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Статті в журналах з теми "Flavophospholipol"

Автор: Grafiati
Опубліковано: 4 червня 2021
Оновлено: 15 лютого 2022

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1

Spergser, J., Karin Zitterl-Eglseer, Cornelia Gabler-Eduardo, F. Schilcher, Astrid Bucher, M. Schuh, J. Troxler, Ch Franz, and Martina Jugl-Chizzola. "Untersuchungen zur Wirkung von Galakturoniden als Futtermittelzusatz im Vergleich zum Leistungsförderer Flavophospholipol und einer Kontrollgruppe bei Absetzferkeln." Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere 32, no. 03 (2004): 147–54. http://dx.doi.org/10.1055/s-0038-1623549.

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Zusammenfassung Gegenstand und Fragestellung: Untersuchungen zur Wirkung von Galakturoniden als Futtermittelzusatz im Vergleich zum Leistungsförderer Flavophospholipol und einer Kontrollgruppe bei Absetzferkeln. Material und Methoden: In einer Fütterungsstudie wurden Galakturonide als Futterzusatz im Vergleich zu Flavophospholipol in der Ferkelaufzucht getestet (Galakturonide: 10 g bzw. 5 g/kg Futter, Flavophospholipol: 10 mg/kg Futter). Die Ferkel erhielten drei Tage vor bis 27 Tage nach dem Absetzen die verschiedenen Futterzusätze oder keinerlei Futterzusatz. Den Futterrationen der Gruppe 1 (n = 42) wurden Galakturonide, der Gruppe 3 (n = 42) Flavophospholipol und der Gruppe 2 (n = 40) kein derartiger Futterzusatz beigefügt. Von allen Ferkeln wurden rektale Kottupferproben in drei- bis siebentägigen Intervallen genommen und einer mikrobiologischen Untersuchung unterzogen. Ergebnisse: Bezüglich bakteriologischer Untersuchungsergebnisse (Inzidenz von hämolysierenden pathogenen E. coli, Serotypen, Antibiogramme), der Lebendmassezunahme und des Futteraufwandes ergaben sich keine signifikanten Unterschiede zwischen den verschiedenen Gruppen. Ein- bis mehrfach resistente hämolysierende E. coli wurden von Absetzferkeln aller Gruppen ausgeschieden. Schlussfolgerung: Die weitere Untersuchung von aus Pflanzen gewonnenen Futterzusätzen ist sinnvoll.
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2

van den Bogaard, A. E., M. Hazen, M. Hoyer, P. Oostenbach, and E. E. Stobberingh. "Effects of Flavophospholipol on Resistance in Fecal Escherichia coli and Enterococci of Fattening P." Antimicrobial Agents and Chemotherapy 46, no. 1 (January 2002): 110–18. http://dx.doi.org/10.1128/aac.46.1.110-118.2002.

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ABSTRACT A “plasmid-curing effect” of multiresistant Escherichia coli by flavophospholipol, an antibiotic used as an antimicrobial growth promoter (AMGP) in animal feeds, has been reported to occur in vitro and in vivo under experimental conditions. In this study, the effect of flavophospholipol under field conditions was studied. The prevalence and degree (proportion of resistant strains to the total numbers present per gram of feces) of resistance of indicator bacteria, E. coli and enterococci, was determined in fecal samples from three groups of pigs that were fed a commercial finisher feed without any AMGP. Group A was the negative control group without any AMGP, group B received the same feed with 9 mg of flavophospholipol/kg of feed (study group), and group C received the same feed with 15 mg of avoparcin/kg (positive control). Fecal samples from each pig were collected at the start and at the end of the study and assessed for the prevalence and degree of resistance against antibiotics commonly used either for therapy in pig medicine or as an AMGP. Before the start of the study, all pigs were colonized with multiresistant E. coli by mixing three resistant pig isolates through their feed after disturbance of the colonization resistance of the intestinal flora by a 3-day course of lincomycin and spectinomycin. At the end of the study, the overall prevalence and degree of resistance of E. coli in the fecal flora had increased significantly in groups A and C but remained at the same level as at the start of the study in group B. The prevalence of vancomycin resistance was 44 and 41% in groups A and B, respectively, but only very low numbers of vancomycin-resistant enterococci (VRE) per gram of feces were found. In the avoparcin-fed group, the prevalence was 72%, and in 57% of the samples, more than 50% of all enterococci present were vancomycin resistant. The prevalence of resistant Enterococcus faecalis increased only in the flavophospholipol-exposed group, from 23% before the start of the study to 43% at the end of the study. It was concluded that flavophospholipol effectively suppressed the augmentation and dissemination of multiresistant E. coli in the intestinal flora of fattening pigs. Avoparcin use strongly selected for VRE carriage and excretion. Therefore, as neither flavophospholipol nor any related molecule is used therapeutically, no cross-resistance with therapeutic antibiotics exists and no transmissible resistance has been shown; the major decrease in resistance in intestinal E. coli of flavophospholipol-fed animals seemed to outweigh the small increase in the risk of transfer of flavophospholipol-resistant E. faecalis from animals to humans via the food chain.
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3

Barros, Rafael de, Sergio Luiz Vieira, André Favero, Diogo Taschetto, Natacha Camilotti Mascarello, and Henrique Scher Cemin. "Reassessing flavophospholipol effects on broiler performance." Revista Brasileira de Zootecnia 41, no. 12 (December 2012): 2458–62. http://dx.doi.org/10.1590/s1516-35982012001200011.

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4

Riedl, Sabine, Knut Ohlsen, Guido Werner, Wolfgang Witte, and Jörg Hacker. "Impact of Flavophospholipol and Vancomycin on Conjugational Transfer of Vancomycin Resistance Plasmids." Antimicrobial Agents and Chemotherapy 44, no. 11 (November 1, 2000): 3189–92. http://dx.doi.org/10.1128/aac.44.11.3189-3192.2000.

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ABSTRACT The influence of vancomycin and flavophospholipol (FPL) on the transfer rate of conjugative plasmids harboring the vancomycin resistance operon vanA was determined in several clinical and animal isolates of Enterococcus faecium. FPL significantly inhibited the frequency of transfer of conjugative VanA plasmids up to 70-fold. Vancomycin had no significant effect on the transfer rate of VanA plasmids.
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5

Riedel, G., H. Reiter, and U. Lösch. "Die Auswirkungen oraler Flavophospholipol-(FPL-)Gaben auf das Wachstum keimfreier Küken1." Zeitschrift für Tierphysiologie Tierernährung und Futtermittelkunde 32, no. 1-5 (October 9, 2009): 328–34. http://dx.doi.org/10.1111/j.1439-0396.1973.tb00394.x.

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6

Fébel, Hedvig, S. Fekete, and R. Romvári. "Comparative investigation of Salinomycin and flavophospholipol in sheep fed different composed diets." Archiv für Tierernaehrung 54, no. 3 (July 2001): 225–42. http://dx.doi.org/10.1080/17450390109381980.

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7

Torok, Valeria A., Gwen E. Allison, Nigel J. Percy, Kathy Ophel-Keller, and Robert J. Hughes. "Influence of Antimicrobial Feed Additives on Broiler Commensal Posthatch Gut Microbiota Development and Performance." Applied and Environmental Microbiology 77, no. 10 (March 25, 2011): 3380–90. http://dx.doi.org/10.1128/aem.02300-10.

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ABSTRACTThe effects of avilamycin, zinc bacitracin, and flavophospholipol on broiler gut microbial community colonization and bird performance in the first 17 days posthatch were investigated. Significant differences in gut microbiota associated with gut section, dietary treatment, and age were identified by terminal restriction fragment length polymorphism (T-RFLP), although no performance-related differences between dietary treatments were detected. Similar age-related shifts in the gut microbiota were identified regardless of diet but varied between the ilea and ceca. Interbird variabilities in ileal bacterial communities were reduced (3 to 7 days posthatch) in chicks fed with feed containing antimicrobial agents. Avilamycin and flavophospholipol had the most consistent effect on gut microbial communities. Operational taxonomic units (OTU) linked to changes in gut microbiota in birds on antimicrobial-supplemented diets were characterized and identified. Some OTUs could be identified to the species level; however, the majority could be only tentatively classified to the genus, family, order, or domain level. OTUs 140 to 146 (Lachnospiraceae), OTU 186/188 (Lactobacillus johnsonii), OTU 220 (Lachnospiraceae), OTUs 284 to 288 (unclassified bacterial spp. orRuminococcaceae), OTU 296/298 (unclassified bacterium orClostridiales), and OTU 480/482 (Oxalobacteraceae) were less prevalent in the guts of chicks fed antimicrobial-supplemented diets. OTU 178/180 (Lactobacillus crispatus), OTU 152 (Lactobacillus reuterior unclassifiedClostridiales), OTU 198/200 (Subdoligranulumspp.), and OTU 490/492 (unclassified bacterium orEnterobacteriaceae) were less prevalent in the gut of chicks raised on the antimicrobial-free diet. The identification of key bacterial species influenced by antimicrobial-supplemented feed immediately posthatch may assist in the formulation of diets that facilitate beneficial gut microbial colonization and, hence, the development of alternatives to current antimicrobial agents in feed for sustainable poultry production.
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8

Bustos, Patricio, and Carlos Covarrubias. "The effect of oral administration of flavophospholipol in rainbow trout (Oncorhynchus mykiss) fingerlings." Aquaculture 124, no. 1-4 (July 1994): 359–60. http://dx.doi.org/10.1016/0044-8486(94)90410-3.

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9

Pfaller, Michael A. "Flavophospholipol use in animals: Positive implications for antimicrobial resistance based on its microbiologic properties." Diagnostic Microbiology and Infectious Disease 56, no. 2 (October 2006): 115–21. http://dx.doi.org/10.1016/j.diagmicrobio.2006.03.014.

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10

Kudo, Hayami, Masaru Usui, Wataru Nagafuji, Kentaro Oka, Motomichi Takahashi, Hiroyuki Yamaguchi та Yutaka Tamura. "Inhibition effect of flavophospholipol on conjugative transfer of the extended-spectrum β-lactamase and vanA genes". Journal of Antibiotics 72, № 2 (25 жовтня 2018): 79–85. http://dx.doi.org/10.1038/s41429-018-0113-4.

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11

Valchev, G. "Organic acids in combined forages for growing pigs." Biotehnologija u stocarstvu 24, no. 3-4 (2008): 121–28. http://dx.doi.org/10.2298/bah0804121v.

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The purpose of this paper is to determine the effect of replacement of nutritive antibiotics in compound feed for starter pigs with acidifier Acid Lac as growth promoters. Acid Lac is a new generation acidifier a combination of appropriately selected organic acids - Fumaric, Propionic, Citric, Formic and Lactic acids, with pronounced anti-bacterial effect. Two experiments were carried out with total of 126 growing pigs from 6 to 20kg live weight to determine the effect of organic acids as growth promoters. The results of these experiments show that acidifying of feed for growing pigs with product Acid Lac in doses 0.3 and/or 0.5 percent, improves the average daily gain from 7 to 9 per cent, and better feed efficiency from 8 to 13 percent (P<0.05), decrease the number of pathogenic and relative-pathogenic microorganisms, compared to pigs with or without nutritive antibiotics Flavophospholipol in combined feed. Under the present investigation might be concluded that organic acids could be successfully used as growth stimulators, replacing nutritive antibiotics in pig diets.
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12

Poole, T. L. "Effect of flavophospholipol on conjugation frequency between Escherichia coli donor and recipient pairs in vitro and in the chicken gastrointestinal tract." Journal of Antimicrobial Chemotherapy 58, no. 2 (May 30, 2006): 359–66. http://dx.doi.org/10.1093/jac/dkl249.

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13

Bahrampour, K., M. Afsharmanesh, and M. Khajeh Bami. "Comparative effects of dietary Bacillus subtilis, Bacillus coagulans and Flavophospholipol supplements on growth performance, intestinal microflora and jejunal morphology of Japanese quail." Livestock Science 239 (September 2020): 104089. http://dx.doi.org/10.1016/j.livsci.2020.104089.

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14

Bolder, NM, JA Wagenaar, FF Putirulan, KT Veldman, and M. Sommer. "The effect of flavophospholipol (Flavomycin) and salinomycin sodium (Sacox) on the excretion of Clostridium perfringens, Salmonella enteritidis, and Campylobacter jejuni in broilers after experimental infection." Poultry Science 78, no. 12 (December 1999): 1681–89. http://dx.doi.org/10.1093/ps/78.12.1681.

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15

Javandel, Faramin, Mehran Nosrati, René van den Hoven, Alireza Seidavi, Vito Laudadio, and Vincenzo Tufarelli. "Effects of Hogweed (Heracleum persicum) Powder, Flavophospholipol, and Probiotics as Feed Supplements on the Performance, Carcass and Blood Characteristics, Intestinal Microflora, and Immune Response in Broilers." Journal of Poultry Science 56, no. 4 (2019): 262–69. http://dx.doi.org/10.2141/jpsa.0180081.

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16

Dehghani, Naghmeh, Mohsen Afsharmanesh, Mohammad Salarmoini, and Hadi Ebrahimnejad. "In vitro and in vivo evaluation of thyme (Thymus vulgaris) essential oil as an alternative for antibiotic in quail diet1." Journal of Animal Science 97, no. 7 (May 22, 2019): 2901–13. http://dx.doi.org/10.1093/jas/skz179.

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Abstract The thyme (Thymus vulgaris) essential oil was assessed as antibiotic growth promoter replacement in quail chick diet and in vitro test. In total, 250-d-old Japanese quail chicks (mixed sex) were allocated into 5 dietary treatments of 5 replications (6 females and 4 males in each cage with the size of 40× 90× 25 cm) under a completely randomized design. The dietary treatments were included the control diet, control diet without any additive, control diet plus 100 ppm flavophospholipol as an antibiotic growth promoter, control diet plus 200 ppm TVE, control diet plus 300 ppm TVE, and control diet plus 400 ppm T. vulgaris essential (TVE) oil. Feed intake, BW gain, feed conversion ratio (FCR), organs weight, morphology of intestine, serum lipids, and microbial population were measured on day 35. Lipid oxidation of stored muscle tissue was measured by TBARS test. GC–MS assay, DPPH method, and well diffusion method were evaluated for determination of components, antioxidant, and antimicrobial properties, respectively. FCR improved significantly in 400 ppm TVE compared with 200 and 300 ppm TVE (P < 0.05). The serum triglyceride decreased significantly in both sexes receiving 400 ppm TVE compared with control. Villi height increased significantly in duodenum accompanied by decreasing crypt dept at all TVE levels compared with control and antibiotic. The breast muscle tissue of quail fed on 300 and 400 ppm TVE reduced the rate of oxidation during refrigerated storage compared with control. Thymol was the main component (35.40%) of the thymus oil. The considerable antioxidant activity of TVE was identified by IC50 of 58.48 µg/mL. Moreover, zones of growth inhibition of Gram-positive bacteria and Escherichia coli were numerically greater in different doses of TVE than antibiotics. Therefore, The TVE is suitable alternative component for antibiotic growth promoters by dosing consideration. However, it is possible that antibiotic resistance would increase for these natural compounds along the time.
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17

Lim, Kelvin, Michael Pennell, Stephanie Lewis, Mohamed El-Gazzar, and Wondwossen A. Gebreyes. "Effects of flavophospholipol on conjugation and plasmid curing of multidrug-resistant Salmonella Enteritidis in broiler chickens." JAC-Antimicrobial Resistance 3, no. 1 (January 18, 2021). http://dx.doi.org/10.1093/jacamr/dlab022.

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Abstract Background Early in vitro studies suggested that flavophospholipol has plasmid-curing effects and could inhibit conjugation by disrupting pilus formation between bacteria. Objectives This 36-day controlled-challenge study aimed to evaluate the anti-conjugative and plasmid-curing effect of flavophospholipol in vivo on plasmid-mediated antimicrobial resistance (AMR) in MDR transconjugant Salmonella Enteritidis in chickens. Methods A total of 270-day-old chicks were randomly assigned to four control and four treatment groups with two doses of in-feed flavophospholipol (10 ppm and 64 ppm) and in the presence and absence of ampicillin in drinking water. Chicks were orally challenged with Salmonella Enteritidis with known plasmid-encoded AMR factors. Cloacal swabs were collected on Day 7, 14 and 23. On Day 35, all chickens were euthanized, and caecal tissue and content were collected. Antimicrobial susceptibility testing was done with a panel of 12 antimicrobials and interpreted according to CLSI breakpoints. Results Flavophospholipol given in-feed at 64 ppm had an anti-conjugative effect. There was a significant reduction of acquisition of resistance to ampicillin, streptomycin and tetracycline by the recipient strains of Salmonella Enteritidis in treatment groups given flavophospholipol in-feed at 64 ppm (P &lt; 0.05). This was not seen with flavophospholipol given in-feed at 10 ppm. Conclusions The results demonstrate that flavophospholipol given in-feed at 64 ppm had an anti-conjugative effect. The results also suggest that AMR is reduced through other mechanisms of action, which are yet to be determined. There is insufficient evidence that flavophospholipol at 64 ppm in feed alone or with sub-therapeutic levels of antibiotics had a plasmid-curing effect.
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18

Nair, Saranya, Abdolvahab Farzan, J. Scott Weese, Zvonimir Poljak, and Robert M. Friendship. "Effect of flavophospholipol on fecal microbiota in weaned pigs challenged with Salmonella Typhimurium." Porcine Health Management 6, no. 1 (May 12, 2020). http://dx.doi.org/10.1186/s40813-020-00151-5.

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19

Shamsi, S., A. Seidavi, M. Rahati, and JA Nieto. "Edible mushroom powder (Agaricus bisporus) and flavophospholipol improve performance and blood parameters of broilers." Revista Colombiana de Ciencias Pecuarias 28, no. 4 (October 2, 2015). http://dx.doi.org/10.17533/udea.rccp.v28n4a01.

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20

Van der Merwe, B. J., T. J. Dugmore, and K. P. Walsh. "The effect of flavophospholipol (Flavomycin ®) on milk production and milk urea nitrogen concentrations of grazing dairy cows." South African Journal of Animal Science 31, no. 2 (February 1, 2001). http://dx.doi.org/10.4314/sajas.v31i2.3835.

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