradisi Labuhan Merapi. Seiring berjalannya waktu, folklor ini diadaptasi oleh masyarakat Desa Umbulharjo dalam bentuk seni pertunjukan sebagai Fragmen Labuhan Merapi. Fragmen Labuhan Merapi berperan sebagai kebaruan media mengenai kisah Ki Sapu Jagad. Selain itu, fragmen ini menjadi sebuah hal yang menarik bagi masyarakat lokal dan para wisatawan. Penelitian ini bertujuan untuk mengetahui kesejarahan, perkembangan, peran serta pewarisan Fragmen Labuhan Merapi kepada seluruh segmentasi masyarakat. Data-data yang bersangkutan diperoleh melalui wawancara formal dan studi pustaka. Metode penelitian yang digunakan adalah deskriptif kualitatif. Data-data yang telah dikumpulkan kemudian diolah dengan teknik catat. Pelaksanaan Fragmen Labuhan Merapi masih secara rutin dilakukan dari awal terbentuknya hingga masa sekarang ini. Hal itu menunjukan bahwa Fragmen Labuhan Merapi masih lestari dan terus diwariskan secara kontinuitas melalui regenerasi penyaji seni pertunjukan. Dengan adanya problematika dalam usaha pemertahanan eksistensi tradisi lisan, Fragmen Labuhan Merapi tetap eksis dan menjadi identitas kebudayaan masyarakat Desa Umbulharjo, Kecamatan Cangkringan Kabupaten Sleman.
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Hu, Jie, Hua Chen, Yonggang Yu, Xiaochun Xue, Zhiwei Feng, and Xiaojun Chen. "Experimental Study on Motion Law of the Fragment at Hypersonic Speed." Processes 11, no. 4 (April 3, 2023): 1078. http://dx.doi.org/10.3390/pr11041078.
Повний текст джерелаАнотація:
As a damage element, high-speed fragments have a significant effect on the ammunition safety. The impact from the fragments are also one of the basic problems of ammunition safety tests. To clarify the reaction characteristics of combustion, explosion, detonation, and so on, when hypersonic fragments hit insensitive munitions, it is necessary to carry out corresponding research on the deceleration law of hypersonic fragment in the air. In this paper, a 30 mm caliber gun with large chamber, small caliber, and large aspect ratio is proposed to drive high-speed fragments. According to STANAG 4496 standard, a near-cylinder steel fragment with Brinell hardness HB ≤ 270 and mass of 18.6 g was designed. The test system was composed of zone interception velocity measurement, chamber pressure sensor, trajectory tracking system, high-speed camera, and other equipment were also established to obtain the pressure variations in the chamber, the velocity of the fragment, and its flight orientation. From the video taken by the high-speed camera and trajectory tracking system, the fragment and the projectile sabot achieve effective separation after the fragment travels out of the muzzle. As time goes on, the distance between the fragment and the projectile sabot gradually increases. The fragment is always in the front of the sabot and steadily flies to the target. The muzzle velocity of the fragment is controlled by adjusting the propellant charge, and the flight velocity in the air is measured by the zone interception velocity measuring device in the range of 5 Ma to 7 Ma. The theoretical models of fragment deceleration and the models of flight orientation are also established according to the experimental data. On this basis, F test and least square nonlinear regression fitting were used to analyze experimental data. Finally, the deceleration coefficient of quasi-cylindrical fragments between 5 Ma and 7 Ma stipulated in STANAG 4496 standard is 0.009312, and the average drag coefficient in air is 1.109.
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Johnson, Michael B. "Wrapping Up 1QM." Dead Sea Discoveries 30, no. 3 (December 13, 2023): 262–91. http://dx.doi.org/10.1163/15685179-bja10047.
Повний текст джерелаАнотація:
Abstract This article evaluates the debated placements of fragments in the reconstruction of the War Scroll from Cave 1 (1QM). There are three fragments (frags. 3, 9, 10) and one large fragment cluster (1QM 2, 8, DSSHU pl. 34; 1Q33 2) that are contested in 1QM scholarship. These placements are important for establishing the text of 1QM and the determination of whether there was another War Scroll from Cave 1 among the fragments assigned to 1QM and 1Q33. I will evaluate the remaining debates about fragment placements in 1QM, focusing especially on Hanan and Esther Eshel’s proposal (2000) that the large fragment cluster is not part of 1QM but is the remnant of a different scroll, which they label 1QMa. To assist in weighing the plausibility of fragment placements in 1QM, this article incorporates 3D visualizations of how 1QM would appear in a rolled state to demonstrate how well some proposed fragment placements cohere with the scroll’s damage patterns.
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Quinteiro, Tamara, José Lopes, and Ivan Carlos Fernandes Martins. "Diversidade de Carabidae (Coleoptera) Amostrados em Áreas de Reflorestamento de Mata Ciliar e Fragmento Florestal, no Estado do Paraná." EntomoBrasilis 5, no. 3 (December 12, 2012): 217–22. http://dx.doi.org/10.12741/ebrasilis.v5i3.255.
Повний текст джерелаАнотація:
Carabidae são Coleoptera com a maioria de suas espécies apresentando hábito alimentar predatório. O objetivo do presente trabalho foi estudar a diversidade e abundância da família Carabidae (Coleoptera) em áreas de fragmento florestal e em áreas de reflorestamento de mata ciliar, evidenciando a importância deste grupo como indicador da biodiversidade em relação ao sucesso do reflorestamento. Os besouros foram amostrados por meio de armadilhas de solo pitfall, em fragmentos florestais e reflorestamentos de mata ciliar em três municípios do estado do Paraná. A abundância de Carabidae foi maior nos reflorestamentos de mata ciliar. A espécie Odontochila nodicornis (Dejean) foi, significativamente, a mais abundante e encontrada em todas as áreas estudadas. Houve similaridade da riqueza de carabídeos encontrada no fragmento florestal remanescente com a riqueza constatadas nos reflorestamentos, mesmo naqueles onde as coletas foram realizadas distante 3 Km do fragmento ou nas áreas de reflorestamento que não apresentavam conexão com o fragmento remanescente. Tetracha brasiliensis (Kirby) foi coletado quase que exclusivamente no reflorestamento sem conexão com o fragmento. Utilizando-se o teste de Kruskal-Wallis, não se constatou atratividade pelas diferentes iscas, no entanto verificou-se diferença significativa entre o número coletado nas armadilhas com iscas, quando comparado com o controle. A maior concentração de carabídeos coletados foi no período de dezembro a fevereiro, estação correspondente ao verão para a região estudada. A similaridade da riqueza de carabídeos encontrada entre os fragmentos de floresta e os reflorestamentos de mata ciliar, pode sugerir sucesso do método de reflorestamento, estando avançando para condições de característica primária.
 Diversity of Carabidae (Coleoptera) Samples in Areas of Riparian Reforestation and Forest Fragment, in the State of Paraná
 Abstract. Carabidae are Coleoptera whose most species have a predatory eating habit. The purpose of this paper was to study the diversity and abundance of Carabidae (Coleoptera) family in forest fragment areas and in reforestation areas of riparian vegetation, evidencing the importance of this group as a biodiversity indicator regarding the reforestation success. Beetles were sampled using soil pitfall traps in forest fragments and reforestation of riparian vegetation in three municipalities the state of Parana. The abundance of Carabidae was higher in riparian reforestation. The species Odontochila nodicornis (Dejean) was the most significantly abundant and found in all studied areas. There was a similarity in richness of Carabidae found in the remaining forest fragment, being the wealth found in reforestation, even where samples were collected 3km away from the fragment or in reforestation areas that did not have any connection with the remaining fragment. Tetracha brasiliensis (Kirby) was almost exclusively collected in reforestation unrelated to the fragment. Using the Kruskal-Wallis test, it was not noted any attraction of different baits, but there was a significant difference between the collection number in baited traps compared with the control. The highest concentration of Carabidae was collected from December to February, period corresponding to the summer season for the studied region. The similarity on the richness of Carabidae found between forest fragments and reforestation of riparian vegetation may suggest the reforestation method success, being able to advance to the primary characteristic.
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Tian, Hui, and Jin Ping Ni. "Theoretical Research of Measuring the Kinetic Energy for Swarm of Fragments with Six-Light-Screen Array." Advanced Materials Research 468-471 (February 2012): 1326–29. http://dx.doi.org/10.4028/www.scientific.net/amr.468-471.1326.
Повний текст джерелаАнотація:
Aimed at the measurement of kinetic energy for swarm of flying fragments, a measuring method of kinetic energy for the flying fragment using six-light-screen array was presented in this paper. When a fragment pass through the six light screens, the six-time sequences, can be gathered in turn. Lots of fragments can generate some sequence of six-times. The algorithm that can distinguish the sequence from a group of sequences of time is put forward in this paper. According to the coordinates of fragment position on a position indicator as well as all the sequences of the fragments, the real time sequence can be distinguished and recognized. Then the real velocity and accurate location of the fragment can be calculated with the algorithm designed, and the kinetic energy of fragments can be measured. The algorithm is proved accurate and effective by the simulation.
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Lan, Yuzhen, Fang Wang, Tian Wang, and Cong Wang. "The influence of initiation methods on the fragmentation characteristics of axially enhanced warheads." Journal of Physics: Conference Series 2891, no. 9 (December 1, 2024): 092001. https://doi.org/10.1088/1742-6596/2891/9/092001.
Повний текст джерелаАнотація:
Abstract Based on Euler-Lagrange element coupling (CEL) simulation algorithm, this paper uses ABAQUS software to simulate and analyze the fragmentation of warhead under single point initiation, two-point initiation and four-point initiation. Simulation results show that the prefabricated fragment of the warhead can cover the target in the axial region completely. Regarding the velocity characteristics of the head fragments, tungsten-zirconium alloy and tungsten alloy fragments show different average velocities under different initiation modes. At four point initiation, the average velocity of tungsten-zirconium alloy fragments is 1371m/s, and the average velocity of tungsten alloy fragments is 1366m/s. At two point initiation, the average velocity of tungsten zirconium alloy fragment is 1351m/s, while the average velocity of tungsten alloy fragment is 1344m/s. When the single point initiation, the average speed of tungsten-zirconium alloy fragments is 1329m/s, and the average speed of tungsten alloy fragments is 1330m/s. The four-point initiation mode shows the highest axial fragment velocity, up to 1,848 m/s, while the single-point initiation mode has a maximum velocity of 1691m/s, a difference of about 150m/s. Secondly, with the increase of the flying angle, the fragment velocity will decrease accordingly. It can be seen that in the case of four-point initiation, the speed of the axial reinforcement fragment can be greatly increased, which can better solve the problem of the central blind area caused by the traditional killing warhead when striking the target, and achieve the coverage of the entire damage target area under the static explosion condition.
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Lundysheva, Olga. "Tocharian B Manuscripts in the Berezovsky Collection (2): Five More Fragments." Written Monuments of the Orient 5, no. 2 (December 15, 2019): 49–78. http://dx.doi.org/10.17816/wmo25893-.
Повний текст джерелаАнотація:
This article is a full edition of five Tocharian B manuscripts kept in the Berezovsky sub-collection of the Serindia Collection of the IOM, RAS: two Sanskrit-Tocharian В Bilingual Udānavarga fragments (Uv. 1.26b1.34a, Uv. 4.23b4.34c); a Sanskrit-Tocharian В Bilingual Karmavācanā (Upasaṃpadā) fragment, one fragment of a jātaka and one fragment of a stotra previously erroneously identified as Udānastotra. The article contains a transliteration, transcription, tentative translation as well as a commentary on the text of the fragments.
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Danielsen, C. C. "Thermal stability of human-fibroblast-collagenase-cleavage products of type-I and type-III collagens." Biochemical Journal 247, no. 3 (November 1, 1987): 725–29. http://dx.doi.org/10.1042/bj2470725.
Повний текст джерелаАнотація:
Rat skin type-I and type-III collagens were degraded by human fibroblast collagenase at a temperature below the ‘melting’ temperature for the two resulting fragments, namely the N-terminal three-fourths, TCA, and the C-terminal one-fourth, TCB. The specific cleavage of the collagen was confirmed by electrophoresis and determination of molecular length by electron microscopy. The two fragments were separated by gel filtration and the thermal stabilities of the isolated fragments were determined. For type-I collagen, the ‘melting’ temperatures of the two fragments were found to differ by only 0.5 degrees C and were 4.5-5.0 degrees C below that of the uncleaved molecule. The ‘melting’ temperatures of the uncleaved molecule and the N-terminal fragment were independent of the extent of N-terminal intramolecular cross-linking. For type-III collagen, the ‘melting’ temperatures of the fragments were found to differ by 1.3 degrees C. The small fragments of the two types of collagen ‘melted’ at the same temperature, whereas the large type-III fragment ‘melted’ at a slightly higher temperature than did the large type-I fragment. Reduction of the disulphide bonds located in the C-terminal type-III fragment did not affect the thermal stability of this fragment. The thermal stability of uncleaved type-III collagen was found to be variable, but the reason for this is not known at present.
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Shi, Yun, and Mark von Itzstein. "How Size Matters: Diversity for Fragment Library Design." Molecules 24, no. 15 (August 5, 2019): 2838. http://dx.doi.org/10.3390/molecules24152838.
Повний текст джерелаАнотація:
Fragment-based drug discovery (FBDD) has become a major strategy to derive novel lead candidates for various therapeutic targets, as it promises efficient exploration of chemical space by employing fragment-sized (MW < 300) compounds. One of the first challenges in implementing a FBDD approach is the design of a fragment library, and more specifically, the choice of its size and individual members. A diverse set of fragments is required to maximize the chances of discovering novel hit compounds. However, the exact diversity of a certain collection of fragments remains underdefined, which hinders direct comparisons among different selections of fragments. Based on structural fingerprints, we herein introduced quantitative metrics for the structural diversity of fragment libraries. Structures of commercially available fragments were retrieved from the ZINC database, from which libraries with sizes ranging from 100 to 100,000 compounds were selected. The selected libraries were evaluated and compared quantitatively, resulting in interesting size-diversity relationships. Our results demonstrated that while library size does matter for its diversity, there exists an optimal size for structural diversity. It is also suggested that such quantitative measures can guide the design of diverse fragment libraries under different circumstances.
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Yang, Jiang-Yan, and Christian Widmann. "Antiapoptotic Signaling Generated by Caspase-Induced Cleavage of RasGAP." Molecular and Cellular Biology 21, no. 16 (August 15, 2001): 5346–58. http://dx.doi.org/10.1128/mcb.21.16.5346-5358.2001.
Повний текст джерелаАнотація:
ABSTRACT Activation of caspases 3 and 9 is thought to commit a cell irreversibly to apoptosis. There are, however, several documented situations (e.g., during erythroblast differentiation) in which caspases are activated and caspase substrates are cleaved with no associated apoptotic response. Why the cleavage of caspase substrates leads to cell death in certain cases but not in others is unclear. One possibility is that some caspase substrates generate antiapoptotic signals when cleaved. Here we show that RasGAP is one such protein. Caspases cleave RasGAP into a C-terminal fragment (fragment C) and an N-terminal fragment (fragment N). Fragment C expressed alone induces apoptosis, but this effect could be totally blocked by fragment N. Fragment N could also block apoptosis induced by low levels of caspase 9. As caspase activity increases, fragment N is further cleaved into fragments N1 and N2. Apoptosis induced by high levels of caspase 9 or by cisplatin was strongly potentiated by fragment N1 or N2 but not by fragment N. The present study supports a model in which RasGAP functions as a sensor of caspase activity to determine whether or not a cell should survive. When caspases are mildly activated, the partial cleavage of RasGAP protects cells from apoptosis. When caspase activity reaches levels that allow completion of RasGAP cleavage, the resulting RasGAP fragments turn into potent proapoptotic molecules.
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Hermanto, Bambang. "The Growht of Acropora Formosa Fragment in Different Sizes Using Transplantation Method in Lembeh Strait." JURNAL ILMIAH PLATAX 3, no. 2 (February 16, 2016): 90. http://dx.doi.org/10.35800/jip.3.2.2015.13224.
Повний текст джерелаАнотація:
Transplantation method is an effective way for rehabilitating the degraded coral reef. Acropora formosa is one of the coral species that is used for transplantation method which is a kind of branching corals that have a rapid growth up to 8 cm/year. This study aimed to determine the effect of coral fragment size to the coral growth, survival rate and the growth rate of Acropora formosa at several locations in the Lembeh Strait. The research was conducted in February - June 2015 using concrete block transplantation method. The results showed that Acropora formosa with the initial fragment length 8 cm have the highest of survival rates (84 %), absolute growth (0,8 cm) and growth rate (0,201 cm/month). The initial fragments length of Acropora formosa can affect the coral growth in transplantation method (p <0.05). Keywords: Coral transplantation, Acropora formosa, Fragment size, North Sulawesi ABSTRAK Metode transplantasi merupakan metode yang cukup efektif untuk merehabilitasi kondisi terumbu karang yang mengalami degradasi. Salah satu jenis yang sering digunakan untuk metode transplantasi yaitu jenis Acropora formosa yang merupakan jenis karang bercabang yang memiliki pertumbuhan yang cukup cepat hingga 8 cm/tahun. Penelitian ini bertujuan untuk mengetahui pengaruh ukuran fragmen terhadap pertumbuhan karang, tingkat kelangsungan hidup serta laju pertumbuhan fragmen karang Acropora formosa pada beberapa lokasi di perairan Selat Lembeh. Penelitian dilakukan pada bulan Februari - Juni 2015 dengan menggunakan metode transplantasi lepas dasar (substrat beton). Hasil penelitian menunjukkan bahwa fragmen karang Acropora formosa dengan panjang fragmen awal 8 cm memiliki tingkat kelangsungan hidup, pertumbuhan mutlak dan laju pertumbuhan tertinggi yaitu mencapai 84% (survival rate), 0,8 cm (pertumbuhan mutlak tinggi) dan 0,201 cm/bln (laju pertumbuhan). Ukuran panjang awal fragmen Acropora formosa cukup berpengaruh terhadap pertumbuhan karang (p<0,05). Kata kunci: Transplantasi karang, Acropora formosa, ukuran fragmen, Sulawesi Utara
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Peng, Jun, Wei Liu, Zheng-feng Liang, and Hong-fu Guo. "Experimental Study on the Effect of Buffer Layer on the Explosive Drive of Reactive Fragment." Journal of Physics: Conference Series 2478, no. 3 (June 1, 2023): 032091. http://dx.doi.org/10.1088/1742-6596/2478/3/032091.
Повний текст джерелаАнотація:
Abstract In order to study the influence of the buffer layer on the explosive drive of the reactive fragment, for the reactive fragment warhead of the same structure, the warhead static explosion test and the break-through target test method were used to test the fragment integrity and the fragment integrity of the reactive fragment warhead of the reactive fragment warhead with several different thickness silicone rubber buffer layers. The initial velocity of the fragment was measured, and its integrity and the variation law of the initial velocity were analyzed. The results show that with the increase of the thickness of the buffer layer, the integrity of the reactive fragments increases. When the thickness of the buffer layer is 2 mm, the fragment integrity rate is zero, and when the thickness of the buffer layer is greater than 8 mm, the integrity rate is greater than 0.85. The difference in the initial velocity of the warhead of the same reactive fragment is small, mainly because with the increase of the thickness of the buffer layer, the initial velocity of the fragment decreases mainly because the loading ratio of the warhead decreases; the buffer layer has a significant effect on reducing the initial velocity of the reactive fragment, and k=0.83 can be used The modified Gurney formula was used to estimate the initial velocity of the reactive fragments of the silicone rubber buffer layer.
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Messent, A. J., D. S. Tuckwell, V. Knauper, M. J. Humphries, G. Murphy, and J. Gavrilovic. "Effects of collagenase-cleavage of type I collagen on alpha2beta1 integrin-mediated cell adhesion." Journal of Cell Science 111, no. 8 (April 15, 1998): 1127–35. http://dx.doi.org/10.1242/jcs.111.8.1127.
Повний текст джерелаАнотація:
In this paper we show that collagenase-3 cleavage of type I collagen has a marked effect on alpha2beta1 integrin-mediated interactions with the collagen fragments generated. Isolated alpha2beta1 integrin and alpha2 integrin A-domain were found to bind to both native collagen and native 3/4 fragment and, to a lesser degree, native 1/4 fragment. Whole integrin and integrin A-domain binding were lost after heat denaturation of the collagen fragments. At physiological temperature, cell adhesion to triple-helical 3/4 fragment via alpha2beta1 integrin was still possible; however, no alpha2beta1 integrin-mediated adhesion to the 1/4 fragment was observed. Unwinding of the collagen fragment triple helices by heating to physiological temperatures prior to adsorption to plastic tissue culture plates resulted in total abrogation of HT1080 cell attachment to either fragment. These results provide significant evidence in support of a role for matrix-metalloproteinase cleavage of the extracellular matrix in modifying cell-matrix interactions.
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MADELEY, N. J., A. B. STEPHEN, N. D. DOWNING, and T. R. C. DAVIS. "Changes in Scaphoid Bone Density after Acute Fracture." Journal of Hand Surgery 31, no. 4 (August 2006): 368–70. http://dx.doi.org/10.1016/j.jhsb.2006.03.164.
Повний текст джерелаАнотація:
The radiographic density of the proximal fragments of 16 scaphoid fractures was assessed on scaphoid series radiographs taken at 6 to 12 weeks. In addition, dual energy X-ray absorptiometry measurements of bone mineral density in the distal radius and proximal and distal fracture fragments were performed at 1 to 2 weeks and 6 to 12 weeks. Median reductions of 9% and 10% were observed in bone mineral density in the proximal fracture fragment and the distal radius respectively, but these did not correlate with the radiographic density of the proximal fragment. A greater median reduction in bone mineral density (27%) was observed in the distal fracture fragment and more bone loss occurred at this site when there was an apparent increase in the radiographic density of the proximal fragment (median fall of 0.23 g/cm2 versus 0.14 g/cm2). Thus, apparent increased radiographic density of the proximal fragment may be due to increased bone loss from the distal fragment.
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MA, Yue, Yong HE, Chuanting WANG, Yuan HE, and Lei GUO. "Response behavior of double layer tungsten fragments under detonation loading." Xibei Gongye Daxue Xuebao/Journal of Northwestern Polytechnical University 40, no. 4 (August 2022): 819–28. http://dx.doi.org/10.1051/jnwpu/20224040819.
Повний текст джерелаАнотація:
Under detonation loading, the prefabricated fragments in the warhead will be greatly deformed and even broken. In order to explore the model of deformation, the dynamic response of double-layer spherical tungsten fragments under detonation loading was studied. Firstly, a typical cylindrical warhead model was numerically simulated. The simulation model for the characteristic section only includes the quarter model for the double row fragments in the axial direction, in order to obtain the deformation response of the fragments under the detonation loading. The full-size 1/4 simulation model is designed to obtain the axial velocity distribution of the fragment. In the characteristic section, the charge diameter was used as the variable to simulate five charge sizes, and the fragment deformation law was obtained. In order to verify the correctness of the simulation, the warhead of 400 mm caliber was tested, and the flight speed of the fragment was measured. Some deformed fragments were obtained by soft recovery and their cross-section microstructure were analyzed by scanning electron microscope (SEM). The results show that the deformation of the inner layer of the double-layer spherical tungsten alloy fragment is more serious under the action of the internal explosion load, because it is squeezed by the internal explosion load and the outer layer fragment at the same time. The final dispersion velocities of the inner and outer fragments tend to be the same, and there is no significant difference in the distribution of fragments.