Добірка наукової літератури з теми "Facile Michael Addition Reaction"
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Статті в журналах з теми "Facile Michael Addition Reaction"
Reddy, S. Madhava, and H. M. Walborsky. "A facile intramolecular Michael addition reaction." Journal of Organic Chemistry 51, no. 13 (June 1986): 2605–7. http://dx.doi.org/10.1021/jo00363a042.
Повний текст джерелаStepanova, Ekaterina, Andrey Maslivets, Svetlana Kasatkina, and Maksim Dmitriev. "Diversity-Oriented Synthesis via Catalyst-Free Addition of Ketones to [e]-Fused 1H-Pyrrole-2,3-diones." Synthesis 50, no. 24 (August 20, 2018): 4897–904. http://dx.doi.org/10.1055/s-0037-1610647.
Повний текст джерелаWang, Yi-Fan, Cheng-Yu He, Longlei Hou, Ping Tian, Guo-Qiang Lin та Xiaofeng Tong. "Facile Access to 1,5-Benzodiazepines via Amine-Promoted (4+3) Annulations of δ-Acetoxy Allenoates with o-Diaminobenzenes under Mild Conditions". Synlett 29, № 09 (23 березня 2018): 1176–80. http://dx.doi.org/10.1055/s-0037-1609347.
Повний текст джерелаYang, Jingya, Tianyuan Li, Hongyan Zhou, Nana Li, Dongtai Xie, and Zheng Li. "Potassium Hydroxide Catalysed Intermolecular Aza-Michael Addition of 3-Cyanoindole to Aromatic Enones." Synlett 28, no. 10 (February 28, 2017): 1227–31. http://dx.doi.org/10.1055/s-0036-1588152.
Повний текст джерелаTerent'ev, Alexander O., Vera A. Vil', Ivan A. Yaremenko, Oleg V. Bityukov, Dmitri O. Levitsky, Vladimir V. Chernyshev, Gennady I. Nikishin та Fabrice Fleury. "Preparation of a microsized cerium chloride-based catalyst and its application in the Michael addition of β-diketones to vinyl ketones". New J. Chem. 38, № 4 (2014): 1493–502. http://dx.doi.org/10.1039/c3nj01454a.
Повний текст джерелаBoruah, Romesh C., Anil Saikia, Apurba Chetia, and Utpal Bora. "A Facile Synthesis of 1,6-Diketonesvia a Three-Component Michael Addition Reaction." Synlett, no. 10 (2003): 1506–8. http://dx.doi.org/10.1055/s-2003-40821.
Повний текст джерелаRulev, Alexander Yu, Alexey R. Romanov, Alexander V. Popov, Evgeniy V. Kondrashov, and Sergey V. Zinchenko. "Reaction of Bromoenones with Amidines: A Simple Catalyst-Free Approach to Trifluoromethylated Pyrimidines." Synthesis 52, no. 10 (March 9, 2020): 1512–22. http://dx.doi.org/10.1055/s-0040-1707969.
Повний текст джерелаLin, Ning, Qiu-Xiang Wei, Li-Hua Jiang, Yan-Qiu Deng, Zhen-Wei Zhang, and Qing Chen. "Asymmetric Michael Addition of Malononitrile with Chalcones via Rosin-Derived Bifunctional Squaramide." Catalysts 10, no. 1 (December 20, 2019): 14. http://dx.doi.org/10.3390/catal10010014.
Повний текст джерелаGuy Taylor, Jason, Wellington Martins Ventura, and Luiz Guilherme Souza de Assis. "Facile Synthesis of Indolines by a Tandem Nitro-reduction Aza Michael Addition Reaction." HETEROCYCLES 87, no. 10 (2013): 2023. http://dx.doi.org/10.3987/com-13-12789.
Повний текст джерелаFustero, Santos, Javier Moscardó, María Sánchez-Roselló, Elsa Rodríguez, and Pablo Barrio. "Tandem Nucleophilic Addition−Intramolecular Aza-Michael Reaction: Facile Synthesis of Chiral Fluorinated Isoindolines." Organic Letters 12, no. 23 (December 3, 2010): 5494–97. http://dx.doi.org/10.1021/ol102341n.
Повний текст джерелаДисертації з теми "Facile Michael Addition Reaction"
Budhavaram, Naresh Kumar. "Facile protein and amino acid substitution reactions and their characterization using thermal, mechanical and optical techniques." Diss., Virginia Tech, 2010. http://hdl.handle.net/10919/40340.
Повний текст джерелаPh. D.
Jha, Sushil C. "Catalytic, enantioselective michael addition reaction." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2002. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2496.
Повний текст джерелаLombardi, Federico. "Computational study on the asymmetric aminocatalysed Michael addition reaction of cyclohexanone to trans–β–nitrostyrene". Master's thesis, Alma Mater Studiorum - Università di Bologna, 2021. http://amslaurea.unibo.it/23186/.
Повний текст джерелаZhu, Sunsheng. "Novel Approach to Polyhedral Oligmeric Silsesquioxane-Based Giant Surfactants Basd on Thiol-Michael Addition "Click" Reaction." University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1399555570.
Повний текст джерелаLi, Mao. "Iron(III) catalyzed asymmetric Diels-Alder reaction - Iron(II) catalyzed thia-Michael addition and aldehyde allylation reactions." Doctoral thesis, Université Laval, 2019. http://hdl.handle.net/20.500.11794/34969.
Повний текст джерелаIron catalysts are employed in three different organic transformations owing to their advantages: environmental friendliness, being less expensive and abundant on the Earth. The first project deals with asymmetric Diels-Alder reactions of α, β-unsaturated oxazolidin-2-one derivatives catalyzed by Fe¹¹¹ and a chiral bipyridine ligand. In order to obtain the optimized reaction conditions, we screened different solvents, catalyst loading, various reaction times and a variety of iron salts such as Fe(ClO₄)₂·6H₂O, Fe(ClO₄)₂·6H₂O, Fe(OTf)₃, Fe(OTf)₂, FeCl₂, FeCl₃, FeBr₃ and FeI₃. As a result, the reaction between cyclopentadiene and 3-alkenoyl-1,3-oxazolidin-2-one was carried out at –30 °C in CH₃CN in 1.5 h, with Fe(ClO₄)₃·6H₂O (2 mol%) complexed with the chiral bipyridine ligand (2.4 mol%) as catalyst, providing an excellent yield (99%) and an excellent enantiomeric excess (98%). Decreased enantioselectivities were observed for less-reactive dienes. Overall, less than 10 mol% of catalyst loading was employed. The great advantages of this project are the mild reaction temperature, very low catalyst loading, excellent yields and enantioselectivities and the applicability to a wide scope of substrates. Meanwhile, iron catalysts were used in thia-Michael additions by two different approaches. The first one is about thia-Michael additions catalyzed by Fe(OTf)₂ in EtOH at room temperature. This green method allows the thia-Michael additions to be catalyzed by a green iron salt (5 mol% of Fe(OTf)₂), a green and commonly used solvent EtOH at room temperature under ambient atmosphere. The generality of this reaction was demonstrated by applying it to different Michael acceptors, and to aromatic and aliphatic thiols. The second method is about thia-Michael additions catalyzed by Fe(OTf)₂ in 2-Me-THF, which is in agreement with the green chemistry principles by using a green Fe(OTf)₂ and a green solvent 2-Me-THF at room temperature or 50 °C under air atmosphere. The last project is about asymmetric allylation reactions catalyzed by Fe(OTf)₂ using a chiral ligand. With the study of a variety of chiral ligands, we selected 5 mol% of Fe(OTf)₂ and 6 mol% of Pybox ligand which catalyzed the reaction in good yield (70%) and 32% of ee. The utilization of 20 mol% of TMSCl is essential for the effectiveness of the reaction
LOPS, CARMINE. "Development of organocatalytic and stereoselective reactions." Doctoral thesis, Università degli Studi di Trieste, 2018. http://hdl.handle.net/11368/2918472.
Повний текст джерелаIbrahim, Houssein. "Synthèse de nouveaux composés chiraux à partir d'isosorbide et d'isomannide : applications en catalyse asymétrique." Thesis, Paris 11, 2011. http://www.theses.fr/2011PA112159.
Повний текст джерелаThe Thesis deals with the synthesis of new chiral compounds derived from isosorbide and isomannide and their applications to asymmetric catalysis. The first part of this work consisted in perfecting the chemical and enantioselective hydrogenation conditions of olefins using chiral monophosphines as ligands (up to 96% ee). These phosphines were also used as organocatalysts for [3+2] cyclisation reactions showing good catalytic activity and moderate enantioselectivity. The second part turned to the synthesis of a series of chiral nitrogen compounds which were evaluated in the asymmetric transfer hydrogenation of aromatic ketones giving good enantioselectivity (up to 73% ee). The complexes formed with amine ligands were also applied to the addition reaction of phenylacetylene to imines. Good catalytic activity but low enantioselectivity were observed. These nitrogen compounds were also used as organocatalysts in the Michael addition reaction of aromatic ketones to the nitrostyrene. Again, low enantiomeric excess was obtained. The last part of this work consisted in preparing new chiral thiourea compounds which were applied as organocatalysts to the Friedel-Crafts alkylation reaction of different indoles with nitroolefines, and to the conjugate addition reaction of hydroxylamines to pyrazoles derivatives for the synthesis of β-amino acids. In two cases, these catalysts have proved active but not enantioselective
Guedeney, Nicolas. "Vers la vectorisation des bisphophonates par les peptides de pénétration cellulaire." Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCD024.
Повний текст джерелаNowadays, one of the main strategies for pharmacokinetic modifications of bioactive compounds is their vectorization and the synthesis of prodrug derivatives. This work is focused on the vectorization of phosphorus antitumor agents with cell-penetrating peptides. We have then conjugated aminoalkyl-bisphosphonates with peptidic sequence to modify their retention time and increase their cellular internalization. Several linkers bearing an insaturated carbonyl moiety have been evaluated in conjugation by aza- and thia-Michael addition reaction to obtain a conjugated peptide-alendronate compounds. A prodrug approach has been conducted with the synthesis of bisphosphinate derivatives and an analog of alendronate has been obtained
Léger, Frédéric. "Additions d'énamines β-lithiées sur des esters α, β-éthyléniques. Nouvelles propriétés des énamines β-halogénées". Rouen, 1996. http://www.theses.fr/1996ROUES051.
Повний текст джерелаGoudedranche, Sébastien. "Réactions domino organocatalysées énantiosélectives à partir de cétoamides." Thesis, Aix-Marseille, 2014. http://www.theses.fr/2014AIXM4354.
Повний текст джерелаThis work focused on the development of novel enantioselective transformations combining Multiples Bond-Forming Transformations and organocatalysis which are modern tools of organic synthesis in order to synthetize molecules of structural and biological interests. In this context, we developed two new Michael addition initiated domino reactions. The first one, a domino Michael addition-acylation, allows the synthesis of optically active spiroglutarimides starting from β-ketoamides and α,β-unsaturated acyles cyanides as new biselectrophiles.The second one, a domino Michael addition-hemiaminalizationhemiacetalization, allows the synthesis of seven-membered aza-cycles using α-ketoamides as new bis-nucleophiles
Частини книг з теми "Facile Michael Addition Reaction"
Oare, David A., and Clayton H. Heathcock. "Stereochemistry of the Base-Promoted Michael Addition Reaction." In Topics in Stereochemistry, 227–407. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470147283.ch5.
Повний текст джерелаGuan, Xiaoyuan, Guangxue Chen, Rui Guo, Zhaohui Yu, and Minghui He. "Thiol-ene Michael Addition Reaction Under Phototriggered Base Proliferation." In Lecture Notes in Electrical Engineering, 909–18. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-10-7629-9_113.
Повний текст джерелаTomioka, Kiyoshi. "Five Step Asymmetric Total Synthesis of β-Lycorane Employing Chiral Diether Ligand-Controlled Conjugate Addition-Michael Reaction Cascade." In New Horizons of Process Chemistry, 191–200. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-3421-3_14.
Повний текст джерелаTaber, Douglass F. "The Magnus Synthesis of ( ± )-Codeine." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0088.
Повний текст джерелаLambert, Tristan H. "C–O Ring Formation." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0044.
Повний текст джерелаTaber, Douglass F. "The Deslongchamps Synthesis of (+)-Cassaine." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0091.
Повний текст джерелаTaber, Douglass F. "Enantioselective Synthesis of Alcohols and Amines: The Doi Synthesis of Apratoxin C." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0034.
Повний текст джерелаMarsden, S. P. "Tandem Michael Addition/Intramolecular Aldol Reaction (Robinson Annulation)." In Ketones, 1. Georg Thieme Verlag KG, 2005. http://dx.doi.org/10.1055/sos-sd-026-01026.
Повний текст джерелаTidwell, T. T. "Michael Addition and Elimination Reaction of Alkanoate Esters." In Three Carbon-Heteroatom Bonds: Thio-, Seleno-, and Tellurocarboxylic Acids and Derivatives; Imidic Acids and Derivatives; Ortho Acid Derivatives, 1. Georg Thieme Verlag KG, 2006. http://dx.doi.org/10.1055/sos-sd-023-00542.
Повний текст джерелаFrey, Perry A., and Adrian D. Hegeman. "Addition and Elimination." In Enzymatic Reaction Mechanisms. Oxford University Press, 2007. http://dx.doi.org/10.1093/oso/9780195122589.003.0013.
Повний текст джерелаТези доповідей конференцій з теми "Facile Michael Addition Reaction"
Scott, T. W. "Picosecond Addition and β-Scission Reactions of Thiyl Radicals with Unsaturated Hydrocarbons". У International Conference on Ultrafast Phenomena. Washington, D.C.: Optica Publishing Group, 1986. http://dx.doi.org/10.1364/up.1986.mf7.
Повний текст джерелаForghani, A., L. Garber, C. Chen, R. Devireddy, J. Pojman, and D. Hayes. "In Situ Polymerization of PEGDA Foam for Bone Defects." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-51235.
Повний текст джерелаZhong, Hanyi, Ying Guan, Zhengsong Qiu, Jie Feng, Wenlei Liu, Yuan Wan, and Yubin Zhang. "Improvement of Rheological and Filtration Properties of Water-Based Drilling Fluids Using Bentonite-Hydrothermal Carbon Nanocomposites Under the Ultra-High Temperature and High Pressure Conditions." In SPE/IATMI Asia Pacific Oil & Gas Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/205539-ms.
Повний текст джерелаKote, Prashant, Magdalen Asare, Sahilkumar Chaudhary, Tim Dawsey, and Ram Gupta. "Flame Retardant Polyurethane Foams Using Vegetable Oil-based polyol." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/iefv6816.
Повний текст джерелаShqau, Krenar, and Amy Heintz. "Mixed Ionic Electronic Conductors for Improved Charge Transport in Electrotherapeutic Devices." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3454.
Повний текст джерела