Добірка наукової літератури з теми "Feasibility studies Australia"

The Physician Asthma Care Education (PACE) program significantly improved asthma prescribing and communication behaviours of primary care paediatricians in the USA. We tested the feasibility and acceptability of a modified PACE program with Australian general practitioners (GP) and measured its impact on self-reported consulting behaviours in a pilot study. Recruitment took place through a local GP division. Twenty-five GP completed two PACE Australia workshops, which incorporated paediatric asthma management consistent with Australian asthma guidelines and focussed on effective communication strategies. Program feasibility, usefulness and perceived benefit were measured by questionnaires before the workshop and 1 month later, and an evaluation questionnaire after each workshop. GP were universally enthusiastic and supportive of the workshops. The most useful elements they reported were communication skills, case studies, device demonstrations and the toolkit provided. GP self reports of the perceived helpfulness of the key communication strategies and their confidence in their application and reported frequency of use increased significantly after the workshops. The PACE program shows promise in improving the way in which Australian GP manage asthma consultations, particularly with regard to doctor–patient communication. The impact of the modified PACE Australia program on the processes and outcomes of GP care of children with asthma is now being measured in a randomised controlled trial.

The Australian prefabricated construction market has been developing rapidly in recent years. New prefabrication-related technologies, materials, systems and services are also emerging in the current Australian market. Although some studies have been undertaken to explore the benefits and challenges of implementing prefabrication in Australia over the past 15 years, they do not reflect the recent changes in the industry. Therefore, this study aims to fill this gap and identify the major changes in the current Australian prefabricated construction industry from industrial perceptions. Through literature reviews and industry interviews, factors reflecting major changes in the current Australian prefabricated construction, including prefabrication industry development, emerging benefits and challenges, were identified and discussed in this study. The challenges identified from interviews were classified into eight aspects related to feasibility, design, manufacturing, transportation, on-site construction, standardisation, skills and knowledge, finance and market. Furthermore, 21 recommendations and related key responsible parties were identified to tackle these challenges. The findings will provide useful references for various stakeholders to have a better understanding of the current prefabrication industry development in the Australian context and re-think how to adapt to future changes for the uptake of prefabricated construction in Australia.

Bitou bush (Chrysanthemoides monilifera subsp. rotundata) is a Weed of National Significance in Australia and has impacted a significant portion of the eastern coastline. Its discovery in Western Australia was, therefore, a cause for concern. Assessment and control of the isolated and well-defined population began in 2012. To assess the feasibility of eradication in Western Australia as a management outcome for bitou bush, we applied a rigorous data-driven quantification and prediction process to the control program. Between 2012 and 2018 we surveyed over 253 ha of land and removed 1766 bitou bush plants. Approximately 97 person-days were spent over the six years of survey. We measured the seed bank viability for five years starting in 2013, with the 2017 survey results indicating a decline of mean viable seeds/m2 from 39.3 ± 11.4 to 5.7 ± 2.2. In 2018 we found only ten plants and no newly recruited seedlings in the population. No spread to other areas has been recorded. Soil core studies indicate that the soil seed bank is unlikely to persist beyond eight years. Eradication of the population in Western Australia, defined as five years without plants being detected, therefore remains a realistic management goal. The information generated from the documentation of this eradication program provides invaluable insight for weed eradication attempts more generally: novel detection methods can be effective in making surveys more efficient, all survey methods are not entirely accurate and large plants can escape detection, bitou bush seeds persist in the soil but become effectively undetectable at low densities, and migration of seed was unquantifiable, possibly compromising delimitation. Continued monitoring of the Western Australian population will determine how much of a risk these factors represent to eradication as the outcome of this management program.

This paper reports on field agronomy studies into flax (Linum usitatissimum L.) conducted in Tasmania, Australia from 1994 to 1997. These studies investigated the performance of selected cultivars, and responses to sowing date, plant density and irrigation. The work formed part of a feasibility study assessing the potential of fibre hemp (Cannabis sativa L.) and flax as sources of fibre for the Australian newsprint industry. Two cultivar evaluation trials were conducted at the University of Tasmania Farm, Cambridge, in Tasmania’s south-east. One of these included 7 European and Australian flax cultivars, and the other, 4 mucilage linseed cultivars. The European flax cultivars yielded significantly more stem and bark fibre than the Australian flax cultivars. Of the former group, Ariane (841 g/m 2 ) and Marina (883 g/m 2 ) performed the best in terms of stem yield production, while Viking had comparable bark yields to these 2 cultivars. With the exception of cv. Kreola (543 g/m 2 ), which produced comparable stem yields to the Australian flax cultivars, the linseed cultivars were short and produced relatively low stem yields. Interestingly, seed yields (149–194 g/m 2 ) were not superior to those for the flax cultivars (156–218 g/m 2 ). While offering little dual-purpose seed/fibre potential, they may supply a future niche market for seed production. Three other trials were conducted to investigate the response of flax to seeding rate and sowing date, and the interactions between seeding rate, sowing date and irrigation availability. Autumn sowings of flax gave higher yields of both stem and seed compared with winter and spring sowings. Reasonable stem and seed yields were achieved from dryland cropping of flax. However, good results from such rainfed crops in Tasmania will depend on autumn sowing and good rainfall during winter and spring seasons. There were clear yield benefits from irrigation between early November and January, when the amount and distribution of rainfall was poor. The selection of an optimum seeding rate will depend on the sowing date and involve a compromise between maximising yield and minimising potential losses from lodging. The decreased occurrence of lodging with winter and spring sowings in this study, suggests that later sowings can accommodate higher seeding rates.

ABSTRACTA recent trend throughout Australia has been to develop multi-purpose indoor public aquatic centres in favour of outdoor pools. Such major policy and planning decisions often rely on consultants' feasibility studies, yet there is limited comprehensive industry-wide data available on which to base such decisions. The industry-wide performance measures discussed in this paper help fill this void by providing objective data to support the contention that multi-purpose indoor aquatic centres tend to outperform centres with solely outdoor pools. The key indicators of performance are based on financial viability and community participation data for a sample of Australian public aquatic centres.

ABSTRACTA recent trend throughout Australia has been to develop multi-purpose indoor public aquatic centres in favour of outdoor pools. Such major policy and planning decisions often rely on consultants' feasibility studies, yet there is limited comprehensive industry-wide data available on which to base such decisions. The industry-wide performance measures discussed in this paper help fill this void by providing objective data to support the contention that multi-purpose indoor aquatic centres tend to outperform centres with solely outdoor pools. The key indicators of performance are based on financial viability and community participation data for a sample of Australian public aquatic centres.

Alcohol and other drug (AoD) use is an important health and community issue and may be positively affected by collaborative care programs between specialist AoD services and general practice. This paper describes the feasibility, model of care and patient outcomes of a pilot general practice and specialist AoD (GP-AoD) collaborative care program, in Sydney, Australia, based on usual care data, the minimum data set, service utilisation information and the Australian Treatment Outcome Profile (ATOP), a patient-reported outcome measure. There were 367 referrals to the collaborative care program. GPs referred 210 patients, whereas the AoD service referred 157 patients. Most GP referrals (91.9%) were for AoD problems, whereas nearly half the AoD service referrals were for other issues. The primary drugs of concern in the GP group were either opioids or non-opioids (mostly alcohol). The AoD service-referred patients were primarily using opioids. An ATOP was completed for 152 patients. At the time of referral, those in the GP-referred non-opioid group were significantly less likely to be abstinent, used their primary drug of concern more days and were more likely to be employed (all P < 0.001). A second ATOP was completed for 93 patients. These data showed a significant improvement in the number of days the primary drug of concern was used (P = 0.026) and trends towards abstinence, improved quality of life and physical and psychological well-being for patients in the program. There are few studies of GP-AoD collaborative care programs and nothing in the Australian context. This study suggests that GP-AoD collaborative care programs in Australia are feasible and improve drug use.

Three tree species from the genus Melaleuca are being examined for use in constructed wetlands in subtropical SE Queensland, Australia. Growth responses of Melaleuca to secondary treated effluent (100% - approximately 5mgPL−1 and 8mgNL−1), half strength (50%), P enriched (+P) and N enriched (+N) secondary treated effluents were monitored in a 2 year pot trial. A growth index was derived from measurements of height, girth diameter, branch number and new leaf number. Highest rates of growth were achieved in the +N and 100% treatments, and lowest rates in the +P and 50% treatments. Seasonal growth trends were evident. Continuously waterlogged trees had slightly higher growth rates than those subjected to aeration cycles, demonstrating their suitability to wetland environments. An aerated network through the bark extending to the roots may provide a mechanism of root aeration. Biomass and nutrient partitioning were measured in an experimental constructed Melaleuca wetlands receiving pure effluent. Biomass nutrient accumulation rates were comparable to studies of other macrophytes. M. alternifolia stored approximately three times more N and P than M. quinquenervia. However, M. quinquenervia had higher rates of litter fall induced by severe insect damage, increasing the rate of transfer of nutrients to the long term sediment sink. P concentrations in the senescent leaves were highly responsive to external concentrations, and may be used as an indicator of P loading rates in constructed wetlands. Since senescent leaves provide a major pathway of biomass nutrients into the sediment sink, this provides a self regulating P storage mechanism.

The aim of this study was to assess the expressed preferences of general practitioners (GPs) for alternative organisational models to for-profit GP corporatisation. A review of the findings of six feasibility studies that examined alternative organisational models for general practice in Australia was undertaken. Five feasibility studies were conducted within nine Divisions of General Practice, and a feasibility study was conducted by a state-based organisation among all 15 of its member Divisions. Overall, the six projects demonstrated a strong resistance among most GPs to any alternative model that involved giving up autonomy over practice matters. Consequently, the most favoured alternative organisational model was the "service company" - the establishment of a third party to provide a range of practice support services. In general, there was implicit acceptance that the service company could recover the cost of support service provision by charging GPs on a fee-for-service basis, and also that the Division itself would be the most acceptable organisation to take on this role. However, in four Divisional areas GPs revealed very low motivation towards either working together or with the local Division as a service company. Although these feasibility studies were carried out using different methods, and in a small sample of mostly urban Divisions, they suggest that many GPs would support their Divisions - or some other Division-related third party - to become more active providers of a range of practice support services.

The world is facing a water crisis, and Australia is no exception. New regimes for the supply, use, and delivery of water are needed to ensure a sustainable water future. Black water reuse through ‘sewer mining’ or onsite treatment, proposes to be one initiative that may possibly offer a viable and sustainable alternative approach to water provision in many contexts. However, despite the potential benefits of black water reuse, its feasibility is not yet fully understood. In particular, there is much uncertainty surrounding the following issues: (1) community acceptance, (2) policy complexities, (3) performance impacts of these localised systems, and (4) environmental balance over the full life cycle. This paper outlines research needs surrounding black water reuse with a focus on these four major issues. The paper presents a research agenda to address these important issues. This research agenda involves two Australian commercial case studies: the Council House 2 building in Melbourne, and the Bendigo Bank building in Bendigo.

Effective school-based alcohol prevention programs do exist. However, the overall efficacy of these programs has been compromised by implementation failure and a focus on abstinence based outcomes. The current thesis attempted to overcome such concerns by developing a computer-delivered school-based alcohol prevention program founded on a harm-minimisation approach. The aims of this thesis were to assess whether (1) this program would be both a feasible and acceptable means of overcoming the obstacles encountered in the implementation of school-based drug prevention programs, and (2) it was effective in decreasing alcohol misuse and related harm. CLIMATE Schools: Alcohol Module was developed in collaboration with teachers, students and relevant health and legal professionals. The final curriculum based program consists of six lessons, each with two components. The first component involves students completing an interactive computer-based program, with the second consisting of a variety of individual, small group and class-based activities. The feasibility and efficacy of CLIMATE Schools: Alcohol Module was assessed utilising a cluster randomised controlled trial involving 1434, Year 8 students (13 years old) from sixteen schools. CLIMATE Schools: Alcohol Module was found to be both feasible and acceptable in the school setting. The provision of alcohol prevention information in the background of a computerised teenage drama provided young people with an education program they enjoyed in a context to which they could relate. Teachers reported a willingness to implement CLIMATE Schools: Alcohol Module in routine practice. They believed it to be a high quality program which was superior to other drug education programs. CLIMATE Schools: Alcohol Module led to significant increases in knowledge of harm minimisation skills and subdued alcohol related expectancies. It was effective in reducing alcohol use, misuse and related harms for females, but not for males. The differential effects of gender are extensively discussed and implications for future research considered. CLIMATE Schools: Alcohol Module was clearly both feasible and acceptable and has the potential to offer an innovative new platform for the delivery of prevention programs in schools.

Entrepreneurship education was introduced in South African schools in 2000 when it was made part of the Economics and Management Science curriculum for Grades 3 to 9, followed by incorporation in the Business Studies curriculum for grades 10 to 12. Problems noted by Shay and Nchu (2015) were that not all schools offered entrepreneurship education. Little is known about post-program effectiveness in actual start-ups and business performance. A study by Peterman and Kennedy (2013) investigating the effects of Young Achievement Australia on a sample of high school students in Australia found that the desirability and feasibility of entrepreneurship after attending the programme had increased, indicating that entrepre

Carbon dioxide (CO2) storage is a vital part of the energy transition to low emissions. The Jurassic age Precipice Sandstone of the Surat Basin in Queensland, Australia, has been investigated as a suitable reservoir for CO2 storage. The overlying Evergreen Formation is a thick, interbedded mudstone and sandstone seal, and regarded a regional aquitard. Wells have been drilled for feasibility studies, initially in CTSCo’s Glenhaven region, near Wandoan, and recently in the southern Surat Basin near the town of Moonie. Since the Precipice Sandstone is also a Great Artesian Basin aquifer, the southern region with deeper groundwater unsuitable for stock use, and minimal to stagnant flow, is likely a more suitable site. The University of Queensland has undertaken research in both potential storage regions, and more broadly across the basin, including the separate Moonie oil field. This presentation will focus on core characterisation, experimental and modelled geochemical CO2-water-rock reactions and their impacts on water quality, porosity and permeability, and the effects of gas stream impurities SOx, NOx and O2. In addition, it may touch on field studies to assess existing hydrochemistry, water quality and native greenhouse gases in the Precipice Sandstone, and in the Hutton Sandstone that overlies the Evergreen Formation.

Abstract There is a significant drive to decarbonise the energy system resulting in a need to integrate large quantities of intermittent renewable power into both onshore consumer grids and offshore isolated grids. This brings significant technical challenges that can be addressed using the right energy storage technology for future times of intermittency and peak power demands. The innovative Repurposed Offshore Pipelines as Energy Storage (ROPES) solution repurposes existing, aged offshore installations into energy storage systems based on proven hydro-pneumatic principles, towards a cost-competitive, highly reliable system. Findings from a recent Concept Assess study prove the cost competitiveness of the solution, thanks to alow Levelised Cost of Storage (LCOS), paired with the value of deferring full decommissioning of existing assets. The study scope covers aspects of market recognition, technical feasibility, risk and opportunity assessment, cost estimates and value delivery to potential clients. Four case studies covering potential prospects offshore Australia and in the North Sea illustrate the diverse architectural application of the solution. The resultant cost estimates form the NPV analysis, and eventually derive the solution LCOS, which shows cost superiority over marinised Li-ion batteries and is comparable to onshore battery systems. The solution shows clear benefits over a typical battery storage system, including reduced safety risks, less topside constraints along with a longer and predictable operating lifetime. The ROPES solution enables the storage of renewable power whilst allowing to optimise time and expenditure for decommissioning of existing infrastructure, therefore represents a unique opportunity to unlock a new market segment within the offshore energy sector.

American Samoa is an unincorporated territory of the U.S. roughly 2,300 air miles southwest of Honolulu and about 2,700 miles north of Australia. The largest and most populated island in American Samoa is Tutuila, which is located the territory’s historic capitol of Pago Pago. The territory is home to the world’s largest tuna cannery. Population growth has been dramatic and the island’s energy costs have increased substantially in recent years. The American Samoa Power Authority (ASPA) is responsible for solid waste collection and disposal in the territory with landfilling being the primary mode of waste disposal. However, limited available land on the main island due to volcanic topography limits the long-term use of landfilling as the island’s sole waste management tool. The relative isolated location of American Samoa and the instability of world oil markets have prompted ASPA to look at more environmentally and economically sustainable means of solid waste management. As an outgrowth of its research, ASPA submitted and received a technical assistance grant from the U.s. Department of the Interior to conduct an extensive waste composition study and EfW feasibility study to examine the advantages and disadvantages of efW for American Samoa. The results of these studies have been completed by SCS on behalf of ASPA, which is currently taking steps to permit and procure a 2.0 megawatt, modular efW facility that will go online in 2012 as part of a public private partnership. The lessons learned by SCs and ASPA during the course of the investigations are illustrative of the types of long-term, waste management and energy decision-making that many small communities will have to undertake to attain viable and sustainable alternatives.

Gas production flowlines are presenting flow assurance challenges in hydrate management resulting from low ambient seawater temperatures in an increasing number of deepwater developments. During operation the equilibrium hydrate temperature of the produced fluid may be above the minimum seabed temperature, and hence there is a risk of hydrate blockage in the subsea system should the hydrate inhibition system fail. The continuous injection of MEG, with little or no insulation of the subsea system, is a common hydrate mitigation strategy for a gas production system. If insufficient inhibitor is injected there is a risk of hydrates forming and potential blockage of the pipeline in parts of the field. The industry-preferred approach for hydrate blockage remediation is Dual Sided Depressurisation (DSD). The objective is to depressurise the flowline to below hydrate onset conditions, allowing hydrate dissociation and safely disposing of the gas inventory. This is typically performed by one of two methods; installation of a dual flowline system for facility based depressurisation (with CAPEX implications); or a Mobile Offshore Drilling Unit (MODU) can be connected to an appropriate point upstream of the blockage to allow simultaneous depressurisation at the MODU and the facility (with OPEX implications). It is recognised that either method incurs significant costs. Typically the cost and time uncertainties of bringing in a MODU to solve these production stoppages is unattractive. Consequently subsea gas developments have often incurred the increased CAPEX of providing dual flowlines to permit DSD from the facility. An optimisation of the MODU-based intervention method is the subject of this paper. The feasibility of using a “lightweight” intervention vessel (for example an Offshore Support Vessel) in place of the MODU to depressurise the flowline is discussed. This paper discusses hydrate remediation difficulties and case studies; presents emerging hydrate remediation methods and briefly introduces vessel requirements. In discussing this optimisation, this paper also presents an introduction to hydrate remediation theory, some practical challenges, case studies and vessel requirements. The study concluded: • Significant CAPEX reductions may be achieved by adopting the outlined strategy; namely avoiding dual flowline infrastructure, and ensuring a reduced response time and day rate for any hydrate remediation operations to be performed. • For this strategy to be adopted cost effectively, pre-engineering, along with suitable contractual arrangements, are required to make the necessary equipment and personnel resources readily available should a hydrate blockage occur. For assets in remote locations, e.g. Australia, making the resources available is a significant challenge. • Flowline system access for depressurisation may be achieved by two methods; via the subsea Christmas tree or via suitably located fluid injection/vent access point(s).

The increasing movement of people and products caused by modern economic dynamics has burdened transportation systems. Both industrialized and developing countries have faced transportation problems in urbanized regions and in their major intercity corridors. Regional and highway congestion have become a chronic problem, causing longer travel times, economic inefficiencies, deterioration of the environment and quality of life. Congestion problems are also occurring at airports and air corridors, with similar negative effects. In the medium distance travel market (from 160 up to 800 km), too far to drive and too short to fly, High Speed Rail (HSR) technology has emerged as a modern transportation system, as it is the most efficient means for transporting large passenger volumes with high speed, reliability, safety, passenger comfort and environmental performance. HSR system’s feasibility will depend on its capacity to generate social benefits (i.e. increased mobility rates, reduced congestion, capacity increase and reduced environmental costs), to be balanced with the high construction, maintenance and operational costs. So, it is essential to select HSR corridors with strong passenger demands to maximize these benefits. The first HSR line was Japan’s Shinkansen service, a dedicated HSR system, between Tokyo and Osaka, launched in 1964, which is currently the most heavily loaded HSR corridor in the world. France took the next step, launching the Train à Grande Vitesse (TGV), in 1981, with a dedicated line with shared-use segments in urban areas, running between Paris and Lyon. Germany joined the venture in the early 1990 with the Inter City Express – ICE, with a coordinated program of improvements in existent rail infrastructure and Spain, in 1992, with the Alta Velocidad Espanola – AVE, with dedicated greenfield lines. Since then, these systems have continuously expanded their network. Currently, many countries are evaluating the construction of new HSR lines, with European Commission deeming the expansion of the Trans European Network as a priority. United Kingdom, for example, has just awarded construction contracts for building the so called HS2, an HSRexpanded line linking London to the northern territory. China, with its dynamic economic development, has launched its HSR network in 2007 and has sped up working on its expansion, and currently holds the highest HSR network. United States, which currently operates high speed trainsets into an operationally restricted corridor (the so called Northeast Corridor (NEC), linking Washington, New York and Boston), has also embarked into the high speed rail world with the launch of Californian HSR Project, currently under construction, aimed to link Los Angeles to San Francisco mega regions, the ongoing studies for Texas HSR project, to connect Dallas to Houston, into a wholly privately funding model, as well as studies for a medium to long term NEC upgrade for HSR. Australia and Brazil are also seeking to design and launch their first HSR service, into a time consuming process, in which a deep discussion about social feasibility and affordability is under way. This work is supposed to present an overview of HSR technology worldwide, with an assessment of the main technical, operational and economical features of Asian and European HSR systems, followed by a snapshot of the general guidelines applied to some planned HSR projects, highlighting their demand attraction potential, estimated costs, as well as their projected economic and environmental benefits.

Abstract There is a significant drive to decarbonise the energy system resulting in a need to integrate large quantities of intermittent renewable power into both onshore consumer grids and offshore isolated grids. This brings significant technical challenges that can be addressed using the right energy storage technology for future times of intermittency and peak power demands. The PowerBundle is a full-scale subsea hydro-pneumatic energy storage (HPES) system. Electricity is used to pump seawater into a closed pipeline bundle to compress a volume of pre-charged air and is then recovered by allowing the compressed air to push the water back out through a hydraulic turbine generator. The surrounding seawater acts as a natural heatsink, avoiding thermal losses and making the solution highly energy efficient. At the heart of the development is an established supply-chain, developed over 40 years, which will deliver a reliable system with an up to 40-year service lifetime, independent of the charging-discharging regime. The system avoids any harmful chemicals and embodies the core principles of safety, reliability, sustainability and cost-effectiveness. This HPES solution will be attractive for offshore projects requiring an interface to provide power balancing and scheduling, which will benefit stakeholders in the oil-and-gas and renewable energy sectors seeking to deliver intermittent power to their end customer. This development will lead to a significant reduction of greenhouse gas (GHG) emissions due to more holistic renewable infrastructure. The PowerBundle provides a scalable storage solution which can be placed in waters close to land, supporting the scale-up, resilience and economies of renewable electricity. However, as a first step, the innovative Repurposed Offshore Pipelines as Energy Storage (ROPES) solution repurposes existing, aged offshore installations into energy storage systems based on proven hydro-pneumatic principles, towards a cost-competitive, highly reliable system. Findings from a recent Concept Assess study prove the cost competitiveness of the solution, thanks to a low Levelised Cost of Storage (LCOS), paired with the value of deferring full decommissioning of existing assets. The study scope covers aspects of market recognition, technical feasibility, risk and opportunity assessment, cost estimates and value delivery to potential clients. Four case studies covering potential prospects offshore Australia and in the North Sea illustrate the diverse architectural application of the solution. The resultant cost estimates form the Net Present Value (NPV) analysis, and eventually derive the solution LCOS, which shows cost superiority over marinised Li-ion batteries and is comparable to onshore battery systems. The solution shows clear benefits over a typical battery storage system, including reduced safety risks, less topside constraints along with a longer and predictable operating lifetime. The ROPES solution enables the storage of renewable power whilst allowing to optimise time and expenditure for decommissioning of existing infrastructure, therefore represents a unique opportunity to unlock a new market segment within the offshore energy sector while the PowerBundle technology reaches maturity.

In the last 5 years in Canada, regulators have been requesting that new pipeline projects provide quantitative risk management of all credible geohazards involving the proposed pipeline corridor so it can be demonstrated that geohazards are being recognized prioritized and that adequate resources are being allocated and to minimize the impact of adverse consequences of pipeline construction and operation. Complete risk management includes risk analysis that identifies credible geohazards sites, estimates their annual frequency or probability of pipeline failure and, when combined with a consequence of pipeline failure, estimates the risk from each hazard. This paper presents a framework and methodology that quantitatively estimates the Frequency of Loss of Containment (FLoC) for several types of geohazards that meet the requirements for geohazard identification and frequency analysis components of risk analysis. This framework builds on an international geohazard management framework advanced in the last decade by the Australian Geomechanics Society, British Columbia forestry industry, used in geohazard management programs for operating pipelines and proposed pipeline projects in Canada. The framework provides a repeatable and defensible methodology that is intended to be scalable to accept inputs from feasibility level desktop studies, through field-based observations, and incorporate proposed mitigations. This updated framework was most recently implemented on a proposed large diameter transmission pipeline route crossing the varied terrains of Western Canada, the results of which have been adjusted for Owner confidentiality, but are presented to demonstrate the application of the methodology and the effectiveness of communicating the overall hazard frequency reduction as a result of applying site specific mitigations.

Overview Skin cancer prevention is a component of the new Cancer Plan 2022–27, which guides the work of the Cancer Institute NSW. To lessen the impact of skin cancer on the community, the Cancer Institute NSW works closely with the NSW Skin Cancer Prevention Advisory Committee, comprising governmental and non-governmental organisation representatives, to develop and implement the NSW Skin Cancer Prevention Strategy. Primary Health Networks and primary care providers are seen as important stakeholders in this work. To guide improvements in skin cancer prevention and inform the development of the next NSW Skin Cancer Prevention Strategy, an up-to-date review of the evidence on the effectiveness and feasibility of skin cancer prevention activities in primary care is required. A research team led by the Daffodil Centre, a joint venture between the University of Sydney and Cancer Council NSW, was contracted to undertake an Evidence Check review to address the questions below. Evidence Check questions This Evidence Check aimed to address the following questions: Question 1: What skin cancer primary prevention activities can be effectively administered in primary care settings? As part of this, identify the key components of such messages, strategies, programs or initiatives that have been effectively implemented and their feasibility in the NSW/Australian context. Question 2: What are the main barriers and enablers for primary care providers in delivering skin cancer primary prevention activities within their setting? Summary of methods The research team conducted a detailed analysis of the published and grey literature, based on a comprehensive search. We developed the search strategy in consultation with a medical librarian at the University of Sydney and the Cancer Institute NSW team, and implemented it across the databases Embase, MEDLINE, PsycInfo, Scopus, Cochrane Central and CINAHL. Results were exported and uploaded to Covidence for screening and further selection. The search strategy was designed according to the SPIDER tool for Qualitative and Mixed-Methods Evidence Synthesis, which is a systematic strategy for searching qualitative and mixed-methods research studies. The SPIDER tool facilitates rigour in research by defining key elements of non-quantitative research questions. We included peer-reviewed and grey literature that included skin cancer primary prevention strategies/ interventions/ techniques/ programs within primary care settings, e.g. involving general practitioners and primary care nurses. The literature was limited to publications since 2014, and for studies or programs conducted in Australia, the UK, New Zealand, Canada, Ireland, Western Europe and Scandinavia. We also included relevant systematic reviews and evidence syntheses based on a range of international evidence where also relevant to the Australian context. To address Question 1, about the effectiveness of skin cancer prevention activities in primary care settings, we summarised findings from the Evidence Check according to different skin cancer prevention activities. To address Question 2, about the barriers and enablers of skin cancer prevention activities in primary care settings, we summarised findings according to the Consolidated Framework for Implementation Research (CFIR). The CFIR is a framework for identifying important implementation considerations for novel interventions in healthcare settings and provides a practical guide for systematically assessing potential barriers and facilitators in preparation for implementing a new activity or program. We assessed study quality using the National Health and Medical Research Council (NHMRC) levels of evidence. Key findings We identified 25 peer-reviewed journal articles that met the eligibility criteria and we included these in the Evidence Check. Eight of the studies were conducted in Australia, six in the UK, and the others elsewhere (mainly other European countries). In addition, the grey literature search identified four relevant guidelines, 12 education/training resources, two Cancer Care pathways, two position statements, three reports and five other resources that we included in the Evidence Check. Question 1 (related to effectiveness) We categorised the studies into different types of skin cancer prevention activities: behavioural counselling (n=3); risk assessment and delivering risk-tailored information (n=10); new technologies for early detection and accompanying prevention advice (n=4); and education and training programs for general practitioners (GPs) and primary care nurses regarding skin cancer prevention (n=3). There was good evidence that behavioural counselling interventions can result in a small improvement in sun protection behaviours among adults with fair skin types (defined as ivory or pale skin, light hair and eye colour, freckles, or those who sunburn easily), which would include the majority of Australians. It was found that clinicians play an important role in counselling patients about sun-protective behaviours, and recommended tailoring messages to the age and demographics of target groups (e.g. high-risk groups) to have maximal influence on behaviours. Several web-based melanoma risk prediction tools are now available in Australia, mainly designed for health professionals to identify patients’ risk of a new or subsequent primary melanoma and guide discussions with patients about primary prevention and early detection. Intervention studies have demonstrated that use of these melanoma risk prediction tools is feasible and acceptable to participants in primary care settings, and there is some evidence, including from Australian studies, that using these risk prediction tools to tailor primary prevention and early detection messages can improve sun-related behaviours. Some studies examined novel technologies, such as apps, to support early detection through skin examinations, including a very limited focus on the provision of preventive advice. These novel technologies are still largely in the research domain rather than recommended for routine use but provide a potential future opportunity to incorporate more primary prevention tailored advice. There are a number of online short courses available for primary healthcare professionals specifically focusing on skin cancer prevention. Most education and training programs for GPs and primary care nurses in the field of skin cancer focus on treatment and early detection, though some programs have specifically incorporated primary prevention education and training. A notable example is the Dermoscopy for Victorian General Practice Program, in which 93% of participating GPs reported that they had increased preventive information provided to high-risk patients and during skin examinations. Question 2 (related to barriers and enablers) Key enablers of performing skin cancer prevention activities in primary care settings included: • Easy access and availability of guidelines and point-of-care tools and resources • A fit with existing workflows and systems, so there is minimal disruption to flow of care • Easy-to-understand patient information • Using the waiting room for collection of risk assessment information on an electronic device such as an iPad/tablet where possible • Pairing with early detection activities • Sharing of successful programs across jurisdictions. Key barriers to performing skin cancer prevention activities in primary care settings included: • Unclear requirements and lack of confidence (self-efficacy) about prevention counselling • Limited availability of GP services especially in regional and remote areas • Competing demands, low priority, lack of time • Lack of incentives.

Background Lung cancer is the number one cause of cancer death worldwide.(1) It is the fifth most commonly diagnosed cancer in Australia (12,741 cases diagnosed in 2018) and the leading cause of cancer death.(2) The number of years of potential life lost to lung cancer in Australia is estimated to be 58,450, similar to that of colorectal and breast cancer combined.(3) While tobacco control strategies are most effective for disease prevention in the general population, early detection via low dose computed tomography (LDCT) screening in high-risk populations is a viable option for detecting asymptomatic disease in current (13%) and former (24%) Australian smokers.(4) The purpose of this Evidence Check review is to identify and analyse existing and emerging evidence for LDCT lung cancer screening in high-risk individuals to guide future program and policy planning. Evidence Check questions This review aimed to address the following questions: 1. What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? 2. What is the evidence of potential harms from lung cancer screening for higher-risk individuals? 3. What are the main components of recent major lung cancer screening programs or trials? 4. What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Summary of methods The authors searched the peer-reviewed literature across three databases (MEDLINE, PsycINFO and Embase) for existing systematic reviews and original studies published between 1 January 2009 and 8 August 2019. Fifteen systematic reviews (of which 8 were contemporary) and 64 original publications met the inclusion criteria set across the four questions. Key findings Question 1: What is the evidence for the effectiveness of lung cancer screening for higher-risk individuals? There is sufficient evidence from systematic reviews and meta-analyses of combined (pooled) data from screening trials (of high-risk individuals) to indicate that LDCT examination is clinically effective in reducing lung cancer mortality. In 2011, the landmark National Lung Cancer Screening Trial (NLST, a large-scale randomised controlled trial [RCT] conducted in the US) reported a 20% (95% CI 6.8% – 26.7%; P=0.004) relative reduction in mortality among long-term heavy smokers over three rounds of annual screening. High-risk eligibility criteria was defined as people aged 55–74 years with a smoking history of ≥30 pack-years (years in which a smoker has consumed 20-plus cigarettes each day) and, for former smokers, ≥30 pack-years and have quit within the past 15 years.(5) All-cause mortality was reduced by 6.7% (95% CI, 1.2% – 13.6%; P=0.02). Initial data from the second landmark RCT, the NEderlands-Leuvens Longkanker Screenings ONderzoek (known as the NELSON trial), have found an even greater reduction of 26% (95% CI, 9% – 41%) in lung cancer mortality, with full trial results yet to be published.(6, 7) Pooled analyses, including several smaller-scale European LDCT screening trials insufficiently powered in their own right, collectively demonstrate a statistically significant reduction in lung cancer mortality (RR 0.82, 95% CI 0.73–0.91).(8) Despite the reduction in all-cause mortality found in the NLST, pooled analyses of seven trials found no statistically significant difference in all-cause mortality (RR 0.95, 95% CI 0.90–1.00).(8) However, cancer-specific mortality is currently the most relevant outcome in cancer screening trials. These seven trials demonstrated a significantly greater proportion of early stage cancers in LDCT groups compared with controls (RR 2.08, 95% CI 1.43–3.03). Thus, when considering results across mortality outcomes and early stage cancers diagnosed, LDCT screening is considered to be clinically effective. Question 2: What is the evidence of potential harms from lung cancer screening for higher-risk individuals? The harms of LDCT lung cancer screening include false positive tests and the consequences of unnecessary invasive follow-up procedures for conditions that are eventually diagnosed as benign. While LDCT screening leads to an increased frequency of invasive procedures, it does not result in greater mortality soon after an invasive procedure (in trial settings when compared with the control arm).(8) Overdiagnosis, exposure to radiation, psychological distress and an impact on quality of life are other known harms. Systematic review evidence indicates the benefits of LDCT screening are likely to outweigh the harms. The potential harms are likely to be reduced as refinements are made to LDCT screening protocols through: i) the application of risk predication models (e.g. the PLCOm2012), which enable a more accurate selection of the high-risk population through the use of specific criteria (beyond age and smoking history); ii) the use of nodule management algorithms (e.g. Lung-RADS, PanCan), which assist in the diagnostic evaluation of screen-detected nodules and cancers (e.g. more precise volumetric assessment of nodules); and, iii) more judicious selection of patients for invasive procedures. Recent evidence suggests a positive LDCT result may transiently increase psychological distress but does not have long-term adverse effects on psychological distress or health-related quality of life (HRQoL). With regards to smoking cessation, there is no evidence to suggest screening participation invokes a false sense of assurance in smokers, nor a reduction in motivation to quit. The NELSON and Danish trials found no difference in smoking cessation rates between LDCT screening and control groups. Higher net cessation rates, compared with general population, suggest those who participate in screening trials may already be motivated to quit. Question 3: What are the main components of recent major lung cancer screening programs or trials? There are no systematic reviews that capture the main components of recent major lung cancer screening trials and programs. We extracted evidence from original studies and clinical guidance documents and organised this into key groups to form a concise set of components for potential implementation of a national lung cancer screening program in Australia: 1. Identifying the high-risk population: recruitment, eligibility, selection and referral 2. Educating the public, people at high risk and healthcare providers; this includes creating awareness of lung cancer, the benefits and harms of LDCT screening, and shared decision-making 3. Components necessary for health services to deliver a screening program: a. Planning phase: e.g. human resources to coordinate the program, electronic data systems that integrate medical records information and link to an established national registry b. Implementation phase: e.g. human and technological resources required to conduct LDCT examinations, interpretation of reports and communication of results to participants c. Monitoring and evaluation phase: e.g. monitoring outcomes across patients, radiological reporting, compliance with established standards and a quality assurance program 4. Data reporting and research, e.g. audit and feedback to multidisciplinary teams, reporting outcomes to enhance international research into LDCT screening 5. Incorporation of smoking cessation interventions, e.g. specific programs designed for LDCT screening or referral to existing community or hospital-based services that deliver cessation interventions. Most original studies are single-institution evaluations that contain descriptive data about the processes required to establish and implement a high-risk population-based screening program. Across all studies there is a consistent message as to the challenges and complexities of establishing LDCT screening programs to attract people at high risk who will receive the greatest benefits from participation. With regards to smoking cessation, evidence from one systematic review indicates the optimal strategy for incorporating smoking cessation interventions into a LDCT screening program is unclear. There is widespread agreement that LDCT screening attendance presents a ‘teachable moment’ for cessation advice, especially among those people who receive a positive scan result. Smoking cessation is an area of significant research investment; for instance, eight US-based clinical trials are now underway that aim to address how best to design and deliver cessation programs within large-scale LDCT screening programs.(9) Question 4: What is the cost-effectiveness of lung cancer screening programs (include studies of cost–utility)? Assessing the value or cost-effectiveness of LDCT screening involves a complex interplay of factors including data on effectiveness and costs, and institutional context. A key input is data about the effectiveness of potential and current screening programs with respect to case detection, and the likely outcomes of treating those cases sooner (in the presence of LDCT screening) as opposed to later (in the absence of LDCT screening). Evidence about the cost-effectiveness of LDCT screening programs has been summarised in two systematic reviews. We identified a further 13 studies—five modelling studies, one discrete choice experiment and seven articles—that used a variety of methods to assess cost-effectiveness. Three modelling studies indicated LDCT screening was cost-effective in the settings of the US and Europe. Two studies—one from Australia and one from New Zealand—reported LDCT screening would not be cost-effective using NLST-like protocols. We anticipate that, following the full publication of the NELSON trial, cost-effectiveness studies will likely be updated with new data that reduce uncertainty about factors that influence modelling outcomes, including the findings of indeterminate nodules. Gaps in the evidence There is a large and accessible body of evidence as to the effectiveness (Q1) and harms (Q2) of LDCT screening for lung cancer. Nevertheless, there are significant gaps in the evidence about the program components that are required to implement an effective LDCT screening program (Q3). Questions about LDCT screening acceptability and feasibility were not explicitly included in the scope. However, as the evidence is based primarily on US programs and UK pilot studies, the relevance to the local setting requires careful consideration. The Queensland Lung Cancer Screening Study provides feasibility data about clinical aspects of LDCT screening but little about program design. The International Lung Screening Trial is still in the recruitment phase and findings are not yet available for inclusion in this Evidence Check. The Australian Population Based Screening Framework was developed to “inform decision-makers on the key issues to be considered when assessing potential screening programs in Australia”.(10) As the Framework is specific to population-based, rather than high-risk, screening programs, there is a lack of clarity about transferability of criteria. However, the Framework criteria do stipulate that a screening program must be acceptable to “important subgroups such as target participants who are from culturally and linguistically diverse backgrounds, Aboriginal and Torres Strait Islander people, people from disadvantaged groups and people with a disability”.(10) An extensive search of the literature highlighted that there is very little information about the acceptability of LDCT screening to these population groups in Australia. Yet they are part of the high-risk population.(10) There are also considerable gaps in the evidence about the cost-effectiveness of LDCT screening in different settings, including Australia. The evidence base in this area is rapidly evolving and is likely to include new data from the NELSON trial and incorporate data about the costs of targeted- and immuno-therapies as these treatments become more widely available in Australia.

Phytophagous insects respond to chemicals from their host plants in a number of ways, including orientation or attraction in response to volatiles produced by plants. Orientation to odors from host plants may occur in order to locate food, mates, or oviposition sites. A detailed understanding of these behaviors are the chemical stimuli evoking them may provide useful means for attracting and trapping insect pests of crop plants. Heliothine moths (Helicoverpa and Heliothis herein) include a number of major pests of cultivated crop plants throughout the world. In North America, these include Heliothis virescens and Helicoverpa zea. In much of Eurasia (including Israel) Australia, and Africa, these include Helicoverpa armigera and Helicoverpa peltigera. These 4 species of concern all are attracted to odorants from host plants (Tingle and Mitchell 2992, Mitchell et al 1991, 1992 BARD feasibility study report). Host plant chemicals also play a role in the sexual behavior of Helicoverpa species. Synthesis and possibly release of sex pheromone in H. zea and H. phloxiphaga is stimulated by kairomones from hosts plants (Raina 1988, 1992). Pheromona scent marking on host plants also occurs in H. virescens and H. zea. Studies of several other insects, including the cabbage looper Trichoplusia ni, have a variety of other behaviors may occur in association with host plants, including the use of plants as sexual rendesvous sites and of direct involvement of plant chemicals in sexual behavior. Some pest species of moths also may use host plants as adult food sources. These studies were undertaken to develop a more thorough understanding of how Heliothis/Helicoverpa moths use host plant odorants to locate and select foods, mates, and oviposition sites. We used Heliothis virescens and Helicoverpa zea in Florida, and Helicoverpa armigera and Helicoverpa peltigera in Israel as objects of study because of their pest status. It is hoped that such an understanding will provide direction for work to discover and develop novel means to control these pests through behavioral manipulation. The specific objectives of the proposal were to 1) identify host odor affects on known Heliothine sexual behavior, 2) identify novel sexual behavior that is how dependent, 3) isolate and characterize host kairomones important to pest Heliothine host and mate-location behavior, and 4) investigate female attraction to males.